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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CYP1B1 (spascer ID:1545)

Gene summary for CYP1B1

Gene summary

Gene information
	Species	Human
	Gene symbol	CYP1B1
	Gene ID	1545
	Gene name	cytochrome P450 family 1 subfamily B member 1
	Synonyms	ASGD6\|CP1B\|CYPIB1\|GLC3A\|P4501B1
	Cytomap	2p22.2
	Type of gene	protein-coding
	Description	cytochrome P450 1B1aryl hydrocarbon hydroxylasecytochrome P450, family 1, subfamily B, polypeptide 1cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)dioxin-inducible cytochrome p450flavoprotein-linked mono
	Modification date	20220515
	UniProtAcc	Q16678

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CYP1B1	GO:0004497	monooxygenase activity	21873635	Function
CYP1B1	GO:0043231	intracellular membrane-bounded organelle	21873635	Component

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Spatial pattern events for CYP1B1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CYP1B1	Human	Liver	rep_liver1	34417225	1.89e-15
CYP1B1	Human	Uterus	rep_1	34857954	5.02e-14
CYP1B1	Human	Uterus	rep_2	34857954	3.33e-06
CYP1B1	Human	Uterus	rep_3	34857954	2.93e-12
CYP1B1	Human	Breast	CID4465	34493872	4.85e-15
CYP1B1	Human	Breast	CID44971	34493872	1.76e-15
CYP1B1	Human	Breast	CID4535	34493872	1.36e-11
CYP1B1	Human	Lung	rep_1	35355018	7.55e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has CYP1B1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CYP1B1	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
CYP1B1	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
CYP1B1	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
CYP1B1	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Brain	rep_1	7.4e-34
CYP1B1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Brain	rep_1	4.4e-07
CYP1B1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
CYP1B1	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
CYP1B1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Brain	rep_1	3.1e-68
CYP1B1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Blood_Vessel_Morphogenesis	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Cytokine_Production	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Regulation_Of_Vasculature_Development	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
CYP1B1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
CYP1B1	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Brain	st	6.0e-36
CYP1B1	GOBP_Reactive_Oxygen_Species_Metabolic_Process	Human	Brain	st	7.8e-14
CYP1B1	GOBP_Ameboidal_Type_Cell_Migration	Human	Bladder	rep_2	2.7e-06
CYP1B1	GOBP_Blood_Vessel_Morphogenesis	Human	Bladder	rep_2	9.4e-07
CYP1B1	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
CYP1B1	GOBP_External_Encapsulating_Structure_Organization	Human	Bladder	rep_2	8.7e-05
CYP1B1	GOBP_Positive_Regulation_Of_Vascular_Endothelial_Growth_Factor_Production	Human	Bladder	rep_2	7.7e-07
CYP1B1	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Bladder	rep_2	1.6e-04
CYP1B1	GOBP_Regulation_Of_Vasculature_Development	Human	Bladder	rep_2	4.2e-09
CYP1B1	GOBP_Retina_Vasculature_Development_In_Camera_Type_Eye	Human	Bladder	rep_2	1.2e-05
CYP1B1	GOBP_Retina_Vasculature_Morphogenesis_In_Camera_Type_Eye	Human	Bladder	rep_2	1.4e-05
CYP1B1	GOBP_Sensory_Perception_Of_Light_Stimulus	Human	Bladder	rep_2	3.7e-17
CYP1B1	GOBP_Vascular_Endothelial_Growth_Factor_Production	Human	Bladder	rep_2	4.3e-05
CYP1B1	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
CYP1B1	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Bladder	rep_4	1.0e-08
CYP1B1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Blood_Vessel_Morphogenesis	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
CYP1B1	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Cytokine_Production	Human	Liver	rep_1	1.0e-70
CYP1B1	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
CYP1B1	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
CYP1B1	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Liver	rep_1	1.5e-73
CYP1B1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Liver	rep_1	3.7e-85
CYP1B1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
CYP1B1	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
CYP1B1	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Liver	rep_1	1.0e-70
CYP1B1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Liver	rep_1	1.9e-71
CYP1B1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
CYP1B1	GOBP_Regulation_Of_Vasculature_Development	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
CYP1B1	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
CYP1B1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Cytokine_Production	Human	Intestine	rep_colon4	9.0e-12
CYP1B1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	rep_colon4	6.4e-48
CYP1B1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
CYP1B1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
CYP1B1	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	rep_colon4	9.0e-12
CYP1B1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
CYP1B1	GOBP_Regulation_Of_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
CYP1B1	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
CYP1B1	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
CYP1B1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	rep_liver2	1.0e-64
CYP1B1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
CYP1B1	GOBP_Collagen_Fibril_Organization	Human	Intestine	A1	3.1e-32
CYP1B1	GOBP_Apoptotic_Signaling_Pathway	Human	Intestine	A3	7.0e-12
CYP1B1	GOBP_Biological_Adhesion	Human	Intestine	A3	6.7e-11
CYP1B1	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	A3	4.7e-07
CYP1B1	GOBP_Camera_Type_Eye_Development	Human	Intestine	A3	9.7e-08
CYP1B1	GOBP_Cell_Cell_Adhesion	Human	Intestine	A3	2.5e-07
CYP1B1	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
CYP1B1	GOBP_Cellular_Response_To_Chemical_Stress	Human	Intestine	A3	1.1e-11
CYP1B1	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	2.5e-14
CYP1B1	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
CYP1B1	GOBP_Cytokine_Production	Human	Intestine	A3	8.9e-12
CYP1B1	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Intestine	A3	2.5e-16
CYP1B1	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
CYP1B1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	5.4e-19
CYP1B1	GOBP_Nervous_System_Process	Human	Intestine	A3	9.7e-07
CYP1B1	GOBP_Positive_Regulation_Of_Cell_Death	Human	Intestine	A3	4.5e-11
CYP1B1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Intestine	A3	8.0e-16
CYP1B1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
CYP1B1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	A3	3.7e-11
CYP1B1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
CYP1B1	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
CYP1B1	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Intestine	A3	2.5e-12
CYP1B1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	A3	4.8e-12
CYP1B1	GOBP_Regulation_Of_Cell_Adhesion	Human	Intestine	A3	1.5e-10
CYP1B1	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
CYP1B1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	A3	1.1e-09
CYP1B1	GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Intestine	A3	3.1e-19
CYP1B1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
CYP1B1	GOBP_Regulation_Of_Reactive_Oxygen_Species_Metabolic_Process	Human	Intestine	A3	6.2e-19
CYP1B1	GOBP_Response_To_Inorganic_Substance	Human	Intestine	A3	6.8e-07
CYP1B1	GOBP_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	3.2e-15
CYP1B1	GOBP_Response_To_Oxidative_Stress	Human	Intestine	A3	5.4e-18
CYP1B1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
CYP1B1	GOBP_Response_To_Xenobiotic_Stimulus	Human	Intestine	A3	2.5e-09
CYP1B1	GOBP_Retina_Development_In_Camera_Type_Eye	Human	Intestine	A3	1.1e-07
CYP1B1	GOBP_Sensory_Organ_Development	Human	Intestine	A3	1.3e-12
CYP1B1	GOBP_Sensory_System_Development	Human	Intestine	A3	8.7e-09
CYP1B1	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
CYP1B1	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
CYP1B1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	A8	3.3e-08
CYP1B1	GOBP_Arachidonic_Acid_Metabolic_Process	Human	Intestine	A8	4.4e-09
CYP1B1	GOBP_Cellular_Aldehyde_Metabolic_Process	Human	Intestine	A8	5.5e-08
CYP1B1	GOBP_Cellular_Lipid_Metabolic_Process	Human	Intestine	A8	3.8e-13
CYP1B1	GOBP_Cellular_Response_To_Hydrogen_Peroxide	Human	Intestine	A8	5.2e-21
CYP1B1	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Intestine	A8	1.4e-09
CYP1B1	GOBP_Cellular_Response_To_Reactive_Oxygen_Species	Human	Intestine	A8	4.8e-25
CYP1B1	GOBP_Epithelial_Cell_Cell_Adhesion	Human	Intestine	A8	3.4e-10
CYP1B1	GOBP_Epoxygenase_P450_Pathway	Human	Intestine	A8	4.2e-07
CYP1B1	GOBP_Estrogen_Metabolic_Process	Human	Intestine	A8	5.7e-09
CYP1B1	GOBP_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-13
CYP1B1	GOBP_Icosanoid_Metabolic_Process	Human	Intestine	A8	9.6e-13
CYP1B1	GOBP_Lipid_Catabolic_Process	Human	Intestine	A8	3.2e-08
CYP1B1	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
CYP1B1	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	8.2e-09
CYP1B1	GOBP_Membrane_Lipid_Metabolic_Process	Human	Intestine	A8	1.9e-14
CYP1B1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
CYP1B1	GOBP_Negative_Regulation_Of_Cell_Adhesion	Human	Intestine	A8	6.0e-20
CYP1B1	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Intestine	A8	4.6e-12
CYP1B1	GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity	Human	Intestine	A8	2.2e-12
CYP1B1	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
CYP1B1	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Intestine	A8	6.4e-10
CYP1B1	GOBP_Positive_Regulation_Of_Receptor_Signaling_Pathway_Via_Stat	Human	Intestine	A8	5.6e-10
CYP1B1	GOBP_Reactive_Nitrogen_Species_Metabolic_Process	Human	Intestine	A8	1.9e-08
CYP1B1	GOBP_Receptor_Signaling_Pathway_Via_Stat	Human	Intestine	A8	6.8e-12
CYP1B1	GOBP_Regulation_Of_Cell_Adhesion_Mediated_By_Integrin	Human	Intestine	A8	1.6e-09
CYP1B1	GOBP_Regulation_Of_Hormone_Levels	Human	Intestine	A8	3.0e-13
CYP1B1	GOBP_Regulation_Of_Receptor_Signaling_Pathway_Via_Stat	Human	Intestine	A8	9.4e-20
CYP1B1	GOBP_Response_To_Hydrogen_Peroxide	Human	Intestine	A8	7.1e-08
CYP1B1	GOBP_Response_To_Reactive_Oxygen_Species	Human	Intestine	A8	1.4e-28
CYP1B1	GOBP_Response_To_Toxic_Substance	Human	Intestine	A8	8.6e-21
CYP1B1	GOBP_Secondary_Metabolic_Process	Human	Intestine	A8	1.4e-12
CYP1B1	GOBP_Sensory_Perception	Human	Intestine	A8	2.1e-09
CYP1B1	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
CYP1B1	GOBP_Steroid_Metabolic_Process	Human	Intestine	A8	7.9e-16
CYP1B1	GOBP_Sterol_Metabolic_Process	Human	Intestine	A8	1.2e-07
CYP1B1	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	1.4e-12
CYP1B1	GOBP_Vascular_Endothelial_Growth_Factor_Production	Human	Intestine	A8	1.1e-09
CYP1B1	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
CYP1B1	GOBP_Alcohol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
CYP1B1	GOBP_Camera_Type_Eye_Development	Human	Pancreas	PDAC-B-st1	5.7e-05
CYP1B1	GOBP_Isoprenoid_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.0e-05
CYP1B1	GOBP_Receptor_Signaling_Pathway_Via_Stat	Human	Pancreas	PDAC-B-st1	6.9e-05
CYP1B1	GOBP_Response_To_Hydrogen_Peroxide	Human	Pancreas	PDAC-B-st1	7.1e-05
CYP1B1	GOBP_Secondary_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.2e-05
CYP1B1	GOBP_Sterol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	1.9e-05
CYP1B1	GOBP_Collagen_Fibril_Organization	Human	Uterus	rep_1	4.3e-06
CYP1B1	GOBP_Olefinic_Compound_Metabolic_Process	Human	Uterus	rep_1	3.8e-07
CYP1B1	GOBP_Epoxygenase_P450_Pathway	Human	Uterus	rep_25	1.3e-08
CYP1B1	GOBP_Membrane_Lipid_Catabolic_Process	Human	Uterus	rep_25	3.5e-07
CYP1B1	GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity	Human	Uterus	rep_25	7.4e-07
CYP1B1	GOBP_Retina_Vasculature_Morphogenesis_In_Camera_Type_Eye	Human	Uterus	rep_25	6.5e-09
CYP1B1	GOBP_Alcohol_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
CYP1B1	GOBP_Cellular_Aldehyde_Metabolic_Process	Human	Uterus	rep_26	1.2e-06
CYP1B1	GOBP_Cellular_Lipid_Catabolic_Process	Human	Uterus	rep_26	4.6e-06
CYP1B1	GOBP_Endothelial_Cell_Migration	Human	Uterus	rep_26	5.1e-09
CYP1B1	GOBP_Epithelial_Cell_Cell_Adhesion	Human	Uterus	rep_26	1.1e-13
CYP1B1	GOBP_Estrogen_Metabolic_Process	Human	Uterus	rep_26	1.9e-08
CYP1B1	GOBP_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
CYP1B1	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.9e-09
CYP1B1	GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Uterus	rep_26	1.8e-07
CYP1B1	GOBP_Nervous_System_Process	Human	Uterus	rep_26	2.3e-07
CYP1B1	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
CYP1B1	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Uterus	rep_26	2.5e-08
CYP1B1	GOBP_Positive_Regulation_Of_Receptor_Signaling_Pathway_Via_Stat	Human	Uterus	rep_26	2.6e-06
CYP1B1	GOBP_Primary_Alcohol_Metabolic_Process	Human	Uterus	rep_26	2.6e-10
CYP1B1	GOBP_Reactive_Nitrogen_Species_Metabolic_Process	Human	Uterus	rep_26	5.7e-09
CYP1B1	GOBP_Reactive_Oxygen_Species_Metabolic_Process	Human	Uterus	rep_26	4.0e-13
CYP1B1	GOBP_Receptor_Signaling_Pathway_Via_Stat	Human	Uterus	rep_26	7.9e-11
CYP1B1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
CYP1B1	GOBP_Regulation_Of_Reactive_Oxygen_Species_Metabolic_Process	Human	Uterus	rep_26	7.2e-11
CYP1B1	GOBP_Regulation_Of_Receptor_Signaling_Pathway_Via_Stat	Human	Uterus	rep_26	5.7e-07
CYP1B1	GOBP_Response_To_Reactive_Oxygen_Species	Human	Uterus	rep_26	2.1e-12
CYP1B1	GOBP_Response_To_Toxic_Substance	Human	Uterus	rep_26	4.2e-06
CYP1B1	GOBP_Secondary_Metabolic_Process	Human	Uterus	rep_26	1.7e-08
CYP1B1	GOBP_Steroid_Metabolic_Process	Human	Uterus	rep_26	1.0e-07
CYP1B1	GOBP_Sterol_Metabolic_Process	Human	Uterus	rep_26	4.7e-08
CYP1B1	GOBP_Terpenoid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
CYP1B1	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	3.3e-07
CYP1B1	GOBP_Biological_Adhesion	Human	Uterus	rep_29	3.3e-06
CYP1B1	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Uterus	rep_29	1.6e-12
CYP1B1	GOBP_Omega_Hydroxylase_P450_Pathway	Human	Uterus	rep_29	4.8e-06
CYP1B1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
CYP1B1	GOBP_Retina_Vasculature_Development_In_Camera_Type_Eye	Human	Uterus	rep_29	1.2e-06
CYP1B1	GOBP_Ameboidal_Type_Cell_Migration	Human	Breast	rep_1	6.7e-99
CYP1B1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Breast	rep_1	1.9e-98
CYP1B1	GOBP_Arachidonic_Acid_Metabolic_Process	Human	Breast	rep_1	1.2e-10
CYP1B1	GOBP_Biological_Adhesion	Human	Breast	rep_1	4.0e-110
CYP1B1	GOBP_Blood_Vessel_Morphogenesis	Human	Breast	rep_1	1.5e-106
CYP1B1	GOBP_Cell_Adhesion_Mediated_By_Integrin	Human	Breast	rep_1	5.2e-135
CYP1B1	GOBP_Cell_Cell_Adhesion	Human	Breast	rep_1	3.6e-45
CYP1B1	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
CYP1B1	GOBP_Cellular_Hormone_Metabolic_Process	Human	Breast	rep_1	3.2e-25
CYP1B1	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
CYP1B1	GOBP_Cytokine_Production	Human	Breast	rep_1	6.5e-12
CYP1B1	GOBP_Endothelial_Cell_Migration	Human	Breast	rep_1	8.0e-84
CYP1B1	GOBP_Epoxygenase_P450_Pathway	Human	Breast	rep_1	1.3e-28
CYP1B1	GOBP_Estrogen_Metabolic_Process	Human	Breast	rep_1	1.3e-04
CYP1B1	GOBP_External_Encapsulating_Structure_Organization	Human	Breast	rep_1	2.8e-108
CYP1B1	GOBP_Hormone_Metabolic_Process	Human	Breast	rep_1	2.8e-38
CYP1B1	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
CYP1B1	GOBP_Negative_Regulation_Of_Cell_Adhesion	Human	Breast	rep_1	2.9e-92
CYP1B1	GOBP_Negative_Regulation_Of_Cell_Adhesion_Mediated_By_Integrin	Human	Breast	rep_1	1.6e-90
CYP1B1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	1.3e-54
CYP1B1	GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Breast	rep_1	1.1e-71
CYP1B1	GOBP_Negative_Regulation_Of_Molecular_Function	Human	Breast	rep_1	7.1e-11
CYP1B1	GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity	Human	Breast	rep_1	2.1e-20
CYP1B1	GOBP_Nervous_System_Process	Human	Breast	rep_1	1.2e-04
CYP1B1	GOBP_Omega_Hydroxylase_P450_Pathway	Human	Breast	rep_1	1.3e-18
CYP1B1	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Breast	rep_1	7.3e-16
CYP1B1	GOBP_Positive_Regulation_Of_Cell_Death	Human	Breast	rep_1	2.2e-15
CYP1B1	GOBP_Positive_Regulation_Of_Cytokine_Production	Human	Breast	rep_1	6.5e-10
CYP1B1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
CYP1B1	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Breast	rep_1	7.3e-07
CYP1B1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
