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Fusion gene ID: 4911 |
FusionGeneSummary for C21orf59_URB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: C21orf59_URB1 | Fusion gene ID: 4911 | Hgene | Tgene | Gene symbol | C21orf59 | URB1 | Gene ID | 9875 |
| Gene name | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) | ||
| Synonyms | C21orf108|NPA1 | ||
| Cytomap | 21q22.11 | ||
| Type of gene | protein-coding | ||
| Description | nucleolar pre-ribosomal-associated protein 1nucleolar preribosomal-associated protein 1nucleolar protein 254 kDa | ||
| Modification date | 20180519 | ||
| UniProtAcc | O60287 | ||
| Ensembl transtripts involved in fusion gene | ENST00000382549, ENST00000290155, ENST00000540881, | ENST00000382751, ENST00000492603, | |
| Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 1 X 1 X 1=1 |
| # samples | 3 | 1 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: C21orf59 [Title/Abstract] AND URB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | STAD | TCGA-BR-8373-01A | C21orf59 | chr21 | 33979959 | - | URB1 | chr21 | 33750850 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000382549 | ENST00000382751 | C21orf59 | chr21 | 33979959 | - | URB1 | chr21 | 33750850 | - |
| 5CDS-intron | ENST00000382549 | ENST00000492603 | C21orf59 | chr21 | 33979959 | - | URB1 | chr21 | 33750850 | - |
| In-frame | ENST00000290155 | ENST00000382751 | C21orf59 | chr21 | 33979959 | - | URB1 | chr21 | 33750850 | - |
| 5CDS-intron | ENST00000290155 | ENST00000492603 | C21orf59 | chr21 | 33979959 | - | URB1 | chr21 | 33750850 | - |
| In-frame | ENST00000540881 | ENST00000382751 | C21orf59 | chr21 | 33979959 | - | URB1 | chr21 | 33750850 | - |
| 5CDS-intron | ENST00000540881 | ENST00000492603 | C21orf59 | chr21 | 33979959 | - | URB1 | chr21 | 33750850 | - |
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FusionProtFeatures for C21orf59_URB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| C21orf59 | URB1 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for C21orf59_URB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_C21orf59_ENST00000382549_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_2208aa MVLLHVKRGDESQFLLQAPGSTELEELTVQVARVYNGRLKVQRLCSEMEELAEHGIFLPPNMQGLTDDQIEELKLKDEWGEKCVPSGGAV FKKDDIGRRNGQAPNEKMKQVLKKTIEEAKAIISKGVYDVRQAYVQFALSFLIAGDDSTIVQVLEVKEFIPCIFSSGIKEDRISTINILL STLKTKVVHNKNITKTQKVRFFTGQLLNHIASLYNWNGITDVNPENVKVSAEEAGKTMVRELVHNFLMDLCCSLKHGINFYDASLGTFGR GGNLTLLHFLLGLKTAADDDLVADLVVNILKVCPDLLNKYFKEVTFSFIPRAKSTWLNNIKLLNKIYEAQPEISRAFQTREFIPLPRLLA MVMVTTVPLVCNKSMFTQALNLDSTSVRHTALSLISVILKRALKTVDHCLNKEVWQESGVYTAVMMEEFVQLFREALSKILPDLNTVVWV WQSLKKQETKQDDKKGQKRSDGPPAACDAHQCDDAETILLKAVLLQVICLYQKVVPHVVMQYNFDFSKLLKGVISEQGLREEVPPILQHH MLKVALELPASKFLWLKAQEGPDAEIIGGERSVFYLLMKMFVTSSHLQLKSLTKLLIMKILRDTGVFEHTWKELELWLEHLENTMEEDKE TVIQFLERILLTLVANPYSYTDKASDFVQEASMLQATMTKQEADDMSIPISHIDDVLDMVDVLVEGSEGLDEEIGFTLSEDMILLTFPFS AVVPAALEARNKLLLGTGNEAAENVVTYLTAVLTDLLHTQRDPLALCLLLQAYDKLEPPCLVPCCQQLSRFNRYYSLWIPEQAREAWLLQ AQGSPSPPALPLASSFTALLQAAYESQALRDEHIQVQLQATMPHLSMQQVLLAAKQVLLYLRSTVENFGQLGRSVGPPLLQLFLDLLRRL VVHCEQLDAQNQQRCEAARAEADLFLDMESVASLELANDQTLEEVLVAILRHPTLEGWFLALEQQALPPHTLSPVLVKLLATHFSAGVLQ LLAASAPILQNIGQLGLLARYSEAITQSVLKELQNRRAGPATSPPKTPPQLEALQELHPYMEGAQLREVTLALLSLPETHLVTQQPTKSP GKERHLNALGKTLVQLLTCSPQDQLQSGELLWSSEYVRGLGALLPTLAVDELDTVLLHTLQRDPVLAPAVGADLLDYCLARRTQAALSIA ALLLQESCTHLLWFEQWCLQAGPGLGLQGDLDDFLPLIHVYLQCRTRSHFTRPAGVSSAVIPVLRKTLWRQLQSRLLSTDSPPASGLYQE ILAQLVPFARAKDLSVLMDRLPSLLHTPSSHKRWIVADSISAALEGSAEELCAWRRTLLESCVKWLIVSFSGGQQDDDNTQNQEKEMLLR LNALLHALNEVDPGDWQKFVKKGLKFRYQDHTFLKMLLTAVQLLYSPESSVRTKLIQLPVVYVMLMQHSLFLPTLLTSDGEESPDSQVKE ALVDLMLTVVEMCPSVCESSHFAVLLGAYGATLSVLDQKILLLLRAYEQNKLSLINFRVLLWGPAAVEHHKTCRSLGRSLWQQPSVGDIL RLLDRDRMMQTILHFPQNRRLLPPEDTQELIFKDKSRVDLDGLYDPCFLLQLFSELTRPEFVVDCRKFLDSNALGLTVTALSSYDPQMRA IAYHVLAAYYSHLEGARFQEQSQLLYLLDVVRNGIRTQDMRLTFTLALFIAKAALQILKPEEHMYLKVSNFLLSHEYLNMDKVPGFYQFF YSSDFEQKTEQKWVFGVLRQGIRDKQCYELCARRGIFHIILSFFHSPLCDEAAQNWILEILQNAAQVARSAYEIIRDYSLLTWILHILES KFLETPLLSNVISLLHTLWVTNLGDKAVEWESQRLCQPSSQEPAKRLALHLVNEFLYVLIVLMKHLRPTLAPVQLTNFFGTLDSVLRYRA TVIQAFRDMNRFTVNETVLSTKDVLVLLHKWSLIERDLKLQEDLRAAIEKAQARELMKMLKDKNKPVMPARAKGPRGRKRRPGEAEEMAD PELMASTLETCKGLLRSILTYWRPVIPGPDPTQEPVDSASPESDAPGPVYAAASLAVSWVLRSVAEHPLSRAEAAGLIGWLKSHILPHPV VVADLLKDSAVRSSIFRLYSRLCGAEGLAGPVQEVACLFNTVMLQLVAAQGRAGSPFHPAMEALSLSSLSEKDEATQASAAFLVSLYIKD >In-frame_C21orf59_ENST00000290155_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_2208aa MVLLHVKRGDESQFLLQAPGSTELEELTVQVARVYNGRLKVQRLCSEMEELAEHGIFLPPNMQGLTDDQIEELKLKDEWGEKCVPSGGAV FKKDDIGRRNGQAPNEKMKQVLKKTIEEAKAIISKGVYDVRQAYVQFALSFLIAGDDSTIVQVLEVKEFIPCIFSSGIKEDRISTINILL STLKTKVVHNKNITKTQKVRFFTGQLLNHIASLYNWNGITDVNPENVKVSAEEAGKTMVRELVHNFLMDLCCSLKHGINFYDASLGTFGR GGNLTLLHFLLGLKTAADDDLVADLVVNILKVCPDLLNKYFKEVTFSFIPRAKSTWLNNIKLLNKIYEAQPEISRAFQTREFIPLPRLLA MVMVTTVPLVCNKSMFTQALNLDSTSVRHTALSLISVILKRALKTVDHCLNKEVWQESGVYTAVMMEEFVQLFREALSKILPDLNTVVWV WQSLKKQETKQDDKKGQKRSDGPPAACDAHQCDDAETILLKAVLLQVICLYQKVVPHVVMQYNFDFSKLLKGVISEQGLREEVPPILQHH MLKVALELPASKFLWLKAQEGPDAEIIGGERSVFYLLMKMFVTSSHLQLKSLTKLLIMKILRDTGVFEHTWKELELWLEHLENTMEEDKE TVIQFLERILLTLVANPYSYTDKASDFVQEASMLQATMTKQEADDMSIPISHIDDVLDMVDVLVEGSEGLDEEIGFTLSEDMILLTFPFS AVVPAALEARNKLLLGTGNEAAENVVTYLTAVLTDLLHTQRDPLALCLLLQAYDKLEPPCLVPCCQQLSRFNRYYSLWIPEQAREAWLLQ AQGSPSPPALPLASSFTALLQAAYESQALRDEHIQVQLQATMPHLSMQQVLLAAKQVLLYLRSTVENFGQLGRSVGPPLLQLFLDLLRRL VVHCEQLDAQNQQRCEAARAEADLFLDMESVASLELANDQTLEEVLVAILRHPTLEGWFLALEQQALPPHTLSPVLVKLLATHFSAGVLQ LLAASAPILQNIGQLGLLARYSEAITQSVLKELQNRRAGPATSPPKTPPQLEALQELHPYMEGAQLREVTLALLSLPETHLVTQQPTKSP GKERHLNALGKTLVQLLTCSPQDQLQSGELLWSSEYVRGLGALLPTLAVDELDTVLLHTLQRDPVLAPAVGADLLDYCLARRTQAALSIA ALLLQESCTHLLWFEQWCLQAGPGLGLQGDLDDFLPLIHVYLQCRTRSHFTRPAGVSSAVIPVLRKTLWRQLQSRLLSTDSPPASGLYQE ILAQLVPFARAKDLSVLMDRLPSLLHTPSSHKRWIVADSISAALEGSAEELCAWRRTLLESCVKWLIVSFSGGQQDDDNTQNQEKEMLLR LNALLHALNEVDPGDWQKFVKKGLKFRYQDHTFLKMLLTAVQLLYSPESSVRTKLIQLPVVYVMLMQHSLFLPTLLTSDGEESPDSQVKE ALVDLMLTVVEMCPSVCESSHFAVLLGAYGATLSVLDQKILLLLRAYEQNKLSLINFRVLLWGPAAVEHHKTCRSLGRSLWQQPSVGDIL RLLDRDRMMQTILHFPQNRRLLPPEDTQELIFKDKSRVDLDGLYDPCFLLQLFSELTRPEFVVDCRKFLDSNALGLTVTALSSYDPQMRA IAYHVLAAYYSHLEGARFQEQSQLLYLLDVVRNGIRTQDMRLTFTLALFIAKAALQILKPEEHMYLKVSNFLLSHEYLNMDKVPGFYQFF YSSDFEQKTEQKWVFGVLRQGIRDKQCYELCARRGIFHIILSFFHSPLCDEAAQNWILEILQNAAQVARSAYEIIRDYSLLTWILHILES KFLETPLLSNVISLLHTLWVTNLGDKAVEWESQRLCQPSSQEPAKRLALHLVNEFLYVLIVLMKHLRPTLAPVQLTNFFGTLDSVLRYRA TVIQAFRDMNRFTVNETVLSTKDVLVLLHKWSLIERDLKLQEDLRAAIEKAQARELMKMLKDKNKPVMPARAKGPRGRKRRPGEAEEMAD PELMASTLETCKGLLRSILTYWRPVIPGPDPTQEPVDSASPESDAPGPVYAAASLAVSWVLRSVAEHPLSRAEAAGLIGWLKSHILPHPV VVADLLKDSAVRSSIFRLYSRLCGAEGLAGPVQEVACLFNTVMLQLVAAQGRAGSPFHPAMEALSLSSLSEKDEATQASAAFLVSLYIKD >In-frame_C21orf59_ENST00000540881_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_2152aa MVLLHVKRGDESQFLLQAPGSTELEELTVQVARVYNGRLKVQRLCSAPNEKMKQVLKKTIEEAKAIISKGVYDVRQAYVQFALSFLIAGD DSTIVQVLEVKEFIPCIFSSGIKEDRISTINILLSTLKTKVVHNKNITKTQKVRFFTGQLLNHIASLYNWNGITDVNPENVKVSAEEAGK