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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CTSH (spascer ID:1512)

Gene summary for CTSH

Gene summary

Gene information
	Species	Human
	Gene symbol	CTSH
	Gene ID	1512
	Gene name	cathepsin H
	Synonyms	ACC-4\|ACC-5\|ACC4\|ACC5\|CPSB
	Cytomap	15q25.1
	Type of gene	protein-coding
	Description	pro-cathepsin HN-benzoylarginine-beta-naphthylamide hydrolasealeuraincathepsin B3cathepsin BA
	Modification date	20220513
	UniProtAcc	P09668

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CTSH	GO:0004197	cysteine-type endopeptidase activity	21873635	Function
CTSH	GO:0005615	extracellular space	21873635	Component
CTSH	GO:0005764	lysosome	21873635	Component
CTSH	GO:0051603	proteolysis involved in cellular protein catabolic process	21873635	Process

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Spatial pattern events for CTSH

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CTSH	Human	Brain	rep_1	33558695	5.52e-15
CTSH	Human	Brain	rep_3	33558695	4.93e-15
CTSH	Human	Brain	rep_4	33558695	6.08e-15
CTSH	Human	Brain	rep_9	33558695	3.01e-15
CTSH	Human	Brain	rep_10	33558695	3.23e-15
CTSH	Human	Brain	rep_11	33558695	3.36e-15
CTSH	Human	Brain	rep_12	33558695	3.65e-15
CTSH	Human	Bladder	rep_2	34385456	6.29e-15
CTSH	Human	Bladder	rep_4	34385456	7.43e-06
CTSH	Human	Intestine	rep_colon1	34417225	1.95e-15
CTSH	Human	Intestine	rep_colon2	34417225	8.12e-16
CTSH	Human	Intestine	rep_colon3	34417225	1.01e-15
CTSH	Human	Intestine	rep_colon4	34417225	1.14e-15
CTSH	Human	Liver	rep_liver1	34417225	1.08e-15
CTSH	Human	Liver	rep_liver2	34417225	6.98e-16
CTSH	Human	Liver	rep_liver4	34417225	7.71e-16
CTSH	Human	Intestine	A2	33406409	2.47e-15
CTSH	Human	Intestine	A3	33406409	3.28e-14
CTSH	Human	Intestine	A4	33406409	7.35e-15
CTSH	Human	Intestine	A6	33406409	8.60e-14
CTSH	Human	Intestine	A7	33406409	3.32e-11
CTSH	Human	Intestine	A8	33406409	4.60e-14
CTSH	Human	Intestine	A9	33406409	5.42e-14
CTSH	Human	Uterus	rep_1	34857954	5.13e-10
CTSH	Human	Uterus	rep_2	34857954	2.55e-15
CTSH	Human	Uterus	rep_3	34857954	1.66e-15
CTSH	Human	Uterus	rep_4	34857954	1.82e-15
CTSH	Human	Breast	D3	34650042	1.07e-07
CTSH	Human	Breast	D4	34650042	2.04e-10
CTSH	Human	Breast	1142243F	34493872	2.30e-15
CTSH	Human	Breast	1160920F	34493872	1.48e-15
CTSH	Human	Breast	CID4465	34493872	7.83e-15
CTSH	Human	Breast	CID44971	34493872	1.76e-15
CTSH	Human	Breast	CID4535	34493872	6.37e-15
CTSH	Human	Skin	P2_rep1	32946785	5.41e-15
CTSH	Human	Skin	P2_rep2	32946785	5.48e-15
CTSH	Human	Skin	P2_rep3	32946785	5.90e-15
CTSH	Human	Skin	P5_rep2	32946785	1.42e-06
CTSH	Human	Skin	mel1_rep1	30154148	8.19e-14
CTSH	Human	Skin	mel1_rep2	30154148	2.14e-13
CTSH	Human	Lung	rep_1	35355018	6.17e-12
CTSH	Human	Lung	rep_2	35355018	2.37e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Bladder_rep_2_H&E
Bladder_rep_4_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A2_H&E
Intestine_A3_H&E
Intestine_A4_H&E
Intestine_A6_H&E
Intestine_A7_H&E
Intestine_A8_H&E
Intestine_A9_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_D3_H&E
Breast_D4_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Skin_P2_rep3_H&E
Skin_P5_rep2_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E

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Spatial pattern pathway has CTSH envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CTSH	GOBP_Adaptive_Immune_Response	Human	Brain	rep_1	8.1e-16
CTSH	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Brain	rep_1	8.1e-16
CTSH	GOBP_Cell_Killing	Human	Brain	rep_1	2.8e-23
CTSH	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
CTSH	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
CTSH	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
CTSH	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
CTSH	GOBP_Lymphocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
CTSH	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	2.8e-23
CTSH	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
CTSH	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Brain	rep_1	1.3e-60
CTSH	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Brain	rep_1	4.4e-07
CTSH	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
CTSH	GOBP_Positive_Regulation_Of_Locomotion	Human	Brain	rep_1	3.1e-68
CTSH	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
CTSH	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
CTSH	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
CTSH	GOBP_Positive_Regulation_Of_Proteolysis	Human	Brain	rep_1	1.2e-161
CTSH	GOBP_Protein_Maturation	Human	Brain	rep_1	1.3e-161
CTSH	GOBP_Protein_Processing	Human	Brain	rep_1	1.3e-161
CTSH	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Brain	rep_1	3.1e-68
CTSH	GOBP_Regulation_Of_Immune_Response	Human	Brain	rep_1	8.1e-16
CTSH	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
CTSH	GOBP_Regulation_Of_Proteolysis	Human	Brain	rep_1	4.4e-07
CTSH	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
CTSH	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Blood_Vessel_Morphogenesis	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
CTSH	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Regulation_Of_Peptidase_Activity	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Regulation_Of_Vasculature_Development	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
CTSH	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
CTSH	GOBP_Response_To_Hormone	Human	Brain	rep_10	2.8e-23
CTSH	GOBP_Response_To_Lipid	Human	Brain	rep_10	2.8e-23
CTSH	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
CTSH	GOBP_Response_To_Thyroid_Hormone	Human	Brain	rep_10	2.8e-23
CTSH	GOBP_Ameboidal_Type_Cell_Migration	Human	Bladder	rep_2	2.7e-06
CTSH	GOBP_Blood_Vessel_Morphogenesis	Human	Bladder	rep_2	9.4e-07
CTSH	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
CTSH	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Bladder	rep_2	1.6e-04
CTSH	GOBP_Regulation_Of_Vasculature_Development	Human	Bladder	rep_2	4.2e-09
CTSH	GOBP_Response_To_Retinoic_Acid	Human	Bladder	rep_2	1.8e-08
CTSH	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
CTSH	GOBP_Zymogen_Activation	Human	Bladder	rep_2	8.2e-04
CTSH	GOBP_Dichotomous_Subdivision_Of_An_Epithelial_Terminal_Unit	Human	Bladder	rep_4	1.7e-04
CTSH	GOBP_Adaptive_Immune_Response	Human	Liver	rep_1	2.3e-76
CTSH	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Liver	rep_1	2.3e-76
CTSH	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Blood_Vessel_Morphogenesis	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Cell_Killing	Human	Liver	rep_1	6.5e-65
CTSH	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
CTSH	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
CTSH	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
CTSH	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
CTSH	GOBP_Lymphocyte_Mediated_Immunity	Human	Liver	rep_1	2.3e-76
CTSH	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	1.0e-70
CTSH	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
CTSH	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Liver	rep_1	2.0e-49
CTSH	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Liver	rep_1	3.7e-85
CTSH	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
CTSH	GOBP_Positive_Regulation_Of_Locomotion	Human	Liver	rep_1	1.9e-71
CTSH	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
CTSH	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
CTSH	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
CTSH	GOBP_Positive_Regulation_Of_Proteolysis	Human	Liver	rep_1	2.0e-70
CTSH	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Protein_Maturation	Human	Liver	rep_1	4.6e-81
