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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: PLCD3 (spascer ID:113026)

Gene summary for PLCD3

Gene summary

Gene information
	Species	Human
	Gene symbol	PLCD3
	Gene ID	113026
	Gene name	phospholipase C delta 3
	Synonyms	PLC-delta-3
	Cytomap	17q21.31
	Type of gene	protein-coding
	Description	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-31-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3PLC delta3phosphoinositide phospholipase C-delta-3
	Modification date	20220513
	UniProtAcc	Q8N3E9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
PLCD3	GO:0004435	phosphatidylinositol phospholipase C activity	21873635	Function
PLCD3	GO:0048015	phosphatidylinositol-mediated signaling	21873635	Process

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Spatial pattern events for PLCD3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
PLCD3	Human	Brain	rep_9	33558695	2.09e-07
PLCD3	Human	Intestine	rep_colon1	34417225	1.95e-15
PLCD3	Human	Intestine	rep_colon2	34417225	8.12e-16
PLCD3	Human	Intestine	rep_colon4	34417225	1.14e-15
PLCD3	Human	Liver	rep_liver1	34417225	1.08e-15
PLCD3	Human	Intestine	A1	33406409	2.09e-15
PLCD3	Human	Intestine	A2	33406409	2.47e-15
PLCD3	Human	Uterus	rep_1	34857954	5.15e-08
PLCD3	Human	Uterus	rep_2	34857954	2.02e-13
PLCD3	Human	Uterus	rep_3	34857954	1.00e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_9_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Uterus_rep_1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E

