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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CYP1A2 (spascer ID:1544)

Gene summary for CYP1A2

Gene summary

Gene information
	Species	Human
	Gene symbol	CYP1A2
	Gene ID	1544
	Gene name	cytochrome P450 family 1 subfamily A member 2
	Synonyms	CP12\|CYPIA2\|P3-450\|P450(PA)
	Cytomap	15q24.1
	Type of gene	protein-coding
	Description	cytochrome P450 1A2P450 form 4aryl hydrocarbon hydroxylasecholesterol 25-hydroxylasecytochrome P(3)450cytochrome P450 4cytochrome P450, family 1, subfamily A, polypeptide 2cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2cy
	Modification date	20220513
	UniProtAcc	P05177

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CYP1A2	GO:0004497	monooxygenase activity	21873635	Function
CYP1A2	GO:0043231	intracellular membrane-bounded organelle	21873635	Component

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Spatial pattern events for CYP1A2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CYP1A2	Human	Liver	rep_1	34792289	2.38e-14
CYP1A2	Human	Liver	rep_liver2	34417225	6.98e-16
CYP1A2	Human	Liver	rep_liver3	34417225	3.51e-15
CYP1A2	Human	Liver	rep_liver4	34417225	7.71e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E

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Spatial pattern pathway has CYP1A2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CYP1A2	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
CYP1A2	GOBP_Response_To_Bacterium	Human	Brain	rep_1	3.1e-16
CYP1A2	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
CYP1A2	GOBP_Response_To_Lipid	Human	Brain	rep_10	2.8e-23
CYP1A2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
CYP1A2	GOBP_Hydrogen_Peroxide_Biosynthetic_Process	Human	Brain	st	4.1e-14
CYP1A2	GOBP_Hydrogen_Peroxide_Metabolic_Process	Human	Brain	st	1.5e-10
CYP1A2	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Brain	st	6.0e-36
CYP1A2	GOBP_Reactive_Oxygen_Species_Metabolic_Process	Human	Brain	st	7.8e-14
CYP1A2	GOBP_Alkaloid_Metabolic_Process	Human	Bladder	rep_2	6.1e-07
CYP1A2	GOBP_Cellular_Response_To_Copper_Ion	Human	Bladder	rep_2	6.8e-05
CYP1A2	GOBP_Response_To_Estradiol	Human	Bladder	rep_2	1.6e-18
CYP1A2	GOBP_Response_To_Immobilization_Stress	Human	Bladder	rep_2	3.6e-06
CYP1A2	GOBP_Cellular_Respiration	Human	Bladder	rep_4	2.0e-15
CYP1A2	GOBP_Electron_Transport_Chain	Human	Bladder	rep_4	1.0e-20
CYP1A2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Bladder	rep_4	1.5e-12
CYP1A2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Bladder	rep_4	3.4e-12
CYP1A2	GOBP_Hydrogen_Peroxide_Biosynthetic_Process	Human	Bladder	rep_4	3.1e-07
CYP1A2	GOBP_Hydrogen_Peroxide_Metabolic_Process	Human	Bladder	rep_4	3.8e-08
CYP1A2	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Bladder	rep_4	1.0e-08
CYP1A2	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
CYP1A2	GOBP_Response_To_Bacterium	Human	Liver	rep_1	9.4e-68
CYP1A2	GOBP_Response_To_Lipid	Human	Liver	rep_1	3.0e-55
CYP1A2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
CYP1A2	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
CYP1A2	GOBP_Response_To_Bacterium	Human	Intestine	rep_colon4	1.0e-26
CYP1A2	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
CYP1A2	GOBP_Response_To_Lipid	Human	Intestine	rep_liver2	3.7e-39
CYP1A2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
CYP1A2	GOBP_Cellular_Respiration	Human	Intestine	A3	6.2e-15
CYP1A2	GOBP_Electron_Transport_Chain	Human	Intestine	A3	1.4e-19
CYP1A2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Intestine	A3	2.5e-12
CYP1A2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Intestine	A3	4.3e-14
CYP1A2	GOBP_Lipid_Biosynthetic_Process	Human	Intestine	A3	5.0e-07
CYP1A2	GOBP_Methylation	Human	Intestine	A3	5.9e-09
CYP1A2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Intestine	A3	5.9e-24
CYP1A2	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Intestine	A3	2.5e-12
CYP1A2	GOBP_Response_To_Inorganic_Substance	Human	Intestine	A3	6.8e-07
CYP1A2	GOBP_Response_To_Lipid	Human	Intestine	A3	1.7e-09
CYP1A2	GOBP_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	3.2e-15
CYP1A2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
CYP1A2	GOBP_Response_To_Xenobiotic_Stimulus	Human	Intestine	A3	2.5e-09
CYP1A2	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
CYP1A2	GOBP_Arachidonic_Acid_Metabolic_Process	Human	Intestine	A8	4.4e-09
CYP1A2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Intestine	A8	3.8e-13
CYP1A2	GOBP_Cellular_Response_To_Cadmium_Ion	Human	Intestine	A8	2.1e-09
CYP1A2	GOBP_Cellular_Response_To_Copper_Ion	Human	Intestine	A8	4.3e-14
CYP1A2	GOBP_Cellular_Response_To_Inorganic_Substance	Human	Intestine	A8	1.5e-12
CYP1A2	GOBP_Demethylation	Human	Intestine	A8	2.5e-15
CYP1A2	GOBP_Epoxygenase_P450_Pathway	Human	Intestine	A8	4.2e-07
CYP1A2	GOBP_Estrogen_Metabolic_Process	Human	Intestine	A8	5.7e-09
CYP1A2	GOBP_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-13
CYP1A2	GOBP_Hydrogen_Peroxide_Biosynthetic_Process	Human	Intestine	A8	5.0e-11
CYP1A2	GOBP_Icosanoid_Metabolic_Process	Human	Intestine	A8	9.6e-13
CYP1A2	GOBP_Lipid_Catabolic_Process	Human	Intestine	A8	3.2e-08
CYP1A2	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
CYP1A2	GOBP_Long_Chain_Fatty_Acid_Biosynthetic_Process	Human	Intestine	A8	1.9e-16
CYP1A2	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	8.2e-09
CYP1A2	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
CYP1A2	GOBP_Organic_Acid_Biosynthetic_Process	Human	Intestine	A8	2.1e-08
CYP1A2	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
CYP1A2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Intestine	A8	6.4e-10
CYP1A2	GOBP_Oxidative_Demethylation	Human	Intestine	A8	4.0e-13
CYP1A2	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Human	Intestine	A8	2.0e-11
CYP1A2	GOBP_Post_Embryonic_Development	Human	Intestine	A8	1.1e-11
CYP1A2	GOBP_Regulation_Of_Hormone_Levels	Human	Intestine	A8	3.0e-13
CYP1A2	GOBP_Response_To_Bacterium	Human	Intestine	A8	3.3e-17
CYP1A2	GOBP_Response_To_Cadmium_Ion	Human	Intestine	A8	2.1e-09
CYP1A2	GOBP_Response_To_Copper_Ion	Human	Intestine	A8	2.5e-12
CYP1A2	GOBP_Response_To_Immobilization_Stress	Human	Intestine	A8	4.5e-28
CYP1A2	GOBP_Response_To_Metal_Ion	Human	Intestine	A8	2.1e-21
