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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: AFMID (spascer ID:125061)

Gene summary for AFMID

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

AFMID

Gene ID

125061

Gene namearylformamidase
SynonymsFKF|KF|KFA
Cytomap17q25.3
Type of geneprotein-coding
Descriptionkynurenine formamidaseKFaseN-formylkynurenine formamidaseprobable arylformamidase
Modification date20220513
UniProtAcc

Q63HM1


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
AFMID

GO:0005737

cytoplasm

21873635

Component
AFMID

GO:0016787

hydrolase activity

21873635

Function
AFMID

GO:0019441

tryptophan catabolic process to kynurenine

21873635

Process

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Spatial pattern events for AFMID

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
AFMIDHumanBrainrep_9 335586951.01e-14
AFMIDHumanBrainrep_10 335586954.76e-09
AFMIDHumanBrainrep_11 335586952.49e-10
AFMIDHumanBrainrep_12 335586953.33e-07
AFMIDHumanIntestinerep_colon4 344172251.14e-15
AFMIDHumanLiverrep_liver1 344172251.08e-15
AFMIDHumanLiverrep_liver2 344172251.78e-13
AFMIDHumanLiverrep_liver3 344172254.34e-07
AFMIDHumanUterusrep_3 348579545.81e-15
AFMIDHumanHeartw6_s4 318350372.24e-04

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_9_H&E
boxplot

boxplot
Brain_rep_10_H&E
boxplot

boxplot
Brain_rep_11_H&E
boxplot

boxplot
Brain_rep_12_H&E
boxplot

boxplot
Intestine_rep_colon4_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Liver_rep_liver3_H&E
boxplot

boxplot
Uterus_rep_3_H&E
boxplot

boxplot


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Spatial pattern pathway has AFMID envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
AFMIDGOBP_Nucleoside_Phosphate_Biosynthetic_ProcessHumanBladderrep_4 1.4e-09
AFMIDGOBP_Organophosphate_Biosynthetic_ProcessHumanBladderrep_4 3.2e-09
AFMIDGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessHumanIntestineA3 9.9e-10
AFMIDGOBP_Nucleoside_Phosphate_Biosynthetic_ProcessHumanIntestineA3 1.6e-10
AFMIDGOBP_Organic_Cyclic_Compound_Catabolic_ProcessHumanIntestineA3 5.9e-24
AFMIDGOBP_Organonitrogen_Compound_Catabolic_ProcessHumanIntestineA3 4.5e-13
AFMIDGOBP_Organophosphate_Biosynthetic_ProcessHumanIntestineA3 2.2e-07
AFMIDGOBP_Organophosphate_Metabolic_ProcessHumanIntestineA3 4.4e-13
AFMIDGOBP_Alpha_Amino_Acid_Metabolic_ProcessHumanIntestineA8 7.0e-13
AFMIDGOBP_Amine_Catabolic_ProcessHumanIntestineA8 3.4e-19
AFMIDGOBP_Amine_Metabolic_ProcessHumanIntestineA8 7.2e-16
AFMIDGOBP_Aromatic_Amino_Acid_Family_Catabolic_ProcessHumanIntestineA8 3.7e-11
AFMIDGOBP_Aromatic_Amino_Acid_Family_Metabolic_ProcessHumanIntestineA8 6.9e-12
AFMIDGOBP_Benzene_Containing_Compound_Metabolic_ProcessHumanIntestineA8 6.1e-26
AFMIDGOBP_Cellular_Amino_Acid_Catabolic_ProcessHumanIntestineA8 2.5e-14
AFMIDGOBP_Cellular_Amino_Acid_Metabolic_ProcessHumanIntestineA8 5.3e-13
AFMIDGOBP_Cellular_Ketone_Metabolic_ProcessHumanIntestineA8 1.2e-11
AFMIDGOBP_De_Novo_Nad_Biosynthetic_ProcessHumanIntestineA8 3.3e-15
AFMIDGOBP_Indolalkylamine_Metabolic_ProcessHumanIntestineA8 6.4e-26
AFMIDGOBP_Indole_Containing_Compound_Metabolic_ProcessHumanIntestineA8 7.6e-27
AFMIDGOBP_Organic_Acid_Catabolic_ProcessHumanIntestineA8 1.6e-12
AFMIDGOBP_Organic_Acid_Metabolic_ProcessHumanIntestineA8 2.5e-18
AFMIDGOBP_Pyridine_Containing_Compound_Biosynthetic_ProcessHumanIntestineA8 8.0e-18
AFMIDGOBP_Pyridine_Containing_Compound_Metabolic_ProcessHumanIntestineA8 7.1e-14
AFMIDGOBP_Small_Molecule_Catabolic_ProcessHumanIntestineA8 2.2e-13
AFMIDGOBP_Small_Molecule_Metabolic_ProcessHumanIntestineA8 2.1e-15
AFMIDGOBP_Tryptophan_Catabolic_ProcessHumanIntestineA8 8.9e-11
AFMIDGOBP_Cellular_Amino_Acid_Metabolic_ProcessHumanPancreasPDAC-A-st2 9.6e-05
AFMIDGOBP_De_Novo_Nad_Biosynthetic_ProcessHumanPancreasPDAC-A-st2 3.9e-05
AFMIDGOBP_Indolalkylamine_Metabolic_ProcessHumanPancreasPDAC-A-st2 1.0e-08
AFMIDGOBP_Alpha_Amino_Acid_Catabolic_ProcessHumanUterusrep_25 1.2e-11
AFMIDGOBP_Amine_Catabolic_ProcessHumanUterusrep_25 1.9e-13
AFMIDGOBP_Aromatic_Amino_Acid_Family_Catabolic_ProcessHumanUterusrep_25 1.6e-11
AFMIDGOBP_Aromatic_Amino_Acid_Family_Metabolic_ProcessHumanUterusrep_25 1.1e-07
AFMIDGOBP_Benzene_Containing_Compound_Metabolic_ProcessHumanUterusrep_25 1.2e-08
AFMIDGOBP_De_Novo_Nad_Biosynthetic_ProcessHumanUterusrep_25 4.7e-07
AFMIDGOBP_Indolalkylamine_Metabolic_ProcessHumanUterusrep_25 7.6e-06
AFMIDGOBP_Indole_Containing_Compound_Metabolic_ProcessHumanUterusrep_25 5.6e-09
AFMIDGOBP_Kynurenine_Metabolic_ProcessHumanUterusrep_25 1.3e-08
AFMIDGOBP_Pyridine_Containing_Compound_Biosynthetic_ProcessHumanUterusrep_25 3.3e-08
AFMIDGOBP_Pyridine_Containing_Compound_Metabolic_ProcessHumanUterusrep_25 1.9e-11
AFMIDGOBP_Tryptophan_Catabolic_ProcessHumanUterusrep_25 1.8e-09
AFMIDGOBP_Tryptophan_Catabolic_Process_To_KynurenineHumanUterusrep_25 6.3e-28
AFMIDGOBP_Alpha_Amino_Acid_Metabolic_ProcessHumanUterusrep_26 1.6e-06
AFMIDGOBP_Cellular_Amino_Acid_Catabolic_ProcessHumanUterusrep_26 3.2e-12
AFMIDGOBP_Cellular_Ketone_Metabolic_ProcessHumanUterusrep_26 3.2e-13
AFMIDGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessHumanUterusrep_26 2.4e-06
AFMIDGOBP_Nucleoside_Phosphate_Biosynthetic_ProcessHumanUterusrep_26 3.4e-15
AFMIDGOBP_Organic_Acid_Catabolic_ProcessHumanUterusrep_26 6.9e-09
AFMIDGOBP_Organic_Acid_Metabolic_ProcessHumanUterusrep_26 4.9e-06
AFMIDGOBP_Organic_Cyclic_Compound_Catabolic_ProcessHumanUterusrep_26 2.6e-06
AFMIDGOBP_Organonitrogen_Compound_Catabolic_ProcessHumanUterusrep_26 1.0e-08
AFMIDGOBP_Organophosphate_Biosynthetic_ProcessHumanUterusrep_26 8.0e-07
AFMIDGOBP_Small_Molecule_Catabolic_ProcessHumanUterusrep_26 9.1e-13
AFMIDGOBP_Amine_Catabolic_ProcessHumanBreastrep_1 3.8e-15
AFMIDGOBP_Amine_Metabolic_ProcessHumanBreastrep_1 4.2e-96
AFMIDGOBP_Aromatic_Amino_Acid_Family_Catabolic_ProcessHumanBreastrep_1 4.5e-36
AFMIDGOBP_Benzene_Containing_Compound_Metabolic_ProcessHumanBreastrep_1 1.5e-21
AFMIDGOBP_Cellular_Ketone_Metabolic_ProcessHumanBreastrep_1 6.1e-19
AFMIDGOBP_Indolalkylamine_Metabolic_ProcessHumanBreastrep_1 1.2e-06
AFMIDGOBP_Indole_Containing_Compound_Metabolic_ProcessHumanBreastrep_1 3.8e-65
AFMIDGOBP_Kynurenine_Metabolic_ProcessHumanBreastrep_1 6.1e-04
AFMIDGOBP_Organophosphate_Biosynthetic_ProcessHumanBreastrep_1 1.4e-07
AFMIDGOBP_Pyridine_Containing_Compound_Biosynthetic_ProcessHumanBreastrep_1 1.6e-38
AFMIDGOBP_Pyridine_Containing_Compound_Metabolic_ProcessHumanBreastrep_1 1.3e-34
AFMIDGOBP_Tryptophan_Catabolic_ProcessHumanBreastrep_1 5.6e-28
AFMIDGOBP_Tryptophan_Catabolic_Process_To_KynurenineHumanBreastrep_1 4.6e-05
AFMIDGOBP_De_Novo_Nad_Biosynthetic_ProcessHumanBreastrep_5 1.6e-14
AFMIDGOBP_Alpha_Amino_Acid_Catabolic_ProcessHumanBreastrep_6 2.6e-05
AFMIDGOBP_Alpha_Amino_Acid_Metabolic_ProcessHumanBreastrep_6 1.7e-08
AFMIDGOBP_Aromatic_Amino_Acid_Family_Metabolic_ProcessHumanBreastrep_6 4.0e-10
AFMIDGOBP_Cellular_Amino_Acid_Catabolic_ProcessHumanBreastrep_6 1.6e-05
AFMIDGOBP_Cellular_Amino_Acid_Metabolic_ProcessHumanBreastrep_6 1.0e-10
AFMIDGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessHumanBreastrep_6 1.7e-10
AFMIDGOBP_Nucleoside_Phosphate_Biosynthetic_ProcessHumanBreastrep_6 6.2e-07
AFMIDGOBP_Organic_Acid_Catabolic_ProcessHumanBreastrep_6 1.5e-11
AFMIDGOBP_Organic_Acid_Metabolic_ProcessHumanBreastrep_6 6.7e-05
AFMIDGOBP_Organic_Cyclic_Compound_Catabolic_ProcessHumanBreastrep_6 7.7e-08
AFMIDGOBP_Organonitrogen_Compound_Biosynthetic_ProcessHumanBreastrep_6 1.2e-09
AFMIDGOBP_Organonitrogen_Compound_Catabolic_ProcessHumanBreastrep_6 9.5e-06
AFMIDGOBP_Organophosphate_Metabolic_ProcessHumanBreastrep_6 1.0e-12
AFMIDGOBP_Small_Molecule_Catabolic_ProcessHumanBreastrep_6 4.7e-07
AFMIDGOBP_Small_Molecule_Metabolic_ProcessHumanBreastrep_6 5.5e-09
AFMIDGOBP_Amine_Catabolic_ProcessHumanSkinP10_rep1 1.5e-15
AFMIDGOBP_Indolalkylamine_Metabolic_ProcessHumanSkinP10_rep2 1.1e-10
AFMIDGOBP_Indole_Containing_Compound_Metabolic_ProcessHumanSkinP10_rep2 6.3e-08
AFMIDGOBP_Pyridine_Containing_Compound_Biosynthetic_ProcessHumanLungrep_1 3.2e-07
AFMIDGOBP_Pyridine_Containing_Compound_Metabolic_ProcessHumanLungrep_1 4.3e-07
AFMIDGOBP_Cellular_Ketone_Metabolic_ProcessHumanLungrep_2 2.1e-09

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AFMID function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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AFMID function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for AFMID envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for AFMID

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AFMID

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource