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Fusion gene ID: 9681 |
FusionGeneSummary for DECR1_STAU2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DECR1_STAU2 | Fusion gene ID: 9681 | Hgene | Tgene | Gene symbol | DECR1 | STAU2 | Gene ID | 1666 | 27067 |
| Gene name | 2,4-dienoyl-CoA reductase 1 | staufen double-stranded RNA binding protein 2 | |
| Synonyms | DECR|NADPH|SDR18C1 | 39K2|39K3 | |
| Cytomap | 8q21.3 | 8q21.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 2,4-dienoyl-CoA reductase, mitochondrial2,4-dienoyl-CoA reductase 1, mitochondrial4-enoyl-CoA reductaseshort chain dehydrogenase/reductase family 18C member 1 | double-stranded RNA-binding protein Staufen homolog 2staufen homolog 2staufen, RNA binding protein, homolog 2 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q16698 | Q9NUL3 | |
| Ensembl transtripts involved in fusion gene | ENST00000220764, ENST00000519007, ENST00000522161, | ENST00000522695, ENST00000524300, ENST00000523558, ENST00000521210, ENST00000355780, ENST00000519961, ENST00000521727, ENST00000521451, ENST00000522509, ENST00000517542, ENST00000524104, ENST00000522962, ENST00000521419, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 10 X 9 X 5=450 |
| # samples | 2 | 12 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(12/450*10)=-1.90689059560852 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DECR1 [Title/Abstract] AND STAU2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DECR1 | GO:0006635 | fatty acid beta-oxidation | 15531764 |
| Hgene | DECR1 | GO:0051289 | protein homotetramerization | 15531764 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | ESCA | TCGA-2H-A9GG-01A | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000220764 | ENST00000522695 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| Frame-shift | ENST00000220764 | ENST00000524300 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| Frame-shift | ENST00000220764 | ENST00000523558 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| Frame-shift | ENST00000220764 | ENST00000521210 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| In-frame | ENST00000220764 | ENST00000355780 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| In-frame | ENST00000220764 | ENST00000519961 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| Frame-shift | ENST00000220764 | ENST00000521727 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| Frame-shift | ENST00000220764 | ENST00000521451 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| Frame-shift | ENST00000220764 | ENST00000522509 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| In-frame | ENST00000220764 | ENST00000517542 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5CDS-intron | ENST00000220764 | ENST00000524104 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5CDS-intron | ENST00000220764 | ENST00000522962 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5CDS-intron | ENST00000220764 | ENST00000521419 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000522695 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000524300 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000523558 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000521210 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000355780 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000519961 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000521727 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000521451 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000522509 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-3CDS | ENST00000519007 | ENST00000517542 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-intron | ENST00000519007 | ENST00000524104 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-intron | ENST00000519007 | ENST00000522962 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 3UTR-intron | ENST00000519007 | ENST00000521419 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000522695 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000524300 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000523558 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000521210 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000355780 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000519961 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000521727 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000521451 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000522509 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-3CDS | ENST00000522161 | ENST00000517542 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-intron | ENST00000522161 | ENST00000524104 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-intron | ENST00000522161 | ENST00000522962 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
| 5UTR-intron | ENST00000522161 | ENST00000521419 | DECR1 | chr8 | 91013789 | + | STAU2 | chr8 | 74464554 | - |
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FusionProtFeatures for DECR1_STAU2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DECR1 | STAU2 |
| Auxiliary enzyme of beta-oxidation. It participates inthe metabolism of unsaturated fatty enoyl-CoA esters having doublebonds in both even- and odd-numbered positions. Catalyzes theNADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for DECR1_STAU2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000355780_chr8_74464554_-_127aa MKLPARVFFTLGSRLPCGLAPRRLQKEFFICLLMFIKRWKPAATKXSLALLXAICHPKIXTNLQALSSVYLPHRIVQLQLPGNSLXMEHL >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000519961_chr8_74464554_-_127aa MKLPARVFFTLGSRLPCGLAPRRLQKEFFICLLMFIKRWKPAATKXSLALLXAICHPKIXTNLQALSSVYLPHRIVQLQLPGNSLXMEHL >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000517542_chr8_74464554_-_127aa MKLPARVFFTLGSRLPCGLAPRRLQKEFFICLLMFIKRWKPAATKXSLALLXAICHPKIXTNLQALSSVYLPHRIVQLQLPGNSLXMEHL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000355780_chr8_74464554_-_383nt ATGAAGCTACCGGCCAGGGTTTTCTTTACTCTGGGGTCCCGGCTGCCCTGTGGCCTCGCTCCTCGGAGGCTCCAAAAGGAATTCTTCATT TGTCTCCTGATGTTTATCAAGAGATGGAAGCCAGCCGCCACAAAGTAATCTCTGGCACTACTCTAGGCTATTTGTCACCCAAAGATATGA ACCAACCTTCAAGCTCTTTCTTCAGTATATCTCCCACATCGAATAGTTCAGCTACAATTGCCAGGGAACTCCTTATGAATGGAACATCTT CTACAGCTGAAGCCATAGGTTTAAAAGGAAGTTCTCCTACTCCCCCTTGTTCTCCAGTACAACCTTCAAAACAACTGGAATATTTAGCAA >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000519961_chr8_74464554_-_383nt ATGAAGCTACCGGCCAGGGTTTTCTTTACTCTGGGGTCCCGGCTGCCCTGTGGCCTCGCTCCTCGGAGGCTCCAAAAGGAATTCTTCATT TGTCTCCTGATGTTTATCAAGAGATGGAAGCCAGCCGCCACAAAGTAATCTCTGGCACTACTCTAGGCTATTTGTCACCCAAAGATATGA ACCAACCTTCAAGCTCTTTCTTCAGTATATCTCCCACATCGAATAGTTCAGCTACAATTGCCAGGGAACTCCTTATGAATGGAACATCTT CTACAGCTGAAGCCATAGGTTTAAAAGGAAGTTCTCCTACTCCCCCTTGTTCTCCAGTACAACCTTCAAAACAACTGGAATATTTAGCAA >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000517542_chr8_74464554_-_383nt ATGAAGCTACCGGCCAGGGTTTTCTTTACTCTGGGGTCCCGGCTGCCCTGTGGCCTCGCTCCTCGGAGGCTCCAAAAGGAATTCTTCATT TGTCTCCTGATGTTTATCAAGAGATGGAAGCCAGCCGCCACAAAGTAATCTCTGGCACTACTCTAGGCTATTTGTCACCCAAAGATATGA ACCAACCTTCAAGCTCTTTCTTCAGTATATCTCCCACATCGAATAGTTCAGCTACAATTGCCAGGGAACTCCTTATGAATGGAACATCTT CTACAGCTGAAGCCATAGGTTTAAAAGGAAGTTCTCCTACTCCCCCTTGTTCTCCAGTACAACCTTCAAAACAACTGGAATATTTAGCAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000355780_chr8_74464554_-_2873nt TCCAGCCCCGAGAACTTTGTTCTTTTTGTCCCGCCCCCTGCGCCCAACCGCCTGCGCCGCCTTCCGGCCCGAGTTCTGGAGACTCAACAT GAAGCTACCGGCCAGGGTTTTCTTTACTCTGGGGTCCCGGCTGCCCTGTGGCCTCGCTCCTCGGAGGCTCCAAAAGGAATTCTTCATTTG TCTCCTGATGTTTATCAAGAGATGGAAGCCAGCCGCCACAAAGTAATCTCTGGCACTACTCTAGGCTATTTGTCACCCAAAGATATGAAC CAACCTTCAAGCTCTTTCTTCAGTATATCTCCCACATCGAATAGTTCAGCTACAATTGCCAGGGAACTCCTTATGAATGGAACATCTTCT ACAGCTGAAGCCATAGGTTTAAAAGGAAGTTCTCCTACTCCCCCTTGTTCTCCAGTACAACCTTCAAAACAACTGGAATATTTAGCAAGG ATTCAAGGCTTTCAGGTATGAATTAAAAGCAAAAACAAAAAACAAAACAATTCATTAGCCTCAGATTCTTCATCTGTATACATCACAAGG CTCATTCTTGCCTGCTAGTATGGCCTACATGCCACTTACGTTTTAAGTTATTTAGGAACACAAAGGACAGACAAAAAAGCCATATGCACA TGCCTCATTTTCTCTTATTTTTGATCTATCTAGTAATTCTTTTGCTGCCTGTCTCTTCTCCATTTTCCTTCTTCTTTTTTAAGCATTTTT CATATTCTTCACTGTCTTCTATTTGGTCTTGATTAGGTGCATCTATCTCTTCGCTCTGTCTTCCACAAACAAAAATTCTGCCTTCAGACA TTTGGTGTTAGTATTTCACACTCAGTTCTCCCTTTTTTTACATAAGGATTGAGTTTCTTTTTATGATGATTTTACCTTTATAGCAATTTT GAATTTTGCATTCTATTGCTAGTATTGATTCAGGTACACCATTAAGATACAACATTCTAGAAGTCTATTACCTTAGGAGTTAATTAAACA TGATATTTGAAGAATAATGAAATGCTTTATAGTTGTTTGAGGCATAACAATGTGTATTTGTTTTACTGGATCATGTTTTGAACTGACTAG GGAGGGTAGCACCTGCCTCAGATAGTACCAACAATTCTGTTTCACTGGGTAGTCTAAAACTAGCTTATAGTTTAACTTAACTTGTTGTGT ATGTGAATTTAGGGATGGAAACTTTTTTTCCCCTATTTATTCTTTGTTTCCTTCTGGGAAAAAACCCCACAAAAATCAGCACTCCTTTAT GGATACATTGGAGCTTTTGAAAGAATTGTAAACTCTAGGAAGGGGAAATATCTGTGTCTTGATTTCTTAGTTGCCTTGAAAATCATGTAC TGAACTGTAACCGCTAACTTGACTGGATGAACTAGTTTGCTTGTGTGTAGAGAGTGTATTGCTTCCTCAGATTTCACTGTTTTCATCTCC TTTTCCATCTTAGTCTTTATTCCTTAAGACCAAAAACTGTAATATCCTTTAGAAATGCTCTAGAAGATCTGTATTGTGTAGAATGATCAT GTATTTATAAATATTTTACAAGTTTAGATTATAAAATGAAAAAGAAGGTCATGTGTTTTGGGGGGTATTTTGCATGTTCGGATTTTTTTT TCACTTCACCGAACCCTTCTGATTCTTTCAAACTATTGCCAGGTAGTTGTTAGTGTTTCTAATTGGACTCTTAATATGAACTTCAAGAAG CTGTTACCAGTTATCGGCTCTGTCATCTGAAATTTTAACCACTTAATTTAAAGTTACAATTTTAGAATTTGTTTTTGTTGTTTTACCTTA AGAAACACAATAAATCACTGTTTAAAAAAGATCTCAATTTATATAAAGTACTGGAAAAAAGCTAAGTAATTTTTAGTTCTATCTATAATC TCCGTAGGATGAATTAGAAATAAATTGTGATGAAAAGAAATTAACTGCTTATTTATGAATCTAATCATTTAGAAATGTCTGAGAGTAACA CTGCATTCTTATAGAAACAAAGCACAAATTGCATTCAAGCTCTGAATTGATTTTTTGCTTGGAGCTGTTGTTACAGTAGCTGTAATTTTG CTACCAGAATGTCTTAATTTTTTAAATTTGTTTTTATTTCTAAGCTCTTGGCAATGACAATAATTATAATTTTAACATATCTTCACTGTA GTCAACATGTAGAGTCTGCTTCCCTCATTATTGCATTGCTAAGGCCTTTTTAAAAAGCTTATGCTTACATAATATACTCTTTTTTATGGA CACGTTATATGTTTCCAAATCTGTGTATTGTGATTTTTACATACTAATGAATATAAACAGGTGATTTTAAAATATTACTGTGCTTCTTTG GTTGAATGAGCTGGTATTGATGTAAAATACTCTGTCATTGATGGACCACTACCTGCAGCTAAGCAGTGAGCAGAATCTCCGGGAAATGAC TTAGTCTGGCCACATGCATAGCCCATCTTCATAATGTCGCAGCAGAAGGTTCTTTGTGGTTAAAAGTTTTAAAGCCTATTTCTTTATAGG TAACCCTCTCAGGTATATTTACCTGGTAGAAAAACATGTAGATTGTTTCTATTACTTAAATGTTTTAATTGGACTGTAGTTTAGAAATTA CAGGACCAGCTTGTTACAGATTATACACTATTCTGTTACTTTTATTTCTGAAACTTAAAAACAATAAATTCTTTTTCTGTGTTTCTAGGT TAGAACTTTTTTATTTTATTGCACACTGAACAGATACTGTTGCTTATTGAATATTGTGTAAACCCTTCTTTGGCTTTCCTTGCCCATTGC >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000519961_chr8_74464554_-_2785nt TCCAGCCCCGAGAACTTTGTTCTTTTTGTCCCGCCCCCTGCGCCCAACCGCCTGCGCCGCCTTCCGGCCCGAGTTCTGGAGACTCAACAT GAAGCTACCGGCCAGGGTTTTCTTTACTCTGGGGTCCCGGCTGCCCTGTGGCCTCGCTCCTCGGAGGCTCCAAAAGGAATTCTTCATTTG TCTCCTGATGTTTATCAAGAGATGGAAGCCAGCCGCCACAAAGTAATCTCTGGCACTACTCTAGGCTATTTGTCACCCAAAGATATGAAC CAACCTTCAAGCTCTTTCTTCAGTATATCTCCCACATCGAATAGTTCAGCTACAATTGCCAGGGAACTCCTTATGAATGGAACATCTTCT ACAGCTGAAGCCATAGGTTTAAAAGGAAGTTCTCCTACTCCCCCTTGTTCTCCAGTACAACCTTCAAAACAACTGGAATATTTAGCAAGG ATTCAAGGCTTTCAGGTATGAATTAAAAGCAAAAACAAAAAACAAAACAATTCATTAGCCTCAGATTCTTCATCTGTATACATCACAAGG CTCATTCTTGCCTGCTAGTATGGCCTACATGCCACTTACGTTTTAAGTTATTTAGGAACACAAAGGACAGACAAAAAAGCCATATGCACA TGCCTCATTTTCTCTTATTTTTGATCTATCTAGTAATTCTTTTGCTGCCTGTCTCTTCTCCATTTTCCTTCTTCTTTTTTAAGCATTTTT CATATTCTTCACTGTCTTCTATTTGGTCTTGATTAGGTGCATCTATCTCTTCGCTCTGTCTTCCACAAACAAAAATTCTGCCTTCAGACA TTTGGTGTTAGTATTTCACACTCAGTTCTCCCTTTTTTTACATAAGGATTGAGTTTCTTTTTATGATGATTTTACCTTTATAGCAATTTT GAATTTTGCATTCTATTGCTAGTATTGATTCAGGTACACCATTAAGATACAACATTCTAGAAGTCTATTACCTTAGGAGTTAATTAAACA TGATATTTGAAGAATAATGAAATGCTTTATAGTTGTTTGAGGCATAACAATGTGTATTTGTTTTACTGGATCATGTTTTGAACTGACTAG GGAGGGTAGCACCTGCCTCAGATAGTACCAACAATTCTGTTTCACTGGGTAGTCTAAAACTAGCTTATAGTTTAACTTAACTTGTTGTGT ATGTGAATTTAGGGATGGAAACTTTTTTTCCCCTATTTATTCTTTGTTTCCTTCTGGGAAAAAACCCCACAAAAATCAGCACTCCTTTAT GGATACATTGGAGCTTTTGAAAGAATTGTAAACTCTAGGAAGGGGAAATATCTGTGTCTTGATTTCTTAGTTGCCTTGAAAATCATGTAC TGAACTGTAACCGCTAACTTGACTGGATGAACTAGTTTGCTTGTGTGTAGAGAGTGTATTGCTTCCTCAGATTTCACTGTTTTCATCTCC TTTTCCATCTTAGTCTTTATTCCTTAAGACCAAAAACTGTAATATCCTTTAGAAATGCTCTAGAAGATCTGTATTGTGTAGAATGATCAT GTATTTATAAATATTTTACAAGTTTAGATTATAAAATGAAAAAGAAGGTCATGTGTTTTGGGGGGTATTTTGCATGTTCGGATTTTTTTT TCACTTCACCGAACCCTTCTGATTCTTTCAAACTATTGCCAGGTAGTTGTTAGTGTTTCTAATTGGACTCTTAATATGAACTTCAAGAAG