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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: NEK7 (spascer ID:140609)

Gene summary for NEK7

Gene summary

Gene information
	Species	Human
	Gene symbol	NEK7
	Gene ID	140609
	Gene name	NIMA related kinase 7
	Synonyms	-
	Cytomap	1q31.3
	Type of gene	protein-coding
	Description	serine/threonine-protein kinase Nek7NIMA (never in mitosis gene a)-related kinase 7never in mitosis A-related kinase 7nimA-related protein kinase 7
	Modification date	20220513
	UniProtAcc	Q8TDX7

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for NEK7

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
NEK7	Human	Brain	rep_9	33558695	5.33e-15
NEK7	Human	Brain	rep_10	33558695	3.23e-15
NEK7	Human	Intestine	rep_colon2	34417225	2.52e-10
NEK7	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_9_H&E
Brain_rep_10_H&E
Intestine_rep_colon2_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has NEK7 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
NEK7	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
NEK7	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
NEK7	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
NEK7	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
NEK7	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
NEK7	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
NEK7	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
NEK7	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
NEK7	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
NEK7	GOBP_Dna_Biosynthetic_Process	Human	Intestine	A3	9.4e-13
NEK7	GOBP_Dna_Metabolic_Process	Human	Intestine	A3	1.2e-09
NEK7	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
NEK7	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
NEK7	GOBP_Microtubule_Cytoskeleton_Organization	Human	Intestine	A3	4.8e-11
NEK7	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
NEK7	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
NEK7	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
NEK7	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Intestine	A3	3.1e-07
NEK7	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
NEK7	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
NEK7	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.7e-13
NEK7	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Intestine	A3	2.1e-11
NEK7	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
NEK7	GOBP_Regulation_Of_Chromosome_Organization	Human	Intestine	A3	3.2e-08
NEK7	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Intestine	A3	2.8e-10
NEK7	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
NEK7	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
NEK7	GOBP_Regulation_Of_Telomere_Capping	Human	Intestine	A3	4.1e-12
NEK7	GOBP_Regulation_Of_Transferase_Activity	Human	Intestine	A3	3.9e-10
NEK7	GOBP_Spindle_Assembly	Human	Intestine	A3	6.2e-09
NEK7	GOBP_Spindle_Organization	Human	Intestine	A3	4.4e-08
NEK7	GOBP_Telomere_Capping	Human	Intestine	A3	6.9e-13
NEK7	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Intestine	A8	9.0e-07
NEK7	GOBP_Positive_Regulation_Of_Telomere_Capping	Human	Intestine	A8	5.9e-20
NEK7	GOBP_Regulation_Of_Dna_Biosynthetic_Process	Human	Intestine	A8	1.2e-08
NEK7	GOBP_Regulation_Of_Telomerase_Activity	Human	Intestine	A8	2.4e-08
NEK7	GOBP_Regulation_Of_Telomere_Capping	Human	Pancreas	PDAC-B-st1	3.8e-05
NEK7	GOBP_Spindle_Organization	Human	Pancreas	PDAC-B-st1	3.4e-05
NEK7	GOBP_Positive_Regulation_Of_Telomere_Maintenance_Via_Telomere_Lengthening	Human	Pancreas	PDAC-A-st2	3.3e-06
NEK7	GOBP_Regulation_Of_Telomere_Maintenance	Human	Pancreas	PDAC-A-st2	4.3e-06
NEK7	GOBP_Telomere_Capping	Human	Pancreas	PDAC-A-st2	1.6e-05
NEK7	GOBP_Anatomical_Structure_Homeostasis	Human	Uterus	rep_1	8.8e-07
NEK7	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
NEK7	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
NEK7	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	1.7e-06
NEK7	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Uterus	rep_26	2.8e-06
NEK7	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Uterus	rep_26	1.2e-06
NEK7	GOBP_Positive_Regulation_Of_Telomere_Maintenance	Human	Uterus	rep_26	1.3e-06
NEK7	GOBP_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	3.5e-08
NEK7	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Uterus	rep_26	2.1e-06
NEK7	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
NEK7	GOBP_Regulation_Of_Telomere_Maintenance	Human	Uterus	rep_26	5.3e-07
NEK7	GOBP_Spindle_Assembly	Human	Uterus	rep_26	8.1e-08
NEK7	GOBP_Spindle_Organization	Human	Uterus	rep_26	3.2e-06
NEK7	GOBP_Telomere_Capping	Human	Uterus	rep_26	3.2e-09
NEK7	GOBP_Regulation_Of_Telomere_Capping	Human	Uterus	rep_29	3.2e-07
NEK7	GOBP_Cytoskeleton_Organization	Human	Breast	rep_1	1.3e-22
NEK7	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
NEK7	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
NEK7	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
NEK7	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
NEK7	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
NEK7	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
NEK7	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
NEK7	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
NEK7	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
NEK7	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
NEK7	GOBP_Dna_Biosynthetic_Process	Human	Breast	rep_6	5.0e-13
NEK7	GOBP_Dna_Metabolic_Process	Human	Breast	rep_6	1.4e-10
NEK7	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
NEK7	GOBP_Microtubule_Cytoskeleton_Organization	Human	Breast	rep_6	1.9e-04
NEK7	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
NEK7	GOBP_Organelle_Assembly	Human	Breast	rep_6	2.3e-07
NEK7	GOBP_Positive_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	1.4e-12
NEK7	GOBP_Positive_Regulation_Of_Dna_Biosynthetic_Process	Human	Breast	rep_6	1.1e-07
NEK7	GOBP_Positive_Regulation_Of_Dna_Metabolic_Process	Human	Breast	rep_6	2.4e-08
NEK7	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Breast	rep_6	7.3e-09
NEK7	GOBP_Positive_Regulation_Of_Telomerase_Activity	Human	Breast	rep_6	9.3e-09
NEK7	GOBP_Positive_Regulation_Of_Telomere_Maintenance	Human	Breast	rep_6	4.4e-12
NEK7	GOBP_Positive_Regulation_Of_Telomere_Maintenance_Via_Telomere_Lengthening	Human	Breast	rep_6	1.2e-12
NEK7	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	3.2e-05
NEK7	GOBP_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	3.0e-04
NEK7	GOBP_Regulation_Of_Dna_Biosynthetic_Process	Human	Breast	rep_6	4.0e-08
NEK7	GOBP_Regulation_Of_Dna_Metabolic_Process	Human	Breast	rep_6	9.5e-08
NEK7	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
NEK7	GOBP_Regulation_Of_Telomerase_Activity	Human	Breast	rep_6	4.2e-07
NEK7	GOBP_Regulation_Of_Telomere_Maintenance	Human	Breast	rep_6	8.6e-07
NEK7	GOBP_Regulation_Of_Telomere_Maintenance_Via_Telomere_Lengthening	Human	Breast	rep_6	2.8e-09
NEK7	GOBP_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	4.6e-05
NEK7	GOBP_Rna_Dependent_Dna_Biosynthetic_Process	Human	Breast	rep_6	9.8e-09
NEK7	GOBP_Spindle_Assembly	Human	Breast	rep_6	2.6e-07
NEK7	GOBP_Spindle_Organization	Human	Breast	rep_6	2.9e-05
NEK7	GOBP_Telomere_Capping	Human	Breast	rep_6	7.3e-06
NEK7	GOBP_Telomere_Maintenance_Via_Telomere_Lengthening	Human	Breast	rep_6	8.1e-08
NEK7	GOBP_Telomere_Organization	Human	Breast	rep_6	6.0e-08
NEK7	GOBP_Positive_Regulation_Of_Telomere_Maintenance_Via_Telomere_Lengthening	Human	Skin	P2_rep2	1.0e-07
NEK7	GOBP_Regulation_Of_Telomere_Maintenance	Human	Skin	P2_rep2	2.3e-10
NEK7	GOBP_Regulation_Of_Telomere_Maintenance_Via_Telomere_Lengthening	Human	Skin	P2_rep2	3.9e-08
NEK7	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Skin	P5_rep3	4.1e-08
NEK7	GOBP_Positive_Regulation_Of_Telomerase_Activity	Human	Skin	P5_rep3	2.4e-08
NEK7	GOBP_Regulation_Of_Telomerase_Activity	Human	Skin	P5_rep3	1.4e-08
NEK7	GOBP_Telomere_Capping	Human	Skin	P5_rep3	3.5e-08
NEK7	GOBP_Cytoskeleton_Organization	Human	Skin	P9_rep3	3.1e-12
NEK7	GOBP_Positive_Regulation_Of_Telomere_Capping	Human	Skin	P10_rep2	4.6e-29
NEK7	GOBP_Regulation_Of_Telomere_Capping	Human	Skin	P10_rep2	4.5e-08

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NEK7 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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NEK7 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for NEK7 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for NEK7

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for NEK7

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
NEK7	C0043094	Weight Gain	1	CTD_human