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Spatial pattern pathway has PLCD3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
PLCD3	GOBP_Lipid_Metabolic_Process	Human	Brain	rep_1	2.8e-23
PLCD3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Brain	rep_4	4.1e-17
PLCD3	GOBP_Blood_Vessel_Morphogenesis	Human	Brain	rep_4	4.1e-17
PLCD3	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
PLCD3	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
PLCD3	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
PLCD3	GOBP_Vasculature_Development	Human	Brain	rep_4	4.1e-17
PLCD3	GOBP_Blood_Vessel_Morphogenesis	Human	Bladder	rep_2	9.4e-07
PLCD3	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
PLCD3	GOBP_Vasculature_Development	Human	Bladder	rep_2	2.0e-14
PLCD3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Liver	rep_1	6.0e-76
PLCD3	GOBP_Blood_Vessel_Morphogenesis	Human	Liver	rep_1	6.0e-76
PLCD3	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
PLCD3	GOBP_Lipid_Metabolic_Process	Human	Liver	rep_1	1.0e-70
PLCD3	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
PLCD3	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
PLCD3	GOBP_Vasculature_Development	Human	Liver	rep_1	6.0e-76
PLCD3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
PLCD3	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
PLCD3	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
PLCD3	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
PLCD3	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
PLCD3	GOBP_Vasculature_Development	Human	Intestine	rep_colon4	1.9e-09
PLCD3	GOBP_Blood_Vessel_Morphogenesis	Human	Intestine	A3	4.7e-07
PLCD3	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
PLCD3	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Intestine	A3	2.7e-15
PLCD3	GOBP_Embryo_Development	Human	Intestine	A3	2.4e-07
PLCD3	GOBP_Embryonic_Organ_Development	Human	Intestine	A3	1.4e-10
PLCD3	GOBP_Embryonic_Placenta_Development	Human	Intestine	A3	6.1e-07
PLCD3	GOBP_Organophosphate_Metabolic_Process	Human	Intestine	A3	4.4e-13
PLCD3	GOBP_Placenta_Blood_Vessel_Development	Human	Intestine	A3	7.2e-07
PLCD3	GOBP_Placenta_Development	Human	Intestine	A3	2.1e-07
PLCD3	GOBP_Reproduction	Human	Intestine	A3	4.6e-19
PLCD3	GOBP_Reproductive_System_Development	Human	Intestine	A3	2.9e-14
PLCD3	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
PLCD3	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
PLCD3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	A8	3.3e-08
PLCD3	GOBP_Inositol_Lipid_Mediated_Signaling	Human	Intestine	A8	3.0e-18
PLCD3	GOBP_Inositol_Phosphate_Metabolic_Process	Human	Intestine	A8	3.1e-11
PLCD3	GOBP_Labyrinthine_Layer_Blood_Vessel_Development	Human	Intestine	A8	2.0e-20
PLCD3	GOBP_Labyrinthine_Layer_Development	Human	Intestine	A8	7.2e-23
PLCD3	GOBP_Lipid_Catabolic_Process	Human	Intestine	A8	3.2e-08
PLCD3	GOBP_Lipid_Metabolic_Process	Human	Intestine	A8	1.1e-11
PLCD3	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Intestine	A8	6.4e-10
PLCD3	GOBP_Polyol_Metabolic_Process	Human	Intestine	A8	6.2e-14
PLCD3	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
PLCD3	GOBP_Vasculature_Development	Human	Intestine	A8	9.3e-07
PLCD3	GOBP_Alcohol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
PLCD3	GOBP_Polyol_Metabolic_Process	Human	Pancreas	PDAC-B-st1	9.8e-06
PLCD3	GOBP_Labyrinthine_Layer_Blood_Vessel_Development	Human	Pancreas	PDAC-A-st2	2.1e-06
PLCD3	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Uterus	rep_1	1.6e-06
PLCD3	GOBP_Labyrinthine_Layer_Blood_Vessel_Development	Human	Uterus	rep_25	2.0e-07
PLCD3	GOBP_Alcohol_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
PLCD3	GOBP_Inositol_Phosphate_Metabolic_Process	Human	Uterus	rep_26	1.1e-15
PLCD3	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Uterus	rep_26	2.5e-08
PLCD3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Breast	rep_1	1.9e-98
PLCD3	GOBP_Blood_Vessel_Morphogenesis	Human	Breast	rep_1	1.5e-106
PLCD3	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
PLCD3	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Human	Breast	rep_1	7.7e-07
PLCD3	GOBP_In_Utero_Embryonic_Development	Human	Breast	rep_1	1.5e-18
PLCD3	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Human	Breast	rep_1	7.3e-16
PLCD3	GOBP_Placenta_Blood_Vessel_Development	Human	Breast	rep_1	6.1e-15
PLCD3	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
PLCD3	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
PLCD3	GOBP_Vasculature_Development	Human	Breast	rep_1	9.1e-95
PLCD3	GOBP_Developmental_Process_Involved_In_Reproduction	Human	Breast	rep_5	1.5e-12
PLCD3	GOBP_Embryo_Development	Human	Breast	rep_5	5.5e-08
PLCD3	GOBP_Embryonic_Organ_Development	Human	Breast	rep_5	3.3e-05
PLCD3	GOBP_Embryonic_Placenta_Development	Human	Breast	rep_5	8.0e-04
PLCD3	GOBP_Labyrinthine_Layer_Blood_Vessel_Development	Human	Breast	rep_5	1.5e-16
PLCD3	GOBP_Labyrinthine_Layer_Development	Human	Breast	rep_5	1.2e-10
PLCD3	GOBP_Lipid_Metabolic_Process	Human	Breast	rep_5	2.9e-06
PLCD3	GOBP_Placenta_Development	Human	Breast	rep_5	1.6e-05
PLCD3	GOBP_Reproduction	Human	Breast	rep_5	8.1e-06
PLCD3	GOBP_Reproductive_System_Development	Human	Breast	rep_5	3.6e-15
PLCD3	GOBP_Alcohol_Metabolic_Process	Human	Breast	rep_6	1.3e-04
PLCD3	GOBP_Inositol_Lipid_Mediated_Signaling	Human	Breast	rep_6	1.7e-11
PLCD3	GOBP_Lipid_Catabolic_Process	Human	Breast	rep_6	2.9e-05
PLCD3	GOBP_Organophosphate_Metabolic_Process	Human	Breast	rep_6	1.0e-12
PLCD3	GOBP_Polyol_Metabolic_Process	Human	Breast	rep_6	2.9e-05
PLCD3	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
PLCD3	GOBP_Labyrinthine_Layer_Blood_Vessel_Development	Human	Skin	P2_rep2	7.4e-08
PLCD3	GOBP_Placenta_Blood_Vessel_Development	Human	Skin	P5_rep1	6.8e-08
PLCD3	GOBP_Labyrinthine_Layer_Development	Human	Skin	P5_rep3	1.0e-09
PLCD3	GOBP_Lipid_Catabolic_Process	Human	Lung	rep_2	1.4e-09

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PLCD3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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PLCD3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for PLCD3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for PLCD3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for PLCD3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source