CTSH	GOBP_Protein_Processing	Human	Liver	rep_1	6.7e-84
CTSH	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
CTSH	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Liver	rep_1	1.0e-70
CTSH	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Liver	rep_1	1.9e-71
CTSH	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Regulation_Of_Immune_Response	Human	Liver	rep_1	2.3e-76
CTSH	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
CTSH	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
CTSH	GOBP_Regulation_Of_Peptidase_Activity	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Regulation_Of_Proteolysis	Human	Liver	rep_1	1.1e-67
CTSH	GOBP_Regulation_Of_Vasculature_Development	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
CTSH	GOBP_Response_To_Hormone	Human	Liver	rep_1	3.0e-55
CTSH	GOBP_Response_To_Lipid	Human	Liver	rep_1	3.0e-55
CTSH	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
CTSH	GOBP_Response_To_Thyroid_Hormone	Human	Liver	rep_1	3.0e-55
CTSH	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
CTSH	GOBP_Zymogen_Activation	Human	Liver	rep_1	7.7e-79
CTSH	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
CTSH	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	rep_colon2	2.9e-50
CTSH	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
CTSH	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
CTSH	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	rep_colon2	1.6e-21
CTSH	GOBP_Protein_Maturation	Human	Intestine	rep_colon2	7.9e-42
CTSH	GOBP_Protein_Processing	Human	Intestine	rep_colon2	1.2e-19
CTSH	GOBP_Adaptive_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
CTSH	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Intestine	rep_colon4	7.2e-20
CTSH	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
CTSH	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
CTSH	GOBP_Lymphocyte_Mediated_Immunity	Human	Intestine	rep_colon4	7.2e-20
CTSH	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	rep_colon4	6.4e-48
CTSH	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
CTSH	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
CTSH	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
CTSH	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	rep_colon4	9.0e-12
CTSH	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
CTSH	GOBP_Regulation_Of_Immune_Response	Human	Intestine	rep_colon4	7.2e-20
CTSH	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
CTSH	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
CTSH	GOBP_Regulation_Of_Peptidase_Activity	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Regulation_Of_Proteolysis	Human	Intestine	rep_colon4	1.2e-51
CTSH	GOBP_Regulation_Of_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
CTSH	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
CTSH	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
CTSH	GOBP_Positive_Regulation_Of_Locomotion	Human	Intestine	rep_liver2	1.0e-64
CTSH	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	rep_liver2	1.0e-64
CTSH	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
CTSH	GOBP_Response_To_Hormone	Human	Intestine	rep_liver2	3.7e-39
CTSH	GOBP_Response_To_Lipid	Human	Intestine	rep_liver2	3.7e-39
CTSH	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
CTSH	GOBP_Response_To_Thyroid_Hormone	Human	Intestine	rep_liver2	3.7e-39
CTSH	GOBP_Cell_Killing	Human	Intestine	rep_liver4	3.1e-11
CTSH	GOBP_Activation_Of_Cysteine_Type_Endopeptidase_Activity_Involved_In_Apoptotic_Process	Human	Intestine	A3	2.9e-13
CTSH	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	A3	4.7e-07
CTSH	GOBP_Branching_Morphogenesis_Of_An_Epithelial_Tube	Human	Intestine	A3	3.4e-13
CTSH	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
CTSH	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Intestine	A3	4.0e-14