CTGTTACCAGTTATCGGCTCTGTCATCTGAAATTTTAACCACTTAATTTAAAGTTACAATTTTAGAATTTGTTTTTGTTGTTTTACCTTA AGAAACACAATAAATCACTGTTTAAAAAAGATCTCAATTTATATAAAGTACTGGAAAAAAGCTAAGTAATTTTTAGTTCTATCTATAATC TCCGTAGGATGAATTAGAAATAAATTGTGATGAAAAGAAATTAACTGCTTATTTATGAATCTAATCATTTAGAAATGTCTGAGAGTAACA CTGCATTCTTATAGAAACAAAGCACAAATTGCATTCAAGCTCTGAATTGATTTTTTGCTTGGAGCTGTTGTTACAGTAGCTGTAATTTTG CTACCAGAATGTCTTAATTTTTTAAATTTGTTTTTATTTCTAAGCTCTTGGCAATGACAATAATTATAATTTTAACATATCTTCACTGTA GTCAACATGTAGAGTCTGCTTCCCTCATTATTGCATTGCTAAGGCCTTTTTAAAAAGCTTATGCTTACATAATATACTCTTTTTTATGGA CACGTTATATGTTTCCAAATCTGTGTATTGTGATTTTTACATACTAATGAATATAAACAGGTGATTTTAAAATATTACTGTGCTTCTTTG GTTGAATGAGCTGGTATTGATGTAAAATACTCTGTCATTGATGGACCACTACCTGCAGCTAAGCAGTGAGCAGAATCTCCGGGAAATGAC TTAGTCTGGCCACATGCATAGCCCATCTTCATAATGTCGCAGCAGAAGGTTCTTTGTGGTTAAAAGTTTTAAAGCCTATTTCTTTATAGG TAACCCTCTCAGGTATATTTACCTGGTAGAAAAACATGTAGATTGTTTCTATTACTTAAATGTTTTAATTGGACTGTAGTTTAGAAATTA CAGGACCAGCTTGTTACAGATTATACACTATTCTGTTACTTTTATTTCTGAAACTTAAAAACAATAAATTCTTTTTCTGTGTTTCTAGGT >In-frame_DECR1_ENST00000220764_chr8_91013789_+_STAU2_ENST00000517542_chr8_74464554_-_647nt TCCAGCCCCGAGAACTTTGTTCTTTTTGTCCCGCCCCCTGCGCCCAACCGCCTGCGCCGCCTTCCGGCCCGAGTTCTGGAGACTCAACAT GAAGCTACCGGCCAGGGTTTTCTTTACTCTGGGGTCCCGGCTGCCCTGTGGCCTCGCTCCTCGGAGGCTCCAAAAGGAATTCTTCATTTG TCTCCTGATGTTTATCAAGAGATGGAAGCCAGCCGCCACAAAGTAATCTCTGGCACTACTCTAGGCTATTTGTCACCCAAAGATATGAAC CAACCTTCAAGCTCTTTCTTCAGTATATCTCCCACATCGAATAGTTCAGCTACAATTGCCAGGGAACTCCTTATGAATGGAACATCTTCT ACAGCTGAAGCCATAGGTTTAAAAGGAAGTTCTCCTACTCCCCCTTGTTCTCCAGTACAACCTTCAAAACAACTGGAATATTTAGCAAGG ATTCAAGGCTTTCAGGTATGAATTAAAAGCAAAAACAAAAAACAAAACAATTCATTAGCCTCAGATTCTTCATCTGTATACATCACAAGG CTCATTCTTGCCTGCTAGTATGGCCTACATGCCACTTACGTTTTAAGTTATTTAGGAACACAAAGGACAGACAAAAAAGCCATATGCACA |
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FusionGenePPI for DECR1_STAU2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DECR1 | HGS, PTTG1, APP, ESR1, FN1, VCAM1, ITGA4, SHMT2, NXF1, NDUFA10, CREB3, ECSIT, NTRK1, HSD17B4, AK1, MSH6, JAK3, KIF11, NPM1, RPL10, BAIAP2, NOP56, GEMIN5, C10orf12, CCDC22, EXOSC5, NLRP5, NF2, FAM118B, CHMP2A | STAU2 | KIAA1377, DHX58, EIF2AK2, ELAVL1, COPS5, DICER1, PRKRA, UPF1, ZNF346, ADAR, SHMT2, MOV10, NXF1, BMI1, HIST1H1A, RPL14, RPL8, RPL6, NIFK, RPS2, PRR11, RBM4B, ILF2, PAIP1, HNRNPU, MATR3, STRBP, STAU1, GLTSCR2, WDR46, ELAVL2, PPAN, ZCRB1, ZC3HAV1, E4F1, DGCR8, ZNF324B, NXF2, CDX1, RPL37A, ZNF169, HIST1H1E, RPF1, ZNF2, GPATCH4, G3BP1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DECR1_STAU2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DECR1_STAU2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | DECR1 | C0009171 | Cocaine Abuse | 1 | PSYGENET |
| Hgene | DECR1 | C0023772 | Lipid Metabolism, Inborn Errors | 1 | CTD_human |
| Hgene | DECR1 | C1857252 | 2,4-Dienoyl-CoA Reductase Deficiency | 1 | CTD_human |
| Tgene | STAU2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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