CYP1A2	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Human	Intestine	A8	1.0e-14
CYP1A2	GOBP_Secondary_Metabolic_Process	Human	Intestine	A8	1.4e-12
CYP1A2	GOBP_Secondary_Metabolite_Biosynthetic_Process	Human	Intestine	A8	1.6e-16
CYP1A2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
CYP1A2	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
CYP1A2	GOBP_Steroid_Catabolic_Process	Human	Intestine	A8	2.0e-18
CYP1A2	GOBP_Steroid_Metabolic_Process	Human	Intestine	A8	7.9e-16
CYP1A2	GOBP_Sterol_Metabolic_Process	Human	Intestine	A8	1.2e-07
CYP1A2	GOBP_Tetrapyrrole_Metabolic_Process	Human	Intestine	A8	2.2e-10
CYP1A2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Intestine	A8	1.4e-12
CYP1A2	GOBP_Alcohol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
CYP1A2	GOBP_Demethylation	Human	Pancreas	PDAC-B-st1	4.7e-05
CYP1A2	GOBP_Isoprenoid_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.0e-05
CYP1A2	GOBP_Post_Embryonic_Development	Human	Pancreas	PDAC-B-st1	1.2e-05
CYP1A2	GOBP_Secondary_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.2e-05
CYP1A2	GOBP_Sterol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	1.9e-05
CYP1A2	GOBP_Olefinic_Compound_Metabolic_Process	Human	Uterus	rep_1	3.8e-07
CYP1A2	GOBP_Cellular_Response_To_Cadmium_Ion	Human	Uterus	rep_25	3.4e-06
CYP1A2	GOBP_Cellular_Response_To_Copper_Ion	Human	Uterus	rep_25	1.4e-10
CYP1A2	GOBP_Epoxygenase_P450_Pathway	Human	Uterus	rep_25	1.3e-08
CYP1A2	GOBP_Response_To_Copper_Ion	Human	Uterus	rep_25	6.9e-12
CYP1A2	GOBP_Alcohol_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
CYP1A2	GOBP_Cellular_Respiration	Human	Uterus	rep_26	3.7e-07
CYP1A2	GOBP_Electron_Transport_Chain	Human	Uterus	rep_26	1.9e-08
CYP1A2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Uterus	rep_26	7.2e-06
CYP1A2	GOBP_Estrogen_Metabolic_Process	Human	Uterus	rep_26	1.9e-08
CYP1A2	GOBP_Fatty_Acid_Biosynthetic_Process	Human	Uterus	rep_26	9.2e-10
CYP1A2	GOBP_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
CYP1A2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Uterus	rep_26	1.8e-06
CYP1A2	GOBP_Hydrogen_Peroxide_Metabolic_Process	Human	Uterus	rep_26	6.5e-09
CYP1A2	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	1.9e-09
CYP1A2	GOBP_Methylation	Human	Uterus	rep_26	1.9e-06
CYP1A2	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	1.0e-07
CYP1A2	GOBP_Organic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	2.3e-06
CYP1A2	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
CYP1A2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Uterus	rep_26	2.6e-06
CYP1A2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Uterus	rep_26	2.5e-08
CYP1A2	GOBP_Oxidative_Demethylation	Human	Uterus	rep_26	2.8e-07
CYP1A2	GOBP_Primary_Alcohol_Metabolic_Process	Human	Uterus	rep_26	2.6e-10
CYP1A2	GOBP_Reactive_Oxygen_Species_Metabolic_Process	Human	Uterus	rep_26	4.0e-13
CYP1A2	GOBP_Respiratory_System_Development	Human	Uterus	rep_26	1.3e-07
CYP1A2	GOBP_Secondary_Metabolic_Process	Human	Uterus	rep_26	1.7e-08
CYP1A2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
CYP1A2	GOBP_Steroid_Metabolic_Process	Human	Uterus	rep_26	1.0e-07
CYP1A2	GOBP_Sterol_Metabolic_Process	Human	Uterus	rep_26	4.7e-08
CYP1A2	GOBP_Terpenoid_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
CYP1A2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Uterus	rep_26	3.3e-07
CYP1A2	GOBP_Response_To_Bacterium	Human	Uterus	rep_28	3.0e-06
CYP1A2	GOBP_Long_Chain_Fatty_Acid_Biosynthetic_Process	Human	Uterus	rep_29	2.2e-08
CYP1A2	GOBP_Omega_Hydroxylase_P450_Pathway	Human	Uterus	rep_29	4.8e-06
CYP1A2	GOBP_Alkaloid_Metabolic_Process	Human	Breast	rep_1	5.5e-16
CYP1A2	GOBP_Arachidonic_Acid_Metabolic_Process	Human	Breast	rep_1	1.2e-10
CYP1A2	GOBP_Cellular_Hormone_Metabolic_Process	Human	Breast	rep_1	3.2e-25
CYP1A2	GOBP_Epoxygenase_P450_Pathway	Human	Breast	rep_1	1.3e-28
CYP1A2	GOBP_Estrogen_Metabolic_Process	Human	Breast	rep_1	1.3e-04
CYP1A2	GOBP_Hormone_Metabolic_Process	Human	Breast	rep_1	2.8e-38
CYP1A2	GOBP_Hydrogen_Peroxide_Biosynthetic_Process	Human	Breast	rep_1	7.9e-103
CYP1A2	GOBP_Hydrogen_Peroxide_Metabolic_Process	Human	Breast	rep_1	1.1e-76
CYP1A2	GOBP_Omega_Hydroxylase_P450_Pathway	Human	Breast	rep_1	1.3e-18
CYP1A2	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Breast	rep_1	7.3e-16
CYP1A2	GOBP_Reactive_Oxygen_Species_Biosynthetic_Process	Human	Breast	rep_1	3.9e-78
CYP1A2	GOBP_Reactive_Oxygen_Species_Metabolic_Process	Human	Breast	rep_1	2.2e-98
CYP1A2	GOBP_Regulation_Of_Hormone_Levels	Human	Breast	rep_1	1.1e-80
CYP1A2	GOBP_Respiratory_System_Development	Human	Breast	rep_1	3.3e-47
CYP1A2	GOBP_Response_To_Metal_Ion	Human	Breast	rep_1	3.0e-20
CYP1A2	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Human	Breast	rep_1	1.2e-20
CYP1A2	GOBP_Secondary_Metabolic_Process	Human	Breast	rep_1	3.3e-13
CYP1A2	GOBP_Steroid_Catabolic_Process	Human	Breast	rep_1	1.0e-23
CYP1A2	GOBP_Toxin_Metabolic_Process	Human	Breast	rep_1	1.6e-68
CYP1A2	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
CYP1A2	GOBP_Response_To_Immobilization_Stress	Human	Breast	rep_3	5.2e-20
CYP1A2	GOBP_Cellular_Lipid_Metabolic_Process	Human	Breast	rep_5	2.6e-07
CYP1A2	GOBP_Electron_Transport_Chain	Human	Breast	rep_5	6.2e-04
CYP1A2	GOBP_Fatty_Acid_Biosynthetic_Process	Human	Breast	rep_5	2.8e-12
CYP1A2	GOBP_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	1.2e-06
CYP1A2	GOBP_Icosanoid_Metabolic_Process	Human	Breast	rep_5	2.9e-07
CYP1A2	GOBP_Lipid_Biosynthetic_Process	Human	Breast	rep_5	7.0e-04
CYP1A2	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
CYP1A2	GOBP_Monocarboxylic_Acid_Biosynthetic_Process	Human	Breast	rep_5	2.9e-17
CYP1A2	GOBP_Organic_Acid_Biosynthetic_Process	Human	Breast	rep_5	3.5e-09
CYP1A2	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	7.6e-07
CYP1A2	GOBP_Response_To_Copper_Ion	Human	Breast	rep_5	3.0e-06
CYP1A2	GOBP_Response_To_Estradiol	Human	Breast	rep_5	6.9e-16
CYP1A2	GOBP_Response_To_Inorganic_Substance	Human	Breast	rep_5	1.8e-10
CYP1A2	GOBP_Response_To_Lipid	Human	Breast	rep_5	1.6e-10
CYP1A2	GOBP_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	7.5e-14
CYP1A2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
CYP1A2	GOBP_Response_To_Xenobiotic_Stimulus	Human	Breast	rep_5	2.9e-05
CYP1A2	GOBP_Tetrapyrrole_Metabolic_Process	Human	Breast	rep_5	1.1e-05
