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Spatial pattern gene: CSE1L (spascer ID:1434) |
Gene summary for CSE1L |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | CSE1L | Gene ID | 1434 |
| Gene name | chromosome segregation 1 like |
| Synonyms | CAS|CSE1|XPO2 |
| Cytomap | 20q13.13 |
| Type of gene | protein-coding |
| Description | exportin-2CSE1 chromosome segregation 1-likecellular apoptosis susceptibility proteinchromosome segregation 1-like proteinepididymis secretory sperm binding proteinexp2importin-alpha re-exporter |
| Modification date | 20220513 |
| UniProtAcc | P55060 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| CSE1L | GO:0005049 | nuclear export signal receptor activity | 21873635 | Function |
| CSE1L | GO:0005635 | nuclear envelope | 21873635 | Component |
| CSE1L | GO:0005829 | cytosol | 21873635 | Component |
| CSE1L | GO:0006606 | protein import into nucleus | 21873635 | Process |
| CSE1L | GO:0006611 | protein export from nucleus | 21873635 | Process |
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Spatial pattern events for CSE1L |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| CSE1L | Human | Bladder | rep_1 | 34385456 | 8.93e-15 |
| CSE1L | Human | Bladder | rep_2 | 34385456 | 6.47e-07 |
| CSE1L | Human | Intestine | rep_colon1 | 34417225 | 4.09e-14 |
| CSE1L | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| CSE1L | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| CSE1L | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| CSE1L | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| CSE1L | Human | Liver | rep_liver4 | 34417225 | 7.71e-16 |
| CSE1L | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| CSE1L | Human | Breast | 1160920F | 34493872 | 2.01e-14 |
| CSE1L | Human | Breast | CID44971 | 34493872 | 1.76e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Bladder_rep_1_H&E  |  |
Bladder_rep_2_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Liver_rep_liver4_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID44971_H&E  |  |
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Spatial pattern pathway has CSE1L envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| CSE1L | GOBP_Cellular_Macromolecule_Localization | Human | Intestine | A3 | 1.7e-09 |
| CSE1L | GOBP_Establishment_Of_Protein_Localization | Human | Intestine | A3 | 5.0e-10 |
| CSE1L | GOBP_Establishment_Of_Protein_Localization_To_Organelle | Human | Intestine | A3 | 3.8e-08 |
| CSE1L | GOBP_Intracellular_Protein_Transport | Human | Intestine | A3 | 4.8e-12 |
| CSE1L | GOBP_Intracellular_Transport | Human | Intestine | A3 | 7.6e-15 |
| CSE1L | GOBP_Nuclear_Export | Human | Intestine | A3 | 3.6e-07 |
| CSE1L | GOBP_Nuclear_Transport | Human | Intestine | A3 | 5.6e-10 |
| CSE1L | GOBP_Protein_Localization_To_Nucleus | Human | Intestine | A3 | 7.7e-09 |
| CSE1L | GOBP_Protein_Localization_To_Organelle | Human | Intestine | A3 | 1.5e-12 |
| CSE1L | GOBP_Nuclear_Export | Human | Uterus | rep_25 | 7.4e-11 |
| CSE1L | GOBP_Nuclear_Transport | Human | Uterus | rep_25 | 2.3e-13 |
| CSE1L | GOBP_Protein_Import | Human | Uterus | rep_26 | 5.4e-13 |
| CSE1L | GOBP_Cellular_Macromolecule_Localization | Human | Breast | rep_1 | 3.7e-09 |
| CSE1L | GOBP_Establishment_Of_Protein_Localization | Human | Breast | rep_1 | 7.2e-05 |
| CSE1L | GOBP_Protein_Localization_To_Nucleus | Human | Breast | rep_5 | 1.3e-04 |
| CSE1L | GOBP_Establishment_Of_Protein_Localization_To_Organelle | Human | Breast | rep_6 | 8.5e-11 |
| CSE1L | GOBP_Import_Into_Nucleus | Human | Breast | rep_6 | 4.5e-08 |
| CSE1L | GOBP_Intracellular_Protein_Transport | Human | Breast | rep_6 | 6.4e-12 |
| CSE1L | GOBP_Intracellular_Transport | Human | Breast | rep_6 | 1.3e-08 |
| CSE1L | GOBP_Nuclear_Export | Human | Breast | rep_6 | 1.4e-05 |
| CSE1L | GOBP_Nuclear_Transport | Human | Breast | rep_6 | 3.1e-08 |
| CSE1L | GOBP_Protein_Import | Human | Breast | rep_6 | 3.9e-08 |
| CSE1L | GOBP_Protein_Localization_To_Organelle | Human | Breast | rep_6 | 1.1e-07 |
| CSE1L | GOBP_Import_Into_Nucleus | Human | Skin | P5_rep1 | 3.8e-09 |
| CSE1L | GOBP_Nuclear_Transport | Human | Skin | P5_rep1 | 5.0e-19 |
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CSE1L function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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CSE1L function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for CSE1L envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for CSE1L |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CSE1L |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
