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Fusion gene ID: 8994 |
FusionGeneSummary for CUL4B_DAPK2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CUL4B_DAPK2 | Fusion gene ID: 8994 | Hgene | Tgene | Gene symbol | CUL4B | DAPK2 | Gene ID | 8450 | 23604 |
| Gene name | cullin 4B | death associated protein kinase 2 | |
| Synonyms | CUL-4B|MRXHF2|MRXS15|MRXSC|SFM2 | DRP-1|DRP1 | |
| Cytomap | Xq24 | 15q22.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cullin-4B | death-associated protein kinase 2DAP kinase 2DAP-kinase-related protein 1 beta isoform | |
| Modification date | 20180523 | 20180526 | |
| UniProtAcc | Q13620 | Q9UIK4 | |
| Ensembl transtripts involved in fusion gene | ENST00000371322, ENST00000336592, ENST00000404115, ENST00000486604, | ENST00000261891, ENST00000457488, ENST00000558069, ENST00000558482, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 6 X 7 X 7=294 |
| # samples | 2 | 10 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(10/294*10)=-1.55581615506164 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CUL4B [Title/Abstract] AND DAPK2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CUL4B | GO:0010498 | proteasomal protein catabolic process | 25970626 |
| Hgene | CUL4B | GO:0035518 | histone H2A monoubiquitination | 22334663 |
| Hgene | CUL4B | GO:0070914 | UV-damage excision repair | 22334663 |
| Tgene | DAPK2 | GO:0006468 | protein phosphorylation | 10376525 |
| Tgene | DAPK2 | GO:0035556 | intracellular signal transduction | 10376525 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LIHC | TCGA-DD-A11C-01A | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000371322 | ENST00000261891 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| Frame-shift | ENST00000371322 | ENST00000457488 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| Frame-shift | ENST00000371322 | ENST00000558069 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| 5CDS-5UTR | ENST00000371322 | ENST00000558482 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| Frame-shift | ENST00000336592 | ENST00000261891 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| Frame-shift | ENST00000336592 | ENST00000457488 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| Frame-shift | ENST00000336592 | ENST00000558069 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| 5CDS-5UTR | ENST00000336592 | ENST00000558482 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| In-frame | ENST00000404115 | ENST00000261891 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| In-frame | ENST00000404115 | ENST00000457488 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| In-frame | ENST00000404115 | ENST00000558069 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| 5CDS-5UTR | ENST00000404115 | ENST00000558482 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| intron-3CDS | ENST00000486604 | ENST00000261891 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| intron-3CDS | ENST00000486604 | ENST00000457488 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| intron-3CDS | ENST00000486604 | ENST00000558069 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
