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Fusion gene ID: 5230 |
FusionGeneSummary for CACNB1_LASP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CACNB1_LASP1 | Fusion gene ID: 5230 | Hgene | Tgene | Gene symbol | CACNB1 | LASP1 | Gene ID | 782 | 3927 |
| Gene name | calcium voltage-gated channel auxiliary subunit beta 1 | LIM and SH3 protein 1 | |
| Synonyms | CAB1|CACNLB1|CCHLB1 | Lasp-1|MLN50 | |
| Cytomap | 17q12 | 17q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | voltage-dependent L-type calcium channel subunit beta-1calcium channel voltage-dependent subunit beta 1calcium channel, L type, beta 1 polypeptidecalcium channel, voltage-dependent, beta 1 subunitdihydropyridine-sensitive L-type, calcium channel beta- | LIM and SH3 domain protein 1metastatic lymph node gene 50 protein | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q02641 | Q14847 | |
| Ensembl transtripts involved in fusion gene | ENST00000394303, ENST00000394310, ENST00000344140, ENST00000582877, | ENST00000318008, ENST00000433206, ENST00000435347, | |
| Fusion gene scores | * DoF score | 13 X 8 X 3=312 | 13 X 12 X 7=1092 |
| # samples | 12 | 16 | |
| ** MAII score | log2(12/312*10)=-1.37851162325373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/1092*10)=-2.77082904603249 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CACNB1 [Title/Abstract] AND LASP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-BH-A0B7-01A | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000394303 | ENST00000318008 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000394303 | ENST00000433206 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000394303 | ENST00000435347 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000394310 | ENST00000318008 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000394310 | ENST00000433206 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000394310 | ENST00000435347 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000344140 | ENST00000318008 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000344140 | ENST00000433206 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| In-frame | ENST00000344140 | ENST00000435347 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| 5UTR-3CDS | ENST00000582877 | ENST00000318008 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| 5UTR-3CDS | ENST00000582877 | ENST00000433206 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
| 5UTR-3CDS | ENST00000582877 | ENST00000435347 | CACNB1 | chr17 | 37351137 | - | LASP1 | chr17 | 37054665 | + |
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FusionProtFeatures for CACNB1_LASP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CACNB1 | LASP1 |
| The beta subunit of voltage-dependent calcium channelscontributes to the function of the calcium channel by increasingpeak calcium current, shifting the voltage dependencies ofactivation and inactivation, modulating G protein inhibition andcontrolling the alpha-1 subunit membrane targeting. | Plays an important role in the regulation of dynamicactin-based, cytoskeletal activities. Agonist-dependent changes inLASP1 phosphorylation may also serve to regulate actin-associatedion transport activities, not only in the parietal cell but alsoin certain other F-actin-rich secretory epithelial cell types (Bysimilarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >LASP1 | chr17:37351137 | chr17:37054665 | ENST00000318008 | + | 2 | 7 | 201_204 | 83 | 262 | Compositional bias | Note=Poly-Gly |
| Tgene | >LASP1 | chr17:37351137 | chr17:37054665 | ENST00000435347 | + | 2 | 8 | 201_204 | 83 | 708 | Compositional bias | Note=Poly-Gly |
| Tgene | >LASP1 | chr17:37351137 | chr17:37054665 | ENST00000318008 | + | 2 | 7 | 202_261 | 83 | 262 | Domain | SH3 |
| Tgene | >LASP1 | chr17:37351137 | chr17:37054665 | ENST00000435347 | + | 2 | 8 | 202_261 | 83 | 708 | Domain | SH3 |