TMVRELVHNFLMDLCCSLKHGINFYDASLGTFGRGGNLTLLHFLLGLKTAADDDLVADLVVNILKVCPDLLNKYFKEVTFSFIPRAKSTW LNNIKLLNKIYEAQPEISRAFQTREFIPLPRLLAMVMVTTVPLVCNKSMFTQALNLDSTSVRHTALSLISVILKRALKTVDHCLNKEVWQ ESGVYTAVMMEEFVQLFREALSKILPDLNTVVWVWQSLKKQETKQDDKKGQKRSDGPPAACDAHQCDDAETILLKAVLLQVICLYQKVVP HVVMQYNFDFSKLLKGVISEQGLREEVPPILQHHMLKVALELPASKFLWLKAQEGPDAEIIGGERSVFYLLMKMFVTSSHLQLKSLTKLL IMKILRDTGVFEHTWKELELWLEHLENTMEEDKETVIQFLERILLTLVANPYSYTDKASDFVQEASMLQATMTKQEADDMSIPISHIDDV LDMVDVLVEGSEGLDEEIGFTLSEDMILLTFPFSAVVPAALEARNKLLLGTGNEAAENVVTYLTAVLTDLLHTQRDPLALCLLLQAYDKL EPPCLVPCCQQLSRFNRYYSLWIPEQAREAWLLQAQGSPSPPALPLASSFTALLQAAYESQALRDEHIQVQLQATMPHLSMQQVLLAAKQ VLLYLRSTVENFGQLGRSVGPPLLQLFLDLLRRLVVHCEQLDAQNQQRCEAARAEADLFLDMESVASLELANDQTLEEVLVAILRHPTLE GWFLALEQQALPPHTLSPVLVKLLATHFSAGVLQLLAASAPILQNIGQLGLLARYSEAITQSVLKELQNRRAGPATSPPKTPPQLEALQE LHPYMEGAQLREVTLALLSLPETHLVTQQPTKSPGKERHLNALGKTLVQLLTCSPQDQLQSGELLWSSEYVRGLGALLPTLAVDELDTVL LHTLQRDPVLAPAVGADLLDYCLARRTQAALSIAALLLQESCTHLLWFEQWCLQAGPGLGLQGDLDDFLPLIHVYLQCRTRSHFTRPAGV SSAVIPVLRKTLWRQLQSRLLSTDSPPASGLYQEILAQLVPFARAKDLSVLMDRLPSLLHTPSSHKRWIVADSISAALEGSAEELCAWRR TLLESCVKWLIVSFSGGQQDDDNTQNQEKEMLLRLNALLHALNEVDPGDWQKFVKKGLKFRYQDHTFLKMLLTAVQLLYSPESSVRTKLI QLPVVYVMLMQHSLFLPTLLTSDGEESPDSQVKEALVDLMLTVVEMCPSVCESSHFAVLLGAYGATLSVLDQKILLLLRAYEQNKLSLIN FRVLLWGPAAVEHHKTCRSLGRSLWQQPSVGDILRLLDRDRMMQTILHFPQNRRLLPPEDTQELIFKDKSRVDLDGLYDPCFLLQLFSEL TRPEFVVDCRKFLDSNALGLTVTALSSYDPQMRAIAYHVLAAYYSHLEGARFQEQSQLLYLLDVVRNGIRTQDMRLTFTLALFIAKAALQ ILKPEEHMYLKVSNFLLSHEYLNMDKVPGFYQFFYSSDFEQKTEQKWVFGVLRQGIRDKQCYELCARRGIFHIILSFFHSPLCDEAAQNW ILEILQNAAQVARSAYEIIRDYSLLTWILHILESKFLETPLLSNVISLLHTLWVTNLGDKAVEWESQRLCQPSSQEPAKRLALHLVNEFL YVLIVLMKHLRPTLAPVQLTNFFGTLDSVLRYRATVIQAFRDMNRFTVNETVLSTKDVLVLLHKWSLIERDLKLQEDLRAAIEKAQAREL MKMLKDKNKPVMPARAKGPRGRKRRPGEAEEMADPELMASTLETCKGLLRSILTYWRPVIPGPDPTQEPVDSASPESDAPGPVYAAASLA VSWVLRSVAEHPLSRAEAAGLIGWLKSHILPHPVVVADLLKDSAVRSSIFRLYSRLCGAEGLAGPVQEVACLFNTVMLQLVAAQGRAGSP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_C21orf59_ENST00000382549_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_6624nt ATGGTTCTGCTGCACGTGAAGCGGGGCGACGAGAGCCAGTTCCTGCTGCAGGCGCCTGGGAGTACCGAGCTGGAGGAGCTCACGGTGCAG GTGGCCCGGGTCTATAATGGGCGGCTCAAGGTGCAGCGCCTCTGCTCAGAAATGGAAGAATTAGCCGAACATGGCATATTTCTCCCTCCT AATATGCAAGGACTGACCGATGATCAGATTGAAGAATTGAAATTGAAGGATGAATGGGGTGAAAAATGCGTACCCAGCGGAGGTGCAGTG TTTAAAAAGGATGATATTGGACGAAGGAATGGGCAAGCTCCAAATGAGAAGATGAAGCAAGTGTTAAAGAAGACTATAGAAGAAGCCAAA GCAATAATATCTAAGGGAGTGTACGACGTTCGGCAGGCCTACGTTCAGTTTGCTCTCTCCTTTTTAATTGCGGGTGATGACAGCACTATA GTGCAGGTGTTGGAAGTGAAAGAATTTATTCCTTGCATTTTTAGCTCAGGGATAAAGGAAGATAGGATCTCTACCATCAATATTTTATTA TCCACACTGAAAACAAAGGTAGTTCACAATAAAAATATCACAAAAACCCAGAAGGTGCGTTTCTTTACGGGGCAGTTATTGAACCACATA GCATCGCTGTACAACTGGAATGGGATTACCGATGTGAACCCAGAAAATGTCAAGGTTTCTGCCGAAGAAGCAGGGAAAACCATGGTGCGG GAGCTTGTTCATAACTTCCTGATGGATCTTTGCTGTTCACTCAAGCATGGAATTAATTTTTACGATGCATCTTTGGGTACCTTTGGCAGA GGCGGAAACCTGACACTCTTGCACTTCTTGCTGGGTTTGAAAACTGCAGCTGATGATGATCTGGTGGCTGACCTTGTGGTAAACATCCTC AAAGTGTGCCCGGACTTACTGAACAAATACTTCAAGGAAGTAACGTTTTCCTTTATCCCACGAGCGAAGTCTACTTGGTTAAATAATATC AAACTACTAAACAAGATCTATGAGGCTCAGCCGGAGATTTCCCGGGCATTTCAGACCAGAGAGTTTATACCCTTGCCTCGGCTCCTGGCA ATGGTGATGGTGACCACCGTGCCCCTGGTGTGCAATAAGAGCATGTTCACCCAAGCATTAAACTTGGACAGCACCTCAGTGAGGCACACA GCCTTATCCCTTATTTCTGTCATTTTGAAGAGGGCATTAAAAACTGTTGACCACTGCCTGAATAAAGAGGTGTGGCAGGAATCAGGCGTG TACACAGCTGTGATGATGGAAGAATTCGTGCAGCTCTTCAGAGAAGCCCTGAGCAAGATTTTGCCAGACCTGAACACTGTCGTGTGGGTC TGGCAGTCACTTAAAAAGCAAGAGACCAAACAGGATGACAAGAAAGGGCAGAAAAGGAGCGATGGGCCCCCGGCTGCCTGCGATGCTCAC CAGTGCGATGATGCAGAAACCATTCTTTTGAAAGCTGTTTTGCTCCAGGTCATATGCCTCTACCAGAAGGTGGTCCCCCACGTGGTCATG CAGTACAACTTTGACTTCAGCAAGCTCCTGAAAGGTGTCATCTCTGAGCAGGGCCTTCGAGAGGAGGTGCCTCCCATTCTGCAGCACCAC ATGCTGAAGGTGGCCCTGGAGCTGCCGGCCAGCAAGTTTCTGTGGTTAAAGGCACAGGAAGGCCCAGATGCAGAAATTATTGGAGGTGAA CGATCAGTATTTTACTTACTAATGAAAATGTTTGTGACCAGTAGCCATTTACAACTGAAGTCATTGACCAAACTTCTGATCATGAAGATT CTGCGGGACACGGGGGTGTTTGAGCACACCTGGAAGGAGCTGGAGCTCTGGCTGGAGCATTTAGAGAACACCATGGAAGAGGACAAAGAG ACTGTGATTCAGTTTCTGGAACGCATTTTATTGACATTGGTGGCGAATCCCTATTCATACACAGACAAAGCATCTGACTTTGTCCAAGAA GCAAGCATGCTGCAGGCCACTATGACGAAGCAAGAAGCCGATGACATGAGCATTCCCATCTCCCACATTGACGATGTTCTCGACATGGTG GATGTCCTGGTGGAGGGCAGTGAAGGCTTGGATGAGGAAATAGGGTTCACGTTGAGTGAAGACATGATCCTGCTCACGTTCCCATTCAGT GCGGTAGTCCCTGCGGCCCTGGAAGCCAGGAATAAGTTGCTCCTTGGGACAGGCAATGAAGCAGCGGAAAACGTTGTGACATATCTGACG GCAGTGCTGACTGACCTCCTCCACACCCAGAGGGACCCCCTGGCTCTGTGTCTCCTGCTCCAGGCATATGATAAGCTTGAGCCTCCATGC CTGGTGCCTTGCTGCCAGCAGCTCTCACGGTTTAACAGATACTACAGCCTCTGGATCCCGGAGCAAGCCCGAGAGGCCTGGCTGCTGCAG GCACAGGGCAGCCCCTCGCCCCCTGCCCTTCCCTTGGCCTCGTCCTTCACAGCCCTGCTGCAGGCAGCCTACGAGAGCCAAGCGCTTCGG GACGAGCACATCCAGGTGCAGCTGCAGGCCACCATGCCACACCTGTCCATGCAGCAGGTCCTGCTCGCGGCCAAGCAGGTGTTGCTCTAC CTGCGGAGCACTGTGGAGAACTTCGGCCAGCTGGGCAGAAGTGTGGGCCCGCCCCTCCTGCAGCTCTTCCTGGATCTCCTCAGGCGCCTG GTTGTCCACTGTGAGCAGCTGGATGCCCAGAACCAGCAGAGATGCGAGGCCGCCCGGGCCGAAGCCGACCTCTTCCTGGACATGGAGTCC GTGGCCTCGCTGGAGTTGGCCAATGATCAGACGCTGGAGGAGGTGCTTGTGGCCATCCTCAGGCACCCCACCCTGGAGGGCTGGTTCCTG GCCCTGGAGCAGCAGGCCCTCCCGCCGCACACGCTCAGCCCTGTCCTCGTGAAGCTCCTGGCCACCCACTTTAGTGCAGGGGTCCTTCAG CTGCTGGCAGCAAGTGCCCCGATCCTCCAGAACATTGGGCAGCTGGGCCTTCTGGCCAGGTACTCAGAGGCCATCACCCAGAGTGTGCTG AAGGAACTTCAGAACAGGAGGGCGGGCCCGGCCACATCACCACCAAAGACCCCGCCGCAGCTGGAGGCCCTGCAGGAGCTGCATCCATAC ATGGAGGGTGCCCAGCTCCGTGAGGTCACCCTGGCCTTGCTGAGCCTGCCTGAGACACACCTGGTGACCCAGCAACCCACGAAATCCCCC GGGAAGGAAAGACACCTGAATGCTCTTGGAAAGACCCTGGTGCAGCTGCTGACCTGCAGCCCCCAGGATCAGCTGCAGAGTGGTGAGCTC CTGTGGTCCTCCGAGTATGTGAGAGGCCTGGGGGCTCTGCTGCCCACGCTAGCAGTGGACGAGCTGGACACAGTGCTCCTCCACACTCTG CAGAGAGACCCTGTGCTGGCCCCCGCAGTCGGGGCTGATCTGCTTGACTACTGCCTGGCCCGGCGCACACAGGCGGCCCTCAGCATCGCT GCCCTGCTCCTCCAGGAGAGCTGCACCCACTTGCTGTGGTTCGAGCAGTGGTGCCTGCAGGCTGGCCCAGGGCTCGGCCTCCAGGGGGAC CTGGACGACTTCCTTCCCCTCATCCATGTGTACCTCCAGTGCAGGACACGGAGCCACTTCACACGCCCAGCAGGAGTGTCTTCCGCTGTC ATTCCTGTCTTGAGGAAGACCCTGTGGAGGCAGCTACAGAGCAGGCTTCTTAGCACTGACAGTCCCCCAGCATCTGGGCTGTACCAGGAG ATCCTGGCACAGCTGGTCCCGTTTGCACGAGCCAAGGATCTCAGTGTACTCATGGACCGCCTGCCCAGCTTGCTTCACACCCCAAGCAGT CACAAGAGGTGGATCGTGGCCGACTCCATTTCAGCAGCTCTGGAAGGGTCAGCAGAAGAGCTGTGTGCCTGGAGAAGGACCCTTTTGGAG TCCTGTGTGAAGTGGCTGATCGTGTCTTTCAGTGGTGGACAGCAAGATGATGATAATACTCAGAATCAGGAGAAGGAAATGCTGCTTAGA TTAAATGCGTTGTTGCATGCACTTAATGAAGTTGATCCTGGTGACTGGCAGAAATTCGTGAAGAAGGGACTCAAATTTCGGTACCAGGAC CACACATTTTTAAAGATGCTCCTCACCGCCGTACAGCTCCTGTACAGCCCAGAAAGCTCCGTGCGCACGAAGCTCATCCAGCTCCCGGTG GTCTACGTGATGCTCATGCAGCACTCGCTGTTTCTGCCGACTCTACTGACGTCTGACGGAGAGGAGAGCCCGGACAGCCAAGTAAAAGAA GCGCTGGTGGACCTGATGCTGACGGTGGTGGAGATGTGCCCCTCTGTCTGTGAGAGCAGCCACTTTGCAGTGCTTCTCGGGGCCTATGGC GCCACTCTCAGCGTCCTAGATCAGAAGATTTTACTTCTGCTTCGAGCGTATGAGCAGAACAAGCTCAGCCTCATCAACTTCAGGGTGCTG CTGTGGGGCCCAGCGGCCGTGGAGCATCACAAGACGTGCCGGAGCCTGGGCAGGTCACTGTGGCAGCAGCCGAGTGTCGGGGACATCCTT CGCCTGCTGGACCGGGACCGGATGATGCAGACCATCCTGCACTTCCCCCAGAACCGGAGGCTGCTGCCCCCCGAGGACACACAGGAGCTG ATATTCAAAGACAAAAGCAGGGTGGATCTTGATGGCCTCTATGACCCCTGCTTTCTCCTTCAGCTCTTCAGTGAGCTGACCAGGCCAGAG TTTGTGGTGGATTGTCGAAAATTTTTGGATTCAAATGCTCTGGGCCTAACTGTCACAGCCCTCAGCAGCTATGACCCCCAGATGCGAGCC ATAGCCTACCATGTCCTGGCGGCCTACTACTCGCACTTGGAGGGCGCACGGTTCCAAGAGCAGTCCCAGCTACTTTACCTGTTGGATGTA GTCCGGAATGGGATTCGAACTCAGGACATGAGACTTACTTTTACCTTGGCTCTCTTCATTGCCAAAGCAGCCCTGCAGATTTTGAAACCA GAGGAGCACATGTACCTGAAGGTCAGCAACTTCCTGCTGTCGCATGAGTACTTGAACATGGACAAAGTGCCAGGCTTCTACCAGTTCTTC TACAGCTCCGACTTTGAGCAAAAAACAGAGCAGAAGTGGGTGTTTGGCGTTCTGCGGCAGGGGATCCGTGACAAGCAGTGCTACGAACTG TGTGCCCGGCGTGGCATCTTCCACATCATCCTGTCCTTCTTCCACAGCCCGCTGTGTGACGAGGCAGCACAGAATTGGATTCTGGAAATT CTACAGAATGCTGCCCAGGTTGCCAGATCTGCGTATGAAATCATACGAGACTATAGCCTTTTAACATGGATTTTACACATCCTTGAAAGC AAGTTTCTGGAGACTCCGCTGCTGTCTAATGTGATCTCCTTGCTACACACACTGTGGGTGACCAACCTGGGGGACAAGGCAGTGGAGTGG GAGAGCCAGCGCCTTTGCCAGCCTAGCTCCCAGGAGCCTGCCAAGCGGCTTGCCCTGCACCTGGTCAATGAGTTCCTTTATGTTCTCATC GTGCTCATGAAGCACCTGAGGCCCACCTTGGCCCCCGTCCAGCTGACCAACTTCTTCGGGACACTTGACTCCGTGCTGAGGTACCGGGCC ACTGTCATACAGGCCTTTAGGGACATGAACAGATTCACCGTAAATGAGACAGTGCTTTCCACCAAGGACGTCCTTGTCCTCTTGCACAAG TGGAGCCTCATTGAAAGAGACCTCAAGCTCCAGGAAGACCTGAGAGCAGCCATTGAGAAGGCCCAAGCCCGGGAGCTCATGAAAATGCTC AAGGATAAGAACAAGCCTGTCATGCCAGCCCGAGCCAAAGGCCCACGGGGCCGAAAGAGGAGGCCTGGGGAGGCAGAGGAGATGGCTGAC CCTGAGCTGATGGCATCTACCTTGGAGACATGCAAGGGCCTCCTGAGGTCCATCTTGACTTACTGGAGACCAGTGATCCCTGGTCCTGAC CCCACTCAGGAGCCTGTGGACTCAGCCAGCCCCGAGAGCGATGCGCCAGGCCCCGTATATGCTGCCGCTTCCCTGGCAGTCAGTTGGGTG CTGCGGTCGGTGGCCGAGCACCCGCTCAGCAGGGCAGAGGCTGCAGGACTCATTGGCTGGCTTAAGAGCCATATTTTGCCACACCCTGTG GTCGTGGCTGACCTCCTTAAGGACAGTGCCGTGAGGAGCAGCATATTCAGGCTGTATAGCCGGCTCTGTGGGGCTGAGGGGCTGGCAGGG CCTGTGCAGGAGGTGGCCTGCCTGTTCAATACGGTCATGCTGCAGCTGGTGGCTGCCCAGGGCCGGGCAGGGAGCCCCTTCCACCCGGCC ATGGAAGCCCTCTCCCTGTCTTCTCTGAGTGAGAAGGATGAAGCCACACAAGCCTCCGCAGCATTCCTAGTGTCTCTCTACATAAAGGAC ATCTGGCTGGGGGCTCAGCGGCCGGACACCCTCTTAACCCACGTCCGGATGGTGTGTGAGGCCGCAGATGATGCCCCGAGCAGTGAAGAG >In-frame_C21orf59_ENST00000290155_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_6624nt ATGGTTCTGCTGCACGTGAAGCGGGGCGACGAGAGCCAGTTCCTGCTGCAGGCGCCTGGGAGTACCGAGCTGGAGGAGCTCACGGTGCAG GTGGCCCGGGTCTATAATGGGCGGCTCAAGGTGCAGCGCCTCTGCTCAGAAATGGAAGAATTAGCCGAACATGGCATATTTCTCCCTCCT AATATGCAAGGACTGACCGATGATCAGATTGAAGAATTGAAATTGAAGGATGAATGGGGTGAAAAATGCGTACCCAGCGGAGGTGCAGTG TTTAAAAAGGATGATATTGGACGAAGGAATGGGCAAGCTCCAAATGAGAAGATGAAGCAAGTGTTAAAGAAGACTATAGAAGAAGCCAAA GCAATAATATCTAAGGGAGTGTACGACGTTCGGCAGGCCTACGTTCAGTTTGCTCTCTCCTTTTTAATTGCGGGTGATGACAGCACTATA GTGCAGGTGTTGGAAGTGAAAGAATTTATTCCTTGCATTTTTAGCTCAGGGATAAAGGAAGATAGGATCTCTACCATCAATATTTTATTA TCCACACTGAAAACAAAGGTAGTTCACAATAAAAATATCACAAAAACCCAGAAGGTGCGTTTCTTTACGGGGCAGTTATTGAACCACATA GCATCGCTGTACAACTGGAATGGGATTACCGATGTGAACCCAGAAAATGTCAAGGTTTCTGCCGAAGAAGCAGGGAAAACCATGGTGCGG GAGCTTGTTCATAACTTCCTGATGGATCTTTGCTGTTCACTCAAGCATGGAATTAATTTTTACGATGCATCTTTGGGTACCTTTGGCAGA GGCGGAAACCTGACACTCTTGCACTTCTTGCTGGGTTTGAAAACTGCAGCTGATGATGATCTGGTGGCTGACCTTGTGGTAAACATCCTC AAAGTGTGCCCGGACTTACTGAACAAATACTTCAAGGAAGTAACGTTTTCCTTTATCCCACGAGCGAAGTCTACTTGGTTAAATAATATC AAACTACTAAACAAGATCTATGAGGCTCAGCCGGAGATTTCCCGGGCATTTCAGACCAGAGAGTTTATACCCTTGCCTCGGCTCCTGGCA ATGGTGATGGTGACCACCGTGCCCCTGGTGTGCAATAAGAGCATGTTCACCCAAGCATTAAACTTGGACAGCACCTCAGTGAGGCACACA GCCTTATCCCTTATTTCTGTCATTTTGAAGAGGGCATTAAAAACTGTTGACCACTGCCTGAATAAAGAGGTGTGGCAGGAATCAGGCGTG TACACAGCTGTGATGATGGAAGAATTCGTGCAGCTCTTCAGAGAAGCCCTGAGCAAGATTTTGCCAGACCTGAACACTGTCGTGTGGGTC TGGCAGTCACTTAAAAAGCAAGAGACCAAACAGGATGACAAGAAAGGGCAGAAAAGGAGCGATGGGCCCCCGGCTGCCTGCGATGCTCAC CAGTGCGATGATGCAGAAACCATTCTTTTGAAAGCTGTTTTGCTCCAGGTCATATGCCTCTACCAGAAGGTGGTCCCCCACGTGGTCATG CAGTACAACTTTGACTTCAGCAAGCTCCTGAAAGGTGTCATCTCTGAGCAGGGCCTTCGAGAGGAGGTGCCTCCCATTCTGCAGCACCAC ATGCTGAAGGTGGCCCTGGAGCTGCCGGCCAGCAAGTTTCTGTGGTTAAAGGCACAGGAAGGCCCAGATGCAGAAATTATTGGAGGTGAA CGATCAGTATTTTACTTACTAATGAAAATGTTTGTGACCAGTAGCCATTTACAACTGAAGTCATTGACCAAACTTCTGATCATGAAGATT CTGCGGGACACGGGGGTGTTTGAGCACACCTGGAAGGAGCTGGAGCTCTGGCTGGAGCATTTAGAGAACACCATGGAAGAGGACAAAGAG ACTGTGATTCAGTTTCTGGAACGCATTTTATTGACATTGGTGGCGAATCCCTATTCATACACAGACAAAGCATCTGACTTTGTCCAAGAA GCAAGCATGCTGCAGGCCACTATGACGAAGCAAGAAGCCGATGACATGAGCATTCCCATCTCCCACATTGACGATGTTCTCGACATGGTG GATGTCCTGGTGGAGGGCAGTGAAGGCTTGGATGAGGAAATAGGGTTCACGTTGAGTGAAGACATGATCCTGCTCACGTTCCCATTCAGT GCGGTAGTCCCTGCGGCCCTGGAAGCCAGGAATAAGTTGCTCCTTGGGACAGGCAATGAAGCAGCGGAAAACGTTGTGACATATCTGACG GCAGTGCTGACTGACCTCCTCCACACCCAGAGGGACCCCCTGGCTCTGTGTCTCCTGCTCCAGGCATATGATAAGCTTGAGCCTCCATGC CTGGTGCCTTGCTGCCAGCAGCTCTCACGGTTTAACAGATACTACAGCCTCTGGATCCCGGAGCAAGCCCGAGAGGCCTGGCTGCTGCAG GCACAGGGCAGCCCCTCGCCCCCTGCCCTTCCCTTGGCCTCGTCCTTCACAGCCCTGCTGCAGGCAGCCTACGAGAGCCAAGCGCTTCGG GACGAGCACATCCAGGTGCAGCTGCAGGCCACCATGCCACACCTGTCCATGCAGCAGGTCCTGCTCGCGGCCAAGCAGGTGTTGCTCTAC CTGCGGAGCACTGTGGAGAACTTCGGCCAGCTGGGCAGAAGTGTGGGCCCGCCCCTCCTGCAGCTCTTCCTGGATCTCCTCAGGCGCCTG GTTGTCCACTGTGAGCAGCTGGATGCCCAGAACCAGCAGAGATGCGAGGCCGCCCGGGCCGAAGCCGACCTCTTCCTGGACATGGAGTCC GTGGCCTCGCTGGAGTTGGCCAATGATCAGACGCTGGAGGAGGTGCTTGTGGCCATCCTCAGGCACCCCACCCTGGAGGGCTGGTTCCTG GCCCTGGAGCAGCAGGCCCTCCCGCCGCACACGCTCAGCCCTGTCCTCGTGAAGCTCCTGGCCACCCACTTTAGTGCAGGGGTCCTTCAG CTGCTGGCAGCAAGTGCCCCGATCCTCCAGAACATTGGGCAGCTGGGCCTTCTGGCCAGGTACTCAGAGGCCATCACCCAGAGTGTGCTG AAGGAACTTCAGAACAGGAGGGCGGGCCCGGCCACATCACCACCAAAGACCCCGCCGCAGCTGGAGGCCCTGCAGGAGCTGCATCCATAC ATGGAGGGTGCCCAGCTCCGTGAGGTCACCCTGGCCTTGCTGAGCCTGCCTGAGACACACCTGGTGACCCAGCAACCCACGAAATCCCCC GGGAAGGAAAGACACCTGAATGCTCTTGGAAAGACCCTGGTGCAGCTGCTGACCTGCAGCCCCCAGGATCAGCTGCAGAGTGGTGAGCTC CTGTGGTCCTCCGAGTATGTGAGAGGCCTGGGGGCTCTGCTGCCCACGCTAGCAGTGGACGAGCTGGACACAGTGCTCCTCCACACTCTG CAGAGAGACCCTGTGCTGGCCCCCGCAGTCGGGGCTGATCTGCTTGACTACTGCCTGGCCCGGCGCACACAGGCGGCCCTCAGCATCGCT GCCCTGCTCCTCCAGGAGAGCTGCACCCACTTGCTGTGGTTCGAGCAGTGGTGCCTGCAGGCTGGCCCAGGGCTCGGCCTCCAGGGGGAC CTGGACGACTTCCTTCCCCTCATCCATGTGTACCTCCAGTGCAGGACACGGAGCCACTTCACACGCCCAGCAGGAGTGTCTTCCGCTGTC ATTCCTGTCTTGAGGAAGACCCTGTGGAGGCAGCTACAGAGCAGGCTTCTTAGCACTGACAGTCCCCCAGCATCTGGGCTGTACCAGGAG ATCCTGGCACAGCTGGTCCCGTTTGCACGAGCCAAGGATCTCAGTGTACTCATGGACCGCCTGCCCAGCTTGCTTCACACCCCAAGCAGT CACAAGAGGTGGATCGTGGCCGACTCCATTTCAGCAGCTCTGGAAGGGTCAGCAGAAGAGCTGTGTGCCTGGAGAAGGACCCTTTTGGAG TCCTGTGTGAAGTGGCTGATCGTGTCTTTCAGTGGTGGACAGCAAGATGATGATAATACTCAGAATCAGGAGAAGGAAATGCTGCTTAGA TTAAATGCGTTGTTGCATGCACTTAATGAAGTTGATCCTGGTGACTGGCAGAAATTCGTGAAGAAGGGACTCAAATTTCGGTACCAGGAC CACACATTTTTAAAGATGCTCCTCACCGCCGTACAGCTCCTGTACAGCCCAGAAAGCTCCGTGCGCACGAAGCTCATCCAGCTCCCGGTG GTCTACGTGATGCTCATGCAGCACTCGCTGTTTCTGCCGACTCTACTGACGTCTGACGGAGAGGAGAGCCCGGACAGCCAAGTAAAAGAA GCGCTGGTGGACCTGATGCTGACGGTGGTGGAGATGTGCCCCTCTGTCTGTGAGAGCAGCCACTTTGCAGTGCTTCTCGGGGCCTATGGC GCCACTCTCAGCGTCCTAGATCAGAAGATTTTACTTCTGCTTCGAGCGTATGAGCAGAACAAGCTCAGCCTCATCAACTTCAGGGTGCTG CTGTGGGGCCCAGCGGCCGTGGAGCATCACAAGACGTGCCGGAGCCTGGGCAGGTCACTGTGGCAGCAGCCGAGTGTCGGGGACATCCTT CGCCTGCTGGACCGGGACCGGATGATGCAGACCATCCTGCACTTCCCCCAGAACCGGAGGCTGCTGCCCCCCGAGGACACACAGGAGCTG ATATTCAAAGACAAAAGCAGGGTGGATCTTGATGGCCTCTATGACCCCTGCTTTCTCCTTCAGCTCTTCAGTGAGCTGACCAGGCCAGAG TTTGTGGTGGATTGTCGAAAATTTTTGGATTCAAATGCTCTGGGCCTAACTGTCACAGCCCTCAGCAGCTATGACCCCCAGATGCGAGCC ATAGCCTACCATGTCCTGGCGGCCTACTACTCGCACTTGGAGGGCGCACGGTTCCAAGAGCAGTCCCAGCTACTTTACCTGTTGGATGTA GTCCGGAATGGGATTCGAACTCAGGACATGAGACTTACTTTTACCTTGGCTCTCTTCATTGCCAAAGCAGCCCTGCAGATTTTGAAACCA GAGGAGCACATGTACCTGAAGGTCAGCAACTTCCTGCTGTCGCATGAGTACTTGAACATGGACAAAGTGCCAGGCTTCTACCAGTTCTTC