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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: NUP50 (spascer ID:10762)

Gene summary for NUP50

Gene summary

Gene information
	Species	Human
	Gene symbol	NUP50
	Gene ID	10762
	Gene name	nucleoporin 50
	Synonyms	NPAP60\|NPAP60L
	Cytomap	22q13.31
	Type of gene	protein-coding
	Description	nuclear pore complex protein Nup5050 kDa nucleoporinnuclear pore-associated protein 60Lnucleoporin 50kDnucleoporin 50kDanucleoporin Nup50
	Modification date	20220513
	UniProtAcc	Q9UKX7

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
NUP50	GO:0006606	protein import into nucleus	21873635	Process

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Spatial pattern events for NUP50

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
NUP50	Human	Intestine	rep_colon2	34417225	8.12e-16
NUP50	Human	Liver	rep_liver1	34417225	1.08e-15
NUP50	Human	Liver	rep_liver2	34417225	2.49e-15
NUP50	Human	Uterus	rep_2	34857954	3.02e-06
NUP50	Human	Uterus	rep_3	34857954	3.03e-08
NUP50	Human	Lung	rep_1	35355018	2.03e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon2_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has NUP50 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
NUP50	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Brain	rep_1	7.4e-34
NUP50	GOBP_Regulation_Of_Response_To_Stress	Human	Brain	rep_1	4.6e-05
NUP50	GOBP_Trna_Transport	Human	Brain	st	8.6e-07
NUP50	GOBP_Atp_Metabolic_Process	Human	Bladder	rep_4	3.6e-11
NUP50	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Bladder	rep_4	3.4e-12
NUP50	GOBP_Regulation_Of_Atp_Metabolic_Process	Human	Bladder	rep_4	1.1e-11
NUP50	GOBP_Regulation_Of_Nucleotide_Metabolic_Process	Human	Bladder	rep_4	1.1e-12
NUP50	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Liver	rep_1	1.0e-70
NUP50	GOBP_Regulation_Of_Response_To_Stress	Human	Liver	rep_1	5.3e-67
NUP50	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	rep_colon4	2.2e-52
NUP50	GOBP_Trna_Transport	Human	Intestine	A1	1.1e-13
NUP50	GOBP_Atp_Metabolic_Process	Human	Intestine	A3	7.9e-14
NUP50	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
NUP50	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
NUP50	GOBP_Carbohydrate_Metabolic_Process	Human	Intestine	A3	4.1e-08
NUP50	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
NUP50	GOBP_Cellular_Response_To_Heat	Human	Intestine	A3	2.1e-21
NUP50	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
NUP50	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Intestine	A3	3.8e-08
NUP50	GOBP_Establishment_Of_Rna_Localization	Human	Intestine	A3	9.7e-11
NUP50	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Intestine	A3	4.3e-14
NUP50	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
NUP50	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
NUP50	GOBP_Mrna_Export_From_Nucleus	Human	Intestine	A3	9.9e-15
NUP50	GOBP_Mrna_Transport	Human	Intestine	A3	6.6e-09
NUP50	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Intestine	A3	2.8e-18
NUP50	GOBP_Nuclear_Export	Human	Intestine	A3	3.6e-07
NUP50	GOBP_Nuclear_Transport	Human	Intestine	A3	5.6e-10
NUP50	GOBP_Nucleobase_Containing_Compound_Transport	Human	Intestine	A3	2.5e-11
NUP50	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Intestine	A3	9.9e-10
NUP50	GOBP_Organophosphate_Metabolic_Process	Human	Intestine	A3	4.4e-13
NUP50	GOBP_Peptidyl_Amino_Acid_Modification	Human	Intestine	A3	2.7e-09
NUP50	GOBP_Peptidyl_Lysine_Modification	Human	Intestine	A3	2.8e-09
NUP50	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Human	Intestine	A3	4.2e-08
NUP50	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
NUP50	GOBP_Protein_Localization_To_Nucleus	Human	Intestine	A3	7.7e-09
NUP50	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
NUP50	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Intestine	A3	1.2e-13
NUP50	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Intestine	A3	1.8e-12
NUP50	GOBP_Protein_Sumoylation	Human	Intestine	A3	1.2e-13
NUP50	GOBP_Purine_Containing_Compound_Metabolic_Process	Human	Intestine	A3	7.9e-07
NUP50	GOBP_Regulation_Of_Catabolic_Process	Human	Intestine	A3	3.5e-16
NUP50	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Intestine	A3	7.7e-17
NUP50	GOBP_Regulation_Of_Generation_Of_Precursor_Metabolites_And_Energy	Human	Intestine	A3	2.9e-14
NUP50	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Intestine	A3	1.5e-11
NUP50	GOBP_Regulation_Of_Response_To_Stress	Human	Intestine	A3	1.1e-10
NUP50	GOBP_Response_To_Abiotic_Stimulus	Human	Intestine	A3	5.3e-18
NUP50	GOBP_Response_To_Heat	Human	Intestine	A3	7.0e-22
NUP50	GOBP_Response_To_Temperature_Stimulus	Human	Intestine	A3	4.2e-20
NUP50	GOBP_Rna_Export_From_Nucleus	Human	Intestine	A3	3.3e-10
NUP50	GOBP_Rna_Localization	Human	Intestine	A3	1.4e-08
NUP50	GOBP_Viral_Life_Cycle	Human	Intestine	A3	1.1e-12
NUP50	GOBP_Carbohydrate_Catabolic_Process	Human	Intestine	A8	2.0e-14
NUP50	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Intestine	A8	7.3e-16
NUP50	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Human	Intestine	A8	5.4e-20
NUP50	GOBP_Nucleotide_Phosphorylation	Human	Intestine	A8	1.5e-18
NUP50	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
NUP50	GOBP_Pyruvate_Metabolic_Process	Human	Intestine	A8	1.4e-20
NUP50	GOBP_Regulation_Of_Atp_Metabolic_Process	Human	Intestine	A8	3.5e-13
NUP50	GOBP_Regulation_Of_Carbohydrate_Catabolic_Process	Human	Intestine	A8	8.4e-21
NUP50	GOBP_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Intestine	A8	1.8e-17
NUP50	GOBP_Regulation_Of_Cellular_Response_To_Heat	Human	Intestine	A8	3.0e-08
NUP50	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Intestine	A8	4.6e-12
NUP50	GOBP_Regulation_Of_Nucleotide_Metabolic_Process	Human	Intestine	A8	1.7e-16
NUP50	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Intestine	A8	1.7e-14
NUP50	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
NUP50	GOBP_Viral_Gene_Expression	Human	Intestine	A8	1.8e-23
NUP50	GOBP_Protein_Sumoylation	Human	Pancreas	PDAC-B-st1	2.0e-05
NUP50	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Pancreas	PDAC-B-st1	1.7e-05
NUP50	GOBP_Rna_Export_From_Nucleus	Human	Pancreas	PDAC-B-st1	6.7e-05
NUP50	GOBP_Mrna_Export_From_Nucleus	Human	Pancreas	PDAC-A-st2	3.9e-08
NUP50	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Uterus	rep_1	4.7e-07
NUP50	GOBP_Cellular_Response_To_Heat	Human	Uterus	rep_25	6.3e-09
NUP50	GOBP_Ncrna_Export_From_Nucleus	Human	Uterus	rep_25	6.1e-13
NUP50	GOBP_Nuclear_Export	Human	Uterus	rep_25	7.4e-11
NUP50	GOBP_Nuclear_Transport	Human	Uterus	rep_25	2.3e-13
NUP50	GOBP_Regulation_Of_Cellular_Response_To_Heat	Human	Uterus	rep_25	1.4e-10
NUP50	GOBP_Response_To_Temperature_Stimulus	Human	Uterus	rep_25	8.0e-06
NUP50	GOBP_Trna_Transport	Human	Uterus	rep_25	8.2e-09
NUP50	GOBP_Atp_Metabolic_Process	Human	Uterus	rep_26	3.2e-08
NUP50	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
NUP50	GOBP_Establishment_Of_Rna_Localization	Human	Uterus	rep_26	8.7e-07
NUP50	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Uterus	rep_26	1.8e-06
NUP50	GOBP_Mrna_Export_From_Nucleus	Human	Uterus	rep_26	3.9e-08
NUP50	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	2.4e-06
NUP50	GOBP_Nucleotide_Phosphorylation	Human	Uterus	rep_26	7.8e-08
NUP50	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
NUP50	GOBP_Peptidyl_Lysine_Modification	Human	Uterus	rep_26	2.3e-09
NUP50	GOBP_Protein_Import	Human	Uterus	rep_26	5.4e-13
NUP50	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Uterus	rep_26	2.1e-08
NUP50	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Uterus	rep_26	5.7e-08
NUP50	GOBP_Protein_Sumoylation	Human	Uterus	rep_26	1.1e-15
NUP50	GOBP_Purine_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.0e-06
NUP50	GOBP_Pyruvate_Metabolic_Process	Human	Uterus	rep_26	1.3e-06
NUP50	GOBP_Regulation_Of_Atp_Metabolic_Process	Human	Uterus	rep_26	1.5e-09
NUP50	GOBP_Regulation_Of_Carbohydrate_Catabolic_Process	Human	Uterus	rep_26	1.4e-07
NUP50	GOBP_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Uterus	rep_26	7.1e-09
NUP50	GOBP_Regulation_Of_Nucleotide_Metabolic_Process	Human	Uterus	rep_26	5.4e-12
NUP50	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	2.0e-14
NUP50	GOBP_Response_To_Heat	Human	Uterus	rep_26	3.4e-07
NUP50	GOBP_Rna_Export_From_Nucleus	Human	Uterus	rep_26	3.8e-10
NUP50	GOBP_Rna_Localization	Human	Uterus	rep_26	1.2e-09
NUP50	GOBP_Viral_Life_Cycle	Human	Uterus	rep_26	2.1e-06
NUP50	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Uterus	rep_29	2.8e-06
NUP50	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
NUP50	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
NUP50	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
NUP50	GOBP_Regulation_Of_Atp_Metabolic_Process	Human	Breast	rep_1	1.2e-73
NUP50	GOBP_Regulation_Of_Cellular_Response_To_Heat	Human	Breast	rep_1	1.9e-16
NUP50	GOBP_Regulation_Of_Nucleotide_Metabolic_Process	Human	Breast	rep_1	7.6e-116
NUP50	GOBP_Regulation_Of_Response_To_Stress	Human	Breast	rep_1	3.4e-19
NUP50	GOBP_Regulation_Of_Small_Molecule_Metabolic_Process	Human	Breast	rep_1	2.1e-94
NUP50	GOBP_Response_To_Abiotic_Stimulus	Human	Breast	rep_1	2.6e-19
NUP50	GOBP_Response_To_Temperature_Stimulus	Human	Breast	rep_1	1.2e-34
NUP50	GOBP_Viral_Life_Cycle	Human	Breast	rep_1	1.2e-08
NUP50	GOBP_Carbohydrate_Metabolic_Process	Human	Breast	rep_5	3.5e-10
NUP50	GOBP_Negative_Regulation_Of_Gene_Expression	Human	Breast	rep_5	5.3e-06
NUP50	GOBP_Protein_Localization_To_Nucleus	Human	Breast	rep_5	1.3e-04
NUP50	GOBP_Regulation_Of_Carbohydrate_Catabolic_Process	Human	Breast	rep_5	1.6e-05
NUP50	GOBP_Regulation_Of_Cellular_Response_To_Stress	Human	Breast	rep_5	8.1e-10
NUP50	GOBP_Regulation_Of_Gene_Silencing_By_Rna	Human	Breast	rep_5	4.0e-10
NUP50	GOBP_Regulation_Of_Generation_Of_Precursor_Metabolites_And_Energy	Human	Breast	rep_5	3.6e-04
NUP50	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Human	Breast	rep_5	2.5e-06
NUP50	GOBP_Viral_Gene_Expression	Human	Breast	rep_5	4.2e-10
NUP50	GOBP_Atp_Metabolic_Process	Human	Breast	rep_6	1.3e-06
NUP50	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
NUP50	GOBP_Cellular_Response_To_Heat	Human	Breast	rep_6	1.3e-04
NUP50	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Breast	rep_6	8.5e-11
NUP50	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Breast	rep_6	7.1e-09
NUP50	GOBP_Import_Into_Nucleus	Human	Breast	rep_6	4.5e-08
NUP50	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
NUP50	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
NUP50	GOBP_Monocarboxylic_Acid_Metabolic_Process	Human	Breast	rep_6	6.1e-07
NUP50	GOBP_Mrna_Export_From_Nucleus	Human	Breast	rep_6	1.1e-04
NUP50	GOBP_Mrna_Transport	Human	Breast	rep_6	1.9e-10
NUP50	GOBP_Ncrna_Export_From_Nucleus	Human	Breast	rep_6	1.1e-04
NUP50	GOBP_Nuclear_Export	Human	Breast	rep_6	1.4e-05
NUP50	GOBP_Nuclear_Transport	Human	Breast	rep_6	3.1e-08
NUP50	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	1.7e-10
NUP50	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Human	Breast	rep_6	4.5e-05
NUP50	GOBP_Nucleotide_Phosphorylation	Human	Breast	rep_6	2.0e-05
NUP50	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
NUP50	GOBP_Organophosphate_Metabolic_Process	Human	Breast	rep_6	1.0e-12
NUP50	GOBP_Peptidyl_Amino_Acid_Modification	Human	Breast	rep_6	3.8e-05
NUP50	GOBP_Peptidyl_Lysine_Modification	Human	Breast	rep_6	4.5e-08
NUP50	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
NUP50	GOBP_Protein_Import	Human	Breast	rep_6	3.9e-08
NUP50	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
NUP50	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Human	Breast	rep_6	3.6e-10
NUP50	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Human	Breast	rep_6	2.7e-09
NUP50	GOBP_Protein_Sumoylation	Human	Breast	rep_6	3.6e-08
NUP50	GOBP_Purine_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	2.5e-09
NUP50	GOBP_Pyruvate_Metabolic_Process	Human	Breast	rep_6	1.0e-04
NUP50	GOBP_Regulation_Of_Carbohydrate_Metabolic_Process	Human	Breast	rep_6	4.9e-04
NUP50	GOBP_Regulation_Of_Catabolic_Process	Human	Breast	rep_6	3.3e-04
NUP50	GOBP_Rna_Export_From_Nucleus	Human	Breast	rep_6	9.6e-09
NUP50	GOBP_Rna_Localization	Human	Breast	rep_6	7.7e-05
NUP50	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
NUP50	GOBP_Import_Into_Nucleus	Human	Skin	P5_rep1	3.8e-09
NUP50	GOBP_Nuclear_Transport	Human	Skin	P5_rep1	5.0e-19
NUP50	GOBP_Regulation_Of_Generation_Of_Precursor_Metabolites_And_Energy	Human	Skin	P5_rep3	1.3e-09
NUP50	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
NUP50	GOBP_Regulation_Of_Cellular_Response_To_Heat	Human	Skin	P10_rep2	7.2e-13
NUP50	GOBP_Trna_Transport	Human	Skin	P10_rep2	3.5e-12
NUP50	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
NUP50	GOBP_Viral_Life_Cycle	Human	Lung	rep_1	2.0e-16

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NUP50 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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NUP50 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for NUP50 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for NUP50

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for NUP50

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source