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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CPSF4 (spascer ID:10898)

Gene summary for CPSF4

Gene summary

Gene information
	Species	Human
	Gene symbol	CPSF4
	Gene ID	10898
	Gene name	cleavage and polyadenylation specific factor 4
	Synonyms	CPSF30\|NAR\|NEB-1\|NEB1
	Cytomap	7q22.1
	Type of gene	protein-coding
	Description	cleavage and polyadenylation specificity factor subunit 4CPSF 30 kDa subunitNS1 effector domain-binding protein 1cleavage and polyadenylation specific factor 4, 30kDacleavage and polyadenylation specificity factor 30 kDa subunitno arches homologno a
	Modification date	20220513
	UniProtAcc	O95639

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CPSF4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	21873635	Component
CPSF4	GO:0098789	pre-mRNA cleavage required for polyadenylation	21873635	Process

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Spatial pattern events for CPSF4

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CPSF4	Human	Liver	rep_liver1	34417225	2.29e-09
CPSF4	Human	Liver	rep_liver2	34417225	6.98e-16
CPSF4	Human	Breast	CID44971	34493872	3.29e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has CPSF4 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CPSF4	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Intestine	A3	3.9e-17
CPSF4	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
CPSF4	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
CPSF4	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
CPSF4	GOBP_Establishment_Of_Rna_Localization	Human	Intestine	A3	9.7e-11
CPSF4	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
CPSF4	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
CPSF4	GOBP_Mrna_3_End_Processing	Human	Intestine	A3	4.9e-12
CPSF4	GOBP_Mrna_Export_From_Nucleus	Human	Intestine	A3	9.9e-15
CPSF4	GOBP_Mrna_Metabolic_Process	Human	Intestine	A3	7.7e-20
CPSF4	GOBP_Mrna_Processing	Human	Intestine	A3	4.9e-17
CPSF4	GOBP_Mrna_Transport	Human	Intestine	A3	6.6e-09
CPSF4	GOBP_Ncrna_Metabolic_Process	Human	Intestine	A3	8.6e-07
CPSF4	GOBP_Nuclear_Export	Human	Intestine	A3	3.6e-07
CPSF4	GOBP_Nuclear_Transport	Human	Intestine	A3	5.6e-10
CPSF4	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Human	Intestine	A3	1.9e-08
CPSF4	GOBP_Nucleobase_Containing_Compound_Transport	Human	Intestine	A3	2.5e-11
CPSF4	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
CPSF4	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Intestine	A3	1.6e-13
CPSF4	GOBP_Regulation_Of_Mrna_Processing	Human	Intestine	A3	1.2e-11
CPSF4	GOBP_Rna_3_End_Processing	Human	Intestine	A3	9.2e-07
CPSF4	GOBP_Rna_Export_From_Nucleus	Human	Intestine	A3	3.3e-10
CPSF4	GOBP_Rna_Localization	Human	Intestine	A3	1.4e-08
CPSF4	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Intestine	A3	2.3e-07
CPSF4	GOBP_Rna_Processing	Human	Intestine	A3	3.9e-09
CPSF4	GOBP_Rna_Splicing	Human	Intestine	A3	3.3e-19
CPSF4	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Intestine	A3	2.2e-12
CPSF4	GOBP_Trna_Metabolic_Process	Human	Intestine	A3	2.5e-12
CPSF4	GOBP_Trna_Processing	Human	Intestine	A3	1.6e-08
CPSF4	GOBP_Dna_Templated_Transcription_Termination	Human	Intestine	A8	1.4e-07
CPSF4	GOBP_Mrna_Cleavage	Human	Intestine	A8	5.7e-07
CPSF4	GOBP_Mrna_Cleavage_Involved_In_Mrna_Processing	Human	Intestine	A8	4.4e-07
CPSF4	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Human	Intestine	A8	8.1e-26
CPSF4	GOBP_Mrna_Cleavage	Human	Pancreas	PDAC-B-st1	7.7e-05
CPSF4	GOBP_Mrna_Metabolic_Process	Human	Pancreas	PDAC-B-st1	2.6e-05
CPSF4	GOBP_Rna_Export_From_Nucleus	Human	Pancreas	PDAC-B-st1	6.7e-05
CPSF4	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Pancreas	PDAC-B-st1	3.3e-05
CPSF4	GOBP_Rna_Splicing	Human	Pancreas	PDAC-B-st1	1.9e-05
CPSF4	GOBP_Dna_Templated_Transcription_Termination	Human	Pancreas	PDAC-A-st2	2.1e-07
CPSF4	GOBP_Mrna_Export_From_Nucleus	Human	Pancreas	PDAC-A-st2	3.9e-08
CPSF4	GOBP_Ncrna_Processing	Human	Uterus	rep_1	4.5e-06
CPSF4	GOBP_Mrna_Cleavage_Involved_In_Mrna_Processing	Human	Uterus	rep_25	8.1e-09
CPSF4	GOBP_Nuclear_Export	Human	Uterus	rep_25	7.4e-11
CPSF4	GOBP_Nuclear_Transport	Human	Uterus	rep_25	2.3e-13
CPSF4	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
CPSF4	GOBP_Establishment_Of_Rna_Localization	Human	Uterus	rep_26	8.7e-07
CPSF4	GOBP_Mrna_Export_From_Nucleus	Human	Uterus	rep_26	3.9e-08
CPSF4	GOBP_Rna_Export_From_Nucleus	Human	Uterus	rep_26	3.8e-10
CPSF4	GOBP_Rna_Localization	Human	Uterus	rep_26	1.2e-09
CPSF4	GOBP_Rna_Splicing	Human	Uterus	rep_26	1.0e-05
CPSF4	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Human	Uterus	rep_26	4.2e-21
CPSF4	GOBP_Trna_Metabolic_Process	Human	Uterus	rep_26	9.4e-08
CPSF4	GOBP_Mrna_3_End_Processing	Human	Uterus	rep_27	5.1e-08
CPSF4	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Uterus	rep_29	4.0e-06
CPSF4	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Breast	rep_1	1.2e-30
CPSF4	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
CPSF4	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
CPSF4	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
CPSF4	GOBP_Dna_Templated_Transcription_Termination	Human	Breast	rep_6	7.8e-07
CPSF4	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
CPSF4	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
CPSF4	GOBP_Mrna_3_End_Processing	Human	Breast	rep_6	6.6e-04
CPSF4	GOBP_Mrna_Cleavage	Human	Breast	rep_6	9.8e-11
CPSF4	GOBP_Mrna_Cleavage_Involved_In_Mrna_Processing	Human	Breast	rep_6	1.0e-06
CPSF4	GOBP_Mrna_Export_From_Nucleus	Human	Breast	rep_6	1.1e-04
CPSF4	GOBP_Mrna_Metabolic_Process	Human	Breast	rep_6	3.0e-08
CPSF4	GOBP_Mrna_Processing	Human	Breast	rep_6	1.5e-06
CPSF4	GOBP_Mrna_Transport	Human	Breast	rep_6	1.9e-10
CPSF4	GOBP_Ncrna_Metabolic_Process	Human	Breast	rep_6	1.9e-04
CPSF4	GOBP_Ncrna_Processing	Human	Breast	rep_6	1.3e-05
CPSF4	GOBP_Nuclear_Export	Human	Breast	rep_6	1.4e-05
CPSF4	GOBP_Nuclear_Transport	Human	Breast	rep_6	3.1e-08
CPSF4	GOBP_Nucleic_Acid_Phosphodiester_Bond_Hydrolysis	Human	Breast	rep_6	2.6e-05
CPSF4	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
CPSF4	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Breast	rep_6	9.5e-05
CPSF4	GOBP_Regulation_Of_Mrna_Processing	Human	Breast	rep_6	2.4e-04
CPSF4	GOBP_Rna_3_End_Processing	Human	Breast	rep_6	1.8e-05
CPSF4	GOBP_Rna_Export_From_Nucleus	Human	Breast	rep_6	9.6e-09
CPSF4	GOBP_Rna_Localization	Human	Breast	rep_6	7.7e-05
CPSF4	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Breast	rep_6	2.8e-06
CPSF4	GOBP_Rna_Processing	Human	Breast	rep_6	3.5e-06
CPSF4	GOBP_Rna_Splicing	Human	Breast	rep_6	1.1e-09
CPSF4	GOBP_Rna_Splicing_Via_Endonucleolytic_Cleavage_And_Ligation	Human	Breast	rep_6	2.6e-16
CPSF4	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Human	Breast	rep_6	5.4e-08
CPSF4	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Human	Breast	rep_6	1.7e-07
CPSF4	GOBP_Trna_Metabolic_Process	Human	Breast	rep_6	3.9e-05
CPSF4	GOBP_Trna_Processing	Human	Breast	rep_6	3.5e-08
CPSF4	GOBP_Nuclear_Transport	Human	Skin	P5_rep1	5.0e-19
CPSF4	GOBP_Mrna_Metabolic_Process	Human	Skin	P5_rep3	1.8e-08
CPSF4	GOBP_Mrna_Processing	Human	Skin	P5_rep3	9.7e-09
CPSF4	GOBP_Regulation_Of_Mrna_Metabolic_Process	Human	Skin	P5_rep3	4.0e-08
CPSF4	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Skin	P9_rep2	2.5e-08
CPSF4	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
CPSF4	GOBP_Termination_Of_Rna_Polymerase_Ii_Transcription	Human	Skin	P10_rep2	7.6e-23
CPSF4	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
CPSF4	GOBP_Rna_Phosphodiester_Bond_Hydrolysis	Human	Lung	rep_1	8.8e-08
CPSF4	GOBP_Biological_Process_Involved_In_Interaction_With_Host	Human	Lung	rep_2	4.5e-08

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CPSF4 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CPSF4 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CPSF4 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CPSF4

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CPSF4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source