TACAGCTCCGACTTTGAGCAAAAAACAGAGCAGAAGTGGGTGTTTGGCGTTCTGCGGCAGGGGATCCGTGACAAGCAGTGCTACGAACTG TGTGCCCGGCGTGGCATCTTCCACATCATCCTGTCCTTCTTCCACAGCCCGCTGTGTGACGAGGCAGCACAGAATTGGATTCTGGAAATT CTACAGAATGCTGCCCAGGTTGCCAGATCTGCGTATGAAATCATACGAGACTATAGCCTTTTAACATGGATTTTACACATCCTTGAAAGC AAGTTTCTGGAGACTCCGCTGCTGTCTAATGTGATCTCCTTGCTACACACACTGTGGGTGACCAACCTGGGGGACAAGGCAGTGGAGTGG GAGAGCCAGCGCCTTTGCCAGCCTAGCTCCCAGGAGCCTGCCAAGCGGCTTGCCCTGCACCTGGTCAATGAGTTCCTTTATGTTCTCATC GTGCTCATGAAGCACCTGAGGCCCACCTTGGCCCCCGTCCAGCTGACCAACTTCTTCGGGACACTTGACTCCGTGCTGAGGTACCGGGCC ACTGTCATACAGGCCTTTAGGGACATGAACAGATTCACCGTAAATGAGACAGTGCTTTCCACCAAGGACGTCCTTGTCCTCTTGCACAAG TGGAGCCTCATTGAAAGAGACCTCAAGCTCCAGGAAGACCTGAGAGCAGCCATTGAGAAGGCCCAAGCCCGGGAGCTCATGAAAATGCTC AAGGATAAGAACAAGCCTGTCATGCCAGCCCGAGCCAAAGGCCCACGGGGCCGAAAGAGGAGGCCTGGGGAGGCAGAGGAGATGGCTGAC CCTGAGCTGATGGCATCTACCTTGGAGACATGCAAGGGCCTCCTGAGGTCCATCTTGACTTACTGGAGACCAGTGATCCCTGGTCCTGAC CCCACTCAGGAGCCTGTGGACTCAGCCAGCCCCGAGAGCGATGCGCCAGGCCCCGTATATGCTGCCGCTTCCCTGGCAGTCAGTTGGGTG CTGCGGTCGGTGGCCGAGCACCCGCTCAGCAGGGCAGAGGCTGCAGGACTCATTGGCTGGCTTAAGAGCCATATTTTGCCACACCCTGTG GTCGTGGCTGACCTCCTTAAGGACAGTGCCGTGAGGAGCAGCATATTCAGGCTGTATAGCCGGCTCTGTGGGGCTGAGGGGCTGGCAGGG CCTGTGCAGGAGGTGGCCTGCCTGTTCAATACGGTCATGCTGCAGCTGGTGGCTGCCCAGGGCCGGGCAGGGAGCCCCTTCCACCCGGCC ATGGAAGCCCTCTCCCTGTCTTCTCTGAGTGAGAAGGATGAAGCCACACAAGCCTCCGCAGCATTCCTAGTGTCTCTCTACATAAAGGAC ATCTGGCTGGGGGCTCAGCGGCCGGACACCCTCTTAACCCACGTCCGGATGGTGTGTGAGGCCGCAGATGATGCCCCGAGCAGTGAAGAG >In-frame_C21orf59_ENST00000540881_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_6456nt ATGGTTCTGCTGCACGTGAAGCGGGGCGACGAGAGCCAGTTCCTGCTGCAGGCGCCTGGGAGTACCGAGCTGGAGGAGCTCACGGTGCAG GTGGCCCGGGTCTATAATGGGCGGCTCAAGGTGCAGCGCCTCTGCTCAGCTCCAAATGAGAAGATGAAGCAAGTGTTAAAGAAGACTATA GAAGAAGCCAAAGCAATAATATCTAAGGGAGTGTACGACGTTCGGCAGGCCTACGTTCAGTTTGCTCTCTCCTTTTTAATTGCGGGTGAT GACAGCACTATAGTGCAGGTGTTGGAAGTGAAAGAATTTATTCCTTGCATTTTTAGCTCAGGGATAAAGGAAGATAGGATCTCTACCATC AATATTTTATTATCCACACTGAAAACAAAGGTAGTTCACAATAAAAATATCACAAAAACCCAGAAGGTGCGTTTCTTTACGGGGCAGTTA TTGAACCACATAGCATCGCTGTACAACTGGAATGGGATTACCGATGTGAACCCAGAAAATGTCAAGGTTTCTGCCGAAGAAGCAGGGAAA ACCATGGTGCGGGAGCTTGTTCATAACTTCCTGATGGATCTTTGCTGTTCACTCAAGCATGGAATTAATTTTTACGATGCATCTTTGGGT ACCTTTGGCAGAGGCGGAAACCTGACACTCTTGCACTTCTTGCTGGGTTTGAAAACTGCAGCTGATGATGATCTGGTGGCTGACCTTGTG GTAAACATCCTCAAAGTGTGCCCGGACTTACTGAACAAATACTTCAAGGAAGTAACGTTTTCCTTTATCCCACGAGCGAAGTCTACTTGG TTAAATAATATCAAACTACTAAACAAGATCTATGAGGCTCAGCCGGAGATTTCCCGGGCATTTCAGACCAGAGAGTTTATACCCTTGCCT CGGCTCCTGGCAATGGTGATGGTGACCACCGTGCCCCTGGTGTGCAATAAGAGCATGTTCACCCAAGCATTAAACTTGGACAGCACCTCA GTGAGGCACACAGCCTTATCCCTTATTTCTGTCATTTTGAAGAGGGCATTAAAAACTGTTGACCACTGCCTGAATAAAGAGGTGTGGCAG GAATCAGGCGTGTACACAGCTGTGATGATGGAAGAATTCGTGCAGCTCTTCAGAGAAGCCCTGAGCAAGATTTTGCCAGACCTGAACACT GTCGTGTGGGTCTGGCAGTCACTTAAAAAGCAAGAGACCAAACAGGATGACAAGAAAGGGCAGAAAAGGAGCGATGGGCCCCCGGCTGCC TGCGATGCTCACCAGTGCGATGATGCAGAAACCATTCTTTTGAAAGCTGTTTTGCTCCAGGTCATATGCCTCTACCAGAAGGTGGTCCCC CACGTGGTCATGCAGTACAACTTTGACTTCAGCAAGCTCCTGAAAGGTGTCATCTCTGAGCAGGGCCTTCGAGAGGAGGTGCCTCCCATT CTGCAGCACCACATGCTGAAGGTGGCCCTGGAGCTGCCGGCCAGCAAGTTTCTGTGGTTAAAGGCACAGGAAGGCCCAGATGCAGAAATT ATTGGAGGTGAACGATCAGTATTTTACTTACTAATGAAAATGTTTGTGACCAGTAGCCATTTACAACTGAAGTCATTGACCAAACTTCTG ATCATGAAGATTCTGCGGGACACGGGGGTGTTTGAGCACACCTGGAAGGAGCTGGAGCTCTGGCTGGAGCATTTAGAGAACACCATGGAA GAGGACAAAGAGACTGTGATTCAGTTTCTGGAACGCATTTTATTGACATTGGTGGCGAATCCCTATTCATACACAGACAAAGCATCTGAC TTTGTCCAAGAAGCAAGCATGCTGCAGGCCACTATGACGAAGCAAGAAGCCGATGACATGAGCATTCCCATCTCCCACATTGACGATGTT CTCGACATGGTGGATGTCCTGGTGGAGGGCAGTGAAGGCTTGGATGAGGAAATAGGGTTCACGTTGAGTGAAGACATGATCCTGCTCACG TTCCCATTCAGTGCGGTAGTCCCTGCGGCCCTGGAAGCCAGGAATAAGTTGCTCCTTGGGACAGGCAATGAAGCAGCGGAAAACGTTGTG ACATATCTGACGGCAGTGCTGACTGACCTCCTCCACACCCAGAGGGACCCCCTGGCTCTGTGTCTCCTGCTCCAGGCATATGATAAGCTT GAGCCTCCATGCCTGGTGCCTTGCTGCCAGCAGCTCTCACGGTTTAACAGATACTACAGCCTCTGGATCCCGGAGCAAGCCCGAGAGGCC TGGCTGCTGCAGGCACAGGGCAGCCCCTCGCCCCCTGCCCTTCCCTTGGCCTCGTCCTTCACAGCCCTGCTGCAGGCAGCCTACGAGAGC CAAGCGCTTCGGGACGAGCACATCCAGGTGCAGCTGCAGGCCACCATGCCACACCTGTCCATGCAGCAGGTCCTGCTCGCGGCCAAGCAG GTGTTGCTCTACCTGCGGAGCACTGTGGAGAACTTCGGCCAGCTGGGCAGAAGTGTGGGCCCGCCCCTCCTGCAGCTCTTCCTGGATCTC CTCAGGCGCCTGGTTGTCCACTGTGAGCAGCTGGATGCCCAGAACCAGCAGAGATGCGAGGCCGCCCGGGCCGAAGCCGACCTCTTCCTG GACATGGAGTCCGTGGCCTCGCTGGAGTTGGCCAATGATCAGACGCTGGAGGAGGTGCTTGTGGCCATCCTCAGGCACCCCACCCTGGAG GGCTGGTTCCTGGCCCTGGAGCAGCAGGCCCTCCCGCCGCACACGCTCAGCCCTGTCCTCGTGAAGCTCCTGGCCACCCACTTTAGTGCA GGGGTCCTTCAGCTGCTGGCAGCAAGTGCCCCGATCCTCCAGAACATTGGGCAGCTGGGCCTTCTGGCCAGGTACTCAGAGGCCATCACC CAGAGTGTGCTGAAGGAACTTCAGAACAGGAGGGCGGGCCCGGCCACATCACCACCAAAGACCCCGCCGCAGCTGGAGGCCCTGCAGGAG CTGCATCCATACATGGAGGGTGCCCAGCTCCGTGAGGTCACCCTGGCCTTGCTGAGCCTGCCTGAGACACACCTGGTGACCCAGCAACCC ACGAAATCCCCCGGGAAGGAAAGACACCTGAATGCTCTTGGAAAGACCCTGGTGCAGCTGCTGACCTGCAGCCCCCAGGATCAGCTGCAG AGTGGTGAGCTCCTGTGGTCCTCCGAGTATGTGAGAGGCCTGGGGGCTCTGCTGCCCACGCTAGCAGTGGACGAGCTGGACACAGTGCTC CTCCACACTCTGCAGAGAGACCCTGTGCTGGCCCCCGCAGTCGGGGCTGATCTGCTTGACTACTGCCTGGCCCGGCGCACACAGGCGGCC CTCAGCATCGCTGCCCTGCTCCTCCAGGAGAGCTGCACCCACTTGCTGTGGTTCGAGCAGTGGTGCCTGCAGGCTGGCCCAGGGCTCGGC CTCCAGGGGGACCTGGACGACTTCCTTCCCCTCATCCATGTGTACCTCCAGTGCAGGACACGGAGCCACTTCACACGCCCAGCAGGAGTG TCTTCCGCTGTCATTCCTGTCTTGAGGAAGACCCTGTGGAGGCAGCTACAGAGCAGGCTTCTTAGCACTGACAGTCCCCCAGCATCTGGG CTGTACCAGGAGATCCTGGCACAGCTGGTCCCGTTTGCACGAGCCAAGGATCTCAGTGTACTCATGGACCGCCTGCCCAGCTTGCTTCAC ACCCCAAGCAGTCACAAGAGGTGGATCGTGGCCGACTCCATTTCAGCAGCTCTGGAAGGGTCAGCAGAAGAGCTGTGTGCCTGGAGAAGG ACCCTTTTGGAGTCCTGTGTGAAGTGGCTGATCGTGTCTTTCAGTGGTGGACAGCAAGATGATGATAATACTCAGAATCAGGAGAAGGAA ATGCTGCTTAGATTAAATGCGTTGTTGCATGCACTTAATGAAGTTGATCCTGGTGACTGGCAGAAATTCGTGAAGAAGGGACTCAAATTT CGGTACCAGGACCACACATTTTTAAAGATGCTCCTCACCGCCGTACAGCTCCTGTACAGCCCAGAAAGCTCCGTGCGCACGAAGCTCATC CAGCTCCCGGTGGTCTACGTGATGCTCATGCAGCACTCGCTGTTTCTGCCGACTCTACTGACGTCTGACGGAGAGGAGAGCCCGGACAGC CAAGTAAAAGAAGCGCTGGTGGACCTGATGCTGACGGTGGTGGAGATGTGCCCCTCTGTCTGTGAGAGCAGCCACTTTGCAGTGCTTCTC GGGGCCTATGGCGCCACTCTCAGCGTCCTAGATCAGAAGATTTTACTTCTGCTTCGAGCGTATGAGCAGAACAAGCTCAGCCTCATCAAC TTCAGGGTGCTGCTGTGGGGCCCAGCGGCCGTGGAGCATCACAAGACGTGCCGGAGCCTGGGCAGGTCACTGTGGCAGCAGCCGAGTGTC GGGGACATCCTTCGCCTGCTGGACCGGGACCGGATGATGCAGACCATCCTGCACTTCCCCCAGAACCGGAGGCTGCTGCCCCCCGAGGAC ACACAGGAGCTGATATTCAAAGACAAAAGCAGGGTGGATCTTGATGGCCTCTATGACCCCTGCTTTCTCCTTCAGCTCTTCAGTGAGCTG ACCAGGCCAGAGTTTGTGGTGGATTGTCGAAAATTTTTGGATTCAAATGCTCTGGGCCTAACTGTCACAGCCCTCAGCAGCTATGACCCC CAGATGCGAGCCATAGCCTACCATGTCCTGGCGGCCTACTACTCGCACTTGGAGGGCGCACGGTTCCAAGAGCAGTCCCAGCTACTTTAC CTGTTGGATGTAGTCCGGAATGGGATTCGAACTCAGGACATGAGACTTACTTTTACCTTGGCTCTCTTCATTGCCAAAGCAGCCCTGCAG ATTTTGAAACCAGAGGAGCACATGTACCTGAAGGTCAGCAACTTCCTGCTGTCGCATGAGTACTTGAACATGGACAAAGTGCCAGGCTTC TACCAGTTCTTCTACAGCTCCGACTTTGAGCAAAAAACAGAGCAGAAGTGGGTGTTTGGCGTTCTGCGGCAGGGGATCCGTGACAAGCAG TGCTACGAACTGTGTGCCCGGCGTGGCATCTTCCACATCATCCTGTCCTTCTTCCACAGCCCGCTGTGTGACGAGGCAGCACAGAATTGG ATTCTGGAAATTCTACAGAATGCTGCCCAGGTTGCCAGATCTGCGTATGAAATCATACGAGACTATAGCCTTTTAACATGGATTTTACAC ATCCTTGAAAGCAAGTTTCTGGAGACTCCGCTGCTGTCTAATGTGATCTCCTTGCTACACACACTGTGGGTGACCAACCTGGGGGACAAG GCAGTGGAGTGGGAGAGCCAGCGCCTTTGCCAGCCTAGCTCCCAGGAGCCTGCCAAGCGGCTTGCCCTGCACCTGGTCAATGAGTTCCTT TATGTTCTCATCGTGCTCATGAAGCACCTGAGGCCCACCTTGGCCCCCGTCCAGCTGACCAACTTCTTCGGGACACTTGACTCCGTGCTG AGGTACCGGGCCACTGTCATACAGGCCTTTAGGGACATGAACAGATTCACCGTAAATGAGACAGTGCTTTCCACCAAGGACGTCCTTGTC CTCTTGCACAAGTGGAGCCTCATTGAAAGAGACCTCAAGCTCCAGGAAGACCTGAGAGCAGCCATTGAGAAGGCCCAAGCCCGGGAGCTC ATGAAAATGCTCAAGGATAAGAACAAGCCTGTCATGCCAGCCCGAGCCAAAGGCCCACGGGGCCGAAAGAGGAGGCCTGGGGAGGCAGAG GAGATGGCTGACCCTGAGCTGATGGCATCTACCTTGGAGACATGCAAGGGCCTCCTGAGGTCCATCTTGACTTACTGGAGACCAGTGATC CCTGGTCCTGACCCCACTCAGGAGCCTGTGGACTCAGCCAGCCCCGAGAGCGATGCGCCAGGCCCCGTATATGCTGCCGCTTCCCTGGCA GTCAGTTGGGTGCTGCGGTCGGTGGCCGAGCACCCGCTCAGCAGGGCAGAGGCTGCAGGACTCATTGGCTGGCTTAAGAGCCATATTTTG CCACACCCTGTGGTCGTGGCTGACCTCCTTAAGGACAGTGCCGTGAGGAGCAGCATATTCAGGCTGTATAGCCGGCTCTGTGGGGCTGAG GGGCTGGCAGGGCCTGTGCAGGAGGTGGCCTGCCTGTTCAATACGGTCATGCTGCAGCTGGTGGCTGCCCAGGGCCGGGCAGGGAGCCCC TTCCACCCGGCCATGGAAGCCCTCTCCCTGTCTTCTCTGAGTGAGAAGGATGAAGCCACACAAGCCTCCGCAGCATTCCTAGTGTCTCTC TACATAAAGGACATCTGGCTGGGGGCTCAGCGGCCGGACACCCTCTTAACCCACGTCCGGATGGTGTGTGAGGCCGCAGATGATGCCCCG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_C21orf59_ENST00000382549_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_10867nt AGAATCAGCTGTCCTCTCAGACTGTGTGGGTGGTTTCCCCGGCCGCAGCTCCGTACGGGCTTGGATTGCTGGGCCTCGGTGCACCCCAGC CTCCCCCACTCGGGTTCTGAGCTTGAGCTGGCGGCTCTTTAACTCTGCTTCACTGTTGCTCTTGGCAACATCCACTTCCGGGAGCGAGTG CCGTTTCCCCCGCTCACCGCGGGCTAGGGAGCGTGGGATTCCGGACTGTGAGCGGCTGTTAGTGCGTCGCAGCTGCTGGCGATCCGGCGA CCCTCGGCCGGCAGGACCCGCGGGCCACGCAGCCGGGGCCTTCTCAACGCCTCAGTACCTCGGCGGGACCGCCATGGTTCTGCTGCACGT GAAGCGGGGCGACGAGAGCCAGTTCCTGCTGCAGGCGCCTGGGAGTACCGAGCTGGAGGAGCTCACGGTGCAGGTGGCCCGGGTCTATAA TGGGCGGCTCAAGGTGCAGCGCCTCTGCTCAGAAATGGAAGAATTAGCCGAACATGGCATATTTCTCCCTCCTAATATGCAAGGACTGAC CGATGATCAGATTGAAGAATTGAAATTGAAGGATGAATGGGGTGAAAAATGCGTACCCAGCGGAGGTGCAGTGTTTAAAAAGGATGATAT TGGACGAAGGAATGGGCAAGCTCCAAATGAGAAGATGAAGCAAGTGTTAAAGAAGACTATAGAAGAAGCCAAAGCAATAATATCTAAGGG AGTGTACGACGTTCGGCAGGCCTACGTTCAGTTTGCTCTCTCCTTTTTAATTGCGGGTGATGACAGCACTATAGTGCAGGTGTTGGAAGT GAAAGAATTTATTCCTTGCATTTTTAGCTCAGGGATAAAGGAAGATAGGATCTCTACCATCAATATTTTATTATCCACACTGAAAACAAA GGTAGTTCACAATAAAAATATCACAAAAACCCAGAAGGTGCGTTTCTTTACGGGGCAGTTATTGAACCACATAGCATCGCTGTACAACTG GAATGGGATTACCGATGTGAACCCAGAAAATGTCAAGGTTTCTGCCGAAGAAGCAGGGAAAACCATGGTGCGGGAGCTTGTTCATAACTT CCTGATGGATCTTTGCTGTTCACTCAAGCATGGAATTAATTTTTACGATGCATCTTTGGGTACCTTTGGCAGAGGCGGAAACCTGACACT CTTGCACTTCTTGCTGGGTTTGAAAACTGCAGCTGATGATGATCTGGTGGCTGACCTTGTGGTAAACATCCTCAAAGTGTGCCCGGACTT ACTGAACAAATACTTCAAGGAAGTAACGTTTTCCTTTATCCCACGAGCGAAGTCTACTTGGTTAAATAATATCAAACTACTAAACAAGAT CTATGAGGCTCAGCCGGAGATTTCCCGGGCATTTCAGACCAGAGAGTTTATACCCTTGCCTCGGCTCCTGGCAATGGTGATGGTGACCAC CGTGCCCCTGGTGTGCAATAAGAGCATGTTCACCCAAGCATTAAACTTGGACAGCACCTCAGTGAGGCACACAGCCTTATCCCTTATTTC TGTCATTTTGAAGAGGGCATTAAAAACTGTTGACCACTGCCTGAATAAAGAGGTGTGGCAGGAATCAGGCGTGTACACAGCTGTGATGAT GGAAGAATTCGTGCAGCTCTTCAGAGAAGCCCTGAGCAAGATTTTGCCAGACCTGAACACTGTCGTGTGGGTCTGGCAGTCACTTAAAAA GCAAGAGACCAAACAGGATGACAAGAAAGGGCAGAAAAGGAGCGATGGGCCCCCGGCTGCCTGCGATGCTCACCAGTGCGATGATGCAGA AACCATTCTTTTGAAAGCTGTTTTGCTCCAGGTCATATGCCTCTACCAGAAGGTGGTCCCCCACGTGGTCATGCAGTACAACTTTGACTT CAGCAAGCTCCTGAAAGGTGTCATCTCTGAGCAGGGCCTTCGAGAGGAGGTGCCTCCCATTCTGCAGCACCACATGCTGAAGGTGGCCCT GGAGCTGCCGGCCAGCAAGTTTCTGTGGTTAAAGGCACAGGAAGGCCCAGATGCAGAAATTATTGGAGGTGAACGATCAGTATTTTACTT ACTAATGAAAATGTTTGTGACCAGTAGCCATTTACAACTGAAGTCATTGACCAAACTTCTGATCATGAAGATTCTGCGGGACACGGGGGT GTTTGAGCACACCTGGAAGGAGCTGGAGCTCTGGCTGGAGCATTTAGAGAACACCATGGAAGAGGACAAAGAGACTGTGATTCAGTTTCT GGAACGCATTTTATTGACATTGGTGGCGAATCCCTATTCATACACAGACAAAGCATCTGACTTTGTCCAAGAAGCAAGCATGCTGCAGGC CACTATGACGAAGCAAGAAGCCGATGACATGAGCATTCCCATCTCCCACATTGACGATGTTCTCGACATGGTGGATGTCCTGGTGGAGGG CAGTGAAGGCTTGGATGAGGAAATAGGGTTCACGTTGAGTGAAGACATGATCCTGCTCACGTTCCCATTCAGTGCGGTAGTCCCTGCGGC CCTGGAAGCCAGGAATAAGTTGCTCCTTGGGACAGGCAATGAAGCAGCGGAAAACGTTGTGACATATCTGACGGCAGTGCTGACTGACCT CCTCCACACCCAGAGGGACCCCCTGGCTCTGTGTCTCCTGCTCCAGGCATATGATAAGCTTGAGCCTCCATGCCTGGTGCCTTGCTGCCA GCAGCTCTCACGGTTTAACAGATACTACAGCCTCTGGATCCCGGAGCAAGCCCGAGAGGCCTGGCTGCTGCAGGCACAGGGCAGCCCCTC GCCCCCTGCCCTTCCCTTGGCCTCGTCCTTCACAGCCCTGCTGCAGGCAGCCTACGAGAGCCAAGCGCTTCGGGACGAGCACATCCAGGT GCAGCTGCAGGCCACCATGCCACACCTGTCCATGCAGCAGGTCCTGCTCGCGGCCAAGCAGGTGTTGCTCTACCTGCGGAGCACTGTGGA GAACTTCGGCCAGCTGGGCAGAAGTGTGGGCCCGCCCCTCCTGCAGCTCTTCCTGGATCTCCTCAGGCGCCTGGTTGTCCACTGTGAGCA GCTGGATGCCCAGAACCAGCAGAGATGCGAGGCCGCCCGGGCCGAAGCCGACCTCTTCCTGGACATGGAGTCCGTGGCCTCGCTGGAGTT GGCCAATGATCAGACGCTGGAGGAGGTGCTTGTGGCCATCCTCAGGCACCCCACCCTGGAGGGCTGGTTCCTGGCCCTGGAGCAGCAGGC CCTCCCGCCGCACACGCTCAGCCCTGTCCTCGTGAAGCTCCTGGCCACCCACTTTAGTGCAGGGGTCCTTCAGCTGCTGGCAGCAAGTGC CCCGATCCTCCAGAACATTGGGCAGCTGGGCCTTCTGGCCAGGTACTCAGAGGCCATCACCCAGAGTGTGCTGAAGGAACTTCAGAACAG GAGGGCGGGCCCGGCCACATCACCACCAAAGACCCCGCCGCAGCTGGAGGCCCTGCAGGAGCTGCATCCATACATGGAGGGTGCCCAGCT CCGTGAGGTCACCCTGGCCTTGCTGAGCCTGCCTGAGACACACCTGGTGACCCAGCAACCCACGAAATCCCCCGGGAAGGAAAGACACCT GAATGCTCTTGGAAAGACCCTGGTGCAGCTGCTGACCTGCAGCCCCCAGGATCAGCTGCAGAGTGGTGAGCTCCTGTGGTCCTCCGAGTA TGTGAGAGGCCTGGGGGCTCTGCTGCCCACGCTAGCAGTGGACGAGCTGGACACAGTGCTCCTCCACACTCTGCAGAGAGACCCTGTGCT GGCCCCCGCAGTCGGGGCTGATCTGCTTGACTACTGCCTGGCCCGGCGCACACAGGCGGCCCTCAGCATCGCTGCCCTGCTCCTCCAGGA GAGCTGCACCCACTTGCTGTGGTTCGAGCAGTGGTGCCTGCAGGCTGGCCCAGGGCTCGGCCTCCAGGGGGACCTGGACGACTTCCTTCC CCTCATCCATGTGTACCTCCAGTGCAGGACACGGAGCCACTTCACACGCCCAGCAGGAGTGTCTTCCGCTGTCATTCCTGTCTTGAGGAA GACCCTGTGGAGGCAGCTACAGAGCAGGCTTCTTAGCACTGACAGTCCCCCAGCATCTGGGCTGTACCAGGAGATCCTGGCACAGCTGGT CCCGTTTGCACGAGCCAAGGATCTCAGTGTACTCATGGACCGCCTGCCCAGCTTGCTTCACACCCCAAGCAGTCACAAGAGGTGGATCGT GGCCGACTCCATTTCAGCAGCTCTGGAAGGGTCAGCAGAAGAGCTGTGTGCCTGGAGAAGGACCCTTTTGGAGTCCTGTGTGAAGTGGCT GATCGTGTCTTTCAGTGGTGGACAGCAAGATGATGATAATACTCAGAATCAGGAGAAGGAAATGCTGCTTAGATTAAATGCGTTGTTGCA TGCACTTAATGAAGTTGATCCTGGTGACTGGCAGAAATTCGTGAAGAAGGGACTCAAATTTCGGTACCAGGACCACACATTTTTAAAGAT GCTCCTCACCGCCGTACAGCTCCTGTACAGCCCAGAAAGCTCCGTGCGCACGAAGCTCATCCAGCTCCCGGTGGTCTACGTGATGCTCAT GCAGCACTCGCTGTTTCTGCCGACTCTACTGACGTCTGACGGAGAGGAGAGCCCGGACAGCCAAGTAAAAGAAGCGCTGGTGGACCTGAT GCTGACGGTGGTGGAGATGTGCCCCTCTGTCTGTGAGAGCAGCCACTTTGCAGTGCTTCTCGGGGCCTATGGCGCCACTCTCAGCGTCCT AGATCAGAAGATTTTACTTCTGCTTCGAGCGTATGAGCAGAACAAGCTCAGCCTCATCAACTTCAGGGTGCTGCTGTGGGGCCCAGCGGC CGTGGAGCATCACAAGACGTGCCGGAGCCTGGGCAGGTCACTGTGGCAGCAGCCGAGTGTCGGGGACATCCTTCGCCTGCTGGACCGGGA CCGGATGATGCAGACCATCCTGCACTTCCCCCAGAACCGGAGGCTGCTGCCCCCCGAGGACACACAGGAGCTGATATTCAAAGACAAAAG CAGGGTGGATCTTGATGGCCTCTATGACCCCTGCTTTCTCCTTCAGCTCTTCAGTGAGCTGACCAGGCCAGAGTTTGTGGTGGATTGTCG AAAATTTTTGGATTCAAATGCTCTGGGCCTAACTGTCACAGCCCTCAGCAGCTATGACCCCCAGATGCGAGCCATAGCCTACCATGTCCT GGCGGCCTACTACTCGCACTTGGAGGGCGCACGGTTCCAAGAGCAGTCCCAGCTACTTTACCTGTTGGATGTAGTCCGGAATGGGATTCG AACTCAGGACATGAGACTTACTTTTACCTTGGCTCTCTTCATTGCCAAAGCAGCCCTGCAGATTTTGAAACCAGAGGAGCACATGTACCT GAAGGTCAGCAACTTCCTGCTGTCGCATGAGTACTTGAACATGGACAAAGTGCCAGGCTTCTACCAGTTCTTCTACAGCTCCGACTTTGA GCAAAAAACAGAGCAGAAGTGGGTGTTTGGCGTTCTGCGGCAGGGGATCCGTGACAAGCAGTGCTACGAACTGTGTGCCCGGCGTGGCAT CTTCCACATCATCCTGTCCTTCTTCCACAGCCCGCTGTGTGACGAGGCAGCACAGAATTGGATTCTGGAAATTCTACAGAATGCTGCCCA