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Fusion gene ID: 7507 |
FusionGeneSummary for CLSTN1_SPA17 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CLSTN1_SPA17 | Fusion gene ID: 7507 | Hgene | Tgene | Gene symbol | CLSTN1 | SPA17 | Gene ID | 22883 | 53340 |
| Gene name | calsyntenin 1 | sperm autoantigenic protein 17 | |
| Synonyms | ALC-ALPHA|CDHR12|CST-1|CSTN1|PIK3CD|XB31alpha|alcalpha1|alcalpha2 | CT22|SP17|SP17-1 | |
| Cytomap | 1p36.22 | 11q24.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | calsyntenin-1alcadein-alphaalzheimer-related cadherin-like proteincadherin-related family member 12non-classical cadherin XB31alpha | sperm surface protein Sp17cancer/testis antigen 22sperm protein 17 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O94985 | Q15506 | |
| Ensembl transtripts involved in fusion gene | ENST00000377298, ENST00000361311, ENST00000377288, ENST00000477264, | ENST00000227135, ENST00000532692, ENST00000524614, | |
| Fusion gene scores | * DoF score | 11 X 10 X 5=550 | 2 X 2 X 2=8 |
| # samples | 15 | 2 | |
| ** MAII score | log2(15/550*10)=-1.87446911791614 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: CLSTN1 [Title/Abstract] AND SPA17 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-1550-01A | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000377298 | ENST00000227135 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| In-frame | ENST00000377298 | ENST00000532692 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| 5CDS-3UTR | ENST00000377298 | ENST00000524614 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| In-frame | ENST00000361311 | ENST00000227135 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| In-frame | ENST00000361311 | ENST00000532692 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| 5CDS-3UTR | ENST00000361311 | ENST00000524614 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| In-frame | ENST00000377288 | ENST00000227135 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| In-frame | ENST00000377288 | ENST00000532692 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| 5CDS-3UTR | ENST00000377288 | ENST00000524614 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| intron-3CDS | ENST00000477264 | ENST00000227135 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| intron-3CDS | ENST00000477264 | ENST00000532692 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
| intron-3UTR | ENST00000477264 | ENST00000524614 | CLSTN1 | chr1 | 9883701 | - | SPA17 | chr11 | 124561592 | + |
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FusionProtFeatures for CLSTN1_SPA17 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CLSTN1 | SPA17 |
| Induces KLC1 association with vesicles and functions asa cargo in axonal anterograde transport. Complex formation withAPBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to theretardation of intracellular APP maturation. In complex with APBA2and C99, a C-terminal APP fragment, abolishes C99 interaction withPSEN1 and thus APP C99 cleavage by gamma-secretase, most probablythrough stabilization of the direct interaction between APBA2 andAPP. The intracellular fragment AlcICD suppresses APBB1-dependenttransactivation stimulated by APP C-terminal intracellularfragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (Bysimilarity). {ECO:0000250, ECO:0000269|PubMed:12972431}. | Sperm surface zona pellucida binding protein. Helps tobind spermatozoa to the zona pellucida with high affinity. Mightfunction in binding zona pellucida and carbohydrates (Bysimilarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >SPA17 | chr1:9883701 | chr11:124561592 | ENST00000227135 | + | 2 | 5 | 114_143 | 75 | 152 | Domain | IQ |
