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Fusion gene ID: 6602 |
FusionGeneSummary for CDKAL1_EXOC2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDKAL1_EXOC2 | Fusion gene ID: 6602 | Hgene | Tgene | Gene symbol | CDKAL1 | EXOC2 | Gene ID | 54901 | 55770 |
| Gene name | CDK5 regulatory subunit associated protein 1 like 1 | exocyst complex component 2 | |
| Synonyms | - | SEC5|SEC5L1|Sec5p | |
| Cytomap | 6p22.3 | 6p25.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | threonylcarbamoyladenosine tRNA methylthiotransferasetRNA-t(6)A37 methylthiotransferase | exocyst complex component 2SEC5-like 1exocyst complex component Sec5 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5VV42 | Q96KP1 | |
| Ensembl transtripts involved in fusion gene | ENST00000274695, ENST00000378624, ENST00000378610, ENST00000476517, | ENST00000230449, ENST00000448181, ENST00000475028, | |
| Fusion gene scores | * DoF score | 23 X 12 X 11=3036 | 3 X 3 X 3=27 |
| # samples | 22 | 3 | |
| ** MAII score | log2(22/3036*10)=-3.78659636189081 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CDKAL1 [Title/Abstract] AND EXOC2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-DH-A66G-01A | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000274695 | ENST00000230449 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| 5CDS-5UTR | ENST00000274695 | ENST00000448181 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| 5CDS-intron | ENST00000274695 | ENST00000475028 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| In-frame | ENST00000378624 | ENST00000230449 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| 5CDS-5UTR | ENST00000378624 | ENST00000448181 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| 5CDS-intron | ENST00000378624 | ENST00000475028 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| In-frame | ENST00000378610 | ENST00000230449 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| 5CDS-5UTR | ENST00000378610 | ENST00000448181 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| 5CDS-intron | ENST00000378610 | ENST00000475028 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| intron-3CDS | ENST00000476517 | ENST00000230449 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| intron-5UTR | ENST00000476517 | ENST00000448181 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
| intron-intron | ENST00000476517 | ENST00000475028 | CDKAL1 | chr6 | 20758874 | + | EXOC2 | chr6 | 576882 | - |
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FusionProtFeatures for CDKAL1_EXOC2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDKAL1 | EXOC2 |
| Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position37 in tRNAs that read codons beginning with adenine.{ECO:0000269|PubMed:20584901}. | Component of the exocyst complex involved in the dockingof exocytic vesicles with fusion sites on the plasma membrane. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000274695 | + | 7 | 16 | 64_172 | 172 | 580 | Domain | MTTase N-terminal |
| Hgene | CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000378610 | + | 5 | 14 | 64_172 | 172 | 580 | Domain | MTTase N-terminal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000274695 | + | 7 | 16 | 431_493 | 172 | 580 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000378610 | + | 5 | 14 | 431_493 | 172 | 580 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000378624 | + | 6 | 14 | 431_493 | 102 | 489 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000378624 | + | 6 | 14 | 64_172 | 102 | 489 | Domain | MTTase N-terminal |
| Hgene | >CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000274695 | + | 7 | 16 | 556_578 | 172 | 580 | Transmembrane | Helical |
| Hgene | >CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000378610 | + | 5 | 14 | 556_578 | 172 | 580 | Transmembrane | Helical |
| Hgene | >CDKAL1 | chr6:20758874 | chr6:576882 | ENST00000378624 | + | 6 | 14 | 556_578 | 102 | 489 | Transmembrane | Helical |
| Tgene | EXOC2 | chr6:20758874 | chr6:576882 | ENST00000230449 | - | 10 | 28 | 240_260 | 397 | 925 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | EXOC2 | chr6:20758874 | chr6:576882 | ENST00000230449 | - | 10 | 28 | 8_93 | 397 | 925 | Domain | Note=IPT/TIG |
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FusionGeneSequence for CDKAL1_EXOC2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CDKAL1_ENST00000274695_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_700aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGNPGLHSP MLDLDNDTRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNV RQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVR CVMATLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLST KPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIE LKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQAR >In-frame_CDKAL1_ENST00000378624_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_630aa MLSRRYEGEIPKNICKRKKTVHQVTENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQI DRVVEVVEETIKGNPGLHSPMLDLDNDTRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVN GSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELSGQWLAHAIQTVRLTHESLTAL EIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEV CQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKIT QVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEE LSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAASSTMMKTX >In-frame_CDKAL1_ENST00000378610_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_700aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGNPGLHSP MLDLDNDTRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNV RQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVR CVMATLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLST KPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIE LKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQAR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CDKAL1_ENST00000274695_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_2100nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGA AACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAG GGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTAACCCAGGCCTGCACAGTCCC ATGTTGGATCTTGATAATGATACACGTCCCTCAGTGTTGGGCCATCTCAGTCAGACAGCGTCCCTGAAGAGGGGCAGCAGCTTTCAGTCT GGTCGAGACGACACGTGGAGATACAAAACTCCCCACAGGGTGGCCTTTGTTGAAAAATTGACAAAACTCGTCTTGAGCCAGCTGCCTAAC