GGTTGCCAGATCTGCGTATGAAATCATACGAGACTATAGCCTTTTAACATGGATTTTACACATCCTTGAAAGCAAGTTTCTGGAGACTCC GCTGCTGTCTAATGTGATCTCCTTGCTACACACACTGTGGGTGACCAACCTGGGGGACAAGGCAGTGGAGTGGGAGAGCCAGCGCCTTTG CCAGCCTAGCTCCCAGGAGCCTGCCAAGCGGCTTGCCCTGCACCTGGTCAATGAGTTCCTTTATGTTCTCATCGTGCTCATGAAGCACCT GAGGCCCACCTTGGCCCCCGTCCAGCTGACCAACTTCTTCGGGACACTTGACTCCGTGCTGAGGTACCGGGCCACTGTCATACAGGCCTT TAGGGACATGAACAGATTCACCGTAAATGAGACAGTGCTTTCCACCAAGGACGTCCTTGTCCTCTTGCACAAGTGGAGCCTCATTGAAAG AGACCTCAAGCTCCAGGAAGACCTGAGAGCAGCCATTGAGAAGGCCCAAGCCCGGGAGCTCATGAAAATGCTCAAGGATAAGAACAAGCC TGTCATGCCAGCCCGAGCCAAAGGCCCACGGGGCCGAAAGAGGAGGCCTGGGGAGGCAGAGGAGATGGCTGACCCTGAGCTGATGGCATC TACCTTGGAGACATGCAAGGGCCTCCTGAGGTCCATCTTGACTTACTGGAGACCAGTGATCCCTGGTCCTGACCCCACTCAGGAGCCTGT GGACTCAGCCAGCCCCGAGAGCGATGCGCCAGGCCCCGTATATGCTGCCGCTTCCCTGGCAGTCAGTTGGGTGCTGCGGTCGGTGGCCGA GCACCCGCTCAGCAGGGCAGAGGCTGCAGGACTCATTGGCTGGCTTAAGAGCCATATTTTGCCACACCCTGTGGTCGTGGCTGACCTCCT TAAGGACAGTGCCGTGAGGAGCAGCATATTCAGGCTGTATAGCCGGCTCTGTGGGGCTGAGGGGCTGGCAGGGCCTGTGCAGGAGGTGGC CTGCCTGTTCAATACGGTCATGCTGCAGCTGGTGGCTGCCCAGGGCCGGGCAGGGAGCCCCTTCCACCCGGCCATGGAAGCCCTCTCCCT GTCTTCTCTGAGTGAGAAGGATGAAGCCACACAAGCCTCCGCAGCATTCCTAGTGTCTCTCTACATAAAGGACATCTGGCTGGGGGCTCA GCGGCCGGACACCCTCTTAACCCACGTCCGGATGGTGTGTGAGGCCGCAGATGATGCCCCGAGCAGTGAAGAGGAGGCCATCGTGGTGCT CTGCAAGGACGCCGCCAGCGCAGCCTCAGATGCTTGACTCCTGCCGGCCAGCACCTTGCACCCTGATGACCAGAGCCTCGAGCACAGCAC CAGCTTCTAGAAGTTTGGTTGAGTCAAGGGTTTCCAGAGAAGGCATGGGAAACAACAGGTTCAGTACATTGGCTCAGTTCTTTGACAAGA AAAGTTGAGAGGACTTTATTGAACTGCCCAGTAAATGATAAACTCGGGCCTGTAGGTGCCCAGCATCAGAGTTGCAAGGAATGTGGGGAC TTCTAGGCCATGAGGCCCATCCAGTGCCTCGTCAGGCCGCCCCTTCCTCTCTAGGGGCTTGGAGCTCATCACAGGAAATAGCTCGAGTTT GAGGCAGCACTTCTGAATGCAGAAGAGATTCATCTGTGTTAAAGCTGAAATGTCAAAAGGTATCAGATTTTTTTTATGAAAACGAAGAGA GATGTTTAAAGTTTATTTTTCAGCAGGTGAGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGAATCACCTGAGG TCAGGAGTTCGAAACCAGCCTTCCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTAGCGCACACCTG TAATTCCAGCTACTCGGGAGGCTAAGGCAGGGGAATCGCTTGAACCTGGGAGGTGGAGGCTACAGTGAGCTGAGATCGTGCCATTGCGCT CCAGCCTAGGTGACAGAGCAAGACTCCATCTCAAAAAAATAAAAAAATAAAGTTTGTTTTTCTATAAAAAGTCATAACAAAGTATTAGTA TGACTTTTTGAATAAGTTAATTTCTGCCAGTGTTTAATTATTTTATTAAAGAAAAGGATGTTACACTGAATCCTTAAAGAATAAAAGTGA TTTGACCTCTGCTTTGAGAAGACAGCCTGTAATTTTTAAAGCTATACTTCAAAGAGGGGATTTTGAATTTTATAAATGCTTGTTAATGTC TATTTTTGTAAGGTTTTTGTGTTTTCCTTTCATTGTTGTCAAGAGGCTATTTTTGCTCCACATAGGCCTGCATTTATTTTAAAGGTCAGA ATTTTACTCTTAATGGTCATATATTAGTTGGGGTTGTAGCTGACAAAAGTCATGAAATTTCGTGGTTTTCACAGTTAAAATTTCCGTCTG TTCCTTTAAAACTCTCCTGCATGCCTGGGGCTCTTGGGATCTGCTCTGTGGCCTAGGATGTGGCTGTTTTATCTGCCGTATAATGTACAT CGTGCTGACAATGCCTTGGTTTTGTCTGAAACATTTACACTTCTATTTTCCACCAGTGTTCTTTAGAATTGTTTCTGTTTTAGGTGACTT AAAGTTTTAACTAAAGCATGAGTAACGTTTGTTGGCATACAGTCCCTTCACCACAAATAATTGTCTTGCACTGTCTACAAAGCAAGGATC AGTTACCTCACTTGTCCCCTTCCCTACCCAAATAAACCTTACAACGCTATTCTTTGAGACTATCCTGAACTTGAAATCCCACGTTTAGAT CCAAGCTGGACTCAGGCAAGCGCTGCTCCAACAAAGCGTTCTCTTCCTGGTTCCCCTTAATCTTTATCCACCTCTCCAAGGCCTATCTTT GGGGATTCCTTTGGTTATAGGCACCTCTGCTTGTTTATGCAGGGGGCATTGGCCGGAAGGACATTGGTCTGGGGAATATCCCTGAACCCC ATGCCTCTGGGGGCACAGGGAGGGGCAGCGAGCAGGTGGGGTGGATTTCCACGGCTTCATCCCTGGCTCCAGGCCTAAGCTGCCTCCCAG GTTCTTAGGGCCCAGCAAGTCAATACATACTACGTCAGGTGGCGACAAATGCTCCAAAGCCGAGTTCCAGCTCAGTCAAGTGAGGACACA TTTTCAGCACCTCACCTTCTTTTCTGCATCTCTGGAGCTCATCAGTCTTGCTTTTCTTTGTTCTCCCTTTTAAATCCACTGCCCTGACCT TGTTCGTGTATTTTCCAGTCACTTAGTGTGGAGGAAGGGAATCTCATCCCATGGAGAATAGATCGAACATGGTCTTCACCTGACTTAAAA TATAAAATGCTAAATTAGAAATATCTTAAGTGGGGCGGGGGGCACAGTTATTTTAAAAATAAAACCTATCAACTCCCTCCTTGCCTGAAA GCTGTAGGGGACATATGGGTCTTCTGAGATTTGCTGTGTGATGCTGTCTCCTCTCCAGGGACAAGGCTGCTGGGCACTAGAGGACTAGAT CTTTCAAGGGTCCCAGATCCACTGTCACATAAAGTCACATCCAGAAGACCTTTCCTGCCAGCTTCCAGGGCTCTTTGTGTTCTGTGACAG CATTTGGGCATAGATCCTGCTTACCCGGCCTGGCTGCTGACAGGCGTTGGCTGCCTGCCCTCCAGGGGAGACACTTTCTTGGGCTCTGTC TTTGAAAGGCTGTGGGGAGGTTGAAGGTGCAACTCAGGTCCCCAGACTGCAGTGAGCTGACCTGGCAGGGCAGATGCCATCACATCTGGG GGAGCCGGCGGGTGTTAGTGGAGCTTGGATGGGAACTTACCCAGCATCCTAACAAAGGTACAGAAGGACCAGGTGAACTCAGGGCTGATA ACGCATTACACAGTAATGGTAAAGTGGCATAGTAAAGATTAGTAAGCAAACAGCTTTTCCTCTTGATTTGCATATATTTTATTTTCCTAC TCTTCCCTGAGCAAATATAAGCAGTAAGCAAGCAGGCTAGGTGTGCTCAATAAACTCAGCAACACCTGGGATGACCTCTGCACTCGAGGG GCCACTGCAATCTTTGTCAAAGGCATAGGATGCTCCTGCTCTAGTTGCACTTGACCTAGGTGCCCTTTCTGCTACATGCAAATGGCCTCT AAGAAGAACGAGGAACGTATGTGTCCAGGTTGGCTTGATTTCACCAGTTCACTCAGCTATGGCCACGATTTACTGACATCAGCTCTGCAA TTGAGAGGTCCTGTCTCCAGGGGGAGGCTCGCTGGGCTTGCTCCTGACGAGGGGACCCCCATTGAGGGTCAGTTCCCAGAGGAGAGTGGG GTGGGTCTGGAAACCCCCGAGGGGCAAGGTGGAGGAGCTCTCCTGTCGTAGCGGCTGGTCAGGGCCAGTTCTGCTCCCTGGCTCCACTGA GCTCGCCTGAGCCTGTGAGGTTGCCAGGGGTTCCCTGTGGCACGGCAGGCACTTCTGGATGCAGAGGTGGAGGTTGAGGCCGTGACTCCA GGGGCATGTTTGGTGGTGCTTGGGGCTGTTCCTGTGAACAGAGCAGAGTGGGAGGCAGGCATCATAGTTGCTGCAGAACAGTCCATACTG TGGGGCTGGGGGGTTTCCTGCCACACCTGCCATCTGCCCGGACCCCATAGGGAAGGCCACACAGGCAAATTCCTGAGAAGGGTCAGCCAG CTCACAAAGGTGGCCATTCTAGAGAAATCTCAGAGGAGAGGAAGTGCTTTGTCAGGAACTAGGCCTCAGGTCTTTCCCTGGAGGCCACTT CTTCCTACATTGATTTAGGATGGGGGGGGTGGGGGGTGGAGGGGAGCAGGTTGACCTCCCATCCAGCGCTGTATCTGAGTGTAGTTCATT TTATATCCATAGCCCAAGCCAACTTGTATCTTGGTGATATGGTTTGGCTGCGTCACGACACAAATCTCACCTTGAATTGTAATAATCCCC ACGTGTCGTGGGAAGGACCCAGTGGGAGGTAATTGAATCATGGGGGCGGGTCTTCCCATGCTGTTCTCGTGATAGTAAGTCTCATGAGAT CTGATGGTTTTATAAAGGGGAGTTTCCCTGCACATGCCCTTTTGCCTGTGTCATGTAAGATGTGGCTTTGCTCTTCCTTTGCCTTCTGCC >In-frame_C21orf59_ENST00000290155_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_11147nt TGGAGACTGAAAGCGGCGGAAGGGACGCTGGAATGTGGAGCGGTTGTGGGGCGGCAGCTGCGGAACTGCGCGATTGTGGTTCCCGCCGTA TTTCCCGTTCCCCATCTAGTAACTCCCATCTCAGCCCACGTATCTCCCTGAGTGGAAATCTCGGGCCCCAGACCAGTCGATTGGGAGGTC CGCCCTCCCCTTCAGCGACTTGGTCTGTGTTTTGGCAGTTGCCGCGACAACAGTCACTTCCGGGAAGGGGCTCTGCGAATCTCCTTCCGT CGGTCCGCTCAGAATCAGCTGTCCTCTCAGACTGTGTGGGTGGTTTCCCCGGCCGCAGCTCCGTACGGGCTTGGATTGCTGGGCCTCGGT GCACCCCAGCCTCCCCCACTCGGGTTCTGAGCTTGAGCTGGCGGCTCTTTAACTCTGCTTCACTGTTGCTCTTGGCAACATCCACTTCCG GGAGCGAGTGCCGTTTCCCCCGCTCACCGCGGGCTAGGGAGCGTGGGATTCCGGACTGTGAGCGGCTGTTAGTGCGTCGCAGCTGCTGGC GATCCGGCGACCCTCGGCCGGCAGGACCCGCGGGCCACGCAGCCGGGGCCTTCTCAACGCCTCAGTACCTCGGCGGGACCGCCATGGTTC TGCTGCACGTGAAGCGGGGCGACGAGAGCCAGTTCCTGCTGCAGGCGCCTGGGAGTACCGAGCTGGAGGAGCTCACGGTGCAGGTGGCCC GGGTCTATAATGGGCGGCTCAAGGTGCAGCGCCTCTGCTCAGAAATGGAAGAATTAGCCGAACATGGCATATTTCTCCCTCCTAATATGC AAGGACTGACCGATGATCAGATTGAAGAATTGAAATTGAAGGATGAATGGGGTGAAAAATGCGTACCCAGCGGAGGTGCAGTGTTTAAAA AGGATGATATTGGACGAAGGAATGGGCAAGCTCCAAATGAGAAGATGAAGCAAGTGTTAAAGAAGACTATAGAAGAAGCCAAAGCAATAA TATCTAAGGGAGTGTACGACGTTCGGCAGGCCTACGTTCAGTTTGCTCTCTCCTTTTTAATTGCGGGTGATGACAGCACTATAGTGCAGG TGTTGGAAGTGAAAGAATTTATTCCTTGCATTTTTAGCTCAGGGATAAAGGAAGATAGGATCTCTACCATCAATATTTTATTATCCACAC TGAAAACAAAGGTAGTTCACAATAAAAATATCACAAAAACCCAGAAGGTGCGTTTCTTTACGGGGCAGTTATTGAACCACATAGCATCGC TGTACAACTGGAATGGGATTACCGATGTGAACCCAGAAAATGTCAAGGTTTCTGCCGAAGAAGCAGGGAAAACCATGGTGCGGGAGCTTG TTCATAACTTCCTGATGGATCTTTGCTGTTCACTCAAGCATGGAATTAATTTTTACGATGCATCTTTGGGTACCTTTGGCAGAGGCGGAA ACCTGACACTCTTGCACTTCTTGCTGGGTTTGAAAACTGCAGCTGATGATGATCTGGTGGCTGACCTTGTGGTAAACATCCTCAAAGTGT GCCCGGACTTACTGAACAAATACTTCAAGGAAGTAACGTTTTCCTTTATCCCACGAGCGAAGTCTACTTGGTTAAATAATATCAAACTAC TAAACAAGATCTATGAGGCTCAGCCGGAGATTTCCCGGGCATTTCAGACCAGAGAGTTTATACCCTTGCCTCGGCTCCTGGCAATGGTGA