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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CTBP1 (spascer ID:1487)

Gene summary for CTBP1

Gene summary

Gene information
	Species	Human
	Gene symbol	CTBP1
	Gene ID	1487
	Gene name	C-terminal binding protein 1
	Synonyms	BARS\|HADDTS
	Cytomap	4p16.3
	Type of gene	protein-coding
	Description	C-terminal-binding protein 1brefeldin A-ribosylated substrate
	Modification date	20220513
	UniProtAcc	Q13363

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for CTBP1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CTBP1	Human	Brain	rep_10	33558695	1.42e-06
CTBP1	Human	Intestine	rep_colon1	34417225	1.95e-15
CTBP1	Human	Intestine	rep_colon2	34417225	1.54e-11
CTBP1	Human	Intestine	rep_colon3	34417225	5.08e-14
CTBP1	Human	Liver	rep_liver1	34417225	1.08e-15
CTBP1	Human	Liver	rep_liver2	34417225	6.98e-16
CTBP1	Human	Liver	rep_liver4	34417225	1.39e-15
CTBP1	Human	Uterus	rep_1	34857954	5.13e-15
CTBP1	Human	Uterus	rep_2	34857954	1.32e-10
CTBP1	Human	Uterus	rep_3	34857954	1.66e-15
CTBP1	Human	Uterus	rep_4	34857954	1.30e-06
CTBP1	Human	Breast	1160920F	34493872	8.31e-08
CTBP1	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_10_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has CTBP1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CTBP1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	7.4e-34
CTBP1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
CTBP1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	2.8e-23
CTBP1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
CTBP1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.0e-70
CTBP1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
CTBP1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
CTBP1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
CTBP1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
CTBP1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
CTBP1	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
CTBP1	GOBP_Chromatin_Organization	Human	Intestine	A3	3.2e-11
CTBP1	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
CTBP1	GOBP_Histone_Deacetylation	Human	Intestine	A3	7.0e-09
CTBP1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Intestine	A3	5.9e-17
CTBP1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Intestine	A3	5.4e-19
CTBP1	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	9.1e-10
CTBP1	GOBP_Negative_Regulation_Of_Chromatin_Organization	Human	Intestine	A3	5.5e-24
CTBP1	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Intestine	A3	2.8e-18
CTBP1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.7e-14
CTBP1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	7.8e-11
CTBP1	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	3.2e-14
CTBP1	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	1.9e-15
CTBP1	GOBP_Peptidyl_Amino_Acid_Modification	Human	Intestine	A3	2.7e-09
CTBP1	GOBP_Peptidyl_Lysine_Modification	Human	Intestine	A3	2.8e-09
CTBP1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
CTBP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.7e-13
CTBP1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
CTBP1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	9.1e-12
CTBP1	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
CTBP1	GOBP_Regulation_Of_Chromosome_Organization	Human	Intestine	A3	3.2e-08
CTBP1	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
CTBP1	GOBP_Regulation_Of_Protein_Acetylation	Human	Intestine	A3	4.5e-08
CTBP1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
CTBP1	GOBP_Viral_Genome_Replication	Human	Intestine	A3	2.4e-08
CTBP1	GOBP_Viral_Life_Cycle	Human	Intestine	A3	1.1e-12
CTBP1	GOBP_Fat_Cell_Differentiation	Human	Intestine	A8	2.4e-24
CTBP1	GOBP_Negative_Regulation_Of_Histone_Acetylation	Human	Intestine	A8	1.9e-10
CTBP1	GOBP_Negative_Regulation_Of_Histone_H4_Acetylation	Human	Intestine	A8	5.5e-12
CTBP1	GOBP_Negative_Regulation_Of_Histone_Modification	Human	Intestine	A8	1.3e-12
CTBP1	GOBP_Negative_Regulation_Of_Peptidyl_Lysine_Acetylation	Human	Intestine	A8	1.2e-07
CTBP1	GOBP_Negative_Regulation_Of_Protein_Acetylation	Human	Intestine	A8	1.6e-13
CTBP1	GOBP_Peptidyl_Lysine_Acetylation	Human	Intestine	A8	1.9e-08
CTBP1	GOBP_Positive_Regulation_Of_Chromatin_Organization	Human	Intestine	A8	2.4e-13
CTBP1	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Intestine	A8	9.0e-07
CTBP1	GOBP_Positive_Regulation_Of_Histone_Deacetylation	Human	Intestine	A8	2.3e-18
CTBP1	GOBP_Protein_Acetylation	Human	Intestine	A8	6.7e-07
CTBP1	GOBP_Regulation_Of_Chromatin_Organization	Human	Intestine	A8	5.8e-15
CTBP1	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Human	Intestine	A8	7.4e-16
CTBP1	GOBP_Regulation_Of_Histone_Deacetylation	Human	Intestine	A8	2.4e-09
CTBP1	GOBP_Regulation_Of_Histone_H4_Acetylation	Human	Intestine	A8	1.7e-15
CTBP1	GOBP_Regulation_Of_Protein_Deacetylation	Human	Intestine	A8	4.9e-10
CTBP1	GOBP_White_Fat_Cell_Differentiation	Human	Intestine	A8	8.3e-15
CTBP1	GOBP_Regulation_Of_Chromatin_Organization	Human	Pancreas	PDAC-B-st1	2.6e-05
CTBP1	GOBP_Negative_Regulation_Of_Histone_Acetylation	Human	Pancreas	PDAC-A-st2	1.4e-05
CTBP1	GOBP_Negative_Regulation_Of_Peptidyl_Lysine_Acetylation	Human	Pancreas	PDAC-A-st2	9.4e-05
CTBP1	GOBP_Chromatin_Organization	Human	Uterus	rep_1	1.9e-06
CTBP1	GOBP_Negative_Regulation_Of_Histone_H4_Acetylation	Human	Uterus	rep_25	4.0e-15
CTBP1	GOBP_Positive_Regulation_Of_Chromatin_Organization	Human	Uterus	rep_25	1.3e-16
CTBP1	GOBP_Viral_Genome_Replication	Human	Uterus	rep_25	1.3e-17
CTBP1	GOBP_White_Fat_Cell_Differentiation	Human	Uterus	rep_25	2.4e-07
CTBP1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
CTBP1	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
CTBP1	GOBP_Fat_Cell_Differentiation	Human	Uterus	rep_26	3.8e-14
CTBP1	GOBP_Negative_Regulation_Of_Gene_Expression_Epigenetic	Human	Uterus	rep_26	1.9e-10
CTBP1	GOBP_Negative_Regulation_Of_Histone_Acetylation	Human	Uterus	rep_26	7.6e-09
CTBP1	GOBP_Negative_Regulation_Of_Histone_Modification	Human	Uterus	rep_26	2.1e-14
CTBP1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
CTBP1	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Human	Uterus	rep_26	2.3e-14
CTBP1	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Uterus	rep_26	6.2e-13
CTBP1	GOBP_Peptidyl_Lysine_Modification	Human	Uterus	rep_26	2.3e-09
CTBP1	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	1.7e-06
CTBP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Uterus	rep_26	1.2e-06
CTBP1	GOBP_Regulation_Of_Chromatin_Organization	Human	Uterus	rep_26	4.3e-07
CTBP1	GOBP_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	3.5e-08
CTBP1	GOBP_Regulation_Of_Gene_Expression_Epigenetic	Human	Uterus	rep_26	4.4e-12
CTBP1	GOBP_Regulation_Of_Histone_Modification	Human	Uterus	rep_26	2.9e-09
CTBP1	GOBP_Viral_Life_Cycle	Human	Uterus	rep_26	2.1e-06
CTBP1	GOBP_Histone_H4_Acetylation	Human	Uterus	rep_29	7.2e-08
CTBP1	GOBP_Peptidyl_Lysine_Acetylation	Human	Uterus	rep_29	6.7e-06
CTBP1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
CTBP1	GOBP_Fat_Cell_Differentiation	Human	Breast	rep_1	1.1e-26
CTBP1	GOBP_Histone_H4_Acetylation	Human	Breast	rep_1	1.2e-121
CTBP1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Human	Breast	rep_1	1.3e-54
CTBP1	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	7.3e-14
CTBP1	GOBP_Negative_Regulation_Of_Histone_Acetylation	Human	Breast	rep_1	2.5e-05
CTBP1	GOBP_Peptidyl_Lysine_Acetylation	Human	Breast	rep_1	4.3e-46
CTBP1	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
CTBP1	GOBP_Protein_Acetylation	Human	Breast	rep_1	3.7e-29
CTBP1	GOBP_Protein_Acylation	Human	Breast	rep_1	1.9e-23
CTBP1	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
CTBP1	GOBP_Viral_Genome_Replication	Human	Breast	rep_1	1.3e-07
CTBP1	GOBP_Viral_Life_Cycle	Human	Breast	rep_1	1.2e-08
CTBP1	GOBP_Negative_Regulation_Of_Chromatin_Organization	Human	Breast	rep_4	2.0e-15
CTBP1	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Breast	rep_5	5.3e-06