CTSH	GOBP_Cell_Killing	Human	Intestine	A3	8.0e-07
CTSH	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
CTSH	GOBP_Cellular_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-12
CTSH	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Intestine	A3	8.7e-19
CTSH	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
CTSH	GOBP_Epithelial_Tube_Morphogenesis	Human	Intestine	A3	5.0e-10
CTSH	GOBP_Erk1_And_Erk2_Cascade	Human	Intestine	A3	2.6e-07
CTSH	GOBP_Exocytosis	Human	Intestine	A3	4.7e-10
CTSH	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
CTSH	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
CTSH	GOBP_Immune_Response_Regulating_Signaling_Pathway	Human	Intestine	A3	2.2e-11
CTSH	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
CTSH	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
CTSH	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
CTSH	GOBP_Mapk_Cascade	Human	Intestine	A3	1.1e-12
CTSH	GOBP_Membrane_Protein_Proteolysis	Human	Intestine	A3	2.9e-08
CTSH	GOBP_Metanephros_Development	Human	Intestine	A3	2.9e-08
CTSH	GOBP_Morphogenesis_Of_A_Branching_Structure	Human	Intestine	A3	2.3e-11
CTSH	GOBP_Morphogenesis_Of_An_Epithelium	Human	Intestine	A3	1.5e-09
CTSH	GOBP_Multicellular_Organismal_Homeostasis	Human	Intestine	A3	8.8e-08
CTSH	GOBP_Negative_Regulation_Of_Cell_Death	Human	Intestine	A3	5.8e-14
CTSH	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
CTSH	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
CTSH	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	3.5e-07
CTSH	GOBP_Positive_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Intestine	A3	3.1e-08
CTSH	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
CTSH	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Intestine	A3	3.7e-11
CTSH	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
CTSH	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
CTSH	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
CTSH	GOBP_Positive_Regulation_Of_Peptidase_Activity	Human	Intestine	A3	2.8e-12
CTSH	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
CTSH	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	A3	5.2e-21
CTSH	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
CTSH	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
CTSH	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Intestine	A3	4.8e-12
CTSH	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
CTSH	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Intestine	A3	1.1e-09
CTSH	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Intestine	A3	2.9e-10
CTSH	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
CTSH	GOBP_Regulation_Of_Immune_Response	Human	Intestine	A3	1.6e-12
CTSH	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
CTSH	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
CTSH	GOBP_Regulation_Of_Peptidase_Activity	Human	Intestine	A3	9.8e-13
CTSH	GOBP_Regulation_Of_Protein_Stability	Human	Intestine	A3	9.7e-11
CTSH	GOBP_Regulation_Of_Proteolysis	Human	Intestine	A3	9.5e-13
CTSH	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
CTSH	GOBP_Response_To_Lipid	Human	Intestine	A3	1.7e-09
CTSH	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
CTSH	GOBP_Secretion	Human	Intestine	A3	1.8e-13
CTSH	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
CTSH	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
CTSH	GOBP_Urogenital_System_Development	Human	Intestine	A3	2.6e-07
CTSH	GOBP_Adaptive_Immune_Response	Human	Intestine	A8	2.4e-10
CTSH	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Intestine	A8	1.3e-09
CTSH	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	A8	3.3e-08
CTSH	GOBP_Antigen_Processing_And_Presentation	Human	Intestine	A8	1.7e-13
CTSH	GOBP_Bradykinin_Catabolic_Process	Human	Intestine	A8	4.4e-12
CTSH	GOBP_Cellular_Response_To_Thyroid_Hormone_Stimulus	Human	Intestine	A8	3.4e-11
CTSH	GOBP_Chemical_Homeostasis	Human	Intestine	A8	1.3e-12
CTSH	GOBP_Chemical_Homeostasis_Within_A_Tissue	Human	Intestine	A8	2.4e-11
CTSH	GOBP_Epithelial_Tube_Branching_Involved_In_Lung_Morphogenesis	Human	Intestine	A8	2.9e-07
CTSH	GOBP_Myeloid_Leukocyte_Activation	Human	Intestine	A8	3.8e-18
CTSH	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Intestine	A8	8.5e-11
CTSH	GOBP_Peptide_Catabolic_Process	Human	Intestine	A8	3.8e-07
CTSH	GOBP_Positive_Regulation_Of_Epithelial_Cell_Migration	Human	Intestine	A8	5.3e-08
CTSH	GOBP_Positive_Regulation_Of_Locomotion	Human	Intestine	A8	9.7e-07
CTSH	GOBP_Protein_Maturation	Human	Intestine	A8	1.1e-12
CTSH	GOBP_Protein_Processing	Human	Intestine	A8	4.1e-18
CTSH	GOBP_Response_To_Hormone	Human	Intestine	A8	2.3e-13
CTSH	GOBP_Response_To_Retinoic_Acid	Human	Intestine	A8	2.7e-08
CTSH	GOBP_Response_To_Thyroid_Hormone	Human	Intestine	A8	4.9e-12
CTSH	GOBP_T_Cell_Mediated_Cytotoxicity	Human	Intestine	A8	1.5e-08
CTSH	GOBP_T_Cell_Mediated_Immunity	Human	Intestine	A8	3.7e-15
CTSH	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
CTSH	GOBP_Zymogen_Activation	Human	Intestine	A8	4.1e-11
CTSH	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Pancreas	PDAC-B-st1	1.2e-05
CTSH	GOBP_Lung_Morphogenesis	Human	Pancreas	PDAC-B-st1	3.4e-06
CTSH	GOBP_Metanephros_Development	Human	Pancreas	PDAC-B-st1	8.7e-05
CTSH	GOBP_Dichotomous_Subdivision_Of_An_Epithelial_Terminal_Unit	Human	Pancreas	PDAC-A-st2	1.7e-05
CTSH	GOBP_Adaptive_Immune_Response	Human	Uterus	rep_4	6.1e-31
CTSH	GOBP_Adaptive_Immune_Response_Based_On_Somatic_Recombination_Of_Immune_Receptors_Built_From_Immunoglobulin_Superfamily_Domains	Human	Uterus	rep_4	6.1e-31
CTSH	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
CTSH	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
CTSH	GOBP_Lymphocyte_Mediated_Immunity	Human	Uterus	rep_4	6.1e-31
CTSH	GOBP_Regulation_Of_Immune_Response	Human	Uterus	rep_4	6.1e-31
CTSH	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
CTSH	GOBP_Anatomical_Structure_Homeostasis	Human	Uterus	rep_1	8.8e-07
CTSH	GOBP_Multicellular_Organismal_Homeostasis	Human	Uterus	rep_1	2.0e-06
CTSH	GOBP_Chemical_Homeostasis_Within_A_Tissue	Human	Uterus	rep_25	7.8e-08
CTSH	GOBP_Dichotomous_Subdivision_Of_An_Epithelial_Terminal_Unit	Human	Uterus	rep_25	8.1e-12
CTSH	GOBP_Bradykinin_Catabolic_Process	Human	Uterus	rep_26	2.1e-07
CTSH	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Uterus	rep_26	1.5e-11
CTSH	GOBP_Cellular_Protein_Catabolic_Process	Human	Uterus	rep_26	8.2e-11
CTSH	GOBP_Exocytosis	Human	Uterus	rep_26	5.1e-10
CTSH	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
CTSH	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
CTSH	GOBP_Myeloid_Leukocyte_Activation	Human	Uterus	rep_26	1.4e-11
CTSH	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
CTSH	GOBP_Peptide_Catabolic_Process	Human	Uterus	rep_26	6.1e-07
CTSH	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
CTSH	GOBP_Protein_Destabilization	Human	Uterus	rep_26	2.2e-08
CTSH	GOBP_Regulation_Of_Epithelial_Cell_Migration	Human	Uterus	rep_26	2.7e-06
CTSH	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
CTSH	GOBP_Regulation_Of_Proteolysis	Human	Uterus	rep_26	2.1e-07
CTSH	GOBP_Respiratory_System_Development	Human	Uterus	rep_26	1.3e-07
CTSH	GOBP_Response_To_Retinoic_Acid	Human	Uterus	rep_26	3.0e-14
CTSH	GOBP_Response_To_Thyroid_Hormone	Human	Uterus	rep_26	2.6e-12
CTSH	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
CTSH	GOBP_Cell_Killing	Human	Uterus	rep_28	1.6e-06
CTSH	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Uterus	rep_28	8.7e-06
CTSH	GOBP_Erk1_And_Erk2_Cascade	Human	Uterus	rep_29	7.0e-08
CTSH	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
CTSH	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
CTSH	GOBP_Regulation_Of_Peptidase_Activity	Human	Uterus	rep_29	1.4e-10
CTSH	GOBP_Ameboidal_Type_Cell_Migration	Human	Breast	rep_1	6.7e-99
CTSH	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Breast	rep_1	1.9e-98
CTSH	GOBP_Animal_Organ_Morphogenesis	Human	Breast	rep_1	5.4e-25
CTSH	GOBP_Blood_Vessel_Morphogenesis	Human	Breast	rep_1	1.5e-106
CTSH	GOBP_Branching_Morphogenesis_Of_An_Epithelial_Tube	Human	Breast	rep_1	1.9e-33
CTSH	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
CTSH	GOBP_Chemical_Homeostasis	Human	Breast	rep_1	4.8e-18
CTSH	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
CTSH	GOBP_Epithelium_Development	Human	Breast	rep_1	2.0e-22
CTSH	GOBP_Exocytosis	Human	Breast	rep_1	2.8e-29
CTSH	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
CTSH	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
CTSH	GOBP_Membrane_Protein_Proteolysis	Human	Breast	rep_1	6.2e-110
CTSH	GOBP_Metanephros_Development	Human	Breast	rep_1	5.1e-07
CTSH	GOBP_Morphogenesis_Of_An_Epithelium	Human	Breast	rep_1	2.3e-18
CTSH	GOBP_Multicellular_Organismal_Homeostasis	Human	Breast	rep_1	1.5e-16
CTSH	GOBP_Myeloid_Leukocyte_Activation	Human	Breast	rep_1	2.2e-37
CTSH	GOBP_Peptide_Catabolic_Process	Human	Breast	rep_1	7.8e-42
CTSH	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	9.2e-11
CTSH	GOBP_Positive_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Breast	rep_1	3.7e-11
CTSH	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
CTSH	GOBP_Positive_Regulation_Of_Epithelial_Cell_Migration	Human	Breast	rep_1	1.3e-49
CTSH	GOBP_Positive_Regulation_Of_Gene_Expression	Human	Breast	rep_1	7.3e-07
CTSH	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
CTSH	GOBP_Positive_Regulation_Of_Locomotion	Human	Breast	rep_1	7.2e-115
CTSH	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
CTSH	GOBP_Positive_Regulation_Of_Peptidase_Activity	Human	Breast	rep_1	5.6e-24
CTSH	GOBP_Positive_Regulation_Of_Proteolysis	Human	Breast	rep_1	1.7e-07
CTSH	GOBP_Positive_Regulation_Of_Vasculature_Development	Human	Breast	rep_1	4.6e-40
CTSH	GOBP_Protein_Maturation	Human	Breast	rep_1	4.1e-23
CTSH	GOBP_Protein_Processing	Human	Breast	rep_1	4.4e-37
CTSH	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Human	Breast	rep_1	4.6e-22
CTSH	GOBP_Regulation_Of_Cellular_Component_Movement	Human	Breast	rep_1	5.5e-21
CTSH	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Breast	rep_1	3.8e-05
CTSH	GOBP_Regulation_Of_Epithelial_Cell_Migration	Human	Breast	rep_1	1.6e-54
CTSH	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
CTSH	GOBP_Regulation_Of_Peptidase_Activity	Human	Breast	rep_1	2.2e-33
CTSH	GOBP_Regulation_Of_Proteolysis	Human	Breast	rep_1	6.4e-05
CTSH	GOBP_Regulation_Of_Vasculature_Development	Human	Breast	rep_1	1.9e-30
CTSH	GOBP_Respiratory_System_Development	Human	Breast	rep_1	3.3e-47
CTSH	GOBP_Response_To_Thyroid_Hormone	Human	Breast	rep_1	1.3e-27
CTSH	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
CTSH	GOBP_Tissue_Migration	Human	Breast	rep_1	7.3e-113
CTSH	GOBP_Tissue_Morphogenesis	Human	Breast	rep_1	1.4e-30
CTSH	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
CTSH	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
CTSH	GOBP_Urogenital_System_Development	Human	Breast	rep_1	1.4e-52
CTSH	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
CTSH	GOBP_Zymogen_Activation	Human	Breast	rep_1	1.6e-17
CTSH	GOBP_Activation_Of_Cysteine_Type_Endopeptidase_Activity_Involved_In_Apoptotic_Process	Human	Breast	rep_5	4.6e-05
CTSH	GOBP_Bradykinin_Catabolic_Process	Human	Breast	rep_5	2.1e-32
CTSH	GOBP_Cellular_Protein_Catabolic_Process	Human	Breast	rep_5	4.4e-04
CTSH	GOBP_Cellular_Response_To_Hormone_Stimulus	Human	Breast	rep_5	9.6e-12
CTSH	GOBP_Chemical_Homeostasis_Within_A_Tissue	Human	Breast	rep_5	3.7e-08
