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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 8423

FusionGeneSummary for CREBBP_ATG10

check button Fusion gene summary
Fusion gene informationFusion gene name: CREBBP_ATG10
Fusion gene ID: 8423
HgeneTgene
Gene symbol

CREBBP

ATG10

Gene ID

1387

83734

Gene nameCREB binding proteinautophagy related 10
SynonymsCBP|KAT3A|RSTS|RSTS1APG10|APG10L|pp12616
Cytomap

16p13.3

5q14.1-q14.2

Type of geneprotein-codingprotein-coding
DescriptionCREB-binding proteinubiquitin-like-conjugating enzyme ATG10APG10 autophagy 10-likeATG10 autophagy related 10 homologautophagy-related protein 10
Modification date2018052220180523
UniProtAcc

Q92793

Q9H0Y0

Ensembl transtripts involved in fusion geneENST00000262367, ENST00000382070, 
ENST00000355178, ENST00000282185, 
ENST00000458350, ENST00000513443, 
ENST00000513634, ENST00000514253, 
Fusion gene scores* DoF score25 X 18 X 14=63004 X 3 X 4=48
# samples 344
** MAII scorelog2(34/6300*10)=-4.21174517713694
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CREBBP [Title/Abstract] AND ATG10 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Tumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCREBBP

GO:0000122

negative regulation of transcription by RNA polymerase II

21539536

HgeneCREBBP

GO:0006355

regulation of transcription, DNA-templated

12169688

HgeneCREBBP

GO:0006473

protein acetylation

15273251|24939902

HgeneCREBBP

GO:0016573

histone acetylation

11742995

HgeneCREBBP

GO:0018076

N-terminal peptidyl-lysine acetylation

12435739

HgeneCREBBP

GO:0034644

cellular response to UV

24939902

HgeneCREBBP

GO:0045893

positive regulation of transcription, DNA-templated

11742995

TgeneATG10

GO:0032446

protein modification by small protein conjugation

16963840


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVHNSCTCGA-CR-7374-01ACREBBPchr16

3900298

-ATG10chr5

81354314

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000262367ENST00000355178CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000262367ENST00000282185CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000262367ENST00000458350CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000262367ENST00000513443CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000262367ENST00000513634CREBBPchr16

3900298

-ATG10chr5

81354314

+
5CDS-intronENST00000262367ENST00000514253CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000382070ENST00000355178CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000382070ENST00000282185CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000382070ENST00000458350CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000382070ENST00000513443CREBBPchr16

3900298

-ATG10chr5

81354314

+
In-frameENST00000382070ENST00000513634CREBBPchr16

3900298

-ATG10chr5

81354314

+
5CDS-intronENST00000382070ENST00000514253CREBBPchr16

3900298

-ATG10chr5

81354314

+

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FusionProtFeatures for CREBBP_ATG10


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CREBBP

Q92793

ATG10

Q9H0Y0

Acetylates histones, giving a specific tag fortranscriptional activation. Also acetylates non-histone proteins,like NCOA3 and FOXO1. Binds specifically to phosphorylated CREBand enhances its transcriptional activity toward cAMP-responsivegenes. Acts as a coactivator of ALX1. Acts as a circadiantranscriptional coactivator which enhances the activity of thecircadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotesremoval of chromatin-bound PCNA and its degradation duringnucleotide excision repair (NER) (PubMed:24939902).{ECO:0000269|PubMed:11154691, ECO:0000269|PubMed:12738767,ECO:0000269|PubMed:12929931, ECO:0000269|PubMed:14645221,ECO:0000269|PubMed:24939902, ECO:0000269|PubMed:9707565}. E2-like enzyme involved in autophagy. Acts as an E2-likeenzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12conjugation to ATG5 is required for autophagy. Likely serves as anATG5-recognition molecule. Not involved in ATG12 conjugation toATG3 (By similarity). Plays a role in adenovirus-mediated celllysis. {ECO:0000250, ECO:0000269|PubMed:21367888}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311061_10642662443Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311199_14872662443Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311555_15622662443Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311943_19482662443Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311967_19702662443Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2312081_20852662443Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2312199_22162662443Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2312245_22482662443Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2312297_23002662443Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301061_10642662405Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301199_14872662405Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301555_15622662405Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301943_19482662405Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301967_19702662405Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2302081_20852662405Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2302199_22162662405Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2302245_22482662405Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2302297_23002662405Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311103_11752662443DomainBromo
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311323_17002662443DomainCBP/p300-type HAT
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-231587_6662662443DomainKIX
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301103_11752662405DomainBromo
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301323_17002662405DomainCBP/p300-type HAT
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-230587_6662662405DomainKIX
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311434_14362662443RegionAcetyl-CoA binding
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311446_14472662443RegionAcetyl-CoA binding
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301434_14362662405RegionAcetyl-CoA binding
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301446_14472662405RegionAcetyl-CoA binding
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311701_17442662443Zinc fingerZZ-type
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311765_18462662443Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-231347_4332662443Zinc fingerTAZ-type 1
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301701_17442662405Zinc fingerZZ-type
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301765_18462662405Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-230347_4332662405Zinc fingerTAZ-type 1


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FusionGeneSequence for CREBBP_ATG10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000355178_chr5_81354314_+_356aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000282185_chr5_81354314_+_451aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD
GYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWE
GVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000458350_chr5_81354314_+_451aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD
GYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWE
GVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000513443_chr5_81354314_+_356aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000513634_chr5_81354314_+_415aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD
GYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWE

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000355178_chr5_81354314_+_356aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000282185_chr5_81354314_+_451aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD
GYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWE
GVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000458350_chr5_81354314_+_451aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD
GYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWE
GVHECYKMRLLQGPWDTITQQEHPILGQPFFVLHPCKTNEFMTPVLKNSQKINKNVNYITSWLSIVGPVVGLNLPLSYAKATSQDERNVP

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000513443_chr5_81354314_+_356aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000513634_chr5_81354314_+_415aa
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS
ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKDCSD
GYMCKIHFQIKNGSVMSHLGASTHGQTCLPMEEAFELPLDDCEVIETAAASEVIKYEYHVLYSCSYQVPVLYFRASFLDGRPLTLKDIWE


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000355178_chr5_81354314_+_1068nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTCAAGCAG

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000282185_chr5_81354314_+_1353nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT
TTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGAATGTCAACTATATCACA
TCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACGTCTCAGGATGAACGAAATGTCCCT

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000458350_chr5_81354314_+_1353nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT
TTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGAATGTCAACTATATCACA
TCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACGTCTCAGGATGAACGAAATGTCCCT

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000513443_chr5_81354314_+_1068nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTCAAGCAG

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000513634_chr5_81354314_+_1245nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000355178_chr5_81354314_+_1068nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTCAAGCAG

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000282185_chr5_81354314_+_1353nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT
TTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGAATGTCAACTATATCACA
TCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACGTCTCAGGATGAACGAAATGTCCCT

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000458350_chr5_81354314_+_1353nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT
TTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGAATGTCAACTATATCACA
TCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACGTCTCAGGATGAACGAAATGTCCCT

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000513443_chr5_81354314_+_1068nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTCAAGCAG

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000513634_chr5_81354314_+_1245nt
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT


* Fusion transcript sequences (Full-length transcript).
>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000355178_chr5_81354314_+_2644nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTCAAGCAG
TTCTCCTGCCTCAGCCTTCCGAGTAACTGGGACTACAGGGGTTCACCACTACACCTGGCTAATTTTTTGTATTTTTAGTAGAGATAAGGT
TTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACATCAAGTAATCCATCCGCCTCAGCCTCCCAAAGTGCTGAGATTACAGGCATGA
GCCACTGTGCCTGGCCCTGAGCTTAAAATAAAAGTTAAATTAAAAAAAAAATAATGTTGATGTTTTCATTTTTGCAATCAATAGCTTAGT
TAGACTCAAATTGCAAACTGTCATTGCCTGTAGTAGGCAGTGGCATAGAACTCAATTCAGCTCTTTTAACCTGAGTTTTAAGCTGCTTTC
AGATTGCCCCACACATACATGGTTCAGGAGTCAGCCAGAGACTTGGGCTGAGTTTAAACATAGAATCTGGGGTTGTCCTCTTCTGGCTGT
CTTCTTTCTTGGGCATCTGCATCATTCTCTAGCACCTATGGTTTTTCCAGGCTCTTTCCCCCAGTTTCCTCCAGTCAGAAAGATGGCAAG
AGTTTTTGCTGCCTGCCCTCCCCCAGTCCTTGTGCCAACACCACCACCATTGCAGCTGCCTCCAGGGAAAAACTGCAAAAACCAAATCAC
TTGCTCCAGGTGTTGACTCCTCTTCAAAATCTATTTTTGTTAAATCTCCAAAGCCTCAAATAGGTTTTCTTCCTAGAATTTATATCTGTT
ATTTGTAGCAGGATTGGTCTGTAAGGCACTCAGTCTTCTACATCATGGGTCAGCAGATTACAGCCCTTGGGTTAAATCCAGCCACCTGCT

