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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CTSD (spascer ID:1509)

Gene summary for CTSD

Gene summary

Gene information
	Species	Human
	Gene symbol	CTSD
	Gene ID	1509
	Gene name	cathepsin D
	Synonyms	CLN10\|CPSD\|HEL-S-130P
	Cytomap	11p15.5
	Type of gene	protein-coding
	Description	cathepsin Dceroid-lipofuscinosis, neuronal 10epididymis secretory sperm binding protein Li 130Plysosomal aspartyl peptidaselysosomal aspartyl protease
	Modification date	20220513
	UniProtAcc	P07339

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CTSD	GO:0005764	lysosome	21873635	Component

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Spatial pattern events for CTSD

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CTSD	Human	Brain	rep_1	33558695	5.52e-15
CTSD	Human	Brain	rep_2	33558695	5.54e-15
CTSD	Human	Brain	rep_3	33558695	4.93e-15
CTSD	Human	Brain	rep_4	33558695	6.08e-15
CTSD	Human	Brain	rep_5	33558695	1.16e-14
CTSD	Human	Brain	rep_6	33558695	3.39e-14
CTSD	Human	Brain	rep_7	33558695	1.03e-14
CTSD	Human	Brain	rep_8	33558695	1.14e-14
CTSD	Human	Brain	rep_9	33558695	5.33e-15
CTSD	Human	Brain	rep_10	33558695	3.23e-15
CTSD	Human	Brain	rep_11	33558695	6.00e-15
CTSD	Human	Brain	rep_12	33558695	3.65e-15
CTSD	Human	Prostate	rep_4	29925878	2.13e-07
CTSD	Human	Liver	rep_1	34792289	8.34e-07
CTSD	Human	Intestine	rep_colon1	34417225	1.95e-15
CTSD	Human	Intestine	rep_colon2	34417225	8.12e-16
CTSD	Human	Intestine	rep_colon3	34417225	1.01e-15
CTSD	Human	Intestine	rep_colon4	34417225	1.14e-15
CTSD	Human	Liver	rep_liver1	34417225	1.08e-15
CTSD	Human	Liver	rep_liver2	34417225	1.27e-15
CTSD	Human	Liver	rep_liver3	34417225	3.51e-15
CTSD	Human	Liver	rep_liver4	34417225	7.71e-16
CTSD	Human	Intestine	A1	33406409	2.09e-15
CTSD	Human	Intestine	A2	33406409	2.47e-15
CTSD	Human	Intestine	A3	33406409	1.94e-14
CTSD	Human	Intestine	A4	33406409	7.35e-15
CTSD	Human	Intestine	A6	33406409	8.60e-14
CTSD	Human	Intestine	A7	33406409	1.45e-13
CTSD	Human	Intestine	A8	33406409	1.79e-13
CTSD	Human	Intestine	A9	33406409	6.22e-08
CTSD	Human	Pancreas	PDAC-D-st1	31932730	1.73e-07
CTSD	Human	Uterus	rep_1	34857954	1.12e-08
CTSD	Human	Uterus	rep_2	34857954	2.55e-15
CTSD	Human	Uterus	rep_3	34857954	1.66e-15
CTSD	Human	Breast	A1	34650042	4.03e-11
CTSD	Human	Breast	A2	34650042	1.13e-06
CTSD	Human	Breast	A3	34650042	3.79e-06
CTSD	Human	Breast	A5	34650042	8.97e-07
CTSD	Human	Breast	A6	34650042	6.35e-10
CTSD	Human	Breast	B1	34650042	1.27e-10
CTSD	Human	Breast	B2	34650042	3.25e-08
CTSD	Human	Breast	B3	34650042	4.25e-13
CTSD	Human	Breast	B5	34650042	7.65e-11
CTSD	Human	Breast	C1	34650042	1.93e-06
CTSD	Human	Breast	C2	34650042	1.83e-12
CTSD	Human	Breast	C3	34650042	5.60e-07
CTSD	Human	Breast	C4	34650042	4.93e-13
CTSD	Human	Breast	D1	34650042	8.62e-13
CTSD	Human	Breast	D2	34650042	1.06e-13
CTSD	Human	Breast	D3	34650042	1.04e-13
CTSD	Human	Breast	D4	34650042	8.06e-14
CTSD	Human	Breast	D5	34650042	1.07e-13
CTSD	Human	Breast	D6	34650042	1.01e-13
CTSD	Human	Breast	E1	34650042	1.81e-14
CTSD	Human	Breast	E2	34650042	2.12e-14
CTSD	Human	Breast	E3	34650042	1.82e-14
CTSD	Human	Breast	F1	34650042	2.96e-07
CTSD	Human	Breast	F2	34650042	7.64e-14
CTSD	Human	Breast	F3	34650042	5.68e-14
CTSD	Human	Breast	G2	34650042	1.28e-11
CTSD	Human	Breast	G3	34650042	1.26e-11
CTSD	Human	Breast	1142243F	34493872	2.30e-15
CTSD	Human	Breast	1160920F	34493872	1.48e-15
CTSD	Human	Breast	CID4290	34493872	4.68e-15
CTSD	Human	Breast	CID4465	34493872	4.85e-15
CTSD	Human	Breast	CID44971	34493872	1.76e-15
CTSD	Human	Breast	CID4535	34493872	6.37e-15
CTSD	Human	Heart	w9_s5	31835037	1.88e-03
CTSD	Human	Skin	P2_rep1	32946785	8.65e-15
CTSD	Human	Skin	P2_rep2	32946785	5.48e-15
CTSD	Human	Skin	P2_rep3	32946785	9.21e-15
CTSD	Human	Skin	P5_rep2	32946785	2.55e-14
CTSD	Human	Skin	P5_rep3	32946785	1.93e-14
CTSD	Human	Skin	mel2_rep1	30154148	3.26e-07
CTSD	Human	Skin	mel2_rep2	30154148	2.56e-14
CTSD	Human	Lung	rep_1	35355018	4.99e-15
CTSD	Human	Lung	rep_2	35355018	1.83e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_7_H&E
Brain_rep_8_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Brain_rep_11_H&E
Brain_rep_12_H&E
Liver_rep_1_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A3_H&E
Intestine_A4_H&E
Intestine_A6_H&E
Intestine_A7_H&E
Intestine_A8_H&E
Intestine_A9_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_A1_H&E
Breast_A2_H&E
Breast_A3_H&E
Breast_A5_H&E
Breast_A6_H&E
Breast_B1_H&E
Breast_B2_H&E
Breast_B3_H&E
Breast_B5_H&E
Breast_C1_H&E
Breast_C2_H&E
Breast_C3_H&E
Breast_C4_H&E
Breast_D1_H&E
Breast_D2_H&E
Breast_D3_H&E
Breast_D4_H&E
Breast_D5_H&E
Breast_D6_H&E
Breast_E1_H&E
Breast_E2_H&E
Breast_E3_H&E
Breast_F1_H&E
Breast_F2_H&E
Breast_F3_H&E
Breast_G2_H&E
Breast_G3_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E
Breast_CID4535_H&E
Skin_P2_rep3_H&E
Skin_P5_rep2_H&E
Skin_P5_rep3_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E

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Spatial pattern pathway has CTSD envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CTSD	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
CTSD	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
CTSD	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	2.8e-23
CTSD	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
CTSD	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
CTSD	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
CTSD	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
CTSD	GOBP_Positive_Regulation_Of_Proteolysis	Human	Brain	rep_1	1.2e-161
CTSD	GOBP_Regulation_Of_Proteolysis	Human	Brain	rep_1	4.4e-07
CTSD	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
CTSD	GOBP_Proteolysis	Human	Brain	rep_4	1.6e-22
CTSD	GOBP_Regulation_Of_Peptidase_Activity	Human	Brain	rep_4	4.1e-17
CTSD	GOBP_Regulation_Of_Protein_Localization	Human	Brain	rep_4	1.0e-14
CTSD	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
CTSD	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
CTSD	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	1.0e-70
CTSD	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
CTSD	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
CTSD	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
CTSD	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
CTSD	GOBP_Positive_Regulation_Of_Proteolysis	Human	Liver	rep_1	2.0e-70
CTSD	GOBP_Proteolysis	Human	Liver	rep_1	4.2e-73
CTSD	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
CTSD	GOBP_Regulation_Of_Peptidase_Activity	Human	Liver	rep_1	6.0e-76
CTSD	GOBP_Regulation_Of_Protein_Localization	Human	Liver	rep_1	2.1e-52
CTSD	GOBP_Regulation_Of_Proteolysis	Human	Liver	rep_1	1.1e-67
CTSD	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
CTSD	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
CTSD	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
CTSD	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	rep_colon2	1.6e-21
CTSD	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	rep_colon2	1.5e-57
CTSD	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
CTSD	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
CTSD	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
CTSD	GOBP_Proteolysis	Human	Intestine	rep_colon4	2.4e-90
CTSD	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
CTSD	GOBP_Regulation_Of_Peptidase_Activity	Human	Intestine	rep_colon4	1.9e-09
CTSD	GOBP_Regulation_Of_Proteolysis	Human	Intestine	rep_colon4	1.2e-51
CTSD	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
CTSD	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Intestine	A3	4.0e-14
CTSD	GOBP_Collagen_Catabolic_Process	Human	Intestine	A3	2.5e-08
CTSD	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
CTSD	GOBP_Exocytosis	Human	Intestine	A3	4.7e-10
CTSD	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
CTSD	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
CTSD	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
CTSD	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
CTSD	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
CTSD	GOBP_Positive_Regulation_Of_Cell_Death	Human	Intestine	A3	4.5e-11
CTSD	GOBP_Positive_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Intestine	A3	3.1e-08
CTSD	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
CTSD	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
CTSD	GOBP_Positive_Regulation_Of_Peptidase_Activity	Human	Intestine	A3	2.8e-12
CTSD	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
CTSD	GOBP_Positive_Regulation_Of_Proteolysis	Human	Intestine	A3	5.2e-21
CTSD	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
CTSD	GOBP_Proteolysis	Human	Intestine	A3	7.3e-12
CTSD	GOBP_Regulation_Of_Cell_Death	Human	Intestine	A3	7.1e-10
CTSD	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Intestine	A3	2.9e-10
CTSD	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
CTSD	GOBP_Regulation_Of_Peptidase_Activity	Human	Intestine	A3	9.8e-13
CTSD	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	A3	7.5e-08
CTSD	GOBP_Regulation_Of_Proteolysis	Human	Intestine	A3	9.5e-13
CTSD	GOBP_Secretion	Human	Intestine	A3	1.8e-13
CTSD	GOBP_Antigen_Processing_And_Presentation	Human	Intestine	A8	1.7e-13
CTSD	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen	Human	Intestine	A8	8.9e-10
CTSD	GOBP_Myeloid_Leukocyte_Activation	Human	Intestine	A8	3.8e-18
CTSD	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Intestine	A8	8.5e-11
CTSD	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Pancreas	PDAC-B-st1	7.1e-05
CTSD	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Pancreas	PDAC-B-st1	1.2e-05
CTSD	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
CTSD	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
CTSD	GOBP_Collagen_Catabolic_Process	Human	Uterus	rep_1	2.8e-07
CTSD	GOBP_Collagen_Metabolic_Process	Human	Uterus	rep_1	6.8e-06
CTSD	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Uterus	rep_26	7.6e-06
CTSD	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Uterus	rep_26	1.5e-11
CTSD	GOBP_Exocytosis	Human	Uterus	rep_26	5.1e-10
CTSD	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
CTSD	GOBP_Myeloid_Leukocyte_Activation	Human	Uterus	rep_26	1.4e-11
CTSD	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
CTSD	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
CTSD	GOBP_Regulation_Of_Proteolysis	Human	Uterus	rep_26	2.1e-07
CTSD	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen	Human	Uterus	rep_28	2.7e-08
CTSD	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
CTSD	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Uterus	rep_28	8.7e-06
CTSD	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
CTSD	GOBP_Regulation_Of_Peptidase_Activity	Human	Uterus	rep_29	1.4e-10
CTSD	GOBP_Collagen_Catabolic_Process	Human	Breast	rep_1	3.3e-18
CTSD	GOBP_Collagen_Metabolic_Process	Human	Breast	rep_1	1.8e-27
CTSD	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
CTSD	GOBP_Exocytosis	Human	Breast	rep_1	2.8e-29
CTSD	GOBP_Lipoprotein_Catabolic_Process	Human	Breast	rep_1	9.1e-23
CTSD	GOBP_Myeloid_Leukocyte_Activation	Human	Breast	rep_1	2.2e-37
CTSD	GOBP_Positive_Regulation_Of_Cell_Death	Human	Breast	rep_1	2.2e-15
CTSD	GOBP_Positive_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Breast	rep_1	3.7e-11
CTSD	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
CTSD	GOBP_Positive_Regulation_Of_Peptidase_Activity	Human	Breast	rep_1	5.6e-24
CTSD	GOBP_Positive_Regulation_Of_Proteolysis	Human	Breast	rep_1	1.7e-07
CTSD	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Breast	rep_1	3.8e-05
CTSD	GOBP_Regulation_Of_Peptidase_Activity	Human	Breast	rep_1	2.2e-33
CTSD	GOBP_Regulation_Of_Protein_Localization	Human	Breast	rep_1	2.8e-21
CTSD	GOBP_Regulation_Of_Proteolysis	Human	Breast	rep_1	6.4e-05
CTSD	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
CTSD	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
CTSD	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
CTSD	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
CTSD	GOBP_Proteolysis	Human	Breast	rep_5	1.8e-07
CTSD	GOBP_Regulation_Of_Cell_Death	Human	Breast	rep_5	9.8e-08
CTSD	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
CTSD	GOBP_Lipoprotein_Metabolic_Process	Human	Breast	rep_6	1.4e-05
CTSD	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
CTSD	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
CTSD	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
CTSD	GOBP_Lipoprotein_Catabolic_Process	Human	Skin	P9_rep3	1.7e-09
CTSD	GOBP_Collagen_Metabolic_Process	Human	Skin	P10_rep1	6.6e-15
CTSD	GOBP_Collagen_Catabolic_Process	Human	Skin	P10_rep2	5.8e-09
CTSD	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Skin	P10_rep2	1.1e-22
CTSD	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
CTSD	GOBP_Collagen_Catabolic_Process	Human	Lung	rep_1	3.5e-07
CTSD	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Human	Lung	rep_1	9.0e-08
CTSD	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
CTSD	GOBP_Regulation_Of_Peptidase_Activity	Human	Lung	rep_1	4.6e-11
CTSD	GOBP_Regulation_Of_Proteolysis	Human	Lung	rep_1	3.2e-08
CTSD	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Lung	rep_2	1.2e-07
CTSD	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Lung	rep_2	8.0e-10
CTSD	GOBP_Positive_Regulation_Of_Cell_Death	Human	Lung	rep_2	3.0e-07
CTSD	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07

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CTSD function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CTSD function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CTSD envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CTSD

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
CTSD	P07339	DB00071	Insulin pork	Cathepsin D	BiotechDrug	approved

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Related Diseases for CTSD

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CTSD	C1864669	NEURONAL CEROID LIPOFUSCINOSIS DUE TO CATHEPSIN D DEFICIENCY	4	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
CTSD	C0003873	Rheumatoid Arthritis	1	CTD_human
CTSD	C0007134	Renal Cell Carcinoma	1	CTD_human
CTSD	C0022658	Kidney Diseases	1	CTD_human
CTSD	C0027626	Neoplasm Invasiveness	1	CTD_human
CTSD	C0029408	Degenerative polyarthritis	1	CTD_human
CTSD	C0033578	Prostatic Neoplasms	1	CTD_human
CTSD	C0043094	Weight Gain	1	CTD_human
CTSD	C0086743	Osteoarthrosis Deformans	1	CTD_human
CTSD	C0279702	Conventional (Clear Cell) Renal Cell Carcinoma	1	CTD_human
CTSD	C0376358	Malignant neoplasm of prostate	1	CTD_human
CTSD	C1266042	Chromophobe Renal Cell Carcinoma	1	CTD_human
CTSD	C1266043	Sarcomatoid Renal Cell Carcinoma	1	CTD_human
CTSD	C1266044	Collecting Duct Carcinoma of the Kidney	1	CTD_human
CTSD	C1306837	Papillary Renal Cell Carcinoma	1	CTD_human
CTSD	C1862939	AMYOTROPHIC LATERAL SCLEROSIS 1	1	CTD_human
CTSD	C1862941	Amyotrophic Lateral Sclerosis, Sporadic	1	CTD_human
CTSD	C2239176	Liver carcinoma	1	CTD_human
CTSD	C4551993	Amyotrophic Lateral Sclerosis, Familial	1	CTD_human