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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: NDUFA11 (spascer ID:126328)

Gene summary for NDUFA11

Gene summary

Gene information
	Species	Human
	Gene symbol	NDUFA11
	Gene ID	126328
	Gene name	NADH:ubiquinone oxidoreductase subunit A11
	Synonyms	B14.7\|CI-B14.7\|MC1DN14
	Cytomap	19p13.3
	Type of gene	protein-coding
	Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDaNADH-ubiquinone oxidoreductase subunit B14.7complex I B14.7 subunit
	Modification date	20220513
	UniProtAcc	Q86Y39

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
NDUFA11	GO:0005747	mitochondrial respiratory chain complex I	21873635	Component

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Spatial pattern events for NDUFA11

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
NDUFA11	Human	Intestine	rep_colon1	34417225	3.42e-15
NDUFA11	Human	Intestine	rep_colon2	34417225	8.12e-16
NDUFA11	Human	Intestine	rep_colon3	34417225	1.01e-15
NDUFA11	Human	Intestine	rep_colon4	34417225	1.14e-15
NDUFA11	Human	Liver	rep_liver1	34417225	1.08e-15
NDUFA11	Human	Liver	rep_liver2	34417225	2.49e-15
NDUFA11	Human	Liver	rep_liver3	34417225	3.51e-15
NDUFA11	Human	Liver	rep_liver4	34417225	1.39e-15
NDUFA11	Human	Intestine	A1	33406409	2.09e-15
NDUFA11	Human	Intestine	A2	33406409	2.47e-15
NDUFA11	Human	Intestine	A4	33406409	7.35e-15
NDUFA11	Human	Uterus	rep_1	34857954	2.60e-07
NDUFA11	Human	Uterus	rep_2	34857954	2.55e-15
NDUFA11	Human	Uterus	rep_3	34857954	1.66e-15
NDUFA11	Human	Uterus	rep_4	34857954	1.82e-15
NDUFA11	Human	Breast	B1	34650042	6.28e-10
NDUFA11	Human	Breast	B4	34650042	1.27e-07
NDUFA11	Human	Breast	B5	34650042	2.19e-07
NDUFA11	Human	Breast	B6	34650042	7.29e-08
NDUFA11	Human	Breast	D4	34650042	6.51e-08
NDUFA11	Human	Breast	E2	34650042	1.95e-06
NDUFA11	Human	Breast	H1	34650042	7.06e-06
NDUFA11	Human	Breast	1142243F	34493872	1.18e-07
NDUFA11	Human	Breast	1160920F	34493872	1.48e-15
NDUFA11	Human	Breast	CID4465	34493872	7.37e-11
NDUFA11	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A4_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_B1_H&E
Breast_B4_H&E
Breast_B5_H&E
Breast_B6_H&E
Breast_D4_H&E
Breast_E2_H&E
Breast_H1_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has NDUFA11 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
NDUFA11	GOBP_Atp_Metabolic_Process	Human	Bladder	rep_4	3.6e-11
NDUFA11	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Human	Bladder	rep_4	7.2e-24
NDUFA11	GOBP_Cellular_Respiration	Human	Bladder	rep_4	2.0e-15
NDUFA11	GOBP_Electron_Transport_Chain	Human	Bladder	rep_4	1.0e-20
NDUFA11	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Bladder	rep_4	1.5e-12
NDUFA11	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Bladder	rep_4	3.4e-12
NDUFA11	GOBP_Mitochondrial_Electron_Transport_Nadh_To_Ubiquinone	Human	Bladder	rep_4	2.0e-11
NDUFA11	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Bladder	rep_4	1.8e-09
NDUFA11	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Bladder	rep_4	1.1e-14
NDUFA11	GOBP_Oxidative_Phosphorylation	Human	Bladder	rep_4	4.6e-17
NDUFA11	GOBP_Respiratory_Electron_Transport_Chain	Human	Bladder	rep_4	4.7e-21
NDUFA11	GOBP_Atp_Metabolic_Process	Human	Intestine	A3	7.9e-14
NDUFA11	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Human	Intestine	A3	2.3e-18
NDUFA11	GOBP_Cellular_Respiration	Human	Intestine	A3	6.2e-15
NDUFA11	GOBP_Electron_Transport_Chain	Human	Intestine	A3	1.4e-19
NDUFA11	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Intestine	A3	2.5e-12
NDUFA11	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Intestine	A3	4.3e-14
NDUFA11	GOBP_Mitochondrial_Electron_Transport_Nadh_To_Ubiquinone	Human	Intestine	A3	5.9e-12
NDUFA11	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Intestine	A3	1.5e-07
NDUFA11	GOBP_Mitochondrion_Organization	Human	Intestine	A3	2.3e-19
NDUFA11	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Intestine	A3	3.9e-07
NDUFA11	GOBP_Oxidative_Phosphorylation	Human	Intestine	A3	1.2e-13
NDUFA11	GOBP_Respiratory_Electron_Transport_Chain	Human	Intestine	A3	7.5e-17
NDUFA11	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Pancreas	PDAC-B-st1	9.9e-05
NDUFA11	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Pancreas	PDAC-B-st1	4.6e-05
NDUFA11	GOBP_Atp_Metabolic_Process	Human	Uterus	rep_26	3.2e-08
NDUFA11	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Human	Uterus	rep_26	2.1e-08
NDUFA11	GOBP_Cellular_Respiration	Human	Uterus	rep_26	3.7e-07
NDUFA11	GOBP_Electron_Transport_Chain	Human	Uterus	rep_26	1.9e-08
NDUFA11	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Uterus	rep_26	7.2e-06
NDUFA11	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Uterus	rep_26	1.8e-06
NDUFA11	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Uterus	rep_26	2.3e-06
NDUFA11	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Human	Uterus	rep_26	9.9e-07
NDUFA11	GOBP_Oxidative_Phosphorylation	Human	Uterus	rep_26	2.6e-09
NDUFA11	GOBP_Respiratory_Electron_Transport_Chain	Human	Uterus	rep_26	2.1e-08
NDUFA11	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Human	Breast	rep_5	3.1e-04
NDUFA11	GOBP_Electron_Transport_Chain	Human	Breast	rep_5	6.2e-04
NDUFA11	GOBP_Mitochondrial_Electron_Transport_Nadh_To_Ubiquinone	Human	Breast	rep_5	2.9e-07
NDUFA11	GOBP_Oxidative_Phosphorylation	Human	Breast	rep_5	1.1e-04
NDUFA11	GOBP_Respiratory_Electron_Transport_Chain	Human	Breast	rep_5	3.1e-04
NDUFA11	GOBP_Atp_Metabolic_Process	Human	Breast	rep_6	1.3e-06
NDUFA11	GOBP_Cellular_Respiration	Human	Breast	rep_6	2.2e-06
NDUFA11	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Breast	rep_6	5.2e-08
NDUFA11	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Breast	rep_6	7.1e-09
NDUFA11	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Human	Breast	rep_6	3.3e-04
NDUFA11	GOBP_Mitochondrion_Organization	Human	Breast	rep_6	2.0e-05

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NDUFA11 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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NDUFA11 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for NDUFA11 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for NDUFA11

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
NDUFA11	Q86Y39	DB00157	NADH	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	SmallMoleculeDrug	approved\|nutraceutical

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Related Diseases for NDUFA11

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
NDUFA11	C1838979	MITOCHONDRIAL COMPLEX I DEFICIENCY	3	GENOMICS_ENGLAND;ORPHANET
NDUFA11	C0751651	Mitochondrial Diseases	1	GENOMICS_ENGLAND