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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ACAP3 (spascer ID:116983)

Gene summary for ACAP3

Gene summary

Gene information
	Species	Human
	Gene symbol	ACAP3
	Gene ID	116983
	Gene name	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
	Synonyms	CENTB5
	Cytomap	1p36.33
	Type of gene	protein-coding
	Description	arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3centaurin-beta-5cnt-b5
	Modification date	20220513
	UniProtAcc	Q96P50

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for ACAP3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ACAP3	Human	Bladder	rep_3	34385456	2.72e-14
ACAP3	Human	Intestine	rep_colon1	34417225	3.42e-15
ACAP3	Human	Intestine	rep_colon2	34417225	6.37e-11
ACAP3	Human	Intestine	rep_colon4	34417225	1.37e-14
ACAP3	Human	Liver	rep_liver2	34417225	6.98e-16
ACAP3	Human	Intestine	A1	33406409	8.09e-06
ACAP3	Human	Intestine	A2	33406409	3.37e-10
ACAP3	Human	Intestine	A4	33406409	9.63e-15
ACAP3	Human	Uterus	rep_2	34857954	2.55e-15
ACAP3	Human	Uterus	rep_3	34857954	1.66e-15
ACAP3	Human	Breast	1160920F	34493872	1.48e-15
ACAP3	Human	Breast	CID4465	34493872	2.41e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_3_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver2_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A4_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E

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Spatial pattern pathway has ACAP3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ACAP3	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
ACAP3	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
ACAP3	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
ACAP3	GOBP_Neuron_Development	Human	Brain	rep_1	7.4e-34
ACAP3	GOBP_Neuron_Differentiation	Human	Brain	rep_1	7.4e-34
ACAP3	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
ACAP3	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_1	8.7e-71
ACAP3	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
ACAP3	GOBP_Regulation_Of_Hydrolase_Activity	Human	Brain	rep_2	2.1e-15
ACAP3	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
ACAP3	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
ACAP3	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
ACAP3	GOBP_Neuron_Development	Human	Liver	rep_1	1.5e-73
ACAP3	GOBP_Neuron_Differentiation	Human	Liver	rep_1	1.5e-73
ACAP3	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
ACAP3	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	4.9e-46
ACAP3	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
ACAP3	GOBP_Regulation_Of_Hydrolase_Activity	Human	Liver	rep_1	6.0e-76
ACAP3	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
ACAP3	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon2	4.1e-22
ACAP3	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
ACAP3	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	rep_colon4	3.7e-11
ACAP3	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
ACAP3	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
ACAP3	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
ACAP3	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
ACAP3	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
ACAP3	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
ACAP3	GOBP_Neuron_Development	Human	Intestine	A3	1.3e-12
ACAP3	GOBP_Neuron_Differentiation	Human	Intestine	A3	1.4e-11
ACAP3	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
ACAP3	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.8e-12
ACAP3	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	2.8e-16
ACAP3	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
ACAP3	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
ACAP3	GOBP_Regulation_Of_Gtpase_Activity	Human	Intestine	A3	1.0e-12
ACAP3	GOBP_Regulation_Of_Hydrolase_Activity	Human	Intestine	A3	7.3e-16
ACAP3	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Intestine	A3	2.0e-09
ACAP3	GOBP_Regulation_Of_Gtpase_Activity	Human	Pancreas	PDAC-B-st1	9.7e-05
ACAP3	GOBP_Regulation_Of_Hydrolase_Activity	Human	Uterus	rep_29	6.6e-10
ACAP3	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
ACAP3	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
ACAP3	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
ACAP3	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
ACAP3	GOBP_Neuron_Development	Human	Breast	rep_1	2.5e-26
ACAP3	GOBP_Neuron_Differentiation	Human	Breast	rep_1	1.1e-16
ACAP3	GOBP_Positive_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	1.4e-13
ACAP3	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_1	7.8e-04
ACAP3	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
ACAP3	GOBP_Regulation_Of_Gtpase_Activity	Human	Breast	rep_1	9.6e-08
ACAP3	GOBP_Regulation_Of_Neuron_Projection_Development	Human	Breast	rep_1	7.3e-24
ACAP3	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
ACAP3	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
ACAP3	GOBP_Regulation_Of_Hydrolase_Activity	Human	Breast	rep_5	3.2e-13
ACAP3	GOBP_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_1	4.1e-07
ACAP3	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Human	Lung	rep_2	7.9e-07

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ACAP3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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ACAP3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for ACAP3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for ACAP3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ACAP3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source