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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: SEC24A (spascer ID:10802)

Gene summary for SEC24A

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

SEC24A

Gene ID

10802

Gene nameSEC24 homolog A, COPII coat complex component
Synonyms-
Cytomap5q31.1
Type of geneprotein-coding
Descriptionprotein transport protein Sec24ASEC24 family, member ASEC24 related gene family, member ASEC24-related protein A
Modification date20220513
UniProtAcc

O95486


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
SEC24A

GO:0000149

SNARE binding

21873635

Function
SEC24A

GO:0008270

zinc ion binding

21873635

Function
SEC24A

GO:0030127

COPII vesicle coat

21873635

Component
SEC24A

GO:0070971

endoplasmic reticulum exit site

21873635

Component
SEC24A

GO:0090110

COPII-coated vesicle cargo loading

21873635

Process

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Spatial pattern events for SEC24A

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
SEC24AHumanLiverrep_liver1 344172251.08e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot


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Spatial pattern pathway has SEC24A envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
SEC24AGOBP_Cellular_Macromolecule_LocalizationHumanIntestineA3 1.7e-09
SEC24AGOBP_Copii_Coated_Vesicle_BuddingHumanIntestineA3 3.5e-11
SEC24AGOBP_Establishment_Of_Organelle_LocalizationHumanIntestineA3 9.7e-13
SEC24AGOBP_Establishment_Of_Protein_LocalizationHumanIntestineA3 5.0e-10
SEC24AGOBP_Golgi_Vesicle_TransportHumanIntestineA3 9.2e-10
SEC24AGOBP_Intracellular_Protein_TransportHumanIntestineA3 4.8e-12
SEC24AGOBP_Intracellular_TransportHumanIntestineA3 7.6e-15
SEC24AGOBP_Membrane_OrganizationHumanIntestineA3 2.7e-18
SEC24AGOBP_Organelle_LocalizationHumanIntestineA3 5.1e-12
SEC24AGOBP_Vesicle_LocalizationHumanIntestineA3 1.3e-07
SEC24AGOBP_Vesicle_OrganizationHumanIntestineA3 3.0e-15
SEC24AGOBP_Vesicle_TargetingHumanIntestineA3 4.2e-07
SEC24AGOBP_Antigen_Processing_And_PresentationHumanIntestineA8 1.7e-13
SEC24AGOBP_Antigen_Processing_And_Presentation_Of_Peptide_AntigenHumanIntestineA8 8.9e-10
SEC24AGOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen_Via_Mhc_Class_IHumanIntestineA8 6.4e-13
SEC24AGOBP_Copii_Coated_Vesicle_Cargo_LoadingHumanIntestineA8 1.9e-07
SEC24AGOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_TransportHumanIntestineA8 2.4e-10
SEC24AGOBP_Vesicle_Budding_From_MembraneHumanIntestineA8 4.3e-15
SEC24AGOBP_Vesicle_Targeting_To_From_Or_Within_GolgiHumanIntestineA8 2.6e-12
SEC24AGOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_IiHumanPancreasPDAC-B-st1 7.1e-05
SEC24AGOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_TransportHumanPancreasPDAC-B-st1 9.2e-05
SEC24AGOBP_Copii_Coated_Vesicle_Cargo_LoadingHumanPancreasPDAC-A-st2 1.6e-05
SEC24AGOBP_Copii_Coated_Vesicle_Cargo_LoadingHumanUterusrep_1 5.5e-06
SEC24AGOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen_Via_Mhc_Class_IHumanUterusrep_26 2.2e-06
SEC24AGOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_IiHumanUterusrep_26 7.6e-06
SEC24AGOBP_Copii_Coated_Vesicle_BuddingHumanUterusrep_26 2.0e-14
SEC24AGOBP_Golgi_Vesicle_TransportHumanUterusrep_26 3.4e-14
SEC24AGOBP_Vesicle_Cargo_LoadingHumanUterusrep_26 7.5e-06
SEC24AGOBP_Antigen_Processing_And_Presentation_Of_Peptide_AntigenHumanUterusrep_28 2.7e-08
SEC24AGOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_TransportHumanUterusrep_29 6.3e-06
SEC24AGOBP_Cellular_Macromolecule_LocalizationHumanBreastrep_1 3.7e-09
SEC24AGOBP_Establishment_Of_Organelle_LocalizationHumanBreastrep_1 6.5e-08
SEC24AGOBP_Establishment_Of_Protein_LocalizationHumanBreastrep_1 7.2e-05
SEC24AGOBP_Organelle_LocalizationHumanBreastrep_1 1.8e-08
SEC24AGOBP_Vesicle_Budding_From_MembraneHumanBreastrep_1 1.7e-07
SEC24AGOBP_Vesicle_LocalizationHumanBreastrep_1 7.0e-11
SEC24AGOBP_Vesicle_OrganizationHumanBreastrep_1 8.3e-15
SEC24AGOBP_Copii_Coated_Vesicle_BuddingHumanBreastrep_6 2.0e-11
SEC24AGOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_TransportHumanBreastrep_6 4.9e-08
SEC24AGOBP_Golgi_Vesicle_TransportHumanBreastrep_6 2.0e-08
SEC24AGOBP_Intracellular_Protein_TransportHumanBreastrep_6 6.4e-12
SEC24AGOBP_Intracellular_TransportHumanBreastrep_6 1.3e-08
SEC24AGOBP_Vesicle_Cargo_LoadingHumanBreastrep_6 7.9e-04
SEC24AGOBP_Vesicle_TargetingHumanBreastrep_6 3.4e-09
SEC24AGOBP_Vesicle_Targeting_To_From_Or_Within_GolgiHumanBreastrep_6 6.9e-08
SEC24AGOBP_Organelle_LocalizationHumanSkinP5_rep1 2.1e-13
SEC24AGOBP_Vesicle_LocalizationHumanSkinP5_rep1 2.7e-08
SEC24AGOBP_Vesicle_OrganizationHumanSkinP5_rep1 2.3e-09
SEC24AGOBP_Copii_Coated_Vesicle_Cargo_LoadingHumanSkinP10_rep3 2.8e-16
SEC24AGOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_IiHumanLungrep_2 1.2e-07

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SEC24A function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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SEC24A function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for SEC24A envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for SEC24A

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SEC24A

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource