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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CDCA5 (spascer ID:113130)

Gene summary for CDCA5

Gene summary

Gene information
	Species	Human
	Gene symbol	CDCA5
	Gene ID	113130
	Gene name	cell division cycle associated 5
	Synonyms	SORORIN
	Cytomap	11q13.1
	Type of gene	protein-coding
	Description	sororincell division cycle-associated protein 5p35
	Modification date	20220515
	UniProtAcc	Q96FF9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CDCA5	GO:0005634	nucleus	21873635	Component
CDCA5	GO:0006302	double-strand break repair	21873635	Process
CDCA5	GO:0007064	mitotic sister chromatid cohesion	21873635	Process
CDCA5	GO:0007080	mitotic metaphase plate congression	21873635	Process
CDCA5	GO:0031536	positive regulation of exit from mitosis	21873635	Process
CDCA5	GO:0071922	regulation of cohesin loading	21873635	Process

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Spatial pattern events for CDCA5

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CDCA5	Human	Bladder	rep_1	34385456	2.80e-14
CDCA5	Human	Intestine	rep_colon1	34417225	2.64e-13
CDCA5	Human	Liver	rep_liver1	34417225	1.08e-15
CDCA5	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Bladder_rep_1_H&E
Intestine_rep_colon1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has CDCA5 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CDCA5	GOBP_Regulation_Of_Protein_Localization	Human	Brain	rep_4	1.0e-14
CDCA5	GOBP_Regulation_Of_Protein_Localization	Human	Liver	rep_1	2.1e-52
CDCA5	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	rep_colon2	1.5e-57
CDCA5	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
CDCA5	GOBP_Cell_Cycle_Phase_Transition	Human	Intestine	A3	3.5e-07
CDCA5	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
CDCA5	GOBP_Cell_Division	Human	Intestine	A3	2.7e-10
CDCA5	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
CDCA5	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Intestine	A3	6.6e-16
CDCA5	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
CDCA5	GOBP_Chromosome_Segregation	Human	Intestine	A3	4.7e-12
CDCA5	GOBP_Dna_Conformation_Change	Human	Intestine	A3	9.8e-12
CDCA5	GOBP_Dna_Metabolic_Process	Human	Intestine	A3	1.2e-09
CDCA5	GOBP_Dna_Packaging	Human	Intestine	A3	6.2e-08
CDCA5	GOBP_Dna_Repair	Human	Intestine	A3	4.4e-09
CDCA5	GOBP_Double_Strand_Break_Repair	Human	Intestine	A3	3.1e-09
CDCA5	GOBP_Establishment_Of_Organelle_Localization	Human	Intestine	A3	9.7e-13
CDCA5	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
CDCA5	GOBP_Mitotic_Chromosome_Condensation	Human	Intestine	A3	2.2e-08
CDCA5	GOBP_Mitotic_Nuclear_Division	Human	Intestine	A3	5.1e-12
CDCA5	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Intestine	A3	6.7e-13
CDCA5	GOBP_Nuclear_Chromosome_Segregation	Human	Intestine	A3	4.3e-09
CDCA5	GOBP_Organelle_Fission	Human	Intestine	A3	3.4e-16
CDCA5	GOBP_Organelle_Localization	Human	Intestine	A3	5.1e-12
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Intestine	A3	3.2e-16
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	1.3e-18
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	2.3e-19
CDCA5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	2.6e-15
CDCA5	GOBP_Protein_Localization_To_Chromatin	Human	Intestine	A3	5.2e-13
CDCA5	GOBP_Protein_Localization_To_Chromosome	Human	Intestine	A3	6.2e-07
CDCA5	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
CDCA5	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
CDCA5	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	2.6e-08
CDCA5	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
CDCA5	GOBP_Regulation_Of_Cellular_Localization	Human	Intestine	A3	4.5e-11
CDCA5	GOBP_Regulation_Of_Chromosome_Organization	Human	Intestine	A3	3.2e-08
CDCA5	GOBP_Regulation_Of_Exit_From_Mitosis	Human	Intestine	A3	4.7e-12
CDCA5	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
CDCA5	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
CDCA5	GOBP_Regulation_Of_Protein_Localization	Human	Intestine	A3	7.5e-08
CDCA5	GOBP_Sister_Chromatid_Segregation	Human	Intestine	A3	1.0e-11
CDCA5	GOBP_Establishment_Of_Sister_Chromatid_Cohesion	Human	Intestine	A8	1.0e-29
CDCA5	GOBP_Metaphase_Plate_Congression	Human	Intestine	A8	4.8e-08
CDCA5	GOBP_Mitotic_Metaphase_Plate_Congression	Human	Intestine	A8	6.0e-09
CDCA5	GOBP_Mitotic_Sister_Chromatid_Cohesion	Human	Intestine	A8	1.6e-22
CDCA5	GOBP_Regulation_Of_Protein_Localization_To_Chromatin	Human	Intestine	A8	5.6e-13
CDCA5	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Intestine	A8	4.4e-08
CDCA5	GOBP_Sister_Chromatid_Cohesion	Human	Intestine	A8	5.4e-21
CDCA5	GOBP_Cell_Division	Human	Pancreas	PDAC-B-st1	5.8e-05
CDCA5	GOBP_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
CDCA5	GOBP_Nuclear_Chromosome_Segregation	Human	Pancreas	PDAC-B-st1	3.3e-05
CDCA5	GOBP_Organelle_Fission	Human	Pancreas	PDAC-B-st1	3.9e-05
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Pancreas	PDAC-B-st1	4.0e-05
CDCA5	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Pancreas	PDAC-B-st1	7.2e-05
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_1	6.5e-06
CDCA5	GOBP_Dna_Packaging	Human	Uterus	rep_25	9.6e-06
CDCA5	GOBP_Mitotic_Metaphase_Plate_Congression	Human	Uterus	rep_25	5.1e-07
CDCA5	GOBP_Mitotic_Sister_Chromatid_Cohesion	Human	Uterus	rep_25	4.6e-09
CDCA5	GOBP_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	1.9e-06
CDCA5	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Uterus	rep_26	2.4e-07
CDCA5	GOBP_Chromosome_Condensation	Human	Uterus	rep_26	7.7e-16
CDCA5	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
CDCA5	GOBP_Chromosome_Segregation	Human	Uterus	rep_26	5.6e-19
CDCA5	GOBP_Cohesin_Loading	Human	Uterus	rep_26	1.1e-07
CDCA5	GOBP_Dna_Conformation_Change	Human	Uterus	rep_26	1.2e-14
CDCA5	GOBP_Exit_From_Mitosis	Human	Uterus	rep_26	4.7e-10
CDCA5	GOBP_Metaphase_Plate_Congression	Human	Uterus	rep_26	3.1e-08
CDCA5	GOBP_Mitotic_Chromosome_Condensation	Human	Uterus	rep_26	1.2e-08
CDCA5	GOBP_Mitotic_Nuclear_Division	Human	Uterus	rep_26	2.4e-07
CDCA5	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Uterus	rep_26	4.0e-12
CDCA5	GOBP_Nuclear_Chromosome_Segregation	Human	Uterus	rep_26	1.5e-12
CDCA5	GOBP_Organelle_Fission	Human	Uterus	rep_26	6.0e-11
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Uterus	rep_26	2.1e-09
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Uterus	rep_26	1.2e-15
CDCA5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.1e-08
CDCA5	GOBP_Protein_Localization_To_Chromatin	Human	Uterus	rep_26	5.2e-11
CDCA5	GOBP_Protein_Localization_To_Chromosome	Human	Uterus	rep_26	3.4e-10
CDCA5	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	9.3e-07
CDCA5	GOBP_Regulation_Of_Chromosome_Organization	Human	Uterus	rep_26	3.5e-08
CDCA5	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
CDCA5	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Uterus	rep_26	1.2e-08
CDCA5	GOBP_Sister_Chromatid_Cohesion	Human	Uterus	rep_26	3.1e-15
CDCA5	GOBP_Sister_Chromatid_Segregation	Human	Uterus	rep_26	3.3e-13
CDCA5	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
CDCA5	GOBP_Establishment_Of_Organelle_Localization	Human	Breast	rep_1	6.5e-08
CDCA5	GOBP_Organelle_Localization	Human	Breast	rep_1	1.8e-08
CDCA5	GOBP_Regulation_Of_Cellular_Localization	Human	Breast	rep_1	5.5e-07
CDCA5	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
CDCA5	GOBP_Regulation_Of_Protein_Localization	Human	Breast	rep_1	2.8e-21
CDCA5	GOBP_Establishment_Of_Sister_Chromatid_Cohesion	Human	Breast	rep_3	6.2e-06
CDCA5	GOBP_Cohesin_Loading	Human	Breast	rep_5	1.6e-04
CDCA5	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
CDCA5	GOBP_Regulation_Of_Protein_Localization_To_Chromatin	Human	Breast	rep_5	1.6e-05
CDCA5	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
CDCA5	GOBP_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	4.9e-09
CDCA5	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
CDCA5	GOBP_Cell_Division	Human	Breast	rep_6	8.2e-07
CDCA5	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Human	Breast	rep_6	6.0e-06
CDCA5	GOBP_Chromosome_Localization	Human	Breast	rep_6	1.4e-04
CDCA5	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
CDCA5	GOBP_Chromosome_Segregation	Human	Breast	rep_6	1.9e-05
CDCA5	GOBP_Dna_Conformation_Change	Human	Breast	rep_6	1.4e-05
CDCA5	GOBP_Dna_Metabolic_Process	Human	Breast	rep_6	1.4e-10
CDCA5	GOBP_Dna_Packaging	Human	Breast	rep_6	1.9e-04
CDCA5	GOBP_Dna_Repair	Human	Breast	rep_6	1.0e-09
CDCA5	GOBP_Double_Strand_Break_Repair	Human	Breast	rep_6	2.0e-09
CDCA5	GOBP_Exit_From_Mitosis	Human	Breast	rep_6	6.0e-10
CDCA5	GOBP_Metaphase_Plate_Congression	Human	Breast	rep_6	2.6e-06
CDCA5	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
CDCA5	GOBP_Mitotic_Metaphase_Plate_Congression	Human	Breast	rep_6	3.4e-08
CDCA5	GOBP_Mitotic_Nuclear_Division	Human	Breast	rep_6	2.5e-08
CDCA5	GOBP_Mitotic_Sister_Chromatid_Cohesion	Human	Breast	rep_6	9.0e-05
CDCA5	GOBP_Mitotic_Sister_Chromatid_Segregation	Human	Breast	rep_6	4.0e-04
CDCA5	GOBP_Nuclear_Chromosome_Segregation	Human	Breast	rep_6	4.6e-06
CDCA5	GOBP_Organelle_Fission	Human	Breast	rep_6	3.0e-05
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Breast	rep_6	7.0e-10
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	1.4e-09
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	7.5e-09
CDCA5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	2.5e-13
CDCA5	GOBP_Protein_Localization_To_Chromosome	Human	Breast	rep_6	2.2e-10
CDCA5	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
CDCA5	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	2.7e-07
CDCA5	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
CDCA5	GOBP_Regulation_Of_Chromosome_Organization	Human	Breast	rep_6	3.0e-04
CDCA5	GOBP_Regulation_Of_Exit_From_Mitosis	Human	Breast	rep_6	6.8e-09
CDCA5	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
CDCA5	GOBP_Sister_Chromatid_Cohesion	Human	Breast	rep_6	1.9e-04
CDCA5	GOBP_Sister_Chromatid_Segregation	Human	Breast	rep_6	5.3e-04
CDCA5	GOBP_Regulation_Of_Protein_Localization_To_Chromatin	Human	Skin	P2_rep2	2.0e-08
CDCA5	GOBP_Dna_Conformation_Change	Human	Skin	P5_rep1	1.8e-15
CDCA5	GOBP_Dna_Repair	Human	Skin	P5_rep1	1.7e-08
CDCA5	GOBP_Nuclear_Chromosome_Segregation	Human	Skin	P5_rep1	7.9e-09
CDCA5	GOBP_Organelle_Localization	Human	Skin	P5_rep1	2.1e-13
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle	Human	Skin	P5_rep1	7.8e-10
CDCA5	GOBP_Positive_Regulation_Of_Cell_Cycle_Process	Human	Skin	P5_rep1	4.9e-14
CDCA5	GOBP_Positive_Regulation_Of_Mitotic_Cell_Cycle	Human	Skin	P5_rep1	8.2e-10
CDCA5	GOBP_Mitotic_Sister_Chromatid_Cohesion	Human	Skin	P5_rep3	2.5e-08
CDCA5	GOBP_Organelle_Fission	Human	Skin	P5_rep3	1.0e-09
CDCA5	GOBP_Cohesin_Loading	Human	Skin	P10_rep1	2.7e-11
CDCA5	GOBP_Mitotic_Chromosome_Condensation	Human	Skin	P10_rep1	2.6e-25
CDCA5	GOBP_Establishment_Of_Sister_Chromatid_Cohesion	Human	Skin	P10_rep2	1.4e-14
CDCA5	GOBP_Protein_Localization_To_Chromatin	Human	Skin	P10_rep2	3.2e-18
CDCA5	GOBP_Regulation_Of_Sister_Chromatid_Cohesion	Human	Skin	P10_rep2	9.2e-18
CDCA5	GOBP_Regulation_Of_Exit_From_Mitosis	Human	Skin	P10_rep3	4.4e-12

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CDCA5 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CDCA5 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CDCA5 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CDCA5

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CDCA5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CDCA5	C2239176	Liver carcinoma	1	CTD_human