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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: CRYZ (spascer ID:1429)

Gene summary for CRYZ

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

CRYZ

Gene ID

1429

Gene namecrystallin zeta
Synonyms-
Cytomap1p31.1
Type of geneprotein-coding
Descriptionquinone oxidoreductaseNADPH:quinone reductasecrystallin, zeta (quinone reductase)epididymis secretory sperm binding protein
Modification date20220513
UniProtAcc

Q08257


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
CRYZ

GO:0003730

mRNA 3'-UTR binding

21873635

Function
CRYZ

GO:0003960

NADPH:quinone reductase activity

21873635

Function
CRYZ

GO:0005829

cytosol

21873635

Component
CRYZ

GO:0070402

NADPH binding

21873635

Function

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Spatial pattern events for CRYZ

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
CRYZHumanLiverrep_liver1 344172251.08e-15
CRYZHumanLiverrep_liver2 344172252.49e-15
CRYZHumanUterusrep_3 348579549.57e-06

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Uterus_rep_3_H&E
boxplot

boxplot


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Spatial pattern pathway has CRYZ envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
CRYZGOBP_Sensory_Perception_Of_Light_StimulusHumanBladderrep_2 3.7e-17
CRYZGOBP_Nervous_System_ProcessHumanIntestineA3 9.7e-07
CRYZGOBP_Response_To_Xenobiotic_StimulusHumanIntestineA3 2.5e-09
CRYZGOBP_Protein_HomotetramerizationHumanIntestineA8 2.6e-12
CRYZGOBP_Protein_TetramerizationHumanIntestineA8 2.0e-12
CRYZGOBP_Sensory_PerceptionHumanIntestineA8 2.1e-09
CRYZGOBP_Xenobiotic_Catabolic_ProcessHumanIntestineA8 1.6e-12
CRYZGOBP_Protein_Complex_OligomerizationHumanPancreasPDAC-B-st1 8.7e-05
CRYZGOBP_Protein_HomotetramerizationHumanUterusrep_1 5.6e-07
CRYZGOBP_Nervous_System_ProcessHumanUterusrep_26 2.3e-07
CRYZGOBP_Protein_TetramerizationHumanUterusrep_29 4.3e-07
CRYZGOBP_Nervous_System_ProcessHumanBreastrep_1 1.2e-04
CRYZGOBP_Protein_Complex_OligomerizationHumanBreastrep_1 1.7e-04
CRYZGOBP_Protein_HomotetramerizationHumanBreastrep_1 5.2e-07
CRYZGOBP_Sensory_Perception_Of_Light_StimulusHumanBreastrep_1 8.2e-37
CRYZGOBP_Xenobiotic_Catabolic_ProcessHumanBreastrep_1 1.2e-38
CRYZGOBP_Response_To_Xenobiotic_StimulusHumanBreastrep_5 2.9e-05
CRYZGOBP_Protein_HomooligomerizationHumanSkinP10_rep1 9.8e-09
CRYZGOBP_Xenobiotic_Catabolic_ProcessHumanSkinP10_rep2 2.2e-13

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CRYZ function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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CRYZ function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for CRYZ envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for CRYZ

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CRYZ

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource