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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: CSTF2 (spascer ID:1478)

Gene summary for CSTF2

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

CSTF2

Gene ID

1478

Gene namecleavage stimulation factor subunit 2
SynonymsCstF-64
CytomapXq22.1
Type of geneprotein-coding
Descriptioncleavage stimulation factor subunit 2CF-1 64 kDa subunitCSTF 64 kDa subunitcleavage stimulation factor 64 kDa subunitcleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDcleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
Modification date20220513
UniProtAcc

P33240


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
CSTF2

GO:0003729

mRNA binding

21873635

Function
CSTF2

GO:0005847

mRNA cleavage and polyadenylation specificity factor complex

21873635

Component
CSTF2

GO:0098789

pre-mRNA cleavage required for polyadenylation

21873635

Process

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Spatial pattern events for CSTF2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
CSTF2HumanLiverrep_liver1 344172251.08e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot


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Spatial pattern pathway has CSTF2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
CSTF2GOBP_Mrna_3_End_ProcessingHumanIntestineA3 4.9e-12
CSTF2GOBP_Mrna_Metabolic_ProcessHumanIntestineA3 7.7e-20
CSTF2GOBP_Mrna_ProcessingHumanIntestineA3 4.9e-17
CSTF2GOBP_Ncrna_Metabolic_ProcessHumanIntestineA3 8.6e-07
CSTF2GOBP_Nucleic_Acid_Phosphodiester_Bond_HydrolysisHumanIntestineA3 1.9e-08
CSTF2GOBP_Rna_3_End_ProcessingHumanIntestineA3 9.2e-07
CSTF2GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanIntestineA3 2.3e-07
CSTF2GOBP_Rna_ProcessingHumanIntestineA3 3.9e-09
CSTF2GOBP_Rna_SplicingHumanIntestineA3 3.3e-19
CSTF2GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanIntestineA3 2.2e-12
CSTF2GOBP_Trna_Metabolic_ProcessHumanIntestineA3 2.5e-12
CSTF2GOBP_Trna_ProcessingHumanIntestineA3 1.6e-08
CSTF2GOBP_Dna_Templated_Transcription_TerminationHumanIntestineA8 1.4e-07
CSTF2GOBP_Mrna_CleavageHumanIntestineA8 5.7e-07
CSTF2GOBP_Mrna_Cleavage_Involved_In_Mrna_ProcessingHumanIntestineA8 4.4e-07
CSTF2GOBP_Rna_PolyadenylationHumanIntestineA8 6.8e-07
CSTF2GOBP_Termination_Of_Rna_Polymerase_Ii_TranscriptionHumanIntestineA8 8.1e-26
CSTF2GOBP_Mrna_CleavageHumanPancreasPDAC-B-st1 7.7e-05
CSTF2GOBP_Mrna_Metabolic_ProcessHumanPancreasPDAC-B-st1 2.6e-05
CSTF2GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanPancreasPDAC-B-st1 3.3e-05
CSTF2GOBP_Rna_SplicingHumanPancreasPDAC-B-st1 1.9e-05
CSTF2GOBP_Dna_Templated_Transcription_TerminationHumanPancreasPDAC-A-st2 2.1e-07
CSTF2GOBP_Ncrna_ProcessingHumanUterusrep_1 4.5e-06
CSTF2GOBP_Mrna_Cleavage_Involved_In_Mrna_ProcessingHumanUterusrep_25 8.1e-09
CSTF2GOBP_Rna_SplicingHumanUterusrep_26 1.0e-05
CSTF2GOBP_Termination_Of_Rna_Polymerase_Ii_TranscriptionHumanUterusrep_26 4.2e-21
CSTF2GOBP_Trna_Metabolic_ProcessHumanUterusrep_26 9.4e-08
CSTF2GOBP_Mrna_3_End_ProcessingHumanUterusrep_27 5.1e-08
CSTF2GOBP_Rna_PolyadenylationHumanUterusrep_27 9.2e-09
CSTF2GOBP_Dna_Templated_Transcription_TerminationHumanBreastrep_6 7.8e-07
CSTF2GOBP_Mrna_3_End_ProcessingHumanBreastrep_6 6.6e-04
CSTF2GOBP_Mrna_CleavageHumanBreastrep_6 9.8e-11
CSTF2GOBP_Mrna_Cleavage_Involved_In_Mrna_ProcessingHumanBreastrep_6 1.0e-06
CSTF2GOBP_Mrna_Metabolic_ProcessHumanBreastrep_6 3.0e-08
CSTF2GOBP_Mrna_ProcessingHumanBreastrep_6 1.5e-06
CSTF2GOBP_Ncrna_Metabolic_ProcessHumanBreastrep_6 1.9e-04
CSTF2GOBP_Ncrna_ProcessingHumanBreastrep_6 1.3e-05
CSTF2GOBP_Nucleic_Acid_Phosphodiester_Bond_HydrolysisHumanBreastrep_6 2.6e-05
CSTF2GOBP_Rna_3_End_ProcessingHumanBreastrep_6 1.8e-05
CSTF2GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanBreastrep_6 2.8e-06
CSTF2GOBP_Rna_PolyadenylationHumanBreastrep_6 1.2e-05
CSTF2GOBP_Rna_ProcessingHumanBreastrep_6 3.5e-06
CSTF2GOBP_Rna_SplicingHumanBreastrep_6 1.1e-09
CSTF2GOBP_Rna_Splicing_Via_Endonucleolytic_Cleavage_And_LigationHumanBreastrep_6 2.6e-16
CSTF2GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanBreastrep_6 5.4e-08
CSTF2GOBP_Termination_Of_Rna_Polymerase_Ii_TranscriptionHumanBreastrep_6 1.7e-07
CSTF2GOBP_Trna_Metabolic_ProcessHumanBreastrep_6 3.9e-05
CSTF2GOBP_Trna_ProcessingHumanBreastrep_6 3.5e-08
CSTF2GOBP_Mrna_Metabolic_ProcessHumanSkinP5_rep3 1.8e-08
CSTF2GOBP_Mrna_ProcessingHumanSkinP5_rep3 9.7e-09
CSTF2GOBP_Rna_PolyadenylationHumanSkinP10_rep2 8.4e-15
CSTF2GOBP_Termination_Of_Rna_Polymerase_Ii_TranscriptionHumanSkinP10_rep2 7.6e-23
CSTF2GOBP_Rna_Phosphodiester_Bond_HydrolysisHumanLungrep_1 8.8e-08

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CSTF2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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CSTF2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for CSTF2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for CSTF2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CSTF2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource