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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: JTB (spascer ID:10899)

Gene summary for JTB

Gene summary

Gene information
	Species	Human
	Gene symbol	JTB
	Gene ID	10899
	Gene name	jumping translocation breakpoint
	Synonyms	HJTB\|HSPC222\|PAR\|hJT
	Cytomap	1q21.3
	Type of gene	protein-coding
	Description	protein JTBjumping translocation breakpoint proteinprostate androgen-regulated protein
	Modification date	20220513
	UniProtAcc	O76095

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
JTB	GO:0000281	mitotic cytokinesis	21873635	Process
JTB	GO:0005737	cytoplasm	21873635	Component
JTB	GO:0005813	centrosome	21873635	Component
JTB	GO:0005819	spindle	21873635	Component
JTB	GO:0030496	midbody	21873635	Component

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Spatial pattern events for JTB

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
JTB	Human	Brain	rep_10	33558695	8.72e-08
JTB	Human	Bladder	rep_2	34385456	1.26e-13
JTB	Human	Intestine	rep_colon1	34417225	1.95e-15
JTB	Human	Intestine	rep_colon2	34417225	8.12e-16
JTB	Human	Intestine	rep_colon3	34417225	1.82e-15
JTB	Human	Intestine	rep_colon4	34417225	1.14e-15
JTB	Human	Liver	rep_liver1	34417225	1.08e-15
JTB	Human	Liver	rep_liver2	34417225	6.98e-16
JTB	Human	Liver	rep_liver4	34417225	7.71e-16
JTB	Human	Intestine	A1	33406409	8.18e-09
JTB	Human	Uterus	rep_2	34857954	2.55e-15
JTB	Human	Uterus	rep_3	34857954	1.66e-15
JTB	Human	Breast	1160920F	34493872	1.48e-15
JTB	Human	Breast	CID4290	34493872	3.12e-10
JTB	Human	Breast	CID4465	34493872	4.85e-15
JTB	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_10_H&E
Bladder_rep_2_H&E
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID4465_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has JTB envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
JTB	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Brain	rep_1	8.7e-71
JTB	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Brain	rep_1	8.7e-71
JTB	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	2.8e-23
JTB	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Brain	rep_1	4.4e-07
JTB	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	2.8e-23
JTB	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	2.8e-23
JTB	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	7.4e-34
JTB	GOBP_Regulation_Of_Protein_Modification_Process	Human	Brain	rep_1	7.4e-34
JTB	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Brain	rep_1	7.4e-34
JTB	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Liver	rep_1	2.1e-52
JTB	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Liver	rep_1	2.1e-52
JTB	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
JTB	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Liver	rep_1	1.1e-67
JTB	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
JTB	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
JTB	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
JTB	GOBP_Regulation_Of_Protein_Modification_Process	Human	Liver	rep_1	1.0e-70
JTB	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Liver	rep_1	1.0e-70
JTB	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	rep_colon2	2.3e-37
JTB	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	rep_colon2	2.3e-37
JTB	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	rep_colon4	1.2e-51
JTB	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
JTB	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
JTB	GOBP_Cell_Division	Human	Intestine	A3	2.7e-10
JTB	GOBP_Cytokinesis	Human	Intestine	A3	5.4e-10
JTB	GOBP_Cytoskeleton_Dependent_Cytokinesis	Human	Intestine	A3	3.5e-15
JTB	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
JTB	GOBP_Mitotic_Cytokinesis	Human	Intestine	A3	3.4e-12
JTB	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Intestine	A3	7.7e-16
JTB	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Intestine	A3	2.1e-13
JTB	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	7.8e-15
JTB	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Intestine	A3	5.0e-14
JTB	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	9.1e-12
JTB	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	2.0e-08
JTB	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Intestine	A3	2.1e-11
JTB	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	1.5e-11
JTB	GOBP_Regulation_Of_Protein_Modification_Process	Human	Intestine	A3	1.1e-14
JTB	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Intestine	A3	8.8e-11
JTB	GOBP_Regulation_Of_Transferase_Activity	Human	Intestine	A3	3.9e-10
JTB	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Intestine	A8	1.1e-12
JTB	GOBP_Cell_Division	Human	Pancreas	PDAC-B-st1	5.8e-05
JTB	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Pancreas	PDAC-B-st1	8.9e-05
JTB	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_29	2.8e-06
JTB	GOBP_Positive_Regulation_Of_Catalytic_Activity	Human	Breast	rep_5	1.9e-12
JTB	GOBP_Positive_Regulation_Of_Molecular_Function	Human	Breast	rep_5	7.4e-10
JTB	GOBP_Positive_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	5.9e-12
JTB	GOBP_Positive_Regulation_Of_Protein_Metabolic_Process	Human	Breast	rep_5	2.6e-04
JTB	GOBP_Positive_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	3.0e-10
JTB	GOBP_Positive_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	1.0e-15
JTB	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	2.5e-06
JTB	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_5	1.4e-06
JTB	GOBP_Regulation_Of_Protein_Modification_Process	Human	Breast	rep_5	9.1e-07
JTB	GOBP_Regulation_Of_Protein_Phosphorylation	Human	Breast	rep_5	5.8e-14
JTB	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
JTB	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
JTB	GOBP_Cell_Division	Human	Breast	rep_6	8.2e-07
JTB	GOBP_Cytokinesis	Human	Breast	rep_6	1.4e-06
JTB	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
JTB	GOBP_Mitotic_Cytokinesis	Human	Breast	rep_6	1.2e-04
JTB	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Breast	rep_6	1.5e-05
JTB	GOBP_Positive_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	3.2e-05
JTB	GOBP_Regulation_Of_Transferase_Activity	Human	Breast	rep_6	4.6e-05
JTB	GOBP_Cytokinesis	Human	Skin	P5_rep1	9.4e-11
JTB	GOBP_Cytoskeleton_Dependent_Cytokinesis	Human	Skin	P5_rep1	6.7e-08
JTB	GOBP_Mitotic_Cytokinesis	Human	Skin	P5_rep3	1.1e-08
JTB	GOBP_Positive_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	7.4e-09
JTB	GOBP_Regulation_Of_Protein_Kinase_Activity	Human	Lung	rep_1	3.2e-09

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JTB function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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JTB function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for JTB envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for JTB

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for JTB

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source