| Tgene | >LASP1 | chr17:37351137 | chr17:37054665 | ENST00000318008 | + | 2 | 7 | 97_131 | 83 | 262 | Repeat | Note=Nebulin 2 |
| Tgene | >LASP1 | chr17:37351137 | chr17:37054665 | ENST00000435347 | + | 2 | 8 | 97_131 | 83 | 708 | Repeat | Note=Nebulin 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CACNB1 | chr17:37351137 | chr17:37054665 | ENST00000344140 | - | 2 | 13 | 100_169 | 57 | 524 | Domain | SH3 |
| Hgene | >CACNB1 | chr17:37351137 | chr17:37054665 | ENST00000394303 | - | 2 | 14 | 100_169 | 57 | 599 | Domain | SH3 |
| Hgene | >CACNB1 | chr17:37351137 | chr17:37054665 | ENST00000394310 | - | 2 | 13 | 100_169 | 57 | 479 | Domain | SH3 |
| Tgene | LASP1 | chr17:37351137 | chr17:37054665 | ENST00000318008 | + | 2 | 7 | 5_56 | 83 | 262 | Domain | LIM zinc-binding |
| Tgene | LASP1 | chr17:37351137 | chr17:37054665 | ENST00000435347 | + | 2 | 8 | 5_56 | 83 | 708 | Domain | LIM zinc-binding |
| Tgene | LASP1 | chr17:37351137 | chr17:37054665 | ENST00000318008 | + | 2 | 7 | 61_95 | 83 | 262 | Repeat | Note=Nebulin 1 |
| Tgene | LASP1 | chr17:37351137 | chr17:37054665 | ENST00000435347 | + | 2 | 8 | 61_95 | 83 | 708 | Repeat | Note=Nebulin 1 |
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FusionGeneSequence for CACNB1_LASP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_236aa MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ ISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_708nt ATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAA TACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGTGCGCTAC AAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTCCAGAGAATCAAGAAGACCCAGGACCAG ATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAGGGCATGGAGCCAGAGCGTCGGGATTCA CAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGTGCCCCGGTTTACCAGCAGCCCCAGCAG CAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGCAGCGCCCCAGGTGGTGGCGGGAAGCGG TACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGACACCATCGTCAACGTGCAGCAGATCGAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_3908nt GAGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAG CTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGG CCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGA GGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATC CAACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCT CCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGA GGGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAG TGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCG CAGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGA CACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTA CGTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCT TCAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCAC TTCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGG AGGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCAC ATACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCT TGGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCC CACCTGGGGTCTCTCTCCCTACCTCCCTCCTCAGGGGCAACAACAGGAGAATGGGGTTCCTGCTGTGGGGCGAATTCATCCCCTCCCCGC GCGTTCCTTCGCACACTGTGATTTTGCCCTCCTGCCCACGCAGACCTGCAGCGGGCAAAGAGCTCCCGAGGAAGCACAGCTTGGGTCAGG TTCTTGCCTTTCTTAATTTTAGGGACAGCTACCGGAAGGAGGGGAACAAGGAGTTCTCTTCCGCAGCCCCTTTCCCCACGCCCACCCCCA GTCTCCAGGGACCCTTGCCTGCCTCCTAGGCTGGAAGCCATGGTCCCGAAGTGTAGGGCAAGGGTGCCTCAGGACCTTTTGGTCTTCAGC CTCCCTCAGCCCCCAGGATCTGGGTTAGGTGGCCGCTCCTCCCTGCTCCTCATGGGAAGATGTCTCAGAGCCTTCCATGACCTCCCCTCC CCAGCCCAATGCCAAGTGGACTTGGAGCTGCACAAAGTCAGCAGGGACCACTAAATCTCCAAGACCTGGTGTGCGGAGGCAGGAGCATGT ATGTCTGCAGGTGTCTGACACGCAAGTGTGTGAGTGTGAGTGTGAGAGATGGGGCGGGGGTGTGTCTGTAGGTGTCTCTGGGCCTGTGTG TGGGTGGGGTTATGTGAGGGTATGAAGAGCTGTCTTCCCCTGAGAGTTTCCTCAGAACCCACAGTGAGAGGGGAGGGCTCCTGGGGCAGA GAAGTTCCTTAGGTTTTCTTTGGAATGAAATTCCTCCTTCCCCCCATCTCTGAGTGGAGGAAGCCCACCAATCTGCCCTTTGCAGTGTGC AGGGTGGAAGGTAAGAGGTTGGTGTGGAGTTGGGGCTGCCATAGGGTCTGCAGCCTGCTGGGGCTAAGCGGTGGAGGAAGGCTCTGTCAC