| intron-5UTR | ENST00000486604 | ENST00000558482 | CUL4B | chrX | 119691779 | - | DAPK2 | chr15 | 64275953 | - |
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FusionProtFeatures for CUL4B_DAPK2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CUL4B | DAPK2 |
| Calcium/calmodulin-dependent serine/threonine kinaseinvolved in multiple cellular signaling pathways that trigger cellsurvival, apoptosis, and autophagy. Regulates both type Iapoptotic and type II autophagic cell death signals, depending onthe cellular setting. The former is caspase-dependent, while thelatter is caspase-independent and is characterized by theaccumulation of autophagic vesicles. Acts as a mediator of anoikisand a suppressor of beta-catenin-dependent anchorage-independentgrowth of malignant epithelial cells. May play a role ingranulocytic maturation (PubMed:17347302). Regulates granulocyticmotility by controlling cell spreading and polarization(PubMed:24163421). {ECO:0000269|PubMed:17347302,ECO:0000269|PubMed:24163421, ECO:0000269|PubMed:26047703}. Isoform 2 is not regulated by calmodulin. It canphosphorylate MYL9. It can induce membrane blebbing and autophagiccell death. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for CUL4B_DAPK2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000261891_chr15_64275953_-_582aa MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQP RDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQWPVCHREEVPGEEHGAXVCSQVHQEAAE PGEPARCEPGGDRAGGEHPAAGAAPQCHHAARRLXEPHRRGAHPXASVWRRALRFPGPEGVTEXGGGHQLHXADPGWGELPSHKENCSLX SQARKHYVVRQEYSHSTHQADXLWSGSRNRRWSXIXEYFWDAGICCSRNCELRAPGSGGXHVEHRRHHLHPLKWSIPFPGRHEAGNTGKY HSSELRLXXGILQPDERAGQGLYSEASGXRDPETAHNPRGSQTPLDHAGGQPASHGAQGVCGQSGELQEAVCPQAVEAFLQHRVPVQPPH >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000457488_chr15_64275953_-_582aa MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQP RDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQWPVCHREEVPGEEHGAXVCSQVHQEAAE PGEPARCEPGGDRAGGEHPAAGAAPQCHHAARRLXEPHRRGAHPXASVWRRALRFPGPEGVTEXGGGHQLHXADPGWGELPSHKENCSLX SQARKHYVVRQEYSHSTHQADXLWSGSRNRRWSXIXEYFWDAGICCSRNCELRAPGSGGXHVEHRRHHLHPLKWSIPFPGRHEAGNTGKY HSSELRLXXGILQPDERAGQGLYSEASGXRDPETAHNPRGSQTPLDHAGGQPASHGAQGVCGQSGELQEAVCPQAVEAFLQHRVPVQPPH >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000558069_chr15_64275953_-_700aa MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQP RDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQWPVCHREEVPGEEHGAXVCSQVHQEAAE PGEPARCEPGGDRAGGEHPAAGAAPQCHHAARRLXEPHRRGAHPXASVWRRALRFPGPEGVTEXGGGHQLHXADPGWGELPSHKENCSLX SQARKHYVVRQEYSHSTHQADXLWSGSRNRRWSXIXEYFWDAGICCSRNCELRAPGSGGXHVEHRRHHLHPLKWSIPFPGRHEAGNTGKY HSSELRLXXGILQPDERAGQGLYSEASGXRDPETAHNPRGSQTPLDHVKRRRQSPXTAEDRAHPAEDQAPERVHSQMPLKHASQQLLCQL RAFCLCGGRRGSGRPGMPCPGGGPRYHPGRCGGPGLHLQXEGSLVPRGEXERPAXPVPAQVXVPQGGVIEEAAARRHPGHGMXPRKHGQE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000261891_chr15_64275953_-_1747nt ATGATGTCACAGTCATCTGGATCAGGAGATGGGAATGATGATGAGGCTACTACCTCTAAAGACGGTGGTTTTTCTTCCCCCAGTCCCTCA GCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACCAGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAAC AGCAGCAGCAGTAGCAGCAGTAACAGTAGTAACGAGAGAGAAGACTTTGATTCCACCTCTTCCTCCTCTTCCACTCCTCCTTTACAACCC AGGGATTCGGCATCCCCTTCAACCTCGTCCTTCTGCCTGGGGGTTTCAGTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAGCTGCGT TTTGAAGACACCCTGGAGTTTGTAGGGTTTGATGCGAAGATGGCTGAGGAATCCTCCTCCTCCTCCTCCTCATCTTCACCAACTGCTGCA ACATCTCAGCAGCAGCAACTTAAAAATAAGAGTATATTAATCTCTTCTGTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAATCTTCT ACCACCGTCTCTAGCTTTGCTAACAGCAAACCTGGCTCTGCTAAGAAGTTAGTGATCAAGAACTTTAAAGATAAGCCTAAATTACCAGAA AACTACACAGATGAAACCTGGCAAAAACTGAAAGAAGCAGTGGAAGCTATTCAGAATAGTACTTCAATTAAGTACAATTTAGAAGAACTC TACCAGTGGCCAGTTTGCCATCGTGAAGAAGTGCCGGGAGAAGAGCACGGGGCTTGAGTATGCAGCCAAGTTCATCAAGAAGCGGCAGAG CCGGGCGAGCCGGCGCGGTGTGAGCCGGGAGGAGATCGAGCGGGAGGTGAGCATCCTGCGGCAGGTGCTGCACCACAATGTCATCACGCT GCACGACGTCTATGAGAACCGCACCGACGTGGTGCTCATCCTTGAGCTAGTGTCTGGAGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGA GTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAACTACCTTCACACAAAGAAAATTGCTCACTTTGA TCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAAGCTGATTGACTTTGGTCTGGCTCACGAAATAGA AGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAATTGTGAACTACGAGCCCCTGGGTCTGGAGGCTGA CATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCTGGGAGACACGAAGCAGGAAACACTGGCAAATAT CACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGCCAAGGACTTTATTCGGAAGCTTCTGGTTAAAGA GACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGCCGGTGGACAACCAGCAAGCCATGGTGCGCAGGGAGTC TGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTGGAAGCTTTCCTTCAGCATCGTGTCCCTGTGCAACCACCTCAC CCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAGGAACTGTGAGAGTGACACTGAGGAGGACATCGCCAGGAGGAA >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000457488_chr15_64275953_-_1747nt ATGATGTCACAGTCATCTGGATCAGGAGATGGGAATGATGATGAGGCTACTACCTCTAAAGACGGTGGTTTTTCTTCCCCCAGTCCCTCA GCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACCAGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAAC AGCAGCAGCAGTAGCAGCAGTAACAGTAGTAACGAGAGAGAAGACTTTGATTCCACCTCTTCCTCCTCTTCCACTCCTCCTTTACAACCC AGGGATTCGGCATCCCCTTCAACCTCGTCCTTCTGCCTGGGGGTTTCAGTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAGCTGCGT TTTGAAGACACCCTGGAGTTTGTAGGGTTTGATGCGAAGATGGCTGAGGAATCCTCCTCCTCCTCCTCCTCATCTTCACCAACTGCTGCA ACATCTCAGCAGCAGCAACTTAAAAATAAGAGTATATTAATCTCTTCTGTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAATCTTCT ACCACCGTCTCTAGCTTTGCTAACAGCAAACCTGGCTCTGCTAAGAAGTTAGTGATCAAGAACTTTAAAGATAAGCCTAAATTACCAGAA AACTACACAGATGAAACCTGGCAAAAACTGAAAGAAGCAGTGGAAGCTATTCAGAATAGTACTTCAATTAAGTACAATTTAGAAGAACTC TACCAGTGGCCAGTTTGCCATCGTGAAGAAGTGCCGGGAGAAGAGCACGGGGCTTGAGTATGCAGCCAAGTTCATCAAGAAGCGGCAGAG CCGGGCGAGCCGGCGCGGTGTGAGCCGGGAGGAGATCGAGCGGGAGGTGAGCATCCTGCGGCAGGTGCTGCACCACAATGTCATCACGCT GCACGACGTCTATGAGAACCGCACCGACGTGGTGCTCATCCTTGAGCTAGTGTCTGGAGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGA GTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAACTACCTTCACACAAAGAAAATTGCTCACTTTGA TCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAAGCTGATTGACTTTGGTCTGGCTCACGAAATAGA AGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAATTGTGAACTACGAGCCCCTGGGTCTGGAGGCTGA CATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCTGGGAGACACGAAGCAGGAAACACTGGCAAATAT CACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGCCAAGGACTTTATTCGGAAGCTTCTGGTTAAAGA GACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGCCGGTGGACAACCAGCAAGCCATGGTGCGCAGGGAGTC TGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTGGAAGCTTTCCTTCAGCATCGTGTCCCTGTGCAACCACCTCAC CCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAGGAACTGTGAGAGTGACACTGAGGAGGACATCGCCAGGAGGAA >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000558069_chr15_64275953_-_2101nt ATGATGTCACAGTCATCTGGATCAGGAGATGGGAATGATGATGAGGCTACTACCTCTAAAGACGGTGGTTTTTCTTCCCCCAGTCCCTCA GCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACCAGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAAC AGCAGCAGCAGTAGCAGCAGTAACAGTAGTAACGAGAGAGAAGACTTTGATTCCACCTCTTCCTCCTCTTCCACTCCTCCTTTACAACCC AGGGATTCGGCATCCCCTTCAACCTCGTCCTTCTGCCTGGGGGTTTCAGTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAGCTGCGT TTTGAAGACACCCTGGAGTTTGTAGGGTTTGATGCGAAGATGGCTGAGGAATCCTCCTCCTCCTCCTCCTCATCTTCACCAACTGCTGCA ACATCTCAGCAGCAGCAACTTAAAAATAAGAGTATATTAATCTCTTCTGTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAATCTTCT ACCACCGTCTCTAGCTTTGCTAACAGCAAACCTGGCTCTGCTAAGAAGTTAGTGATCAAGAACTTTAAAGATAAGCCTAAATTACCAGAA AACTACACAGATGAAACCTGGCAAAAACTGAAAGAAGCAGTGGAAGCTATTCAGAATAGTACTTCAATTAAGTACAATTTAGAAGAACTC TACCAGTGGCCAGTTTGCCATCGTGAAGAAGTGCCGGGAGAAGAGCACGGGGCTTGAGTATGCAGCCAAGTTCATCAAGAAGCGGCAGAG CCGGGCGAGCCGGCGCGGTGTGAGCCGGGAGGAGATCGAGCGGGAGGTGAGCATCCTGCGGCAGGTGCTGCACCACAATGTCATCACGCT GCACGACGTCTATGAGAACCGCACCGACGTGGTGCTCATCCTTGAGCTAGTGTCTGGAGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGA GTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGATGGGGTGAACTACCTTCACACAAAGAAAATTGCTCACTTTGA TCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCCACACATCAAGCTGATTGACTTTGGTCTGGCTCACGAAATAGA AGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGCTCCAGAAATTGTGAACTACGAGCCCCTGGGTCTGGAGGCTGA CATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATCCCCTTTCCTGGGAGACACGAAGCAGGAAACACTGGCAAATAT CACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAGCGAGCTGGCCAAGGACTTTATTCGGAAGCTTCTGGTTAAAGA GACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGATCACGTCAAAAGGAGAAGGCAGAGCCCCTGAACAGCGGAAGAC AGAGCCCACCCAGCTGAAGACCAAGCACCTGAGAGAGTACACTCTCAAATGCCACTCAAGCATGCCTCCCAACAACTCCTATGTCAACTT CGAGCGTTTTGCCTGTGTGGTGGAAGACGTGGCTCGGGTCGACCTGGGATGCCGTGCCCTGGTGGAGGCCCACGATACCATCCAGGACGA TGTGGAGGCCCTGGTCTCCATCTTCAATGAGAAGGAAGCTTGGTACCGAGAGGAGAATGAGAGCGCCCGGCATGACCTGTCCCAGCTCAG GTATGAGTTCCGCAAGGTGGAGTCATTGAAGAAGCTGCTGCGAGAAGACATCCAGGCCACGGGATGTAGCCTCGGAAGCATGGCCAGGAA ACTGGACCATCTGCAAGCCCAGTTTGAGATTCTGAGGCAGGAGCTCTCCGCAGACCTGCAGTGGATTCAGGAGCTGGTGGGCAGCTTCCA GCTGGAGAGTGGGAGCTCTGAGGGCCTGGGCTCCACATTCTACCAGGACACCAGTGAATCCCTGTCAGAGCTGCTCAGCAGATCATGCAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000261891_chr15_64275953_-_3633nt