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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: OGA (spascer ID:10724)

Gene summary for OGA

Gene summary

Gene information
	Species	Human
	Gene symbol	OGA
	Gene ID	10724
	Gene name	O-GlcNAcase
	Synonyms	MEA5\|MGEA5\|NCOAT
	Cytomap	10q24.32
	Type of gene	protein-coding
	Description	protein O-GlcNAcaseN-acetyl-beta-D-glucosaminidaseN-acetyl-beta-glucosaminidasebeta-N-acetylglucosaminidasebeta-N-acetylhexosaminidasebeta-hexosaminidasebifunctional protein NCOAThyaluronidase in meningiomameningioma expressed antigen 5 (hyaluroni
	Modification date	20220513
	UniProtAcc	O60502

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
OGA	GO:0009100	glycoprotein metabolic process	21873635	Process
OGA	GO:0016231	beta-N-acetylglucosaminidase activity	21873635	Function

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Spatial pattern events for OGA

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
OGA	Human	Intestine	rep_colon1	34417225	1.95e-15
OGA	Human	Intestine	rep_colon2	34417225	8.12e-16
OGA	Human	Intestine	rep_colon4	34417225	1.14e-15
OGA	Human	Liver	rep_liver1	34417225	1.89e-15
OGA	Human	Liver	rep_liver2	34417225	6.98e-16
OGA	Human	Liver	rep_liver4	34417225	1.85e-07
OGA	Human	Intestine	A1	33406409	3.53e-07
OGA	Human	Intestine	A2	33406409	2.52e-07
OGA	Human	Intestine	A4	33406409	2.57e-09
OGA	Human	Uterus	rep_2	34857954	2.63e-06
OGA	Human	Uterus	rep_4	34857954	3.39e-15
OGA	Human	Breast	1142243F	34493872	1.79e-06
OGA	Human	Breast	1160920F	34493872	3.47e-14
OGA	Human	Breast	CID4290	34493872	8.08e-15
OGA	Human	Breast	CID44971	34493872	1.37e-11

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Intestine_A1_H&E
Intestine_A2_H&E
Intestine_A4_H&E
Uterus_rep_2_H&E
Uterus_rep_4_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has OGA envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
OGA	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Bladder	rep_4	3.0e-06
OGA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
OGA	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Intestine	A3	1.8e-09
OGA	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
OGA	GOBP_Macromolecule_Catabolic_Process	Human	Intestine	A3	2.2e-16
OGA	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Intestine	A3	4.5e-13
OGA	GOBP_Protein_Catabolic_Process	Human	Intestine	A3	2.9e-14
OGA	GOBP_Amino_Sugar_Metabolic_Process	Human	Intestine	A8	5.1e-12
OGA	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Intestine	A8	3.2e-10
OGA	GOBP_Glucosamine_Containing_Compound_Metabolic_Process	Human	Intestine	A8	3.8e-12
OGA	GOBP_Glycoprotein_Biosynthetic_Process	Human	Intestine	A8	1.4e-09
OGA	GOBP_Glycoprotein_Catabolic_Process	Human	Intestine	A8	1.3e-12
OGA	GOBP_Glycoprotein_Metabolic_Process	Human	Intestine	A8	5.3e-08
OGA	GOBP_Glycosylation	Human	Intestine	A8	1.2e-17
OGA	GOBP_N_Acetylglucosamine_Metabolic_Process	Human	Intestine	A8	3.3e-14
OGA	GOBP_Protein_O_Linked_Glycosylation	Human	Intestine	A8	1.2e-13
OGA	GOBP_Protein_O_Linked_Glycosylation	Human	Pancreas	PDAC-B-st1	5.7e-05
OGA	GOBP_Amino_Sugar_Metabolic_Process	Human	Uterus	rep_1	2.9e-06
OGA	GOBP_Glucosamine_Containing_Compound_Metabolic_Process	Human	Uterus	rep_1	8.1e-06
OGA	GOBP_Protein_O_Linked_Glycosylation	Human	Uterus	rep_1	5.9e-06
OGA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
OGA	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Uterus	rep_26	3.5e-11
OGA	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Uterus	rep_26	5.1e-11
OGA	GOBP_Glycoprotein_Catabolic_Process	Human	Uterus	rep_26	5.6e-10
OGA	GOBP_Macromolecule_Catabolic_Process	Human	Uterus	rep_26	5.0e-08
OGA	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Uterus	rep_26	1.0e-08
OGA	GOBP_Protein_Catabolic_Process	Human	Uterus	rep_26	3.6e-10
OGA	GOBP_Amino_Sugar_Metabolic_Process	Human	Breast	rep_1	1.6e-44
OGA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
OGA	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Breast	rep_1	2.1e-06
OGA	GOBP_Glucosamine_Containing_Compound_Metabolic_Process	Human	Breast	rep_1	8.1e-46
OGA	GOBP_Glycoprotein_Catabolic_Process	Human	Breast	rep_1	1.2e-90
OGA	GOBP_N_Acetylglucosamine_Metabolic_Process	Human	Breast	rep_1	1.3e-36
OGA	GOBP_Carbohydrate_Derivative_Catabolic_Process	Human	Breast	rep_5	1.1e-09
OGA	GOBP_Glycoprotein_Metabolic_Process	Human	Breast	rep_5	1.5e-14
OGA	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
OGA	GOBP_Glycoprotein_Biosynthetic_Process	Human	Breast	rep_6	4.8e-07
OGA	GOBP_Glycosylation	Human	Breast	rep_6	5.3e-04
OGA	GOBP_Macromolecule_Catabolic_Process	Human	Breast	rep_6	1.3e-05
OGA	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
OGA	GOBP_Organonitrogen_Compound_Catabolic_Process	Human	Breast	rep_6	9.5e-06
OGA	GOBP_Protein_Catabolic_Process	Human	Breast	rep_6	5.3e-06
OGA	GOBP_Protein_Deglycosylation	Human	Breast	rep_6	6.2e-07
OGA	GOBP_Protein_O_Linked_Glycosylation	Human	Breast	rep_6	2.5e-05
OGA	GOBP_Amino_Sugar_Metabolic_Process	Human	Skin	P2_rep2	4.1e-08
OGA	GOBP_Glucosamine_Containing_Compound_Metabolic_Process	Human	Skin	P2_rep2	1.6e-21
OGA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
OGA	GOBP_Glycoprotein_Catabolic_Process	Human	Skin	P9_rep2	2.2e-08
OGA	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
OGA	GOBP_Glycoprotein_Catabolic_Process	Human	Lung	rep_1	2.1e-11

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OGA function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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OGA function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for OGA envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for OGA

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
OGA	O60502	DB00428	Streptozocin	Protein O-GlcNAcase	SmallMoleculeDrug	approved\|investigational

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Related Diseases for OGA

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source