TCCAGGCATATGTTTCCCCATCTCTGTCTGGGGCTACAGAATAGGGTGGCAGAAGTGTCACCCTGTGGGTGTCTCCCTCGGGGGCTCTTC CCCTAGACCTCCCCCTCACTTACATAAAGCTCCCTTGAAGCAAGAAAGAGGGTCCCAGGGCTGCAAAACTGGAAGCACAGCCTCGGGGAT GGGGAGGGAAAGACGGTGCTATATCCAGTTCCTGCTCTCTGCTCATGGGTGGCTGTGACAACCCTGGCCTCACTTGATTCATCTCTGGTT TTCTTGCCACCCTCTGGGAGTCCCCATCCCATTTTCATCCTGAGCCCAACCAGGCCCTGCCATTGGCCTCTTGTCCCTTGGCACACTTGT ACCCACAGGTGAGGGGCAGGACCTGAAGGTATTGGCCTGTTCAACAATCAGTCATCATGGGTGTTTTTGTCAACTGCTTGTTAATTGATT TGGGGATGTTTGCCCCGAATGAGAGGTTGAGGAAAAGACTGTGGGTGGGGAGGCCCTGCCTGACCCATCCCTTTTCCTTTCTGGCCCCAG CCTAGGTGGAGGCAAGTGGAATATCTTATATTGGGCGATTTGGGGGCTCGGGGAGGCAGAGAATCTCTTGGGAGTCTTGGGTGGCGCTGG TGCATTCTGTTTCCTCTTGATCTCAAAGCACAATGTGGATTTGGGGACCAAAGGTCAGGGACACATCCCCTTAGAGGACCTGAGTTTGGG AGAGTGGTGAGTGGAAGGGAGGAGCAGCAAGAAGCAGCCTGTTTTCACTCAGCTTAATTCTCCTTCCCAGATAAGGCAAGCCAGTCATGG AATCTTGCTGCAGGCCCTCCCTCTACTCTTCCTGTCCTAAAAATAGGGGCCGTTTTCTTACACACCCCCAGAGAGAGGAGGGACTGTCAC ACTGGTGCTGAGTGACCGGGGGCTGCTGGGCGTCTGTTCTTTACCAAAACCATCCATCCCTAGAAGAGCACAGAGCCCTGAGGGGCTGGG CTGGGCTGGGCTGAGCCCCTGGTCTTCTCTACAGTTCACAGAGGTCTTTCAGCTCATTTAATCCCAGGAAAGAGGCATCAAAGCTAGAAT GTGAATATAACTTTTGTGGACCAATACTAAGAATAACAAGAAGCCCAGTGGTGAGGAAAGTGCGTTCTCCCAGCACTGCCTCCTGTTTTC TCCCTCTCATGTCCCTCCAGGGAAAATGACTTTATTGCTTAATTTCTGCCTTTCCCCCCTCACACATGCACTTTTGGGCCTTTTTTTATA GCTGGAAAAAACAAAATACCACCCTACAAACCTGTATTTAAAAAGAAACAGAAATGACCACGTGAAATTTGCCTCTGTCCAAACATTTCA TCCGTGTGTATGTGTATGTGTGTGAGTGTGTGAAGCCGCCAGTTCATCTTTTTATATGGGGTTGTTGTCTCATTTTGGTCTGTTTTGGTC CCCTCCCTCGTGGGCTTGTGCTCGGGATCAAACCTTTCTGGCCTGTTATGATTCTGAACATTTGACTTGAACCACAAGTGAATCTTTCTC >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_1464nt GAGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAG CTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGG CCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGA GGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATC CAACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCT CCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGA GGGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAG TGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCG CAGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGA CACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTA CGTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCT TCAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCAC TTCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGG AGGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCAC ATACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCT TGGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCC >In-frame_CACNB1_ENST00000394303_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_3575nt GAGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAG CTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGG CCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGA GGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATC CAACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCT CCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGA GGGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAG TGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCG CAGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGA CACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTA CGTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCT TCAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCAC TTCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGG AGGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCAC ATACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCT TGGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCC CACCTGGGGTCTCTCTCCCTACCTCCCTCCTCAGGGGCAACAACAGGAGAATGGGGTTCCTGCTGTGGGGCGAATTCATCCCCTCCCCGC GCGTTCCTTCGCACACTGTGATTTTGCCCTCCTGCCCACGCAGACCTGCAGCGGGCAAAGAGCTCCCGAGGAAGCACAGCTTGGGTCAGG TTCTTGCCTTTCTTAATTTTAGGGACAGCTACCGGAAGGAGGGGAACAAGGAGTTCTCTTCCGCAGCCCCTTTCCCCACGCCCACCCCCA GTCTCCAGGGACCCTTGCCTGCCTCCTAGGCTGGAAGCCATGGTCCCGAAGTGTAGGGCAAGGGTGCCTCAGGACCTTTTGGTCTTCAGC CTCCCTCAGCCCCCAGGATCTGGGTTAGGTGGCCGCTCCTCCCTGCTCCTCATGGGAAGATGTCTCAGAGCCTTCCATGACCTCCCCTCC CCAGCCCAATGCCAAGTGGACTTGGAGCTGCACAAAGTCAGCAGGGACCACTAAATCTCCAAGACCTGGTGTGCGGAGGCAGGAGCATGT ATGTCTGCAGGTGTCTGACACGCAAGTGTGTGAGTGTGAGTGTGAGAGATGGGGCGGGGGTGTGTCTGTAGGTGTCTCTGGGCCTGTGTG TGGGTGGGGTTATGTGAGGGTATGAAGAGCTGTCTTCCCCTGAGAGTTTCCTCACTTACATAAAGCTCCCTTGAAGCAAGAAAGAGGGTC CCAGGGCTGCAAAACTGGAAGCACAGCCTCGGGGATGGGGAGGGAAAGACGGTGCTATATCCAGTTCCTGCTCTCTGCTCATGGGTGGCT GTGACAACCCTGGCCTCACTTGATTCATCTCTGGTTTTCTTGCCACCCTCTGGGAGTCCCCATCCCATTTTCATCCTGAGCCCAACCAGG CCCTGCCATTGGCCTCTTGTCCCTTGGCACACTTGTACCCACAGGTGAGGGGCAGGACCTGAAGGTATTGGCCTGTTCAACAATCAGTCA TCATGGGTGTTTTTGTCAACTGCTTGTTAATTGATTTGGGGATGTTTGCCCCGAATGAGAGGTTGAGGAAAAGACTGTGGGTGGGGAGGC CCTGCCTGACCCATCCCTTTTCCTTTCTGGCCCCAGCCTAGGTGGAGGCAAGTGGAATATCTTATATTGGGCGATTTGGGGGCTCGGGGA GGCAGAGAATCTCTTGGGAGTCTTGGGTGGCGCTGGTGCATTCTGTTTCCTCTTGATCTCAAAGCACAATGTGGATTTGGGGACCAAAGG TCAGGGACACATCCCCTTAGAGGACCTGAGTTTGGGAGAGTGGTGAGTGGAAGGGAGGAGCAGCAAGAAGCAGCCTGTTTTCACTCAGCT TAATTCTCCTTCCCAGATAAGGCAAGCCAGTCATGGAATCTTGCTGCAGGCCCTCCCTCTACTCTTCCTGTCCTAAAAATAGGGGCCGTT TTCTTACACACCCCCAGAGAGAGGAGGGACTGTCACACTGGTGCTGAGTGACCGGGGGCTGCTGGGCGTCTGTTCTTTACCAAAACCATC CATCCCTAGAAGAGCACAGAGCCCTGAGGGGCTGGGCTGGGCTGGGCTGAGCCCCTGGTCTTCTCTACAGTTCACAGAGGTCTTTCAGCT CATTTAATCCCAGGAAAGAGGCATCAAAGCTAGAATGTGAATATAACTTTTGTGGACCAATACTAAGAATAACAAGAAGCCCAGTGGTGA GGAAAGTGCGTTCTCCCAGCACTGCCTCCTGTTTTCTCCCTCTCATGTCCCTCCAGGGAAAATGACTTTATTGCTTAATTTCTGCCTTTC CCCCCTCACACATGCACTTTTGGGCCTTTTTTTATAGCTGGAAAAAACAAAATACCACCCTACAAACCTGTATTTAAAAAGAAACAGAAA TGACCACGTGAAATTTGCCTCTGTCCAAACATTTCATCCGTGTGTATGTGTATGTGTGTGAGTGTGTGAAGCCGCCAGTTCATCTTTTTA TATGGGGTTGTTGTCTCATTTTGGTCTGTTTTGGTCCCCTCCCTCGTGGGCTTGTGCTCGGGATCAAACCTTTCTGGCCTGTTATGATTC >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_3907nt AGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAGC TGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGGC CGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAG GTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCC AACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTC CAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAG GGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGT GCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGC AGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGAC ACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTAC GTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCTT CAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCACT TCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGGA GGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCACA TACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCTT GGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCCC ACCTGGGGTCTCTCTCCCTACCTCCCTCCTCAGGGGCAACAACAGGAGAATGGGGTTCCTGCTGTGGGGCGAATTCATCCCCTCCCCGCG CGTTCCTTCGCACACTGTGATTTTGCCCTCCTGCCCACGCAGACCTGCAGCGGGCAAAGAGCTCCCGAGGAAGCACAGCTTGGGTCAGGT TCTTGCCTTTCTTAATTTTAGGGACAGCTACCGGAAGGAGGGGAACAAGGAGTTCTCTTCCGCAGCCCCTTTCCCCACGCCCACCCCCAG TCTCCAGGGACCCTTGCCTGCCTCCTAGGCTGGAAGCCATGGTCCCGAAGTGTAGGGCAAGGGTGCCTCAGGACCTTTTGGTCTTCAGCC TCCCTCAGCCCCCAGGATCTGGGTTAGGTGGCCGCTCCTCCCTGCTCCTCATGGGAAGATGTCTCAGAGCCTTCCATGACCTCCCCTCCC CAGCCCAATGCCAAGTGGACTTGGAGCTGCACAAAGTCAGCAGGGACCACTAAATCTCCAAGACCTGGTGTGCGGAGGCAGGAGCATGTA TGTCTGCAGGTGTCTGACACGCAAGTGTGTGAGTGTGAGTGTGAGAGATGGGGCGGGGGTGTGTCTGTAGGTGTCTCTGGGCCTGTGTGT GGGTGGGGTTATGTGAGGGTATGAAGAGCTGTCTTCCCCTGAGAGTTTCCTCAGAACCCACAGTGAGAGGGGAGGGCTCCTGGGGCAGAG AAGTTCCTTAGGTTTTCTTTGGAATGAAATTCCTCCTTCCCCCCATCTCTGAGTGGAGGAAGCCCACCAATCTGCCCTTTGCAGTGTGCA GGGTGGAAGGTAAGAGGTTGGTGTGGAGTTGGGGCTGCCATAGGGTCTGCAGCCTGCTGGGGCTAAGCGGTGGAGGAAGGCTCTGTCACT CCAGGCATATGTTTCCCCATCTCTGTCTGGGGCTACAGAATAGGGTGGCAGAAGTGTCACCCTGTGGGTGTCTCCCTCGGGGGCTCTTCC CCTAGACCTCCCCCTCACTTACATAAAGCTCCCTTGAAGCAAGAAAGAGGGTCCCAGGGCTGCAAAACTGGAAGCACAGCCTCGGGGATG GGGAGGGAAAGACGGTGCTATATCCAGTTCCTGCTCTCTGCTCATGGGTGGCTGTGACAACCCTGGCCTCACTTGATTCATCTCTGGTTT TCTTGCCACCCTCTGGGAGTCCCCATCCCATTTTCATCCTGAGCCCAACCAGGCCCTGCCATTGGCCTCTTGTCCCTTGGCACACTTGTA CCCACAGGTGAGGGGCAGGACCTGAAGGTATTGGCCTGTTCAACAATCAGTCATCATGGGTGTTTTTGTCAACTGCTTGTTAATTGATTT GGGGATGTTTGCCCCGAATGAGAGGTTGAGGAAAAGACTGTGGGTGGGGAGGCCCTGCCTGACCCATCCCTTTTCCTTTCTGGCCCCAGC CTAGGTGGAGGCAAGTGGAATATCTTATATTGGGCGATTTGGGGGCTCGGGGAGGCAGAGAATCTCTTGGGAGTCTTGGGTGGCGCTGGT GCATTCTGTTTCCTCTTGATCTCAAAGCACAATGTGGATTTGGGGACCAAAGGTCAGGGACACATCCCCTTAGAGGACCTGAGTTTGGGA GAGTGGTGAGTGGAAGGGAGGAGCAGCAAGAAGCAGCCTGTTTTCACTCAGCTTAATTCTCCTTCCCAGATAAGGCAAGCCAGTCATGGA ATCTTGCTGCAGGCCCTCCCTCTACTCTTCCTGTCCTAAAAATAGGGGCCGTTTTCTTACACACCCCCAGAGAGAGGAGGGACTGTCACA CTGGTGCTGAGTGACCGGGGGCTGCTGGGCGTCTGTTCTTTACCAAAACCATCCATCCCTAGAAGAGCACAGAGCCCTGAGGGGCTGGGC TGGGCTGGGCTGAGCCCCTGGTCTTCTCTACAGTTCACAGAGGTCTTTCAGCTCATTTAATCCCAGGAAAGAGGCATCAAAGCTAGAATG TGAATATAACTTTTGTGGACCAATACTAAGAATAACAAGAAGCCCAGTGGTGAGGAAAGTGCGTTCTCCCAGCACTGCCTCCTGTTTTCT CCCTCTCATGTCCCTCCAGGGAAAATGACTTTATTGCTTAATTTCTGCCTTTCCCCCCTCACACATGCACTTTTGGGCCTTTTTTTATAG CTGGAAAAAACAAAATACCACCCTACAAACCTGTATTTAAAAAGAAACAGAAATGACCACGTGAAATTTGCCTCTGTCCAAACATTTCAT CCGTGTGTATGTGTATGTGTGTGAGTGTGTGAAGCCGCCAGTTCATCTTTTTATATGGGGTTGTTGTCTCATTTTGGTCTGTTTTGGTCC CCTCCCTCGTGGGCTTGTGCTCGGGATCAAACCTTTCTGGCCTGTTATGATTCTGAACATTTGACTTGAACCACAAGTGAATCTTTCTCC >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_1463nt AGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAGC TGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGGC CGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAG GTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCC AACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTC CAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAG GGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGT GCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGC AGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGAC ACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTAC GTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCTT CAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCACT TCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGGA GGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCACA TACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCTT GGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCCC >In-frame_CACNB1_ENST00000394310_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_3574nt AGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAGC TGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGGC CGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGAG GTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCC AACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCTC CAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGAG GGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAGT GCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCGC AGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGAC ACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTAC GTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCTT CAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCACT TCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGGA GGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCACA TACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCTT GGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCCC ACCTGGGGTCTCTCTCCCTACCTCCCTCCTCAGGGGCAACAACAGGAGAATGGGGTTCCTGCTGTGGGGCGAATTCATCCCCTCCCCGCG CGTTCCTTCGCACACTGTGATTTTGCCCTCCTGCCCACGCAGACCTGCAGCGGGCAAAGAGCTCCCGAGGAAGCACAGCTTGGGTCAGGT TCTTGCCTTTCTTAATTTTAGGGACAGCTACCGGAAGGAGGGGAACAAGGAGTTCTCTTCCGCAGCCCCTTTCCCCACGCCCACCCCCAG TCTCCAGGGACCCTTGCCTGCCTCCTAGGCTGGAAGCCATGGTCCCGAAGTGTAGGGCAAGGGTGCCTCAGGACCTTTTGGTCTTCAGCC TCCCTCAGCCCCCAGGATCTGGGTTAGGTGGCCGCTCCTCCCTGCTCCTCATGGGAAGATGTCTCAGAGCCTTCCATGACCTCCCCTCCC CAGCCCAATGCCAAGTGGACTTGGAGCTGCACAAAGTCAGCAGGGACCACTAAATCTCCAAGACCTGGTGTGCGGAGGCAGGAGCATGTA