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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: AMDHD1 (spascer ID:144193)

Gene summary for AMDHD1

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

AMDHD1

Gene ID

144193

Gene nameamidohydrolase domain containing 1
SynonymsHMFT1272
Cytomap12q23.1
Type of geneprotein-coding
Descriptionprobable imidazolonepropionaseamidohydrolase domain-containing protein 1
Modification date20220513
UniProtAcc

Q96NU7


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
AMDHD1

GO:0006548

histidine catabolic process

21873635

Process
AMDHD1

GO:0050480

imidazolonepropionase activity

21873635

Function

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Spatial pattern events for AMDHD1

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
AMDHD1HumanLiverrep_liver1 344172251.08e-15
AMDHD1HumanLiverrep_liver2 344172256.98e-16
AMDHD1HumanLiverrep_liver3 344172258.85e-11

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Liver_rep_liver3_H&E
boxplot

boxplot


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Spatial pattern pathway has AMDHD1 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
AMDHD1GOBP_Organonitrogen_Compound_Catabolic_ProcessHumanIntestineA3 4.5e-13
AMDHD1GOBP_Alpha_Amino_Acid_Metabolic_ProcessHumanIntestineA8 7.0e-13
AMDHD1GOBP_Cellular_Amino_Acid_Catabolic_ProcessHumanIntestineA8 2.5e-14
AMDHD1GOBP_Cellular_Amino_Acid_Metabolic_ProcessHumanIntestineA8 5.3e-13
AMDHD1GOBP_Dicarboxylic_Acid_Metabolic_ProcessHumanIntestineA8 2.6e-15
AMDHD1GOBP_Glutamine_Family_Amino_Acid_Metabolic_ProcessHumanIntestineA8 4.2e-08
AMDHD1GOBP_Histidine_Catabolic_ProcessHumanIntestineA8 1.8e-22
AMDHD1GOBP_Histidine_Metabolic_ProcessHumanIntestineA8 9.4e-11
AMDHD1GOBP_Monocarboxylic_Acid_Metabolic_ProcessHumanIntestineA8 7.3e-16
AMDHD1GOBP_Organic_Acid_Catabolic_ProcessHumanIntestineA8 1.6e-12
AMDHD1GOBP_Organic_Acid_Metabolic_ProcessHumanIntestineA8 2.5e-18
AMDHD1GOBP_Small_Molecule_Catabolic_ProcessHumanIntestineA8 2.2e-13
AMDHD1GOBP_Small_Molecule_Metabolic_ProcessHumanIntestineA8 2.1e-15
AMDHD1GOBP_Formate_Metabolic_ProcessHumanPancreasPDAC-B-st1 4.4e-10
AMDHD1GOBP_Cellular_Amino_Acid_Metabolic_ProcessHumanPancreasPDAC-A-st2 9.6e-05
AMDHD1GOBP_Glutamate_Metabolic_ProcessHumanUterusrep_25 3.2e-08
AMDHD1GOBP_Histidine_Metabolic_ProcessHumanUterusrep_25 5.1e-07
AMDHD1GOBP_Alpha_Amino_Acid_Metabolic_ProcessHumanUterusrep_26 1.6e-06
AMDHD1GOBP_Cellular_Amino_Acid_Catabolic_ProcessHumanUterusrep_26 3.2e-12
AMDHD1GOBP_Glutamine_Family_Amino_Acid_Metabolic_ProcessHumanUterusrep_26 5.2e-08
AMDHD1GOBP_Histidine_Catabolic_ProcessHumanUterusrep_26 1.5e-11
AMDHD1GOBP_Organic_Acid_Catabolic_ProcessHumanUterusrep_26 6.9e-09
AMDHD1GOBP_Organic_Acid_Metabolic_ProcessHumanUterusrep_26 4.9e-06
AMDHD1GOBP_Organonitrogen_Compound_Catabolic_ProcessHumanUterusrep_26 1.0e-08
AMDHD1GOBP_Small_Molecule_Catabolic_ProcessHumanUterusrep_26 9.1e-13
AMDHD1GOBP_Formate_Metabolic_ProcessHumanBreastrep_5 5.9e-19
AMDHD1GOBP_Glutamate_Metabolic_ProcessHumanBreastrep_5 3.1e-12
AMDHD1GOBP_Alpha_Amino_Acid_Metabolic_ProcessHumanBreastrep_6 1.7e-08
AMDHD1GOBP_Cellular_Amide_Metabolic_ProcessHumanBreastrep_6 5.6e-05
AMDHD1GOBP_Cellular_Amino_Acid_Catabolic_ProcessHumanBreastrep_6 1.6e-05
AMDHD1GOBP_Cellular_Amino_Acid_Metabolic_ProcessHumanBreastrep_6 1.0e-10
AMDHD1GOBP_Histidine_Metabolic_ProcessHumanBreastrep_6 2.2e-05
AMDHD1GOBP_Monocarboxylic_Acid_Metabolic_ProcessHumanBreastrep_6 6.1e-07
AMDHD1GOBP_Organic_Acid_Catabolic_ProcessHumanBreastrep_6 1.5e-11
AMDHD1GOBP_Organic_Acid_Metabolic_ProcessHumanBreastrep_6 6.7e-05
AMDHD1GOBP_Organonitrogen_Compound_Catabolic_ProcessHumanBreastrep_6 9.5e-06
AMDHD1GOBP_Small_Molecule_Catabolic_ProcessHumanBreastrep_6 4.7e-07
AMDHD1GOBP_Small_Molecule_Metabolic_ProcessHumanBreastrep_6 5.5e-09
AMDHD1GOBP_Histidine_Metabolic_ProcessHumanSkinP10_rep2 3.2e-10

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AMDHD1 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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AMDHD1 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for AMDHD1 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for AMDHD1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AMDHD1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource