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Spatial pattern gene: TRMT61A (spascer ID:115708) |
Gene summary for TRMT61A |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | TRMT61A | Gene ID | 115708 |
| Gene name | tRNA methyltransferase 61A |
| Synonyms | C14orf172|GCD14|Gcd14p|TRM61|hTRM61 |
| Cytomap | 14q32.33 |
| Type of gene | protein-coding |
| Description | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61AmRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61AtRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61tRNA (adenine-N(1)-)-methyltransferase catalytic subun |
| Modification date | 20220513 |
| UniProtAcc | Q96FX7 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| TRMT61A | GO:0005634 | nucleus | 21873635 | Component |
| TRMT61A | GO:0030488 | tRNA methylation | 21873635 | Process |
| TRMT61A | GO:0031515 | tRNA (m1A) methyltransferase complex | 21873635 | Component |
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Spatial pattern events for TRMT61A |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| TRMT61A | Human | Intestine | rep_colon1 | 34417225 | 6.62e-07 |
| TRMT61A | Human | Intestine | rep_colon2 | 34417225 | 1.02e-06 |
| TRMT61A | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| TRMT61A | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| TRMT61A | Human | Uterus | rep_2 | 34857954 | 2.55e-15 |
| TRMT61A | Human | Uterus | rep_3 | 34857954 | 1.66e-15 |
| TRMT61A | Human | Breast | 1160920F | 34493872 | 2.68e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_2_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_1160920F_H&E  |  |
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Spatial pattern pathway has TRMT61A envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| TRMT61A | GOBP_Methylation | Human | Intestine | A3 | 5.9e-09 |
| TRMT61A | GOBP_Mrna_Metabolic_Process | Human | Intestine | A3 | 7.7e-20 |
| TRMT61A | GOBP_Ncrna_Metabolic_Process | Human | Intestine | A3 | 8.6e-07 |
| TRMT61A | GOBP_Rna_Methylation | Human | Intestine | A3 | 2.7e-07 |
| TRMT61A | GOBP_Rna_Modification | Human | Intestine | A3 | 4.5e-10 |
| TRMT61A | GOBP_Rna_Processing | Human | Intestine | A3 | 3.9e-09 |
| TRMT61A | GOBP_Trna_Metabolic_Process | Human | Intestine | A3 | 2.5e-12 |
| TRMT61A | GOBP_Trna_Methylation | Human | Intestine | A3 | 1.7e-07 |
| TRMT61A | GOBP_Trna_Processing | Human | Intestine | A3 | 1.6e-08 |
| TRMT61A | GOBP_Mrna_Methylation | Human | Intestine | A8 | 4.4e-24 |
| TRMT61A | GOBP_Mrna_Metabolic_Process | Human | Pancreas | PDAC-B-st1 | 2.6e-05 |
| TRMT61A | GOBP_Ncrna_Processing | Human | Uterus | rep_1 | 4.5e-06 |
| TRMT61A | GOBP_Mrna_Methylation | Human | Uterus | rep_25 | 9.7e-06 |
| TRMT61A | GOBP_Mrna_Modification | Human | Uterus | rep_25 | 2.3e-07 |
| TRMT61A | GOBP_Methylation | Human | Uterus | rep_26 | 1.9e-06 |
| TRMT61A | GOBP_Rna_Methylation | Human | Uterus | rep_26 | 6.8e-13 |
| TRMT61A | GOBP_Trna_Metabolic_Process | Human | Uterus | rep_26 | 9.4e-08 |
| TRMT61A | GOBP_Trna_Methylation | Human | Uterus | rep_26 | 3.1e-10 |
| TRMT61A | GOBP_Methylation | Human | Breast | rep_6 | 1.7e-06 |
| TRMT61A | GOBP_Mrna_Metabolic_Process | Human | Breast | rep_6 | 3.0e-08 |
| TRMT61A | GOBP_Mrna_Modification | Human | Breast | rep_6 | 2.1e-06 |
| TRMT61A | GOBP_Ncrna_Metabolic_Process | Human | Breast | rep_6 | 1.9e-04 |
| TRMT61A | GOBP_Ncrna_Processing | Human | Breast | rep_6 | 1.3e-05 |
| TRMT61A | GOBP_Rna_Methylation | Human | Breast | rep_6 | 3.8e-05 |
| TRMT61A | GOBP_Rna_Modification | Human | Breast | rep_6 | 1.0e-04 |
| TRMT61A | GOBP_Rna_Processing | Human | Breast | rep_6 | 3.5e-06 |
| TRMT61A | GOBP_Trna_Metabolic_Process | Human | Breast | rep_6 | 3.9e-05 |
| TRMT61A | GOBP_Trna_Processing | Human | Breast | rep_6 | 3.5e-08 |
| TRMT61A | GOBP_Mrna_Methylation | Human | Skin | P5_rep1 | 6.2e-13 |
| TRMT61A | GOBP_Trna_Methylation | Human | Skin | P5_rep1 | 8.2e-13 |
| TRMT61A | GOBP_Trna_Modification | Human | Skin | P5_rep1 | 4.1e-14 |
| TRMT61A | GOBP_Mrna_Metabolic_Process | Human | Skin | P5_rep3 | 1.8e-08 |
| TRMT61A | GOBP_Mrna_Modification | Human | Skin | P10_rep2 | 2.1e-11 |
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TRMT61A function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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TRMT61A function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for TRMT61A envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for TRMT61A |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for TRMT61A |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