| Tgene | >SPA17 | chr1:9883701 | chr11:124561592 | ENST00000532692 | + | 1 | 4 | 114_143 | 75 | 152 | Domain | IQ |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000361311 | - | 1 | 18 | 916_959 | 30 | 972 | Compositional bias | Note=Glu-rich (highly acidic) |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000377298 | - | 1 | 19 | 916_959 | 30 | 982 | Compositional bias | Note=Glu-rich (highly acidic) |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000361311 | - | 1 | 18 | 165_265 | 30 | 972 | Domain | Cadherin 2 |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000361311 | - | 1 | 18 | 38_164 | 30 | 972 | Domain | Cadherin 1 |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000377298 | - | 1 | 19 | 165_265 | 30 | 982 | Domain | Cadherin 2 |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000377298 | - | 1 | 19 | 38_164 | 30 | 982 | Domain | Cadherin 1 |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000361311 | - | 1 | 18 | 29_859 | 30 | 972 | Topological domain | Extracellular |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000361311 | - | 1 | 18 | 881_981 | 30 | 972 | Topological domain | Cytoplasmic |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000377298 | - | 1 | 19 | 29_859 | 30 | 982 | Topological domain | Extracellular |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000377298 | - | 1 | 19 | 881_981 | 30 | 982 | Topological domain | Cytoplasmic |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000361311 | - | 1 | 18 | 860_880 | 30 | 972 | Transmembrane | Helical |
| Hgene | >CLSTN1 | chr1:9883701 | chr11:124561592 | ENST00000377298 | - | 1 | 19 | 860_880 | 30 | 982 | Transmembrane | Helical |
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FusionGeneSequence for CLSTN1_SPA17 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CLSTN1_ENST00000377298_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_107aa MLRRPAPALAPAARLLLAGLLCGGGVWAARGARTTXEKXSXTRRVSDIWEGGRDISHHLRLFXGRXGKRRGCCCQNPSCLPGTHSQRGGK >In-frame_CLSTN1_ENST00000377298_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_107aa MLRRPAPALAPAARLLLAGLLCGGGVWAARGARTTXEKXSXTRRVSDIWEGGRDISHHLRLFXGRXGKRRGCCCQNPSCLPGTHSQRGGK >In-frame_CLSTN1_ENST00000361311_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_107aa MLRRPAPALAPAARLLLAGLLCGGGVWAARGARTTXEKXSXTRRVSDIWEGGRDISHHLRLFXGRXGKRRGCCCQNPSCLPGTHSQRGGK >In-frame_CLSTN1_ENST00000361311_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_107aa MLRRPAPALAPAARLLLAGLLCGGGVWAARGARTTXEKXSXTRRVSDIWEGGRDISHHLRLFXGRXGKRRGCCCQNPSCLPGTHSQRGGK >In-frame_CLSTN1_ENST00000377288_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_107aa MLRRPAPALAPAARLLLAGLLCGGGVWAARGARTTXEKXSXTRRVSDIWEGGRDISHHLRLFXGRXGKRRGCCCQNPSCLPGTHSQRGGK >In-frame_CLSTN1_ENST00000377288_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_107aa MLRRPAPALAPAARLLLAGLLCGGGVWAARGARTTXEKXSXTRRVSDIWEGGRDISHHLRLFXGRXGKRRGCCCQNPSCLPGTHSQRGGK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CLSTN1_ENST00000377298_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_322nt ATGCTGCGCCGCCCCGCTCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGA GGAGCAAGAACCACCTGAGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGA CTCTTCTGAGGAAGATAAGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAA >In-frame_CLSTN1_ENST00000377298_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_322nt ATGCTGCGCCGCCCCGCTCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGA GGAGCAAGAACCACCTGAGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGA CTCTTCTGAGGAAGATAAGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAA >In-frame_CLSTN1_ENST00000361311_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_322nt ATGCTGCGCCGCCCCGCTCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGA GGAGCAAGAACCACCTGAGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGA CTCTTCTGAGGAAGATAAGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAA >In-frame_CLSTN1_ENST00000361311_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_322nt ATGCTGCGCCGCCCCGCTCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGA GGAGCAAGAACCACCTGAGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGA CTCTTCTGAGGAAGATAAGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAA >In-frame_CLSTN1_ENST00000377288_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_322nt ATGCTGCGCCGCCCCGCTCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGA GGAGCAAGAACCACCTGAGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGA CTCTTCTGAGGAAGATAAGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAA >In-frame_CLSTN1_ENST00000377288_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_322nt ATGCTGCGCCGCCCCGCTCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGA GGAGCAAGAACCACCTGAGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGA CTCTTCTGAGGAAGATAAGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CLSTN1_ENST00000377298_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_1330nt GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG >In-frame_CLSTN1_ENST00000377298_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_4187nt GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG TTTAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGA CCCTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATC CTCTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTT AATTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGT ACAAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGA GGCTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAG CCTCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCAT GTGCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAG ACTAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGG TAATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTC CGTCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAA TACAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGA TTCTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACA AAGCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAAT ACTCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCC CTGGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAG GTTGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGC TAAACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGG ATTCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTG TCAAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAG TATATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATA CACACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGA GAACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTA ACTCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTT CATAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAAC ATCCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACAC CCAAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTT CACACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTG TTACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAA CCCATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAA TCTCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTG CAGCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAA >In-frame_CLSTN1_ENST00000361311_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_788nt GAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCGCG CGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCTAG AGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGCTC CCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTGAG AAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATAAG GAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATAGT CTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTTCT TATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTGTT >In-frame_CLSTN1_ENST00000361311_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_3645nt GAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCGCG CGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCTAG AGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGCTC CCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTGAG AAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATAAG GAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATAGT CTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTTCT TATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTGTT TAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGACC CTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATCCT CTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTTAA TTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGTAC AAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGAGG CTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAGCC TCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCATGT GCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAGAC TAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGGTA ATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTCCG TCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAATA CAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGATT CTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACAAA GCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAATAC TCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCCCT GGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAGGT TGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGCTA AACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGGAT TCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTGTC AAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAGTA TATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATACA CACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGAGA ACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTAAC TCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTTCA TAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAACAT CCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACACCC AAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTTCA CACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTGTT ACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAACC CATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAATC TCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTGCA GCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAAGA >In-frame_CLSTN1_ENST00000377288_chr1_9883701_-_SPA17_ENST00000227135_chr11_124561592_+_1330nt GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG >In-frame_CLSTN1_ENST00000377288_chr1_9883701_-_SPA17_ENST00000532692_chr11_124561592_+_4187nt GTCTCCTGGACCCCCTTTCGTGACCCCTCTCAACACCTCTACTGGGGAGACGAGGACCCCGAGGTTCTGGGGGGCGACGCGACCTGCCCG AAGTGACAAGGGTCCTGGGCCGCACTGCTCCGCCGGGGTCTGCGCTCCTCGGCGGAGCGGGTGGGAAGGATGAGTCCTCGGGGTGGAGAA GGAGGAGCGGGTCCCCGGGTACCGCTCACCCGGCCTTAGGAGCCCGGGAGCGCGCGTAGGGACGCGGAGTTGAGGCTCTCCATCTGCGGC CAGGGAAAGGGATACAGTCCCCCGGGCCCCTCCCGGCCGCTCGGAACCCACCCCAGGCGCGTCCCCGCGGGCGCGCGCTCCAGGCGGGGC CGACGGGCTCGGAGGCGCGCGCCCGCTGCCGGGTCCGCCGCGCGCGCTCCCTCCGCTCCTCTCCCCCGCCCCTCCCGGGCCCGCGCGCTC CCAGGGTCCGCCGCGCGCGCGCCTCGCGTCGCTCCCCATCCCCGCCCCTCCCGCCGCCACCCCGCCCCCGGCCGGGTACCCTCGCCGGAC CCGAGAGAGAGCGCCGCCGCCATCTTAGTTGCTGCCGCTGCCTTCAGCAAGACGCTGCTCTGAGGCGGGGAGGGCGCCGCGTCCTGAGCG CGCGGCCCAGCGTCACGGCGGCGGCGGCGGCGGCTCCTCCTTGGACCCCCGGAGCTCCCCGCGCCGCGGAGCAGCTAGCCCCAGGCCCCT AGAGCCCCGAGAGCTCCGAGAGCTCCGCTCGGCGTCCCGCGCGCCTCCCTGCCGCTCCCGCCCCGGGCTGGCGATGCTGCGCCGCCCCGC TCCCGCGCTGGCCCCGGCCGCCCGGCTGCTGCTGGCCGGGCTGCTGTGCGGCGGCGGGGTCTGGGCCGCGCGAGGAGCAAGAACCACCTG AGAAAAGTGATCCTAAACAAGAAGAGTCTCAGATATCTGGGAAGGAGGAAGAGACATCAGTCACCATCTTAGACTCTTCTGAGGAAGATA AGGAAAAAGAAGAGGTTGCTGCTGTCAAAATCCAAGCTGCCTTCCGGGGACACATAGCCAGAGAGGAGGCAAAGAAAATGAAAACAAATA GTCTTCAAAATGAGGAAAAAGAGGAAAACAAGTGAGGACACTGGTTTTACCTCCAGGAAACATGAAAAATAATCCAAATCCATCAACCTT CTTATTAATGTCATTTCTTCCTGAGGAAGGAAGATTTGATGTTGTGAAATAACATTCGTTACTGTTGTGAAAATCTGTCATGAGCATTTG TTTAATAAGCATACCATTGAAACATGCCACTTGAAGATTTCTCTGAGATCATGAGTTTGTTTACACTTGTCTCAAGCCTATCTATAGAGA CCCTTGGATTTAGAATTATAGAACTAAAGTATCTGAGATTACAGAGATCTCAGAGGTTATGTGTTCTAACTATTATCAAATGAATAAATC CTCTCTATCACATCCCCCAAAAATGTTCTTTAGCTCCTGTTTCACTCCTAGTGGTAAAGAATTTCACTGCTTTTTAAGGATAGTCTATTT AATTTTGGAATTTTTAGAAAGATAAGCTGGGACAAAAATCTGCCTCCTTCAGCCTGGCCAACATGGTGAAACCCCATGTCTACTAAAAGT ACAAAAATTGGCCAGGCGTGGTGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGA GGCTGCAGTAAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAACAAAACAAAACAAAAAAAAG CCTCTGCCTCCTTGTAAGTTTAACCCACTGGTTTTCATTTATCATACATGTATTCAATCATTTATTGAAAATGTATTGAGTACTATTCAT GTGCTGGGAATTAGTAGTGAATACTTGTTCTTACACTCATACAACTTACAATGCTTTATTGTTTTGCTCTCCAGAACCACACAGAACAAG ACTAATAACATCATATTGTAAAAAGCAAAAGCTATCATATCATGCTGCCTTCTTCAGTTAAAACTTCCCAAGTTTTTAAATATACAATGG TAATGCCTGTTTAACAAACTCAGAGGCTTTATCTCTTTTATGTTTTCAATGATTCATTCAAATCCCTAGTGCCTTAGTTTTAGAAAGTTC CGTCTCTCCTTTTTGAGGCCTCTCCACCCTTGATTGTCCAAGAAACTGAGGGTTCATGTCTTAGACCAAAGGGTGCAGTTCTCTTCCCAA TACAAAAGGTAGAAAGTGGAGTCTTACCATTTAGTTAATGCTGTTGCCTTCTACCATAATGTTGTAGCATAGTCCAGCAGACTGAGGTGA TTCTCTGGCTGGTTCCAATTCCTGCCTGCACCATAGTGGATGGCCCATGATTTAGTTCCAGGATTACATCTCTCTTGGTTTATAGTCACA AAGCCAGTGTTCCCCCAAAGCTTAAAAACAAGCCAGGATGGCTCAGTCCTGAGGAGATTCTAAAACCAGGTCTATGTTGTCACAACAAAT ACTCTCCTACAAACACTTTGATCCTTGTCCTAGGCTTAGACATGCTCTTTCTGCAAAGCAGTTTTATTTCAGGTGCCTCACTGCCCTTCC CTGGCACTGAGCCTTTATCAGGCTCTGCAACAGAGGTTCCCCCAAGTGATCGCCACTCAAACACAGTTGATTCACACCAACCCTTTCAAG GTTGTGGCTTTCATTCTCTAATGTCCACTCATACAGGCAGCCTTTCTCCTTCCAAAATCTTGCTGCCACTGTAGAGAGTTTCATGCTAGC TAAACACAAGTCTCTAATATCCCCCTTCCTCTCCTCCTTAACCCCTCTCCTCCAGGCTTACAGAGGAAAAGAAATCAGTTCTCCTCCAGG ATTCCAGCTGTTCGTCCCTCCCATTCCACTGAAAGCACCAGCTTCTAACACCTTCCCCTCTCAGACAGAGCCATCCTGCTTAGCGGATTG TCAAGGGGGGACCCAGAATTTATGCAAAGACTTAGATTCCCTGACCTGGAGAGATCAGAAGAGGAAAAAAGGGATTTTTTCCCTAGTGAG TATATAGCAGGAAAAAAAAAAAAGATGAGTTAGCTTTTTCAGTAATTCTCCTGTTATACACATAAAGTGACTAGCACTATGCATTCCATA CACACACACACACACACACAGATCTCATGGTAGTGATATTGGTAGTGAAGGAGGAAAAGGAAAAGGTGAGCAATGGATGTGATATTATGA GAACAACACATATGAATGACACTTTATTAGAACTTATCTGGTTTTCCTCTTATCTCTCTGGCTGTTCCTTCTCAATTCCCTTCACTGGTA ACTCTTCAACTCCCCAACCACTAAATGCTAAGTGCCCTTAGGCTCAGTCTTTCGACCCCATTTCTACACTCACTTGATTTCCTGCAGTTT CATAGCTTTAAAATCCAATCTTCTTAATGATCACTCCCAGACCTTTCTCTCCTCTGCCTGCGAACTTCTATATTCAACTGCCTACATAAC ATCCCCATTTGGATGTCTATAGGCATCTCAAAAGTAACATATAAAAAATGAATCCTGATATTGCCCCCAAATCTGAAACTTCCCCCACAC CCAAGTTTTTCCATTCAAAAATGGCTGCTCCATTCTTCCATTTGCTCAGGCCAAAAACCTTGGATTCATCTTTAATGCGTCACTTTCTTT CACACCCCATATACAATCTATCAGCAAAACCTGTGGGCTGTACCTATAAAATAATACTCAGAATCTGCCTACTTCTAACCACTTCCATTG TTACCGCCTTGGTCCTAGTTCCCATGATAGCCTTGTGAATTATTGCAATAACCTATATTGGCCAGTGATTATCTCACTACTACTGCACAA CCCATTCCAAAGTTAGTGGTTTAAGACAATTATATTTTCTCCTGGGTCTGTAGGTCAGTGGTAATGTAGCTAAGCTAGGCTGGACTACAA TCTCAAGGTTAGGTTCAGGTCAGCTCTAAGCTGTGGGTTTGTGGGCTGACAGGAAGGTCTGCTTCAGGCTGTGGGCCCAAGGGTCAGCTG CAGCACAGTGCCTCTGCTTCACGTGTCCTTTTCTGAGCCCCTGCTGAAAGACGTTATCCAGGACAAGCTCTTCTCATGCTGGTCACAGAA |
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FusionGenePPI for CLSTN1_SPA17 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CLSTN1 | APBA2, APP, PSEN1, TRIP12, SETDB1, SLK, MCM3AP, BAHCC1, MDM2, TM2D3, PVRIG, GINM1, CD96, CHST8, DEFA5, SCGB1D1, APBA3, PCDHA4, SLAMF1, CDCP1, LYPD5, GML, MGAT4C, ADAM33, LRRTM1, P2RX5, PCDH20, TRIM25 | SPA17 | AKAP3, AKAP7, ROPN1, MYL6B, ROPN1L, EAF1, FBXO44, PRKAR2B, SEC63, EFCAB7, WDR45B, USP33, AKAP14 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CLSTN1_SPA17 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CLSTN1_SPA17 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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