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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: BRD8 (spascer ID:10902)

Gene summary for BRD8

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

BRD8

Gene ID

10902

Gene namebromodomain containing 8
SynonymsSMAP|SMAP2|p120
Cytomap5q31.2
Type of geneprotein-coding
Descriptionbromodomain-containing protein 8skeletal muscle abundant protein 2thyroid hormone receptor coactivating protein of 120 kDatrCP120
Modification date20220513
UniProtAcc

Q9H0E9


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
BRD8

GO:0016573

histone acetylation

21873635

Process
BRD8

GO:0035267

NuA4 histone acetyltransferase complex

21873635

Component

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Spatial pattern events for BRD8

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
BRD8HumanBladderrep_2 343854569.38e-06
BRD8HumanIntestinerep_colon4 344172253.94e-15
BRD8HumanLiverrep_liver2 344172256.98e-16

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Bladder_rep_2_H&E
boxplot

boxplot
Intestine_rep_colon4_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot


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Spatial pattern pathway has BRD8 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
BRD8GOBP_GrowthHumanBrainrep_4 1.0e-14
BRD8GOBP_Response_To_Endogenous_StimulusHumanBrainrep_10 2.8e-23
BRD8GOBP_Response_To_HormoneHumanBrainrep_10 2.8e-23
BRD8GOBP_Response_To_Thyroid_HormoneHumanBrainrep_10 2.8e-23
BRD8GOBP_GrowthHumanLiverrep_1 2.1e-52
BRD8GOBP_Response_To_Endogenous_StimulusHumanLiverrep_1 3.0e-55
BRD8GOBP_Response_To_HormoneHumanLiverrep_1 3.0e-55
BRD8GOBP_Response_To_Thyroid_HormoneHumanLiverrep_1 3.0e-55
BRD8GOBP_GrowthHumanIntestinerep_colon2 1.5e-57
BRD8GOBP_Response_To_Endogenous_StimulusHumanIntestinerep_liver2 3.7e-39
BRD8GOBP_Response_To_HormoneHumanIntestinerep_liver2 3.7e-39
BRD8GOBP_Response_To_Thyroid_HormoneHumanIntestinerep_liver2 3.7e-39
BRD8GOBP_Cellular_Response_To_Hormone_StimulusHumanIntestineA3 8.7e-19
BRD8GOBP_Chromatin_OrganizationHumanIntestineA3 3.2e-11
BRD8GOBP_Chromosome_OrganizationHumanIntestineA3 2.5e-13
BRD8GOBP_GrowthHumanIntestineA3 3.3e-16
BRD8GOBP_Peptidyl_Amino_Acid_ModificationHumanIntestineA3 2.7e-09
BRD8GOBP_Peptidyl_Lysine_ModificationHumanIntestineA3 2.8e-09
BRD8GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanIntestineA3 5.1e-13
BRD8GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiHumanIntestineA3 9.4e-13
BRD8GOBP_Regulation_Of_GrowthHumanIntestineA3 3.6e-10
BRD8GOBP_Response_To_Endogenous_StimulusHumanIntestineA3 5.2e-09
BRD8GOBP_Cellular_Response_To_Thyroid_Hormone_StimulusHumanIntestineA8 3.4e-11
BRD8GOBP_Peptidyl_Lysine_AcetylationHumanIntestineA8 1.9e-08
BRD8GOBP_Protein_AcetylationHumanIntestineA8 6.7e-07
BRD8GOBP_Response_To_HormoneHumanIntestineA8 2.3e-13
BRD8GOBP_Response_To_Thyroid_HormoneHumanIntestineA8 4.9e-12
BRD8GOBP_Chromatin_OrganizationHumanUterusrep_1 1.9e-06
BRD8GOBP_Chromosome_OrganizationHumanUterusrep_26 1.2e-09
BRD8GOBP_Peptidyl_Lysine_ModificationHumanUterusrep_26 2.3e-09
BRD8GOBP_Response_To_Thyroid_HormoneHumanUterusrep_26 2.6e-12
BRD8GOBP_Histone_H4_AcetylationHumanUterusrep_29 7.2e-08
BRD8GOBP_Peptidyl_Lysine_AcetylationHumanUterusrep_29 6.7e-06
BRD8GOBP_Histone_H2a_AcetylationHumanBreastrep_11.9e-217
BRD8GOBP_Histone_H4_AcetylationHumanBreastrep_11.2e-121
BRD8GOBP_Peptidyl_Lysine_AcetylationHumanBreastrep_1 4.3e-46
BRD8GOBP_Protein_AcetylationHumanBreastrep_1 3.7e-29
BRD8GOBP_Protein_AcylationHumanBreastrep_1 1.9e-23
BRD8GOBP_Regulation_Of_GrowthHumanBreastrep_1 2.3e-04
BRD8GOBP_Response_To_Thyroid_HormoneHumanBreastrep_1 1.3e-27
BRD8GOBP_Cellular_Response_To_Hormone_StimulusHumanBreastrep_5 9.6e-12
BRD8GOBP_GrowthHumanBreastrep_5 5.4e-12
BRD8GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanBreastrep_5 8.0e-09
BRD8GOBP_Response_To_Endogenous_StimulusHumanBreastrep_5 3.6e-09
BRD8GOBP_Response_To_HormoneHumanBreastrep_5 2.9e-13
BRD8GOBP_Chromatin_OrganizationHumanBreastrep_6 4.3e-07
BRD8GOBP_Chromosome_OrganizationHumanBreastrep_6 1.1e-06
BRD8GOBP_Peptidyl_Amino_Acid_ModificationHumanBreastrep_6 3.8e-05
BRD8GOBP_Peptidyl_Lysine_ModificationHumanBreastrep_6 4.5e-08
BRD8GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiHumanBreastrep_6 4.2e-06
BRD8GOBP_Peptidyl_Lysine_AcetylationHumanSkinP5_rep1 1.5e-08
BRD8GOBP_Cellular_Response_To_Thyroid_Hormone_StimulusHumanSkinP10_rep1 1.8e-10
BRD8GOBP_Response_To_Thyroid_HormoneHumanSkinP10_rep1 1.6e-15

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BRD8 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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BRD8 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for BRD8 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for BRD8

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BRD8

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
BRD8C0014175Endometriosis1CTD_human
BRD8C0269102Endometrioma1CTD_human