CTSH	GOBP_Epithelial_Tube_Branching_Involved_In_Lung_Morphogenesis	Human	Breast	rep_5	4.0e-13
CTSH	GOBP_Mapk_Cascade	Human	Breast	rep_5	4.6e-17
CTSH	GOBP_Morphogenesis_Of_A_Branching_Structure	Human	Breast	rep_5	5.4e-11
CTSH	GOBP_Negative_Regulation_Of_Cell_Death	Human	Breast	rep_5	1.9e-07
CTSH	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
CTSH	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
CTSH	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
CTSH	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
CTSH	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
CTSH	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
CTSH	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
CTSH	GOBP_Response_To_Hormone	Human	Breast	rep_5	2.9e-13
CTSH	GOBP_Response_To_Lipid	Human	Breast	rep_5	1.6e-10
CTSH	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
CTSH	GOBP_Cellular_Amide_Metabolic_Process	Human	Breast	rep_6	5.6e-05
CTSH	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
CTSH	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
CTSH	GOBP_Peptide_Metabolic_Process	Human	Breast	rep_6	8.7e-05
CTSH	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
CTSH	GOBP_Protein_Destabilization	Human	Breast	rep_6	1.3e-05
CTSH	GOBP_Regulation_Of_Protein_Stability	Human	Breast	rep_6	1.6e-08
CTSH	GOBP_Tissue_Morphogenesis	Human	Skin	P2_rep1	2.9e-08
CTSH	GOBP_Dichotomous_Subdivision_Of_An_Epithelial_Terminal_Unit	Human	Skin	P2_rep2	8.1e-09
CTSH	GOBP_Urogenital_System_Development	Human	Skin	P5_rep1	2.2e-12
CTSH	GOBP_Regulation_Of_Epithelial_Cell_Migration	Human	Skin	P5_rep2	3.3e-09
CTSH	GOBP_Regulation_Of_Protein_Stability	Human	Skin	P5_rep2	5.8e-08
CTSH	GOBP_Epithelium_Development	Human	Skin	P9_rep3	4.2e-08
CTSH	GOBP_Cellular_Response_To_Thyroid_Hormone_Stimulus	Human	Skin	P10_rep1	1.8e-10
CTSH	GOBP_Response_To_Thyroid_Hormone	Human	Skin	P10_rep1	1.6e-15
CTSH	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Skin	P10_rep2	1.1e-22
CTSH	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
CTSH	GOBP_Cell_Killing	Human	Lung	rep_1	7.5e-18
CTSH	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Human	Lung	rep_1	7.3e-07
CTSH	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Lung	rep_1	9.0e-08
CTSH	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
CTSH	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
CTSH	GOBP_Regulation_Of_Peptidase_Activity	Human	Lung	rep_1	4.6e-11
CTSH	GOBP_Regulation_Of_Proteolysis	Human	Lung	rep_1	3.2e-08
CTSH	GOBP_Response_To_Lipid	Human	Lung	rep_1	1.8e-09
CTSH	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08
CTSH	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Lung	rep_2	8.0e-10
CTSH	GOBP_Immune_Response_Regulating_Signaling_Pathway	Human	Lung	rep_2	1.2e-08
CTSH	GOBP_Lymphocyte_Mediated_Immunity	Human	Lung	rep_2	3.7e-07
CTSH	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07
CTSH	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07

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CTSH function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CTSH function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CTSH envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CTSH

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CTSH

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CTSH	C0011854	Diabetes Mellitus, Insulin-Dependent	1	CTD_human
CTSH	C0023467	Leukemia, Myelocytic, Acute	1	CTD_human
CTSH	C0026998	Acute Myeloid Leukemia, M1	1	CTD_human
CTSH	C0027404	Narcolepsy	1	ORPHANET
CTSH	C0205734	Diabetes, Autoimmune	1	CTD_human
CTSH	C0342302	Brittle diabetes	1	CTD_human
CTSH	C0751362	Narcolepsy-Cataplexy Syndrome	1	ORPHANET
CTSH	C1879321	Acute Myeloid Leukemia (AML-M2)	1	CTD_human
CTSH	C3837958	Diabetes Mellitus, Ketosis-Prone	1	CTD_human
CTSH	C4554117	Diabetes Mellitus, Sudden-Onset	1	CTD_human