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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SRCAP (spascer ID:10847)

Gene summary for SRCAP

Gene summary

Gene information
	Species	Human
	Gene symbol	SRCAP
	Gene ID	10847
	Gene name	Snf2 related CREBBP activator protein
	Synonyms	DEHMBA\|DOMO1\|EAF1\|FLHS\|SWR1
	Cytomap	16p11.2
	Type of gene	protein-coding
	Description	helicase SRCAPSnf2-related CBP activator proteinSwi2/Snf2-related ATPase homolog, domino homolog 1domino homolog 2
	Modification date	20220513
	UniProtAcc	Q6ZRS2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SRCAP	GO:0000812	Swr1 complex	21873635	Component
SRCAP	GO:0016887	ATP hydrolysis activity	21873635	Function
SRCAP	GO:0042393	histone binding	21873635	Function
SRCAP	GO:0043486	histone exchange	21873635	Process

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Spatial pattern events for SRCAP

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SRCAP	Human	Intestine	rep_colon1	34417225	2.53e-14
SRCAP	Human	Liver	rep_liver1	34417225	2.02e-10
SRCAP	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has SRCAP envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SRCAP	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
SRCAP	GOBP_Chromatin_Organization	Human	Intestine	A3	3.2e-11
SRCAP	GOBP_Chromosome_Organization	Human	Intestine	A3	2.5e-13
SRCAP	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Intestine	A3	2.8e-18
SRCAP	GOBP_Nucleosome_Organization	Human	Intestine	A3	5.8e-10
SRCAP	GOBP_Peptidyl_Amino_Acid_Modification	Human	Intestine	A3	2.7e-09
SRCAP	GOBP_Peptidyl_Lysine_Modification	Human	Intestine	A3	2.8e-09
SRCAP	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
SRCAP	GOBP_Protein_Dna_Complex_Subunit_Organization	Human	Intestine	A3	5.3e-07
SRCAP	GOBP_Peptidyl_Lysine_Acetylation	Human	Intestine	A8	1.9e-08
SRCAP	GOBP_Protein_Acetylation	Human	Intestine	A8	6.7e-07
SRCAP	GOBP_Chromatin_Organization	Human	Uterus	rep_1	1.9e-06
SRCAP	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
SRCAP	GOBP_Chromosome_Organization	Human	Uterus	rep_26	1.2e-09
SRCAP	GOBP_Histone_Exchange	Human	Uterus	rep_26	1.4e-06
SRCAP	GOBP_Nucleosome_Organization	Human	Uterus	rep_26	1.6e-09
SRCAP	GOBP_Peptidyl_Lysine_Modification	Human	Uterus	rep_26	2.3e-09
SRCAP	GOBP_Protein_Dna_Complex_Subunit_Organization	Human	Uterus	rep_26	1.7e-08
SRCAP	GOBP_Peptidyl_Lysine_Acetylation	Human	Uterus	rep_29	6.7e-06
SRCAP	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
SRCAP	GOBP_Chromatin_Remodeling	Human	Breast	rep_1	1.7e-06
SRCAP	GOBP_Peptidyl_Lysine_Acetylation	Human	Breast	rep_1	4.3e-46
SRCAP	GOBP_Protein_Acetylation	Human	Breast	rep_1	3.7e-29
SRCAP	GOBP_Protein_Acylation	Human	Breast	rep_1	1.9e-23
SRCAP	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Breast	rep_5	5.3e-06
SRCAP	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
SRCAP	GOBP_Chromatin_Organization	Human	Breast	rep_6	4.3e-07
SRCAP	GOBP_Chromosome_Organization	Human	Breast	rep_6	1.1e-06
SRCAP	GOBP_Histone_Exchange	Human	Breast	rep_6	4.5e-08
SRCAP	GOBP_Nucleosome_Organization	Human	Breast	rep_6	3.8e-06
SRCAP	GOBP_Peptidyl_Amino_Acid_Modification	Human	Breast	rep_6	3.8e-05
SRCAP	GOBP_Peptidyl_Lysine_Modification	Human	Breast	rep_6	4.5e-08
SRCAP	GOBP_Protein_Dna_Complex_Subunit_Organization	Human	Breast	rep_6	1.9e-07
SRCAP	GOBP_Peptidyl_Lysine_Acetylation	Human	Skin	P5_rep1	1.5e-08
SRCAP	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
SRCAP	GOBP_Histone_Exchange	Human	Skin	P10_rep1	2.6e-15
SRCAP	GOBP_Nucleosome_Organization	Human	Skin	P10_rep2	5.3e-12
SRCAP	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10

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SRCAP function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SRCAP function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SRCAP envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SRCAP

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SRCAP

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SRCAP	C0729582	Floating-harbor syndrome	2	CTD_human;GENOMICS_ENGLAND;ORPHANET
SRCAP	C0010606	Adenoid Cystic Carcinoma	1	CTD_human
SRCAP	C1535926	Neurodevelopmental Disorders	1	CTD_human