CYP1B1	GOBP_Positive_Regulation_Of_Receptor_Signaling_Pathway_Via_Stat	Human	Breast	rep_1	3.9e-69
CYP1B1	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Breast	rep_1	4.6e-40
CYP1B1	GOBP_Reactive_Nitrogen_Species_Metabolic_Process	Human	Breast	rep_1	4.9e-45
CYP1B1	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Breast	rep_1	3.9e-78
CYP1B1	GOBP_Reactive_Oxygen_Species_Metabolic_Process	Human	Breast	rep_1	2.2e-98
CYP1B1	GOBP_Receptor_Signaling_Pathway_Via_Stat	Human	Breast	rep_1	3.3e-77
CYP1B1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Breast	rep_1	4.6e-22
CYP1B1	GOBP_Regulation_Of_Cell_Adhesion	Human	Breast	rep_1	1.7e-16
CYP1B1	GOBP_Regulation_Of_Cell_Adhesion_Mediated_By_Integrin	Human	Breast	rep_1	7.8e-118
CYP1B1	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Breast	rep_1	5.5e-21
CYP1B1	GOBP_Regulation_Of_Hormone_Levels	Human	Breast	rep_1	1.1e-80
CYP1B1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
CYP1B1	GOBP_Regulation_Of_Reactive_Oxygen_Species_Metabolic_Process	Human	Breast	rep_1	1.3e-73
CYP1B1	GOBP_Regulation_Of_Receptor_Signaling_Pathway_Via_Stat	Human	Breast	rep_1	2.8e-58
CYP1B1	GOBP_Regulation_Of_Vasculature_Development	Human	Breast	rep_1	1.9e-30
CYP1B1	GOBP_Retina_Vasculature_Development_In_Camera_Type_Eye	Human	Breast	rep_1	7.7e-49
CYP1B1	GOBP_Retina_Vasculature_Morphogenesis_In_Camera_Type_Eye	Human	Breast	rep_1	2.3e-19
CYP1B1	GOBP_Secondary_Metabolic_Process	Human	Breast	rep_1	3.3e-13
CYP1B1	GOBP_Sensory_Perception_Of_Light_Stimulus	Human	Breast	rep_1	8.2e-37
CYP1B1	GOBP_Supramolecular_Fiber_Organization	Human	Breast	rep_1	2.8e-72
CYP1B1	GOBP_Tissue_Migration	Human	Breast	rep_1	7.3e-113
CYP1B1	GOBP_Toxin_Metabolic_Process	Human	Breast	rep_1	1.6e-68
CYP1B1	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
CYP1B1	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
CYP1B1	GOBP_Vascular_Endothelial_Growth_Factor_Production	Human	Breast	rep_1	8.8e-77
CYP1B1	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
CYP1B1	GOBP_Retinal_Blood_Vessel_Morphogenesis	Human	Breast	rep_3	7.0e-23
CYP1B1	GOBP_Cellular_Lipid_Metabolic_Process	Human	Breast	rep_5	2.6e-07
CYP1B1	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	5.1e-18
CYP1B1	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.9e-11
CYP1B1	GOBP_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	1.2e-06
CYP1B1	GOBP_Icosanoid_Metabolic_Process	Human	Breast	rep_5	2.9e-07
CYP1B1	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
CYP1B1	GOBP_Membrane_Lipid_Catabolic_Process	Human	Breast	rep_5	4.9e-09
CYP1B1	GOBP_Membrane_Lipid_Metabolic_Process	Human	Breast	rep_5	1.9e-17
CYP1B1	GOBP_Negative_Regulation_Of_Locomotion	Human	Breast	rep_5	1.3e-13
CYP1B1	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
CYP1B1	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
CYP1B1	GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Breast	rep_5	8.2e-07
CYP1B1	GOBP_Response_To_Inorganic_Substance	Human	Breast	rep_5	1.8e-10
CYP1B1	GOBP_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	7.5e-14
CYP1B1	GOBP_Response_To_Oxidative_Stress	Human	Breast	rep_5	1.0e-04
CYP1B1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
CYP1B1	GOBP_Response_To_Toxic_Substance	Human	Breast	rep_5	1.2e-07
CYP1B1	GOBP_Response_To_Xenobiotic_Stimulus	Human	Breast	rep_5	2.9e-05
CYP1B1	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	3.8e-09
CYP1B1	GOBP_Alcohol_Metabolic_Process	Human	Breast	rep_6	1.3e-04
CYP1B1	GOBP_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	4.8e-09
CYP1B1	GOBP_Camera_Type_Eye_Development	Human	Breast	rep_6	9.2e-06
CYP1B1	GOBP_Cell_Death_In_Response_To_Oxidative_Stress	Human	Breast	rep_6	1.9e-04
CYP1B1	GOBP_Cellular_Aldehyde_Metabolic_Process	Human	Breast	rep_6	3.0e-09
CYP1B1	GOBP_Cellular_Lipid_Catabolic_Process	Human	Breast	rep_6	3.6e-11
CYP1B1	GOBP_Cellular_Response_To_Chemical_Stress	Human	Breast	rep_6	3.6e-05
CYP1B1	GOBP_Cellular_Response_To_Hydrogen_Peroxide	Human	Breast	rep_6	2.8e-05
CYP1B1	GOBP_Cellular_Response_To_Reactive_Oxygen_Species	Human	Breast	rep_6	1.3e-05
CYP1B1	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Breast	rep_6	2.7e-08
CYP1B1	GOBP_Isoprenoid_Metabolic_Process	Human	Breast	rep_6	3.7e-11
CYP1B1	GOBP_Lipid_Catabolic_Process	Human	Breast	rep_6	2.9e-05
CYP1B1	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Breast	rep_6	6.3e-10
CYP1B1	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
CYP1B1	GOBP_Olefinic_Compound_Metabolic_Process	Human	Breast	rep_6	1.5e-08
CYP1B1	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
CYP1B1	GOBP_Positive_Regulation_Of_Vascular_Endothelial_Growth_Factor_Production	Human	Breast	rep_6	1.9e-04
CYP1B1	GOBP_Primary_Alcohol_Metabolic_Process	Human	Breast	rep_6	2.0e-08
CYP1B1	GOBP_Response_To_Hydrogen_Peroxide	Human	Breast	rep_6	6.6e-04
CYP1B1	GOBP_Retinal_Metabolic_Process	Human	Breast	rep_6	1.2e-04
CYP1B1	GOBP_Sensory_Organ_Development	Human	Breast	rep_6	1.3e-09
CYP1B1	GOBP_Sensory_System_Development	Human	Breast	rep_6	8.2e-06
CYP1B1	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
CYP1B1	GOBP_Steroid_Metabolic_Process	Human	Breast	rep_6	6.6e-05
CYP1B1	GOBP_Sterol_Metabolic_Process	Human	Breast	rep_6	5.3e-04
CYP1B1	GOBP_Terpenoid_Metabolic_Process	Human	Breast	rep_6	1.1e-10
CYP1B1	GOBP_Epithelial_Cell_Cell_Adhesion	Human	Skin	P2_rep2	4.0e-12
CYP1B1	GOBP_Positive_Regulation_Of_Vascular_Endothelial_Growth_Factor_Production	Human	Skin	P2_rep2	5.6e-12
CYP1B1	GOBP_Primary_Alcohol_Metabolic_Process	Human	Skin	P2_rep3	4.9e-08
CYP1B1	GOBP_Retinol_Metabolic_Process	Human	Skin	P2_rep3	1.3e-08
CYP1B1	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Skin	P2_rep3	8.1e-08
CYP1B1	GOBP_Endothelial_Cell_Migration	Human	Skin	P5_rep2	2.0e-08
CYP1B1	GOBP_Intrinsic_Apoptotic_Signaling_Pathway	Human	Skin	P9_rep3	4.3e-09
CYP1B1	GOBP_Reactive_Nitrogen_Species_Metabolic_Process	Human	Skin	P10_rep1	7.1e-14
CYP1B1	GOBP_Retina_Vasculature_Development_In_Camera_Type_Eye	Human	Skin	P10_rep1	1.6e-14
CYP1B1	GOBP_Retina_Vasculature_Morphogenesis_In_Camera_Type_Eye	Human	Skin	P10_rep1	1.5e-19
CYP1B1	GOBP_Toxin_Metabolic_Process	Human	Skin	P10_rep1	3.1e-20
CYP1B1	GOBP_Negative_Regulation_Of_Cell_Adhesion_Mediated_By_Integrin	Human	Skin	P10_rep2	4.1e-12
CYP1B1	GOBP_Retinal_Blood_Vessel_Morphogenesis	Human	Skin	P10_rep2	1.3e-11
CYP1B1	GOBP_Vascular_Endothelial_Growth_Factor_Production	Human	Skin	P10_rep2	4.9e-16
CYP1B1	GOBP_Regulation_Of_Cell_Adhesion_Mediated_By_Integrin	Human	Skin	P10_rep3	1.0e-10
CYP1B1	GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity	Human	Lung	rep_1	1.9e-10
CYP1B1	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08
