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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

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Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: ZBTB6 (spascer ID:10773)

Gene summary for ZBTB6

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

ZBTB6

Gene ID

10773

Gene namezinc finger and BTB domain containing 6
SynonymsZID|ZNF482
Cytomap9q33.2
Type of geneprotein-coding
Descriptionzinc finger and BTB domain-containing protein 6zinc finger protein 482zinc finger protein with interaction domain
Modification date20220513
UniProtAcc

Q15916


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
ZBTB6

GO:0000978

RNA polymerase II cis-regulatory region sequence-specific DNA binding

21873635

Function
ZBTB6

GO:0001227

DNA-binding transcription repressor activity, RNA polymerase II-specific

21873635

Function
ZBTB6

GO:0005654

nucleoplasm

21873635

Component
ZBTB6

GO:0006357

regulation of transcription by RNA polymerase II

21873635

Process

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Spatial pattern events for ZBTB6

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
ZBTB6HumanLiverrep_liver1 344172251.01e-09

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Liver_rep_liver1_H&E
boxplot

boxplot


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Spatial pattern pathway has ZBTB6 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
ZBTB6GOBP_Negative_Regulation_Of_Biosynthetic_ProcessHumanIntestineA3 5.9e-17
ZBTB6GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanIntestineA3 7.7e-14
ZBTB6GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiHumanIntestineA3 1.9e-15
ZBTB6GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanUterusrep_26 2.1e-06
ZBTB6GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiHumanUterusrep_26 6.2e-13
ZBTB6GOBP_Negative_Regulation_Of_Biosynthetic_ProcessHumanBreastrep_6 2.6e-08
ZBTB6GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessHumanBreastrep_6 3.5e-08
ZBTB6GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiHumanBreastrep_6 8.2e-08

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ZBTB6 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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ZBTB6 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for ZBTB6 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for ZBTB6

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ZBTB6

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource