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Fusion gene ID: 6834 |
FusionGeneSummary for CEP72_CDH9 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CEP72_CDH9 | Fusion gene ID: 6834 | Hgene | Tgene | Gene symbol | CEP72 | CDH9 | Gene ID | 55722 | 1007 |
| Gene name | centrosomal protein 72 | cadherin 9 | |
| Synonyms | - | - | |
| Cytomap | 5p15.33 | 5p14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | centrosomal protein of 72 kDacentrosomal protein 72kDa | cadherin-9T1-cadherin | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9P209 | Q9ULB4 | |
| Ensembl transtripts involved in fusion gene | ENST00000264935, ENST00000444221, ENST00000514507, | ENST00000231021, | |
| Fusion gene scores | * DoF score | 5 X 4 X 5=100 | 1 X 2 X 1=2 |
| # samples | 5 | 1 | |
| ** MAII score | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/2*10)=2.32192809488736 | |
| Context | PubMed: CEP72 [Title/Abstract] AND CDH9 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A7EF-01A | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26903933 | - |
| TCGA | LD | SARC | TCGA-DX-A7EF-01A | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26902838 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000264935 | ENST00000231021 | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26903933 | - |
| 3UTR-3CDS | ENST00000444221 | ENST00000231021 | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26903933 | - |
| intron-3CDS | ENST00000514507 | ENST00000231021 | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26903933 | - |
| Frame-shift | ENST00000264935 | ENST00000231021 | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26902838 | - |
| 3UTR-3CDS | ENST00000444221 | ENST00000231021 | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26902838 | - |
| intron-3CDS | ENST00000514507 | ENST00000231021 | CEP72 | chr5 | 639339 | + | CDH9 | chr5 | 26902838 | - |
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FusionProtFeatures for CEP72_CDH9 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CEP72 | CDH9 |
| Involved in the recruitment of key centrosomal proteinsto the centrosome. Provides centrosomal microtubule-nucleationactivity on the gamma-tubulin ring complexes (gamma-TuRCs) and hascritical roles in forming a focused bipolar spindle, which isneeded for proper tension generation between sister chromatids.Required for localization of KIZ, AKAP9 and gamma-tubulin ringcomplexes (gamma-TuRCs) (PubMed:19536135). Involved in centrioleduplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63centrosomal localization and promotes the centrosomal localizationof CDK2 (PubMed:26297806). {ECO:0000269|PubMed:19536135,ECO:0000269|PubMed:26297806}. | Cadherins are calcium-dependent cell adhesion proteins.They preferentially interact with themselves in a homophilicmanner in connecting cells; cadherins may thus contribute to thesorting of heterogeneous cell types. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000444221 | + | 7 | 11 | 476_620 | 387 | 306 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000264935 | + | 8 | 12 | 111_150 | 447 | 648 | Domain | Note=LRRCT |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000444221 | + | 7 | 11 | 111_150 | 387 | 306 | Domain | Note=LRRCT |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000264935 | + | 8 | 12 | 29_50 | 447 | 648 | Repeat | Note=LRR 1 |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000264935 | + | 8 | 12 | 55_76 | 447 | 648 | Repeat | Note=LRR 2 |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000264935 | + | 8 | 12 | 77_98 | 447 | 648 | Repeat | Note=LRR 3 |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000444221 | + | 7 | 11 | 29_50 | 387 | 306 | Repeat | Note=LRR 1 |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000444221 | + | 7 | 11 | 55_76 | 387 | 306 | Repeat | Note=LRR 2 |
| Hgene | CEP72 | chr5:639339 | chr5:26903933 | ENST00000444221 | + | 7 | 11 | 77_98 | 387 | 306 | Repeat | Note=LRR 3 |
| Tgene | >CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 269_383 | 270 | 790 | Domain | Cadherin 3 |
| Tgene | >CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 384_486 | 270 | 790 | Domain | Cadherin 4 |
| Tgene | >CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 487_608 | 270 | 790 | Domain | Cadherin 5 |
| Tgene | >CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 637_789 | 270 | 790 | Topological domain | Cytoplasmic |
| Tgene | >CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 616_636 | 270 | 790 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CEP72 | chr5:639339 | chr5:26903933 | ENST00000264935 | + | 8 | 12 | 476_620 | 447 | 648 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 160_268 | 270 | 790 | Domain | Cadherin 2 |
| Tgene | CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 54_159 | 270 | 790 | Domain | Cadherin 1 |
| Tgene | CDH9 | chr5:639339 | chr5:26903933 | ENST00000231021 | - | 4 | 12 | 54_615 | 270 | 790 | Topological domain | Extracellular |
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FusionGeneSequence for CEP72_CDH9 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CEP72_ENST00000264935_chr5_639339_+_CDH9_ENST00000231021_chr5_26903933_-_967aa MARAGPRLVLSEEAVRAKSGLGPHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISS LAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRASERKASRLHFASEDSLDSKESVPASLKEGRPHHPRAKCT EALAKQSLVMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQESRHLLSPQLVQYQCGDSGKQGRETRRSSCRGCCLEKMPW SQLCGELPPLYGAEPEASRAPRPHTYFTPHPDSMDTEDSASSQKLDLSGEMVPGPLPAPGKCRKRRMPVGRFQTFSDQEGLGCPERTHGS SVPKESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLETLLDLVDRSWGGCRSLHSNEAFLGTY QFNSPESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDFENQMLYTLRVDASNTHPDPRFLHLGP FKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVKEGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPW HNITVTATEINNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNK DNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQSCTAEALILSAGLSTGALVAILLCVLILLILVVLF AALKRQRKKEPLIISKDDVRDNIVTYNDEGGGEEDTQAFDIGTLRNPEAREDSKLRRDVMPETIFQIRRTVPLWENIDVQDFIHRRLKEN |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CEP72_ENST00000264935_chr5_639339_+_CDH9_ENST00000231021_chr5_26903933_-_2901nt ATGGCGCGGGCTGGCCCTCGGCTGGTGCTGAGCGAGGAGGCGGTTCGGGCGAAGAGCGGCTTAGGGCCTCACCGCGACCTGGCTGAGCTT CAGTCATTGTCTATTCCTGGAACTTACCAAGAGAAGATCACCCACCTGGGACATTCTCTGATGAGTTTAACAGGTCTGAAATCTTTGGAT CTCTCGCGCAACTCCTTGGTTAGTCTGGAGGGCATTCAGTACCTGACTGCATTGGAGAGTCTCAATCTCTACTACAACTGCATCTCCTCG TTGGCAGAAGTGTTTCGGCTCCACGCCTTAACCGAGCTCGTGGATGTGGACTTCCGGCTGAACCCCGTGGTGAAGGTTGAGCCTGACTAC CGCCTTTTTGTTGTGCACCTGCTCCCCAAGCTCCAGCAGCTGGACGATCGCCCCGTGAGAGCAAGCGAGCGGAAGGCTTCCCGACTGCAT TTTGCATCAGAGGACTCACTCGACTCCAAAGAGAGCGTCCCAGCTTCTTTGAAAGAGGGCAGACCACACCACCCCAGAGCCAAGTGCACC GAGGCCTTGGCCAAGCAGAGCCTGGTCATGGATGCGGATGACGAGGCAGTCCTGAACCTCATTGCAGAGTGCGAGTGGGACCTCGGCAGG CCTCCCGGGAGCACGAGCTTCAGCCAGAAGGGGCGTGAGGCCGACTCTCGTGGTTCCCAAGAATCCAGACATCTGTTGAGCCCGCAGTTG GTACAGTACCAGTGTGGGGACTCTGGGAAGCAGGGCCGTGAGACGAGGAGGAGCAGCTGCAGAGGGTGCTGTCTGGAGAAGATGCCTTGG AGCCAGCTCTGTGGAGAGCTTCCGCCACTGTACGGAGCGGAGCCAGAGGCCTCCCGTGCCCCCAGGCCACACACGTACTTCACCCCACAC CCAGACTCCATGGATACCGAGGACTCGGCCTCTTCTCAGAAGTTGGATTTGTCAGGAGAAATGGTGCCTGGTCCCCTGCCAGCCCCCGGA AAGTGCAGGAAGCGAAGAATGCCTGTTGGAAGATTCCAGACGTTTTCGGACCAGGAGGGTTTGGGCTGCCCGGAGAGAACTCATGGGTCC TCCGTGCCCAAGGAGAGCCTGAGCAGACAGGACAGCTCAGAAAGCAGGAACGGGAGGACCTTGTCTCAGCCTGAGGCCTCGGAGACTGAG GAGCAGAGGTCTCGGGGTGTGACCGACACCAGAGAGCCGTCTCCCGGGTCACACTCGGCTCTACCCGGGAAGAAGACGGCCCTGCAGGCG GCGCTCCTGGAGACGCTCTTGGACCTGGTGGACAGGAGCTGGGGCGGCTGCAGGTCCCTGCACAGCAACGAGGCATTCCTTGGTACGTAT CAATTTAATTCTCCTGAGTCTGTACCTCTTGGAACTCATCTTGGAAGGATAAAAGCCAATGACCCTGACGTGGGGGAAAATGCAGAAATG GAGTATAGCATTGCTGAAGGAGATGGTGCAGACATGTTCGATGTCATCACTGACAAGGATACACAGGAAGGGATTATAACTGTCAAACAG AATTTAGATTTTGAAAATCAAATGCTCTATACTTTAAGAGTGGATGCAAGTAACACTCACCCTGATCCACGATTCTTACACCTGGGACCT TTCAAAGATACAGCTGTGGTCAAAATATCTGTGGAAGATATAGATGAGCCTCCTGTGTTCACTAAAGTCTCTTACTTGATAGAAGTAGAT GAAGATGTAAAGGAGGGCAGTATCATTGGACAGGTTACAGCATACGATCCAGATGCCAGGAACAATTTAATAAAGTACTCTGTTGATCGG CATACTGATATGGACCGTATTTTTGGTATTCACTCAGAAAATGGTTCTATTTTCACTTTGAAAGCCCTTGACCGGGAATCATCTCCTTGG CATAACATCACTGTTACAGCCACAGAAATAAATAACCCAAAACAAAGTAGCCACATCCCTGTCTTCATCAGAATTCTAGATATAAATGAC CATGCTCCGGAATTTGCCATGTATTATGAAACATTTGTTTGTGAAAATGCAAAACCTGGGCAGTTGATTCAGACTGTCAGTGTCATGGAT