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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SDCCAG8 (spascer ID:10806)

Gene summary for SDCCAG8

Gene summary

Gene information
	Species	Human
	Gene symbol	SDCCAG8
	Gene ID	10806
	Gene name	SHH signaling and ciliogenesis regulator SDCCAG8
	Synonyms	BBS16\|CCCAP\|CCCAP SLSN7\|HSPC085\|NPHP10\|NY-CO-8\|SLSN7\|hCCCAP
	Cytomap	1q43-q44
	Type of gene	protein-coding
	Description	serologically defined colon cancer antigen 8Bardet-Biedl syndrome 16antigen NY-CO-8centrosomal colon cancer autoantigen proteinnephrocystin 10
	Modification date	20220513
	UniProtAcc	Q86SQ7

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SDCCAG8	GO:0001764	neuron migration	21873635	Process
SDCCAG8	GO:0005813	centrosome	21873635	Component
SDCCAG8	GO:0005814	centriole	21873635	Component
SDCCAG8	GO:0030010	establishment of cell polarity	21873635	Process
SDCCAG8	GO:0031023	microtubule organizing center organization	21873635	Process
SDCCAG8	GO:0035148	tube formation	21873635	Process

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Spatial pattern events for SDCCAG8

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SDCCAG8	Human	Intestine	rep_colon1	34417225	3.42e-15
SDCCAG8	Human	Liver	rep_liver1	34417225	3.13e-12
SDCCAG8	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Liver_rep_liver1_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has SDCCAG8 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SDCCAG8	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
SDCCAG8	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
SDCCAG8	GOBP_Neurogenesis	Human	Brain	rep_1	7.4e-34
SDCCAG8	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Brain	rep_4	4.1e-17
SDCCAG8	GOBP_Tube_Development	Human	Brain	rep_4	4.1e-17
SDCCAG8	GOBP_Tube_Morphogenesis	Human	Brain	rep_4	4.1e-17
SDCCAG8	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Liver	rep_1	6.0e-76
SDCCAG8	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
SDCCAG8	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
SDCCAG8	GOBP_Neurogenesis	Human	Liver	rep_1	1.0e-70
SDCCAG8	GOBP_Tube_Development	Human	Liver	rep_1	6.0e-76
SDCCAG8	GOBP_Tube_Morphogenesis	Human	Liver	rep_1	6.0e-76
SDCCAG8	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
SDCCAG8	GOBP_Tube_Development	Human	Intestine	rep_colon4	1.9e-09
SDCCAG8	GOBP_Tube_Morphogenesis	Human	Intestine	rep_colon4	1.9e-09
SDCCAG8	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
SDCCAG8	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
SDCCAG8	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
SDCCAG8	GOBP_Cell_Cycle_Phase_Transition	Human	Intestine	A3	3.5e-07
SDCCAG8	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
SDCCAG8	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
SDCCAG8	GOBP_Cell_Projection_Assembly	Human	Intestine	A3	4.9e-09
SDCCAG8	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
SDCCAG8	GOBP_Cilium_Organization	Human	Intestine	A3	7.4e-11
SDCCAG8	GOBP_Establishment_Of_Cell_Polarity	Human	Intestine	A3	1.0e-09
SDCCAG8	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Human	Intestine	A3	8.2e-09
SDCCAG8	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
SDCCAG8	GOBP_Membrane_Docking	Human	Intestine	A3	1.0e-09
SDCCAG8	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
SDCCAG8	GOBP_Microtubule_Cytoskeleton_Organization	Human	Intestine	A3	4.8e-11
SDCCAG8	GOBP_Microtubule_Organizing_Center_Organization	Human	Intestine	A3	2.8e-12
SDCCAG8	GOBP_Mitotic_Cell_Cycle	Human	Intestine	A3	1.8e-12
SDCCAG8	GOBP_Neurogenesis	Human	Intestine	A3	6.4e-14
SDCCAG8	GOBP_Organelle_Localization	Human	Intestine	A3	5.1e-12
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle	Human	Intestine	A3	1.6e-08
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Intestine	A3	2.6e-08
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Intestine	A3	1.1e-15
SDCCAG8	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Intestine	A3	4.1e-07
SDCCAG8	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
SDCCAG8	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
SDCCAG8	GOBP_Regulation_Of_Cilium_Assembly	Human	Intestine	A3	3.3e-09
SDCCAG8	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Intestine	A3	1.5e-08
SDCCAG8	GOBP_Regulation_Of_Organelle_Assembly	Human	Intestine	A3	9.7e-21
SDCCAG8	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
SDCCAG8	GOBP_Tube_Development	Human	Intestine	A3	7.6e-08
SDCCAG8	GOBP_Tube_Morphogenesis	Human	Intestine	A3	9.4e-07
SDCCAG8	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Intestine	A8	3.3e-08
SDCCAG8	GOBP_Cell_Cycle_G2_M_Phase_Transition	Human	Intestine	A8	4.0e-09
SDCCAG8	GOBP_Regulation_Of_Cilium_Assembly	Human	Pancreas	PDAC-A-st2	2.2e-06
SDCCAG8	GOBP_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	1.9e-06
SDCCAG8	GOBP_Membrane_Docking	Human	Uterus	rep_26	2.2e-13
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Uterus	rep_26	9.3e-07
SDCCAG8	GOBP_Regulation_Of_Cilium_Assembly	Human	Uterus	rep_26	3.5e-10
SDCCAG8	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Uterus	rep_26	2.5e-07
SDCCAG8	GOBP_Regulation_Of_Organelle_Assembly	Human	Uterus	rep_26	2.0e-06
SDCCAG8	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Human	Breast	rep_1	1.9e-98
SDCCAG8	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
SDCCAG8	GOBP_Cell_Projection_Assembly	Human	Breast	rep_1	1.9e-26
SDCCAG8	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
SDCCAG8	GOBP_Cytoskeleton_Organization	Human	Breast	rep_1	1.3e-22
SDCCAG8	GOBP_Establishment_Of_Cell_Polarity	Human	Breast	rep_1	3.9e-06
SDCCAG8	GOBP_Establishment_Or_Maintenance_Of_Cell_Polarity	Human	Breast	rep_1	1.1e-43
SDCCAG8	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
SDCCAG8	GOBP_Membrane_Docking	Human	Breast	rep_1	1.6e-56
SDCCAG8	GOBP_Neurogenesis	Human	Breast	rep_1	8.0e-11
SDCCAG8	GOBP_Organelle_Localization	Human	Breast	rep_1	1.8e-08
SDCCAG8	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Breast	rep_1	6.5e-29
SDCCAG8	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
SDCCAG8	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
SDCCAG8	GOBP_Regulation_Of_Cilium_Assembly	Human	Breast	rep_1	8.0e-07
SDCCAG8	GOBP_Regulation_Of_Organelle_Assembly	Human	Breast	rep_1	1.0e-12
SDCCAG8	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
SDCCAG8	GOBP_Tube_Development	Human	Breast	rep_1	3.8e-32
SDCCAG8	GOBP_Tube_Morphogenesis	Human	Breast	rep_1	2.7e-34
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle	Human	Breast	rep_5	3.7e-04
SDCCAG8	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
SDCCAG8	GOBP_Cell_Cycle_G2_M_Phase_Transition	Human	Breast	rep_6	3.0e-12
SDCCAG8	GOBP_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	4.9e-09
SDCCAG8	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
SDCCAG8	GOBP_Cilium_Organization	Human	Breast	rep_6	3.8e-08
SDCCAG8	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
SDCCAG8	GOBP_Microtubule_Cytoskeleton_Organization	Human	Breast	rep_6	1.9e-04
SDCCAG8	GOBP_Microtubule_Organizing_Center_Organization	Human	Breast	rep_6	1.2e-05
SDCCAG8	GOBP_Mitotic_Cell_Cycle	Human	Breast	rep_6	3.2e-09
SDCCAG8	GOBP_Organelle_Assembly	Human	Breast	rep_6	2.3e-07
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Human	Breast	rep_6	7.4e-13
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle_Phase_Transition	Human	Breast	rep_6	2.7e-07
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle_Process	Human	Breast	rep_6	6.1e-08
SDCCAG8	GOBP_Regulation_Of_Mitotic_Cell_Cycle	Human	Breast	rep_6	4.6e-09
SDCCAG8	GOBP_Tube_Formation	Human	Breast	rep_6	8.9e-04
SDCCAG8	GOBP_Microtubule_Organizing_Center_Organization	Human	Skin	P2_rep1	3.1e-08
SDCCAG8	GOBP_Organelle_Localization	Human	Skin	P5_rep1	2.1e-13
SDCCAG8	GOBP_Regulation_Of_Cell_Cycle_G2_M_Phase_Transition	Human	Skin	P5_rep1	2.0e-09
SDCCAG8	GOBP_Establishment_Of_Cell_Polarity	Human	Skin	P5_rep3	1.8e-12
SDCCAG8	GOBP_Cytoskeleton_Organization	Human	Skin	P9_rep3	3.1e-12

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SDCCAG8 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SDCCAG8 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SDCCAG8 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SDCCAG8

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SDCCAG8

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
SDCCAG8	C3150877	SENIOR-LOKEN SYNDROME 7	3	GENOMICS_ENGLAND
SDCCAG8	C3889474	BARDET-BIEDL SYNDROME 16	3	CTD_human;GENOMICS_ENGLAND
SDCCAG8	C0403553	Renal dysplasia and retinal aplasia (disorder)	2	GENOMICS_ENGLAND;ORPHANET
SDCCAG8	C0752166	Bardet-Biedl Syndrome	2	GENOMICS_ENGLAND;ORPHANET
SDCCAG8	C0022679	Cystic kidney	1	CTD_human
SDCCAG8	C0035309	Retinal Diseases	1	CTD_human
SDCCAG8	C0036341	Schizophrenia	1	PSYGENET
SDCCAG8	C1691228	Cystic Kidney Diseases	1	CTD_human
SDCCAG8	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND