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Spatial pattern gene: WDR3 (spascer ID:10885) |
Gene summary for WDR3 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | WDR3 | Gene ID | 10885 |
| Gene name | WD repeat domain 3 |
| Synonyms | DIP2|UTP12 |
| Cytomap | 1p12 |
| Type of gene | protein-coding |
| Description | WD repeat-containing protein 3dJ776P7.2 (WD repeat domain 3) |
| Modification date | 20220513 |
| UniProtAcc | Q9UNX4 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| WDR3 | GO:0030490 | maturation of SSU-rRNA | 21873635 | Process |
| WDR3 | GO:0030515 | snoRNA binding | 21873635 | Function |
| WDR3 | GO:0032040 | small-subunit processome | 21873635 | Component |
| WDR3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome | 21873635 | Component |
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Spatial pattern events for WDR3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| WDR3 | Human | Liver | rep_liver1 | 34417225 | 3.57e-15 |
| WDR3 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| WDR3 | Human | Uterus | rep_3 | 34857954 | 4.02e-10 |
| WDR3 | Human | Breast | A6 | 34650042 | 1.88e-06 |
| WDR3 | Human | Breast | 1160920F | 34493872 | 4.98e-06 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_A6_H&E  |  |
Breast_1160920F_H&E  |  |
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Spatial pattern pathway has WDR3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| WDR3 | GOBP_Maturation_Of_Ssu_Rrna | Human | Intestine | A1 | 1.5e-17 |
| WDR3 | GOBP_Ribosomal_Small_Subunit_Biogenesis | Human | Intestine | A1 | 3.0e-16 |
| WDR3 | GOBP_Ribosome_Biogenesis | Human | Intestine | A1 | 6.5e-08 |
| WDR3 | GOBP_Ncrna_Metabolic_Process | Human | Intestine | A3 | 8.6e-07 |
| WDR3 | GOBP_Rna_Processing | Human | Intestine | A3 | 3.9e-09 |
| WDR3 | GOBP_Ncrna_Processing | Human | Uterus | rep_1 | 4.5e-06 |
| WDR3 | GOBP_Ribosomal_Small_Subunit_Biogenesis | Human | Uterus | rep_1 | 3.0e-06 |
| WDR3 | GOBP_Ribosome_Biogenesis | Human | Uterus | rep_1 | 9.5e-06 |
| WDR3 | GOBP_Rrna_Metabolic_Process | Human | Uterus | rep_1 | 2.4e-07 |
| WDR3 | GOBP_Maturation_Of_Ssu_Rrna | Human | Uterus | rep_26 | 1.3e-06 |
| WDR3 | GOBP_Maturation_Of_Ssu_Rrna | Human | Breast | rep_6 | 6.4e-06 |
| WDR3 | GOBP_Ncrna_Metabolic_Process | Human | Breast | rep_6 | 1.9e-04 |
| WDR3 | GOBP_Ncrna_Processing | Human | Breast | rep_6 | 1.3e-05 |
| WDR3 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Human | Breast | rep_6 | 1.3e-07 |
| WDR3 | GOBP_Ribosomal_Small_Subunit_Biogenesis | Human | Breast | rep_6 | 2.8e-07 |
| WDR3 | GOBP_Ribosome_Biogenesis | Human | Breast | rep_6 | 2.0e-06 |
| WDR3 | GOBP_Rna_Processing | Human | Breast | rep_6 | 3.5e-06 |
| WDR3 | GOBP_Rrna_Metabolic_Process | Human | Breast | rep_6 | 4.0e-06 |
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WDR3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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WDR3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for WDR3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for WDR3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for WDR3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
