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Fusion gene ID: 6451 |
FusionGeneSummary for CDH23_NSD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDH23_NSD1 | Fusion gene ID: 6451 | Hgene | Tgene | Gene symbol | CDH23 | NSD1 | Gene ID | 64072 | 64324 |
| Gene name | cadherin related 23 | nuclear receptor binding SET domain protein 1 | |
| Synonyms | CDHR23|PITA5|USH1D | ARA267|KMT3B|SOTOS|SOTOS1|STO | |
| Cytomap | 10q22.1 | 5q35.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cadherin-23cadherin-like 23cadherin-related family member 23otocadherin | histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specificH3-K36-HMTaseH4-K20-HMTaseNR-binding SET domain-containing proteinandrogen receptor coactivator 267 kDa proteinandrogen receptor-associated coregulator 267androgen receptor-as | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q9H251 | Q96L73 | |
| Ensembl transtripts involved in fusion gene | ENST00000398842, ENST00000398809, ENST00000461841, ENST00000299366, ENST00000224721, ENST00000398788, ENST00000475158, | ENST00000354179, ENST00000439151, ENST00000347982, ENST00000361032, ENST00000511258, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 7 X 7 X 4=196 |
| # samples | 5 | 10 | |
| ** MAII score | log2(5/32*10)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(10/196*10)=-0.970853654340483 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CDH23 [Title/Abstract] AND NSD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NSD1 | GO:0045893 | positive regulation of transcription, DNA-templated | 11509567 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-AN-A0FJ-01A | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000398842 | ENST00000354179 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398842 | ENST00000439151 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398842 | ENST00000347982 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000398842 | ENST00000361032 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000398842 | ENST00000511258 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398809 | ENST00000354179 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398809 | ENST00000439151 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398809 | ENST00000347982 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000398809 | ENST00000361032 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000398809 | ENST00000511258 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000461841 | ENST00000354179 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000461841 | ENST00000439151 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000461841 | ENST00000347982 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000461841 | ENST00000361032 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000461841 | ENST00000511258 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000299366 | ENST00000354179 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000299366 | ENST00000439151 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000299366 | ENST00000347982 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000299366 | ENST00000361032 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000299366 | ENST00000511258 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| In-frame | ENST00000224721 | ENST00000354179 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| In-frame | ENST00000224721 | ENST00000439151 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| In-frame | ENST00000224721 | ENST00000347982 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| 5CDS-intron | ENST00000224721 | ENST00000361032 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| 5CDS-intron | ENST00000224721 | ENST00000511258 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398788 | ENST00000354179 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398788 | ENST00000439151 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000398788 | ENST00000347982 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000398788 | ENST00000361032 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000398788 | ENST00000511258 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000475158 | ENST00000354179 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000475158 | ENST00000439151 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-3CDS | ENST00000475158 | ENST00000347982 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000475158 | ENST00000361032 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
| intron-intron | ENST00000475158 | ENST00000511258 | CDH23 | chr10 | 73501678 | + | NSD1 | chr5 | 176618885 | + |
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FusionProtFeatures for CDH23_NSD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDH23 | NSD1 |
| Histone methyltransferase. Preferentially methylates'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro).Transcriptional intermediary factor capable of both negatively orpositively influencing transcription, depending on the cellularcontext. {ECO:0000269|PubMed:21196496}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for CDH23_NSD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000354179_chr5_176618885_+_4008aa MGRHVATSCHVAWLLVLISGCWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLR QPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGTPIFIVNATDPDLGAGGSVLYSFQPPS QFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDK GRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSV AITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIA RDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSR PLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEG STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDP DLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPF VAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHV LDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDN GPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP LDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGK FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQ ITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVG QRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPP VIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLS CQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLR RRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADE KEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAK KEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAF DRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSS SISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDS SDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSP GRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSK LRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRGGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDP GKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTP SASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQK KVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALES EELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAA KMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLE CLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAANPANVSASKGRLM RCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCK AGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQ EAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGG RCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFM NHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRT QGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGR LSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSTGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSR PQPLDKVRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTS VPTGLRLPPPDRLLITSSPKPQTSDRPTDKPHASLSQRLPPPEKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKERA ASPHQVTPQADEKMPVLESSSWPASKGLGHMPRAVEKGCVSDPLQTSGKAAAPSEDPWQAVKSLTQARLLSQPPAKAFLYEPTTQASGRA SAGAEQTPGPLSQSPGLVKQAKQMVGGQQLPALAAKSGQSFRSLGKAPASLPTEEKKLVTTEQSPWALGKASSRAGLWPIVAGQTLAQSC >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000439151_chr5_176618885_+_4008aa MGRHVATSCHVAWLLVLISGCWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLR QPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGTPIFIVNATDPDLGAGGSVLYSFQPPS QFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDK GRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSV AITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIA RDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSR PLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEG STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDP DLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPF VAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHV LDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDN GPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP LDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGK FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQ ITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVG QRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPP VIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLS CQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLR RRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADE KEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAK KEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAF DRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSS SISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDS SDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSP GRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSK LRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRGGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDP GKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTP SASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQK KVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALES EELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAA KMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLE CLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAANPANVSASKGRLM RCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCK AGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQ EAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGG RCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFM NHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRT QGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGR LSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSTGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSR PQPLDKVRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTS VPTGLRLPPPDRLLITSSPKPQTSDRPTDKPHASLSQRLPPPEKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKERA ASPHQVTPQADEKMPVLESSSWPASKGLGHMPRAVEKGCVSDPLQTSGKAAAPSEDPWQAVKSLTQARLLSQPPAKAFLYEPTTQASGRA SAGAEQTPGPLSQSPGLVKQAKQMVGGQQLPALAAKSGQSFRSLGKAPASLPTEEKKLVTTEQSPWALGKASSRAGLWPIVAGQTLAQSC >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000347982_chr5_176618885_+_4008aa MGRHVATSCHVAWLLVLISGCWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLR QPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGTPIFIVNATDPDLGAGGSVLYSFQPPS QFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDK GRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSV AITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIA RDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSR PLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEG STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDP DLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPF VAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHV LDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDN GPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP LDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGK FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQ ITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVG QRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPP VIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLS CQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLR RRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADE KEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISGDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAK KEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAF DRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSS SISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDS SDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSP GRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSK LRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRGGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDP GKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTP SASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQK KVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALES EELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCYEAGHLENGITESCATSYSKDFGGGTTKIFDKPRKRKRQRHAAA KMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLE CLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAANPANVSASKGRLM RCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCK AGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQ EAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGG RCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFM NHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKFKKKQQGKRRT QGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGR LSCTEHDPCGPNPLEPGEIREYVPPPVPLPPGPSTHLAEQSTGMAAQAPKMSDKPPADTNQMLSLSKKALAGTCQRPLLPERPLERTDSR PQPLDKVRDLAGSGTKSQSLVSSQRPLDRPPAVAGPRPQLSDKPSPVTSPSSSPSVRSQPLERPLGTADPRLDKSIGAASPRPQSLEKTS VPTGLRLPPPDRLLITSSPKPQTSDRPTDKPHASLSQRLPPPEKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLIDLTPRQKERA ASPHQVTPQADEKMPVLESSSWPASKGLGHMPRAVEKGCVSDPLQTSGKAAAPSEDPWQAVKSLTQARLLSQPPAKAFLYEPTTQASGRA SAGAEQTPGPLSQSPGLVKQAKQMVGGQQLPALAAKSGQSFRSLGKAPASLPTEEKKLVTTEQSPWALGKASSRAGLWPIVAGQTLAQSC |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000354179_chr5_176618885_+_12024nt ATGGGGCGCCATGTTGCCACCAGCTGCCACGTGGCCTGGCTTTTGGTGCTGATCTCTGGATGCTGGGGCCAGGTGAACCGGCTGCCCTTC TTCACCAACCACTTCTTTGATACATACCTGCTGATCAGCGAGGACACGCCTGTGGGTTCTTCTGTGACCCAGTTGCTGGCCCAAGACATG GACAATGACCCCCTGGTGTTTGGCGTGTCTGGGGAGGAGGCCTCTCGCTTCTTTGCAGTGGAGCCTGACACTGGCGTGGTGTGGCTCCGG CAGCCACTGGACAGAGAGACCAAGTCAGAGTTCACCGTGGAGTTCTCTGTCAGCGACCACCAGGGGGTGATCACACGGAAGGTGAACATC CAGGTTGGGGATGTGAATGACAACGCGCCCACATTTCACAATCAGCCCTACAGCGTCCGCATCCCTGAGGTAGGAGCCACTGGGAATACA CCAGTGGGGACGCCCATCTTCATCGTGAATGCCACAGACCCCGACTTGGGGGCAGGGGGCAGCGTCCTCTACTCCTTCCAGCCCCCCTCC CAATTCTTCGCCATTGACAGCGCCCGCGGTATCGTCACAGTGATCCGGGAGCTGGACTACGAGACCACACAGGCCTACCAGCTCACGGTC AACGCCACAGATCAAGACAAGACCAGGCCTCTGTCCACCCTGGCCAACTTGGCCATCATCATCACAGATGTCCAGGACATGGACCCCATC TTCATCAACCTGCCTTACAGCACCAACATCTACGAGCATTCTCCTCCGGGCACGACGGTGCGCATCATCACCGCCATAGACCAGGATAAA GGACGTCCCCGGGGCATTGGCTACACCATCGTTTCAGGGAATACCAACAGCATCTTTGCCCTGGACTACATCAGCGGAGTGCTGACCTTG AATGGCCTGCTGGACCGGGAGAACCCCCTGTACAGCCATGGCTTCATCCTGACTGTGAAGGGCACGGAGCTGAACGATGACCGCACCCCA TCTGACGCTACAGTCACCACGACCTTCAATATCCTGGTTATTGACATCAATGACAATGCCCCGGAGTTCAACAGCTCCGAGTACAGCGTG GCCATCACTGAGCTGGCACAGGTCGGCTTTGCCCTTCCACTCTTCATCCAGGTGGTGGACAAGGATGAGAATTTGGGCCTGAACAGCATG TTTGAGGTGTACTTGGTGGGGAACAACTCCCACCACTTCATCATCTCCCCGACCTCCGTCCAGGGGAAGGCGGACATTCGTATTCGGGTG GCCATCCCACTGGACTACGAGACCGTGGACCGCTACGACTTTGATCTCTTTGCCAATGAGAGTGTGCCTGACCATGTGGGCTATGCCAAG GTGAAGATCACTCTCATCAATGAAAATGACAACCGGCCCATCTTCAGCCAGCCACTGTACAACATCAGCCTGTACGAGAACGTCACCGTG GGGACCTCTGTGCTGACAGTCCTGGCAACTGACAATGATGCAGGCACCTTTGGGGAAGTCAGCTACTTCTTCAGTGATGACCCTGACAGG TTCTCGCTGGACAAGGACACGGGACTCATCATGCTGATTGCCAGGCTGGACTATGAGCTCATCCAGCGCTTCACCCTGACGATCATTGCC CGGGACGGGGGCGGCGAGGAGACCACAGGCCGGGTCAGGATCAATGTGTTGGATGTCAACGACAACGTGCCCACCTTCCAGAAGGATGCC TACGTGGGTGCTCTGCGGGAGAACGAGCCTTCTGTCACACAGCTGGTGCGGCTCCGGGCAACAGATGAAGACTCCCCTCCCAACAACCAG ATCACCTACAGCATTGTCAGTGCATCTGCCTTTGGCAGCTACTTCGACATCAGCCTGTACGAGGGCTATGGAGTGATCAGCGTCAGTCGC CCCCTGGATTATGAACAGATATCCAATGGGCTGATTTATCTGACGGTCATGGCCATGGATGCTGGCAACCCCCCTCTCAACAGCACCGTC CCTGTCACCATCGAGGTGTTTGATGAGAATGACAACCCTCCCACCTTCAGCAAGCCCGCCTACTTCGTCTCCGTGGTGGAGAACATCATG GCAGGAGCCACGGTGCTGTTCCTGAATGCCACAGACCTGGACCGCTCCCGGGAGTACGGCCAGGAGTCCATCATCTACTCCTTGGAAGGC TCCACCCAGTTTCGGATCAATGCCCGCTCAGGGGAAATCACCACCACGTCTCTGCTTGACCGAGAGACCAAGTCTGAATACATCCTCATC GTTCGCGCAGTGGACGGGGGTGTGGGCCACAACCAGAAAACTGGCATCGCCACCGTAAACATCACCCTCCTGGACATCAATGACAACCAC CCCACGTGGAAGGACGCACCCTACTACATCAACCTGGTGGAGATGACCCCTCCAGACTCTGATGTGACCACGGTGGTGGCTGTTGACCCA GACCTGGGGGAGAATGGCACCCTGGTGTACAGCATCCAGCCACCCAACAAGTTCTACAGCCTCAACAGCACCACGGGCAAGATCCGCACC ACCCACGCCATGCTGGACCGGGAGAACCCCGACCCCCATGAGGCCGAGCTGATGCGCAAAATCGTCGTCTCTGTTACTGACTGTGGCAGG CCCCCTCTGAAAGCCACCAGCAGTGCCACAGTGTTTGTGAACCTCTTGGATCTCAATGACAATGACCCCACCTTTCAGAACCTGCCTTTT GTGGCCGAGGTGCTTGAAGGCATCCCGGCGGGGGTCTCCATCTACCAAGTGGTGGCCATCGACCTCGATGAGGGCCTGAACGGCCTGGTG TCCTACCGCATGCCGGTGGGCATGCCCCGCATGGACTTCCTCATCAACAGCAGCAGCGGCGTGGTGGTCACCACCACCGAGCTGGACCGC GAGCGCATCGCGGAGTACCAGCTGCGGGTGGTGGCCAGTGATGCAGGCACGCCCACCAAGAGCTCCACCAGCACGCTCACCATCCATGTG CTGGATGTGAACGACGAGACGCCCACCTTCTTCCCGGCCGTGTACAATGTGTCTGTGTCCGAGGACGTGCCACGCGAGTTCCGGGTGGTC TGGCTGAACTGCACGGACAACGACGTGGGCCTCAATGCAGAGCTCAGCTACTTCATCACAGGTGGCAACGTGGATGGGAAGTTCAGCGTG GGTTACCGCGATGCCGTTGTGAGAACCGTGGTGGGCCTGGACCGGGAGACCACAGCCGCCTACATGCTCATCCTGGAGGCCATCGACAAC GGCCCTGTAGGGAAGCGACACACGGGCACAGCCACCGTGTTCGTCACTGTCCTGGATGTGAATGACAACCGGCCCATCTTTCTGCAGAGC AGCTATGAGGCCAGCGTCCCTGAGGACATCCCTGAAGGCCACAGCATCTTGCAGCTGAAAGCCACGGACGCAGATGAGGGCGAGTTTGGG CGTGTGTGGTACCGCATCCTCCATGGTAACCATGGCAACAACTTCCGGATCCATGTCAGCAATGGGCTCCTGATGCGAGGGCCCCGGCCC CTGGACCGGGAGCGGAACTCATCCCACGTGCTGATAGTGGAGGCCTACAACCACGACCTGGGCCCCATGCGGAGCTCCGTCAGGGTGATT GTGTACGTGGAGGACATCAACGATGAGGCCCCCGTGTTCACACAGCAGCAGTACAGCCGTCTGGGGCTTCGAGAGACCGCAGGCATTGGA ACGTCAGTCATCGTGGTCCAAGCCACAGACCGAGACTCTGGGGATGGTGGCCTGGTGAACTACCGCATCCTGTCGGGCGCAGAGGGGAAG TTTGAGATTGACGAGAGCACAGGGCTTATCATCACCGTGAATTACCTGGACTACGAGACCAAGACCAGCTACATGATGAATGTGTCGGCC ACTGACCAGGCCCCGCCCTTCAACCAGGGCTTCTGCAGCGTCTACATCACTCTGCTCAACGAGCTGGACGAGGCCGTGCAGTTCTCCAAT GCCTCATACGAGGCTGCCATCCTGGAGAATCTGGCACTGGGTACTGAGATTGTGCGGGTCCAGGCCTACTCCATCGACAACCTCAACCAA ATCACGTACCGCTTCAACGCCTACACCAGCACCCAGGCCAAAGCCCTCTTCAAGATAGACGCCATCACGGGTGTGATCACAGTCCAGGGC CTGGTGGACCGTGAGAAGGGCGACTTCTATACCTTGACAGTGGTGGCAGATGACGGCGGCCCCAAGGTGGACTCCACCGTGAAGGTCTAC ATCACTGTGCTGGACGAGAATGACAACAGCCCCCGGTTTGACTTCACCTCCGACTCGGCGGTCAGCATACCCGAGGACTGCCCTGTGGGC CAGCGAGTGGCTACTGTCAAGGCCTGGGACCCTGATGCTGGCAGCAATGGGCAGGTGGTCTTCTCCCTGGCCTCTGGCAACATCGCGGGG GCCTTTGAGATCGTCACCACCAATGACTCCATTGGCGAAGTGTTTGTGGCCAGGCCCCTGGACAGAGAAGAGCTGGATCACTACATCCTC CAGGTTGTGGCTTCTGACCGAGGCACCCCTCCACGGAAGAAGGACCACATCCTGCAGGTGACCATCCTGGACATCAATGACAACCCTCCA GTCATCGAGAGCCCCTTTGGATACAATGTCAGTGTGAATGAGAACGTGGGTGGAGGTACTGCTGTGGTCCAGGTGAGAGCCACTGACCGT GACATCGGGATCAACAGTGTTCTGTCCTACTACATCACCGAGGGCAACAAGGACATGGCCTTCCGCATGGACCGCATCAGCGGTGAGATC GCCACACGGCCTGCCCCGCCTGACCGCGAGCGCCAGAGCTTCTACCACCTGGTGGCCACTGTGGAGGACGAGGGCACCCCAACCCTGTCG TGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGC AGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTT GGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCCTTAGG AGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAA CAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGAC TGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAG AAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAA GCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAAT GAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAG AAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCC CAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGT ACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTC GATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAA CAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAAT CTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCA AGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGT ATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACC AAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCA AGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCT GGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACA TTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCT GGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGA GATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTG TCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAA TTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTT CCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGAT CCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCT GGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAAT GGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAG AAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCT TCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAA TCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCA GAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAG AAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAG GTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCA GAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCT GAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGAC CCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAATCTTGT GCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTGCAGCC AAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGGCCACA AGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAGGAGCT GCACTCAAGGAGAATGTCTGTCAGAATTGTGAAAAATTGGGTGAGCTGCTGTTATGTGAGGCTCAGTGCTGTGGGGCTTTCCACCTGGAG TGCCTTGGATTGACTGAGATGCCAAGAGGAAAATTTATCTGCAATGAATGTCGCACAGGAATCCATACCTGTTTTGTATGTAAGCAGAGT GGGGAAGATGTTAAAAGGTGCCTTCTACCCTTGTGTGGAAAGTTTTACCATGAAGAGTGTGTCCAGAAGTACCCACCCACTGTTATGCAG AACAAGGGCTTCCGGTGCTCCCTCCACATCTGTATAACCTGTCATGCTGCTAATCCAGCCAATGTTTCTGCATCTAAAGGTCGGTTGATG CGCTGTGTCCGCTGTCCTGTGGCATACCACGCCAATGACTTTTGCCTGGCTGCTGGGTCAAAGATCCTTGCATCTAATAGTATCATCTGC CCTAATCACTTTACCCCTAGGCGGGGCTGCCGAAATCATGAGCATGTTAATGTTAGCTGGTGCTTTGTGTGCTCAGAAGGAGGCAGCCTT CTGTGCTGTGATTCTTGCCCTGCTGCTTTTCATCGTGAATGCCTGAACATTGATATCCCTGAAGGAAACTGGTATTGCAATGACTGTAAA GCAGGCAAAAAGCCACACTACAGGGAGATTGTCTGGGTAAAAGTTGGACGATACAGGTGGTGGCCAGCTGAGATCTGCCATCCTCGAGCT GTTCCTTCCAACATTGATAAGATGAGACATGATGTGGGAGAGTTCCCAGTCCTCTTTTTTGGATCTAATGACTATTTGTGGACTCACCAG GCCCGAGTCTTCCCTTACATGGAGGGTGACGTGAGCAGCAAGGATAAGATGGGCAAAGGAGTGGATGGGACATATAAAAAAGCTCTTCAG GAAGCTGCAGCAAGGTTTGAGGAATTAAAGGCCCAAAAAGAGCTAAGACAGCTGCAGGAAGACCGAAAGAATGACAAGAAGCCACCACCT TATAAACATATAAAGGTAAACCGTCCTATTGGCAGGGTACAGATCTTCACTGCAGACTTATCTGAAATACCCCGTTGCAACTGTAAAGCT ACTGATGAGAACCCCTGTGGGATAGACTCTGAATGCATCAACCGCATGCTGCTCTATGAGTGCCACCCCACAGTGTGTCCTGCCGGAGGG CGCTGTCAAAACCAGTGCTTTTCCAAGCGCCAATATCCAGAGGTTGAAATTTTCCGCACATTACAGCGGGGTTGGGGTCTACGGACAAAA ACAGATATTAAAAAGGGTGAATTTGTGAATGAGTATGTGGGTGAGCTTATAGATGAAGAAGAATGCAGAGCTCGAATTCGCTATGCTCAA GAACATGATATCACTAATTTCTATATGCTCACCCTAGACAAAGACCGAATCATTGATGCTGGTCCCAAAGGAAACTATGCTCGGTTCATG AATCATTGCTGCCAGCCCAACTGTGAAACACAGAAGTGGTCTGTGAATGGAGATACCCGTGTAGGCCTTTTTGCACTAAGTGACATTAAA GCAGGCACTGAACTTACCTTCAACTACAACCTAGAATGTCTTGGGAATGGAAAGACTGTTTGCAAATGTGGAGCCCCGAACTGCAGTGGC TTCTTGGGTGTAAGGCCAAAGAATCAACCCATTGCCACGGAAGAAAAGTCAAAGAAATTCAAGAAGAAGCAACAGGGAAAGCGCAGGACC CAGGGTGAAATCACAAAGGAGCGAGAAGATGAGTGTTTTAGTTGTGGGGATGCTGGCCAGCTCGTCTCCTGCAAGAAACCAGGCTGCCCA AAAGTTTACCACGCAGACTGTCTCAATCTGACCAAGCGACCAGCAGGGAAATGGGAATGTCCGTGGCATCAGTGTGACATCTGCGGGAAG GAAGCAGCCTCCTTCTGTGAGATGTGCCCCAGCTCCTTTTGTAAGCAGCATCGAGAAGGGATGCTTTTCATTTCCAAACTGGATGGGCGT CTGTCTTGTACTGAGCATGACCCCTGTGGGCCCAATCCTCTGGAACCTGGGGAGATCCGTGAGTATGTGCCTCCCCCAGTACCGCTGCCT CCAGGGCCAAGCACTCACCTGGCAGAGCAATCAACAGGAATGGCTGCTCAGGCACCCAAAATGTCAGATAAACCTCCTGCTGACACCAAC CAGATGCTGTCGCTCTCCAAAAAAGCTCTGGCAGGGACTTGTCAGAGGCCATTGCTACCTGAAAGACCTCTTGAGAGAACTGACTCCAGG CCCCAGCCTTTAGATAAGGTCAGAGACCTCGCTGGGTCAGGGACCAAATCCCAATCCTTGGTTTCCAGCCAGAGGCCACTGGACAGGCCA CCAGCAGTGGCAGGACCAAGACCCCAGCTAAGCGACAAACCCTCTCCAGTGACCAGCCCAAGCTCCTCACCCTCAGTCAGGTCCCAACCA CTGGAAAGACCTCTGGGGACGGCTGACCCAAGGCTGGATAAATCCATAGGTGCTGCCAGCCCAAGGCCCCAGTCACTGGAGAAAACCTCA GTTCCCACTGGCCTGAGACTTCCGCCGCCAGACAGACTGCTCATTACTAGCAGTCCCAAACCCCAGACTTCAGACAGGCCTACTGACAAA CCCCATGCCTCTTTGTCCCAGAGACTCCCACCTCCTGAGAAAGTACTATCAGCTGTGGTCCAGACCCTTGTAGCTAAAGAAAAAGCACTG AGGCCTGTGGACCAGAATACTCAGTCAAAAAATAGAGCTGCTTTGGTGATGGATCTCATAGACCTAACTCCTCGCCAGAAGGAGCGGGCA GCTTCACCTCATCAGGTCACACCACAGGCTGATGAGAAGATGCCAGTGTTGGAGTCAAGTTCATGGCCTGCCAGCAAAGGTCTGGGGCAT ATGCCGAGAGCTGTTGAGAAAGGCTGTGTGTCAGATCCTCTTCAGACATCTGGGAAAGCAGCAGCCCCTTCAGAGGACCCCTGGCAAGCT GTTAAATCACTCACCCAGGCCAGACTTCTTTCTCAGCCTCCTGCCAAGGCCTTTTTATATGAGCCAACAACTCAGGCCTCAGGAAGAGCT TCTGCAGGGGCTGAGCAGACCCCAGGGCCTCTTAGCCAATCCCCGGGCCTGGTGAAGCAGGCGAAGCAGATGGTCGGAGGCCAGCAACTA CCTGCACTTGCCGCCAAGAGTGGGCAATCTTTTAGGTCTCTCGGGAAGGCCCCAGCCTCCCTCCCCACTGAAGAAAAGAAGTTGGTAACC ACAGAGCAAAGTCCCTGGGCCCTGGGAAAAGCCTCATCACGGGCAGGGCTCTGGCCCATAGTGGCTGGACAGACACTGGCACAGTCTTGC TGGTCTGCTGGGAGCACACAGACATTGGCACAGACTTGCTGGTCTCTTGGAAGAGGGCAAGACCCCAAACCAGAGCAAAATACACTTCCA >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000439151_chr5_176618885_+_12024nt ATGGGGCGCCATGTTGCCACCAGCTGCCACGTGGCCTGGCTTTTGGTGCTGATCTCTGGATGCTGGGGCCAGGTGAACCGGCTGCCCTTC TTCACCAACCACTTCTTTGATACATACCTGCTGATCAGCGAGGACACGCCTGTGGGTTCTTCTGTGACCCAGTTGCTGGCCCAAGACATG GACAATGACCCCCTGGTGTTTGGCGTGTCTGGGGAGGAGGCCTCTCGCTTCTTTGCAGTGGAGCCTGACACTGGCGTGGTGTGGCTCCGG CAGCCACTGGACAGAGAGACCAAGTCAGAGTTCACCGTGGAGTTCTCTGTCAGCGACCACCAGGGGGTGATCACACGGAAGGTGAACATC CAGGTTGGGGATGTGAATGACAACGCGCCCACATTTCACAATCAGCCCTACAGCGTCCGCATCCCTGAGGTAGGAGCCACTGGGAATACA CCAGTGGGGACGCCCATCTTCATCGTGAATGCCACAGACCCCGACTTGGGGGCAGGGGGCAGCGTCCTCTACTCCTTCCAGCCCCCCTCC CAATTCTTCGCCATTGACAGCGCCCGCGGTATCGTCACAGTGATCCGGGAGCTGGACTACGAGACCACACAGGCCTACCAGCTCACGGTC AACGCCACAGATCAAGACAAGACCAGGCCTCTGTCCACCCTGGCCAACTTGGCCATCATCATCACAGATGTCCAGGACATGGACCCCATC TTCATCAACCTGCCTTACAGCACCAACATCTACGAGCATTCTCCTCCGGGCACGACGGTGCGCATCATCACCGCCATAGACCAGGATAAA GGACGTCCCCGGGGCATTGGCTACACCATCGTTTCAGGGAATACCAACAGCATCTTTGCCCTGGACTACATCAGCGGAGTGCTGACCTTG AATGGCCTGCTGGACCGGGAGAACCCCCTGTACAGCCATGGCTTCATCCTGACTGTGAAGGGCACGGAGCTGAACGATGACCGCACCCCA TCTGACGCTACAGTCACCACGACCTTCAATATCCTGGTTATTGACATCAATGACAATGCCCCGGAGTTCAACAGCTCCGAGTACAGCGTG GCCATCACTGAGCTGGCACAGGTCGGCTTTGCCCTTCCACTCTTCATCCAGGTGGTGGACAAGGATGAGAATTTGGGCCTGAACAGCATG TTTGAGGTGTACTTGGTGGGGAACAACTCCCACCACTTCATCATCTCCCCGACCTCCGTCCAGGGGAAGGCGGACATTCGTATTCGGGTG GCCATCCCACTGGACTACGAGACCGTGGACCGCTACGACTTTGATCTCTTTGCCAATGAGAGTGTGCCTGACCATGTGGGCTATGCCAAG GTGAAGATCACTCTCATCAATGAAAATGACAACCGGCCCATCTTCAGCCAGCCACTGTACAACATCAGCCTGTACGAGAACGTCACCGTG GGGACCTCTGTGCTGACAGTCCTGGCAACTGACAATGATGCAGGCACCTTTGGGGAAGTCAGCTACTTCTTCAGTGATGACCCTGACAGG TTCTCGCTGGACAAGGACACGGGACTCATCATGCTGATTGCCAGGCTGGACTATGAGCTCATCCAGCGCTTCACCCTGACGATCATTGCC CGGGACGGGGGCGGCGAGGAGACCACAGGCCGGGTCAGGATCAATGTGTTGGATGTCAACGACAACGTGCCCACCTTCCAGAAGGATGCC TACGTGGGTGCTCTGCGGGAGAACGAGCCTTCTGTCACACAGCTGGTGCGGCTCCGGGCAACAGATGAAGACTCCCCTCCCAACAACCAG ATCACCTACAGCATTGTCAGTGCATCTGCCTTTGGCAGCTACTTCGACATCAGCCTGTACGAGGGCTATGGAGTGATCAGCGTCAGTCGC CCCCTGGATTATGAACAGATATCCAATGGGCTGATTTATCTGACGGTCATGGCCATGGATGCTGGCAACCCCCCTCTCAACAGCACCGTC CCTGTCACCATCGAGGTGTTTGATGAGAATGACAACCCTCCCACCTTCAGCAAGCCCGCCTACTTCGTCTCCGTGGTGGAGAACATCATG GCAGGAGCCACGGTGCTGTTCCTGAATGCCACAGACCTGGACCGCTCCCGGGAGTACGGCCAGGAGTCCATCATCTACTCCTTGGAAGGC TCCACCCAGTTTCGGATCAATGCCCGCTCAGGGGAAATCACCACCACGTCTCTGCTTGACCGAGAGACCAAGTCTGAATACATCCTCATC GTTCGCGCAGTGGACGGGGGTGTGGGCCACAACCAGAAAACTGGCATCGCCACCGTAAACATCACCCTCCTGGACATCAATGACAACCAC CCCACGTGGAAGGACGCACCCTACTACATCAACCTGGTGGAGATGACCCCTCCAGACTCTGATGTGACCACGGTGGTGGCTGTTGACCCA GACCTGGGGGAGAATGGCACCCTGGTGTACAGCATCCAGCCACCCAACAAGTTCTACAGCCTCAACAGCACCACGGGCAAGATCCGCACC ACCCACGCCATGCTGGACCGGGAGAACCCCGACCCCCATGAGGCCGAGCTGATGCGCAAAATCGTCGTCTCTGTTACTGACTGTGGCAGG CCCCCTCTGAAAGCCACCAGCAGTGCCACAGTGTTTGTGAACCTCTTGGATCTCAATGACAATGACCCCACCTTTCAGAACCTGCCTTTT GTGGCCGAGGTGCTTGAAGGCATCCCGGCGGGGGTCTCCATCTACCAAGTGGTGGCCATCGACCTCGATGAGGGCCTGAACGGCCTGGTG TCCTACCGCATGCCGGTGGGCATGCCCCGCATGGACTTCCTCATCAACAGCAGCAGCGGCGTGGTGGTCACCACCACCGAGCTGGACCGC GAGCGCATCGCGGAGTACCAGCTGCGGGTGGTGGCCAGTGATGCAGGCACGCCCACCAAGAGCTCCACCAGCACGCTCACCATCCATGTG CTGGATGTGAACGACGAGACGCCCACCTTCTTCCCGGCCGTGTACAATGTGTCTGTGTCCGAGGACGTGCCACGCGAGTTCCGGGTGGTC TGGCTGAACTGCACGGACAACGACGTGGGCCTCAATGCAGAGCTCAGCTACTTCATCACAGGTGGCAACGTGGATGGGAAGTTCAGCGTG GGTTACCGCGATGCCGTTGTGAGAACCGTGGTGGGCCTGGACCGGGAGACCACAGCCGCCTACATGCTCATCCTGGAGGCCATCGACAAC GGCCCTGTAGGGAAGCGACACACGGGCACAGCCACCGTGTTCGTCACTGTCCTGGATGTGAATGACAACCGGCCCATCTTTCTGCAGAGC AGCTATGAGGCCAGCGTCCCTGAGGACATCCCTGAAGGCCACAGCATCTTGCAGCTGAAAGCCACGGACGCAGATGAGGGCGAGTTTGGG CGTGTGTGGTACCGCATCCTCCATGGTAACCATGGCAACAACTTCCGGATCCATGTCAGCAATGGGCTCCTGATGCGAGGGCCCCGGCCC CTGGACCGGGAGCGGAACTCATCCCACGTGCTGATAGTGGAGGCCTACAACCACGACCTGGGCCCCATGCGGAGCTCCGTCAGGGTGATT GTGTACGTGGAGGACATCAACGATGAGGCCCCCGTGTTCACACAGCAGCAGTACAGCCGTCTGGGGCTTCGAGAGACCGCAGGCATTGGA ACGTCAGTCATCGTGGTCCAAGCCACAGACCGAGACTCTGGGGATGGTGGCCTGGTGAACTACCGCATCCTGTCGGGCGCAGAGGGGAAG TTTGAGATTGACGAGAGCACAGGGCTTATCATCACCGTGAATTACCTGGACTACGAGACCAAGACCAGCTACATGATGAATGTGTCGGCC ACTGACCAGGCCCCGCCCTTCAACCAGGGCTTCTGCAGCGTCTACATCACTCTGCTCAACGAGCTGGACGAGGCCGTGCAGTTCTCCAAT GCCTCATACGAGGCTGCCATCCTGGAGAATCTGGCACTGGGTACTGAGATTGTGCGGGTCCAGGCCTACTCCATCGACAACCTCAACCAA ATCACGTACCGCTTCAACGCCTACACCAGCACCCAGGCCAAAGCCCTCTTCAAGATAGACGCCATCACGGGTGTGATCACAGTCCAGGGC CTGGTGGACCGTGAGAAGGGCGACTTCTATACCTTGACAGTGGTGGCAGATGACGGCGGCCCCAAGGTGGACTCCACCGTGAAGGTCTAC ATCACTGTGCTGGACGAGAATGACAACAGCCCCCGGTTTGACTTCACCTCCGACTCGGCGGTCAGCATACCCGAGGACTGCCCTGTGGGC CAGCGAGTGGCTACTGTCAAGGCCTGGGACCCTGATGCTGGCAGCAATGGGCAGGTGGTCTTCTCCCTGGCCTCTGGCAACATCGCGGGG GCCTTTGAGATCGTCACCACCAATGACTCCATTGGCGAAGTGTTTGTGGCCAGGCCCCTGGACAGAGAAGAGCTGGATCACTACATCCTC CAGGTTGTGGCTTCTGACCGAGGCACCCCTCCACGGAAGAAGGACCACATCCTGCAGGTGACCATCCTGGACATCAATGACAACCCTCCA GTCATCGAGAGCCCCTTTGGATACAATGTCAGTGTGAATGAGAACGTGGGTGGAGGTACTGCTGTGGTCCAGGTGAGAGCCACTGACCGT GACATCGGGATCAACAGTGTTCTGTCCTACTACATCACCGAGGGCAACAAGGACATGGCCTTCCGCATGGACCGCATCAGCGGTGAGATC GCCACACGGCCTGCCCCGCCTGACCGCGAGCGCCAGAGCTTCTACCACCTGGTGGCCACTGTGGAGGACGAGGGCACCCCAACCCTGTCG TGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGC AGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTT GGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCCTTAGG AGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAA CAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGAC TGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAG AAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAA GCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAAT GAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAG AAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCC CAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGT ACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTC GATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAA CAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAAT CTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCA AGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGT ATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACC AAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCA AGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCT GGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACA TTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCT GGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGA GATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTG TCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAA TTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTT CCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGAT CCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCT GGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAAT GGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAG AAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCT TCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAA TCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCA GAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAG AAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAG GTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCA GAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCT GAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGAC CCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAATCTTGT GCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTGCAGCC AAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGGCCACA AGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAGGAGCT GCACTCAAGGAGAATGTCTGTCAGAATTGTGAAAAATTGGGTGAGCTGCTGTTATGTGAGGCTCAGTGCTGTGGGGCTTTCCACCTGGAG TGCCTTGGATTGACTGAGATGCCAAGAGGAAAATTTATCTGCAATGAATGTCGCACAGGAATCCATACCTGTTTTGTATGTAAGCAGAGT GGGGAAGATGTTAAAAGGTGCCTTCTACCCTTGTGTGGAAAGTTTTACCATGAAGAGTGTGTCCAGAAGTACCCACCCACTGTTATGCAG AACAAGGGCTTCCGGTGCTCCCTCCACATCTGTATAACCTGTCATGCTGCTAATCCAGCCAATGTTTCTGCATCTAAAGGTCGGTTGATG CGCTGTGTCCGCTGTCCTGTGGCATACCACGCCAATGACTTTTGCCTGGCTGCTGGGTCAAAGATCCTTGCATCTAATAGTATCATCTGC CCTAATCACTTTACCCCTAGGCGGGGCTGCCGAAATCATGAGCATGTTAATGTTAGCTGGTGCTTTGTGTGCTCAGAAGGAGGCAGCCTT CTGTGCTGTGATTCTTGCCCTGCTGCTTTTCATCGTGAATGCCTGAACATTGATATCCCTGAAGGAAACTGGTATTGCAATGACTGTAAA GCAGGCAAAAAGCCACACTACAGGGAGATTGTCTGGGTAAAAGTTGGACGATACAGGTGGTGGCCAGCTGAGATCTGCCATCCTCGAGCT GTTCCTTCCAACATTGATAAGATGAGACATGATGTGGGAGAGTTCCCAGTCCTCTTTTTTGGATCTAATGACTATTTGTGGACTCACCAG GCCCGAGTCTTCCCTTACATGGAGGGTGACGTGAGCAGCAAGGATAAGATGGGCAAAGGAGTGGATGGGACATATAAAAAAGCTCTTCAG GAAGCTGCAGCAAGGTTTGAGGAATTAAAGGCCCAAAAAGAGCTAAGACAGCTGCAGGAAGACCGAAAGAATGACAAGAAGCCACCACCT TATAAACATATAAAGGTAAACCGTCCTATTGGCAGGGTACAGATCTTCACTGCAGACTTATCTGAAATACCCCGTTGCAACTGTAAAGCT ACTGATGAGAACCCCTGTGGGATAGACTCTGAATGCATCAACCGCATGCTGCTCTATGAGTGCCACCCCACAGTGTGTCCTGCCGGAGGG CGCTGTCAAAACCAGTGCTTTTCCAAGCGCCAATATCCAGAGGTTGAAATTTTCCGCACATTACAGCGGGGTTGGGGTCTACGGACAAAA ACAGATATTAAAAAGGGTGAATTTGTGAATGAGTATGTGGGTGAGCTTATAGATGAAGAAGAATGCAGAGCTCGAATTCGCTATGCTCAA GAACATGATATCACTAATTTCTATATGCTCACCCTAGACAAAGACCGAATCATTGATGCTGGTCCCAAAGGAAACTATGCTCGGTTCATG AATCATTGCTGCCAGCCCAACTGTGAAACACAGAAGTGGTCTGTGAATGGAGATACCCGTGTAGGCCTTTTTGCACTAAGTGACATTAAA GCAGGCACTGAACTTACCTTCAACTACAACCTAGAATGTCTTGGGAATGGAAAGACTGTTTGCAAATGTGGAGCCCCGAACTGCAGTGGC TTCTTGGGTGTAAGGCCAAAGAATCAACCCATTGCCACGGAAGAAAAGTCAAAGAAATTCAAGAAGAAGCAACAGGGAAAGCGCAGGACC CAGGGTGAAATCACAAAGGAGCGAGAAGATGAGTGTTTTAGTTGTGGGGATGCTGGCCAGCTCGTCTCCTGCAAGAAACCAGGCTGCCCA AAAGTTTACCACGCAGACTGTCTCAATCTGACCAAGCGACCAGCAGGGAAATGGGAATGTCCGTGGCATCAGTGTGACATCTGCGGGAAG GAAGCAGCCTCCTTCTGTGAGATGTGCCCCAGCTCCTTTTGTAAGCAGCATCGAGAAGGGATGCTTTTCATTTCCAAACTGGATGGGCGT CTGTCTTGTACTGAGCATGACCCCTGTGGGCCCAATCCTCTGGAACCTGGGGAGATCCGTGAGTATGTGCCTCCCCCAGTACCGCTGCCT CCAGGGCCAAGCACTCACCTGGCAGAGCAATCAACAGGAATGGCTGCTCAGGCACCCAAAATGTCAGATAAACCTCCTGCTGACACCAAC CAGATGCTGTCGCTCTCCAAAAAAGCTCTGGCAGGGACTTGTCAGAGGCCATTGCTACCTGAAAGACCTCTTGAGAGAACTGACTCCAGG CCCCAGCCTTTAGATAAGGTCAGAGACCTCGCTGGGTCAGGGACCAAATCCCAATCCTTGGTTTCCAGCCAGAGGCCACTGGACAGGCCA CCAGCAGTGGCAGGACCAAGACCCCAGCTAAGCGACAAACCCTCTCCAGTGACCAGCCCAAGCTCCTCACCCTCAGTCAGGTCCCAACCA CTGGAAAGACCTCTGGGGACGGCTGACCCAAGGCTGGATAAATCCATAGGTGCTGCCAGCCCAAGGCCCCAGTCACTGGAGAAAACCTCA GTTCCCACTGGCCTGAGACTTCCGCCGCCAGACAGACTGCTCATTACTAGCAGTCCCAAACCCCAGACTTCAGACAGGCCTACTGACAAA CCCCATGCCTCTTTGTCCCAGAGACTCCCACCTCCTGAGAAAGTACTATCAGCTGTGGTCCAGACCCTTGTAGCTAAAGAAAAAGCACTG AGGCCTGTGGACCAGAATACTCAGTCAAAAAATAGAGCTGCTTTGGTGATGGATCTCATAGACCTAACTCCTCGCCAGAAGGAGCGGGCA GCTTCACCTCATCAGGTCACACCACAGGCTGATGAGAAGATGCCAGTGTTGGAGTCAAGTTCATGGCCTGCCAGCAAAGGTCTGGGGCAT ATGCCGAGAGCTGTTGAGAAAGGCTGTGTGTCAGATCCTCTTCAGACATCTGGGAAAGCAGCAGCCCCTTCAGAGGACCCCTGGCAAGCT GTTAAATCACTCACCCAGGCCAGACTTCTTTCTCAGCCTCCTGCCAAGGCCTTTTTATATGAGCCAACAACTCAGGCCTCAGGAAGAGCT TCTGCAGGGGCTGAGCAGACCCCAGGGCCTCTTAGCCAATCCCCGGGCCTGGTGAAGCAGGCGAAGCAGATGGTCGGAGGCCAGCAACTA CCTGCACTTGCCGCCAAGAGTGGGCAATCTTTTAGGTCTCTCGGGAAGGCCCCAGCCTCCCTCCCCACTGAAGAAAAGAAGTTGGTAACC ACAGAGCAAAGTCCCTGGGCCCTGGGAAAAGCCTCATCACGGGCAGGGCTCTGGCCCATAGTGGCTGGACAGACACTGGCACAGTCTTGC TGGTCTGCTGGGAGCACACAGACATTGGCACAGACTTGCTGGTCTCTTGGAAGAGGGCAAGACCCCAAACCAGAGCAAAATACACTTCCA >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000347982_chr5_176618885_+_12024nt ATGGGGCGCCATGTTGCCACCAGCTGCCACGTGGCCTGGCTTTTGGTGCTGATCTCTGGATGCTGGGGCCAGGTGAACCGGCTGCCCTTC TTCACCAACCACTTCTTTGATACATACCTGCTGATCAGCGAGGACACGCCTGTGGGTTCTTCTGTGACCCAGTTGCTGGCCCAAGACATG GACAATGACCCCCTGGTGTTTGGCGTGTCTGGGGAGGAGGCCTCTCGCTTCTTTGCAGTGGAGCCTGACACTGGCGTGGTGTGGCTCCGG CAGCCACTGGACAGAGAGACCAAGTCAGAGTTCACCGTGGAGTTCTCTGTCAGCGACCACCAGGGGGTGATCACACGGAAGGTGAACATC CAGGTTGGGGATGTGAATGACAACGCGCCCACATTTCACAATCAGCCCTACAGCGTCCGCATCCCTGAGGTAGGAGCCACTGGGAATACA CCAGTGGGGACGCCCATCTTCATCGTGAATGCCACAGACCCCGACTTGGGGGCAGGGGGCAGCGTCCTCTACTCCTTCCAGCCCCCCTCC CAATTCTTCGCCATTGACAGCGCCCGCGGTATCGTCACAGTGATCCGGGAGCTGGACTACGAGACCACACAGGCCTACCAGCTCACGGTC AACGCCACAGATCAAGACAAGACCAGGCCTCTGTCCACCCTGGCCAACTTGGCCATCATCATCACAGATGTCCAGGACATGGACCCCATC TTCATCAACCTGCCTTACAGCACCAACATCTACGAGCATTCTCCTCCGGGCACGACGGTGCGCATCATCACCGCCATAGACCAGGATAAA GGACGTCCCCGGGGCATTGGCTACACCATCGTTTCAGGGAATACCAACAGCATCTTTGCCCTGGACTACATCAGCGGAGTGCTGACCTTG AATGGCCTGCTGGACCGGGAGAACCCCCTGTACAGCCATGGCTTCATCCTGACTGTGAAGGGCACGGAGCTGAACGATGACCGCACCCCA TCTGACGCTACAGTCACCACGACCTTCAATATCCTGGTTATTGACATCAATGACAATGCCCCGGAGTTCAACAGCTCCGAGTACAGCGTG GCCATCACTGAGCTGGCACAGGTCGGCTTTGCCCTTCCACTCTTCATCCAGGTGGTGGACAAGGATGAGAATTTGGGCCTGAACAGCATG TTTGAGGTGTACTTGGTGGGGAACAACTCCCACCACTTCATCATCTCCCCGACCTCCGTCCAGGGGAAGGCGGACATTCGTATTCGGGTG GCCATCCCACTGGACTACGAGACCGTGGACCGCTACGACTTTGATCTCTTTGCCAATGAGAGTGTGCCTGACCATGTGGGCTATGCCAAG GTGAAGATCACTCTCATCAATGAAAATGACAACCGGCCCATCTTCAGCCAGCCACTGTACAACATCAGCCTGTACGAGAACGTCACCGTG GGGACCTCTGTGCTGACAGTCCTGGCAACTGACAATGATGCAGGCACCTTTGGGGAAGTCAGCTACTTCTTCAGTGATGACCCTGACAGG TTCTCGCTGGACAAGGACACGGGACTCATCATGCTGATTGCCAGGCTGGACTATGAGCTCATCCAGCGCTTCACCCTGACGATCATTGCC CGGGACGGGGGCGGCGAGGAGACCACAGGCCGGGTCAGGATCAATGTGTTGGATGTCAACGACAACGTGCCCACCTTCCAGAAGGATGCC TACGTGGGTGCTCTGCGGGAGAACGAGCCTTCTGTCACACAGCTGGTGCGGCTCCGGGCAACAGATGAAGACTCCCCTCCCAACAACCAG ATCACCTACAGCATTGTCAGTGCATCTGCCTTTGGCAGCTACTTCGACATCAGCCTGTACGAGGGCTATGGAGTGATCAGCGTCAGTCGC CCCCTGGATTATGAACAGATATCCAATGGGCTGATTTATCTGACGGTCATGGCCATGGATGCTGGCAACCCCCCTCTCAACAGCACCGTC CCTGTCACCATCGAGGTGTTTGATGAGAATGACAACCCTCCCACCTTCAGCAAGCCCGCCTACTTCGTCTCCGTGGTGGAGAACATCATG GCAGGAGCCACGGTGCTGTTCCTGAATGCCACAGACCTGGACCGCTCCCGGGAGTACGGCCAGGAGTCCATCATCTACTCCTTGGAAGGC TCCACCCAGTTTCGGATCAATGCCCGCTCAGGGGAAATCACCACCACGTCTCTGCTTGACCGAGAGACCAAGTCTGAATACATCCTCATC GTTCGCGCAGTGGACGGGGGTGTGGGCCACAACCAGAAAACTGGCATCGCCACCGTAAACATCACCCTCCTGGACATCAATGACAACCAC CCCACGTGGAAGGACGCACCCTACTACATCAACCTGGTGGAGATGACCCCTCCAGACTCTGATGTGACCACGGTGGTGGCTGTTGACCCA GACCTGGGGGAGAATGGCACCCTGGTGTACAGCATCCAGCCACCCAACAAGTTCTACAGCCTCAACAGCACCACGGGCAAGATCCGCACC ACCCACGCCATGCTGGACCGGGAGAACCCCGACCCCCATGAGGCCGAGCTGATGCGCAAAATCGTCGTCTCTGTTACTGACTGTGGCAGG CCCCCTCTGAAAGCCACCAGCAGTGCCACAGTGTTTGTGAACCTCTTGGATCTCAATGACAATGACCCCACCTTTCAGAACCTGCCTTTT GTGGCCGAGGTGCTTGAAGGCATCCCGGCGGGGGTCTCCATCTACCAAGTGGTGGCCATCGACCTCGATGAGGGCCTGAACGGCCTGGTG TCCTACCGCATGCCGGTGGGCATGCCCCGCATGGACTTCCTCATCAACAGCAGCAGCGGCGTGGTGGTCACCACCACCGAGCTGGACCGC GAGCGCATCGCGGAGTACCAGCTGCGGGTGGTGGCCAGTGATGCAGGCACGCCCACCAAGAGCTCCACCAGCACGCTCACCATCCATGTG CTGGATGTGAACGACGAGACGCCCACCTTCTTCCCGGCCGTGTACAATGTGTCTGTGTCCGAGGACGTGCCACGCGAGTTCCGGGTGGTC TGGCTGAACTGCACGGACAACGACGTGGGCCTCAATGCAGAGCTCAGCTACTTCATCACAGGTGGCAACGTGGATGGGAAGTTCAGCGTG GGTTACCGCGATGCCGTTGTGAGAACCGTGGTGGGCCTGGACCGGGAGACCACAGCCGCCTACATGCTCATCCTGGAGGCCATCGACAAC GGCCCTGTAGGGAAGCGACACACGGGCACAGCCACCGTGTTCGTCACTGTCCTGGATGTGAATGACAACCGGCCCATCTTTCTGCAGAGC AGCTATGAGGCCAGCGTCCCTGAGGACATCCCTGAAGGCCACAGCATCTTGCAGCTGAAAGCCACGGACGCAGATGAGGGCGAGTTTGGG CGTGTGTGGTACCGCATCCTCCATGGTAACCATGGCAACAACTTCCGGATCCATGTCAGCAATGGGCTCCTGATGCGAGGGCCCCGGCCC CTGGACCGGGAGCGGAACTCATCCCACGTGCTGATAGTGGAGGCCTACAACCACGACCTGGGCCCCATGCGGAGCTCCGTCAGGGTGATT GTGTACGTGGAGGACATCAACGATGAGGCCCCCGTGTTCACACAGCAGCAGTACAGCCGTCTGGGGCTTCGAGAGACCGCAGGCATTGGA ACGTCAGTCATCGTGGTCCAAGCCACAGACCGAGACTCTGGGGATGGTGGCCTGGTGAACTACCGCATCCTGTCGGGCGCAGAGGGGAAG TTTGAGATTGACGAGAGCACAGGGCTTATCATCACCGTGAATTACCTGGACTACGAGACCAAGACCAGCTACATGATGAATGTGTCGGCC ACTGACCAGGCCCCGCCCTTCAACCAGGGCTTCTGCAGCGTCTACATCACTCTGCTCAACGAGCTGGACGAGGCCGTGCAGTTCTCCAAT GCCTCATACGAGGCTGCCATCCTGGAGAATCTGGCACTGGGTACTGAGATTGTGCGGGTCCAGGCCTACTCCATCGACAACCTCAACCAA ATCACGTACCGCTTCAACGCCTACACCAGCACCCAGGCCAAAGCCCTCTTCAAGATAGACGCCATCACGGGTGTGATCACAGTCCAGGGC CTGGTGGACCGTGAGAAGGGCGACTTCTATACCTTGACAGTGGTGGCAGATGACGGCGGCCCCAAGGTGGACTCCACCGTGAAGGTCTAC ATCACTGTGCTGGACGAGAATGACAACAGCCCCCGGTTTGACTTCACCTCCGACTCGGCGGTCAGCATACCCGAGGACTGCCCTGTGGGC CAGCGAGTGGCTACTGTCAAGGCCTGGGACCCTGATGCTGGCAGCAATGGGCAGGTGGTCTTCTCCCTGGCCTCTGGCAACATCGCGGGG GCCTTTGAGATCGTCACCACCAATGACTCCATTGGCGAAGTGTTTGTGGCCAGGCCCCTGGACAGAGAAGAGCTGGATCACTACATCCTC CAGGTTGTGGCTTCTGACCGAGGCACCCCTCCACGGAAGAAGGACCACATCCTGCAGGTGACCATCCTGGACATCAATGACAACCCTCCA GTCATCGAGAGCCCCTTTGGATACAATGTCAGTGTGAATGAGAACGTGGGTGGAGGTACTGCTGTGGTCCAGGTGAGAGCCACTGACCGT GACATCGGGATCAACAGTGTTCTGTCCTACTACATCACCGAGGGCAACAAGGACATGGCCTTCCGCATGGACCGCATCAGCGGTGAGATC GCCACACGGCCTGCCCCGCCTGACCGCGAGCGCCAGAGCTTCTACCACCTGGTGGCCACTGTGGAGGACGAGGGCACCCCAACCCTGTCG TGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGC AGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTT GGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCCTTAGG AGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAA CAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGAC TGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAG AAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAA GCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAAT GAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAG AAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCC CAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGT ACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTC GATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAA CAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAAT CTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCA AGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGT ATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACC AAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCA AGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCT GGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACA TTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCT GGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGA GATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTG TCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAA TTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTT CCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGAT CCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCT GGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAAT GGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAG AAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCT TCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAA TCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCA GAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAG AAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAG GTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCA GAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCT GAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGAC CCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAATCTTGT GCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTGCAGCC AAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGGCCACA AGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAGGAGCT GCACTCAAGGAGAATGTCTGTCAGAATTGTGAAAAATTGGGTGAGCTGCTGTTATGTGAGGCTCAGTGCTGTGGGGCTTTCCACCTGGAG TGCCTTGGATTGACTGAGATGCCAAGAGGAAAATTTATCTGCAATGAATGTCGCACAGGAATCCATACCTGTTTTGTATGTAAGCAGAGT GGGGAAGATGTTAAAAGGTGCCTTCTACCCTTGTGTGGAAAGTTTTACCATGAAGAGTGTGTCCAGAAGTACCCACCCACTGTTATGCAG AACAAGGGCTTCCGGTGCTCCCTCCACATCTGTATAACCTGTCATGCTGCTAATCCAGCCAATGTTTCTGCATCTAAAGGTCGGTTGATG CGCTGTGTCCGCTGTCCTGTGGCATACCACGCCAATGACTTTTGCCTGGCTGCTGGGTCAAAGATCCTTGCATCTAATAGTATCATCTGC CCTAATCACTTTACCCCTAGGCGGGGCTGCCGAAATCATGAGCATGTTAATGTTAGCTGGTGCTTTGTGTGCTCAGAAGGAGGCAGCCTT CTGTGCTGTGATTCTTGCCCTGCTGCTTTTCATCGTGAATGCCTGAACATTGATATCCCTGAAGGAAACTGGTATTGCAATGACTGTAAA GCAGGCAAAAAGCCACACTACAGGGAGATTGTCTGGGTAAAAGTTGGACGATACAGGTGGTGGCCAGCTGAGATCTGCCATCCTCGAGCT GTTCCTTCCAACATTGATAAGATGAGACATGATGTGGGAGAGTTCCCAGTCCTCTTTTTTGGATCTAATGACTATTTGTGGACTCACCAG GCCCGAGTCTTCCCTTACATGGAGGGTGACGTGAGCAGCAAGGATAAGATGGGCAAAGGAGTGGATGGGACATATAAAAAAGCTCTTCAG GAAGCTGCAGCAAGGTTTGAGGAATTAAAGGCCCAAAAAGAGCTAAGACAGCTGCAGGAAGACCGAAAGAATGACAAGAAGCCACCACCT TATAAACATATAAAGGTAAACCGTCCTATTGGCAGGGTACAGATCTTCACTGCAGACTTATCTGAAATACCCCGTTGCAACTGTAAAGCT ACTGATGAGAACCCCTGTGGGATAGACTCTGAATGCATCAACCGCATGCTGCTCTATGAGTGCCACCCCACAGTGTGTCCTGCCGGAGGG CGCTGTCAAAACCAGTGCTTTTCCAAGCGCCAATATCCAGAGGTTGAAATTTTCCGCACATTACAGCGGGGTTGGGGTCTACGGACAAAA ACAGATATTAAAAAGGGTGAATTTGTGAATGAGTATGTGGGTGAGCTTATAGATGAAGAAGAATGCAGAGCTCGAATTCGCTATGCTCAA GAACATGATATCACTAATTTCTATATGCTCACCCTAGACAAAGACCGAATCATTGATGCTGGTCCCAAAGGAAACTATGCTCGGTTCATG AATCATTGCTGCCAGCCCAACTGTGAAACACAGAAGTGGTCTGTGAATGGAGATACCCGTGTAGGCCTTTTTGCACTAAGTGACATTAAA GCAGGCACTGAACTTACCTTCAACTACAACCTAGAATGTCTTGGGAATGGAAAGACTGTTTGCAAATGTGGAGCCCCGAACTGCAGTGGC TTCTTGGGTGTAAGGCCAAAGAATCAACCCATTGCCACGGAAGAAAAGTCAAAGAAATTCAAGAAGAAGCAACAGGGAAAGCGCAGGACC CAGGGTGAAATCACAAAGGAGCGAGAAGATGAGTGTTTTAGTTGTGGGGATGCTGGCCAGCTCGTCTCCTGCAAGAAACCAGGCTGCCCA AAAGTTTACCACGCAGACTGTCTCAATCTGACCAAGCGACCAGCAGGGAAATGGGAATGTCCGTGGCATCAGTGTGACATCTGCGGGAAG GAAGCAGCCTCCTTCTGTGAGATGTGCCCCAGCTCCTTTTGTAAGCAGCATCGAGAAGGGATGCTTTTCATTTCCAAACTGGATGGGCGT CTGTCTTGTACTGAGCATGACCCCTGTGGGCCCAATCCTCTGGAACCTGGGGAGATCCGTGAGTATGTGCCTCCCCCAGTACCGCTGCCT CCAGGGCCAAGCACTCACCTGGCAGAGCAATCAACAGGAATGGCTGCTCAGGCACCCAAAATGTCAGATAAACCTCCTGCTGACACCAAC CAGATGCTGTCGCTCTCCAAAAAAGCTCTGGCAGGGACTTGTCAGAGGCCATTGCTACCTGAAAGACCTCTTGAGAGAACTGACTCCAGG CCCCAGCCTTTAGATAAGGTCAGAGACCTCGCTGGGTCAGGGACCAAATCCCAATCCTTGGTTTCCAGCCAGAGGCCACTGGACAGGCCA CCAGCAGTGGCAGGACCAAGACCCCAGCTAAGCGACAAACCCTCTCCAGTGACCAGCCCAAGCTCCTCACCCTCAGTCAGGTCCCAACCA CTGGAAAGACCTCTGGGGACGGCTGACCCAAGGCTGGATAAATCCATAGGTGCTGCCAGCCCAAGGCCCCAGTCACTGGAGAAAACCTCA GTTCCCACTGGCCTGAGACTTCCGCCGCCAGACAGACTGCTCATTACTAGCAGTCCCAAACCCCAGACTTCAGACAGGCCTACTGACAAA CCCCATGCCTCTTTGTCCCAGAGACTCCCACCTCCTGAGAAAGTACTATCAGCTGTGGTCCAGACCCTTGTAGCTAAAGAAAAAGCACTG AGGCCTGTGGACCAGAATACTCAGTCAAAAAATAGAGCTGCTTTGGTGATGGATCTCATAGACCTAACTCCTCGCCAGAAGGAGCGGGCA GCTTCACCTCATCAGGTCACACCACAGGCTGATGAGAAGATGCCAGTGTTGGAGTCAAGTTCATGGCCTGCCAGCAAAGGTCTGGGGCAT ATGCCGAGAGCTGTTGAGAAAGGCTGTGTGTCAGATCCTCTTCAGACATCTGGGAAAGCAGCAGCCCCTTCAGAGGACCCCTGGCAAGCT GTTAAATCACTCACCCAGGCCAGACTTCTTTCTCAGCCTCCTGCCAAGGCCTTTTTATATGAGCCAACAACTCAGGCCTCAGGAAGAGCT TCTGCAGGGGCTGAGCAGACCCCAGGGCCTCTTAGCCAATCCCCGGGCCTGGTGAAGCAGGCGAAGCAGATGGTCGGAGGCCAGCAACTA CCTGCACTTGCCGCCAAGAGTGGGCAATCTTTTAGGTCTCTCGGGAAGGCCCCAGCCTCCCTCCCCACTGAAGAAAAGAAGTTGGTAACC ACAGAGCAAAGTCCCTGGGCCCTGGGAAAAGCCTCATCACGGGCAGGGCTCTGGCCCATAGTGGCTGGACAGACACTGGCACAGTCTTGC TGGTCTGCTGGGAGCACACAGACATTGGCACAGACTTGCTGGTCTCTTGGAAGAGGGCAAGACCCCAAACCAGAGCAAAATACACTTCCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000354179_chr5_176618885_+_16780nt GAGCCATGGGGCGCCATGTTGCCACCAGCTGCCACGTGGCCTGGCTTTTGGTGCTGATCTCTGGATGCTGGGGCCAGGTGAACCGGCTGC CCTTCTTCACCAACCACTTCTTTGATACATACCTGCTGATCAGCGAGGACACGCCTGTGGGTTCTTCTGTGACCCAGTTGCTGGCCCAAG ACATGGACAATGACCCCCTGGTGTTTGGCGTGTCTGGGGAGGAGGCCTCTCGCTTCTTTGCAGTGGAGCCTGACACTGGCGTGGTGTGGC TCCGGCAGCCACTGGACAGAGAGACCAAGTCAGAGTTCACCGTGGAGTTCTCTGTCAGCGACCACCAGGGGGTGATCACACGGAAGGTGA ACATCCAGGTTGGGGATGTGAATGACAACGCGCCCACATTTCACAATCAGCCCTACAGCGTCCGCATCCCTGAGGTAGGAGCCACTGGGA ATACACCAGTGGGGACGCCCATCTTCATCGTGAATGCCACAGACCCCGACTTGGGGGCAGGGGGCAGCGTCCTCTACTCCTTCCAGCCCC CCTCCCAATTCTTCGCCATTGACAGCGCCCGCGGTATCGTCACAGTGATCCGGGAGCTGGACTACGAGACCACACAGGCCTACCAGCTCA CGGTCAACGCCACAGATCAAGACAAGACCAGGCCTCTGTCCACCCTGGCCAACTTGGCCATCATCATCACAGATGTCCAGGACATGGACC CCATCTTCATCAACCTGCCTTACAGCACCAACATCTACGAGCATTCTCCTCCGGGCACGACGGTGCGCATCATCACCGCCATAGACCAGG ATAAAGGACGTCCCCGGGGCATTGGCTACACCATCGTTTCAGGGAATACCAACAGCATCTTTGCCCTGGACTACATCAGCGGAGTGCTGA CCTTGAATGGCCTGCTGGACCGGGAGAACCCCCTGTACAGCCATGGCTTCATCCTGACTGTGAAGGGCACGGAGCTGAACGATGACCGCA CCCCATCTGACGCTACAGTCACCACGACCTTCAATATCCTGGTTATTGACATCAATGACAATGCCCCGGAGTTCAACAGCTCCGAGTACA GCGTGGCCATCACTGAGCTGGCACAGGTCGGCTTTGCCCTTCCACTCTTCATCCAGGTGGTGGACAAGGATGAGAATTTGGGCCTGAACA GCATGTTTGAGGTGTACTTGGTGGGGAACAACTCCCACCACTTCATCATCTCCCCGACCTCCGTCCAGGGGAAGGCGGACATTCGTATTC GGGTGGCCATCCCACTGGACTACGAGACCGTGGACCGCTACGACTTTGATCTCTTTGCCAATGAGAGTGTGCCTGACCATGTGGGCTATG CCAAGGTGAAGATCACTCTCATCAATGAAAATGACAACCGGCCCATCTTCAGCCAGCCACTGTACAACATCAGCCTGTACGAGAACGTCA CCGTGGGGACCTCTGTGCTGACAGTCCTGGCAACTGACAATGATGCAGGCACCTTTGGGGAAGTCAGCTACTTCTTCAGTGATGACCCTG ACAGGTTCTCGCTGGACAAGGACACGGGACTCATCATGCTGATTGCCAGGCTGGACTATGAGCTCATCCAGCGCTTCACCCTGACGATCA TTGCCCGGGACGGGGGCGGCGAGGAGACCACAGGCCGGGTCAGGATCAATGTGTTGGATGTCAACGACAACGTGCCCACCTTCCAGAAGG ATGCCTACGTGGGTGCTCTGCGGGAGAACGAGCCTTCTGTCACACAGCTGGTGCGGCTCCGGGCAACAGATGAAGACTCCCCTCCCAACA ACCAGATCACCTACAGCATTGTCAGTGCATCTGCCTTTGGCAGCTACTTCGACATCAGCCTGTACGAGGGCTATGGAGTGATCAGCGTCA GTCGCCCCCTGGATTATGAACAGATATCCAATGGGCTGATTTATCTGACGGTCATGGCCATGGATGCTGGCAACCCCCCTCTCAACAGCA CCGTCCCTGTCACCATCGAGGTGTTTGATGAGAATGACAACCCTCCCACCTTCAGCAAGCCCGCCTACTTCGTCTCCGTGGTGGAGAACA TCATGGCAGGAGCCACGGTGCTGTTCCTGAATGCCACAGACCTGGACCGCTCCCGGGAGTACGGCCAGGAGTCCATCATCTACTCCTTGG AAGGCTCCACCCAGTTTCGGATCAATGCCCGCTCAGGGGAAATCACCACCACGTCTCTGCTTGACCGAGAGACCAAGTCTGAATACATCC TCATCGTTCGCGCAGTGGACGGGGGTGTGGGCCACAACCAGAAAACTGGCATCGCCACCGTAAACATCACCCTCCTGGACATCAATGACA ACCACCCCACGTGGAAGGACGCACCCTACTACATCAACCTGGTGGAGATGACCCCTCCAGACTCTGATGTGACCACGGTGGTGGCTGTTG ACCCAGACCTGGGGGAGAATGGCACCCTGGTGTACAGCATCCAGCCACCCAACAAGTTCTACAGCCTCAACAGCACCACGGGCAAGATCC GCACCACCCACGCCATGCTGGACCGGGAGAACCCCGACCCCCATGAGGCCGAGCTGATGCGCAAAATCGTCGTCTCTGTTACTGACTGTG GCAGGCCCCCTCTGAAAGCCACCAGCAGTGCCACAGTGTTTGTGAACCTCTTGGATCTCAATGACAATGACCCCACCTTTCAGAACCTGC CTTTTGTGGCCGAGGTGCTTGAAGGCATCCCGGCGGGGGTCTCCATCTACCAAGTGGTGGCCATCGACCTCGATGAGGGCCTGAACGGCC TGGTGTCCTACCGCATGCCGGTGGGCATGCCCCGCATGGACTTCCTCATCAACAGCAGCAGCGGCGTGGTGGTCACCACCACCGAGCTGG ACCGCGAGCGCATCGCGGAGTACCAGCTGCGGGTGGTGGCCAGTGATGCAGGCACGCCCACCAAGAGCTCCACCAGCACGCTCACCATCC ATGTGCTGGATGTGAACGACGAGACGCCCACCTTCTTCCCGGCCGTGTACAATGTGTCTGTGTCCGAGGACGTGCCACGCGAGTTCCGGG TGGTCTGGCTGAACTGCACGGACAACGACGTGGGCCTCAATGCAGAGCTCAGCTACTTCATCACAGGTGGCAACGTGGATGGGAAGTTCA GCGTGGGTTACCGCGATGCCGTTGTGAGAACCGTGGTGGGCCTGGACCGGGAGACCACAGCCGCCTACATGCTCATCCTGGAGGCCATCG ACAACGGCCCTGTAGGGAAGCGACACACGGGCACAGCCACCGTGTTCGTCACTGTCCTGGATGTGAATGACAACCGGCCCATCTTTCTGC AGAGCAGCTATGAGGCCAGCGTCCCTGAGGACATCCCTGAAGGCCACAGCATCTTGCAGCTGAAAGCCACGGACGCAGATGAGGGCGAGT TTGGGCGTGTGTGGTACCGCATCCTCCATGGTAACCATGGCAACAACTTCCGGATCCATGTCAGCAATGGGCTCCTGATGCGAGGGCCCC GGCCCCTGGACCGGGAGCGGAACTCATCCCACGTGCTGATAGTGGAGGCCTACAACCACGACCTGGGCCCCATGCGGAGCTCCGTCAGGG TGATTGTGTACGTGGAGGACATCAACGATGAGGCCCCCGTGTTCACACAGCAGCAGTACAGCCGTCTGGGGCTTCGAGAGACCGCAGGCA TTGGAACGTCAGTCATCGTGGTCCAAGCCACAGACCGAGACTCTGGGGATGGTGGCCTGGTGAACTACCGCATCCTGTCGGGCGCAGAGG GGAAGTTTGAGATTGACGAGAGCACAGGGCTTATCATCACCGTGAATTACCTGGACTACGAGACCAAGACCAGCTACATGATGAATGTGT CGGCCACTGACCAGGCCCCGCCCTTCAACCAGGGCTTCTGCAGCGTCTACATCACTCTGCTCAACGAGCTGGACGAGGCCGTGCAGTTCT CCAATGCCTCATACGAGGCTGCCATCCTGGAGAATCTGGCACTGGGTACTGAGATTGTGCGGGTCCAGGCCTACTCCATCGACAACCTCA ACCAAATCACGTACCGCTTCAACGCCTACACCAGCACCCAGGCCAAAGCCCTCTTCAAGATAGACGCCATCACGGGTGTGATCACAGTCC AGGGCCTGGTGGACCGTGAGAAGGGCGACTTCTATACCTTGACAGTGGTGGCAGATGACGGCGGCCCCAAGGTGGACTCCACCGTGAAGG TCTACATCACTGTGCTGGACGAGAATGACAACAGCCCCCGGTTTGACTTCACCTCCGACTCGGCGGTCAGCATACCCGAGGACTGCCCTG TGGGCCAGCGAGTGGCTACTGTCAAGGCCTGGGACCCTGATGCTGGCAGCAATGGGCAGGTGGTCTTCTCCCTGGCCTCTGGCAACATCG CGGGGGCCTTTGAGATCGTCACCACCAATGACTCCATTGGCGAAGTGTTTGTGGCCAGGCCCCTGGACAGAGAAGAGCTGGATCACTACA TCCTCCAGGTTGTGGCTTCTGACCGAGGCACCCCTCCACGGAAGAAGGACCACATCCTGCAGGTGACCATCCTGGACATCAATGACAACC CTCCAGTCATCGAGAGCCCCTTTGGATACAATGTCAGTGTGAATGAGAACGTGGGTGGAGGTACTGCTGTGGTCCAGGTGAGAGCCACTG ACCGTGACATCGGGATCAACAGTGTTCTGTCCTACTACATCACCGAGGGCAACAAGGACATGGCCTTCCGCATGGACCGCATCAGCGGTG AGATCGCCACACGGCCTGCCCCGCCTGACCGCGAGCGCCAGAGCTTCTACCACCTGGTGGCCACTGTGGAGGACGAGGGCACCCCAACCC TGTCGTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGC CCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGG CTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCC TTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTG CAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTG AAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAG ATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAAT TTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCT CTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTG CAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATA AACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTA TCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATG CTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAG CAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGG TTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGT CATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCC GAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTG ATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGG ATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTG ACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCA GTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGA GTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAA AGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCT TACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCAT CCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATC AGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAG AGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTG ATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAAC TCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTA AAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAA CTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTG ATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGC GGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAAC AAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACA AGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTC AGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTG AGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATT TAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAAT CTTGTGCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTG CAGCCAAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGG CCACAAGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAG GAGCTGCACTCAAGGAGAATGTCTGTCAGAATTGTGAAAAATTGGGTGAGCTGCTGTTATGTGAGGCTCAGTGCTGTGGGGCTTTCCACC TGGAGTGCCTTGGATTGACTGAGATGCCAAGAGGAAAATTTATCTGCAATGAATGTCGCACAGGAATCCATACCTGTTTTGTATGTAAGC AGAGTGGGGAAGATGTTAAAAGGTGCCTTCTACCCTTGTGTGGAAAGTTTTACCATGAAGAGTGTGTCCAGAAGTACCCACCCACTGTTA TGCAGAACAAGGGCTTCCGGTGCTCCCTCCACATCTGTATAACCTGTCATGCTGCTAATCCAGCCAATGTTTCTGCATCTAAAGGTCGGT TGATGCGCTGTGTCCGCTGTCCTGTGGCATACCACGCCAATGACTTTTGCCTGGCTGCTGGGTCAAAGATCCTTGCATCTAATAGTATCA TCTGCCCTAATCACTTTACCCCTAGGCGGGGCTGCCGAAATCATGAGCATGTTAATGTTAGCTGGTGCTTTGTGTGCTCAGAAGGAGGCA GCCTTCTGTGCTGTGATTCTTGCCCTGCTGCTTTTCATCGTGAATGCCTGAACATTGATATCCCTGAAGGAAACTGGTATTGCAATGACT GTAAAGCAGGCAAAAAGCCACACTACAGGGAGATTGTCTGGGTAAAAGTTGGACGATACAGGTGGTGGCCAGCTGAGATCTGCCATCCTC GAGCTGTTCCTTCCAACATTGATAAGATGAGACATGATGTGGGAGAGTTCCCAGTCCTCTTTTTTGGATCTAATGACTATTTGTGGACTC ACCAGGCCCGAGTCTTCCCTTACATGGAGGGTGACGTGAGCAGCAAGGATAAGATGGGCAAAGGAGTGGATGGGACATATAAAAAAGCTC TTCAGGAAGCTGCAGCAAGGTTTGAGGAATTAAAGGCCCAAAAAGAGCTAAGACAGCTGCAGGAAGACCGAAAGAATGACAAGAAGCCAC CACCTTATAAACATATAAAGGTAAACCGTCCTATTGGCAGGGTACAGATCTTCACTGCAGACTTATCTGAAATACCCCGTTGCAACTGTA AAGCTACTGATGAGAACCCCTGTGGGATAGACTCTGAATGCATCAACCGCATGCTGCTCTATGAGTGCCACCCCACAGTGTGTCCTGCCG GAGGGCGCTGTCAAAACCAGTGCTTTTCCAAGCGCCAATATCCAGAGGTTGAAATTTTCCGCACATTACAGCGGGGTTGGGGTCTACGGA CAAAAACAGATATTAAAAAGGGTGAATTTGTGAATGAGTATGTGGGTGAGCTTATAGATGAAGAAGAATGCAGAGCTCGAATTCGCTATG CTCAAGAACATGATATCACTAATTTCTATATGCTCACCCTAGACAAAGACCGAATCATTGATGCTGGTCCCAAAGGAAACTATGCTCGGT TCATGAATCATTGCTGCCAGCCCAACTGTGAAACACAGAAGTGGTCTGTGAATGGAGATACCCGTGTAGGCCTTTTTGCACTAAGTGACA TTAAAGCAGGCACTGAACTTACCTTCAACTACAACCTAGAATGTCTTGGGAATGGAAAGACTGTTTGCAAATGTGGAGCCCCGAACTGCA GTGGCTTCTTGGGTGTAAGGCCAAAGAATCAACCCATTGCCACGGAAGAAAAGTCAAAGAAATTCAAGAAGAAGCAACAGGGAAAGCGCA GGACCCAGGGTGAAATCACAAAGGAGCGAGAAGATGAGTGTTTTAGTTGTGGGGATGCTGGCCAGCTCGTCTCCTGCAAGAAACCAGGCT GCCCAAAAGTTTACCACGCAGACTGTCTCAATCTGACCAAGCGACCAGCAGGGAAATGGGAATGTCCGTGGCATCAGTGTGACATCTGCG GGAAGGAAGCAGCCTCCTTCTGTGAGATGTGCCCCAGCTCCTTTTGTAAGCAGCATCGAGAAGGGATGCTTTTCATTTCCAAACTGGATG GGCGTCTGTCTTGTACTGAGCATGACCCCTGTGGGCCCAATCCTCTGGAACCTGGGGAGATCCGTGAGTATGTGCCTCCCCCAGTACCGC TGCCTCCAGGGCCAAGCACTCACCTGGCAGAGCAATCAACAGGAATGGCTGCTCAGGCACCCAAAATGTCAGATAAACCTCCTGCTGACA CCAACCAGATGCTGTCGCTCTCCAAAAAAGCTCTGGCAGGGACTTGTCAGAGGCCATTGCTACCTGAAAGACCTCTTGAGAGAACTGACT CCAGGCCCCAGCCTTTAGATAAGGTCAGAGACCTCGCTGGGTCAGGGACCAAATCCCAATCCTTGGTTTCCAGCCAGAGGCCACTGGACA GGCCACCAGCAGTGGCAGGACCAAGACCCCAGCTAAGCGACAAACCCTCTCCAGTGACCAGCCCAAGCTCCTCACCCTCAGTCAGGTCCC AACCACTGGAAAGACCTCTGGGGACGGCTGACCCAAGGCTGGATAAATCCATAGGTGCTGCCAGCCCAAGGCCCCAGTCACTGGAGAAAA CCTCAGTTCCCACTGGCCTGAGACTTCCGCCGCCAGACAGACTGCTCATTACTAGCAGTCCCAAACCCCAGACTTCAGACAGGCCTACTG ACAAACCCCATGCCTCTTTGTCCCAGAGACTCCCACCTCCTGAGAAAGTACTATCAGCTGTGGTCCAGACCCTTGTAGCTAAAGAAAAAG CACTGAGGCCTGTGGACCAGAATACTCAGTCAAAAAATAGAGCTGCTTTGGTGATGGATCTCATAGACCTAACTCCTCGCCAGAAGGAGC GGGCAGCTTCACCTCATCAGGTCACACCACAGGCTGATGAGAAGATGCCAGTGTTGGAGTCAAGTTCATGGCCTGCCAGCAAAGGTCTGG GGCATATGCCGAGAGCTGTTGAGAAAGGCTGTGTGTCAGATCCTCTTCAGACATCTGGGAAAGCAGCAGCCCCTTCAGAGGACCCCTGGC AAGCTGTTAAATCACTCACCCAGGCCAGACTTCTTTCTCAGCCTCCTGCCAAGGCCTTTTTATATGAGCCAACAACTCAGGCCTCAGGAA GAGCTTCTGCAGGGGCTGAGCAGACCCCAGGGCCTCTTAGCCAATCCCCGGGCCTGGTGAAGCAGGCGAAGCAGATGGTCGGAGGCCAGC AACTACCTGCACTTGCCGCCAAGAGTGGGCAATCTTTTAGGTCTCTCGGGAAGGCCCCAGCCTCCCTCCCCACTGAAGAAAAGAAGTTGG TAACCACAGAGCAAAGTCCCTGGGCCCTGGGAAAAGCCTCATCACGGGCAGGGCTCTGGCCCATAGTGGCTGGACAGACACTGGCACAGT CTTGCTGGTCTGCTGGGAGCACACAGACATTGGCACAGACTTGCTGGTCTCTTGGAAGAGGGCAAGACCCCAAACCAGAGCAAAATACAC TTCCAGCTCTTAACCAGGCTCCTTCCAGTCACAAGTGTGCAGAATCAGAACAGAAGTAGTACCAATCAATGTCACATGAACAAACAAGCT GCCCCCAGGGTACCATTTGGGGAGGGGAAATCTTTTCTTTCTTTCCCCCTTAAAAAAAAACACATCTGCCCCGAACACTTTCCCACTGTT ATTCTTTCCTCATATCCCAACACTCAGAACTCTTGTGACATTAGCCAGTGGGGGCTTATGGTTGTGTGAACCATGTATGAAAATCCAGTG GGCCCCAACCAAGGAGACAGACAGACTTGGGTCTCTTTCCCCCAACTTTTCCACATGGTCATCGTGAAATAAAAAGTCCACTCTGGAGTC AAGTATGGAATTCAATTCCGCTGGTCAGGTTGGAAGGTATAGGGGCTCTCAAAGCGATTTCCCCAACCAGACAGAGCCCCATTGAGGGCA CCTAGGAACCCTTGGGAGGAAATGGTGTTCTTTCAAATCAGTGGCGATTTCCTGAGCATTCACGTGTTCTAGGCCGGGTGCTAGTCACTG ATGAGAGATACAGGCCTCATCCCTGTGAGCCTGGATTCCAAGGCTTTCAGGAACCTTTGACCAGGAAGTAACAGGAAGTTCTGAGGGGCC CTGGGGCTTTAGACTCATTTTGAAATGTCCTTTGTGGCACCAGAAGTGGTTGTGTTGAGGAAGTGTCTCTTGGCTGCGGTGTGCATGGGT GCGTGTGCATGCGCGCACACTCACAGAGGTCTCCTCTATAGATGCAAGGGTGCTGCATTGAGGCCAGCAAGGCTGTTGGCTGTGGGGTCG CCGCTGCTGCTTTTGTCTGGGCTGTGCAGAGTCTCAAGATCAGTCCTTGGAGGAGCAGGTGGTCAGGGGCAGTCGGGCTCTGTGCGAATG TAGATTTCCAGCAGTGGAAGAAGGCATTTGGCAAGCTTCTCTTTCTTTGCTTTTGTTTCTACCTATTTTTCTCTTTGTACATGAATCCAC CCCATCCCTATTTCCCTAAAACACTCAGGTGCTTTCAGATTTCAGAGCCTCGGGCAGTGGACATAGGGAATCTCTGGCAAGCTCTGAGCT AGACACACCAGCTTCAGGAAGAGTACCAGATCCTGATGGGAAATTTCTTTTCCCCATTCCTTTTCCCTCCTGAGTGGAGGGAGTCCTCTT CTTCGCCTCCCTGAGAATTGCTGTGCTCTGTATTGAGAGCACCTGCCTGCTGACTTAGCTCAAAGGCAAGCCAGAACCCTTCCCTGAAGA CTGGCAAGAGGTGGTGTTTAGAGCAACGTCCAGGCTAAGAGATGACTCCTATTAACTGCTGATTATCTGTTACTGCTGCCCTGAGCTGGG GCCCAAGGGCTGGGAAATCTGTTGGTGCTACCCTGCCCTACCATTCACCCAGCTCACAGACTGCCAACAGGAAGTGCTGTTTGGCTAGTT TCCTCCCACTTGTCTACCCCTCCTTTGTCCTTAGACCAACATGTTTACCTCTCTGCTTTGCCAACTTAGCCAGCAGGCCATCCCCGGCCC TAACGTCTCCTGGCCATTATCTCTTAGTTATGGCTTTCACGCTCTCAATAGGATTCTGTATTTGGTCCCAATTTCCTCAAGTTCTTATTG AGGTTACTCCCATCAATTCCACGGAGGGAACAGTAGTTATTATAGAAGCATTTGCGCTTTATCTAAAGATTAAAAATAGAATCTGCTTTT ATTTCCCAAAGTCTGTCTCTGAGGTTGAGACACTTGAACTCAGGCAGAGGGACGAGGCTGGGCAGGGCTGTCCTGAGTTTAGGGGCCTAT CCCTGCATTTCACTGAGACCTCGGAATCTCCTCTGTGAATTCCACCTGCCTAGTTCTCCCCTTTCATCCTCTCTCTCTTCCCACATCATC AAAGAGGAAAAGCTCTTTGTTCAAAAGGAAGAGAAAACGTAAAGCATCTTATTTTCTTTTAAAAGAATTTTAAACCATGAAAAAGATATT TTTAAAGAAATTCACCGAGAACATTAAAGTTCATTATATTAAGTATTTATCATGTGTGAGAATAATAAATATATAACTGCAGCTAGTAGG TCCCTTTCCCTAATCTTTTAGGTCATATGAGTAGGGTTTGCTTGGTGCCAGTCCTGTGCCCTTTTCTCTCCAGTCATCTGTAGTTGTGAT CAGAAAAAGGTATCTGCACTGCACTGTCAGAGTCTCCTTTCACTATGTTGTGTGTTAAATTACCGTAGCTCTTTGTTTCATGAAATAAAC TGTGAATTTGGGGGGGGCGGGGGGAGGGCGTGCAGGCCATGTAAAAATTTTCCGTGGAGAAGTTTGATTCTAAAGTAGCTTCTCTAAAGT AGGCTTTGGTAGGTAATCAACTTGACAGCAGTCTAGATGTCTCACAGGACAGGAGGGAGTGAGGGAAAGGGGCCATGATTGGCTGCTTTG TGGTTTTATTTTGGTTCTTTCCATTCTCCGCCATTCATTGGAGGCTTCGTTCCAGACCTGCCTGGGAAAACAGCTTCTGAGCCATTTTGG GGAGCAGTTCTTCATCTGAATGGATGGACATCTGGGCTTCCTTCAAGGGCCATTGAATGGGAACTAGAAAACCACTGGAAACTAGAAATT TGAGCTATTGGGCCCACCAGTAGCAGCATGTGATACTAGATGGTTAAAATCATGAAAGCAGTCACTATCCAATTAGAAGCAGAGTCACAA CAACTGTTGGGAAATGTGACTCTTGGAGGAAGGTGGGGAGGGAGTGGCCTTGCCAGCCCTGTGGGACGTCCCCTGAAGTTTGTAATAAGA CCCCTTTTCCAAAGGGATGTGAATTGGAGTGAAAAGGAAATCTTTCATCTTAGAAAACTTCTGGTCCTTAACGCAGGGTGGTATTTGGGT ATGTGCTTGGAAATTGAGATCTCAAGAGTGTTTGCCTTGGAGCCAGCTCCCCAGGAGGCCTTTTCCAGGGACAAGGCAAAAGTTGAAATT CTCCATGGGTAGCTAGAAAGCCAATACATCTAGCCCTGCTAAGTCAGAAAAAGATTATGAAAAATGTTGAAATTTACATTCAAAGCCTCA TTTGCTTATCTTGCTGGAGCCAACCCAGTCTAATAGCAAAATAGCTGTCATTGATACAGAAACATCCTCATTTTTAAATGTCTGCTTTAC CCTGTTACTGAGTTTGAGATGACTTAAATCACTGTGTTGACCCTCTTCTGAACCAAATCTTTAGCATTGATGAAAATAGTTATTTTATTC TTTACATCCTTCACCCCACACTATGGTCAGGGCATGAAACACCCTGTTGATCCCTTCCCAGGCTCGGCACTGTCTGCTCACTGGAGCCGG ACTCCCAGGTTGTAATTCTAATGTTGCCTCATGAGAACAGAATGGCAGAAAGTTTAGTCCTGACAGATTCCCCCATAGGGAGTAATGAGG ACAGCATGAAACTTGGATAGGTTTTACCCTTAGTCCCTATAAGGTGGATTTTACTAAGGTTTTTTAAATGATACTGTCATCCTCTTGGGG TTTATCAGCCAGGTTAGAGGAGCCCAGTGTCCTAACCTCTCTCAGATCATGGCAGAGAAGGAGCTGCCTCCAGCCCCTTTCTTGCTGAGT TTCATTTGAGCAGTTCCATGTGTAGACATTCCAAGTCACTGCTTGGTAGTTGCTGTGGGAGCCTGTCATTGGCTATGGCCAGTTAGTTCT CAGCTGAGCTTCCTAGGGCCAGTGCAACAGGGCCAGAGGCTGCTATAGTGTAAATTGAAATAAGAATAGATCATTGTTTTGTACACACAC ACAATAAAATGTAATGATGGTGCTAATTTCACGGTATAAATAAGCACTGCCAAGGGTTGAGGGACTGGCAGCTCAAGAAACCCGGGTTCC TGTTTGGGAGGAGATTTTATGTAGAAAAGTTTGAGGCTTTGTTAAAAGTGGGGAGAAGGAAGATCCTCAGTGAAGCCTGCACCCAACCCT GGAGTGGCCCAGTGCAATCCAGAGGTGGAAGAGATCCTATATCCAGGTGAAGGTGGCCATTGAGTTTCTCAGGGCTGGGGCCACCTTGTC CATAGCCTCCGTCCACGCTGCCTGGAGCAGGTTGTTAGAGAGCTCTGGTTGTTGGGTCTTCCTCAGCTCCCTTCTGCCCCTCTCTACCTC TTCCACTCATGGAAGCCCCTCTACTGCTTATGAAGATTAAGGGTAGTATTTTCTAAGGAAGTGGAAAGAATTAAACTAGAAATCCACAAC CTCGGAAGAAGTGTTTCGAGTTTAACATGCGCTGTTTCTGCTTATGTGGTTCCTTCTCTAGAGCTGCTTTCCCATGGCTTTCAAAACATC AGGTTATTGTGGGGCTTCAGGTGTAAGGTCCTGGAAGTTCAGCAAAGTTTCGTGGACAAGACATGGGCACAGAGAGTAGAAGCAGAAATA AATGGTTCTATGTTTTCAACTTCCAGGGTTGGGGCAGGCCAGAGCAAGGCGGTCTCATCGAGGTGGGTGCTACCTGTGTGTGTGTAGATG AGTGTGCTGAAGGTGGGGAGGGCAGCACACAGCAGCTCATGGCAGAGCCGCCTCCTAGGTCTTGGCAAAGAGGCAAGCTGACGATAGACA TCTACCTATATTGTTAAGAAAGGGGTCGGGGGGATCAGCCAAGGTCCATCATTGCTTTTTTGCCGCGCCCCCCCCCCCCCGCCCCCATAG ATTGTCAGCTGTAAGTGAAACTCCTAGTGAAAAAGAGGGGAGCCCTGTGTTAGGAGTCCCCATAAACATGTACTGTAATTCTTTGTATAT >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000439151_chr5_176618885_+_16785nt GAGCCATGGGGCGCCATGTTGCCACCAGCTGCCACGTGGCCTGGCTTTTGGTGCTGATCTCTGGATGCTGGGGCCAGGTGAACCGGCTGC CCTTCTTCACCAACCACTTCTTTGATACATACCTGCTGATCAGCGAGGACACGCCTGTGGGTTCTTCTGTGACCCAGTTGCTGGCCCAAG ACATGGACAATGACCCCCTGGTGTTTGGCGTGTCTGGGGAGGAGGCCTCTCGCTTCTTTGCAGTGGAGCCTGACACTGGCGTGGTGTGGC TCCGGCAGCCACTGGACAGAGAGACCAAGTCAGAGTTCACCGTGGAGTTCTCTGTCAGCGACCACCAGGGGGTGATCACACGGAAGGTGA ACATCCAGGTTGGGGATGTGAATGACAACGCGCCCACATTTCACAATCAGCCCTACAGCGTCCGCATCCCTGAGGTAGGAGCCACTGGGA ATACACCAGTGGGGACGCCCATCTTCATCGTGAATGCCACAGACCCCGACTTGGGGGCAGGGGGCAGCGTCCTCTACTCCTTCCAGCCCC CCTCCCAATTCTTCGCCATTGACAGCGCCCGCGGTATCGTCACAGTGATCCGGGAGCTGGACTACGAGACCACACAGGCCTACCAGCTCA CGGTCAACGCCACAGATCAAGACAAGACCAGGCCTCTGTCCACCCTGGCCAACTTGGCCATCATCATCACAGATGTCCAGGACATGGACC CCATCTTCATCAACCTGCCTTACAGCACCAACATCTACGAGCATTCTCCTCCGGGCACGACGGTGCGCATCATCACCGCCATAGACCAGG ATAAAGGACGTCCCCGGGGCATTGGCTACACCATCGTTTCAGGGAATACCAACAGCATCTTTGCCCTGGACTACATCAGCGGAGTGCTGA CCTTGAATGGCCTGCTGGACCGGGAGAACCCCCTGTACAGCCATGGCTTCATCCTGACTGTGAAGGGCACGGAGCTGAACGATGACCGCA CCCCATCTGACGCTACAGTCACCACGACCTTCAATATCCTGGTTATTGACATCAATGACAATGCCCCGGAGTTCAACAGCTCCGAGTACA GCGTGGCCATCACTGAGCTGGCACAGGTCGGCTTTGCCCTTCCACTCTTCATCCAGGTGGTGGACAAGGATGAGAATTTGGGCCTGAACA GCATGTTTGAGGTGTACTTGGTGGGGAACAACTCCCACCACTTCATCATCTCCCCGACCTCCGTCCAGGGGAAGGCGGACATTCGTATTC GGGTGGCCATCCCACTGGACTACGAGACCGTGGACCGCTACGACTTTGATCTCTTTGCCAATGAGAGTGTGCCTGACCATGTGGGCTATG CCAAGGTGAAGATCACTCTCATCAATGAAAATGACAACCGGCCCATCTTCAGCCAGCCACTGTACAACATCAGCCTGTACGAGAACGTCA CCGTGGGGACCTCTGTGCTGACAGTCCTGGCAACTGACAATGATGCAGGCACCTTTGGGGAAGTCAGCTACTTCTTCAGTGATGACCCTG ACAGGTTCTCGCTGGACAAGGACACGGGACTCATCATGCTGATTGCCAGGCTGGACTATGAGCTCATCCAGCGCTTCACCCTGACGATCA TTGCCCGGGACGGGGGCGGCGAGGAGACCACAGGCCGGGTCAGGATCAATGTGTTGGATGTCAACGACAACGTGCCCACCTTCCAGAAGG ATGCCTACGTGGGTGCTCTGCGGGAGAACGAGCCTTCTGTCACACAGCTGGTGCGGCTCCGGGCAACAGATGAAGACTCCCCTCCCAACA ACCAGATCACCTACAGCATTGTCAGTGCATCTGCCTTTGGCAGCTACTTCGACATCAGCCTGTACGAGGGCTATGGAGTGATCAGCGTCA GTCGCCCCCTGGATTATGAACAGATATCCAATGGGCTGATTTATCTGACGGTCATGGCCATGGATGCTGGCAACCCCCCTCTCAACAGCA CCGTCCCTGTCACCATCGAGGTGTTTGATGAGAATGACAACCCTCCCACCTTCAGCAAGCCCGCCTACTTCGTCTCCGTGGTGGAGAACA TCATGGCAGGAGCCACGGTGCTGTTCCTGAATGCCACAGACCTGGACCGCTCCCGGGAGTACGGCCAGGAGTCCATCATCTACTCCTTGG AAGGCTCCACCCAGTTTCGGATCAATGCCCGCTCAGGGGAAATCACCACCACGTCTCTGCTTGACCGAGAGACCAAGTCTGAATACATCC TCATCGTTCGCGCAGTGGACGGGGGTGTGGGCCACAACCAGAAAACTGGCATCGCCACCGTAAACATCACCCTCCTGGACATCAATGACA ACCACCCCACGTGGAAGGACGCACCCTACTACATCAACCTGGTGGAGATGACCCCTCCAGACTCTGATGTGACCACGGTGGTGGCTGTTG ACCCAGACCTGGGGGAGAATGGCACCCTGGTGTACAGCATCCAGCCACCCAACAAGTTCTACAGCCTCAACAGCACCACGGGCAAGATCC GCACCACCCACGCCATGCTGGACCGGGAGAACCCCGACCCCCATGAGGCCGAGCTGATGCGCAAAATCGTCGTCTCTGTTACTGACTGTG GCAGGCCCCCTCTGAAAGCCACCAGCAGTGCCACAGTGTTTGTGAACCTCTTGGATCTCAATGACAATGACCCCACCTTTCAGAACCTGC CTTTTGTGGCCGAGGTGCTTGAAGGCATCCCGGCGGGGGTCTCCATCTACCAAGTGGTGGCCATCGACCTCGATGAGGGCCTGAACGGCC TGGTGTCCTACCGCATGCCGGTGGGCATGCCCCGCATGGACTTCCTCATCAACAGCAGCAGCGGCGTGGTGGTCACCACCACCGAGCTGG ACCGCGAGCGCATCGCGGAGTACCAGCTGCGGGTGGTGGCCAGTGATGCAGGCACGCCCACCAAGAGCTCCACCAGCACGCTCACCATCC ATGTGCTGGATGTGAACGACGAGACGCCCACCTTCTTCCCGGCCGTGTACAATGTGTCTGTGTCCGAGGACGTGCCACGCGAGTTCCGGG TGGTCTGGCTGAACTGCACGGACAACGACGTGGGCCTCAATGCAGAGCTCAGCTACTTCATCACAGGTGGCAACGTGGATGGGAAGTTCA GCGTGGGTTACCGCGATGCCGTTGTGAGAACCGTGGTGGGCCTGGACCGGGAGACCACAGCCGCCTACATGCTCATCCTGGAGGCCATCG ACAACGGCCCTGTAGGGAAGCGACACACGGGCACAGCCACCGTGTTCGTCACTGTCCTGGATGTGAATGACAACCGGCCCATCTTTCTGC AGAGCAGCTATGAGGCCAGCGTCCCTGAGGACATCCCTGAAGGCCACAGCATCTTGCAGCTGAAAGCCACGGACGCAGATGAGGGCGAGT TTGGGCGTGTGTGGTACCGCATCCTCCATGGTAACCATGGCAACAACTTCCGGATCCATGTCAGCAATGGGCTCCTGATGCGAGGGCCCC GGCCCCTGGACCGGGAGCGGAACTCATCCCACGTGCTGATAGTGGAGGCCTACAACCACGACCTGGGCCCCATGCGGAGCTCCGTCAGGG TGATTGTGTACGTGGAGGACATCAACGATGAGGCCCCCGTGTTCACACAGCAGCAGTACAGCCGTCTGGGGCTTCGAGAGACCGCAGGCA TTGGAACGTCAGTCATCGTGGTCCAAGCCACAGACCGAGACTCTGGGGATGGTGGCCTGGTGAACTACCGCATCCTGTCGGGCGCAGAGG GGAAGTTTGAGATTGACGAGAGCACAGGGCTTATCATCACCGTGAATTACCTGGACTACGAGACCAAGACCAGCTACATGATGAATGTGT CGGCCACTGACCAGGCCCCGCCCTTCAACCAGGGCTTCTGCAGCGTCTACATCACTCTGCTCAACGAGCTGGACGAGGCCGTGCAGTTCT CCAATGCCTCATACGAGGCTGCCATCCTGGAGAATCTGGCACTGGGTACTGAGATTGTGCGGGTCCAGGCCTACTCCATCGACAACCTCA ACCAAATCACGTACCGCTTCAACGCCTACACCAGCACCCAGGCCAAAGCCCTCTTCAAGATAGACGCCATCACGGGTGTGATCACAGTCC AGGGCCTGGTGGACCGTGAGAAGGGCGACTTCTATACCTTGACAGTGGTGGCAGATGACGGCGGCCCCAAGGTGGACTCCACCGTGAAGG TCTACATCACTGTGCTGGACGAGAATGACAACAGCCCCCGGTTTGACTTCACCTCCGACTCGGCGGTCAGCATACCCGAGGACTGCCCTG TGGGCCAGCGAGTGGCTACTGTCAAGGCCTGGGACCCTGATGCTGGCAGCAATGGGCAGGTGGTCTTCTCCCTGGCCTCTGGCAACATCG CGGGGGCCTTTGAGATCGTCACCACCAATGACTCCATTGGCGAAGTGTTTGTGGCCAGGCCCCTGGACAGAGAAGAGCTGGATCACTACA TCCTCCAGGTTGTGGCTTCTGACCGAGGCACCCCTCCACGGAAGAAGGACCACATCCTGCAGGTGACCATCCTGGACATCAATGACAACC CTCCAGTCATCGAGAGCCCCTTTGGATACAATGTCAGTGTGAATGAGAACGTGGGTGGAGGTACTGCTGTGGTCCAGGTGAGAGCCACTG ACCGTGACATCGGGATCAACAGTGTTCTGTCCTACTACATCACCGAGGGCAACAAGGACATGGCCTTCCGCATGGACCGCATCAGCGGTG AGATCGCCACACGGCCTGCCCCGCCTGACCGCGAGCGCCAGAGCTTCTACCACCTGGTGGCCACTGTGGAGGACGAGGGCACCCCAACCC TGTCGTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGC CCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGG CTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCC TTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTG CAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTG AAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAG ATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAAT TTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCT CTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTG CAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATA AACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTA TCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATG CTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAG CAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGG TTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGT CATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCC GAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTG ATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGG ATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTG ACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCA GTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGA GTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAA AGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCT TACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCAT CCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATC AGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAG AGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTG ATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAAC TCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTA AAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAA CTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTG ATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGC GGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAAC AAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACA AGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTC AGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTG AGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATT TAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAAT CTTGTGCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTG CAGCCAAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGG CCACAAGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAG GAGCTGCACTCAAGGAGAATGTCTGTCAGAATTGTGAAAAATTGGGTGAGCTGCTGTTATGTGAGGCTCAGTGCTGTGGGGCTTTCCACC TGGAGTGCCTTGGATTGACTGAGATGCCAAGAGGAAAATTTATCTGCAATGAATGTCGCACAGGAATCCATACCTGTTTTGTATGTAAGC AGAGTGGGGAAGATGTTAAAAGGTGCCTTCTACCCTTGTGTGGAAAGTTTTACCATGAAGAGTGTGTCCAGAAGTACCCACCCACTGTTA TGCAGAACAAGGGCTTCCGGTGCTCCCTCCACATCTGTATAACCTGTCATGCTGCTAATCCAGCCAATGTTTCTGCATCTAAAGGTCGGT TGATGCGCTGTGTCCGCTGTCCTGTGGCATACCACGCCAATGACTTTTGCCTGGCTGCTGGGTCAAAGATCCTTGCATCTAATAGTATCA TCTGCCCTAATCACTTTACCCCTAGGCGGGGCTGCCGAAATCATGAGCATGTTAATGTTAGCTGGTGCTTTGTGTGCTCAGAAGGAGGCA GCCTTCTGTGCTGTGATTCTTGCCCTGCTGCTTTTCATCGTGAATGCCTGAACATTGATATCCCTGAAGGAAACTGGTATTGCAATGACT GTAAAGCAGGCAAAAAGCCACACTACAGGGAGATTGTCTGGGTAAAAGTTGGACGATACAGGTGGTGGCCAGCTGAGATCTGCCATCCTC GAGCTGTTCCTTCCAACATTGATAAGATGAGACATGATGTGGGAGAGTTCCCAGTCCTCTTTTTTGGATCTAATGACTATTTGTGGACTC ACCAGGCCCGAGTCTTCCCTTACATGGAGGGTGACGTGAGCAGCAAGGATAAGATGGGCAAAGGAGTGGATGGGACATATAAAAAAGCTC TTCAGGAAGCTGCAGCAAGGTTTGAGGAATTAAAGGCCCAAAAAGAGCTAAGACAGCTGCAGGAAGACCGAAAGAATGACAAGAAGCCAC CACCTTATAAACATATAAAGGTAAACCGTCCTATTGGCAGGGTACAGATCTTCACTGCAGACTTATCTGAAATACCCCGTTGCAACTGTA AAGCTACTGATGAGAACCCCTGTGGGATAGACTCTGAATGCATCAACCGCATGCTGCTCTATGAGTGCCACCCCACAGTGTGTCCTGCCG GAGGGCGCTGTCAAAACCAGTGCTTTTCCAAGCGCCAATATCCAGAGGTTGAAATTTTCCGCACATTACAGCGGGGTTGGGGTCTACGGA CAAAAACAGATATTAAAAAGGGTGAATTTGTGAATGAGTATGTGGGTGAGCTTATAGATGAAGAAGAATGCAGAGCTCGAATTCGCTATG CTCAAGAACATGATATCACTAATTTCTATATGCTCACCCTAGACAAAGACCGAATCATTGATGCTGGTCCCAAAGGAAACTATGCTCGGT TCATGAATCATTGCTGCCAGCCCAACTGTGAAACACAGAAGTGGTCTGTGAATGGAGATACCCGTGTAGGCCTTTTTGCACTAAGTGACA TTAAAGCAGGCACTGAACTTACCTTCAACTACAACCTAGAATGTCTTGGGAATGGAAAGACTGTTTGCAAATGTGGAGCCCCGAACTGCA GTGGCTTCTTGGGTGTAAGGCCAAAGAATCAACCCATTGCCACGGAAGAAAAGTCAAAGAAATTCAAGAAGAAGCAACAGGGAAAGCGCA GGACCCAGGGTGAAATCACAAAGGAGCGAGAAGATGAGTGTTTTAGTTGTGGGGATGCTGGCCAGCTCGTCTCCTGCAAGAAACCAGGCT GCCCAAAAGTTTACCACGCAGACTGTCTCAATCTGACCAAGCGACCAGCAGGGAAATGGGAATGTCCGTGGCATCAGTGTGACATCTGCG GGAAGGAAGCAGCCTCCTTCTGTGAGATGTGCCCCAGCTCCTTTTGTAAGCAGCATCGAGAAGGGATGCTTTTCATTTCCAAACTGGATG GGCGTCTGTCTTGTACTGAGCATGACCCCTGTGGGCCCAATCCTCTGGAACCTGGGGAGATCCGTGAGTATGTGCCTCCCCCAGTACCGC TGCCTCCAGGGCCAAGCACTCACCTGGCAGAGCAATCAACAGGAATGGCTGCTCAGGCACCCAAAATGTCAGATAAACCTCCTGCTGACA CCAACCAGATGCTGTCGCTCTCCAAAAAAGCTCTGGCAGGGACTTGTCAGAGGCCATTGCTACCTGAAAGACCTCTTGAGAGAACTGACT CCAGGCCCCAGCCTTTAGATAAGGTCAGAGACCTCGCTGGGTCAGGGACCAAATCCCAATCCTTGGTTTCCAGCCAGAGGCCACTGGACA GGCCACCAGCAGTGGCAGGACCAAGACCCCAGCTAAGCGACAAACCCTCTCCAGTGACCAGCCCAAGCTCCTCACCCTCAGTCAGGTCCC AACCACTGGAAAGACCTCTGGGGACGGCTGACCCAAGGCTGGATAAATCCATAGGTGCTGCCAGCCCAAGGCCCCAGTCACTGGAGAAAA CCTCAGTTCCCACTGGCCTGAGACTTCCGCCGCCAGACAGACTGCTCATTACTAGCAGTCCCAAACCCCAGACTTCAGACAGGCCTACTG ACAAACCCCATGCCTCTTTGTCCCAGAGACTCCCACCTCCTGAGAAAGTACTATCAGCTGTGGTCCAGACCCTTGTAGCTAAAGAAAAAG CACTGAGGCCTGTGGACCAGAATACTCAGTCAAAAAATAGAGCTGCTTTGGTGATGGATCTCATAGACCTAACTCCTCGCCAGAAGGAGC GGGCAGCTTCACCTCATCAGGTCACACCACAGGCTGATGAGAAGATGCCAGTGTTGGAGTCAAGTTCATGGCCTGCCAGCAAAGGTCTGG GGCATATGCCGAGAGCTGTTGAGAAAGGCTGTGTGTCAGATCCTCTTCAGACATCTGGGAAAGCAGCAGCCCCTTCAGAGGACCCCTGGC AAGCTGTTAAATCACTCACCCAGGCCAGACTTCTTTCTCAGCCTCCTGCCAAGGCCTTTTTATATGAGCCAACAACTCAGGCCTCAGGAA GAGCTTCTGCAGGGGCTGAGCAGACCCCAGGGCCTCTTAGCCAATCCCCGGGCCTGGTGAAGCAGGCGAAGCAGATGGTCGGAGGCCAGC AACTACCTGCACTTGCCGCCAAGAGTGGGCAATCTTTTAGGTCTCTCGGGAAGGCCCCAGCCTCCCTCCCCACTGAAGAAAAGAAGTTGG TAACCACAGAGCAAAGTCCCTGGGCCCTGGGAAAAGCCTCATCACGGGCAGGGCTCTGGCCCATAGTGGCTGGACAGACACTGGCACAGT CTTGCTGGTCTGCTGGGAGCACACAGACATTGGCACAGACTTGCTGGTCTCTTGGAAGAGGGCAAGACCCCAAACCAGAGCAAAATACAC TTCCAGCTCTTAACCAGGCTCCTTCCAGTCACAAGTGTGCAGAATCAGAACAGAAGTAGTACCAATCAATGTCACATGAACAAACAAGCT GCCCCCAGGGTACCATTTGGGGAGGGGAAATCTTTTCTTTCTTTCCCCCTTAAAAAAAAACACATCTGCCCCGAACACTTTCCCACTGTT ATTCTTTCCTCATATCCCAACACTCAGAACTCTTGTGACATTAGCCAGTGGGGGCTTATGGTTGTGTGAACCATGTATGAAAATCCAGTG GGCCCCAACCAAGGAGACAGACAGACTTGGGTCTCTTTCCCCCAACTTTTCCACATGGTCATCGTGAAATAAAAAGTCCACTCTGGAGTC AAGTATGGAATTCAATTCCGCTGGTCAGGTTGGAAGGTATAGGGGCTCTCAAAGCGATTTCCCCAACCAGACAGAGCCCCATTGAGGGCA CCTAGGAACCCTTGGGAGGAAATGGTGTTCTTTCAAATCAGTGGCGATTTCCTGAGCATTCACGTGTTCTAGGCCGGGTGCTAGTCACTG ATGAGAGATACAGGCCTCATCCCTGTGAGCCTGGATTCCAAGGCTTTCAGGAACCTTTGACCAGGAAGTAACAGGAAGTTCTGAGGGGCC CTGGGGCTTTAGACTCATTTTGAAATGTCCTTTGTGGCACCAGAAGTGGTTGTGTTGAGGAAGTGTCTCTTGGCTGCGGTGTGCATGGGT GCGTGTGCATGCGCGCACACTCACAGAGGTCTCCTCTATAGATGCAAGGGTGCTGCATTGAGGCCAGCAAGGCTGTTGGCTGTGGGGTCG CCGCTGCTGCTTTTGTCTGGGCTGTGCAGAGTCTCAAGATCAGTCCTTGGAGGAGCAGGTGGTCAGGGGCAGTCGGGCTCTGTGCGAATG TAGATTTCCAGCAGTGGAAGAAGGCATTTGGCAAGCTTCTCTTTCTTTGCTTTTGTTTCTACCTATTTTTCTCTTTGTACATGAATCCAC CCCATCCCTATTTCCCTAAAACACTCAGGTGCTTTCAGATTTCAGAGCCTCGGGCAGTGGACATAGGGAATCTCTGGCAAGCTCTGAGCT AGACACACCAGCTTCAGGAAGAGTACCAGATCCTGATGGGAAATTTCTTTTCCCCATTCCTTTTCCCTCCTGAGTGGAGGGAGTCCTCTT CTTCGCCTCCCTGAGAATTGCTGTGCTCTGTATTGAGAGCACCTGCCTGCTGACTTAGCTCAAAGGCAAGCCAGAACCCTTCCCTGAAGA CTGGCAAGAGGTGGTGTTTAGAGCAACGTCCAGGCTAAGAGATGACTCCTATTAACTGCTGATTATCTGTTACTGCTGCCCTGAGCTGGG GCCCAAGGGCTGGGAAATCTGTTGGTGCTACCCTGCCCTACCATTCACCCAGCTCACAGACTGCCAACAGGAAGTGCTGTTTGGCTAGTT TCCTCCCACTTGTCTACCCCTCCTTTGTCCTTAGACCAACATGTTTACCTCTCTGCTTTGCCAACTTAGCCAGCAGGCCATCCCCGGCCC TAACGTCTCCTGGCCATTATCTCTTAGTTATGGCTTTCACGCTCTCAATAGGATTCTGTATTTGGTCCCAATTTCCTCAAGTTCTTATTG AGGTTACTCCCATCAATTCCACGGAGGGAACAGTAGTTATTATAGAAGCATTTGCGCTTTATCTAAAGATTAAAAATAGAATCTGCTTTT ATTTCCCAAAGTCTGTCTCTGAGGTTGAGACACTTGAACTCAGGCAGAGGGACGAGGCTGGGCAGGGCTGTCCTGAGTTTAGGGGCCTAT CCCTGCATTTCACTGAGACCTCGGAATCTCCTCTGTGAATTCCACCTGCCTAGTTCTCCCCTTTCATCCTCTCTCTCTTCCCACATCATC AAAGAGGAAAAGCTCTTTGTTCAAAAGGAAGAGAAAACGTAAAGCATCTTATTTTCTTTTAAAAGAATTTTAAACCATGAAAAAGATATT TTTAAAGAAATTCACCGAGAACATTAAAGTTCATTATATTAAGTATTTATCATGTGTGAGAATAATAAATATATAACTGCAGCTAGTAGG TCCCTTTCCCTAATCTTTTAGGTCATATGAGTAGGGTTTGCTTGGTGCCAGTCCTGTGCCCTTTTCTCTCCAGTCATCTGTAGTTGTGAT CAGAAAAAGGTATCTGCACTGCACTGTCAGAGTCTCCTTTCACTATGTTGTGTGTTAAATTACCGTAGCTCTTTGTTTCATGAAATAAAC TGTGAATTTGGGGGGGGCGGGGGGAGGGCGTGCAGGCCATGTAAAAATTTTCCGTGGAGAAGTTTGATTCTAAAGTAGCTTCTCTAAAGT AGGCTTTGGTAGGTAATCAACTTGACAGCAGTCTAGATGTCTCACAGGACAGGAGGGAGTGAGGGAAAGGGGCCATGATTGGCTGCTTTG TGGTTTTATTTTGGTTCTTTCCATTCTCCGCCATTCATTGGAGGCTTCGTTCCAGACCTGCCTGGGAAAACAGCTTCTGAGCCATTTTGG GGAGCAGTTCTTCATCTGAATGGATGGACATCTGGGCTTCCTTCAAGGGCCATTGAATGGGAACTAGAAAACCACTGGAAACTAGAAATT TGAGCTATTGGGCCCACCAGTAGCAGCATGTGATACTAGATGGTTAAAATCATGAAAGCAGTCACTATCCAATTAGAAGCAGAGTCACAA CAACTGTTGGGAAATGTGACTCTTGGAGGAAGGTGGGGAGGGAGTGGCCTTGCCAGCCCTGTGGGACGTCCCCTGAAGTTTGTAATAAGA CCCCTTTTCCAAAGGGATGTGAATTGGAGTGAAAAGGAAATCTTTCATCTTAGAAAACTTCTGGTCCTTAACGCAGGGTGGTATTTGGGT ATGTGCTTGGAAATTGAGATCTCAAGAGTGTTTGCCTTGGAGCCAGCTCCCCAGGAGGCCTTTTCCAGGGACAAGGCAAAAGTTGAAATT CTCCATGGGTAGCTAGAAAGCCAATACATCTAGCCCTGCTAAGTCAGAAAAAGATTATGAAAAATGTTGAAATTTACATTCAAAGCCTCA TTTGCTTATCTTGCTGGAGCCAACCCAGTCTAATAGCAAAATAGCTGTCATTGATACAGAAACATCCTCATTTTTAAATGTCTGCTTTAC CCTGTTACTGAGTTTGAGATGACTTAAATCACTGTGTTGACCCTCTTCTGAACCAAATCTTTAGCATTGATGAAAATAGTTATTTTATTC TTTACATCCTTCACCCCACACTATGGTCAGGGCATGAAACACCCTGTTGATCCCTTCCCAGGCTCGGCACTGTCTGCTCACTGGAGCCGG ACTCCCAGGTTGTAATTCTAATGTTGCCTCATGAGAACAGAATGGCAGAAAGTTTAGTCCTGACAGATTCCCCCATAGGGAGTAATGAGG ACAGCATGAAACTTGGATAGGTTTTACCCTTAGTCCCTATAAGGTGGATTTTACTAAGGTTTTTTAAATGATACTGTCATCCTCTTGGGG TTTATCAGCCAGGTTAGAGGAGCCCAGTGTCCTAACCTCTCTCAGATCATGGCAGAGAAGGAGCTGCCTCCAGCCCCTTTCTTGCTGAGT TTCATTTGAGCAGTTCCATGTGTAGACATTCCAAGTCACTGCTTGGTAGTTGCTGTGGGAGCCTGTCATTGGCTATGGCCAGTTAGTTCT CAGCTGAGCTTCCTAGGGCCAGTGCAACAGGGCCAGAGGCTGCTATAGTGTAAATTGAAATAAGAATAGATCATTGTTTTGTACACACAC ACAATAAAATGTAATGATGGTGCTAATTTCACGGTATAAATAAGCACTGCCAAGGGTTGAGGGACTGGCAGCTCAAGAAACCCGGGTTCC TGTTTGGGAGGAGATTTTATGTAGAAAAGTTTGAGGCTTTGTTAAAAGTGGGGAGAAGGAAGATCCTCAGTGAAGCCTGCACCCAACCCT GGAGTGGCCCAGTGCAATCCAGAGGTGGAAGAGATCCTATATCCAGGTGAAGGTGGCCATTGAGTTTCTCAGGGCTGGGGCCACCTTGTC CATAGCCTCCGTCCACGCTGCCTGGAGCAGGTTGTTAGAGAGCTCTGGTTGTTGGGTCTTCCTCAGCTCCCTTCTGCCCCTCTCTACCTC TTCCACTCATGGAAGCCCCTCTACTGCTTATGAAGATTAAGGGTAGTATTTTCTAAGGAAGTGGAAAGAATTAAACTAGAAATCCACAAC CTCGGAAGAAGTGTTTCGAGTTTAACATGCGCTGTTTCTGCTTATGTGGTTCCTTCTCTAGAGCTGCTTTCCCATGGCTTTCAAAACATC AGGTTATTGTGGGGCTTCAGGTGTAAGGTCCTGGAAGTTCAGCAAAGTTTCGTGGACAAGACATGGGCACAGAGAGTAGAAGCAGAAATA AATGGTTCTATGTTTTCAACTTCCAGGGTTGGGGCAGGCCAGAGCAAGGCGGTCTCATCGAGGTGGGTGCTACCTGTGTGTGTGTAGATG AGTGTGCTGAAGGTGGGGAGGGCAGCACACAGCAGCTCATGGCAGAGCCGCCTCCTAGGTCTTGGCAAAGAGGCAAGCTGACGATAGACA TCTACCTATATTGTTAAGAAAGGGGTCGGGGGGATCAGCCAAGGTCCATCATTGCTTTTTTGCCGCGCCCCCCCCCCCCCGCCCCCATAG ATTGTCAGCTGTAAGTGAAACTCCTAGTGAAAAAGAGGGGAGCCCTGTGTTAGGAGTCCCCATAAACATGTACTGTAATTCTTTGTATAT >In-frame_CDH23_ENST00000224721_chr10_73501678_+_NSD1_ENST00000347982_chr5_176618885_+_12332nt GAGCCATGGGGCGCCATGTTGCCACCAGCTGCCACGTGGCCTGGCTTTTGGTGCTGATCTCTGGATGCTGGGGCCAGGTGAACCGGCTGC CCTTCTTCACCAACCACTTCTTTGATACATACCTGCTGATCAGCGAGGACACGCCTGTGGGTTCTTCTGTGACCCAGTTGCTGGCCCAAG ACATGGACAATGACCCCCTGGTGTTTGGCGTGTCTGGGGAGGAGGCCTCTCGCTTCTTTGCAGTGGAGCCTGACACTGGCGTGGTGTGGC TCCGGCAGCCACTGGACAGAGAGACCAAGTCAGAGTTCACCGTGGAGTTCTCTGTCAGCGACCACCAGGGGGTGATCACACGGAAGGTGA ACATCCAGGTTGGGGATGTGAATGACAACGCGCCCACATTTCACAATCAGCCCTACAGCGTCCGCATCCCTGAGGTAGGAGCCACTGGGA ATACACCAGTGGGGACGCCCATCTTCATCGTGAATGCCACAGACCCCGACTTGGGGGCAGGGGGCAGCGTCCTCTACTCCTTCCAGCCCC CCTCCCAATTCTTCGCCATTGACAGCGCCCGCGGTATCGTCACAGTGATCCGGGAGCTGGACTACGAGACCACACAGGCCTACCAGCTCA CGGTCAACGCCACAGATCAAGACAAGACCAGGCCTCTGTCCACCCTGGCCAACTTGGCCATCATCATCACAGATGTCCAGGACATGGACC CCATCTTCATCAACCTGCCTTACAGCACCAACATCTACGAGCATTCTCCTCCGGGCACGACGGTGCGCATCATCACCGCCATAGACCAGG ATAAAGGACGTCCCCGGGGCATTGGCTACACCATCGTTTCAGGGAATACCAACAGCATCTTTGCCCTGGACTACATCAGCGGAGTGCTGA CCTTGAATGGCCTGCTGGACCGGGAGAACCCCCTGTACAGCCATGGCTTCATCCTGACTGTGAAGGGCACGGAGCTGAACGATGACCGCA CCCCATCTGACGCTACAGTCACCACGACCTTCAATATCCTGGTTATTGACATCAATGACAATGCCCCGGAGTTCAACAGCTCCGAGTACA GCGTGGCCATCACTGAGCTGGCACAGGTCGGCTTTGCCCTTCCACTCTTCATCCAGGTGGTGGACAAGGATGAGAATTTGGGCCTGAACA GCATGTTTGAGGTGTACTTGGTGGGGAACAACTCCCACCACTTCATCATCTCCCCGACCTCCGTCCAGGGGAAGGCGGACATTCGTATTC GGGTGGCCATCCCACTGGACTACGAGACCGTGGACCGCTACGACTTTGATCTCTTTGCCAATGAGAGTGTGCCTGACCATGTGGGCTATG CCAAGGTGAAGATCACTCTCATCAATGAAAATGACAACCGGCCCATCTTCAGCCAGCCACTGTACAACATCAGCCTGTACGAGAACGTCA CCGTGGGGACCTCTGTGCTGACAGTCCTGGCAACTGACAATGATGCAGGCACCTTTGGGGAAGTCAGCTACTTCTTCAGTGATGACCCTG ACAGGTTCTCGCTGGACAAGGACACGGGACTCATCATGCTGATTGCCAGGCTGGACTATGAGCTCATCCAGCGCTTCACCCTGACGATCA TTGCCCGGGACGGGGGCGGCGAGGAGACCACAGGCCGGGTCAGGATCAATGTGTTGGATGTCAACGACAACGTGCCCACCTTCCAGAAGG ATGCCTACGTGGGTGCTCTGCGGGAGAACGAGCCTTCTGTCACACAGCTGGTGCGGCTCCGGGCAACAGATGAAGACTCCCCTCCCAACA ACCAGATCACCTACAGCATTGTCAGTGCATCTGCCTTTGGCAGCTACTTCGACATCAGCCTGTACGAGGGCTATGGAGTGATCAGCGTCA GTCGCCCCCTGGATTATGAACAGATATCCAATGGGCTGATTTATCTGACGGTCATGGCCATGGATGCTGGCAACCCCCCTCTCAACAGCA CCGTCCCTGTCACCATCGAGGTGTTTGATGAGAATGACAACCCTCCCACCTTCAGCAAGCCCGCCTACTTCGTCTCCGTGGTGGAGAACA TCATGGCAGGAGCCACGGTGCTGTTCCTGAATGCCACAGACCTGGACCGCTCCCGGGAGTACGGCCAGGAGTCCATCATCTACTCCTTGG AAGGCTCCACCCAGTTTCGGATCAATGCCCGCTCAGGGGAAATCACCACCACGTCTCTGCTTGACCGAGAGACCAAGTCTGAATACATCC TCATCGTTCGCGCAGTGGACGGGGGTGTGGGCCACAACCAGAAAACTGGCATCGCCACCGTAAACATCACCCTCCTGGACATCAATGACA ACCACCCCACGTGGAAGGACGCACCCTACTACATCAACCTGGTGGAGATGACCCCTCCAGACTCTGATGTGACCACGGTGGTGGCTGTTG ACCCAGACCTGGGGGAGAATGGCACCCTGGTGTACAGCATCCAGCCACCCAACAAGTTCTACAGCCTCAACAGCACCACGGGCAAGATCC GCACCACCCACGCCATGCTGGACCGGGAGAACCCCGACCCCCATGAGGCCGAGCTGATGCGCAAAATCGTCGTCTCTGTTACTGACTGTG GCAGGCCCCCTCTGAAAGCCACCAGCAGTGCCACAGTGTTTGTGAACCTCTTGGATCTCAATGACAATGACCCCACCTTTCAGAACCTGC CTTTTGTGGCCGAGGTGCTTGAAGGCATCCCGGCGGGGGTCTCCATCTACCAAGTGGTGGCCATCGACCTCGATGAGGGCCTGAACGGCC TGGTGTCCTACCGCATGCCGGTGGGCATGCCCCGCATGGACTTCCTCATCAACAGCAGCAGCGGCGTGGTGGTCACCACCACCGAGCTGG ACCGCGAGCGCATCGCGGAGTACCAGCTGCGGGTGGTGGCCAGTGATGCAGGCACGCCCACCAAGAGCTCCACCAGCACGCTCACCATCC ATGTGCTGGATGTGAACGACGAGACGCCCACCTTCTTCCCGGCCGTGTACAATGTGTCTGTGTCCGAGGACGTGCCACGCGAGTTCCGGG TGGTCTGGCTGAACTGCACGGACAACGACGTGGGCCTCAATGCAGAGCTCAGCTACTTCATCACAGGTGGCAACGTGGATGGGAAGTTCA GCGTGGGTTACCGCGATGCCGTTGTGAGAACCGTGGTGGGCCTGGACCGGGAGACCACAGCCGCCTACATGCTCATCCTGGAGGCCATCG ACAACGGCCCTGTAGGGAAGCGACACACGGGCACAGCCACCGTGTTCGTCACTGTCCTGGATGTGAATGACAACCGGCCCATCTTTCTGC AGAGCAGCTATGAGGCCAGCGTCCCTGAGGACATCCCTGAAGGCCACAGCATCTTGCAGCTGAAAGCCACGGACGCAGATGAGGGCGAGT TTGGGCGTGTGTGGTACCGCATCCTCCATGGTAACCATGGCAACAACTTCCGGATCCATGTCAGCAATGGGCTCCTGATGCGAGGGCCCC GGCCCCTGGACCGGGAGCGGAACTCATCCCACGTGCTGATAGTGGAGGCCTACAACCACGACCTGGGCCCCATGCGGAGCTCCGTCAGGG TGATTGTGTACGTGGAGGACATCAACGATGAGGCCCCCGTGTTCACACAGCAGCAGTACAGCCGTCTGGGGCTTCGAGAGACCGCAGGCA TTGGAACGTCAGTCATCGTGGTCCAAGCCACAGACCGAGACTCTGGGGATGGTGGCCTGGTGAACTACCGCATCCTGTCGGGCGCAGAGG GGAAGTTTGAGATTGACGAGAGCACAGGGCTTATCATCACCGTGAATTACCTGGACTACGAGACCAAGACCAGCTACATGATGAATGTGT CGGCCACTGACCAGGCCCCGCCCTTCAACCAGGGCTTCTGCAGCGTCTACATCACTCTGCTCAACGAGCTGGACGAGGCCGTGCAGTTCT CCAATGCCTCATACGAGGCTGCCATCCTGGAGAATCTGGCACTGGGTACTGAGATTGTGCGGGTCCAGGCCTACTCCATCGACAACCTCA ACCAAATCACGTACCGCTTCAACGCCTACACCAGCACCCAGGCCAAAGCCCTCTTCAAGATAGACGCCATCACGGGTGTGATCACAGTCC AGGGCCTGGTGGACCGTGAGAAGGGCGACTTCTATACCTTGACAGTGGTGGCAGATGACGGCGGCCCCAAGGTGGACTCCACCGTGAAGG TCTACATCACTGTGCTGGACGAGAATGACAACAGCCCCCGGTTTGACTTCACCTCCGACTCGGCGGTCAGCATACCCGAGGACTGCCCTG TGGGCCAGCGAGTGGCTACTGTCAAGGCCTGGGACCCTGATGCTGGCAGCAATGGGCAGGTGGTCTTCTCCCTGGCCTCTGGCAACATCG CGGGGGCCTTTGAGATCGTCACCACCAATGACTCCATTGGCGAAGTGTTTGTGGCCAGGCCCCTGGACAGAGAAGAGCTGGATCACTACA TCCTCCAGGTTGTGGCTTCTGACCGAGGCACCCCTCCACGGAAGAAGGACCACATCCTGCAGGTGACCATCCTGGACATCAATGACAACC CTCCAGTCATCGAGAGCCCCTTTGGATACAATGTCAGTGTGAATGAGAACGTGGGTGGAGGTACTGCTGTGGTCCAGGTGAGAGCCACTG ACCGTGACATCGGGATCAACAGTGTTCTGTCCTACTACATCACCGAGGGCAACAAGGACATGGCCTTCCGCATGGACCGCATCAGCGGTG AGATCGCCACACGGCCTGCCCCGCCTGACCGCGAGCGCCAGAGCTTCTACCACCTGGTGGCCACTGTGGAGGACGAGGGCACCCCAACCC TGTCGTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGC CCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGG CTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCC TTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTG CAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTG AAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAG ATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAAT TTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCT CTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTG CAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATA AACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTA TCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATG CTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAG CAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGG TTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGT CATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCC GAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTG ATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGG ATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTG ACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCA GTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGA GTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAA AGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCT TACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCAT CCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATC AGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAG AGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTG ATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAAC TCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTA AAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAA CTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTG ATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGC GGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAAC AAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACA AGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTC AGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTG AGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATT TAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGTGCTATGAAGCTGGTCACCTGGAGAATGGCATAACTGAAT CTTGTGCCACATCTTATTCAAAAGATTTTGGTGGAGGCACTACCAAGATATTTGACAAGCCAAGGAAGCGAAAACGACAGAGGCATGCTG CAGCCAAGATGCAGTGTAAAAAAGTGAAAAATGATGACTCGTCAAAAGAGATTCCAGGCTCAGAGGGAGAACTAATGCCTCACAGGACGG CCACAAGCCCCAAGGAGACTGTTGAGGAAGGTGTAGAACACGATCCCGGGATGCCTGCCTCTAAAAAAATGCAGGGTGAACGCGGTGGAG GAGCTGCACTCAAGGAGAATGTCTGTCAGAATTGTGAAAAATTGGGTGAGCTGCTGTTATGTGAGGCTCAGTGCTGTGGGGCTTTCCACC TGGAGTGCCTTGGATTGACTGAGATGCCAAGAGGAAAATTTATCTGCAATGAATGTCGCACAGGAATCCATACCTGTTTTGTATGTAAGC AGAGTGGGGAAGATGTTAAAAGGTGCCTTCTACCCTTGTGTGGAAAGTTTTACCATGAAGAGTGTGTCCAGAAGTACCCACCCACTGTTA TGCAGAACAAGGGCTTCCGGTGCTCCCTCCACATCTGTATAACCTGTCATGCTGCTAATCCAGCCAATGTTTCTGCATCTAAAGGTCGGT TGATGCGCTGTGTCCGCTGTCCTGTGGCATACCACGCCAATGACTTTTGCCTGGCTGCTGGGTCAAAGATCCTTGCATCTAATAGTATCA TCTGCCCTAATCACTTTACCCCTAGGCGGGGCTGCCGAAATCATGAGCATGTTAATGTTAGCTGGTGCTTTGTGTGCTCAGAAGGAGGCA GCCTTCTGTGCTGTGATTCTTGCCCTGCTGCTTTTCATCGTGAATGCCTGAACATTGATATCCCTGAAGGAAACTGGTATTGCAATGACT GTAAAGCAGGCAAAAAGCCACACTACAGGGAGATTGTCTGGGTAAAAGTTGGACGATACAGGTGGTGGCCAGCTGAGATCTGCCATCCTC GAGCTGTTCCTTCCAACATTGATAAGATGAGACATGATGTGGGAGAGTTCCCAGTCCTCTTTTTTGGATCTAATGACTATTTGTGGACTC ACCAGGCCCGAGTCTTCCCTTACATGGAGGGTGACGTGAGCAGCAAGGATAAGATGGGCAAAGGAGTGGATGGGACATATAAAAAAGCTC TTCAGGAAGCTGCAGCAAGGTTTGAGGAATTAAAGGCCCAAAAAGAGCTAAGACAGCTGCAGGAAGACCGAAAGAATGACAAGAAGCCAC CACCTTATAAACATATAAAGGTAAACCGTCCTATTGGCAGGGTACAGATCTTCACTGCAGACTTATCTGAAATACCCCGTTGCAACTGTA AAGCTACTGATGAGAACCCCTGTGGGATAGACTCTGAATGCATCAACCGCATGCTGCTCTATGAGTGCCACCCCACAGTGTGTCCTGCCG GAGGGCGCTGTCAAAACCAGTGCTTTTCCAAGCGCCAATATCCAGAGGTTGAAATTTTCCGCACATTACAGCGGGGTTGGGGTCTACGGA CAAAAACAGATATTAAAAAGGGTGAATTTGTGAATGAGTATGTGGGTGAGCTTATAGATGAAGAAGAATGCAGAGCTCGAATTCGCTATG CTCAAGAACATGATATCACTAATTTCTATATGCTCACCCTAGACAAAGACCGAATCATTGATGCTGGTCCCAAAGGAAACTATGCTCGGT TCATGAATCATTGCTGCCAGCCCAACTGTGAAACACAGAAGTGGTCTGTGAATGGAGATACCCGTGTAGGCCTTTTTGCACTAAGTGACA TTAAAGCAGGCACTGAACTTACCTTCAACTACAACCTAGAATGTCTTGGGAATGGAAAGACTGTTTGCAAATGTGGAGCCCCGAACTGCA GTGGCTTCTTGGGTGTAAGGCCAAAGAATCAACCCATTGCCACGGAAGAAAAGTCAAAGAAATTCAAGAAGAAGCAACAGGGAAAGCGCA GGACCCAGGGTGAAATCACAAAGGAGCGAGAAGATGAGTGTTTTAGTTGTGGGGATGCTGGCCAGCTCGTCTCCTGCAAGAAACCAGGCT GCCCAAAAGTTTACCACGCAGACTGTCTCAATCTGACCAAGCGACCAGCAGGGAAATGGGAATGTCCGTGGCATCAGTGTGACATCTGCG GGAAGGAAGCAGCCTCCTTCTGTGAGATGTGCCCCAGCTCCTTTTGTAAGCAGCATCGAGAAGGGATGCTTTTCATTTCCAAACTGGATG GGCGTCTGTCTTGTACTGAGCATGACCCCTGTGGGCCCAATCCTCTGGAACCTGGGGAGATCCGTGAGTATGTGCCTCCCCCAGTACCGC TGCCTCCAGGGCCAAGCACTCACCTGGCAGAGCAATCAACAGGAATGGCTGCTCAGGCACCCAAAATGTCAGATAAACCTCCTGCTGACA CCAACCAGATGCTGTCGCTCTCCAAAAAAGCTCTGGCAGGGACTTGTCAGAGGCCATTGCTACCTGAAAGACCTCTTGAGAGAACTGACT CCAGGCCCCAGCCTTTAGATAAGGTCAGAGACCTCGCTGGGTCAGGGACCAAATCCCAATCCTTGGTTTCCAGCCAGAGGCCACTGGACA GGCCACCAGCAGTGGCAGGACCAAGACCCCAGCTAAGCGACAAACCCTCTCCAGTGACCAGCCCAAGCTCCTCACCCTCAGTCAGGTCCC AACCACTGGAAAGACCTCTGGGGACGGCTGACCCAAGGCTGGATAAATCCATAGGTGCTGCCAGCCCAAGGCCCCAGTCACTGGAGAAAA CCTCAGTTCCCACTGGCCTGAGACTTCCGCCGCCAGACAGACTGCTCATTACTAGCAGTCCCAAACCCCAGACTTCAGACAGGCCTACTG ACAAACCCCATGCCTCTTTGTCCCAGAGACTCCCACCTCCTGAGAAAGTACTATCAGCTGTGGTCCAGACCCTTGTAGCTAAAGAAAAAG CACTGAGGCCTGTGGACCAGAATACTCAGTCAAAAAATAGAGCTGCTTTGGTGATGGATCTCATAGACCTAACTCCTCGCCAGAAGGAGC GGGCAGCTTCACCTCATCAGGTCACACCACAGGCTGATGAGAAGATGCCAGTGTTGGAGTCAAGTTCATGGCCTGCCAGCAAAGGTCTGG GGCATATGCCGAGAGCTGTTGAGAAAGGCTGTGTGTCAGATCCTCTTCAGACATCTGGGAAAGCAGCAGCCCCTTCAGAGGACCCCTGGC AAGCTGTTAAATCACTCACCCAGGCCAGACTTCTTTCTCAGCCTCCTGCCAAGGCCTTTTTATATGAGCCAACAACTCAGGCCTCAGGAA GAGCTTCTGCAGGGGCTGAGCAGACCCCAGGGCCTCTTAGCCAATCCCCGGGCCTGGTGAAGCAGGCGAAGCAGATGGTCGGAGGCCAGC AACTACCTGCACTTGCCGCCAAGAGTGGGCAATCTTTTAGGTCTCTCGGGAAGGCCCCAGCCTCCCTCCCCACTGAAGAAAAGAAGTTGG TAACCACAGAGCAAAGTCCCTGGGCCCTGGGAAAAGCCTCATCACGGGCAGGGCTCTGGCCCATAGTGGCTGGACAGACACTGGCACAGT CTTGCTGGTCTGCTGGGAGCACACAGACATTGGCACAGACTTGCTGGTCTCTTGGAAGAGGGCAAGACCCCAAACCAGAGCAAAATACAC TTCCAGCTCTTAACCAGGCTCCTTCCAGTCACAAGTGTGCAGAATCAGAACAGAAGTAGTACCAATCAATGTCACATGAACAAACAAGCT GCCCCCAGGGTACCATTTGGGGAGGGGAAATCTTTTCTTTCTTTCCCCCTTAAAAAAAAACACATCTGCCCCGAACACTTTCCCACTGTT ATTCTTTCCTCATATCCCAACACTCAGAACTCTTGTGACATTAGCCAGTGGGGGCTTATGGTTGTGTGAACCATGTATGAAAATCCAGTG GGCCCCAACCAAGGAGACAGACAGACTTGGGTCTCTTTCCCCCAACTTTTCCACATGGTCATCGTGAAATAAAAAGTCCACTCTGGAGTC |
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FusionGenePPI for CDH23_NSD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CDH23 | USH1C, LYN, CLK1, PPME1, GOPC, NCKAP1, ABI1, NXN, WASF1, CYFIP1, SLC9A3R2 | NSD1 | ZNF496, AR, RELA, AFF1, SIRT7, HIST4H4, TNFRSF21, RARA, RXRA, ESR1, PPARG, VDR, THRB, RORA, RORB, HNF4G, NR2F6, ESRRA, NR5A2, NR6A1, NR2F1, NR2F2, NR2E1, HIST3H3, HIST1H1B, ATRX, SNORD3A, HIST1H1D, HIST1H1C, GAR1, HIST1H3A, HIST1H4A, POLR2A, ZFY, ZBTB48, ZNF692, MECP2, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CDH23_NSD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CDH23_NSD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CDH23 | C1832394 | Deafness, Autosomal Recessive 12 | 8 | CTD_human;UNIPROT |
| Hgene | CDH23 | C1832845 | USHER SYNDROME, TYPE ID | 6 | UNIPROT |
| Hgene | CDH23 | C0032273 | Pneumoconiosis | 1 | CTD_human |
| Tgene | NSD1 | C0175695 | Sotos' syndrome | 14 | CTD_human;ORPHANET;UNIPROT |
| Tgene | NSD1 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Tgene | NSD1 | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Tgene | NSD1 | C0265210 | Weaver syndrome | 1 | CTD_human;ORPHANET |
| Tgene | NSD1 | C3714756 | Intellectual Disability | 1 | CTD_human |
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