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Fusion gene ID: 6679 |
FusionGeneSummary for CDYL2_DYNLRB2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDYL2_DYNLRB2 | Fusion gene ID: 6679 | Hgene | Tgene | Gene symbol | CDYL2 | DYNLRB2 | Gene ID | 124359 | 83657 |
| Gene name | chromodomain Y like 2 | dynein light chain roadblock-type 2 | |
| Synonyms | PCCP1 | DNCL2B|DNLC2B|ROBLD2 | |
| Cytomap | 16q23.2 | 16q23.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | chromodomain Y-like protein 2CDY-like 2chromodomain protein, Y-like 2prostate cancer candidate protein 1, PCCP1 | dynein light chain roadblock-type 2bithoraxoid-like proteindynein light chain 2B, cytoplasmicdynein, cytoplasmic, light polypeptide 2Broadblock domain-containing protein 2testicular tissue protein Li 53 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8N8U2 | Q8TF09 | |
| Ensembl transtripts involved in fusion gene | ENST00000570137, ENST00000562812, ENST00000566173, ENST00000563890, ENST00000562753, | ENST00000562982, ENST00000305904, ENST00000568035, ENST00000570222, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 4 X 3 X 4=48 |
| # samples | 5 | 4 | |
| ** MAII score | log2(5/32*10)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CDYL2 [Title/Abstract] AND DYNLRB2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-HC-8264-01B | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000570137 | ENST00000562982 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000570137 | ENST00000305904 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000570137 | ENST00000568035 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| 5CDS-intron | ENST00000570137 | ENST00000570222 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000562812 | ENST00000562982 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000562812 | ENST00000305904 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000562812 | ENST00000568035 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| 5CDS-intron | ENST00000562812 | ENST00000570222 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000566173 | ENST00000562982 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000566173 | ENST00000305904 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000566173 | ENST00000568035 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| 5CDS-intron | ENST00000566173 | ENST00000570222 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000563890 | ENST00000562982 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000563890 | ENST00000305904 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| In-frame | ENST00000563890 | ENST00000568035 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| 5CDS-intron | ENST00000563890 | ENST00000570222 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| intron-3CDS | ENST00000562753 | ENST00000562982 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| intron-3CDS | ENST00000562753 | ENST00000305904 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| intron-3CDS | ENST00000562753 | ENST00000568035 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
| intron-intron | ENST00000562753 | ENST00000570222 | CDYL2 | chr16 | 80838047 | - | DYNLRB2 | chr16 | 80577173 | + |
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FusionProtFeatures for CDYL2_DYNLRB2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDYL2 | DYNLRB2 |
| Acts as one of several non-catalytic accessorycomponents of the cytoplasmic dynein 1 complex that are thought tobe involved in linking dynein to cargos and to adapter proteinsthat regulate dynein function. Cytoplasmic dynein 1 acts as amotor for the intracellular retrograde motility of vesicles andorganelles along microtubules. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CDYL2 | chr16:80838047 | chr16:80577173 | ENST00000570137 | - | 1 | 7 | 7_67 | 8 | 507 | Domain | Chromo |
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FusionGeneSequence for CDYL2_DYNLRB2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_48aa >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_48aa >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_48aa >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_104aa MASGDLYEAEVEETLKRIQSHKGVIGTMVVNAEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPD >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_48aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_144nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_144nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_144nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_312nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_144nt ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_551nt CTGTCATTCTGCAAAAACACAGTTTACTCAACACACCACACACACTCGCACACACACGCGCGCACACACACGCGCACACCGGACCCCGCG CGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGCATGGCTTCTGGGGACCTTTACGAG GCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTAAATGCAGAAGGTATTCCCATCCGA ACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCCAAAAGCACAGTTCGTGATATTGAT CCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGATAAGGAATATCTTCTGATCGTCATT CAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTTGGCTCTCTCATGAGTATTAAAATT >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_554nt CTGTCATTCTGCAAAAACACAGTTTACTCAACACACCACACACACTCGCACACACACGCGCGCACACACACGCGCACACCGGACCCCGCG CGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGCATGGCTTCTGGGGACCTTTACGAG GCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTAAATGCAGAAGGTATTCCCATCCGA ACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCCAAAAGCACAGTTCGTGATATTGAT CCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGATAAGGAATATCTTCTGATCGTCATT CAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTTGGCTCTCTCATGAGTATTAAAATT >In-frame_CDYL2_ENST00000570137_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_502nt CTGTCATTCTGCAAAAACACAGTTTACTCAACACACCACACACACTCGCACACACACGCGCGCACACACACGCGCACACCGGACCCCGCG CGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGCATGGCTTCTGGGGACCTTTACGAG GCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTAAATGCAGAAGATAAGGAATATCTT CTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTTGGCTCTCTCATG AGTATTAAAATTCTATTTCAATCTAACTGACCCTTCAAACATTCTTTTCTATTTCTATATCTAAACTGTTCTGCATGTCTCATTTAGTCC >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_485nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT AAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTT >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_488nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT AAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTT >In-frame_CDYL2_ENST00000562812_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_436nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGATAAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGG TTGGAAACACTTGGCTCTCTCATGAGTATTAAAATTCTATTTCAATCTAACTGACCCTTCAAACATTCTTTTCTATTTCTATATCTAAAC >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_485nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT AAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTT >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_488nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT AAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTT >In-frame_CDYL2_ENST00000566173_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_436nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGATAAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGG TTGGAAACACTTGGCTCTCTCATGAGTATTAAAATTCTATTTCAATCTAACTGACCCTTCAAACATTCTTTTCTATTTCTATATCTAAAC >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000562982_chr16_80577173_+_485nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT AAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTT >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000305904_chr16_80577173_+_488nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGGTATTCCCATCCGAACAACCTTGGACAACTCAACAACTGTTCAATATGCAGGCCTTCTTCATCACCTGACAATGAAAGCC AAAAGCACAGTTCGTGATATTGATCCTCAGAACGACCTGACTTTTCTTAGGATCAGATCAAAGAAACATGAAATCATGGTAGCTCCAGAT AAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGGTTGGAAACACTT >In-frame_CDYL2_ENST00000563890_chr16_80838047_-_DYNLRB2_ENST00000568035_chr16_80577173_+_436nt CACACGCGCACACCGGACCCCGCGCGCACACGCACGGAGGGCGCGAGCGAGCAGACGCGCACACCGGCGAGCCAAGTTCCGCAGCCTGGC ATGGCTTCTGGGGACCTTTACGAGGCAGAGGTGGAGGAAACCTTAAAGAGGATCCAGAGTCATAAAGGGGTTATTGGAACTATGGTTGTA AATGCAGAAGATAAGGAATATCTTCTGATCGTCATTCAGAATCCATGTGAATAGACCTGCGATGGCCAAGGCTGTTTAAGCGACACTGGG TTGGAAACACTTGGCTCTCTCATGAGTATTAAAATTCTATTTCAATCTAACTGACCCTTCAAACATTCTTTTCTATTTCTATATCTAAAC |
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FusionGenePPI for CDYL2_DYNLRB2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CDYL2 | HINFP, PRMT5, MOV10, NXF1, HIST3H3, YEATS4, HUWE1, WIZ, ZSCAN5A | DYNLRB2 | APP, DYNC1I2, GTF2H2C, KIF7, DYNLT1, WDR60, WDR34, TCTEX1D2, PAFAH1B1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CDYL2_DYNLRB2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CDYL2_DYNLRB2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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