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000282185_chr5_81354314_+_4239nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT
TTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGAATGTCAACTATATCACA
TCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACGTCTCAGGATGAACGAAATGTCCCT
TAACAAGATTCTTCTATTGAGTTTAGGAATTGCGGCACGAAGAATGCCAAGAGTTTACCTGGCCAGCCCTGGCTTTAATAGGACTGATAC
CATGGAATATTTCATCTCACCAAGATGTGACATGGATTATTTTTCCCTTGGACACAAATGTCTACAGCAACTGGTGTTTGATAGGCTGAA
TGTTTAGAAGAAACACTTCAAAGGGATACATCATGGCCAGGCATGGTGGCTCACACCTGTAATCCAAGCACTTTGGGAGGCCAAGGTGGG
AGCATCACTTGATCCTGGGAGTTCGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCGGTACAAAAAAATACAAAAATTTGCCTGTTTA
TGGTGGTGTGTTCCTGTAGTCCCAGCTCCCCAGGAGGCTGAGGTGGGAGGTTGGCTTTAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAG
ACTGTGCCACTGCAGTCCAGCCTGGGTGACAGAGCCAGACACTGTCTCGGGGAAAAAAAAAAAAAAAAAAAGACACATCACTATAAATAG
CAAAAAAACAAATCTAACTTATTAATACTAGGAATACCAACATTATTAGGGCACTTGCAGGTTATTCTTTTCTAGGCCAAGTACTTCACT
TCCATTTGTCTGACATGGAGATTGAGGGAGAAATGTATTTGTGTGTTCATTTTAATGTAAGATATATAAAAATTAAATTACTGGATTTAC
CTGTCCCTGAAACTGGTGTTATAAACATGACCTATCTTAAGTGATTTTCCCACAATCAAACTCAGGAACAATAGATTATTTCTGTTTTAC
TCCAAAAGAGAGAGAGAGAGTGAGTGTGAGTGTGTGTGTGTGTGTGTGTGTATGTGTGGGTGTTTGTGTAGATAGTTGTAAAACAAAGAA
AAAACACAATATTTTACTGTGAGATAATATGTTTTACCAGCAAAGTGTGGCATAGTAATTAGAAGTTTTCTAAAAAGCTATAGGAGATAT
TTAAACATTAAAATTTCTTTTTGACCTATAGTAATAAAACAATGGTCATTTTACCCCTCTGCTTCTCAACCCCACAGCTGCTCTGCTGTA
CTCTTTGAGGGCTCTTGAGCGAGTCTTCATGTCCCTGAGACTTATTTTCCTCATCTTTAATTTGAAACTAACAAGCTACCTCATAGGGTT
GCTGTGAGAACCACATGAGATCATTAATGCATGATAAGATATTGTAAAGTATTATACGAATATTCATTAAATGCTCACCTTTCTTGTATA
TAATTGGTATTCACTAAGGCTGTAAATAAGTTTCATAGCCAGTTAAGTATTAAGATAAACCTAACCTGGAACAATTTTTTTTTTGGTTGC
TTGTTTTGTTTTTTGCTTTCATTTGCTAGGAGCTGAAACGAAGATTAAAATGTCATTGGCTTTTTAGAGAGTCTAGATTAGTGTGTCTTT
GAATGAGGGATATACTTAAAATCACCTGAGGATCGTTTACAGCTACAGATGCTGGGGCCACCTGACACAGTCTCTCTGGGGGTGATTCTG
CTCTGGAGAACCTCTGGTCTGGATATACCTTTATTGTGACATTGATTTGTATTGTTTTGCTCTACTGACAGGCCTTTTCCAATCCATACA
AGCTGAACTTGCTTCCTAATGTTTGTCTAGGCCTTACATGGATAGTAAGGAAGCTTAGGAGACATGTACACAAGGCAGCCCACTTGTAGG
AAACTGCTTCAGGTGAGGACATCATTCACCAGTGGATCACCGAGCACCGTGACAGCACCCTCAGTCCACGTCTGCAGATTAAGAGCTGAA
CTCTCACAGAGAAAGTGGAAGTAGAGAAAGGGTTAATTCAAACTGCTAGAAAAGCTAAAAGTAAATTTTAAAATGCTGAGCTGCCCATAT
TCATGCTAGGATGAGAGCCGGCTTAAATGCTTGCTGGGCATTTTGGTATTTACCACTTAGCATGTTTTCAACTTCTGTGAGGGATTTTCC
CCCCAATCTCCCTAATGTAAACACAGATTTCTCAGCAAGTCATTTCTCAAGCCATGTCATTTCTAGTGTAAAATAAATTATAATAATGTG

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000458350_chr5_81354314_+_2892nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT
TTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGAATGTCAACTATATCACA
TCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACGTCTCAGGATGAACGAAATGTCCCT
TAACAAGATTCTTCTATTGAGTTTAGGAATTGCGGCACGAAGAATGCCAAGAGTTTACCTGGCCAGCCCTGGCTTTAATAGGACTGATAC
CATGGAATATTTCATCTCACCAAGATGTGACATGGATTATTTTTCCCTTGGACACAAATGTCTACAGCAACTGGTGTTTGATAGGCTGAA
TGTTTAGAAGAAACACTTCAAAGGGATACATCATGGCCAGGCATGGTGGCTCACACCTGTAATCCAAGCACTTTGGGAGGCCAAGGTGGG
AGCATCACTTGATCCTGGGAGTTCGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCGGTACAAAAAAATACAAAAATTTGCCTGTTTA
TGGTGGTGTGTTCCTGTAGTCCCAGCTCCCCAGGAGGCTGAGGTGGGAGGTTGGCTTTAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAG
ACTGTGCCACTGCAGTCCAGCCTGGGTGACAGAGCCAGACACTGTCTCGGGGAAAAAAAAAAAAAAAAAAAGACACATCACTATAAATAG
CAAAAAAACAAATCTAACTTATTAATACTAGGAATACCAACATTATTAGGGCACTTGCAGGTTATTCTTTTCTAGGCCAAGTACTTCACT
TCCATTTGTCTGACATGGAGATTGAGGGAGAAATGTATTTGTGTGTTCATTTTAATGTAAGATATATAAAAATTAAATTACTGGATTTAC

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000513443_chr5_81354314_+_2031nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTCAAGCAG
TTCTCCTGCCTCAGCCTTCCGAGTAACTGGGACTACAGGGGTTCACCACTACACCTGGCTAATTTTTTGTATTTTTAGTAGAGATAAGGT
TTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACATCAAGTAATCCATCCGCCTCAGCCTCCCAAAGTGCTGAGATTACAGGCATGA

>In-frame_CREBBP_ENST00000262367_chr16_3900298_-_ATG10_ENST00000513634_chr5_81354314_+_2105nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT
GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT
CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC
GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG
AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA
CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC
TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT
GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT
GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGGACTGTTCTGAT
GGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCTACCCATGGACAGACATGTCTTCCC
ATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAAGTGATTAAATATGAGTATCATGTC
TTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCTTTAACTCTGAAGGACATATGGGAA
GGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAACATCCAATACTTGGGCAACCCTTT
TTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATCAATAAGTAAGAAACACCATCAAGA

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000355178_chr5_81354314_+_2038nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGATTTTGGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGC
CTTTTAAACAGTGGGAACCTTGTTCCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATC
AACCCAGGAATAGGAAATGTGAGCGCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATG
GCCAGCCTCAGTGCCATGGGCAAGAGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGG
CCCACCCCCGCTGCCTCCCAAGCACTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGA
CCTGGTATCTGCATGAATGCTAACTTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCA
CAAGGGCAGGCGCAAGTCATGAATGGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAG
GGCGCCTCGAGCAGCGTGCTGGCTGAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGA
GGCATGGCCAAGGACTGTTCTGATGGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCT
ACCCATGGACAGACATGTCTTCCCATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAA
CCTCCGCCTTCTGGGTTCAAGCAGTTCTCCTGCCTCAGCCTTCCGAGTAACTGGGACTACAGGGGTTCACCACTACACCTGGCTAATTTT
TTGTATTTTTAGTAGAGATAAGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACATCAAGTAATCCATCCGCCTCAGCCTCCC
AAAGTGCTGAGATTACAGGCATGAGCCACTGTGCCTGGCCCTGAGCTTAAAATAAAAGTTAAATTAAAAAAAAAATAATGTTGATGTTTT
CATTTTTGCAATCAATAGCTTAGTTAGACTCAAATTGCAAACTGTCATTGCCTGTAGTAGGCAGTGGCATAGAACTCAATTCAGCTCTTT
TAACCTGAGTTTTAAGCTGCTTTCAGATTGCCCCACACATACATGGTTCAGGAGTCAGCCAGAGACTTGGGCTGAGTTTAAACATAGAAT
CTGGGGTTGTCCTCTTCTGGCTGTCTTCTTTCTTGGGCATCTGCATCATTCTCTAGCACCTATGGTTTTTCCAGGCTCTTTCCCCCAGTT
TCCTCCAGTCAGAAAGATGGCAAGAGTTTTTGCTGCCTGCCCTCCCCCAGTCCTTGTGCCAACACCACCACCATTGCAGCTGCCTCCAGG
GAAAAACTGCAAAAACCAAATCACTTGCTCCAGGTGTTGACTCCTCTTCAAAATCTATTTTTGTTAAATCTCCAAAGCCTCAAATAGGTT
TTCTTCCTAGAATTTATATCTGTTATTTGTAGCAGGATTGGTCTGTAAGGCACTCAGTCTTCTACATCATGGGTCAGCAGATTACAGCCC

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000282185_chr5_81354314_+_3633nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGATTTTGGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGC
CTTTTAAACAGTGGGAACCTTGTTCCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATC
AACCCAGGAATAGGAAATGTGAGCGCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATG
GCCAGCCTCAGTGCCATGGGCAAGAGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGG
CCCACCCCCGCTGCCTCCCAAGCACTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGA
CCTGGTATCTGCATGAATGCTAACTTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCA
CAAGGGCAGGCGCAAGTCATGAATGGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAG
GGCGCCTCGAGCAGCGTGCTGGCTGAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGA
GGCATGGCCAAGGACTGTTCTGATGGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCT
ACCCATGGACAGACATGTCTTCCCATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAA
GTGATTAAATATGAGTATCATGTCTTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCT
TTAACTCTGAAGGACATATGGGAAGGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAA
CATCCAATACTTGGGCAACCCTTTTTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATC
AATAAGAATGTCAACTATATCACATCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACG
TCTCAGGATGAACGAAATGTCCCTTAACAAGATTCTTCTATTGAGTTTAGGAATTGCGGCACGAAGAATGCCAAGAGTTTACCTGGCCAG
CCCTGGCTTTAATAGGACTGATACCATGGAATATTTCATCTCACCAAGATGTGACATGGATTATTTTTCCCTTGGACACAAATGTCTACA
GCAACTGGTGTTTGATAGGCTGAATGTTTAGAAGAAACACTTCAAAGGGATACATCATGGCCAGGCATGGTGGCTCACACCTGTAATCCA
AGCACTTTGGGAGGCCAAGGTGGGAGCATCACTTGATCCTGGGAGTTCGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCGGTACAAA
AAAATACAAAAATTTGCCTGTTTATGGTGGTGTGTTCCTGTAGTCCCAGCTCCCCAGGAGGCTGAGGTGGGAGGTTGGCTTTAACCCAGG
AGGCAGAGGTTGCAGTGAGCTGAGACTGTGCCACTGCAGTCCAGCCTGGGTGACAGAGCCAGACACTGTCTCGGGGAAAAAAAAAAAAAA
AAAAAGACACATCACTATAAATAGCAAAAAAACAAATCTAACTTATTAATACTAGGAATACCAACATTATTAGGGCACTTGCAGGTTATT
CTTTTCTAGGCCAAGTACTTCACTTCCATTTGTCTGACATGGAGATTGAGGGAGAAATGTATTTGTGTGTTCATTTTAATGTAAGATATA
TAAAAATTAAATTACTGGATTTACCTGTCCCTGAAACTGGTGTTATAAACATGACCTATCTTAAGTGATTTTCCCACAATCAAACTCAGG
AACAATAGATTATTTCTGTTTTACTCCAAAAGAGAGAGAGAGAGTGAGTGTGAGTGTGTGTGTGTGTGTGTGTGTATGTGTGGGTGTTTG
TGTAGATAGTTGTAAAACAAAGAAAAAACACAATATTTTACTGTGAGATAATATGTTTTACCAGCAAAGTGTGGCATAGTAATTAGAAGT
TTTCTAAAAAGCTATAGGAGATATTTAAACATTAAAATTTCTTTTTGACCTATAGTAATAAAACAATGGTCATTTTACCCCTCTGCTTCT
CAACCCCACAGCTGCTCTGCTGTACTCTTTGAGGGCTCTTGAGCGAGTCTTCATGTCCCTGAGACTTATTTTCCTCATCTTTAATTTGAA
ACTAACAAGCTACCTCATAGGGTTGCTGTGAGAACCACATGAGATCATTAATGCATGATAAGATATTGTAAAGTATTATACGAATATTCA
TTAAATGCTCACCTTTCTTGTATATAATTGGTATTCACTAAGGCTGTAAATAAGTTTCATAGCCAGTTAAGTATTAAGATAAACCTAACC
TGGAACAATTTTTTTTTTGGTTGCTTGTTTTGTTTTTTGCTTTCATTTGCTAGGAGCTGAAACGAAGATTAAAATGTCATTGGCTTTTTA
GAGAGTCTAGATTAGTGTGTCTTTGAATGAGGGATATACTTAAAATCACCTGAGGATCGTTTACAGCTACAGATGCTGGGGCCACCTGAC
ACAGTCTCTCTGGGGGTGATTCTGCTCTGGAGAACCTCTGGTCTGGATATACCTTTATTGTGACATTGATTTGTATTGTTTTGCTCTACT
GACAGGCCTTTTCCAATCCATACAAGCTGAACTTGCTTCCTAATGTTTGTCTAGGCCTTACATGGATAGTAAGGAAGCTTAGGAGACATG
TACACAAGGCAGCCCACTTGTAGGAAACTGCTTCAGGTGAGGACATCATTCACCAGTGGATCACCGAGCACCGTGACAGCACCCTCAGTC
CACGTCTGCAGATTAAGAGCTGAACTCTCACAGAGAAAGTGGAAGTAGAGAAAGGGTTAATTCAAACTGCTAGAAAAGCTAAAAGTAAAT
TTTAAAATGCTGAGCTGCCCATATTCATGCTAGGATGAGAGCCGGCTTAAATGCTTGCTGGGCATTTTGGTATTTACCACTTAGCATGTT
TTCAACTTCTGTGAGGGATTTTCCCCCCAATCTCCCTAATGTAAACACAGATTTCTCAGCAAGTCATTTCTCAAGCCATGTCATTTCTAG

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000458350_chr5_81354314_+_2286nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGATTTTGGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGC
CTTTTAAACAGTGGGAACCTTGTTCCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATC
AACCCAGGAATAGGAAATGTGAGCGCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATG
GCCAGCCTCAGTGCCATGGGCAAGAGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGG
CCCACCCCCGCTGCCTCCCAAGCACTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGA
CCTGGTATCTGCATGAATGCTAACTTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCA
CAAGGGCAGGCGCAAGTCATGAATGGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAG
GGCGCCTCGAGCAGCGTGCTGGCTGAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGA
GGCATGGCCAAGGACTGTTCTGATGGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCT
ACCCATGGACAGACATGTCTTCCCATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAA
GTGATTAAATATGAGTATCATGTCTTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCT
TTAACTCTGAAGGACATATGGGAAGGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAA
CATCCAATACTTGGGCAACCCTTTTTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATC
AATAAGAATGTCAACTATATCACATCATGGCTGAGCATTGTAGGGCCAGTTGTTGGGCTGAATCTACCTCTGAGTTATGCCAAAGCAACG
TCTCAGGATGAACGAAATGTCCCTTAACAAGATTCTTCTATTGAGTTTAGGAATTGCGGCACGAAGAATGCCAAGAGTTTACCTGGCCAG
CCCTGGCTTTAATAGGACTGATACCATGGAATATTTCATCTCACCAAGATGTGACATGGATTATTTTTCCCTTGGACACAAATGTCTACA
GCAACTGGTGTTTGATAGGCTGAATGTTTAGAAGAAACACTTCAAAGGGATACATCATGGCCAGGCATGGTGGCTCACACCTGTAATCCA
AGCACTTTGGGAGGCCAAGGTGGGAGCATCACTTGATCCTGGGAGTTCGAGACCAGCCTGGGCAACATGGTGAAACCCTGTCGGTACAAA
AAAATACAAAAATTTGCCTGTTTATGGTGGTGTGTTCCTGTAGTCCCAGCTCCCCAGGAGGCTGAGGTGGGAGGTTGGCTTTAACCCAGG
AGGCAGAGGTTGCAGTGAGCTGAGACTGTGCCACTGCAGTCCAGCCTGGGTGACAGAGCCAGACACTGTCTCGGGGAAAAAAAAAAAAAA
AAAAAGACACATCACTATAAATAGCAAAAAAACAAATCTAACTTATTAATACTAGGAATACCAACATTATTAGGGCACTTGCAGGTTATT
CTTTTCTAGGCCAAGTACTTCACTTCCATTTGTCTGACATGGAGATTGAGGGAGAAATGTATTTGTGTGTTCATTTTAATGTAAGATATA

