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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: MAN1A2 (spascer ID:10905)

Gene summary for MAN1A2

Gene summary

Gene information
	Species	Human
	Gene symbol	MAN1A2
	Gene ID	10905
	Gene name	mannosidase alpha class 1A member 2
	Synonyms	MAN1B
	Cytomap	1p12
	Type of gene	protein-coding
	Description	mannosyl-oligosaccharide 1,2-alpha-mannosidase IBalpha-1,2-mannosidase IBalpha1,2-mannosidaseprocessing alpha-1,2-mannosidase IB
	Modification date	20220513
	UniProtAcc	O60476

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
MAN1A2	GO:0000139	Golgi membrane	21873635	Component
MAN1A2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	21873635	Function
MAN1A2	GO:0005783	endoplasmic reticulum	21873635	Component
MAN1A2	GO:0006491	N-glycan processing	21873635	Process

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Spatial pattern events for MAN1A2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
MAN1A2	Human	Brain	rep_2	33558695	1.16e-13
MAN1A2	Human	Brain	rep_5	33558695	1.83e-14
MAN1A2	Human	Brain	rep_6	33558695	1.02e-06
MAN1A2	Human	Brain	rep_8	33558695	3.31e-14
MAN1A2	Human	Brain	rep_9	33558695	4.97e-09
MAN1A2	Human	Brain	rep_10	33558695	4.02e-07
MAN1A2	Human	Intestine	rep_colon2	34417225	8.12e-16
MAN1A2	Human	Intestine	rep_colon3	34417225	1.82e-15
MAN1A2	Human	Liver	rep_liver1	34417225	1.08e-15
MAN1A2	Human	Liver	rep_liver2	34417225	6.98e-16
MAN1A2	Human	Liver	rep_liver3	34417225	3.51e-15
MAN1A2	Human	Uterus	rep_2	34857954	2.55e-15
MAN1A2	Human	Breast	1142243F	34493872	2.30e-15
MAN1A2	Human	Breast	1160920F	34493872	1.40e-12
MAN1A2	Human	Breast	CID4465	34493872	3.45e-12
MAN1A2	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_2_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_8_H&E
Brain_rep_9_H&E
Brain_rep_10_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver3_H&E
Uterus_rep_2_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has MAN1A2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
MAN1A2	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
MAN1A2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Bladder	rep_4	3.0e-06
MAN1A2	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
MAN1A2	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
MAN1A2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Intestine	A3	1.8e-09
MAN1A2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
MAN1A2	GOBP_Carbohydrate_Metabolic_Process	Human	Intestine	A3	4.1e-08
MAN1A2	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
MAN1A2	GOBP_Glycoprotein_Biosynthetic_Process	Human	Intestine	A8	1.4e-09
MAN1A2	GOBP_Glycoprotein_Metabolic_Process	Human	Intestine	A8	5.3e-08
MAN1A2	GOBP_Glycosylation	Human	Intestine	A8	1.2e-17
MAN1A2	GOBP_Lung_Alveolus_Development	Human	Intestine	A8	1.0e-13
MAN1A2	GOBP_N_Glycan_Processing	Human	Intestine	A8	9.4e-10
MAN1A2	GOBP_Lung_Alveolus_Development	Human	Pancreas	PDAC-A-st2	1.5e-05
MAN1A2	GOBP_N_Glycan_Processing	Human	Uterus	rep_1	7.7e-07
MAN1A2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Uterus	rep_26	3.5e-11
MAN1A2	GOBP_Respiratory_System_Development	Human	Uterus	rep_26	1.3e-07
MAN1A2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Breast	rep_1	2.1e-06
MAN1A2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Human	Breast	rep_1	2.3e-22
MAN1A2	GOBP_Respiratory_System_Development	Human	Breast	rep_1	3.3e-47
MAN1A2	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
MAN1A2	GOBP_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	3.5e-10
MAN1A2	GOBP_Glycoprotein_Metabolic_Process	Human	Breast	rep_5	1.5e-14
MAN1A2	GOBP_Lung_Alveolus_Development	Human	Breast	rep_5	9.7e-05
MAN1A2	GOBP_Protein_Demannosylation	Human	Breast	rep_5	7.3e-15
MAN1A2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
MAN1A2	GOBP_Glycoprotein_Biosynthetic_Process	Human	Breast	rep_6	4.8e-07
MAN1A2	GOBP_Glycosylation	Human	Breast	rep_6	5.3e-04
MAN1A2	GOBP_N_Glycan_Processing	Human	Breast	rep_6	1.9e-09
MAN1A2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
MAN1A2	GOBP_Protein_Deglycosylation	Human	Breast	rep_6	6.2e-07
MAN1A2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Human	Skin	P5_rep1	1.9e-10
MAN1A2	GOBP_N_Glycan_Processing	Human	Skin	P10_rep2	1.1e-09

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MAN1A2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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MAN1A2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for MAN1A2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for MAN1A2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for MAN1A2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source