AAGGATGACCCTCCCCGAGGTCACAAATTCTTTTTTGAACCAGTGCCAGAATTTACTCTCAATCCGAATTTCACCATTGTAGATAATAAA GATAATACAGCAGGAATCATGACTCGGAAAGATGGCTACAGTCGCAACAAAATGAGCACCTACTTATTGCCGATTTTAATCTTTGACAAC GATTATCCAATTCAAAGCAGCACTGGTACACTCACTATCCGTGTGTGTGCCTGCGATAATCAAGGAAACATGCAATCCTGCACCGCAGAA GCCCTGATCCTTTCAGCCGGCCTGAGCACGGGAGCTCTCGTTGCGATTCTACTCTGTGTCCTCATACTGCTTATTTTAGTCGTGTTGTTT GCTGCATTGAAGAGGCAAAGAAAAAAGGAACCTCTGATAATTTCAAAAGACGATGTCCGGGACAACATTGTGACCTACAACGATGAAGGC GGCGGGGAAGAAGATACCCAAGCTTTTGACATTGGCACATTAAGGAATCCAGAGGCAAGAGAAGACAGTAAACTTAGACGGGATGTAATG CCTGAAACTATTTTTCAGATAAGGAGGACTGTGCCTCTGTGGGAAAATATTGATGTACAAGATTTTATCCATCGAAGATTAAAAGAAAAC GACGCAGACCCAAGTGCACCTCCATATGATTCGCTGGCAACGTATGCCTATGAAGGGAATGATTCCATAGCAGATTCGCTCAGTTCTTTG GAATCTCTCACAGCTGATTGTAACCAAGATTATGATTACCTCAGTGACTGGGGGCCTCGTTTCAAAAAACTTGCCGATATGTATGGGGGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CEP72_ENST00000264935_chr5_639339_+_CDH9_ENST00000231021_chr5_26903933_-_3527nt GGCTCTCGGTTCTGCCGACGCAGGTCCCGCCCCTCTCGTAGCCTCGCCCCGCCCGCCGCGCAGGCGCCGTCCGAGGGCTCCGTTTGAAAC ATGGCGCGGGCTGGCCCTCGGCTGGTGCTGAGCGAGGAGGCGGTTCGGGCGAAGAGCGGCTTAGGGCCTCACCGCGACCTGGCTGAGCTT CAGTCATTGTCTATTCCTGGAACTTACCAAGAGAAGATCACCCACCTGGGACATTCTCTGATGAGTTTAACAGGTCTGAAATCTTTGGAT CTCTCGCGCAACTCCTTGGTTAGTCTGGAGGGCATTCAGTACCTGACTGCATTGGAGAGTCTCAATCTCTACTACAACTGCATCTCCTCG TTGGCAGAAGTGTTTCGGCTCCACGCCTTAACCGAGCTCGTGGATGTGGACTTCCGGCTGAACCCCGTGGTGAAGGTTGAGCCTGACTAC CGCCTTTTTGTTGTGCACCTGCTCCCCAAGCTCCAGCAGCTGGACGATCGCCCCGTGAGAGCAAGCGAGCGGAAGGCTTCCCGACTGCAT TTTGCATCAGAGGACTCACTCGACTCCAAAGAGAGCGTCCCAGCTTCTTTGAAAGAGGGCAGACCACACCACCCCAGAGCCAAGTGCACC GAGGCCTTGGCCAAGCAGAGCCTGGTCATGGATGCGGATGACGAGGCAGTCCTGAACCTCATTGCAGAGTGCGAGTGGGACCTCGGCAGG CCTCCCGGGAGCACGAGCTTCAGCCAGAAGGGGCGTGAGGCCGACTCTCGTGGTTCCCAAGAATCCAGACATCTGTTGAGCCCGCAGTTG GTACAGTACCAGTGTGGGGACTCTGGGAAGCAGGGCCGTGAGACGAGGAGGAGCAGCTGCAGAGGGTGCTGTCTGGAGAAGATGCCTTGG AGCCAGCTCTGTGGAGAGCTTCCGCCACTGTACGGAGCGGAGCCAGAGGCCTCCCGTGCCCCCAGGCCACACACGTACTTCACCCCACAC CCAGACTCCATGGATACCGAGGACTCGGCCTCTTCTCAGAAGTTGGATTTGTCAGGAGAAATGGTGCCTGGTCCCCTGCCAGCCCCCGGA AAGTGCAGGAAGCGAAGAATGCCTGTTGGAAGATTCCAGACGTTTTCGGACCAGGAGGGTTTGGGCTGCCCGGAGAGAACTCATGGGTCC TCCGTGCCCAAGGAGAGCCTGAGCAGACAGGACAGCTCAGAAAGCAGGAACGGGAGGACCTTGTCTCAGCCTGAGGCCTCGGAGACTGAG GAGCAGAGGTCTCGGGGTGTGACCGACACCAGAGAGCCGTCTCCCGGGTCACACTCGGCTCTACCCGGGAAGAAGACGGCCCTGCAGGCG GCGCTCCTGGAGACGCTCTTGGACCTGGTGGACAGGAGCTGGGGCGGCTGCAGGTCCCTGCACAGCAACGAGGCATTCCTTGGTACGTAT CAATTTAATTCTCCTGAGTCTGTACCTCTTGGAACTCATCTTGGAAGGATAAAAGCCAATGACCCTGACGTGGGGGAAAATGCAGAAATG GAGTATAGCATTGCTGAAGGAGATGGTGCAGACATGTTCGATGTCATCACTGACAAGGATACACAGGAAGGGATTATAACTGTCAAACAG AATTTAGATTTTGAAAATCAAATGCTCTATACTTTAAGAGTGGATGCAAGTAACACTCACCCTGATCCACGATTCTTACACCTGGGACCT TTCAAAGATACAGCTGTGGTCAAAATATCTGTGGAAGATATAGATGAGCCTCCTGTGTTCACTAAAGTCTCTTACTTGATAGAAGTAGAT GAAGATGTAAAGGAGGGCAGTATCATTGGACAGGTTACAGCATACGATCCAGATGCCAGGAACAATTTAATAAAGTACTCTGTTGATCGG CATACTGATATGGACCGTATTTTTGGTATTCACTCAGAAAATGGTTCTATTTTCACTTTGAAAGCCCTTGACCGGGAATCATCTCCTTGG CATAACATCACTGTTACAGCCACAGAAATAAATAACCCAAAACAAAGTAGCCACATCCCTGTCTTCATCAGAATTCTAGATATAAATGAC CATGCTCCGGAATTTGCCATGTATTATGAAACATTTGTTTGTGAAAATGCAAAACCTGGGCAGTTGATTCAGACTGTCAGTGTCATGGAT AAGGATGACCCTCCCCGAGGTCACAAATTCTTTTTTGAACCAGTGCCAGAATTTACTCTCAATCCGAATTTCACCATTGTAGATAATAAA GATAATACAGCAGGAATCATGACTCGGAAAGATGGCTACAGTCGCAACAAAATGAGCACCTACTTATTGCCGATTTTAATCTTTGACAAC GATTATCCAATTCAAAGCAGCACTGGTACACTCACTATCCGTGTGTGTGCCTGCGATAATCAAGGAAACATGCAATCCTGCACCGCAGAA GCCCTGATCCTTTCAGCCGGCCTGAGCACGGGAGCTCTCGTTGCGATTCTACTCTGTGTCCTCATACTGCTTATTTTAGTCGTGTTGTTT GCTGCATTGAAGAGGCAAAGAAAAAAGGAACCTCTGATAATTTCAAAAGACGATGTCCGGGACAACATTGTGACCTACAACGATGAAGGC GGCGGGGAAGAAGATACCCAAGCTTTTGACATTGGCACATTAAGGAATCCAGAGGCAAGAGAAGACAGTAAACTTAGACGGGATGTAATG CCTGAAACTATTTTTCAGATAAGGAGGACTGTGCCTCTGTGGGAAAATATTGATGTACAAGATTTTATCCATCGAAGATTAAAAGAAAAC GACGCAGACCCAAGTGCACCTCCATATGATTCGCTGGCAACGTATGCCTATGAAGGGAATGATTCCATAGCAGATTCGCTCAGTTCTTTG GAATCTCTCACAGCTGATTGTAACCAAGATTATGATTACCTCAGTGACTGGGGGCCTCGTTTCAAAAAACTTGCCGATATGTATGGGGGT GATGATAGTGACCGAGACTAAGAGGATTGTTTGACTTAATCAATATTAGTGGAAGTACTGTCTATGTTATTAGATTGAGTGGCCTGCATT CTCTTCCTGGGAGGAAATCTTTCAAAAATTGAAGTTACAAACAATACGTAGATGTTGTCAAGTAGGGATTTGCTTAATCAGTAAGTCTTT GTGAATGAATACGAATGATACAGATTTTTAAAAAAGTAATAACCAGTTCACCCTCTTTGCCTAACAATCTCGGAAGGAAAATATATCACA TCAATAATCAATAAAAATAAGTAAAAGGCTTTTTGTGCCTTTTCTTAGGTATAATAATTTATAAATGTTTTCTTAACTGACTTTCAGTCA CCTTTACAATTAAACTAAATATTGTGCAACCGCTTTGTAAATTAATATGAAGAAGATATATCCCTAATGAAATAGGAATGACTATTACTG CCATATTTATTTAGTTGAAGAATGTCTTTGTGTTAATTCATTCATATTTTTATAAATGTATATTTATATTTTTGTATTTTTATGAAATAA |
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FusionGenePPI for CEP72_CDH9 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CEP72 | KIAA0408, ZBTB16, IGHM, LNX1, ZNF417, MCM10, SPATA2, PCM1, ATXN7, LATS2, SAV1, HSPA1A, DDB1, TRAP1, GPR112, PCLO, RAVER1, SLC4A10, TBC1D4, TUBA1C, PIN4, PSMA1, SRSF2, NME7, FAM90A1, STAMBPL1, SPATA24, CATIP, RASSF7, SEPT6, KIAA0753, CCDC14, MED4, CEP290, OFD1, CEP162, CEP120, SPICE1, CEP128, CEP135, CEP63, CEP89, ODF2, POC5, LCA5, CSNK1E, DSP, HSPA5, PCNT, PPP2CB, PRKAR2B, DYNLL1, FGFR1OP, MAPRE1, HAUS2, NEDD1, KIF7, PPP2R3C, GAN, TPTE2, GGA1, RGS3, AHCYL2, ZKSCAN1, HOMER1, AHCYL1, CTU2, CHAF1B, TRIM25, BRCA1 | CDH9 | CTNNB1, ELAVL1, MEOX2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CEP72_CDH9 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CEP72_CDH9 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CDH9 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Tgene | CDH9 | C0004352 | Autistic Disorder | 1 | CTD_human |
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