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Fusion gene ID: 7713 |
FusionGeneSummary for CNOT2_NUP107 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CNOT2_NUP107 | Fusion gene ID: 7713 | Hgene | Tgene | Gene symbol | CNOT2 | NUP107 | Gene ID | 4848 | 57122 |
| Gene name | CCR4-NOT transcription complex subunit 2 | nucleoporin 107 | |
| Synonyms | CDC36|HSPC131|NOT2|NOT2H | NPHS11|NUP84 | |
| Cytomap | 12q15 | 12q15 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CCR4-NOT transcription complex subunit 2CCR4-associated factor 2negative regulator of transcription 2 | nuclear pore complex protein Nup107nucleoporin 107kDa | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9NZN8 | P57740 | |
| Ensembl transtripts involved in fusion gene | ENST00000229195, ENST00000418359, ENST00000548230, ENST00000551483, | ENST00000229179, ENST00000378905, ENST00000539906, ENST00000401003, | |
| Fusion gene scores | * DoF score | 26 X 8 X 9=1872 | 23 X 12 X 9=2484 |
| # samples | 25 | 26 | |
| ** MAII score | log2(25/1872*10)=-2.90458043492132 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(26/2484*10)=-3.25608164519203 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CNOT2 [Title/Abstract] AND NUP107 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CNOT2 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 14707134|16712523 |
| Tgene | NUP107 | GO:0006406 | mRNA export from nucleus | 11684705 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A8-A08F-01A | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| TCGA | RV | STAD | TCGA-FP-7998-01A | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000229195 | ENST00000229179 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| 5UTR-5UTR | ENST00000229195 | ENST00000378905 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| 5UTR-5UTR | ENST00000229195 | ENST00000539906 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| 5UTR-intron | ENST00000229195 | ENST00000401003 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| 5UTR-3CDS | ENST00000418359 | ENST00000229179 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| 5UTR-5UTR | ENST00000418359 | ENST00000378905 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| 5UTR-5UTR | ENST00000418359 | ENST00000539906 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| 5UTR-intron | ENST00000418359 | ENST00000401003 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-3CDS | ENST00000548230 | ENST00000229179 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-5UTR | ENST00000548230 | ENST00000378905 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-5UTR | ENST00000548230 | ENST00000539906 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-intron | ENST00000548230 | ENST00000401003 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-3CDS | ENST00000551483 | ENST00000229179 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-5UTR | ENST00000551483 | ENST00000378905 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-5UTR | ENST00000551483 | ENST00000539906 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| intron-intron | ENST00000551483 | ENST00000401003 | CNOT2 | chr12 | 70637260 | + | NUP107 | chr12 | 69090599 | + |
| In-frame | ENST00000229195 | ENST00000229179 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 5CDS-5UTR | ENST00000229195 | ENST00000378905 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 5CDS-5UTR | ENST00000229195 | ENST00000539906 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 5CDS-intron | ENST00000229195 | ENST00000401003 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| In-frame | ENST00000418359 | ENST00000229179 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 5CDS-5UTR | ENST00000418359 | ENST00000378905 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 5CDS-5UTR | ENST00000418359 | ENST00000539906 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 5CDS-intron | ENST00000418359 | ENST00000401003 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 3UTR-3CDS | ENST00000548230 | ENST00000229179 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 3UTR-5UTR | ENST00000548230 | ENST00000378905 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 3UTR-5UTR | ENST00000548230 | ENST00000539906 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| 3UTR-intron | ENST00000548230 | ENST00000401003 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| intron-3CDS | ENST00000551483 | ENST00000229179 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| intron-5UTR | ENST00000551483 | ENST00000378905 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| intron-5UTR | ENST00000551483 | ENST00000539906 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