TGGTGACCACCGTGCCCCTGGTGTGCAATAAGAGCATGTTCACCCAAGCATTAAACTTGGACAGCACCTCAGTGAGGCACACAGCCTTAT CCCTTATTTCTGTCATTTTGAAGAGGGCATTAAAAACTGTTGACCACTGCCTGAATAAAGAGGTGTGGCAGGAATCAGGCGTGTACACAG CTGTGATGATGGAAGAATTCGTGCAGCTCTTCAGAGAAGCCCTGAGCAAGATTTTGCCAGACCTGAACACTGTCGTGTGGGTCTGGCAGT CACTTAAAAAGCAAGAGACCAAACAGGATGACAAGAAAGGGCAGAAAAGGAGCGATGGGCCCCCGGCTGCCTGCGATGCTCACCAGTGCG ATGATGCAGAAACCATTCTTTTGAAAGCTGTTTTGCTCCAGGTCATATGCCTCTACCAGAAGGTGGTCCCCCACGTGGTCATGCAGTACA ACTTTGACTTCAGCAAGCTCCTGAAAGGTGTCATCTCTGAGCAGGGCCTTCGAGAGGAGGTGCCTCCCATTCTGCAGCACCACATGCTGA AGGTGGCCCTGGAGCTGCCGGCCAGCAAGTTTCTGTGGTTAAAGGCACAGGAAGGCCCAGATGCAGAAATTATTGGAGGTGAACGATCAG TATTTTACTTACTAATGAAAATGTTTGTGACCAGTAGCCATTTACAACTGAAGTCATTGACCAAACTTCTGATCATGAAGATTCTGCGGG ACACGGGGGTGTTTGAGCACACCTGGAAGGAGCTGGAGCTCTGGCTGGAGCATTTAGAGAACACCATGGAAGAGGACAAAGAGACTGTGA TTCAGTTTCTGGAACGCATTTTATTGACATTGGTGGCGAATCCCTATTCATACACAGACAAAGCATCTGACTTTGTCCAAGAAGCAAGCA TGCTGCAGGCCACTATGACGAAGCAAGAAGCCGATGACATGAGCATTCCCATCTCCCACATTGACGATGTTCTCGACATGGTGGATGTCC TGGTGGAGGGCAGTGAAGGCTTGGATGAGGAAATAGGGTTCACGTTGAGTGAAGACATGATCCTGCTCACGTTCCCATTCAGTGCGGTAG TCCCTGCGGCCCTGGAAGCCAGGAATAAGTTGCTCCTTGGGACAGGCAATGAAGCAGCGGAAAACGTTGTGACATATCTGACGGCAGTGC TGACTGACCTCCTCCACACCCAGAGGGACCCCCTGGCTCTGTGTCTCCTGCTCCAGGCATATGATAAGCTTGAGCCTCCATGCCTGGTGC CTTGCTGCCAGCAGCTCTCACGGTTTAACAGATACTACAGCCTCTGGATCCCGGAGCAAGCCCGAGAGGCCTGGCTGCTGCAGGCACAGG GCAGCCCCTCGCCCCCTGCCCTTCCCTTGGCCTCGTCCTTCACAGCCCTGCTGCAGGCAGCCTACGAGAGCCAAGCGCTTCGGGACGAGC ACATCCAGGTGCAGCTGCAGGCCACCATGCCACACCTGTCCATGCAGCAGGTCCTGCTCGCGGCCAAGCAGGTGTTGCTCTACCTGCGGA GCACTGTGGAGAACTTCGGCCAGCTGGGCAGAAGTGTGGGCCCGCCCCTCCTGCAGCTCTTCCTGGATCTCCTCAGGCGCCTGGTTGTCC ACTGTGAGCAGCTGGATGCCCAGAACCAGCAGAGATGCGAGGCCGCCCGGGCCGAAGCCGACCTCTTCCTGGACATGGAGTCCGTGGCCT CGCTGGAGTTGGCCAATGATCAGACGCTGGAGGAGGTGCTTGTGGCCATCCTCAGGCACCCCACCCTGGAGGGCTGGTTCCTGGCCCTGG AGCAGCAGGCCCTCCCGCCGCACACGCTCAGCCCTGTCCTCGTGAAGCTCCTGGCCACCCACTTTAGTGCAGGGGTCCTTCAGCTGCTGG CAGCAAGTGCCCCGATCCTCCAGAACATTGGGCAGCTGGGCCTTCTGGCCAGGTACTCAGAGGCCATCACCCAGAGTGTGCTGAAGGAAC TTCAGAACAGGAGGGCGGGCCCGGCCACATCACCACCAAAGACCCCGCCGCAGCTGGAGGCCCTGCAGGAGCTGCATCCATACATGGAGG GTGCCCAGCTCCGTGAGGTCACCCTGGCCTTGCTGAGCCTGCCTGAGACACACCTGGTGACCCAGCAACCCACGAAATCCCCCGGGAAGG AAAGACACCTGAATGCTCTTGGAAAGACCCTGGTGCAGCTGCTGACCTGCAGCCCCCAGGATCAGCTGCAGAGTGGTGAGCTCCTGTGGT CCTCCGAGTATGTGAGAGGCCTGGGGGCTCTGCTGCCCACGCTAGCAGTGGACGAGCTGGACACAGTGCTCCTCCACACTCTGCAGAGAG ACCCTGTGCTGGCCCCCGCAGTCGGGGCTGATCTGCTTGACTACTGCCTGGCCCGGCGCACACAGGCGGCCCTCAGCATCGCTGCCCTGC TCCTCCAGGAGAGCTGCACCCACTTGCTGTGGTTCGAGCAGTGGTGCCTGCAGGCTGGCCCAGGGCTCGGCCTCCAGGGGGACCTGGACG ACTTCCTTCCCCTCATCCATGTGTACCTCCAGTGCAGGACACGGAGCCACTTCACACGCCCAGCAGGAGTGTCTTCCGCTGTCATTCCTG TCTTGAGGAAGACCCTGTGGAGGCAGCTACAGAGCAGGCTTCTTAGCACTGACAGTCCCCCAGCATCTGGGCTGTACCAGGAGATCCTGG CACAGCTGGTCCCGTTTGCACGAGCCAAGGATCTCAGTGTACTCATGGACCGCCTGCCCAGCTTGCTTCACACCCCAAGCAGTCACAAGA GGTGGATCGTGGCCGACTCCATTTCAGCAGCTCTGGAAGGGTCAGCAGAAGAGCTGTGTGCCTGGAGAAGGACCCTTTTGGAGTCCTGTG TGAAGTGGCTGATCGTGTCTTTCAGTGGTGGACAGCAAGATGATGATAATACTCAGAATCAGGAGAAGGAAATGCTGCTTAGATTAAATG CGTTGTTGCATGCACTTAATGAAGTTGATCCTGGTGACTGGCAGAAATTCGTGAAGAAGGGACTCAAATTTCGGTACCAGGACCACACAT TTTTAAAGATGCTCCTCACCGCCGTACAGCTCCTGTACAGCCCAGAAAGCTCCGTGCGCACGAAGCTCATCCAGCTCCCGGTGGTCTACG TGATGCTCATGCAGCACTCGCTGTTTCTGCCGACTCTACTGACGTCTGACGGAGAGGAGAGCCCGGACAGCCAAGTAAAAGAAGCGCTGG TGGACCTGATGCTGACGGTGGTGGAGATGTGCCCCTCTGTCTGTGAGAGCAGCCACTTTGCAGTGCTTCTCGGGGCCTATGGCGCCACTC TCAGCGTCCTAGATCAGAAGATTTTACTTCTGCTTCGAGCGTATGAGCAGAACAAGCTCAGCCTCATCAACTTCAGGGTGCTGCTGTGGG GCCCAGCGGCCGTGGAGCATCACAAGACGTGCCGGAGCCTGGGCAGGTCACTGTGGCAGCAGCCGAGTGTCGGGGACATCCTTCGCCTGC TGGACCGGGACCGGATGATGCAGACCATCCTGCACTTCCCCCAGAACCGGAGGCTGCTGCCCCCCGAGGACACACAGGAGCTGATATTCA AAGACAAAAGCAGGGTGGATCTTGATGGCCTCTATGACCCCTGCTTTCTCCTTCAGCTCTTCAGTGAGCTGACCAGGCCAGAGTTTGTGG TGGATTGTCGAAAATTTTTGGATTCAAATGCTCTGGGCCTAACTGTCACAGCCCTCAGCAGCTATGACCCCCAGATGCGAGCCATAGCCT ACCATGTCCTGGCGGCCTACTACTCGCACTTGGAGGGCGCACGGTTCCAAGAGCAGTCCCAGCTACTTTACCTGTTGGATGTAGTCCGGA ATGGGATTCGAACTCAGGACATGAGACTTACTTTTACCTTGGCTCTCTTCATTGCCAAAGCAGCCCTGCAGATTTTGAAACCAGAGGAGC ACATGTACCTGAAGGTCAGCAACTTCCTGCTGTCGCATGAGTACTTGAACATGGACAAAGTGCCAGGCTTCTACCAGTTCTTCTACAGCT CCGACTTTGAGCAAAAAACAGAGCAGAAGTGGGTGTTTGGCGTTCTGCGGCAGGGGATCCGTGACAAGCAGTGCTACGAACTGTGTGCCC GGCGTGGCATCTTCCACATCATCCTGTCCTTCTTCCACAGCCCGCTGTGTGACGAGGCAGCACAGAATTGGATTCTGGAAATTCTACAGA ATGCTGCCCAGGTTGCCAGATCTGCGTATGAAATCATACGAGACTATAGCCTTTTAACATGGATTTTACACATCCTTGAAAGCAAGTTTC TGGAGACTCCGCTGCTGTCTAATGTGATCTCCTTGCTACACACACTGTGGGTGACCAACCTGGGGGACAAGGCAGTGGAGTGGGAGAGCC AGCGCCTTTGCCAGCCTAGCTCCCAGGAGCCTGCCAAGCGGCTTGCCCTGCACCTGGTCAATGAGTTCCTTTATGTTCTCATCGTGCTCA TGAAGCACCTGAGGCCCACCTTGGCCCCCGTCCAGCTGACCAACTTCTTCGGGACACTTGACTCCGTGCTGAGGTACCGGGCCACTGTCA TACAGGCCTTTAGGGACATGAACAGATTCACCGTAAATGAGACAGTGCTTTCCACCAAGGACGTCCTTGTCCTCTTGCACAAGTGGAGCC TCATTGAAAGAGACCTCAAGCTCCAGGAAGACCTGAGAGCAGCCATTGAGAAGGCCCAAGCCCGGGAGCTCATGAAAATGCTCAAGGATA AGAACAAGCCTGTCATGCCAGCCCGAGCCAAAGGCCCACGGGGCCGAAAGAGGAGGCCTGGGGAGGCAGAGGAGATGGCTGACCCTGAGC TGATGGCATCTACCTTGGAGACATGCAAGGGCCTCCTGAGGTCCATCTTGACTTACTGGAGACCAGTGATCCCTGGTCCTGACCCCACTC AGGAGCCTGTGGACTCAGCCAGCCCCGAGAGCGATGCGCCAGGCCCCGTATATGCTGCCGCTTCCCTGGCAGTCAGTTGGGTGCTGCGGT CGGTGGCCGAGCACCCGCTCAGCAGGGCAGAGGCTGCAGGACTCATTGGCTGGCTTAAGAGCCATATTTTGCCACACCCTGTGGTCGTGG CTGACCTCCTTAAGGACAGTGCCGTGAGGAGCAGCATATTCAGGCTGTATAGCCGGCTCTGTGGGGCTGAGGGGCTGGCAGGGCCTGTGC AGGAGGTGGCCTGCCTGTTCAATACGGTCATGCTGCAGCTGGTGGCTGCCCAGGGCCGGGCAGGGAGCCCCTTCCACCCGGCCATGGAAG CCCTCTCCCTGTCTTCTCTGAGTGAGAAGGATGAAGCCACACAAGCCTCCGCAGCATTCCTAGTGTCTCTCTACATAAAGGACATCTGGC TGGGGGCTCAGCGGCCGGACACCCTCTTAACCCACGTCCGGATGGTGTGTGAGGCCGCAGATGATGCCCCGAGCAGTGAAGAGGAGGCCA TCGTGGTGCTCTGCAAGGACGCCGCCAGCGCAGCCTCAGATGCTTGACTCCTGCCGGCCAGCACCTTGCACCCTGATGACCAGAGCCTCG AGCACAGCACCAGCTTCTAGAAGTTTGGTTGAGTCAAGGGTTTCCAGAGAAGGCATGGGAAACAACAGGTTCAGTACATTGGCTCAGTTC TTTGACAAGAAAAGTTGAGAGGACTTTATTGAACTGCCCAGTAAATGATAAACTCGGGCCTGTAGGTGCCCAGCATCAGAGTTGCAAGGA ATGTGGGGACTTCTAGGCCATGAGGCCCATCCAGTGCCTCGTCAGGCCGCCCCTTCCTCTCTAGGGGCTTGGAGCTCATCACAGGAAATA GCTCGAGTTTGAGGCAGCACTTCTGAATGCAGAAGAGATTCATCTGTGTTAAAGCTGAAATGTCAAAAGGTATCAGATTTTTTTTATGAA AACGAAGAGAGATGTTTAAAGTTTATTTTTCAGCAGGTGAGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGAA TCACCTGAGGTCAGGAGTTCGAAACCAGCCTTCCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTAG CGCACACCTGTAATTCCAGCTACTCGGGAGGCTAAGGCAGGGGAATCGCTTGAACCTGGGAGGTGGAGGCTACAGTGAGCTGAGATCGTG CCATTGCGCTCCAGCCTAGGTGACAGAGCAAGACTCCATCTCAAAAAAATAAAAAAATAAAGTTTGTTTTTCTATAAAAAGTCATAACAA AGTATTAGTATGACTTTTTGAATAAGTTAATTTCTGCCAGTGTTTAATTATTTTATTAAAGAAAAGGATGTTACACTGAATCCTTAAAGA ATAAAAGTGATTTGACCTCTGCTTTGAGAAGACAGCCTGTAATTTTTAAAGCTATACTTCAAAGAGGGGATTTTGAATTTTATAAATGCT TGTTAATGTCTATTTTTGTAAGGTTTTTGTGTTTTCCTTTCATTGTTGTCAAGAGGCTATTTTTGCTCCACATAGGCCTGCATTTATTTT AAAGGTCAGAATTTTACTCTTAATGGTCATATATTAGTTGGGGTTGTAGCTGACAAAAGTCATGAAATTTCGTGGTTTTCACAGTTAAAA TTTCCGTCTGTTCCTTTAAAACTCTCCTGCATGCCTGGGGCTCTTGGGATCTGCTCTGTGGCCTAGGATGTGGCTGTTTTATCTGCCGTA TAATGTACATCGTGCTGACAATGCCTTGGTTTTGTCTGAAACATTTACACTTCTATTTTCCACCAGTGTTCTTTAGAATTGTTTCTGTTT