AGTTCAGTTTAGAAACTGCCAGTCTTGGTATAGAACAACCTAGGCTTATCTGTTTAAGTCCCATAGGTAGTATTATTAGAGAATAACCCA GGCTTTGGGAACTGTATAACTCTGAGATCGTTTGAAATTTTCGTTTTGTTTTTCTTTTGGCTCCAACCAGGCCTCTGTTGTTAGACTAAT GGGGTTTCCCCTGCAGAGATTGGTCAGCCCTGCAGTCTATCATCCCGGAAGGTGTTAAATACACATGAAAGCCAGCCTCGGCGGGCAGAA CCTAGCCCGCCGAAAGGGCGGGCATTGCTAAAGTGTTTTCAAAAGGTCTTCCCAATCCTCTGCTTTAGACAGCTCGGACCTTAGATAGAA GAACACAACGGATCCTCCAGTGACTGACGACCCAAAGGACGGATGATGTCACAGTCATCTGGATCAGGAGATGGGAATGATGATGAGGCT ACTACCTCTAAAGACGGTGGTTTTTCTTCCCCCAGTCCCTCAGCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACC AGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAACAGCAGCAGCAGTAGCAGCAGTAACAGTAGTAACGAGAGAGAAGACTTT GATTCCACCTCTTCCTCCTCTTCCACTCCTCCTTTACAACCCAGGGATTCGGCATCCCCTTCAACCTCGTCCTTCTGCCTGGGGGTTTCA GTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAGCTGCGTTTTGAAGACACCCTGGAGTTTGTAGGGTTTGATGCGAAGATGGCTGAG GAATCCTCCTCCTCCTCCTCCTCATCTTCACCAACTGCTGCAACATCTCAGCAGCAGCAACTTAAAAATAAGAGTATATTAATCTCTTCT GTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAATCTTCTACCACCGTCTCTAGCTTTGCTAACAGCAAACCTGGCTCTGCTAAGAAG TTAGTGATCAAGAACTTTAAAGATAAGCCTAAATTACCAGAAAACTACACAGATGAAACCTGGCAAAAACTGAAAGAAGCAGTGGAAGCT ATTCAGAATAGTACTTCAATTAAGTACAATTTAGAAGAACTCTACCAGTGGCCAGTTTGCCATCGTGAAGAAGTGCCGGGAGAAGAGCAC GGGGCTTGAGTATGCAGCCAAGTTCATCAAGAAGCGGCAGAGCCGGGCGAGCCGGCGCGGTGTGAGCCGGGAGGAGATCGAGCGGGAGGT GAGCATCCTGCGGCAGGTGCTGCACCACAATGTCATCACGCTGCACGACGTCTATGAGAACCGCACCGACGTGGTGCTCATCCTTGAGCT AGTGTCTGGAGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGA TGGGGTGAACTACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCC ACACATCAAGCTGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGC TCCAGAAATTGTGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATC CCCTTTCCTGGGAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAG CGAGCTGGCCAAGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGAT CACGCCGGTGGACAACCAGCAAGCCATGGTGCGCAGGGAGTCTGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTG GAAGCTTTCCTTCAGCATCGTGTCCCTGTGCAACCACCTCACCCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAG GAACTGTGAGAGTGACACTGAGGAGGACATCGCCAGGAGGAAAGCCCTCCACCCACGGAGGAGGAGCAGCACCTCCTAACTGGCCTGACC TGCAGTGGCCGCCAGGGAGGTCTGGGCCCAGCGGGGCTCCCTTCTGTGCAGACTTTTGGACCCAGCTCAGCACCAGCACCCGGGCGTCCT GAGCACTTTGCAAGAGAGATGGGCCCAAGGAATTCAGAAGAGCTTGCAGGCAAGCCAGGAGACCCTGGGAGCTGTGGCTGTCTTCTGTGG AGGAGGCTCCAGCATTCCCAAAGCTCTTAATTCTCCATAAAATGGGCTTTCCTCTGTCTGCCATCCTCAGAGTCTGGGGTGGGAGTGTGG ACTTAGGAAAACAATATAAAGGACATCCTCATCATCACGGGGTGAAGGTCAGACTAAGGCAGCCTTCTTCACAGGCTGAGGGGGTTCAGA ACCAGCCTGGCCAAAAATTACACCAGAGAGACAGAGTCCTCCCCATTGGGAACAGGGTGATTGAGGAAAGTGAACCTTGGGTGTGAGGGA CCAATCCTGTGACCTCCCAGAACCATGGAAGCCAGGACGTCAGGCTGACCAACACCTCAGACCTTCTGAAGCAGCCCATTGCTGGCCCGC CATGTTGTAATTTTGCTCATTTTTATTAAACTTCTGGTTTACCTGATGCTTGGCTTCTTTTAGGGCTACCCCCATCTCATTTCCTTTAGC CCGTGTGCCTGTAACTCTGAGGGGGGGCACCCAGTGGGGTGCTGAGTGGGCAGAATCTCAGAAGGTCCTCCTGAACCGTCCGCGCAGGCC TGCAGTGGGCCTGCCTCCTCCTTGCTTCCCTAACAGGAAGGTGTCCAGTTCAAGAGAACCCACCCAGAGACTGGGAGTGGTGGCTCACGC CTATAATCCCTGCGCTTTGGCAGTCCGAGGCAGGGGAATTGCTTGAACTCAGGAGTTGGAGACCAGCCTGGGCAACATGGCAAAACGCAG TCTGTACAAAAAATACAAAAAATTAGCCAGGTGTAGGGGTAGGCACCTGGCATCCCAGCTACTCCAGGGGCTGAGGTGACAGCATTGCTT AAGCCCAGAAGGTCGAGGCTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGTCTGGGTGACAGAGAGAGACCATATCCAAAAAAAAAA AAAGTTGCCAGAGACGAGTATGCCCATGCTCCCTCTACCTCACTGCCACCACTCCTGCTGTTAGGAGCTGAGTGTGTCTCCCTAAAATTT CTATGTTGAAGTCTTAACCCTTGGTACCACAGAATATCACTGTATTTGGAGATGGGGTCTTTAGAAAGGCACTTAAATTAAAATGAGCTC ACTGATATGGGCCCCGATGCAATATAATTGGTGTCCTTATAAGAAGGGGAGGTTAGGACACGCAGGAAAGACCACATGAAGGCCCAGGAG TGGGAGGGGGAATAGCCATCGACAAACTAAGGGGGCCTCAGAGGAAACCAACCCTGCTGACACCTCAATCTTAGACTCTGGCCTCAAAAA >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000457488_chr15_64275953_-_2746nt AGTTCAGTTTAGAAACTGCCAGTCTTGGTATAGAACAACCTAGGCTTATCTGTTTAAGTCCCATAGGTAGTATTATTAGAGAATAACCCA GGCTTTGGGAACTGTATAACTCTGAGATCGTTTGAAATTTTCGTTTTGTTTTTCTTTTGGCTCCAACCAGGCCTCTGTTGTTAGACTAAT GGGGTTTCCCCTGCAGAGATTGGTCAGCCCTGCAGTCTATCATCCCGGAAGGTGTTAAATACACATGAAAGCCAGCCTCGGCGGGCAGAA CCTAGCCCGCCGAAAGGGCGGGCATTGCTAAAGTGTTTTCAAAAGGTCTTCCCAATCCTCTGCTTTAGACAGCTCGGACCTTAGATAGAA GAACACAACGGATCCTCCAGTGACTGACGACCCAAAGGACGGATGATGTCACAGTCATCTGGATCAGGAGATGGGAATGATGATGAGGCT ACTACCTCTAAAGACGGTGGTTTTTCTTCCCCCAGTCCCTCAGCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACC AGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAACAGCAGCAGCAGTAGCAGCAGTAACAGTAGTAACGAGAGAGAAGACTTT GATTCCACCTCTTCCTCCTCTTCCACTCCTCCTTTACAACCCAGGGATTCGGCATCCCCTTCAACCTCGTCCTTCTGCCTGGGGGTTTCA GTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAGCTGCGTTTTGAAGACACCCTGGAGTTTGTAGGGTTTGATGCGAAGATGGCTGAG GAATCCTCCTCCTCCTCCTCCTCATCTTCACCAACTGCTGCAACATCTCAGCAGCAGCAACTTAAAAATAAGAGTATATTAATCTCTTCT GTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAATCTTCTACCACCGTCTCTAGCTTTGCTAACAGCAAACCTGGCTCTGCTAAGAAG TTAGTGATCAAGAACTTTAAAGATAAGCCTAAATTACCAGAAAACTACACAGATGAAACCTGGCAAAAACTGAAAGAAGCAGTGGAAGCT ATTCAGAATAGTACTTCAATTAAGTACAATTTAGAAGAACTCTACCAGTGGCCAGTTTGCCATCGTGAAGAAGTGCCGGGAGAAGAGCAC GGGGCTTGAGTATGCAGCCAAGTTCATCAAGAAGCGGCAGAGCCGGGCGAGCCGGCGCGGTGTGAGCCGGGAGGAGATCGAGCGGGAGGT GAGCATCCTGCGGCAGGTGCTGCACCACAATGTCATCACGCTGCACGACGTCTATGAGAACCGCACCGACGTGGTGCTCATCCTTGAGCT AGTGTCTGGAGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGA TGGGGTGAACTACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCC ACACATCAAGCTGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGC TCCAGAAATTGTGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATC CCCTTTCCTGGGAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAG CGAGCTGGCCAAGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGAT CACGCCGGTGGACAACCAGCAAGCCATGGTGCGCAGGGAGTCTGTGGTCAATCTGGAGAACTTCAGGAAGCAGTATGTCCGCAGGCGGTG GAAGCTTTCCTTCAGCATCGTGTCCCTGTGCAACCACCTCACCCGCTCGCTGATGAAGAAGGTGCACCTGAGGCCGGATGAGGACCTGAG GAACTGTGAGAGTGACACTGAGGAGGACATCGCCAGGAGGAAAGCCCTCCACCCACGGAGGAGGAGCAGCACCTCCTAACTGGCCTGACC TGCAGTGGCCGCCAGGGAGGTCTGGGCCCAGCGGGGCTCCCTTCTGTGCAGACTTTTGGACCCAGCTCAGCACCAGCACCCGGGCGTCCT GAGCACTTTGCAAGAGAGATGGGCCCAAGGAATTCAGAAGAGCTTGCAGGCAAGCCAGGAGACCCTGGGAGCTGTGGCTGTCTTCTGTGG AGGAGGCTCCAGCATTCCCAAAGCTCTTAATTCTCCATAAAATGGGCTTTCCTCTGTCTGCCATCCTCAGAGTCTGGGGTGGGAGTGTGG ACTTAGGAAAACAATATAAAGGACATCCTCATCATCACGGGGTGAAGGTCAGACTAAGGCAGCCTTCTTCACAGGCTGAGGGGGTTCAGA ACCAGCCTGGCCAAAAATTACACCAGAGAGACAGAGTCCTCCCCATTGGGAACAGGGTGATTGAGGAAAGTGAACCTTGGGTGTGAGGGA CCAATCCTGTGACCTCCCAGAACCATGGAAGCCAGGACGTCAGGCTGACCAACACCTCAGACCTTCTGAAGCAGCCCATTGCTGGCCCGC >In-frame_CUL4B_ENST00000404115_chrX_119691779_-_DAPK2_ENST00000558069_chr15_64275953_-_2503nt AGTTCAGTTTAGAAACTGCCAGTCTTGGTATAGAACAACCTAGGCTTATCTGTTTAAGTCCCATAGGTAGTATTATTAGAGAATAACCCA GGCTTTGGGAACTGTATAACTCTGAGATCGTTTGAAATTTTCGTTTTGTTTTTCTTTTGGCTCCAACCAGGCCTCTGTTGTTAGACTAAT GGGGTTTCCCCTGCAGAGATTGGTCAGCCCTGCAGTCTATCATCCCGGAAGGTGTTAAATACACATGAAAGCCAGCCTCGGCGGGCAGAA CCTAGCCCGCCGAAAGGGCGGGCATTGCTAAAGTGTTTTCAAAAGGTCTTCCCAATCCTCTGCTTTAGACAGCTCGGACCTTAGATAGAA GAACACAACGGATCCTCCAGTGACTGACGACCCAAAGGACGGATGATGTCACAGTCATCTGGATCAGGAGATGGGAATGATGATGAGGCT ACTACCTCTAAAGACGGTGGTTTTTCTTCCCCCAGTCCCTCAGCTGCTGCTGCTGCTCAGGAGGTCAGATCTGCCACTGATGGTAATACC AGCACCACTCCGCCCACCTCTGCCAAGAAGAGAAAGTTAAACAGCAGCAGCAGTAGCAGCAGTAACAGTAGTAACGAGAGAGAAGACTTT GATTCCACCTCTTCCTCCTCTTCCACTCCTCCTTTACAACCCAGGGATTCGGCATCCCCTTCAACCTCGTCCTTCTGCCTGGGGGTTTCA GTGGCTGCTTCCAGCCACGTACCGATACAGAAGAAGCTGCGTTTTGAAGACACCCTGGAGTTTGTAGGGTTTGATGCGAAGATGGCTGAG GAATCCTCCTCCTCCTCCTCCTCATCTTCACCAACTGCTGCAACATCTCAGCAGCAGCAACTTAAAAATAAGAGTATATTAATCTCTTCT GTGGCTTCGGTGCATCATGCAAACGGCCTAGCCAAATCTTCTACCACCGTCTCTAGCTTTGCTAACAGCAAACCTGGCTCTGCTAAGAAG TTAGTGATCAAGAACTTTAAAGATAAGCCTAAATTACCAGAAAACTACACAGATGAAACCTGGCAAAAACTGAAAGAAGCAGTGGAAGCT ATTCAGAATAGTACTTCAATTAAGTACAATTTAGAAGAACTCTACCAGTGGCCAGTTTGCCATCGTGAAGAAGTGCCGGGAGAAGAGCAC GGGGCTTGAGTATGCAGCCAAGTTCATCAAGAAGCGGCAGAGCCGGGCGAGCCGGCGCGGTGTGAGCCGGGAGGAGATCGAGCGGGAGGT GAGCATCCTGCGGCAGGTGCTGCACCACAATGTCATCACGCTGCACGACGTCTATGAGAACCGCACCGACGTGGTGCTCATCCTTGAGCT AGTGTCTGGAGGAGAGCTCTTCGATTTCCTGGCCCAGAAGGAGTCACTGAGTGAGGAGGAGGCCACCAGCTTCATTAAGCAGATCCTGGA TGGGGTGAACTACCTTCACACAAAGAAAATTGCTCACTTTGATCTCAAGCCAGAAAACATTATGTTGTTAGACAAGAATATTCCCATTCC ACACATCAAGCTGATTGACTTTGGTCTGGCTCACGAAATAGAAGATGGAGTTGAATTTAAGAATATTTTTGGGACGCCGGAATTTGTTGC TCCAGAAATTGTGAACTACGAGCCCCTGGGTCTGGAGGCTGACATGTGGAGCATAGGCGTCATCACCTACATCCTCTTAAGTGGAGCATC CCCTTTCCTGGGAGACACGAAGCAGGAAACACTGGCAAATATCACAGCAGTGAGTTACGACTTTGATGAGGAATTCTTCAGCCAGACGAG CGAGCTGGCCAAGGACTTTATTCGGAAGCTTCTGGTTAAAGAGACCCGGAAACGGCTCACAATCCAAGAGGCTCTCAGACACCCCTGGAT CACGTCAAAAGGAGAAGGCAGAGCCCCTGAACAGCGGAAGACAGAGCCCACCCAGCTGAAGACCAAGCACCTGAGAGAGTACACTCTCAA ATGCCACTCAAGCATGCCTCCCAACAACTCCTATGTCAACTTCGAGCGTTTTGCCTGTGTGGTGGAAGACGTGGCTCGGGTCGACCTGGG ATGCCGTGCCCTGGTGGAGGCCCACGATACCATCCAGGACGATGTGGAGGCCCTGGTCTCCATCTTCAATGAGAAGGAAGCTTGGTACCG AGAGGAGAATGAGAGCGCCCGGCATGACCTGTCCCAGCTCAGGTATGAGTTCCGCAAGGTGGAGTCATTGAAGAAGCTGCTGCGAGAAGA CATCCAGGCCACGGGATGTAGCCTCGGAAGCATGGCCAGGAAACTGGACCATCTGCAAGCCCAGTTTGAGATTCTGAGGCAGGAGCTCTC CGCAGACCTGCAGTGGATTCAGGAGCTGGTGGGCAGCTTCCAGCTGGAGAGTGGGAGCTCTGAGGGCCTGGGCTCCACATTCTACCAGGA |
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FusionGenePPI for CUL4B_DAPK2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CUL4B | CAND1, RBX1, DDB1, DDB2, CUL4A, COPS5, COPS6, WDR48, DTL, COPS3, TLE1, TLE2, TLE3, WDR26, SMU1, GRWD1, WDR82, RBBP5, RFWD2, WDR5B, POC1B, SNRNP40, WDR61, WDR76, WDR5, COMMD1, UBXN7, KPNA2, KPNA4, KPNA1, KPNB1, SALL2, SIRT7, NEDD8, CDT1, CCNE1, PCNA, CUL3, ACTA2, ACTBL2, AGL, AHCY, FBF1, ALDH9A1, ALDOA, ANKRD39, ANXA7, APBB1, ASB6, B3GNT4, BLMH, C14orf166, C1QBP, RTCB, DCAF16, C9orf117, CALM1, CALM2, CALM3, CCBL2, CCDC80, CD6, CDK4, CLPX, COG4, COPS2, COPS4, COPS7A, COPS7B, COPS8, YBX3, CSN2, CSTA, CTPS1, CUL5, DAZAP1, DCD, DCUN1D1, DDX1, DDX56, DDX3X, DDX5, DHX15, DHX30, DHX9, DLGAP3, DNAJA1, DNAJC10, DOCK9, DPY19L4, EEF1A2, EEF2, EIF5A2, ELAVL1, ENO1, ENO2, ERCC8, EWSR1, FAM103A1, FAM184A, FN3KRP, FUS, GAPDH, GPS1, H2AFV, HIST1H1C, HIST2H2BE, HNRNPA1, HNRNPA2B1, HNRNPA3, HNRNPAB, HNRNPCL1, HNRNPD, HNRNPF, HNRNPH1, HNRNPH3, HNRNPK, HNRNPR, HNRNPUL1, HNRNPDL, HSD17B10, HSP90AA1, HSP90AA2P, HSP90AB1, HSPA1A, HSPA1B, HSPA1L, HSPA5, HSPA7, HSPA8, HSPA9, TOR1AIP2, IGF2BP1, ILF2, IRS4, JUP, KDM4D, KHSRP, KRT1, KRT10, KRT13, KRT14, KRT16, KRT2, KRT24, KRT5, KRT71, KRT75, KRT76, KRT85, KRT9, LARP1, LDHB, LGALS3BP, IGHV3OR15-7, LRP1B, LYZ, MCCC1, MPPED1, MYCBP2, MYEOV2, MYO18A, NAP1L1, NCL, NFKB1, NUDT1, NUDT16L1, PABPC1, PABPC4, PCBD1, PGAM5, PHIP, PLOD1, PPIA, PRDX1, PRDX3, QPCT, RBM14, RBM4, RBM3, RBMXL2, RPL11, RPL12, RPL13, RPL14, RPL15, RPL18, RPL21P19, RPL21, RPL21P16, RPL23A, RPL24, RPL26L1, RPL27, RPL27A, RPL29P30, RPL3, RPL30, RPL31, RPL35, RPL35A, RPL36AP37, HNRNPH2, RPL4, RPL6, RPL7, RPL7P32, RPL7AP9, RPL7AP27, RPL8, RPL9, RPLP0, RPLP1, RPLP2, RPS14, RPS16, RPS18, RPS2, RPS20, RPS24, RPS25, RPS26P54, RPS3, RPS4X, RPS6, RPS7, RPS8, RPSAP12, RWDD4, S100A7, SART3, SRSF1, SRSF3, SRSF4, SRSF7, SLC25A5, SNRNP70, SNRPA, SNRPB, SNRPC, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPG, SSB, SYNCRIP, TAF15, TCEAL2, TFG, TIAL1, TRIM27, TTLL7, TTN, TUBA1C, TUBA4A, TUBB, TUBB1, TUBB4B, TUFM, TXN, USP11, USP15, USP4, USP7, VPRBP, XRN2, YBX1, ZCCHC11, HIST1H2AB, HIST1H2AE, HIST1H2AG, HIST1H2AL, HIST1H2AJ, HIST1H2AK, HIST1H2AI, HIST1H2AM, UBC, CUL2, CDK2, MDM2, ERCC6, GRK5, DDA1, APP, RPTOR, DCUN1D2, DCUN1D3, DCUN1D4, DCUN1D5, BAG3, POP7, PSMA1, EIF4B, STUB1, TTC1, VASP, OIP5, TP53, NR2C2, SHFM1, HDAC1, HDAC2, SIN3A, ARID4B, SAP130, SUDS3, SAP30, RBP1, AMBRA1, DCAF6, DCAF4, DCAF17, DET1, DCAF11, DCAF8, RNF7, EGFR, CLCN1, TMEM43, DCAF4L2, CCNG1, TUBG1, NHP2L1, NXF1, NTRK1, FBXO44, DYNLT1, CCS, CDCA8, KIF15, DCAF10, BRWD3, WDR62, RBBP7, MCM2, CRBN, HUWE1, UBE2D3, HSP90B1, FKBP8, TRPC4AP, GLMN, WDTC1, CRYBA4, DCAF4L1, TMCO3, GCNT3, LINC01587, MRPS11, DCAF12L2, UHRF2, TES | DAPK2 | DAPK2, APP, FAM9B, LLGL2, RACGAP1, TUBGCP5, KLC3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CUL4B_DAPK2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CUL4B_DAPK2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CUL4B | C1845861 | MENTAL RETARDATION, X-LINKED, WITH SHORT STATURE, HYPOGONADISM, AND ABNORMAL GAIT | 1 | CTD_human;ORPHANET;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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