| intron-intron | ENST00000551483 | ENST00000401003 | CNOT2 | chr12 | 70724249 | + | NUP107 | chr12 | 69082742 | + |
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FusionProtFeatures for CNOT2_NUP107 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CNOT2 | NUP107 |
| Component of the CCR4-NOT complex which is one of themajor cellular mRNA deadenylases and is linked to various cellularprocesses including bulk mRNA degradation, miRNA-mediatedrepression, translational repression during translationalinitiation and general transcription regulation. Additionalcomplex functions may be a consequence of its influence on mRNAexpression. Required for the CCR4-NOT complex structuralintegrity. Can repress transcription and may link the CCR4-NOTcomplex to transcriptional regulation; the repressive function mayspecifically involve the N-Cor repressor complex containing HDAC3,NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES)cell identity. {ECO:0000269|PubMed:14707134,ECO:0000269|PubMed:16712523, ECO:0000269|PubMed:21299754,ECO:0000269|PubMed:22367759}. | Plays a role in the nuclear pore complex (NPC) assemblyand/or maintenance (PubMed:12552102, PubMed:15229283). Requiredfor the assembly of peripheral proteins into the NPC(PubMed:15229283, PubMed:12552102). May anchor NUP62 to the NPC(PubMed:15229283). {ECO:0000269|PubMed:12552102,ECO:0000269|PubMed:15229283}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CNOT2 | chr12:70724249 | chr12:69082742 | ENST00000229195 | + | 6 | 16 | 437_540 | 189 | 541 | Region | Note=Repressor domain |
| Hgene | >CNOT2 | chr12:70724249 | chr12:69082742 | ENST00000418359 | + | 7 | 17 | 437_540 | 189 | 541 | Region | Note=Repressor domain |
| Hgene | >CNOT2 | chr12:70724249 | chr12:69082742 | ENST00000551483 | + | 1 | 7 | 437_540 | -1385 | 192 | Region | Note=Repressor domain |
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FusionGeneSequence for CNOT2_NUP107 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CNOT2_ENST00000229195_chr12_70724249_+_NUP107_ENST00000229179_chr12_69082742_+_1113aa MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALGLPMRGMS NNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ PSRQPFTVNRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTG GKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDL VEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLV RQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTL IRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCD TWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSK WLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLE LAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFV KIPQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKYEMDFGIWK GHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFS >In-frame_CNOT2_ENST00000418359_chr12_70724249_+_NUP107_ENST00000229179_chr12_69082742_+_1113aa MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYYSQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALGLPMRGMS NNTPQLNRSLSQGTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSSSGLGSPNRSSPSIICMPKQQ PSRQPFTVNRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTG GKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDL VEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLV RQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTL IRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCD TWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSK WLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLE LAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFV KIPQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKYEMDFGIWK GHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CNOT2_ENST00000229195_chr12_70724249_+_NUP107_ENST00000229179_chr12_69082742_+_3339nt ATGGTGAGGACTGATGGACATACATTATCTGAGAAAAGAAACTACCAGGTGACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGTA GAGGGGGTCGACAGTGACTACCATGACGAAAACATGTACTACAGCCAGTCTTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCA TCACCATCTACATCAGGTCAGCTGTCTCAGTTTGGGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAGC AACAATACCCCTCAGTTAAATCGCAGCTTATCACAAGGCACTCAGTTACCGAGCCACGTCACGCCAACAACAGGGGTACCAACAATGTCA CTTCACACGCCTCCATCTCCAAGCAGGGGTATTTTGCCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGA ATTCCTAGCAGGACAAATAGCATGAGCAGTTCAGGGTTAGGTAGCCCCAACAGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCAG CCTTCTCGACAGCCTTTTACTGTGAACAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCA CGGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCT CGAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGA GGGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCA TTTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAG GATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTT GTGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCA AAAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCA TTAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTT CGACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAA TCAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTG GACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTA ATCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTG TACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGA ATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGAC ACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGAT GAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGA GTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAA TGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAG ACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACC TGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAG TTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCAT CATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCG CAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTG AAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCT ATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAA CCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAA GGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGA GAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACG ATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCT AAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATT >In-frame_CNOT2_ENST00000418359_chr12_70724249_+_NUP107_ENST00000229179_chr12_69082742_+_3339nt ATGGTGAGGACTGATGGACATACATTATCTGAGAAAAGAAACTACCAGGTGACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGTA GAGGGGGTCGACAGTGACTACCATGACGAAAACATGTACTACAGCCAGTCTTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCA TCACCATCTACATCAGGTCAGCTGTCTCAGTTTGGGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAGC AACAATACCCCTCAGTTAAATCGCAGCTTATCACAAGGCACTCAGTTACCGAGCCACGTCACGCCAACAACAGGGGTACCAACAATGTCA CTTCACACGCCTCCATCTCCAAGCAGGGGTATTTTGCCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGA ATTCCTAGCAGGACAAATAGCATGAGCAGTTCAGGGTTAGGTAGCCCCAACAGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCAG CCTTCTCGACAGCCTTTTACTGTGAACAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCA CGGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCT CGAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGA GGGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCA TTTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAG GATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTT GTGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCA AAAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCA TTAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTT CGACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAA TCAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTG GACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTA ATCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTG TACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGA ATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGAC ACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGAT GAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGA GTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAA TGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAG ACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATACC TGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAG TTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCAT CATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCG CAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTG AAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCT ATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAA CCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAA GGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGA GAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACG ATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCT AAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CNOT2_ENST00000229195_chr12_70724249_+_NUP107_ENST00000229179_chr12_69082742_+_4461nt AACACAAACACAAACACGAACACGAACACGCTCAGCGTCCCCGGGGAGGGCGGACTGAAGCCACCTCACCATTCATCGCCCCTGGACCCC GCAGTCCCCCTCGGACTCAGGGCCAGAGCCTTCTGCGAAGCAACCTAGCCCCAGGGAAACGGTAGCGGCCGCAGAAGCCCCGCTCTCTGT AACGGCCGCGGAGGAGCAGCAAGCCTCCCTGTGAGTCGGTGGGAGACAAGACGGAGCGGCGGTAAGGGCGGTAGGGAAGTGAAGCGCCTC TCTCCACCTTGTTAGAAGCGCGCTGAAAGCGGCCTGCCTACCCACCCCATCGCTGCCGTTTTGCAGTCGTCGCTCCCACCTTCCGCTGCC GCCTGGAGGGAAGCCGGAGCGACGGGGGTCACGGCGGCGGTCAGAGGGTAAAGGTCTTGCTCCCAGCAGCCTCCGCGGTGGATACGTCGC CATCTTGGATCCGCGGGACAAGAAAATTCATGCGAGGGAGACGTGGTGGGCGGTCCTTCCTGTGACACGACCCTTGAGTGACAGTTCTAT TTGATTGCCTCCGGTACTGTGAGGAAAGGACACGACTCTATGGTGAGGACTGATGGACATACATTATCTGAGAAAAGAAACTACCAGGTG ACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGTAGAGGGGGTCGACAGTGACTACCATGACGAAAACATGTACTACAGCCAGTCT TCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGCATCACCATCTACATCAGGTCAGCTGTCTCAGTTTGGGGCAAGTTTATACGGG CAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAGCAACAATACCCCTCAGTTAAATCGCAGCTTATCACAAGGCACTCAGTTACCG AGCCACGTCACGCCAACAACAGGGGTACCAACAATGTCACTTCACACGCCTCCATCTCCAAGCAGGGGTATTTTGCCTATGAATCCTAGG AATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGGAATTCCTAGCAGGACAAATAGCATGAGCAGTTCAGGGTTAGGTAGCCCCAAC AGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCAGCCTTCTCGACAGCCTTTTACTGTGAACAGGAGTGGCTTTGGAGAGATATCA TCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGCACGGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAA AATTTTGGTAATACTACACCAAGAAACCAGGTTATCCCTCGAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTA CTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGGAGGGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCC ATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGCATTTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATA ACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGAGGATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAG TCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCTTGTGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAA ATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTCAAAAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGG CTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGCATTAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAA ACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGTTCGACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAA ATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAAATCAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACT TCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATTGGACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGA GAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCTAATCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGT CAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACTGTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGG AATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAGAATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCT TTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGACACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTG GTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGATGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAA AAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAGAGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATC CTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAAATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATG ACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACAGACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTA ATAAGAGAGAAACATACAAATCTTATAGCATTTTATACCTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAA AGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGAGTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTT GAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCATCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTA AAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGCGCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTG GCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGTGAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAA GGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGCTATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTT AATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAAACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACAC AAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAAAGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTC TTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAGAGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGA AAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATACGATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATG GTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTCTAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATG CTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAATTCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGT TTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTTTTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATAT TATCGTGACACTTTCAACATGTAGGGATATCAGCGTTTCTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTA CAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAAATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTT AAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAAGCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTA AAATTAAGAAGATGACTATAACAAGAATTTTTCTAACATAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTT >In-frame_CNOT2_ENST00000418359_chr12_70724249_+_NUP107_ENST00000229179_chr12_69082742_+_4333nt AGCGTCCCCGGGGAGGGCGGACTGAAGCCACCTCACCATTCATCGCCCCTGGACCCCGCAGTCCCCCTCGGACTCAGGGCCAGAGCCTTC TGCGAAGCAACCTAGCCCCAGGGAAACGGTAGCGGCCGCAGAAGCCCCGCTCTCTGTAACGGCCGCGGAGGAGCAGCAAGCCTCCCTGTG AGTCGGTGGGAGACAAGACGGAGCGGCGTCGTCGCTCCCACCTTCCGCTGCCGCCTGGAGGGAAGCCGGAGCGACGGGGGTCACGGCGGC GGTCAGAGGGTAAAGGTCTTGCTCCCAGCAGCCTCCGCGGTGGATACGTCGCCATCTTGGATCCGCGGGACAAGAAAATTCATGCGAGGG AGACGTGGTGGGCGGTCCTTCCTGTGACACGACCCTTGAGTGACAGTTCTATTTGATTGCCTCCGGTACTGTGAGGAAAGGACACGACTC TATGGTGAGGACTGATGGACATACATTATCTGAGAAAAGAAACTACCAGGTGACAAACAGCATGTTTGGTGCTTCAAGAAAGAAGTTTGT AGAGGGGGTCGACAGTGACTACCATGACGAAAACATGTACTACAGCCAGTCTTCTATGTTTCCACATCGGTCAGAAAAAGATATGCTGGC ATCACCATCTACATCAGGTCAGCTGTCTCAGTTTGGGGCAAGTTTATACGGGCAACAAAGTGCACTAGGCCTTCCAATGAGGGGGATGAG CAACAATACCCCTCAGTTAAATCGCAGCTTATCACAAGGCACTCAGTTACCGAGCCACGTCACGCCAACAACAGGGGTACCAACAATGTC ACTTCACACGCCTCCATCTCCAAGCAGGGGTATTTTGCCTATGAATCCTAGGAATATGATGAACCACTCCCAGGTTGGTCAGGGCATTGG AATTCCTAGCAGGACAAATAGCATGAGCAGTTCAGGGTTAGGTAGCCCCAACAGAAGCTCGCCAAGCATAATATGTATGCCAAAGCAGCA GCCTTCTCGACAGCCTTTTACTGTGAACAGGAGTGGCTTTGGAGAGATATCATCCCCTGTAATCCGGGAGGCAGAGGTGACACGGACTGC ACGGAAACAGAGTGCTCAGAAAAGAGTTTTACTTCAGGCATCTCAAGATGAAAATTTTGGTAATACTACACCAAGAAACCAGGTTATCCC TCGAACTCCTAGCTCATTTCGACAGCCTTTTACCCCAACAAGCCGAAGCTTACTAAGGCAGCCAGATATTTCCTGCATTCTTGGAACAGG AGGGAAGTCGCCCCGACTTACGCAGTCTTCAGGGTTCTTTGGAAATCTCTCCATGGTTACTAATCTGGATGACAGTAACTGGGCAGCTGC ATTTTCATCACAGCGTTCCGGGCTGTTCACAAACACAGAGCCCCACAGTATAACAGAAGATGTAACTATCAGTGCTGTTATGTTACGTGA GGATGATCCTGGAGAAGCTGCATCCATGAGTATGTTTTCTGATTTCCTGCAGTCTTTTCTGAAGCACTCTTCGAGTACAGTTTTTGATCT TGTGGAAGAGTATGAAAACATCTGTGGTAGTCAGGTGAATATACTGAGTAAAATAGTGAGTCGAGCAACACCTGGACTTCAAAAATTTTC AAAAACAGCCAGTATGCTCTGGCTTCTTCAACAGGAGATGGTCACATGGAGGCTGCTGGCTTCTTTGTATAGAGACAGAATACAGTCTGC ATTAGAAGAGGAAAGTGTATTCGCAGTTACTGCTGTTAATGCCAGTGAAAAAACAGTTGTGGAAGCGTTATTTCAGAGGGATTCACTTGT TCGACAAAGTCAGCTGGTGGTAGATTGGTTAGAGAGTATTGCCAAAGATGAAATTGGAGAATTTTCTGATAATATTGAGTTTTATGCAAA ATCAGTATATTGGGAAAATACTCTGCATACCTTAAAACAACGGCAGCTGACTTCTTACGTTGGAAGTGTTCGTCCGCTTGTCACTGAATT GGACCCTGATGCTCCCATAAGACAGAAAATGCCCCTTGATGATCTGGATAGAGAAGATGAAGTTAGATTACTCAAATATCTCTTTACTCT AATCCGTGCTGGAATGACAGAAGAGGCACAACGACTCTGTAAACGCTGTGGTCAAGCATGGAGAGCTGCAACACTTGAAGGCTGGAAACT GTACCATGACCCTAATGTTAATGGAGGAACAGAATTAGAACCTGTTGAAGGGAATCCATATAGACGCATTTGGAAAATAAGTTGCTGGAG AATGGCAGAAGATGAGCTTTTTAATAGATACGAGAGAGCAATTTATGCAGCTTTAAGTGGGAATCTTAAGCAGCTGCTTCCTGTCTGTGA CACCTGGGAAGACACAGTTTGGGCCTACTTCCGGGTGATGGTGGACAGTCTGGTAGAACAGGAGATCCAGACATCAGTAGCAACTCTGGA TGAAACTGAAGAACTCCCTAGAGAATATCTGGGAGCAAACTGGACGTTAGAAAAGGTTTTTGAGGAACTTCAAGCTACTGACAAAAAGAG AGTTCTGGAAGAGAATCAAGAACATTATCATATAGTTCAAAAGTTTCTTATCCTGGGAGACATTGATGGTTTGATGGATGAGTTTAGCAA ATGGCTTTCCAAAAGCAGAAACAATCTACCTGGACACCTGCTTCGCTTTATGACTCACCTTATTTTGTTTTTCCGTACTCTGGGACTACA GACCAAGGAGGAAGTTTCTATTGAAGTTTTAAAGACATACATACAGCTTTTAATAAGAGAGAAACATACAAATCTTATAGCATTTTATAC CTGTCATTTGCCTCAAGACCTAGCTGTTGCCCAGTATGCATTATTTTTGGAAAGTGTTACAGAATTTGAACAGCGCCACCATTGCCTGGA GTTGGCTAAAGAAGCAGATTTGGATGTTGCAACAATAACAAAAACTGTAGTTGAGAATATTCGAAAGAAAGATAATGGTGAATTTAGTCA TCATGACCTGGCCCCAGCCCTAGATACTGGCACTACTGAGGAGGATCGTTTAAAAATTGATGTAATTGACTGGTTGGTATTTGACCCAGC GCAGAGGGCAGAAGCACTGAAACAAGGCAATGCAATTATGAGAAAATTCTTGGCATCAAAAAAGCACGAAGCTGCAAAAGAAGTATTTGT GAAAATTCCTCAGGATTCTATAGCAGAAATCTATAATCAGTGCGAGGAACAAGGAATGGAAAGTCCACTTCCTGCTGAAGATGATAATGC TATCCGAGAACATTTGTGCATCAGAGCTTATTTGGAAGCCCATGAAACCTTTAATGAGTGGTTTAAGCATATGAATTCAGTTCCACAAAA ACCTGCTTTGATACCTCAACCAACTTTTACTGAGAAAGTGGCTCATGAACACAAAGAAAAGAAATATGAAATGGATTTTGGTATTTGGAA AGGGCATTTGGATGCCCTAACTGCTGATGTGAAGGAGAAAATGTATAACGTCTTGTTGTTTGTTGATGGAGGGTGGATGGTGGATGTTAG AGAGGATGCCAAAGAAGACCATGAAAGAACACATCAAATGGTCTTACTGAGAAAGCTTTGTCTGCCAATGTTGTGTTTTCTGCTTCATAC GATATTGCACAGTACTGGTCAGTATCAGGAATGCCTACAGTTAGCAGATATGGTATCCTCTGAGCGCCACAAACTGTACCTGGTATTTTC TAAGGAAGAGCTAAGGAAGTTGCTGCAGAAGCTCAGAGAGTCCTCTCTAATGCTCCTAGACCAGGGACTTGACCCATTAGGGTATGAAAT TCAGTTATAGTTTAATCTTTGTAATCTCACTAATTTTCATGATAAATGAAGTTTTTAATAAAATATACTTGTTATTAGTAATTTTTTCTT TTGCATTACCATGTAAAATTTAGACATTTGAATTTTGTACTTTTCAGAATATTATCGTGACACTTTCAACATGTAGGGATATCAGCGTTT CTCTGTGTGCTTGTTAATAAAACTATATAAAAATTAAAATTTTCTGTTTTTACAAATTCCAGGGTTGTCTCTTTTTCATGTAATAAGAAA ATTAAATTTTCTGTTCTAGTTTTTTCTGTAATCATAAGCATTCTGATATTTTAAAATCATAAAGATGATGGAAAGTAGATTTATTTTTAA GCCAGGTACGTAATTTTTTATTTATCATAAAATTTAGTATTTTTGAATATTAAAATTAAGAAGATGACTATAACAAGAATTTTTCTAACA TAACATGCTATTATTATTTTAGTTATTTTGAAGACATTTCTAGTTTAACTTTCATTTAGCAAACTTCCTATCAAAATAAGAGCATATAAA |
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FusionGenePPI for CNOT2_NUP107 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CNOT2 | CNOT3, CNOT1, DDB1, HDAC3, NCOR2, NCOR1, GPS2, VCP, CNOT6L, CNOT6, NLK, RNF219, CNOT8, MMP7, CAPZA2, CNOT7, WRAP73, AURKA, TNRC6C, TNRC6A, TNRC6B, AGO2, CAPZB, XPO1, CACNA2D1, DDX11, FHL2, EIF6, POLD1, UPF1, RPL12, MRPS12, RQCD1, USP24, LARP1, CNOT10, SS18L2, CNOT11, KANSL3, TMEM165, AKIP1, DDX24, WDR26, LCOR, TNKS1BP1, CNKSR3, RC3H1, NANOS2, TOB1, RIBC1, GADD45B, GPBP1L1, TEX13A, BTRC, KLKB1, GLA, NFKB1 | NUP107 | SEH1L, NUP133, NUP85, NUP160, NUP43, NUP37, SEC13, TPR, NUP214, KPNB1, SIRT7, NUP98, WRNIP1, CUL3, CENPF, NUP153, TP53BP1, PNPT1, EIF4B, CORO1B, MYL1, C1QBP, CPSF6, VCP, PYCARD, CUL7, OBSL1, SUZ12, EED, PNKD, NTRK1, IFI16, SYNE1, APC, PRKDC, RRP1B, NALCN, CD1E, ACTBL2, HSP90AB1, XPO1, SENP1, SENP2, AHCTF1, RANGAP1, H2AFV, NUP50, RANBP2, B9D2, ACLY, RCC1, GLE1, ITPR2, KPNA4, NUP88, RAN, UBE2I, SUMO1, AAAS, RAE1, NUP155, NUP93, NUPL1, WDR1, NXF1, IPO7, NUPL2, NUP205, NUP210, NUP188, NUP62, NXT1, SEC61A1, NUP54, TMEM214, SMPD4, NDC1, KRAS, IP6K3, TMEM209, NUP35, RPUSD3, RGPD8, POM121C, FOXA3, FOXI2, FOXK2, FOXL1, FOXP3, FOXQ1, CDC5L, ZNF746, DUSP13, SPAST, UXS1, SIGLECL1, CD70, RAF1, PDHA1, TRIM25, BRCA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CNOT2_NUP107 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CNOT2_NUP107 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | NUP107 | C4225228 | NEPHROTIC SYNDROME, TYPE 11 | 1 | UNIPROT |
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