TTCTGGAAACTCTGGATCTCCTACGTTAATGGAAGCCTCTTCAGTGAGACTGCTGAGAAGTCAGGCCAGATTGAAAGATCAAAGAATGTA AGGCAAAGACAAAATGATTTTAAGAAAATGATTCAGGAAGTAATGCACTCCCTGGTGAAGCTTACCCGCGGAGCCCTGCTTCCCCTCAGC ATCCGGGATGGGGAAGCCAAGCAGTACGGAGGCTGGGAGGTGAAGTGCGAGCTCTCCGGACAGTGGCTCGCTCACGCCATCCAGACTGTA AGACTTACTCATGAATCGTTGACTGCCCTTGAAATTCCTAATGACCTGTTACAGACTATCCAGGATCTCATCTTGGATCTCCGAGTACGT TGCGTAATGGCCACGTTGCAGCACACGGCGGAAGAAATAAAGAGATTAGCTGAAAAAGAAGACTGGATTGTTGACAATGAAGGACTGACT TCTCTACCATGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTC TTCCAACAACCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACC AAGCCTGATGCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTG ACCTCAGAACAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAG CACAACTTCCAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAG TTGAAAGCAGATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTC AGAAACTATTTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTA TCCAAGGTGATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGA CTTGAAATCTGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCC CAGCTTTCCAGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAA >In-frame_CDKAL1_ENST00000378624_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_1890nt ATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGAAAATGCATCCGAT GCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAAC AAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATA GATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTAACCCAGGCCTGCACAGTCCCATGTTGGATCTTGATAATGATACACGTCCC TCAGTGTTGGGCCATCTCAGTCAGACAGCGTCCCTGAAGAGGGGCAGCAGCTTTCAGTCTGGTCGAGACGACACGTGGAGATACAAAACT CCCCACAGGGTGGCCTTTGTTGAAAAATTGACAAAACTCGTCTTGAGCCAGCTGCCTAACTTCTGGAAACTCTGGATCTCCTACGTTAAT GGAAGCCTCTTCAGTGAGACTGCTGAGAAGTCAGGCCAGATTGAAAGATCAAAGAATGTAAGGCAAAGACAAAATGATTTTAAGAAAATG ATTCAGGAAGTAATGCACTCCCTGGTGAAGCTTACCCGCGGAGCCCTGCTTCCCCTCAGCATCCGGGATGGGGAAGCCAAGCAGTACGGA GGCTGGGAGGTGAAGTGCGAGCTCTCCGGACAGTGGCTCGCTCACGCCATCCAGACTGTAAGACTTACTCATGAATCGTTGACTGCCCTT GAAATTCCTAATGACCTGTTACAGACTATCCAGGATCTCATCTTGGATCTCCGAGTACGTTGCGTAATGGCCACGTTGCAGCACACGGCG GAAGAAATAAAGAGATTAGCTGAAAAAGAAGACTGGATTGTTGACAATGAAGGACTGACTTCTCTACCATGTCAGTTTGAACAGTGCATC GTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAACCTAAAACACAGGAGGAGGTT TGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGATGCAGATATAGATACTACACAT CTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAACAGCGCCTTTTGATAGTCCTA AGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTCCAGGGAATAGAAAAAATCACA CAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCAGATCCCATCGTTGGCTCCTTA GAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTATTTAAAAGAAGCACTGGTGAAT ATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTGATAGAAGCAGTTTCTGAAGAG CTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATCTGTGCTTTGAGGGACACTGTG GCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCCAGTGGAGCAGATAAAAAGTTA CTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCTTCAACCATGATGAAAACATAA >In-frame_CDKAL1_ENST00000378610_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_2100nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGA AACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAG GGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTAACCCAGGCCTGCACAGTCCC ATGTTGGATCTTGATAATGATACACGTCCCTCAGTGTTGGGCCATCTCAGTCAGACAGCGTCCCTGAAGAGGGGCAGCAGCTTTCAGTCT GGTCGAGACGACACGTGGAGATACAAAACTCCCCACAGGGTGGCCTTTGTTGAAAAATTGACAAAACTCGTCTTGAGCCAGCTGCCTAAC TTCTGGAAACTCTGGATCTCCTACGTTAATGGAAGCCTCTTCAGTGAGACTGCTGAGAAGTCAGGCCAGATTGAAAGATCAAAGAATGTA AGGCAAAGACAAAATGATTTTAAGAAAATGATTCAGGAAGTAATGCACTCCCTGGTGAAGCTTACCCGCGGAGCCCTGCTTCCCCTCAGC ATCCGGGATGGGGAAGCCAAGCAGTACGGAGGCTGGGAGGTGAAGTGCGAGCTCTCCGGACAGTGGCTCGCTCACGCCATCCAGACTGTA AGACTTACTCATGAATCGTTGACTGCCCTTGAAATTCCTAATGACCTGTTACAGACTATCCAGGATCTCATCTTGGATCTCCGAGTACGT TGCGTAATGGCCACGTTGCAGCACACGGCGGAAGAAATAAAGAGATTAGCTGAAAAAGAAGACTGGATTGTTGACAATGAAGGACTGACT TCTCTACCATGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTC TTCCAACAACCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACC AAGCCTGATGCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTG ACCTCAGAACAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAG CACAACTTCCAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAG TTGAAAGCAGATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTC AGAAACTATTTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTA TCCAAGGTGATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGA CTTGAAATCTGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCC CAGCTTTCCAGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CDKAL1_ENST00000274695_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_3805nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATTCCAGGCATACAGA AAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTATGGCTATAAAATTA CAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAA AAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCA TTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTAACCCAGGCCTGCACAGTCCCATGTTGGATCTTG ATAATGATACACGTCCCTCAGTGTTGGGCCATCTCAGTCAGACAGCGTCCCTGAAGAGGGGCAGCAGCTTTCAGTCTGGTCGAGACGACA CGTGGAGATACAAAACTCCCCACAGGGTGGCCTTTGTTGAAAAATTGACAAAACTCGTCTTGAGCCAGCTGCCTAACTTCTGGAAACTCT GGATCTCCTACGTTAATGGAAGCCTCTTCAGTGAGACTGCTGAGAAGTCAGGCCAGATTGAAAGATCAAAGAATGTAAGGCAAAGACAAA ATGATTTTAAGAAAATGATTCAGGAAGTAATGCACTCCCTGGTGAAGCTTACCCGCGGAGCCCTGCTTCCCCTCAGCATCCGGGATGGGG AAGCCAAGCAGTACGGAGGCTGGGAGGTGAAGTGCGAGCTCTCCGGACAGTGGCTCGCTCACGCCATCCAGACTGTAAGACTTACTCATG AATCGTTGACTGCCCTTGAAATTCCTAATGACCTGTTACAGACTATCCAGGATCTCATCTTGGATCTCCGAGTACGTTGCGTAATGGCCA CGTTGCAGCACACGGCGGAAGAAATAAAGAGATTAGCTGAAAAAGAAGACTGGATTGTTGACAATGAAGGACTGACTTCTCTACCATGTC AGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAACCTA AAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGATGCAG ATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAACAGC GCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTCCAGG GAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCAGATC CCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTATTTAA AAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTGATAG AAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATCTGTG CTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCCAGTG GAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCTTCAA CCATGATGAAAACATAAATATCTGCCACATAAAAGAAGTCCAGGAAAATAACACGTAATAAGACTGTTCACTCTCTAAGTACCCTAAAGG TATTTGGTGTATTAAACATTGGGTTTGCCATTTTTCTCTTTTTTCTTCCTCTGACTTCGAAAATTGTTGGTATACATTTCAACCAAAATG