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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: CFHR3 (spascer ID:10878)

Gene summary for CFHR3

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

CFHR3

Gene ID

10878

Gene namecomplement factor H related 3
SynonymsCFHL3|DOWN16|FHR-3|FHR3|HLF4
Cytomap1q31.3
Type of geneprotein-coding
Descriptioncomplement factor H-related protein 3H factor-like 4H factor-like protein 3
Modification date20220513
UniProtAcc

Q02985


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory

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Spatial pattern events for CFHR3

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
CFHR3HumanLiverrep_liver1 344172253.57e-15
CFHR3HumanLiverrep_liver2 344172251.27e-15
CFHR3HumanLiverrep_liver3 344172253.51e-15
CFHR3HumanLiverrep_liver4 344172257.71e-16

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Liver_rep_liver3_H&E
boxplot

boxplot
Liver_rep_liver4_H&E
boxplot

boxplot


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Spatial pattern pathway has CFHR3 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value

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CFHR3 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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CFHR3 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for CFHR3 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for CFHR3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CFHR3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
CFHR3C0017661IGA Glomerulonephritis1CTD_human
CFHR3C0025303Meningococcal Infections1CTD_human
CFHR3C2749604HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 11GENOMICS_ENGLAND