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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 9426

FusionGeneSummary for DCLRE1C_NMT2

check button Fusion gene summary
Fusion gene informationFusion gene name: DCLRE1C_NMT2
Fusion gene ID: 9426
HgeneTgene
Gene symbol

DCLRE1C

NMT2

Gene ID

64421

9397

Gene nameDNA cross-link repair 1CN-myristoyltransferase 2
SynonymsA-SCID|DCLREC1C|RS-SCID|SCIDA|SNM1C-
Cytomap

10p13

10p13

Type of geneprotein-codingprotein-coding
Descriptionprotein artemisDNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)SNM1 homolog CSNM1-like proteinsevere combined immunodeficiency, type a (Athabascan)glycylpeptide N-tetradecanoyltransferase 2NMT 2glycylpeptide N-tetradecanoyltransferase 2 variant 3glycylpeptide N-tetradecanoyltransferase 2 variant 4myristoyl-CoA:protein N-myristoyltransferase 2peptide N-myristoyltransferase 2type II N-myristoylt
Modification date2018052320180523
UniProtAcc

Q96SD1

O60551

Ensembl transtripts involved in fusion geneENST00000378289, ENST00000453695, 
ENST00000378246, ENST00000357717, 
ENST00000378278, ENST00000396817, 
ENST00000378254, ENST00000378255, 
ENST00000378249, ENST00000378258, 
ENST00000378242, ENST00000492201, 
ENST00000378165, ENST00000378150, 
ENST00000535341, ENST00000466201, 
ENST00000540259, 
Fusion gene scores* DoF score2 X 2 X 2=83 X 3 X 3=27
# samples 23
** MAII scorelog2(2/8*10)=1.32192809488736log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: DCLRE1C [Title/Abstract] AND NMT2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNMT2

GO:0018008

N-terminal peptidyl-glycine N-myristoylation

25255805


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBLCATCGA-GV-A3JW-01ADCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000378289ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
In-frameENST00000378289ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
In-frameENST00000378289ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5CDS-intronENST00000378289ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5CDS-intronENST00000378289ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000453695ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000453695ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000453695ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000453695ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000453695ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378246ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378246ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378246ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378246ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378246ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000357717ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000357717ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000357717ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000357717ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000357717ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
In-frameENST00000378278ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
In-frameENST00000378278ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
In-frameENST00000378278ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5CDS-intronENST00000378278ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5CDS-intronENST00000378278ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000396817ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000396817ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000396817ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000396817ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000396817ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378254ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378254ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378254ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378254ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378254ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378255ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378255ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378255ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378255ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378255ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000378249ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000378249ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000378249ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-intronENST00000378249ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-intronENST00000378249ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378258ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378258ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-3CDSENST00000378258ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378258ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
5UTR-intronENST00000378258ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000378242ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000378242ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000378242ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-intronENST00000378242ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-intronENST00000378242ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000492201ENST00000378165DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000492201ENST00000378150DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-3CDSENST00000492201ENST00000535341DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-intronENST00000492201ENST00000466201DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-
intron-intronENST00000492201ENST00000540259DCLRE1Cchr10

14991035

-NMT2chr10

15170457

-

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FusionProtFeatures for DCLRE1C_NMT2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DCLRE1C

Q96SD1

NMT2

O60551

Adds a myristoyl group to the N-terminal glycine residueof certain cellular and viral proteins.{ECO:0000269|PubMed:25255805, ECO:0000269|PubMed:9506952}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNMT2chr10:14991035chr10:15170457ENST00000378165-61246_56296499Compositional biasNote=Poly-Lys
TgeneNMT2chr10:14991035chr10:15170457ENST00000378165-612120_122296499RegionMyristoyl-CoA binding
TgeneNMT2chr10:14991035chr10:15170457ENST00000378165-612250_252296499RegionMyristoyl-CoA binding
TgeneNMT2chr10:14991035chr10:15170457ENST00000378165-612258_262296499RegionMyristoyl-CoA binding


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FusionGeneSequence for DCLRE1C_NMT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000378165_chr10_15170457_-_256aa
MSSFEGQMAETPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPD
VTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFTTLPSTVMHHPAHKSLKAAYS

>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000378150_chr10_15170457_-_256aa
MSSFEGQMAETPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPD
VTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFTTLPSTVMHHPAHKSLKAAYS

>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000535341_chr10_15170457_-_256aa
MSSFEGQMAETPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPD
VTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFTTLPSTVMHHPAHKSLKAAYS

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000378165_chr10_15170457_-_256aa
MSSFEGQMAETPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPD
VTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFTTLPSTVMHHPAHKSLKAAYS

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000378150_chr10_15170457_-_256aa
MSSFEGQMAETPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPD
VTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFTTLPSTVMHHPAHKSLKAAYS

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000535341_chr10_15170457_-_256aa
MSSFEGQMAETPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPD
VTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFTTLPSTVMHHPAHKSLKAAYS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000378165_chr10_15170457_-_768nt
ATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTC
CTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTA
AACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGAT
GTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCAT
CTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAAC
GGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCA
TTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAAT
GCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGG

>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000378150_chr10_15170457_-_768nt
ATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTC
CTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTA
AACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGAT
GTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCAT
CTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAAC
GGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCA
TTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAAT
GCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGG

>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000535341_chr10_15170457_-_768nt
ATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTC
CTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTA
AACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGAT
GTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCAT
CTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAAC
GGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCA
TTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAAT
GCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGG

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000378165_chr10_15170457_-_768nt
ATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTC
CTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTA
AACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGAT
GTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCAT
CTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAAC
GGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCA
TTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAAT
GCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGG

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000378150_chr10_15170457_-_768nt
ATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTC
CTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTA
AACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGAT
GTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCAT
CTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAAC
GGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCA
TTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAAT
GCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGG

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000535341_chr10_15170457_-_768nt
ATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTC
CTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTA
AACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGAT
GTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCAT
CTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAAC
GGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCA
TTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAAT
GCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGG


* Fusion transcript sequences (Full-length transcript).
>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000378165_chr10_15170457_-_2519nt
CGGAACGAAGAATGATTTCTAAGCGCAGTTCCGCAGCCCACTCACCTCGTCGGCTGGGGCCACCTGCTCTGGGAGTTTCGATTTCCCTTC
CCGCGACTGCACCTCCACAGACATGGGCAACGCCTTACCAGAGCAACACCTGTGTTTGTTGGGCGGGAATGAGCCTTGCACTGGGCAGGG
CTCAGGGCCCATCGCGTGCAGCGAAGCGCGGGTGATTTAAACCCAAGCAGCGGGCGCCTAGAACCCGACCGGATGCTCCTTGACTTTGCC
CCCGGTCTCCGGACTCCTCTGATTGGACGTGGCTGCGTTCGGCCGCCCAATGGCGAGGCAGCGCGCGGCTTCCCGGAAGTGGCGGCGCGG
TCAGGGCTGGCCTTGGCTTCAGCTGCGGTTTTGGGGTCCCGGACTCTGGGATCGGCGGCGCTATGAGTTCTTTCGAGGGGCAGATGGCCG
AGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTCCTGTCCCACTGCCACAAAGATCACATGA
AAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTAGAAGTGAAAT
TTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAA
TGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGATGAAGAGGAAG
TAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCT
ATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACAGAGACGCCCC
TGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAATGCACTGGATTTGATGGAAAATAAGACAT
TCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGATTCTGAAAAGG
TTGGACTAGTACTACAATAGATGGATATTTTTATTTCTAGAACTCTGACATCATCATTTGTTAATATTTAATGATTTCTGGAACTGCCAT
TCCAAAGAAGAATAAAAGCACAACTCAAGTGAAATTGAAGTAGTCGATAATCAGAAAAGATGACAAAAGTCCACATGTGACATTTGTACG
TTTCTAGCTAGAATGTTAAACTTCATCCTTTTTTTACTGTTGACCTATTTGTGGGAGGGATGAAAGGCTACAAAGAGCACATTCTTGTAA
TTTTCAAATTTTTGCCTGTCTCTTGAAGAGGTATTTTTTCACCCTTAGAAAAGGGACTGTTTTTCTATGGACTAAGTAGAAGTTACAGAG
TCATGTAAGAAAATCTTTGCTATTGTGTGGAGAGAAATTGCTGCATTTCTGTTTCTTAAGTGATGGTACATTTGTCCATGTAACAGAACA
AAAGATCCATTTGGAAATTTTTTTTACTGGTATCACCTTACATGGTATCACTGGGAACATTTATGGAATCAACACTTCTGTAGCTCAGTG
ACAGGTGGTGGTTGTTTAAGTGCAGAGCAATATTAAAATGTACTGGTGACTAGTACATGTATTTCTCCATAAGCAGAGTTGCCGAATCAA
TAAACATGCAAGTTTGTACTTTGATCTTTACCAGGTCAGTGGATTGCTTCAAAAGCAGAGTTTTGTGCAAGCACTCACTGTGCTCTCTGA
AAGAGCCTGAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCATGAGGTCAGGAGATCGA
GACCATTCTGGCCAACATAGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCGTGTGCCTGTAGTCCCAGCTG
CTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGAGAGGTGAGGTTGCAGTGAGCCGAGATCGAGCCACTGCACTCCAGCCTGGGTGA
CAGAGCGTGAGACTCCGTCTCAAAAAAAAAAAAAAAGAAAGAGCCTGTACCCGCGACTAACTAGACTTTTCTGCTGTTGTGCAAAGTTCA
GTTTCTTCTCAGCAACATCAAGGATATATGAAGAAAAGGAAATAAAAAACTGTAAAGTCAAAAGAGATGCCTGGTGGAACTTATTCGTGC
TATCAGGGCATTGATAGTTTGAATGTTTTTATTACTTATGCAAAATTGCACATACTCCTCTATGCTGATTTTATCATGAAAACTGTCATG

>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000378150_chr10_15170457_-_2091nt
CGGAACGAAGAATGATTTCTAAGCGCAGTTCCGCAGCCCACTCACCTCGTCGGCTGGGGCCACCTGCTCTGGGAGTTTCGATTTCCCTTC
CCGCGACTGCACCTCCACAGACATGGGCAACGCCTTACCAGAGCAACACCTGTGTTTGTTGGGCGGGAATGAGCCTTGCACTGGGCAGGG
CTCAGGGCCCATCGCGTGCAGCGAAGCGCGGGTGATTTAAACCCAAGCAGCGGGCGCCTAGAACCCGACCGGATGCTCCTTGACTTTGCC
CCCGGTCTCCGGACTCCTCTGATTGGACGTGGCTGCGTTCGGCCGCCCAATGGCGAGGCAGCGCGCGGCTTCCCGGAAGTGGCGGCGCGG
TCAGGGCTGGCCTTGGCTTCAGCTGCGGTTTTGGGGTCCCGGACTCTGGGATCGGCGGCGCTATGAGTTCTTTCGAGGGGCAGATGGCCG
AGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTCCTGTCCCACTGCCACAAAGATCACATGA
AAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTAGAAGTGAAAT
TTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAA
TGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGATGAAGAGGAAG
TAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCT
ATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACAGAGACGCCCC
TGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAATGCACTGGATTTGATGGAAAATAAGACAT
TCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGATTCTGAAAAGG
TTGGACTAGTACTACAATAGATGGATATTTTTATTTCTAGAACTCTGACATCATCATTTGTTAATATTTAATGATTTCTGGAACTGCCAT
TCCAAAGAAGAATAAAAGCACAACTCAAGTGAAATTGAAGTAGTCGATAATCAGAAAAGATGACAAAAGTCCACATGTGACATTTGTACG
TTTCTAGCTAGAATGTTAAACTTCATCCTTTTTTTACTGTTGACCTATTTGTGGGAGGGATGAAAGGCTACAAAGAGCACATTCTTGTAA
TTTTCAAATTTTTGCCTGTCTCTTGAAGAGGTATTTTTTCACCCTTAGAAAAGGGACTGTTTTTCTATGGACTAAGTAGAAGTTACAGAG
TCATGTAAGAAAATCTTTGCTATTGTGTGGAGAGAAATTGCTGCATTTCTGTTTCTTAAGTGATGGTACATTTGTCCATGTAACAGAACA
AAAGATCCATTTGGAAATTTTTTTTACTGGTATCACCTTACATGGTATCACTGGGAACATTTATGGAATCAACACTTCTGTAGCTCAGTG
ACAGGTGGTGGTTGTTTAAGTGCAGAGCAATATTAAAATGTACTGGTGACTAGTACATGTATTTCTCCATAAGCAGAGTTGCCGAATCAA
TAAACATGCAAGTTTGTACTTTGATCTTTACCAGGTCAGTGGATTGCTTCAAAAGCAGAGTTTTGTGCAAGCACTCACTGTGCTCTCTGA
AAGAGCCTGAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCATGAGGTCAGGAGATCGA
GACCATTCTGGCCAACATAGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCGTGTGCCTGTAGTCCCAGCTG

>In-frame_DCLRE1C_ENST00000378289_chr10_14991035_-_NMT2_ENST00000535341_chr10_15170457_-_1286nt
CGGAACGAAGAATGATTTCTAAGCGCAGTTCCGCAGCCCACTCACCTCGTCGGCTGGGGCCACCTGCTCTGGGAGTTTCGATTTCCCTTC
CCGCGACTGCACCTCCACAGACATGGGCAACGCCTTACCAGAGCAACACCTGTGTTTGTTGGGCGGGAATGAGCCTTGCACTGGGCAGGG
CTCAGGGCCCATCGCGTGCAGCGAAGCGCGGGTGATTTAAACCCAAGCAGCGGGCGCCTAGAACCCGACCGGATGCTCCTTGACTTTGCC
CCCGGTCTCCGGACTCCTCTGATTGGACGTGGCTGCGTTCGGCCGCCCAATGGCGAGGCAGCGCGCGGCTTCCCGGAAGTGGCGGCGCGG
TCAGGGCTGGCCTTGGCTTCAGCTGCGGTTTTGGGGTCCCGGACTCTGGGATCGGCGGCGCTATGAGTTCTTTCGAGGGGCAGATGGCCG
AGTATCCAACTATCTCCATAGACCGCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTCCTGTCCCACTGCCACAAAGATCACATGA
AAGGATTAAGAGCCCCTACCTTGAAAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTAGAAGTGAAAT
TTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATACAGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAA
TGGAACCAAAAGATATCAAATCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGATGAAGAGGAAG
TAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCT
ATACGCTCCCCTCCACGGTGATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACAGAGACGCCCC
TGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAATGCACTGGATTTGATGGAAAATAAGACAT
TCTTGGAAAAACTCAAGTTTGGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGATTCTGAAAAGG
TTGGACTAGTACTACAATAGATGGATATTTTTATTTCTAGAACTCTGACATCATCATTTGTTAATATTTAATGATTTCTGGAACTGCCAT

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000378165_chr10_15170457_-_2135nt
GCGGTTTTGGGGTCCCGGACTCTGGGATCGGCGGCGCTATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACC
GCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTCCTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGA
AAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGA
CTTTACAGAGAACAATGAAGCTATACAGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAG
TTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGG
AGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGC
ACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGC
TCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAATGCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTA
TAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGATTCTGAAAAGGTTGGACTAGTACTACAATAGATGG
ATATTTTTATTTCTAGAACTCTGACATCATCATTTGTTAATATTTAATGATTTCTGGAACTGCCATTCCAAAGAAGAATAAAAGCACAAC
TCAAGTGAAATTGAAGTAGTCGATAATCAGAAAAGATGACAAAAGTCCACATGTGACATTTGTACGTTTCTAGCTAGAATGTTAAACTTC
ATCCTTTTTTTACTGTTGACCTATTTGTGGGAGGGATGAAAGGCTACAAAGAGCACATTCTTGTAATTTTCAAATTTTTGCCTGTCTCTT
GAAGAGGTATTTTTTCACCCTTAGAAAAGGGACTGTTTTTCTATGGACTAAGTAGAAGTTACAGAGTCATGTAAGAAAATCTTTGCTATT
GTGTGGAGAGAAATTGCTGCATTTCTGTTTCTTAAGTGATGGTACATTTGTCCATGTAACAGAACAAAAGATCCATTTGGAAATTTTTTT
TACTGGTATCACCTTACATGGTATCACTGGGAACATTTATGGAATCAACACTTCTGTAGCTCAGTGACAGGTGGTGGTTGTTTAAGTGCA
GAGCAATATTAAAATGTACTGGTGACTAGTACATGTATTTCTCCATAAGCAGAGTTGCCGAATCAATAAACATGCAAGTTTGTACTTTGA
TCTTTACCAGGTCAGTGGATTGCTTCAAAAGCAGAGTTTTGTGCAAGCACTCACTGTGCTCTCTGAAAGAGCCTGAGGCCGGGCGTGGTG
GCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCATGAGGTCAGGAGATCGAGACCATTCTGGCCAACATAGTGAA
ACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCGTGTGCCTGTAGTCCCAGCTGCTTGGGAGGCTGAGGCAGGAGAAT
CGCTTGAACCTGAGAGGTGAGGTTGCAGTGAGCCGAGATCGAGCCACTGCACTCCAGCCTGGGTGACAGAGCGTGAGACTCCGTCTCAAA
AAAAAAAAAAAAGAAAGAGCCTGTACCCGCGACTAACTAGACTTTTCTGCTGTTGTGCAAAGTTCAGTTTCTTCTCAGCAACATCAAGGA
TATATGAAGAAAAGGAAATAAAAAACTGTAAAGTCAAAAGAGATGCCTGGTGGAACTTATTCGTGCTATCAGGGCATTGATAGTTTGAAT
GTTTTTATTACTTATGCAAAATTGCACATACTCCTCTATGCTGATTTTATCATGAAAACTGTCATGTGTCATGCTAATGGAAAATGTCTT

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000378150_chr10_15170457_-_1707nt
GCGGTTTTGGGGTCCCGGACTCTGGGATCGGCGGCGCTATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACC
GCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTCCTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGA
AAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGA
CTTTACAGAGAACAATGAAGCTATACAGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAG
TTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGG
AGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGC
ACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGC
TCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAATGCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTA
TAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGATTCTGAAAAGGTTGGACTAGTACTACAATAGATGG
ATATTTTTATTTCTAGAACTCTGACATCATCATTTGTTAATATTTAATGATTTCTGGAACTGCCATTCCAAAGAAGAATAAAAGCACAAC
TCAAGTGAAATTGAAGTAGTCGATAATCAGAAAAGATGACAAAAGTCCACATGTGACATTTGTACGTTTCTAGCTAGAATGTTAAACTTC
ATCCTTTTTTTACTGTTGACCTATTTGTGGGAGGGATGAAAGGCTACAAAGAGCACATTCTTGTAATTTTCAAATTTTTGCCTGTCTCTT
GAAGAGGTATTTTTTCACCCTTAGAAAAGGGACTGTTTTTCTATGGACTAAGTAGAAGTTACAGAGTCATGTAAGAAAATCTTTGCTATT
GTGTGGAGAGAAATTGCTGCATTTCTGTTTCTTAAGTGATGGTACATTTGTCCATGTAACAGAACAAAAGATCCATTTGGAAATTTTTTT
TACTGGTATCACCTTACATGGTATCACTGGGAACATTTATGGAATCAACACTTCTGTAGCTCAGTGACAGGTGGTGGTTGTTTAAGTGCA
GAGCAATATTAAAATGTACTGGTGACTAGTACATGTATTTCTCCATAAGCAGAGTTGCCGAATCAATAAACATGCAAGTTTGTACTTTGA
TCTTTACCAGGTCAGTGGATTGCTTCAAAAGCAGAGTTTTGTGCAAGCACTCACTGTGCTCTCTGAAAGAGCCTGAGGCCGGGCGTGGTG
GCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCATGAGGTCAGGAGATCGAGACCATTCTGGCCAACATAGTGAA

>In-frame_DCLRE1C_ENST00000378278_chr10_14991035_-_NMT2_ENST00000535341_chr10_15170457_-_902nt
GCGGTTTTGGGGTCCCGGACTCTGGGATCGGCGGCGCTATGAGTTCTTTCGAGGGGCAGATGGCCGAGTATCCAACTATCTCCATAGACC
GCTTCGATAGGGAGAACCTGAGGGCCCGCGCCTACTTCCTGTCCCACTGCCACAAAGATCACATGAAAGGATTAAGAGCCCCTACCTTGA
AAAGAAGGTTGGAGTGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTAGAAGTGAAATTTTCTCACTTGAGTAGAAATATGA
CTTTACAGAGAACAATGAAGCTATACAGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAATCAG
TTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGATGAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGG
AGCACATTATTGACACGTTTGTAGTGGAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTGATGC
ACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACAGAGACGCCCCTGCTGGACCTCATGAGCGACGCGC
TCATCCTGGCTAAATCGAAAGGATTTGATGTATTCAATGCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTTGGTA
TAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGATTCTGAAAAGGTTGGACTAGTACTACAATAGATGG
ATATTTTTATTTCTAGAACTCTGACATCATCATTTGTTAATATTTAATGATTTCTGGAACTGCCATTCCAAAGAAGAATAAAAGCACAAC


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FusionGenePPI for DCLRE1C_NMT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
DCLRE1CPRKDC, FBXW7, DDB1, DDB2, ATM, BRCA1, RAD50, NBN, MRE11A, ATR, XRCC5, CDKN1B, AKAP11, ANKRD52, ZSWIM8, PRKAG2, PRKAG1, PPP6R2, PRKAB1, PRKAB2, TRIM26, PRKACB, PRKAA1, PRKAA2, PASK, ANKRD28, DDX20, PPP6R1, GOLGA2, SPATA20, CDC27, PRKAR1B, PPP2R5E, TP53, MTHFRNMT2ANXA4, CSNK2B, PRKCZ, TK1, SMN1, ANXA7, APP, PPP1CC, TMED9, TP53, BCL2, FBXO17, ODF3L2, FAM84B, PRPS2, PRPS1, TGFB1, GFOD1, ZNRF1, GPRC5C, ASB6, NCS1, MARCKSL1, ANGPTL4, AIFM3, TLDC1, MGST3, DEFB1, FAM109B, FAM45A


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for DCLRE1C_NMT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for DCLRE1C_NMT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDCLRE1CC1865370Severe combined immunodeficiency with sensitivity to ionizing radiation1CTD_human;ORPHANET;UNIPROT
HgeneDCLRE1CC2700553Omenn Syndrome1ORPHANET;UNIPROT
TgeneNMT2C0029927Ovarian Cysts1CTD_human