	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 9390

FusionGeneSummary for DCAF8_DCAF8

Fusion gene summary

Fusion gene information	Fusion gene name: DCAF8_DCAF8
	Fusion gene ID: 9390
		Hgene	Tgene
	Gene symbol	DCAF8	DCAF8
	Gene ID	50717	50717
	Gene name	DDB1 and CUL4 associated factor 8	DDB1 and CUL4 associated factor 8
	Synonyms	GAN2\|H326\|WDR42A	GAN2\|H326\|WDR42A
	Cytomap	1q23.2	1q23.2
	Type of gene	protein-coding	protein-coding
	Description	DDB1- and CUL4-associated factor 8WD repeat domain 42AWD repeat-containing protein 42A	DDB1- and CUL4-associated factor 8WD repeat domain 42AWD repeat-containing protein 42A
	Modification date	20180519	20180519
	UniProtAcc	Q5TAQ9	Q5TAQ9
	Ensembl transtripts involved in fusion gene	ENST00000368073, ENST00000326837, ENST00000368074, ENST00000608310, ENST00000556710, ENST00000610139, ENST00000475733,	ENST00000368073, ENST00000326837, ENST00000368074, ENST00000608310, ENST00000556710, ENST00000610139, ENST00000475733,
Fusion gene scores	* DoF score	8 X 9 X 5=360	9 X 12 X 4=432
	# samples	13	14
	** MAII score	log2(13/360*10)=-1.46948528330122 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(14/432*10)=-1.6256044852185 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: DCAF8 [Title/Abstract] AND DCAF8 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			BI963970	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
ChiTaRS3.1			BG178531	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
ChiTaRS3.1			AA632582	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
ChiTaRS3.1			CA450406	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
ChiTaRS3.1			BI964144	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
ChiTaRS3.1			CK903773	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-intron	ENST00000368073	ENST00000368073	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368073	ENST00000326837	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368073	ENST00000368074	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368073	ENST00000608310	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368073	ENST00000556710	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368073	ENST00000610139	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368073	ENST00000475733	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000326837	ENST00000368073	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000326837	ENST00000326837	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000326837	ENST00000368074	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000326837	ENST00000608310	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000326837	ENST00000556710	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000326837	ENST00000610139	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000326837	ENST00000475733	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368074	ENST00000368073	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368074	ENST00000326837	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368074	ENST00000368074	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368074	ENST00000608310	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368074	ENST00000556710	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368074	ENST00000610139	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000368074	ENST00000475733	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000608310	ENST00000368073	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000608310	ENST00000326837	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000608310	ENST00000368074	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000608310	ENST00000608310	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000608310	ENST00000556710	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000608310	ENST00000610139	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000608310	ENST00000475733	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000556710	ENST00000368073	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000556710	ENST00000326837	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000556710	ENST00000368074	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000556710	ENST00000608310	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000556710	ENST00000556710	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000556710	ENST00000610139	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000556710	ENST00000475733	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000610139	ENST00000368073	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000610139	ENST00000326837	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000610139	ENST00000368074	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000610139	ENST00000608310	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000610139	ENST00000556710	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000610139	ENST00000610139	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000610139	ENST00000475733	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000475733	ENST00000368073	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000475733	ENST00000326837	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000475733	ENST00000368074	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000475733	ENST00000608310	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000475733	ENST00000556710	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000475733	ENST00000610139	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-intron	ENST00000475733	ENST00000475733	DCAF8	chr1	160248555	-	DCAF8	chr1	160249214	-
intron-3UTR	ENST00000368073	ENST00000368073	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000368073	ENST00000326837	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000368073	ENST00000368074	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368073	ENST00000608310	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368073	ENST00000556710	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368073	ENST00000610139	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368073	ENST00000475733	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000326837	ENST00000368073	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000326837	ENST00000326837	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000326837	ENST00000368074	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000326837	ENST00000608310	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000326837	ENST00000556710	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000326837	ENST00000610139	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000326837	ENST00000475733	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000368074	ENST00000368073	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000368074	ENST00000326837	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000368074	ENST00000368074	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368074	ENST00000608310	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368074	ENST00000556710	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368074	ENST00000610139	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368074	ENST00000475733	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000608310	ENST00000368073	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000608310	ENST00000326837	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000608310	ENST00000368074	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000608310	ENST00000608310	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000608310	ENST00000556710	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000608310	ENST00000610139	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000608310	ENST00000475733	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000556710	ENST00000368073	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000556710	ENST00000326837	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000556710	ENST00000368074	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000556710	ENST00000608310	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000556710	ENST00000556710	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000556710	ENST00000610139	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000556710	ENST00000475733	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000610139	ENST00000368073	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000610139	ENST00000326837	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000610139	ENST00000368074	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000610139	ENST00000608310	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000610139	ENST00000556710	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000610139	ENST00000610139	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000610139	ENST00000475733	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000475733	ENST00000368073	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000475733	ENST00000326837	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-3UTR	ENST00000475733	ENST00000368074	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000475733	ENST00000608310	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000475733	ENST00000556710	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000475733	ENST00000610139	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000475733	ENST00000475733	DCAF8	chr1	160185740	+	DCAF8	chr1	160185696	-
intron-intron	ENST00000368073	ENST00000368073	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368073	ENST00000326837	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368073	ENST00000368074	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368073	ENST00000608310	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368073	ENST00000556710	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368073	ENST00000610139	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368073	ENST00000475733	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000326837	ENST00000368073	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000326837	ENST00000326837	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000326837	ENST00000368074	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000326837	ENST00000608310	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000326837	ENST00000556710	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000326837	ENST00000610139	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000326837	ENST00000475733	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368074	ENST00000368073	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368074	ENST00000326837	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368074	ENST00000368074	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368074	ENST00000608310	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368074	ENST00000556710	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368074	ENST00000610139	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368074	ENST00000475733	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000608310	ENST00000368073	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000608310	ENST00000326837	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000608310	ENST00000368074	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000608310	ENST00000608310	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000608310	ENST00000556710	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000608310	ENST00000610139	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000608310	ENST00000475733	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000556710	ENST00000368073	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000556710	ENST00000326837	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000556710	ENST00000368074	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000556710	ENST00000608310	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000556710	ENST00000556710	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000556710	ENST00000610139	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000556710	ENST00000475733	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000610139	ENST00000368073	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000610139	ENST00000326837	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000610139	ENST00000368074	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000610139	ENST00000608310	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000610139	ENST00000556710	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000610139	ENST00000610139	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000610139	ENST00000475733	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000475733	ENST00000368073	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000475733	ENST00000326837	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000475733	ENST00000368074	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000475733	ENST00000608310	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000475733	ENST00000556710	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000475733	ENST00000610139	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000475733	ENST00000475733	DCAF8	chr1	160248913	-	DCAF8	chr1	160248772	+
intron-intron	ENST00000368073	ENST00000368073	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368073	ENST00000326837	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368073	ENST00000368074	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368073	ENST00000608310	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368073	ENST00000556710	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368073	ENST00000610139	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368073	ENST00000475733	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000326837	ENST00000368073	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000326837	ENST00000326837	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000326837	ENST00000368074	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000326837	ENST00000608310	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000326837	ENST00000556710	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000326837	ENST00000610139	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000326837	ENST00000475733	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368074	ENST00000368073	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368074	ENST00000326837	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368074	ENST00000368074	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368074	ENST00000608310	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368074	ENST00000556710	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368074	ENST00000610139	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000368074	ENST00000475733	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000608310	ENST00000368073	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000608310	ENST00000326837	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000608310	ENST00000368074	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000608310	ENST00000608310	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000608310	ENST00000556710	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000608310	ENST00000610139	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000608310	ENST00000475733	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000556710	ENST00000368073	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000556710	ENST00000326837	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000556710	ENST00000368074	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000556710	ENST00000608310	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000556710	ENST00000556710	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000556710	ENST00000610139	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000556710	ENST00000475733	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000610139	ENST00000368073	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000610139	ENST00000326837	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000610139	ENST00000368074	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000610139	ENST00000608310	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000610139	ENST00000556710	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000610139	ENST00000610139	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000610139	ENST00000475733	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000475733	ENST00000368073	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000475733	ENST00000326837	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000475733	ENST00000368074	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000475733	ENST00000608310	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000475733	ENST00000556710	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000475733	ENST00000610139	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-
intron-intron	ENST00000475733	ENST00000475733	DCAF8	chr1	160248120	+	DCAF8	chr1	160248176	-

