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Fusion gene ID: 6212 |
FusionGeneSummary for CD59_FBXO3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CD59_FBXO3 | Fusion gene ID: 6212 | Hgene | Tgene | Gene symbol | CD59 | FBXO3 | Gene ID | 966 | 26273 |
| Gene name | CD59 molecule (CD59 blood group) | F-box protein 3 | |
| Synonyms | 16.3A5|1F5|EJ16|EJ30|EL32|G344|HRF-20|HRF20|MAC-IP|MACIF|MEM43|MIC11|MIN1|MIN2|MIN3|MIRL|MSK21|p18-20 | FBA|FBX3 | |
| Cytomap | 11p13 | 11p13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CD59 glycoprotein1F5 antigen20 kDa homologous restriction factorCD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)CD59 molecule, complement regulatory proteinLy-6-like proteinMEM43 antigenT cell-acti | F-box only protein 3F-box protein FBX3 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P13987 | Q9UK99 | |
| Ensembl transtripts involved in fusion gene | ENST00000534312, ENST00000395850, ENST00000533403, ENST00000351554, ENST00000415002, ENST00000445143, ENST00000426650, ENST00000437761, ENST00000527577, ENST00000528700, | ENST00000526785, ENST00000265651, ENST00000530401, ENST00000531080, ENST00000532057, ENST00000534136, ENST00000448981, ENST00000533103, | |
| Fusion gene scores | * DoF score | 5 X 8 X 2=80 | 4 X 3 X 1=12 |
| # samples | 14 | 4 | |
| ** MAII score | log2(14/80*10)=0.807354922057604 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/12*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CD59 [Title/Abstract] AND FBXO3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A7-A13D-01B | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000534312 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| In-frame | ENST00000534312 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| In-frame | ENST00000534312 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| 5CDS-intron | ENST00000534312 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| 5CDS-intron | ENST00000534312 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| 5CDS-intron | ENST00000534312 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| 5CDS-intron | ENST00000534312 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| 5CDS-5UTR | ENST00000534312 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000395850 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000395850 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000395850 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000395850 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000395850 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000395850 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000395850 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000395850 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000533403 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000533403 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000533403 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000533403 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000533403 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000533403 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000533403 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000533403 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000351554 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000351554 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000351554 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000351554 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000351554 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000351554 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000351554 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000351554 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000415002 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000415002 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000415002 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000415002 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000415002 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000415002 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000415002 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000415002 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000445143 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000445143 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000445143 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000445143 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000445143 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000445143 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000445143 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000445143 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000426650 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000426650 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000426650 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000426650 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000426650 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000426650 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000426650 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000426650 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000437761 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000437761 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000437761 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000437761 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000437761 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000437761 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000437761 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000437761 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000527577 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000527577 