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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 9909

FusionGeneSummary for DHX30_MAP4

check button Fusion gene summary
Fusion gene informationFusion gene name: DHX30_MAP4
Fusion gene ID: 9909
HgeneTgene
Gene symbol

DHX30

MAP4

Gene ID

22907

4134

Gene nameDExH-box helicase 30microtubule associated protein 4
SynonymsDDX30|NEDMIAL|RETCOR-
Cytomap

3p21.31

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionputative ATP-dependent RNA helicase DHX30DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 30DEAH (Asp-Glu-Ala-His) box helicase 30DEAH (Asp-Glu-Ala-His) box polypeptide 30DEAH box protein 30DEAH-box helicase 30retina co-repressormicrotubule-associated protein 4MAP-4
Modification date2018052320180523
UniProtAcc

Q7L2E3

P27816

Ensembl transtripts involved in fusion geneENST00000446256, ENST00000445061, 
ENST00000476446, ENST00000348968, 
ENST00000457607, 		ENST00000383737, 
ENST00000395734, ENST00000426837, 
ENST00000360240, ENST00000439356, 
ENST00000264724, ENST00000420772, 
ENST00000441748, ENST00000462206, 
ENST00000434267, 
Fusion gene scores* DoF score7 X 6 X 6=2527 X 10 X 3=210
# samples 810
** MAII scorelog2(8/252*10)=-1.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/210*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DHX30 [Title/Abstract] AND MAP4 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLGGTCGA-HT-7695-01ADHX30chr3

47870624

+MAP4chr3

47913590

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000446256ENST00000383737DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000446256ENST00000395734DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000446256ENST00000426837DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000446256ENST00000360240DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000446256ENST00000439356DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000446256ENST00000264724DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000446256ENST00000420772DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000446256ENST00000441748DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000446256ENST00000462206DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000446256ENST00000434267DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000445061ENST00000383737DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000445061ENST00000395734DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000445061ENST00000426837DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000445061ENST00000360240DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000445061ENST00000439356DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000445061ENST00000264724DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000445061ENST00000420772DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000445061ENST00000441748DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000445061ENST00000462206DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000445061ENST00000434267DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-3CDSENST00000476446ENST00000383737DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-3CDSENST00000476446ENST00000395734DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-3CDSENST00000476446ENST00000426837DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-3CDSENST00000476446ENST00000360240DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-intronENST00000476446ENST00000439356DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-intronENST00000476446ENST00000264724DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-intronENST00000476446ENST00000420772DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-5UTRENST00000476446ENST00000441748DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-5UTRENST00000476446ENST00000462206DHX30chr3

47870624

+MAP4chr3

47913590

-
intron-intronENST00000476446ENST00000434267DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000348968ENST00000383737DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000348968ENST00000395734DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000348968ENST00000426837DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000348968ENST00000360240DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000348968ENST00000439356DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000348968ENST00000264724DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000348968ENST00000420772DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000348968ENST00000441748DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000348968ENST00000462206DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000348968ENST00000434267DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000457607ENST00000383737DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000457607ENST00000395734DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000457607ENST00000426837DHX30chr3

47870624

+MAP4chr3

47913590

-
In-frameENST00000457607ENST00000360240DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000457607ENST00000439356DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000457607ENST00000264724DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000457607ENST00000420772DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000457607ENST00000441748DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-5UTRENST00000457607ENST00000462206DHX30chr3

47870624

+MAP4chr3

47913590

-
5CDS-intronENST00000457607ENST00000434267DHX30chr3

47870624

+MAP4chr3

47913590

-

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FusionProtFeatures for DHX30_MAP4


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DHX30

Q7L2E3

MAP4

P27816

Plays an important role in the assembly of themitochondrial large ribosomal subunit (PubMed:25683715). Requiredfor optimal function of the zinc-finger antiviral protein ZC3HAV1(By similarity). Associates with mitochondrial DNA(PubMed:18063578). {ECO:0000250|UniProtKB:Q5BJS0,ECO:0000269|PubMed:18063578, ECO:0000269|PubMed:25683715}. Non-neuronal microtubule-associated protein. Promotesmicrotubule assembly. {ECO:0000269|PubMed:10791892}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDHX30chr3:47870624chr3:47913590ENST00000445061+62253_1211221195DomainNote=DRBM
HgeneDHX30chr3:47870624chr3:47913590ENST00000457607+31953_1211501223DomainNote=DRBM
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04248_545-33100RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04248_545-24100RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-9191023_10537741153RepeatNote=Tau/MAP 3
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-9191054_10857741153RepeatNote=Tau/MAP 4
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919923_9537741153RepeatNote=Tau/MAP 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919992_10227741153RepeatNote=Tau/MAP 2
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-9181023_10537741136RepeatNote=Tau/MAP 3
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-9181054_10857741136RepeatNote=Tau/MAP 4
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918923_9537741136RepeatNote=Tau/MAP 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918992_10227741136RepeatNote=Tau/MAP 2
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-041023_1053-33100RepeatNote=Tau/MAP 3
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-041054_1085-33100RepeatNote=Tau/MAP 4
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04248_261-33100RepeatNote=1
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04262_275-33100RepeatNote=2
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04276_289-33100RepeatNote=3
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04290_303-33100RepeatNote=4
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04304_317-33100RepeatNote=5
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04318_331-33100RepeatNote=6
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04332_345-33100RepeatNote=7
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04346_351-33100RepeatNote=8%3B truncated
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04352_377-33100RepeatNote=26 residues 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04378_403-33100RepeatNote=26 residues 2
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04408_421-33100RepeatNote=9
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04422_433-33100RepeatNote=10
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04434_447-33100RepeatNote=11
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04448_461-33100RepeatNote=12
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04462_475-33100RepeatNote=13
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04476_489-33100RepeatNote=14
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04490_503-33100RepeatNote=15
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04504_517-33100RepeatNote=16
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04532_545-33100RepeatNote=17
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04923_953-33100RepeatNote=Tau/MAP 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000434267-04992_1022-33100RepeatNote=Tau/MAP 2
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-041023_1053-24100RepeatNote=Tau/MAP 3
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-041054_1085-24100RepeatNote=Tau/MAP 4
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04248_261-24100RepeatNote=1
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04262_275-24100RepeatNote=2
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04276_289-24100RepeatNote=3
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04290_303-24100RepeatNote=4
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04304_317-24100RepeatNote=5
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04318_331-24100RepeatNote=6
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04332_345-24100RepeatNote=7
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04346_351-24100RepeatNote=8%3B truncated
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04352_377-24100RepeatNote=26 residues 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04378_403-24100RepeatNote=26 residues 2
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04408_421-24100RepeatNote=9
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04422_433-24100RepeatNote=10
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04434_447-24100RepeatNote=11
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04448_461-24100RepeatNote=12
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04462_475-24100RepeatNote=13
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04476_489-24100RepeatNote=14
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04490_503-24100RepeatNote=15
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04504_517-24100RepeatNote=16
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04532_545-24100RepeatNote=17
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04923_953-24100RepeatNote=Tau/MAP 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000439356-04992_1022-24100RepeatNote=Tau/MAP 2

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDHX30chr3:47870624chr3:47913590ENST00000445061+622188_1991221195Compositional biasNote=Poly-Glu
HgeneDHX30chr3:47870624chr3:47913590ENST00000446256+723188_199831156Compositional biasNote=Poly-Glu
HgeneDHX30chr3:47870624chr3:47913590ENST00000457607+319188_1991501223Compositional biasNote=Poly-Glu
HgeneDHX30chr3:47870624chr3:47913590ENST00000445061+622444_6121221195DomainHelicase ATP-binding
HgeneDHX30chr3:47870624chr3:47913590ENST00000445061+622654_8271221195DomainHelicase C-terminal
HgeneDHX30chr3:47870624chr3:47913590ENST00000446256+723444_612831156DomainHelicase ATP-binding
HgeneDHX30chr3:47870624chr3:47913590ENST00000446256+72353_121831156DomainNote=DRBM
HgeneDHX30chr3:47870624chr3:47913590ENST00000446256+723654_827831156DomainHelicase C-terminal
HgeneDHX30chr3:47870624chr3:47913590ENST00000457607+319444_6121501223DomainHelicase ATP-binding
HgeneDHX30chr3:47870624chr3:47913590ENST00000457607+319654_8271501223DomainHelicase C-terminal
HgeneDHX30chr3:47870624chr3:47913590ENST00000445061+622559_5621221195MotifNote=DEAH box
HgeneDHX30chr3:47870624chr3:47913590ENST00000446256+723559_562831156MotifNote=DEAH box
HgeneDHX30chr3:47870624chr3:47913590ENST00000457607+319559_5621501223MotifNote=DEAH box
HgeneDHX30chr3:47870624chr3:47913590ENST00000445061+622457_4641221195Nucleotide bindingATP
HgeneDHX30chr3:47870624chr3:47913590ENST00000446256+723457_464831156Nucleotide bindingATP
HgeneDHX30chr3:47870624chr3:47913590ENST00000457607+319457_4641501223Nucleotide bindingATP
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919248_5457741153RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918248_5457741136RegionNote=17 X 14 AA tandem repeats
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919248_2617741153RepeatNote=1
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919262_2757741153RepeatNote=2
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919276_2897741153RepeatNote=3
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919290_3037741153RepeatNote=4
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919304_3177741153RepeatNote=5
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919318_3317741153RepeatNote=6
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919332_3457741153RepeatNote=7
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919346_3517741153RepeatNote=8%3B truncated
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919352_3777741153RepeatNote=26 residues 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919378_4037741153RepeatNote=26 residues 2
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919408_4217741153RepeatNote=9
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919422_4337741153RepeatNote=10
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919434_4477741153RepeatNote=11
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919448_4617741153RepeatNote=12
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919462_4757741153RepeatNote=13
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919476_4897741153RepeatNote=14
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919490_5037741153RepeatNote=15
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919504_5177741153RepeatNote=16
TgeneMAP4chr3:47870624chr3:47913590ENST00000360240-919532_5457741153RepeatNote=17
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918248_2617741136RepeatNote=1
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918262_2757741136RepeatNote=2
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918276_2897741136RepeatNote=3
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918290_3037741136RepeatNote=4
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918304_3177741136RepeatNote=5
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918318_3317741136RepeatNote=6
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918332_3457741136RepeatNote=7
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918346_3517741136RepeatNote=8%3B truncated
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918352_3777741136RepeatNote=26 residues 1
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918378_4037741136RepeatNote=26 residues 2
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918408_4217741136RepeatNote=9
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918422_4337741136RepeatNote=10
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918434_4477741136RepeatNote=11
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918448_4617741136RepeatNote=12
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918462_4757741136RepeatNote=13
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918476_4897741136RepeatNote=14
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918490_5037741136RepeatNote=15
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918504_5177741136RepeatNote=16
TgeneMAP4chr3:47870624chr3:47913590ENST00000395734-918532_5457741136RepeatNote=17


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FusionGeneSequence for DHX30_MAP4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for DHX30_MAP4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
DHX30H2AFX, ICT1, DHX58, OAS3, EIF2AK2, HDGF, SIRT7, HNRNPA1, CUL3, CUL4B, CUL5, CUL1, COPS5, CAND1, GRK5, ILF3, GNAI2, RAB31, NDUFA2, ESR1, FN1, SKIL, HNRNPD, TARDBP, NEDD4, WWOX, GRSF1, IVNS1ABP, STAU1, ENO1, MOV10, NXF1, OBSL1, CCDC8, EZH2, SUZ12, RNF2, HIST1H1A, PRR11, ILF2, NTRK1, IFI16, TCTN2, HNRNPU, RPL10, NOP56, IBTK, LDHD, KMT2E, NF2, FAM136A, CISD3, ZNF746, MCMBP, WDR46, RRS1, GLTSCR2, RPL18A, ZNF2, FGF8, RRP8, ZC3HAV1, ZNF324B, CDX1, RPL30, CPNE4, GPATCH4, RPL37A, PDGFB, ZNF71, PPAN, HIST1H1E, DGCR8, RPL18, RBM34, CNBP, FGF3, SART3, LTF, ZFC3H1, GSPT2, RPS14, STUB1, NKRF, NCL, CYLD, INO80B, COX15, PDHA1, G3BP1, MTF1MAP4MARK4, ENO2, CDK1, FYCO1, NR1I3, RXRB, RXRG, GSK3B, HDGF, SIRT7, SH3KBP1, ISG15, TERF1, POT1, CUL4A, USP21, GRK5, EPS15, AP2M1, RPS20, UBC, TRAF3IP1, FN1, IL7R, ERBB2IP, SNTA1, BAG3, LDLR, TARDBP, HNRNPF, COG7, CSTF2, EIF2S1, HNRNPR, IARS, MTA2, POLR2A, POLR2C, PPP4R1, WDHD1, LSM8, PDCD6, RPA3, RPA2, RPA1, LGR4, CCDC8, ABCE1, FLNB, LSM3, HSPA5, LASP1, SERBP1, SLK, NTRK1, SRPK2, KIF11, CRY2, OTUB1, CDH1, EGFR, G3BP1, BRCA1, YAP1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for DHX30_MAP4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneMAP4P27816DB01248DocetaxelMicrotubule-associated protein 4small moleculeapproved|investigational
TgeneMAP4P27816DB11638ArtenimolMicrotubule-associated protein 4small moleculeapproved|investigational
TgeneMAP4P27816DB01229PaclitaxelMicrotubule-associated protein 4small moleculeapproved|vet_approved

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RelatedDiseases for DHX30_MAP4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMAP4C0043094Weight Gain1CTD_human