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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SEPTIN9 (spascer ID:10801)

Gene summary for SEPTIN9

Gene summary

Gene information
	Species	Human
	Gene symbol	SEPTIN9
	Gene ID	10801
	Gene name	septin 9
	Synonyms	AF17q25\|MSF\|MSF1\|NAPB\|PNUTL4\|SEPT9\|SINT1\|SeptD1
	Cytomap	17q25.3
	Type of gene	protein-coding
	Description	septin-9MLL septin-like fusion protein MSF-AOv/Br septinovarian/breast septinseptin D1
	Modification date	20220513
	UniProtAcc	Q9UHD8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SEPTIN9	GO:0003924	GTPase activity	21873635	Function
SEPTIN9	GO:0005940	septin ring	21873635	Component
SEPTIN9	GO:0015630	microtubule cytoskeleton	21873635	Component
SEPTIN9	GO:0031105	septin complex	21873635	Component
SEPTIN9	GO:0032153	cell division site	21873635	Component
SEPTIN9	GO:0034613	cellular protein localization	21873635	Process
SEPTIN9	GO:0060090	molecular adaptor activity	21873635	Function
SEPTIN9	GO:0061640	cytoskeleton-dependent cytokinesis	21873635	Process

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Spatial pattern events for SEPTIN9

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SEPTIN9	Human	Intestine	rep_colon1	34417225	1.95e-15
SEPTIN9	Human	Intestine	rep_colon2	34417225	8.12e-16
SEPTIN9	Human	Intestine	rep_colon3	34417225	1.80e-09
SEPTIN9	Human	Liver	rep_liver1	34417225	1.08e-15
SEPTIN9	Human	Liver	rep_liver2	34417225	6.98e-16
SEPTIN9	Human	Liver	rep_liver4	34417225	1.39e-15
SEPTIN9	Human	Breast	1160920F	34493872	1.48e-15
SEPTIN9	Human	Lung	rep_1	35355018	2.85e-12

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Breast_1160920F_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has SEPTIN9 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SEPTIN9	GOBP_Cell_Cycle	Human	Intestine	A3	2.7e-11
SEPTIN9	GOBP_Cell_Cycle_Process	Human	Intestine	A3	2.7e-14
SEPTIN9	GOBP_Cell_Division	Human	Intestine	A3	2.7e-10
SEPTIN9	GOBP_Cell_Projection_Assembly	Human	Intestine	A3	4.9e-09
SEPTIN9	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
SEPTIN9	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
SEPTIN9	GOBP_Cilium_Organization	Human	Intestine	A3	7.4e-11
SEPTIN9	GOBP_Cytokinesis	Human	Intestine	A3	5.4e-10
SEPTIN9	GOBP_Cytoskeleton_Dependent_Cytokinesis	Human	Intestine	A3	3.5e-15
SEPTIN9	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	1.2e-09
SEPTIN9	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	1.9e-13
SEPTIN9	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Intestine	A3	3.8e-12
SEPTIN9	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.7e-13
SEPTIN9	GOBP_Positive_Regulation_Of_Plasma_Membrane_Bounded_Cell_Projection_Assembly	Human	Intestine	A3	3.6e-08
SEPTIN9	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Intestine	A3	4.1e-07
SEPTIN9	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Intestine	A3	7.0e-08
SEPTIN9	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
SEPTIN9	GOBP_Regulation_Of_Cilium_Assembly	Human	Intestine	A3	3.3e-09
SEPTIN9	GOBP_Regulation_Of_Organelle_Assembly	Human	Intestine	A3	9.7e-21
SEPTIN9	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
SEPTIN9	GOBP_Non_Motile_Cilium_Assembly	Human	Intestine	A8	3.4e-11
SEPTIN9	GOBP_Positive_Regulation_Of_Cilium_Assembly	Human	Intestine	A8	9.2e-11
SEPTIN9	GOBP_Positive_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Intestine	A8	2.1e-23
SEPTIN9	GOBP_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Intestine	A8	6.7e-16
SEPTIN9	GOBP_Cell_Division	Human	Pancreas	PDAC-B-st1	5.8e-05
SEPTIN9	GOBP_Positive_Regulation_Of_Cilium_Assembly	Human	Pancreas	PDAC-A-st2	6.4e-05
SEPTIN9	GOBP_Regulation_Of_Cilium_Assembly	Human	Pancreas	PDAC-A-st2	2.2e-06
SEPTIN9	GOBP_Positive_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Uterus	rep_25	1.4e-12
SEPTIN9	GOBP_Non_Motile_Cilium_Assembly	Human	Uterus	rep_26	2.4e-08
SEPTIN9	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Uterus	rep_26	1.2e-06
SEPTIN9	GOBP_Regulation_Of_Cilium_Assembly	Human	Uterus	rep_26	3.5e-10
SEPTIN9	GOBP_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Uterus	rep_26	2.4e-07
SEPTIN9	GOBP_Regulation_Of_Organelle_Assembly	Human	Uterus	rep_26	2.0e-06
SEPTIN9	GOBP_Cell_Projection_Assembly	Human	Breast	rep_1	1.9e-26
SEPTIN9	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
SEPTIN9	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
SEPTIN9	GOBP_Positive_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	1.6e-25
SEPTIN9	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	3.5e-04
SEPTIN9	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Human	Breast	rep_1	1.3e-17
SEPTIN9	GOBP_Positive_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Breast	rep_1	7.1e-14
SEPTIN9	GOBP_Positive_Regulation_Of_Organelle_Assembly	Human	Breast	rep_1	1.4e-54
SEPTIN9	GOBP_Regulation_Of_Cell_Projection_Assembly	Human	Breast	rep_1	6.5e-29
SEPTIN9	GOBP_Regulation_Of_Cell_Projection_Organization	Human	Breast	rep_1	3.8e-16
SEPTIN9	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
SEPTIN9	GOBP_Regulation_Of_Cilium_Assembly	Human	Breast	rep_1	8.0e-07
SEPTIN9	GOBP_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Breast	rep_1	5.8e-35
SEPTIN9	GOBP_Regulation_Of_Organelle_Assembly	Human	Breast	rep_1	1.0e-12
SEPTIN9	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
SEPTIN9	GOBP_Cell_Cycle	Human	Breast	rep_6	3.4e-09
SEPTIN9	GOBP_Cell_Cycle_Process	Human	Breast	rep_6	6.7e-09
SEPTIN9	GOBP_Cell_Division	Human	Breast	rep_6	8.2e-07
SEPTIN9	GOBP_Cilium_Organization	Human	Breast	rep_6	3.8e-08
SEPTIN9	GOBP_Cytokinesis	Human	Breast	rep_6	1.4e-06
SEPTIN9	GOBP_Organelle_Assembly	Human	Breast	rep_6	2.3e-07
SEPTIN9	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Breast	rep_6	7.3e-09
SEPTIN9	GOBP_Cytokinesis	Human	Skin	P5_rep1	9.4e-11
SEPTIN9	GOBP_Cytoskeleton_Dependent_Cytokinesis	Human	Skin	P5_rep1	6.7e-08
SEPTIN9	GOBP_Positive_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Skin	P5_rep3	3.8e-10
SEPTIN9	GOBP_Positive_Regulation_Of_Organelle_Organization	Human	Skin	P5_rep3	4.1e-08
SEPTIN9	GOBP_Regulation_Of_Non_Motile_Cilium_Assembly	Human	Skin	P5_rep3	2.9e-11

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SEPTIN9 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SEPTIN9 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SEPTIN9 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SEPTIN9

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SEPTIN9

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source