CYP1A2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Breast	rep_5	3.8e-09
CYP1A2	GOBP_Alcohol_Metabolic_Process	Human	Breast	rep_6	1.3e-04
CYP1A2	GOBP_Cellular_Respiration	Human	Breast	rep_6	2.2e-06
CYP1A2	GOBP_Cellular_Response_To_Cadmium_Ion	Human	Breast	rep_6	7.6e-08
CYP1A2	GOBP_Cellular_Response_To_Copper_Ion	Human	Breast	rep_6	1.3e-07
CYP1A2	GOBP_Demethylation	Human	Breast	rep_6	3.7e-06
CYP1A2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Breast	rep_6	5.2e-08
CYP1A2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Breast	rep_6	7.1e-09
CYP1A2	GOBP_Isoprenoid_Metabolic_Process	Human	Breast	rep_6	3.7e-11
CYP1A2	GOBP_Lipid_Catabolic_Process	Human	Breast	rep_6	2.9e-05
CYP1A2	GOBP_Long_Chain_Fatty_Acid_Biosynthetic_Process	Human	Breast	rep_6	5.2e-08
CYP1A2	GOBP_Long_Chain_Fatty_Acid_Metabolic_Process	Human	Breast	rep_6	6.3e-10
CYP1A2	GOBP_Methylation	Human	Breast	rep_6	1.7e-06
CYP1A2	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
CYP1A2	GOBP_Olefinic_Compound_Metabolic_Process	Human	Breast	rep_6	1.5e-08
CYP1A2	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
CYP1A2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Human	Breast	rep_6	7.7e-08
CYP1A2	GOBP_Oxidative_Demethylation	Human	Breast	rep_6	1.3e-12
CYP1A2	GOBP_Post_Embryonic_Development	Human	Breast	rep_6	9.9e-05
CYP1A2	GOBP_Primary_Alcohol_Metabolic_Process	Human	Breast	rep_6	2.0e-08
CYP1A2	GOBP_Response_To_Cadmium_Ion	Human	Breast	rep_6	7.8e-04
CYP1A2	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
CYP1A2	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
CYP1A2	GOBP_Steroid_Metabolic_Process	Human	Breast	rep_6	6.6e-05
CYP1A2	GOBP_Sterol_Metabolic_Process	Human	Breast	rep_6	5.3e-04
CYP1A2	GOBP_Terpenoid_Metabolic_Process	Human	Breast	rep_6	1.1e-10
CYP1A2	GOBP_Response_To_Cadmium_Ion	Human	Skin	P2_rep2	2.1e-08
CYP1A2	GOBP_Primary_Alcohol_Metabolic_Process	Human	Skin	P2_rep3	4.9e-08
CYP1A2	GOBP_Retinol_Metabolic_Process	Human	Skin	P2_rep3	1.3e-08
CYP1A2	GOBP_Unsaturated_Fatty_Acid_Metabolic_Process	Human	Skin	P2_rep3	8.1e-08
CYP1A2	GOBP_Long_Chain_Fatty_Acid_Biosynthetic_Process	Human	Skin	P5_rep1	5.9e-10
CYP1A2	GOBP_Cellular_Response_To_Copper_Ion	Human	Skin	P10_rep1	8.7e-09
CYP1A2	GOBP_Response_To_Immobilization_Stress	Human	Skin	P10_rep1	1.1e-11
CYP1A2	GOBP_Toxin_Metabolic_Process	Human	Skin	P10_rep1	3.1e-20
CYP1A2	GOBP_Oxidative_Demethylation	Human	Skin	P10_rep2	6.8e-13
CYP1A2	GOBP_Response_To_Bacterium	Human	Lung	rep_1	1.1e-09
CYP1A2	GOBP_Response_To_Lipid	Human	Lung	rep_1	1.8e-09
CYP1A2	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Human	Lung	rep_1	1.7e-07
CYP1A2	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08
CYP1A2	GOBP_Fatty_Acid_Biosynthetic_Process	Human	Lung	rep_2	7.8e-07
CYP1A2	GOBP_Icosanoid_Metabolic_Process	Human	Lung	rep_2	4.6e-07
CYP1A2	GOBP_Lipid_Catabolic_Process	Human	Lung	rep_2	1.4e-09
CYP1A2	GOBP_Regulation_Of_Hormone_Levels	Human	Lung	rep_2	1.6e-07

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CYP1A2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CYP1A2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CYP1A2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CYP1A2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CYP1A2	P05177	DB00951	Isoniazid	Cytochrome P450 1A2	SmallMoleculeDrug	approved\|investigational
CYP1A2	P05177	DB09061	Cannabidiol	Cytochrome P450 1A2	SmallMoleculeDrug	approved\|investigational
CYP1A2	P05177	DB11994	Diacerein	Cytochrome P450 1A2	SmallMoleculeDrug	approved\|investigational

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Related Diseases for CYP1A2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CYP1A2	C0019207	Hepatoma, Morris	2	CTD_human
CYP1A2	C0019208	Hepatoma, Novikoff	2	CTD_human
CYP1A2	C0023904	Liver Neoplasms, Experimental	2	CTD_human
CYP1A2	C0086404	Experimental Hepatoma	2	CTD_human
CYP1A2	C0007137	Squamous cell carcinoma	1	CTD_human
CYP1A2	C0008370	Cholestasis	1	CTD_human
CYP1A2	C0009402	Colorectal Carcinoma	1	CTD_human
CYP1A2	C0009404	Colorectal Neoplasms	1	CTD_human
CYP1A2	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	1	CTD_human
CYP1A2	C0011999	Diastematomyelia	1	CTD_human
CYP1A2	C0013221	Drug toxicity	1	CTD_human
CYP1A2	C0018273	Growth Disorders	1	CTD_human
CYP1A2	C0019193	Hepatitis, Toxic	1	CTD_human
CYP1A2	C0019209	Hepatomegaly	1	CTD_human
CYP1A2	C0023452	Childhood Acute Lymphoblastic Leukemia	1	CTD_human
CYP1A2	C0023453	L2 Acute Lymphoblastic Leukemia	1	CTD_human
CYP1A2	C0023890	Liver Cirrhosis	1	CTD_human
CYP1A2	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
CYP1A2	C0023895	Liver diseases	1	CTD_human
CYP1A2	C0024117	Chronic Obstructive Airway Disease	1	CTD_human
CYP1A2	C0024121	Lung Neoplasms	1	CTD_human
CYP1A2	C0025637	Methemoglobinemia	1	CTD_human
CYP1A2	C0027794	Neural Tube Defects	1	CTD_human
CYP1A2	C0027806	Neurenteric Cyst	1	CTD_human
CYP1A2	C0036341	Schizophrenia	1	PSYGENET
CYP1A2	C0037997	Splenic Diseases	1	CTD_human
CYP1A2	C0038002	Splenomegaly	1	CTD_human
CYP1A2	C0041755	Adverse reaction to drug	1	CTD_human
CYP1A2	C0080218	Tethered Cord Syndrome	1	CTD_human
CYP1A2	C0086565	Liver Dysfunction	1	CTD_human
CYP1A2	C0152234	Iniencephaly	1	CTD_human
CYP1A2	C0152426	Craniorachischisis	1	CTD_human
CYP1A2	C0162566	Porphyria Cutanea Tarda	1	CTD_human
CYP1A2	C0239946	Fibrosis, Liver	1	CTD_human
CYP1A2	C0242379	Malignant neoplasm of lung	1	CTD_human
CYP1A2	C0266453	Exencephaly	1	CTD_human
CYP1A2	C0273115	Lung Injury	1	CTD_human
CYP1A2	C0333641	Atrophic	1	CTD_human
CYP1A2	C0344479	Spinal Cord Myelodysplasia	1	CTD_human
CYP1A2	C0400966	Non-alcoholic Fatty Liver Disease	1	CTD_human
CYP1A2	C0702169	Acrania	1	CTD_human
CYP1A2	C0809983	Schizophrenia and related disorders	1	PSYGENET
CYP1A2	C0860207	Drug-Induced Liver Disease	1	CTD_human
CYP1A2	C1262760	Hepatitis, Drug-Induced	1	CTD_human
CYP1A2	C1527303	Chronic Airflow Obstruction	1	CTD_human
CYP1A2	C1961102	Precursor Cell Lymphoblastic Leukemia Lymphoma	1	CTD_human
CYP1A2	C2239176	Liver carcinoma	1	CTD_human
CYP1A2	C2350344	Chronic Lung Injury	1	CTD_human
CYP1A2	C3241937	Nonalcoholic Steatohepatitis	1	CTD_human
CYP1A2	C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
CYP1A2	C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
CYP1A2	C4279912	Chemically-Induced Liver Toxicity	1	CTD_human