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000527577 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000527577 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000527577 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000527577 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000527577 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000527577 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000528700 | ENST00000526785 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000528700 | ENST00000265651 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-3CDS | ENST00000528700 | ENST00000530401 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000528700 | ENST00000531080 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000528700 | ENST00000532057 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000528700 | ENST00000534136 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-intron | ENST00000528700 | ENST00000448981 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
| intron-5UTR | ENST00000528700 | ENST00000533103 | CD59 | chr11 | 33731752 | - | FBXO3 | chr11 | 33780147 | - |
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FusionProtFeatures for CD59_FBXO3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CD59 | FBXO3 |
| Potent inhibitor of the complement membrane attackcomplex (MAC) action. Acts by binding to the C8 and/or C9complements of the assembling MAC, thereby preventingincorporation of the multiple copies of C9 required for completeformation of the osmolytic pore. This inhibitor appears to bespecies-specific. Involved in signal transduction for T-cellactivation complexed to a protein tyrosine kinase. The soluble form from urine retains its specificcomplement binding activity, but exhibits greatly reduced abilityto inhibit MAC assembly on cell membranes. | Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates theubiquitination of HIPK2 and probably that of EP300, leading torapid degradation by the proteasome. In the presence of PML, HIPK2ubiquitination still occurs, but degradation is prevented. PML,HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. {ECO:0000269|PubMed:18809579}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000265651 | - | 2 | 11 | 418_452 | 119 | 472 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000265651 | - | 2 | 11 | 453_456 | 119 | 472 | Compositional bias | Note=Poly-Arg |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000265651 | - | 2 | 11 | 463_466 | 119 | 472 | Compositional bias | Note=Poly-Arg |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000448981 | - | 2 | 10 | 418_452 | 119 | 416 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000448981 | - | 2 | 10 | 453_456 | 119 | 416 | Compositional bias | Note=Poly-Arg |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000448981 | - | 2 | 10 | 463_466 | 119 | 416 | Compositional bias | Note=Poly-Arg |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000530401 | - | 2 | 10 | 418_452 | 114 | 411 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000530401 | - | 2 | 10 | 453_456 | 114 | 411 | Compositional bias | Note=Poly-Arg |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000530401 | - | 2 | 10 | 463_466 | 114 | 411 | Compositional bias | Note=Poly-Arg |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000265651 | - | 2 | 11 | 278_408 | 119 | 472 | Domain | ApaG |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000448981 | - | 2 | 10 | 278_408 | 119 | 416 | Domain | ApaG |
| Tgene | >FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000530401 | - | 2 | 10 | 278_408 | 114 | 411 | Domain | ApaG |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000351554 | - | 1 | 5 | 26_108 | -43 | 129 | Domain | Note=UPAR/Ly6 |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000395850 | - | 1 | 4 | 26_108 | -26 | 129 | Domain | Note=UPAR/Ly6 |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000415002 | - | 1 | 3 | 26_108 | -89 | 129 | Domain | Note=UPAR/Ly6 |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000426650 | - | 1 | 4 | 26_108 | -18 | 129 | Domain | Note=UPAR/Ly6 |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000437761 | - | 1 | 4 | 26_108 | -58 | 129 | Domain | Note=UPAR/Ly6 |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000445143 | - | 1 | 4 | 26_108 | -37 | 129 | Domain | Note=UPAR/Ly6 |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000527577 | - | 1 | 5 | 26_108 | -60 | 129 | Domain | Note=UPAR/Ly6 |
| Hgene | >CD59 | chr11:33731752 | chr11:33780147 | ENST00000528700 | - | 1 | 6 | 26_108 | -74 | 129 | Domain | Note=UPAR/Ly6 |
| Tgene | FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000265651 | - | 2 | 11 | 10_56 | 119 | 472 | Domain | F-box |
| Tgene | FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000448981 | - | 2 | 10 | 10_56 | 119 | 416 | Domain | F-box |
| Tgene | FBXO3 | chr11:33731752 | chr11:33780147 | ENST00000530401 | - | 2 | 10 | 10_56 | 114 | 411 | Domain | F-box |
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FusionGeneSequence for CD59_FBXO3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| * Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for CD59_FBXO3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CD59 | NCR1, NCR3, C9, C8A, CD8A, SMAD4, CFTR, PAN2, GRB2, EGFR, ABCE1, CD27, TINAGL1, DBN1, FLNA, UBE2A, ATP6AP2, SYNPO, MAPRE1, GOLT1B, TMPRSS11B, GALK2, IGFBP1 | FBXO3 | RBX1, TNFAIP3, CUL3, CUL1, COPS5, NEDD8, PML, SKP1, HIPK2, EP300, HSP90AA1, DCP2, IDS, SMURF1, MCM2, CDC73, AIRE, PTPDC1, FBXO3, INO80B, ZNHIT2, FBXL2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CD59_FBXO3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CD59_FBXO3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CD59 | C2676767 | CD59 Deficiency | 1 | CTD_human;ORPHANET;UNIPROT |
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