ACCTCATTTGAAATGCCCAGGAAGTATTTGTTTTGCCATTCTTACTAGATCAGATCCTGTATGACTTTAAAATACATTTTAAAATATATT TTGCATCTCAGCAGAAGGTTGAGTGCTGCAGGAAGAGCTGCTTCTGCAGGGAGTTTTCTGGAATGGCGTGGCACATATTGAAGCATTTCT CAGTGTCCCGTTCACGGAAGCGCAGGCAGCTCCCACGACACACGGAGAGACTGACTGATACGAGATTTGGAAAGCTATGTAGACATCTTT GGAGCTCTTACTGTCCTAAACTGTACAGCTGTGCTTAAAACCCTCATTTCATATAAATGGCCTTAAGTTTTCTAATTCAAGCGGGTTTTT GGAAAAATTTATGGTCTCCATTAAAATACATATTACAACTGGGGTAGATTATTTGTGGTCCAGGTGTCTGTGATTTAACTTTGCGTTTTG CTATCTGATTTTTATTTTTCACAGGGCTAAGCATGAGCTTTCATTCTCACTCACTCTTAATTTGTCGTGCGTCACTACACATGCACGTGT TGCAGTCCCTGAGGCCCTGTGTGTTATCTGTGATGGAGTGTGAATGTGTAACGGGCACTGTGTTACACTCTGAGGTGTTGGCGGGGCGGT CGCAGACTTCAGGGTCCCCTAACGGAAAGGCCAGGCTCCGCGTGGACGGCCAACTCCCTGCCCGCTCCTTCAGCAGGTGACTGTCTCTGC CACTTCTTACCTGCTGAAGGATCTTGCTCAGTAGCTGGAACAATGCTGCTGTCACACAGTCTCTTCTCTGAAACTTCAGGATGCTCCTTG GTCACCAGGCAATGGGAGCTGTAGACCAGCCGCATGCACTTGCCCCACATTCACTGCTGACTGGCTTCACTGGAATAGGTTCAGGTCACC GGGACTTCTCTCAGAGTCAGCGGCCCACCCAACTCCCTCATACCGTCGCATCTGAAAATTTTCAGAGAGGAATTCTCTTTGTAGTCGGCT TGTCAGGGTTTTCAAGTTTTTCTATGGTTATTTTTAAATCTCTTTTTTTAAATGCTAAAATTAATGTCCTCATTAATGCAAGTAATTTTA GAGCACAGTGTAGCCATGTACAGTTTCCATTATTTAAAATAAATAAATGTGTTGGTTCATTTGGTGTATGGGGGGACATCATGGTAACTG GAAATGAAAGTTTAATCTTTCACAAATGTGCTTGATAAAGCTGTTAAGAATTGTCTTTCCTAAGTATGTTAACTGTTGTATCTAACTCAA CTGTGAGCTAAGTTTAAAAACTGCAATCATGAATGTTTGTGATATTTTAAATATCTACTACAGCACATTCAGCCAATAAAGAATCTGCCT >In-frame_CDKAL1_ENST00000378624_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_3692nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGAAAATGCATCCGATGCAGAT TTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAA ATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATAGATCGT GTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTAACCCAGGCCTGCACAGTCCCATGTTGGATCTTGATAATGATACACGTCCCTCAGTG TTGGGCCATCTCAGTCAGACAGCGTCCCTGAAGAGGGGCAGCAGCTTTCAGTCTGGTCGAGACGACACGTGGAGATACAAAACTCCCCAC AGGGTGGCCTTTGTTGAAAAATTGACAAAACTCGTCTTGAGCCAGCTGCCTAACTTCTGGAAACTCTGGATCTCCTACGTTAATGGAAGC CTCTTCAGTGAGACTGCTGAGAAGTCAGGCCAGATTGAAAGATCAAAGAATGTAAGGCAAAGACAAAATGATTTTAAGAAAATGATTCAG GAAGTAATGCACTCCCTGGTGAAGCTTACCCGCGGAGCCCTGCTTCCCCTCAGCATCCGGGATGGGGAAGCCAAGCAGTACGGAGGCTGG GAGGTGAAGTGCGAGCTCTCCGGACAGTGGCTCGCTCACGCCATCCAGACTGTAAGACTTACTCATGAATCGTTGACTGCCCTTGAAATT CCTAATGACCTGTTACAGACTATCCAGGATCTCATCTTGGATCTCCGAGTACGTTGCGTAATGGCCACGTTGCAGCACACGGCGGAAGAA ATAAAGAGATTAGCTGAAAAAGAAGACTGGATTGTTGACAATGAAGGACTGACTTCTCTACCATGTCAGTTTGAACAGTGCATCGTGTGT TCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGAGGCCAGTGTCTTCCAACAACCTAAAACACAGGAGGAGGTTTGCCAG CTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACAGTTGAGCACCAAGCCTGATGCAGATATAGATACTACACATCTCTCT GTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGACTTCAGCTTGACCTCAGAACAGCGCCTTTTGATAGTCCTAAGTAAT TGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACATTTTGAAAAGCACAACTTCCAGGGAATAGAAAAAATCACACAGGTT AGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAATTACATCGAGTTGAAAGCAGATCCCATCGTTGGCTCCTTAGAACCT GGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCCAACAGGTGTCAGAAACTATTTAAAAGAAGCACTGGTGAATATAATT GCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCCTCGGGTACTATCCAAGGTGATAGAAGCAGTTTCTGAAGAGCTCAGT CGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTTACAGGCGAGACTTGAAATCTGTGCTTTGAGGGACACTGTGGCTGTT TACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGAAGCCCTGCCCCAGCTTTCCAGTGGAGCAGATAAAAAGTTACTGGAA GAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCACCTGTTTCCAAGCAGCTTCTTCAACCATGATGAAAACATAAATATCT GCCACATAAAAGAAGTCCAGGAAAATAACACGTAATAAGACTGTTCACTCTCTAAGTACCCTAAAGGTATTTGGTGTATTAAACATTGGG TTTGCCATTTTTCTCTTTTTTCTTCCTCTGACTTCGAAAATTGTTGGTATACATTTCAACCAAAATGACCTCATTTGAAATGCCCAGGAA GTATTTGTTTTGCCATTCTTACTAGATCAGATCCTGTATGACTTTAAAATACATTTTAAAATATATTTTGCATCTCAGCAGAAGGTTGAG TGCTGCAGGAAGAGCTGCTTCTGCAGGGAGTTTTCTGGAATGGCGTGGCACATATTGAAGCATTTCTCAGTGTCCCGTTCACGGAAGCGC AGGCAGCTCCCACGACACACGGAGAGACTGACTGATACGAGATTTGGAAAGCTATGTAGACATCTTTGGAGCTCTTACTGTCCTAAACTG TACAGCTGTGCTTAAAACCCTCATTTCATATAAATGGCCTTAAGTTTTCTAATTCAAGCGGGTTTTTGGAAAAATTTATGGTCTCCATTA AAATACATATTACAACTGGGGTAGATTATTTGTGGTCCAGGTGTCTGTGATTTAACTTTGCGTTTTGCTATCTGATTTTTATTTTTCACA GGGCTAAGCATGAGCTTTCATTCTCACTCACTCTTAATTTGTCGTGCGTCACTACACATGCACGTGTTGCAGTCCCTGAGGCCCTGTGTG TTATCTGTGATGGAGTGTGAATGTGTAACGGGCACTGTGTTACACTCTGAGGTGTTGGCGGGGCGGTCGCAGACTTCAGGGTCCCCTAAC GGAAAGGCCAGGCTCCGCGTGGACGGCCAACTCCCTGCCCGCTCCTTCAGCAGGTGACTGTCTCTGCCACTTCTTACCTGCTGAAGGATC TTGCTCAGTAGCTGGAACAATGCTGCTGTCACACAGTCTCTTCTCTGAAACTTCAGGATGCTCCTTGGTCACCAGGCAATGGGAGCTGTA GACCAGCCGCATGCACTTGCCCCACATTCACTGCTGACTGGCTTCACTGGAATAGGTTCAGGTCACCGGGACTTCTCTCAGAGTCAGCGG CCCACCCAACTCCCTCATACCGTCGCATCTGAAAATTTTCAGAGAGGAATTCTCTTTGTAGTCGGCTTGTCAGGGTTTTCAAGTTTTTCT ATGGTTATTTTTAAATCTCTTTTTTTAAATGCTAAAATTAATGTCCTCATTAATGCAAGTAATTTTAGAGCACAGTGTAGCCATGTACAG TTTCCATTATTTAAAATAAATAAATGTGTTGGTTCATTTGGTGTATGGGGGGACATCATGGTAACTGGAAATGAAAGTTTAATCTTTCAC AAATGTGCTTGATAAAGCTGTTAAGAATTGTCTTTCCTAAGTATGTTAACTGTTGTATCTAACTCAACTGTGAGCTAAGTTTAAAAACTG CAATCATGAATGTTTGTGATATTTTAAATATCTACTACAGCACATTCAGCCAATAAAGAATCTGCCTTTAATGTAAGTTGTAATTTACTT >In-frame_CDKAL1_ENST00000378610_chr6_20758874_+_EXOC2_ENST00000230449_chr6_576882_-_3648nt GGTAGAGAATATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAG GCATTTTGTAAGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGA CAGCACTATTCCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCT AGCTGCTTATGGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGA CCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGA CTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTAACCCAGGCCT GCACAGTCCCATGTTGGATCTTGATAATGATACACGTCCCTCAGTGTTGGGCCATCTCAGTCAGACAGCGTCCCTGAAGAGGGGCAGCAG CTTTCAGTCTGGTCGAGACGACACGTGGAGATACAAAACTCCCCACAGGGTGGCCTTTGTTGAAAAATTGACAAAACTCGTCTTGAGCCA GCTGCCTAACTTCTGGAAACTCTGGATCTCCTACGTTAATGGAAGCCTCTTCAGTGAGACTGCTGAGAAGTCAGGCCAGATTGAAAGATC AAAGAATGTAAGGCAAAGACAAAATGATTTTAAGAAAATGATTCAGGAAGTAATGCACTCCCTGGTGAAGCTTACCCGCGGAGCCCTGCT TCCCCTCAGCATCCGGGATGGGGAAGCCAAGCAGTACGGAGGCTGGGAGGTGAAGTGCGAGCTCTCCGGACAGTGGCTCGCTCACGCCAT CCAGACTGTAAGACTTACTCATGAATCGTTGACTGCCCTTGAAATTCCTAATGACCTGTTACAGACTATCCAGGATCTCATCTTGGATCT CCGAGTACGTTGCGTAATGGCCACGTTGCAGCACACGGCGGAAGAAATAAAGAGATTAGCTGAAAAAGAAGACTGGATTGTTGACAATGA AGGACTGACTTCTCTACCATGTCAGTTTGAACAGTGCATCGTGTGTTCTCTGCAGTCACTGAAGGGGGTTCTGGAGTGCAAGCCGGGAGA GGCCAGTGTCTTCCAACAACCTAAAACACAGGAGGAGGTTTGCCAGCTAAGCATCAATATAATGCAGGTTTTTATATACTGTCTGGAACA GTTGAGCACCAAGCCTGATGCAGATATAGATACTACACATCTCTCTGTTGATGTTTCTTCCCCTGACTTGTTTGGAAGTATCCATGAAGA