TGTCTGCAGGTGTCTGACACGCAAGTGTGTGAGTGTGAGTGTGAGAGATGGGGCGGGGGTGTGTCTGTAGGTGTCTCTGGGCCTGTGTGT GGGTGGGGTTATGTGAGGGTATGAAGAGCTGTCTTCCCCTGAGAGTTTCCTCACTTACATAAAGCTCCCTTGAAGCAAGAAAGAGGGTCC CAGGGCTGCAAAACTGGAAGCACAGCCTCGGGGATGGGGAGGGAAAGACGGTGCTATATCCAGTTCCTGCTCTCTGCTCATGGGTGGCTG TGACAACCCTGGCCTCACTTGATTCATCTCTGGTTTTCTTGCCACCCTCTGGGAGTCCCCATCCCATTTTCATCCTGAGCCCAACCAGGC CCTGCCATTGGCCTCTTGTCCCTTGGCACACTTGTACCCACAGGTGAGGGGCAGGACCTGAAGGTATTGGCCTGTTCAACAATCAGTCAT CATGGGTGTTTTTGTCAACTGCTTGTTAATTGATTTGGGGATGTTTGCCCCGAATGAGAGGTTGAGGAAAAGACTGTGGGTGGGGAGGCC CTGCCTGACCCATCCCTTTTCCTTTCTGGCCCCAGCCTAGGTGGAGGCAAGTGGAATATCTTATATTGGGCGATTTGGGGGCTCGGGGAG GCAGAGAATCTCTTGGGAGTCTTGGGTGGCGCTGGTGCATTCTGTTTCCTCTTGATCTCAAAGCACAATGTGGATTTGGGGACCAAAGGT CAGGGACACATCCCCTTAGAGGACCTGAGTTTGGGAGAGTGGTGAGTGGAAGGGAGGAGCAGCAAGAAGCAGCCTGTTTTCACTCAGCTT AATTCTCCTTCCCAGATAAGGCAAGCCAGTCATGGAATCTTGCTGCAGGCCCTCCCTCTACTCTTCCTGTCCTAAAAATAGGGGCCGTTT TCTTACACACCCCCAGAGAGAGGAGGGACTGTCACACTGGTGCTGAGTGACCGGGGGCTGCTGGGCGTCTGTTCTTTACCAAAACCATCC ATCCCTAGAAGAGCACAGAGCCCTGAGGGGCTGGGCTGGGCTGGGCTGAGCCCCTGGTCTTCTCTACAGTTCACAGAGGTCTTTCAGCTC ATTTAATCCCAGGAAAGAGGCATCAAAGCTAGAATGTGAATATAACTTTTGTGGACCAATACTAAGAATAACAAGAAGCCCAGTGGTGAG GAAAGTGCGTTCTCCCAGCACTGCCTCCTGTTTTCTCCCTCTCATGTCCCTCCAGGGAAAATGACTTTATTGCTTAATTTCTGCCTTTCC CCCCTCACACATGCACTTTTGGGCCTTTTTTTATAGCTGGAAAAAACAAAATACCACCCTACAAACCTGTATTTAAAAAGAAACAGAAAT GACCACGTGAAATTTGCCTCTGTCCAAACATTTCATCCGTGTGTATGTGTATGTGTGTGAGTGTGTGAAGCCGCCAGTTCATCTTTTTAT ATGGGGTTGTTGTCTCATTTTGGTCTGTTTTGGTCCCCTCCCTCGTGGGCTTGTGCTCGGGATCAAACCTTTCTGGCCTGTTATGATTCT >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000318008_chr17_37054665_+_3908nt GAGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAG CTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGG CCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGA GGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATC CAACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCT CCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGA GGGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAG TGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCG CAGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGA CACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTA CGTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCT TCAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCAC TTCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGG AGGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCAC ATACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCT TGGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCC CACCTGGGGTCTCTCTCCCTACCTCCCTCCTCAGGGGCAACAACAGGAGAATGGGGTTCCTGCTGTGGGGCGAATTCATCCCCTCCCCGC GCGTTCCTTCGCACACTGTGATTTTGCCCTCCTGCCCACGCAGACCTGCAGCGGGCAAAGAGCTCCCGAGGAAGCACAGCTTGGGTCAGG TTCTTGCCTTTCTTAATTTTAGGGACAGCTACCGGAAGGAGGGGAACAAGGAGTTCTCTTCCGCAGCCCCTTTCCCCACGCCCACCCCCA GTCTCCAGGGACCCTTGCCTGCCTCCTAGGCTGGAAGCCATGGTCCCGAAGTGTAGGGCAAGGGTGCCTCAGGACCTTTTGGTCTTCAGC CTCCCTCAGCCCCCAGGATCTGGGTTAGGTGGCCGCTCCTCCCTGCTCCTCATGGGAAGATGTCTCAGAGCCTTCCATGACCTCCCCTCC CCAGCCCAATGCCAAGTGGACTTGGAGCTGCACAAAGTCAGCAGGGACCACTAAATCTCCAAGACCTGGTGTGCGGAGGCAGGAGCATGT ATGTCTGCAGGTGTCTGACACGCAAGTGTGTGAGTGTGAGTGTGAGAGATGGGGCGGGGGTGTGTCTGTAGGTGTCTCTGGGCCTGTGTG TGGGTGGGGTTATGTGAGGGTATGAAGAGCTGTCTTCCCCTGAGAGTTTCCTCAGAACCCACAGTGAGAGGGGAGGGCTCCTGGGGCAGA GAAGTTCCTTAGGTTTTCTTTGGAATGAAATTCCTCCTTCCCCCCATCTCTGAGTGGAGGAAGCCCACCAATCTGCCCTTTGCAGTGTGC AGGGTGGAAGGTAAGAGGTTGGTGTGGAGTTGGGGCTGCCATAGGGTCTGCAGCCTGCTGGGGCTAAGCGGTGGAGGAAGGCTCTGTCAC TCCAGGCATATGTTTCCCCATCTCTGTCTGGGGCTACAGAATAGGGTGGCAGAAGTGTCACCCTGTGGGTGTCTCCCTCGGGGGCTCTTC CCCTAGACCTCCCCCTCACTTACATAAAGCTCCCTTGAAGCAAGAAAGAGGGTCCCAGGGCTGCAAAACTGGAAGCACAGCCTCGGGGAT GGGGAGGGAAAGACGGTGCTATATCCAGTTCCTGCTCTCTGCTCATGGGTGGCTGTGACAACCCTGGCCTCACTTGATTCATCTCTGGTT TTCTTGCCACCCTCTGGGAGTCCCCATCCCATTTTCATCCTGAGCCCAACCAGGCCCTGCCATTGGCCTCTTGTCCCTTGGCACACTTGT ACCCACAGGTGAGGGGCAGGACCTGAAGGTATTGGCCTGTTCAACAATCAGTCATCATGGGTGTTTTTGTCAACTGCTTGTTAATTGATT TGGGGATGTTTGCCCCGAATGAGAGGTTGAGGAAAAGACTGTGGGTGGGGAGGCCCTGCCTGACCCATCCCTTTTCCTTTCTGGCCCCAG CCTAGGTGGAGGCAAGTGGAATATCTTATATTGGGCGATTTGGGGGCTCGGGGAGGCAGAGAATCTCTTGGGAGTCTTGGGTGGCGCTGG TGCATTCTGTTTCCTCTTGATCTCAAAGCACAATGTGGATTTGGGGACCAAAGGTCAGGGACACATCCCCTTAGAGGACCTGAGTTTGGG AGAGTGGTGAGTGGAAGGGAGGAGCAGCAAGAAGCAGCCTGTTTTCACTCAGCTTAATTCTCCTTCCCAGATAAGGCAAGCCAGTCATGG AATCTTGCTGCAGGCCCTCCCTCTACTCTTCCTGTCCTAAAAATAGGGGCCGTTTTCTTACACACCCCCAGAGAGAGGAGGGACTGTCAC ACTGGTGCTGAGTGACCGGGGGCTGCTGGGCGTCTGTTCTTTACCAAAACCATCCATCCCTAGAAGAGCACAGAGCCCTGAGGGGCTGGG CTGGGCTGGGCTGAGCCCCTGGTCTTCTCTACAGTTCACAGAGGTCTTTCAGCTCATTTAATCCCAGGAAAGAGGCATCAAAGCTAGAAT GTGAATATAACTTTTGTGGACCAATACTAAGAATAACAAGAAGCCCAGTGGTGAGGAAAGTGCGTTCTCCCAGCACTGCCTCCTGTTTTC TCCCTCTCATGTCCCTCCAGGGAAAATGACTTTATTGCTTAATTTCTGCCTTTCCCCCCTCACACATGCACTTTTGGGCCTTTTTTTATA GCTGGAAAAAACAAAATACCACCCTACAAACCTGTATTTAAAAAGAAACAGAAATGACCACGTGAAATTTGCCTCTGTCCAAACATTTCA TCCGTGTGTATGTGTATGTGTGTGAGTGTGTGAAGCCGCCAGTTCATCTTTTTATATGGGGTTGTTGTCTCATTTTGGTCTGTTTTGGTC CCCTCCCTCGTGGGCTTGTGCTCGGGATCAAACCTTTCTGGCCTGTTATGATTCTGAACATTTGACTTGAACCACAAGTGAATCTTTCTC >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000433206_chr17_37054665_+_1464nt GAGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAG CTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGG CCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGA GGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATC CAACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCT CCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGA GGGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAG TGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCG CAGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGA CACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTA CGTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCT TCAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCAC TTCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGG AGGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCAC ATACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCT TGGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCC >In-frame_CACNB1_ENST00000344140_chr17_37351137_-_LASP1_ENST00000435347_chr17_37054665_+_3575nt GAGATGCTGAGCCTACGGGGGAGGCGGCGGCGGCAGTGGAGAGAGCGGGAGGAGCGAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAG CTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGG CCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGGA GGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATC CAACAGCTTTGTCCGCCAGGTGCGCTACAAGGAGGAGTTTGAGAAGAACAAGGGCAAAGGTTTCAGCGTAGTGGCAGACACGCCCGAGCT CCAGAGAATCAAGAAGACCCAGGACCAGATCAGTAACATAAAATACCATGAGGAGTTTGAGAAGAGCCGCATGGGCCCTAGCGGGGGCGA GGGCATGGAGCCAGAGCGTCGGGATTCACAGGACGGCAGCAGCTACCGGCGGCCCCTGGAGCAGCAGCAGCCTCACCACATCCCGACCAG TGCCCCGGTTTACCAGCAGCCCCAGCAGCAGCCGGTGGCCCAGTCCTATGGTGGCTACAAGGAGCCTGCAGCCCCAGTCTCCATACAGCG CAGCGCCCCAGGTGGTGGCGGGAAGCGGTACCGCGCGGTGTATGACTACAGCGCCGCCGACGAGGACGAGGTCTCCTTCCAGGACGGGGA CACCATCGTCAACGTGCAGCAGATCGACGACGGCTGGATGTACGGGACGGTGGAGCGCACCGGCGACACGGGGATGCTGCCGGCCAACTA CGTGGAGGCCATCTGAACCCGCAGCGCCCCCATCTGTCTTCAGCACATTCCACGGCATCGCATCCGTCCTGGGCGTGACCCGTCCATTCT TCAGTGTCTCTGTTTTTTAAAACCTGCGACAGCTTGTGATTCCTACCCCTCTTCCAGCTTCTTTTGCCAACTGAAGCCTTCTTCTGCCAC TTCTGCGGGCTCCCTCCTCTGGCAGGCTTCCCCCTTGATCGACTTCTTGGTTTTCTCTCTGGATGGAACGGGCATGGGCCTCTCTGGGGG AGGCAGGGCTGGAATGGGAGACCTGTTGGCCTGTGGGCCTCACCTGCCCCTCTGTTCTCTCCCCTCACATCCTCCTGCCCAGCTCCTCAC ATACCCACACATTCCAGGGCTGGGGTGAGCCTGACTGCCAGGACCCCAGGTCAGGGGCTCCCTACATTCCCCAGAGTGGGATCCACTTCT TGGTTCCTGGGATGGCGATGGGGACTCTGCCGCTGTGTAGGGACCAGTGGGATGGGCTCTACCTCTCTTTCTCAAAGAGGGGGCTCTGCC CACCTGGGGTCTCTCTCCCTACCTCCCTCCTCAGGGGCAACAACAGGAGAATGGGGTTCCTGCTGTGGGGCGAATTCATCCCCTCCCCGC GCGTTCCTTCGCACACTGTGATTTTGCCCTCCTGCCCACGCAGACCTGCAGCGGGCAAAGAGCTCCCGAGGAAGCACAGCTTGGGTCAGG TTCTTGCCTTTCTTAATTTTAGGGACAGCTACCGGAAGGAGGGGAACAAGGAGTTCTCTTCCGCAGCCCCTTTCCCCACGCCCACCCCCA