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000513443_chr5_81354314_+_1425nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGATTTTGGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGC
CTTTTAAACAGTGGGAACCTTGTTCCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATC
AACCCAGGAATAGGAAATGTGAGCGCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATG
GCCAGCCTCAGTGCCATGGGCAAGAGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGG
CCCACCCCCGCTGCCTCCCAAGCACTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGA
CCTGGTATCTGCATGAATGCTAACTTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCA
CAAGGGCAGGCGCAAGTCATGAATGGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAG
GGCGCCTCGAGCAGCGTGCTGGCTGAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGA
GGCATGGCCAAGGACTGTTCTGATGGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCT
ACCCATGGACAGACATGTCTTCCCATGGAGGTGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTTGCGTGATCTCAGCTCACTGCAA
CCTCCGCCTTCTGGGTTCAAGCAGTTCTCCTGCCTCAGCCTTCCGAGTAACTGGGACTACAGGGGTTCACCACTACACCTGGCTAATTTT
TTGTATTTTTAGTAGAGATAAGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACATCAAGTAATCCATCCGCCTCAGCCTCCC

>In-frame_CREBBP_ENST00000382070_chr16_3900298_-_ATG10_ENST00000513634_chr5_81354314_+_1499nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGATTTTGGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGC
CTTTTAAACAGTGGGAACCTTGTTCCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATC
AACCCAGGAATAGGAAATGTGAGCGCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATG
GCCAGCCTCAGTGCCATGGGCAAGAGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGG
CCCACCCCCGCTGCCTCCCAAGCACTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGA
CCTGGTATCTGCATGAATGCTAACTTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCA
CAAGGGCAGGCGCAAGTCATGAATGGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAG
GGCGCCTCGAGCAGCGTGCTGGCTGAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGA
GGCATGGCCAAGGACTGTTCTGATGGCTACATGTGCAAAATACACTTTCAAATTAAGAATGGGTCTGTGATGTCACATCTAGGAGCATCT
ACCCATGGACAGACATGTCTTCCCATGGAGGAGGCTTTCGAGCTACCCTTGGATGATTGTGAAGTGATTGAAACTGCAGCAGCGTCCGAA
GTGATTAAATATGAGTATCATGTCTTATATTCCTGTAGCTACCAAGTGCCTGTACTTTACTTTAGGGCAAGCTTTTTAGATGGGAGACCT
TTAACTCTGAAGGACATATGGGAAGGAGTTCATGAGTGCTATAAGATGCGACTGCTACAGGGACCATGGGACACTATTACGCAACAGGAA
CATCCAATACTTGGGCAACCCTTTTTTGTACTTCATCCCTGCAAGACGAATGAATTCATGACTCCTGTATTAAAGAATTCTCAGAAAATC


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FusionGenePPI for CREBBP_ATG10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CREBBPEGR1, HNF4A, NFE2L2, TDG, AIRE, NCOA6, BRCA1, CREB1, AR, N4BP2, CTNNB1, RELA, SS18L1, PIAS3, NPAS2, EBF1, E2F1, E2F3, KLF5, PML, SRF, TP53, KLF1, ING1, SMAD1, CSNK2A1, CUX1, ATF1, EWSR1, NR3C1, HNF1A, HOXB7, MSX1, HTT, TCF3, MGMT, KMT2A, MYOD1, ATF2, JUN, MECOM, GLI3, DDX5, PTMA, MYB, FOXO1, FOXO4, RPS6KA3, CITED1, STAT1, STAT6, MAF, PELP1, RPS6KA2, RBBP4, RBBP7, ONECUT1, SERTAD1, SREBF1, SREBF2, NFATC2, TRIP4, HIF1A, NFE2, STAT2, SMARCA4, NCOA1, ESR1, MAML1, MYBL2, KAT2B, GTF2B, CITED2, IRF3, NUP98, TRERF1, TGS1, KLF4, STAT3, NEUROG1, HIPK2, KHDRBS1, GATA1, PHOX2A, SNIP1, NFATC4, KLF13, XRCC6, FOS, POLR2A, SMARCB1, CCNC, CDK8, MED21, NKX2-1, NCOA3, PPARG, ATF4, RPA2, PPARGC1A, HIST3H3, HIST4H4, EP300, ANAPC7, ANAPC5, CDC16, ANAPC2, CDH1, CDC20, REL, DDX17, GCM1, MAP3K5, MAPK10, MKNK1, APC, PAPOLA, CPSF6, TBX21, NCOR1, NCOR2, CARM1, ESR2, YY1, MYC, PLAGL1, MIER1, HDAC1, SP1, SP3, HDAC3, VDR, DAXX, CEBPB, CEBPD, PARP1, PTMS, ATXN3, CTBP1, HIST1H3A, MTF1, SETD1A, MYBL1, NLK, SMAD3, DEK, FGFR1, RPS6KA1, CDKN1A, SND1, NCOA2, KAT6A, SRCAP, TAF6L, ETS1, ETS2, RUNX2, MAFK, TCF12, HDAC2, HOXB6, KPNA2, KPNA6, NR5A1, HMGA1, FOXO3, HIST1H4A, HES6, RUVBL1, FOSL1, FOSB, JUNB, FOXM1, HMGB1, HMGB2, POU1F1, IRF1, SMAD2, RARA, SH3GL1, BCL6, GRIP1, KLF8, NFYB, TRIM28, POT1, WDR5, IRF5, AKT1, CDC27, ATF3, ATG3, MDM2, HOXB2, HOXB3, HOXB9, HOXD12, HOXD13, HOXD10, HOXD4, HOXB4, HOXA10, HOXA9, PBX1, SMARCA2, MYH9, MSH6, MSH2, ZBTB2, ZNF639, ACTA2, CSNK2A2, TP73, PRLR, MED25, PTOV1, IFNAR2, IRF9, TBP, RPS6KA5, IRF7, KAT5, PYGO2, HBP1, TACC2, NPAT, CCNE1, ELAVL1, KDM3B, PSMC5, MDC1, LYN, HCK, SRC, ZCCHC12, RAD23A, RUNX1, CHUK, IKBKB, IKBKG, HIST2H2BE, LIG4, TLR2, EPAS1, MTDH, MEIS1, LDLR, DYRK1B, DYRK1A, CDK2, EID1, COPS2, PSME3, WRN, KLF2, UBE2D1, CREBBP, UBE2I, MAPK3, FHL1, HIST1H2BB, EID3, POU2F3, ELK1, MAPK1, TFDP1, CREM, ZEB1, CRTC1, MAML2, CENPJ, HSF1, FHL2, CDH2, PHOX2B, DDIT3, XAF1, BMI1, CCND3, TXNDC11, CCNA2, C3orf62, PPP1R13L, BRMS1, PCNA, UBE2S, TLE3, MUS81, PTTG1, MED23, SNAI1, TFAP2B, SMAD4, NR3C2, ARNTL, CLOCK, SUMO1, NFATC1, CPSF4, RFPL3, CTGF, NFYA, KIAA0430, HELZ, NISCH, SOWAHA, PCGF3, EIF4ENIF1, PAN2, JUP, HSPA8, LAMP2, TRIM25ATG10ATG12, ATG7, KRT85, MAP1B, USP11, ATG4B, ATG3, USP7, HAT1, RBBP7, ADSS


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311162_11802662443ASF1A
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301162_11802662405ASF1A
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311433_14352662443histone
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301433_14352662405histone
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311124_11702662443histone
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301124_11702662405histone
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-231227_4102662443SRCAP
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-230227_4102662405SRCAP
HgeneCREBBPchr16:3900298chr5:81354314ENST00000262367-2311460_18912662443TRERF1
HgeneCREBBPchr16:3900298chr5:81354314ENST00000382070-2301460_18912662405TRERF1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CREBBP_ATG10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CREBBP_ATG10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCREBBPC0035934Rubinstein-Taybi Syndrome3CTD_human;ORPHANET;UNIPROT
HgeneCREBBPC0033578Prostatic Neoplasms2CTD_human
HgeneCREBBPC0005586Bipolar Disorder1PSYGENET
HgeneCREBBPC0005695Bladder Neoplasm1CTD_human
HgeneCREBBPC0007137Squamous cell carcinoma1CTD_human
HgeneCREBBPC0007138Carcinoma, Transitional Cell1CTD_human
HgeneCREBBPC0010606Adenoid Cystic Carcinoma1CTD_human
HgeneCREBBPC0011573Endogenous depression1PSYGENET
HgeneCREBBPC0024301Lymphoma, Follicular1CTD_human
HgeneCREBBPC0036341Schizophrenia1PSYGENET
HgeneCREBBPC0036920Sezary Syndrome1CTD_human
HgeneCREBBPC0149925Small cell carcinoma of lung1CTD_human
HgeneCREBBPC0152013Adenocarcinoma of lung (disorder)1CTD_human
HgeneCREBBPC0279626Squamous cell carcinoma of esophagus1CTD_human
HgeneCREBBPC1862939AMYOTROPHIC LATERAL SCLEROSIS 11CTD_human