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FusionProtFeatures for DCAF8_DCAF8

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
DCAF8 Q5TAQ9	DCAF8 Q5TAQ9
May function as a substrate receptor for CUL4-DDB1 E3ubiquitin-protein ligase complex. {ECO:0000269\|PubMed:16949367,ECO:0000269\|PubMed:16964240}.	May function as a substrate receptor for CUL4-DDB1 E3ubiquitin-protein ligase complex. {ECO:0000269\|PubMed:16949367,ECO:0000269\|PubMed:16964240}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for DCAF8_DCAF8

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for DCAF8_DCAF8

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for DCAF8_DCAF8

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for DCAF8_DCAF8

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	DCAF8	C4013360	GIANT AXONAL NEUROPATHY 2, AUTOSOMAL DOMINANT	1	ORPHANET;UNIPROT
Tgene	DCAF8	C4013360	GIANT AXONAL NEUROPATHY 2, AUTOSOMAL DOMINANT	1	ORPHANET;UNIPROT

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Fusion gene ID: 9390

FusionGeneSummary for DCAF8_DCAF8

FusionProtFeatures for DCAF8_DCAF8

FusionGeneSequence for DCAF8_DCAF8

FusionGenePPI for DCAF8_DCAF8

RelatedDrugs for DCAF8_DCAF8

RelatedDiseases for DCAF8_DCAF8