GTCTCCAGGGACCCTTGCCTGCCTCCTAGGCTGGAAGCCATGGTCCCGAAGTGTAGGGCAAGGGTGCCTCAGGACCTTTTGGTCTTCAGC CTCCCTCAGCCCCCAGGATCTGGGTTAGGTGGCCGCTCCTCCCTGCTCCTCATGGGAAGATGTCTCAGAGCCTTCCATGACCTCCCCTCC CCAGCCCAATGCCAAGTGGACTTGGAGCTGCACAAAGTCAGCAGGGACCACTAAATCTCCAAGACCTGGTGTGCGGAGGCAGGAGCATGT ATGTCTGCAGGTGTCTGACACGCAAGTGTGTGAGTGTGAGTGTGAGAGATGGGGCGGGGGTGTGTCTGTAGGTGTCTCTGGGCCTGTGTG TGGGTGGGGTTATGTGAGGGTATGAAGAGCTGTCTTCCCCTGAGAGTTTCCTCACTTACATAAAGCTCCCTTGAAGCAAGAAAGAGGGTC CCAGGGCTGCAAAACTGGAAGCACAGCCTCGGGGATGGGGAGGGAAAGACGGTGCTATATCCAGTTCCTGCTCTCTGCTCATGGGTGGCT GTGACAACCCTGGCCTCACTTGATTCATCTCTGGTTTTCTTGCCACCCTCTGGGAGTCCCCATCCCATTTTCATCCTGAGCCCAACCAGG CCCTGCCATTGGCCTCTTGTCCCTTGGCACACTTGTACCCACAGGTGAGGGGCAGGACCTGAAGGTATTGGCCTGTTCAACAATCAGTCA TCATGGGTGTTTTTGTCAACTGCTTGTTAATTGATTTGGGGATGTTTGCCCCGAATGAGAGGTTGAGGAAAAGACTGTGGGTGGGGAGGC CCTGCCTGACCCATCCCTTTTCCTTTCTGGCCCCAGCCTAGGTGGAGGCAAGTGGAATATCTTATATTGGGCGATTTGGGGGCTCGGGGA GGCAGAGAATCTCTTGGGAGTCTTGGGTGGCGCTGGTGCATTCTGTTTCCTCTTGATCTCAAAGCACAATGTGGATTTGGGGACCAAAGG TCAGGGACACATCCCCTTAGAGGACCTGAGTTTGGGAGAGTGGTGAGTGGAAGGGAGGAGCAGCAAGAAGCAGCCTGTTTTCACTCAGCT TAATTCTCCTTCCCAGATAAGGCAAGCCAGTCATGGAATCTTGCTGCAGGCCCTCCCTCTACTCTTCCTGTCCTAAAAATAGGGGCCGTT TTCTTACACACCCCCAGAGAGAGGAGGGACTGTCACACTGGTGCTGAGTGACCGGGGGCTGCTGGGCGTCTGTTCTTTACCAAAACCATC CATCCCTAGAAGAGCACAGAGCCCTGAGGGGCTGGGCTGGGCTGGGCTGAGCCCCTGGTCTTCTCTACAGTTCACAGAGGTCTTTCAGCT CATTTAATCCCAGGAAAGAGGCATCAAAGCTAGAATGTGAATATAACTTTTGTGGACCAATACTAAGAATAACAAGAAGCCCAGTGGTGA GGAAAGTGCGTTCTCCCAGCACTGCCTCCTGTTTTCTCCCTCTCATGTCCCTCCAGGGAAAATGACTTTATTGCTTAATTTCTGCCTTTC CCCCCTCACACATGCACTTTTGGGCCTTTTTTTATAGCTGGAAAAAACAAAATACCACCCTACAAACCTGTATTTAAAAAGAAACAGAAA TGACCACGTGAAATTTGCCTCTGTCCAAACATTTCATCCGTGTGTATGTGTATGTGTGTGAGTGTGTGAAGCCGCCAGTTCATCTTTTTA TATGGGGTTGTTGTCTCATTTTGGTCTGTTTTGGTCCCCTCCCTCGTGGGCTTGTGCTCGGGATCAAACCTTTCTGGCCTGTTATGATTC |
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FusionGenePPI for CACNB1_LASP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CACNB1 | NEDD4L, ATN1, APP, SRPK1, CACNB2, CACNB3, C19orf26, KLHL15, WDR75 | LASP1 | TRIP13, PLSCR1, FHL3, MDFI, ZYX, TERF1, TINF2, ACD, POT1, ATXN1, FN1, DAZAP2, CD81, GOLGA2, PSMA3, REL, TRIM27, TCF4, FXR2, SPRY2, ARHGEF15, ZC2HC1A, THAP1, SEPT3, LZTS2, RHOXF2, KRTAP4-2, ZBTB9, ZDHHC17, CCDC8, ILK, HAX1, DNAAF2, THAP8, FYTTD1, NFYA, OR10H3, RDH12, SLC25A32, SLC25A44, C11orf65, TAS2R41, AHNAK, ARFGAP1, DDB1, EIF4B, HSPB1, HSPE1, LGALS1, MAP4, NXF1, CRK, STAT3, SH2D2A, CEP170, FBF1, SCLT1, DCTN1, U2AF2, CDH1, ZNF764, SNRNP27, PGK1, EZR, SPTAN1, NCL, UHRF1, NAT10, PDIA5, API5, KRT18, KRT2, G3BP2, AP3M1, NCOR2, CDK12, MYO1C, ACTR3, CLTC, DNMT1, EHMT2, SNAI1, HIST1H3A, TRIM25, TES |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CACNB1_LASP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | CACNB1 | Q02641 | DB00308 | Ibutilide | Voltage-dependent L-type calcium channel subunit beta-1 | small molecule | approved |
| Hgene | CACNB1 | Q02641 | DB00661 | Verapamil | Voltage-dependent L-type calcium channel subunit beta-1 | small molecule | approved |
| Hgene | CACNB1 | Q02641 | DB00898 | Ethanol | Voltage-dependent L-type calcium channel subunit beta-1 | small molecule | approved |
| Hgene | CACNB1 | Q02641 | DB04855 | Dronedarone | Voltage-dependent L-type calcium channel subunit beta-1 | small molecule | approved |
| Hgene | CACNB1 | Q02641 | DB00393 | Nimodipine | Voltage-dependent L-type calcium channel subunit beta-1 | small molecule | approved|investigational |
| Hgene | CACNB1 | Q02641 | DB00653 | Magnesium sulfate | Voltage-dependent L-type calcium channel subunit beta-1 | small molecule | approved|investigational|vet_approved |
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RelatedDiseases for CACNB1_LASP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | LASP1 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Tgene | LASP1 | C0036341 | Schizophrenia | 1 | PSYGENET |
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