CTTCAGCTTGACCTCAGAACAGCGCCTTTTGATAGTCCTAAGTAATTGCTGCTATCTAGAACGTCACACCTTCCTAAATATCGCAGAACA TTTTGAAAAGCACAACTTCCAGGGAATAGAAAAAATCACACAGGTTAGCATGGCCTCATTGAAAGAACTAGATCAAAGACTCTTTGAAAA TTACATCGAGTTGAAAGCAGATCCCATCGTTGGCTCCTTAGAACCTGGAATTTATGCAGGATATTTTGATTGGAAGGACTGCCTGCCTCC AACAGGTGTCAGAAACTATTTAAAAGAAGCACTGGTGAATATAATTGCCGTGCATGCAGAGGTGTTCACCATTTCCAAAGAACTGGTCCC TCGGGTACTATCCAAGGTGATAGAAGCAGTTTCTGAAGAGCTCAGTCGACTGATGCAGTGTGTTTCATCCTTCAGCAAAAATGGAGCTTT ACAGGCGAGACTTGAAATCTGTGCTTTGAGGGACACTGTGGCTGTTTACCTGACACCCGAAAGCAAGTCAAGTTTTAAGCAGGCTTTGGA AGCCCTGCCCCAGCTTTCCAGTGGAGCAGATAAAAAGTTACTGGAAGAGCTCCTGAACAAGTTCAAGAGTAGCATGCACTTGCAGCTCAC CTGTTTCCAAGCAGCTTCTTCAACCATGATGAAAACATAAATATCTGCCACATAAAAGAAGTCCAGGAAAATAACACGTAATAAGACTGT TCACTCTCTAAGTACCCTAAAGGTATTTGGTGTATTAAACATTGGGTTTGCCATTTTTCTCTTTTTTCTTCCTCTGACTTCGAAAATTGT TGGTATACATTTCAACCAAAATGACCTCATTTGAAATGCCCAGGAAGTATTTGTTTTGCCATTCTTACTAGATCAGATCCTGTATGACTT TAAAATACATTTTAAAATATATTTTGCATCTCAGCAGAAGGTTGAGTGCTGCAGGAAGAGCTGCTTCTGCAGGGAGTTTTCTGGAATGGC GTGGCACATATTGAAGCATTTCTCAGTGTCCCGTTCACGGAAGCGCAGGCAGCTCCCACGACACACGGAGAGACTGACTGATACGAGATT TGGAAAGCTATGTAGACATCTTTGGAGCTCTTACTGTCCTAAACTGTACAGCTGTGCTTAAAACCCTCATTTCATATAAATGGCCTTAAG TTTTCTAATTCAAGCGGGTTTTTGGAAAAATTTATGGTCTCCATTAAAATACATATTACAACTGGGGTAGATTATTTGTGGTCCAGGTGT CTGTGATTTAACTTTGCGTTTTGCTATCTGATTTTTATTTTTCACAGGGCTAAGCATGAGCTTTCATTCTCACTCACTCTTAATTTGTCG TGCGTCACTACACATGCACGTGTTGCAGTCCCTGAGGCCCTGTGTGTTATCTGTGATGGAGTGTGAATGTGTAACGGGCACTGTGTTACA CTCTGAGGTGTTGGCGGGGCGGTCGCAGACTTCAGGGTCCCCTAACGGAAAGGCCAGGCTCCGCGTGGACGGCCAACTCCCTGCCCGCTC CTTCAGCAGGTGACTGTCTCTGCCACTTCTTACCTGCTGAAGGATCTTGCTCAGTAGCTGGAACAATGCTGCTGTCACACAGTCTCTTCT CTGAAACTTCAGGATGCTCCTTGGTCACCAGGCAATGGGAGCTGTAGACCAGCCGCATGCACTTGCCCCACATTCACTGCTGACTGGCTT CACTGGAATAGGTTCAGGTCACCGGGACTTCTCTCAGAGTCAGCGGCCCACCCAACTCCCTCATACCGTCGCATCTGAAAATTTTCAGAG AGGAATTCTCTTTGTAGTCGGCTTGTCAGGGTTTTCAAGTTTTTCTATGGTTATTTTTAAATCTCTTTTTTTAAATGCTAAAATTAATGT CCTCATTAATGCAAGTAATTTTAGAGCACAGTGTAGCCATGTACAGTTTCCATTATTTAAAATAAATAAATGTGTTGGTTCATTTGGTGT ATGGGGGGACATCATGGTAACTGGAAATGAAAGTTTAATCTTTCACAAATGTGCTTGATAAAGCTGTTAAGAATTGTCTTTCCTAAGTAT GTTAACTGTTGTATCTAACTCAACTGTGAGCTAAGTTTAAAAACTGCAATCATGAATGTTTGTGATATTTTAAATATCTACTACAGCACA |
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FusionGenePPI for CDKAL1_EXOC2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CDKAL1 | ELAVL1, MMS19, LMNA, FAM96B, CIAO1, LCK, SUZ12, TCTN2, TCTN3, EVC2, NEK8, TMEM237, TMEM17, TMEM216, FAF2, TTYH3, BPIFB1, DNM1, TYW3, DNM3, TYW1B | EXOC2 | EXOC8, RALB, RALA, SERGEF, VPS53, EXOC4, EXOC3, EXOC7, EXOC5, EXOC6, GET4, ESX1, TBK1, BECN1, USP33, KIAA0226, ATG14, PIK3C3, ULK1, SHMT2, MOV10, NXF1, BSG, LPAR6, PTGER3, SCN2B, SCARA3, HTR6, EXOC1, PGM1, SPTBN2, NTRK1, RANBP9, SNW1, CDC5L, PTAR1, IL1R2, EDNRB, APLNR, CHRM3, EXOC6B, CDKN2A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CDKAL1_EXOC2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CDKAL1_EXOC2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CDKAL1 | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 3 | CTD_human |
| Hgene | CDKAL1 | C0005910 | Body Weight | 2 | CTD_human |
| Hgene | CDKAL1 | C0005612 | Birth Weight | 1 | CTD_human |
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