CTBP1	GOBP_Negative_Regulation_Of_Histone_H4_Acetylation	Human	Breast	rep_5	8.9e-12
CTBP1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	4.3e-05
CTBP1	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
CTBP1	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	3.0e-10
CTBP1	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
CTBP1	GOBP_Regulation_Of_Protein_Deacetylation	Human	Breast	rep_5	7.4e-04
CTBP1	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
CTBP1	GOBP_White_Fat_Cell_Differentiation	Human	Breast	rep_5	8.6e-04
CTBP1	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
CTBP1	GOBP_Chromatin_Organization	Human	Breast	rep_6	4.3e-07
CTBP1	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
CTBP1	GOBP_Histone_Deacetylation	Human	Breast	rep_6	1.3e-06
CTBP1	GOBP_Macromolecule_Deacylation	Human	Breast	rep_6	2.0e-04
CTBP1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Human	Breast	rep_6	2.6e-08
CTBP1	GOBP_Negative_Regulation_Of_Gene_Expression_Epigenetic	Human	Breast	rep_6	4.6e-06
CTBP1	GOBP_Negative_Regulation_Of_Histone_Modification	Human	Breast	rep_6	3.0e-06
CTBP1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	3.5e-08
CTBP1	GOBP_Negative_Regulation_Of_Peptidyl_Lysine_Acetylation	Human	Breast	rep_6	2.0e-04
CTBP1	GOBP_Negative_Regulation_Of_Protein_Acetylation	Human	Breast	rep_6	1.2e-05
CTBP1	GOBP_Negative_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_6	6.2e-08
CTBP1	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	8.2e-08
CTBP1	GOBP_Peptidyl_Amino_Acid_Modification	Human	Breast	rep_6	3.8e-05
CTBP1	GOBP_Peptidyl_Lysine_Modification	Human	Breast	rep_6	4.5e-08
CTBP1	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	1.4e-12
CTBP1	GOBP_Positive_Regulation_Of_Histone_Deacetylation	Human	Breast	rep_6	2.8e-04
CTBP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Breast	rep_6	7.3e-09
CTBP1	GOBP_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	3.0e-04
CTBP1	GOBP_Regulation_Of_Histone_Deacetylation	Human	Breast	rep_6	6.7e-04
CTBP1	GOBP_Regulation_Of_Peptidyl_Lysine_Acetylation	Human	Breast	rep_6	4.8e-06
CTBP1	GOBP_Regulation_Of_Protein_Acetylation	Human	Breast	rep_6	7.5e-05
CTBP1	GOBP_Negative_Regulation_Of_Histone_Modification	Human	Skin	P5_rep1	2.1e-09
CTBP1	GOBP_Peptidyl_Lysine_Acetylation	Human	Skin	P5_rep1	1.5e-08
CTBP1	GOBP_Macromolecule_Deacylation	Human	Skin	P5_rep3	6.7e-10
CTBP1	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Skin	P5_rep3	4.1e-08
CTBP1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
CTBP1	GOBP_Viral_Genome_Replication	Human	Skin	P9_rep2	2.5e-10
CTBP1	GOBP_Positive_Regulation_Of_Chromatin_Organization	Human	Skin	P10_rep2	2.7e-15
CTBP1	GOBP_Regulation_Of_Histone_Deacetylation	Human	Skin	P10_rep2	1.8e-15
CTBP1	GOBP_Regulation_Of_Histone_H4_Acetylation	Human	Skin	P10_rep2	9.9e-10
CTBP1	GOBP_White_Fat_Cell_Differentiation	Human	Skin	P10_rep2	6.0e-28
CTBP1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
CTBP1	GOBP_Viral_Genome_Replication	Human	Lung	rep_1	4.1e-08
CTBP1	GOBP_Viral_Life_Cycle	Human	Lung	rep_1	2.0e-16

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CTBP1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CTBP1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CTBP1 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
CTBP1	Uterus	proliferative	SOX9	ROR2,B3GLCT,RASA4B, etc.	0.455
CTBP1	Uterus	proliferative	Ciliated	ROR2,B3GLCT,RASA4B, etc.	0.25
CTBP1	Uterus	proliferative	SOX9_LGR5	ROR2,B3GLCT,RASA4B, etc.	0.291
CTBP1	Uterus	proliferative	SOX9_prolif	ROR2,B3GLCT,RASA4B, etc.	0.259

Motif information.

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Related Drugs for CTBP1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CTBP1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CTBP1	C4693578	HYPOTONIA, ATAXIA, DEVELOPMENTAL DELAY, AND TOOTH ENAMEL DEFECT SYNDROME	3	GENOMICS_ENGLAND;UNIPROT
CTBP1	C0009402	Colorectal Carcinoma	1	CTD_human
CTBP1	C0009404	Colorectal Neoplasms	1	CTD_human