CYP1B1	GOBP_Biological_Adhesion	Human	Lung	rep_2	6.6e-07
CYP1B1	GOBP_Cell_Cell_Adhesion	Human	Lung	rep_2	5.3e-07
CYP1B1	GOBP_Icosanoid_Metabolic_Process	Human	Lung	rep_2	4.6e-07
CYP1B1	GOBP_Lipid_Catabolic_Process	Human	Lung	rep_2	1.4e-09
CYP1B1	GOBP_Positive_Regulation_Of_Cell_Death	Human	Lung	rep_2	3.0e-07
CYP1B1	GOBP_Regulation_Of_Hormone_Levels	Human	Lung	rep_2	1.6e-07
CYP1B1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07

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CYP1B1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CYP1B1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CYP1B1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CYP1B1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CYP1B1	Q16678	DB07776	Flavone	Cytochrome P450 1B1	SmallMoleculeDrug	approved\|experimental
CYP1B1	Q16678	DB09061	Cannabidiol	Cytochrome P450 1B1	SmallMoleculeDrug	approved\|investigational

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Related Diseases for CYP1B1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CYP1B1	C1856439	GLAUCOMA 3, PRIMARY CONGENITAL, A	22	CTD_human;GENOMICS_ENGLAND;UNIPROT
CYP1B1	C0344559	Irido-corneo-trabecular dysgenesis (disorder)	3	ORPHANET
CYP1B1	C0006142	Malignant neoplasm of breast	2	CTD_human
CYP1B1	C0678222	Breast Carcinoma	2	CTD_human
CYP1B1	C1257931	Mammary Neoplasms, Human	2	CTD_human
CYP1B1	C1458155	Mammary Neoplasms	2	CTD_human
CYP1B1	C1533041	Primary congenital glaucoma	2	GENOMICS_ENGLAND
CYP1B1	C2981140	Glaucoma of childhood	2	ORPHANET
CYP1B1	C4310809	ANTERIOR SEGMENT DYSGENESIS 5	2	GENOMICS_ENGLAND
CYP1B1	C4704874	Mammary Carcinoma, Human	2	CTD_human
CYP1B1	C0001430	Adenoma	1	CTD_human
CYP1B1	C0007137	Squamous cell carcinoma	1	CTD_human
CYP1B1	C0009402	Colorectal Carcinoma	1	CTD_human
CYP1B1	C0009404	Colorectal Neoplasms	1	CTD_human
CYP1B1	C0011616	Contact Dermatitis	1	CTD_human
CYP1B1	C0015695	Fatty Liver	1	CTD_human
CYP1B1	C0018800	Cardiomegaly	1	CTD_human
CYP1B1	C0019209	Hepatomegaly	1	CTD_human
CYP1B1	C0020302	Hydrophthalmos	1	ORPHANET
CYP1B1	C0023452	Childhood Acute Lymphoblastic Leukemia	1	CTD_human
CYP1B1	C0023453	L2 Acute Lymphoblastic Leukemia	1	CTD_human
CYP1B1	C0024121	Lung Neoplasms	1	CTD_human
CYP1B1	C0025202	melanoma	1	CTD_human
CYP1B1	C0026640	Mouth Neoplasms	1	CTD_human
CYP1B1	C0028754	Obesity	1	CTD_human
CYP1B1	C0033578	Prostatic Neoplasms	1	CTD_human
CYP1B1	C0086132	Depressive Symptoms	1	PSYGENET
CYP1B1	C0153381	Malignant neoplasm of mouth	1	CTD_human
CYP1B1	C0162351	Contact hypersensitivity	1	CTD_human
CYP1B1	C0205646	Adenoma, Basal Cell	1	CTD_human
CYP1B1	C0205647	Follicular adenoma	1	CTD_human
CYP1B1	C0205648	Adenoma, Microcystic	1	CTD_human
CYP1B1	C0205649	Adenoma, Monomorphic	1	CTD_human
CYP1B1	C0205650	Papillary adenoma	1	CTD_human
CYP1B1	C0205651	Adenoma, Trabecular	1	CTD_human
CYP1B1	C0242379	Malignant neoplasm of lung	1	CTD_human
CYP1B1	C0271650	Impaired glucose tolerance	1	CTD_human
CYP1B1	C0376358	Malignant neoplasm of prostate	1	CTD_human
CYP1B1	C0919267	ovarian neoplasm	1	CTD_human
CYP1B1	C1140680	Malignant neoplasm of ovary	1	CTD_human
CYP1B1	C1383860	Cardiac Hypertrophy	1	CTD_human
CYP1B1	C1842028	GLAUCOMA 1, OPEN ANGLE, A	1	UNIPROT
CYP1B1	C1961102	Precursor Cell Lymphoblastic Leukemia Lymphoma	1	CTD_human
CYP1B1	C2711227	Steatohepatitis	1	CTD_human