TAGGTGACTTAAAGTTTTAACTAAAGCATGAGTAACGTTTGTTGGCATACAGTCCCTTCACCACAAATAATTGTCTTGCACTGTCTACAA AGCAAGGATCAGTTACCTCACTTGTCCCCTTCCCTACCCAAATAAACCTTACAACGCTATTCTTTGAGACTATCCTGAACTTGAAATCCC ACGTTTAGATCCAAGCTGGACTCAGGCAAGCGCTGCTCCAACAAAGCGTTCTCTTCCTGGTTCCCCTTAATCTTTATCCACCTCTCCAAG GCCTATCTTTGGGGATTCCTTTGGTTATAGGCACCTCTGCTTGTTTATGCAGGGGGCATTGGCCGGAAGGACATTGGTCTGGGGAATATC CCTGAACCCCATGCCTCTGGGGGCACAGGGAGGGGCAGCGAGCAGGTGGGGTGGATTTCCACGGCTTCATCCCTGGCTCCAGGCCTAAGC TGCCTCCCAGGTTCTTAGGGCCCAGCAAGTCAATACATACTACGTCAGGTGGCGACAAATGCTCCAAAGCCGAGTTCCAGCTCAGTCAAG TGAGGACACATTTTCAGCACCTCACCTTCTTTTCTGCATCTCTGGAGCTCATCAGTCTTGCTTTTCTTTGTTCTCCCTTTTAAATCCACT GCCCTGACCTTGTTCGTGTATTTTCCAGTCACTTAGTGTGGAGGAAGGGAATCTCATCCCATGGAGAATAGATCGAACATGGTCTTCACC TGACTTAAAATATAAAATGCTAAATTAGAAATATCTTAAGTGGGGCGGGGGGCACAGTTATTTTAAAAATAAAACCTATCAACTCCCTCC TTGCCTGAAAGCTGTAGGGGACATATGGGTCTTCTGAGATTTGCTGTGTGATGCTGTCTCCTCTCCAGGGACAAGGCTGCTGGGCACTAG AGGACTAGATCTTTCAAGGGTCCCAGATCCACTGTCACATAAAGTCACATCCAGAAGACCTTTCCTGCCAGCTTCCAGGGCTCTTTGTGT TCTGTGACAGCATTTGGGCATAGATCCTGCTTACCCGGCCTGGCTGCTGACAGGCGTTGGCTGCCTGCCCTCCAGGGGAGACACTTTCTT GGGCTCTGTCTTTGAAAGGCTGTGGGGAGGTTGAAGGTGCAACTCAGGTCCCCAGACTGCAGTGAGCTGACCTGGCAGGGCAGATGCCAT CACATCTGGGGGAGCCGGCGGGTGTTAGTGGAGCTTGGATGGGAACTTACCCAGCATCCTAACAAAGGTACAGAAGGACCAGGTGAACTC AGGGCTGATAACGCATTACACAGTAATGGTAAAGTGGCATAGTAAAGATTAGTAAGCAAACAGCTTTTCCTCTTGATTTGCATATATTTT ATTTTCCTACTCTTCCCTGAGCAAATATAAGCAGTAAGCAAGCAGGCTAGGTGTGCTCAATAAACTCAGCAACACCTGGGATGACCTCTG CACTCGAGGGGCCACTGCAATCTTTGTCAAAGGCATAGGATGCTCCTGCTCTAGTTGCACTTGACCTAGGTGCCCTTTCTGCTACATGCA AATGGCCTCTAAGAAGAACGAGGAACGTATGTGTCCAGGTTGGCTTGATTTCACCAGTTCACTCAGCTATGGCCACGATTTACTGACATC AGCTCTGCAATTGAGAGGTCCTGTCTCCAGGGGGAGGCTCGCTGGGCTTGCTCCTGACGAGGGGACCCCCATTGAGGGTCAGTTCCCAGA GGAGAGTGGGGTGGGTCTGGAAACCCCCGAGGGGCAAGGTGGAGGAGCTCTCCTGTCGTAGCGGCTGGTCAGGGCCAGTTCTGCTCCCTG GCTCCACTGAGCTCGCCTGAGCCTGTGAGGTTGCCAGGGGTTCCCTGTGGCACGGCAGGCACTTCTGGATGCAGAGGTGGAGGTTGAGGC CGTGACTCCAGGGGCATGTTTGGTGGTGCTTGGGGCTGTTCCTGTGAACAGAGCAGAGTGGGAGGCAGGCATCATAGTTGCTGCAGAACA GTCCATACTGTGGGGCTGGGGGGTTTCCTGCCACACCTGCCATCTGCCCGGACCCCATAGGGAAGGCCACACAGGCAAATTCCTGAGAAG GGTCAGCCAGCTCACAAAGGTGGCCATTCTAGAGAAATCTCAGAGGAGAGGAAGTGCTTTGTCAGGAACTAGGCCTCAGGTCTTTCCCTG GAGGCCACTTCTTCCTACATTGATTTAGGATGGGGGGGGTGGGGGGTGGAGGGGAGCAGGTTGACCTCCCATCCAGCGCTGTATCTGAGT GTAGTTCATTTTATATCCATAGCCCAAGCCAACTTGTATCTTGGTGATATGGTTTGGCTGCGTCACGACACAAATCTCACCTTGAATTGT AATAATCCCCACGTGTCGTGGGAAGGACCCAGTGGGAGGTAATTGAATCATGGGGGCGGGTCTTCCCATGCTGTTCTCGTGATAGTAAGT CTCATGAGATCTGATGGTTTTATAAAGGGGAGTTTCCCTGCACATGCCCTTTTGCCTGTGTCATGTAAGATGTGGCTTTGCTCTTCCTTT >In-frame_C21orf59_ENST00000540881_chr21_33979959_-_URB1_ENST00000382751_chr21_33750850_-_10699nt AGAATCAGCTGTCCTCTCAGACTGTGTGGGTGGTTTCCCCGGCCGCAGCTCCGTACGGGCTTGGATTGCTGGGCCTCGGTGCACCCCAGC CTCCCCCACTCGGGTTCTGAGCTTGAGCTGGCGGCTCTTTAACTCTGCTTCACTGTTGCTCTTGGCAACATCCACTTCCGGGAGCGAGTG CCGTTTCCCCCGCTCACCGCGGGCTAGGGAGCGTGGGATTCCGGACTGTGAGCGGCTGTTAGTGCGTCGCAGCTGCTGGCGATCCGGCGA CCCTCGGCCGGCAGGACCCGCGGGCCACGCAGCCGGGGCCTTCTCAACGCCTCAGTACCTCGGCGGGACCGCCATGGTTCTGCTGCACGT GAAGCGGGGCGACGAGAGCCAGTTCCTGCTGCAGGCGCCTGGGAGTACCGAGCTGGAGGAGCTCACGGTGCAGGTGGCCCGGGTCTATAA TGGGCGGCTCAAGGTGCAGCGCCTCTGCTCAGCTCCAAATGAGAAGATGAAGCAAGTGTTAAAGAAGACTATAGAAGAAGCCAAAGCAAT AATATCTAAGGGAGTGTACGACGTTCGGCAGGCCTACGTTCAGTTTGCTCTCTCCTTTTTAATTGCGGGTGATGACAGCACTATAGTGCA GGTGTTGGAAGTGAAAGAATTTATTCCTTGCATTTTTAGCTCAGGGATAAAGGAAGATAGGATCTCTACCATCAATATTTTATTATCCAC ACTGAAAACAAAGGTAGTTCACAATAAAAATATCACAAAAACCCAGAAGGTGCGTTTCTTTACGGGGCAGTTATTGAACCACATAGCATC GCTGTACAACTGGAATGGGATTACCGATGTGAACCCAGAAAATGTCAAGGTTTCTGCCGAAGAAGCAGGGAAAACCATGGTGCGGGAGCT TGTTCATAACTTCCTGATGGATCTTTGCTGTTCACTCAAGCATGGAATTAATTTTTACGATGCATCTTTGGGTACCTTTGGCAGAGGCGG AAACCTGACACTCTTGCACTTCTTGCTGGGTTTGAAAACTGCAGCTGATGATGATCTGGTGGCTGACCTTGTGGTAAACATCCTCAAAGT GTGCCCGGACTTACTGAACAAATACTTCAAGGAAGTAACGTTTTCCTTTATCCCACGAGCGAAGTCTACTTGGTTAAATAATATCAAACT ACTAAACAAGATCTATGAGGCTCAGCCGGAGATTTCCCGGGCATTTCAGACCAGAGAGTTTATACCCTTGCCTCGGCTCCTGGCAATGGT GATGGTGACCACCGTGCCCCTGGTGTGCAATAAGAGCATGTTCACCCAAGCATTAAACTTGGACAGCACCTCAGTGAGGCACACAGCCTT ATCCCTTATTTCTGTCATTTTGAAGAGGGCATTAAAAACTGTTGACCACTGCCTGAATAAAGAGGTGTGGCAGGAATCAGGCGTGTACAC AGCTGTGATGATGGAAGAATTCGTGCAGCTCTTCAGAGAAGCCCTGAGCAAGATTTTGCCAGACCTGAACACTGTCGTGTGGGTCTGGCA GTCACTTAAAAAGCAAGAGACCAAACAGGATGACAAGAAAGGGCAGAAAAGGAGCGATGGGCCCCCGGCTGCCTGCGATGCTCACCAGTG CGATGATGCAGAAACCATTCTTTTGAAAGCTGTTTTGCTCCAGGTCATATGCCTCTACCAGAAGGTGGTCCCCCACGTGGTCATGCAGTA CAACTTTGACTTCAGCAAGCTCCTGAAAGGTGTCATCTCTGAGCAGGGCCTTCGAGAGGAGGTGCCTCCCATTCTGCAGCACCACATGCT GAAGGTGGCCCTGGAGCTGCCGGCCAGCAAGTTTCTGTGGTTAAAGGCACAGGAAGGCCCAGATGCAGAAATTATTGGAGGTGAACGATC AGTATTTTACTTACTAATGAAAATGTTTGTGACCAGTAGCCATTTACAACTGAAGTCATTGACCAAACTTCTGATCATGAAGATTCTGCG GGACACGGGGGTGTTTGAGCACACCTGGAAGGAGCTGGAGCTCTGGCTGGAGCATTTAGAGAACACCATGGAAGAGGACAAAGAGACTGT GATTCAGTTTCTGGAACGCATTTTATTGACATTGGTGGCGAATCCCTATTCATACACAGACAAAGCATCTGACTTTGTCCAAGAAGCAAG CATGCTGCAGGCCACTATGACGAAGCAAGAAGCCGATGACATGAGCATTCCCATCTCCCACATTGACGATGTTCTCGACATGGTGGATGT CCTGGTGGAGGGCAGTGAAGGCTTGGATGAGGAAATAGGGTTCACGTTGAGTGAAGACATGATCCTGCTCACGTTCCCATTCAGTGCGGT AGTCCCTGCGGCCCTGGAAGCCAGGAATAAGTTGCTCCTTGGGACAGGCAATGAAGCAGCGGAAAACGTTGTGACATATCTGACGGCAGT GCTGACTGACCTCCTCCACACCCAGAGGGACCCCCTGGCTCTGTGTCTCCTGCTCCAGGCATATGATAAGCTTGAGCCTCCATGCCTGGT GCCTTGCTGCCAGCAGCTCTCACGGTTTAACAGATACTACAGCCTCTGGATCCCGGAGCAAGCCCGAGAGGCCTGGCTGCTGCAGGCACA GGGCAGCCCCTCGCCCCCTGCCCTTCCCTTGGCCTCGTCCTTCACAGCCCTGCTGCAGGCAGCCTACGAGAGCCAAGCGCTTCGGGACGA GCACATCCAGGTGCAGCTGCAGGCCACCATGCCACACCTGTCCATGCAGCAGGTCCTGCTCGCGGCCAAGCAGGTGTTGCTCTACCTGCG GAGCACTGTGGAGAACTTCGGCCAGCTGGGCAGAAGTGTGGGCCCGCCCCTCCTGCAGCTCTTCCTGGATCTCCTCAGGCGCCTGGTTGT CCACTGTGAGCAGCTGGATGCCCAGAACCAGCAGAGATGCGAGGCCGCCCGGGCCGAAGCCGACCTCTTCCTGGACATGGAGTCCGTGGC CTCGCTGGAGTTGGCCAATGATCAGACGCTGGAGGAGGTGCTTGTGGCCATCCTCAGGCACCCCACCCTGGAGGGCTGGTTCCTGGCCCT GGAGCAGCAGGCCCTCCCGCCGCACACGCTCAGCCCTGTCCTCGTGAAGCTCCTGGCCACCCACTTTAGTGCAGGGGTCCTTCAGCTGCT GGCAGCAAGTGCCCCGATCCTCCAGAACATTGGGCAGCTGGGCCTTCTGGCCAGGTACTCAGAGGCCATCACCCAGAGTGTGCTGAAGGA ACTTCAGAACAGGAGGGCGGGCCCGGCCACATCACCACCAAAGACCCCGCCGCAGCTGGAGGCCCTGCAGGAGCTGCATCCATACATGGA GGGTGCCCAGCTCCGTGAGGTCACCCTGGCCTTGCTGAGCCTGCCTGAGACACACCTGGTGACCCAGCAACCCACGAAATCCCCCGGGAA GGAAAGACACCTGAATGCTCTTGGAAAGACCCTGGTGCAGCTGCTGACCTGCAGCCCCCAGGATCAGCTGCAGAGTGGTGAGCTCCTGTG GTCCTCCGAGTATGTGAGAGGCCTGGGGGCTCTGCTGCCCACGCTAGCAGTGGACGAGCTGGACACAGTGCTCCTCCACACTCTGCAGAG AGACCCTGTGCTGGCCCCCGCAGTCGGGGCTGATCTGCTTGACTACTGCCTGGCCCGGCGCACACAGGCGGCCCTCAGCATCGCTGCCCT GCTCCTCCAGGAGAGCTGCACCCACTTGCTGTGGTTCGAGCAGTGGTGCCTGCAGGCTGGCCCAGGGCTCGGCCTCCAGGGGGACCTGGA CGACTTCCTTCCCCTCATCCATGTGTACCTCCAGTGCAGGACACGGAGCCACTTCACACGCCCAGCAGGAGTGTCTTCCGCTGTCATTCC TGTCTTGAGGAAGACCCTGTGGAGGCAGCTACAGAGCAGGCTTCTTAGCACTGACAGTCCCCCAGCATCTGGGCTGTACCAGGAGATCCT GGCACAGCTGGTCCCGTTTGCACGAGCCAAGGATCTCAGTGTACTCATGGACCGCCTGCCCAGCTTGCTTCACACCCCAAGCAGTCACAA GAGGTGGATCGTGGCCGACTCCATTTCAGCAGCTCTGGAAGGGTCAGCAGAAGAGCTGTGTGCCTGGAGAAGGACCCTTTTGGAGTCCTG TGTGAAGTGGCTGATCGTGTCTTTCAGTGGTGGACAGCAAGATGATGATAATACTCAGAATCAGGAGAAGGAAATGCTGCTTAGATTAAA TGCGTTGTTGCATGCACTTAATGAAGTTGATCCTGGTGACTGGCAGAAATTCGTGAAGAAGGGACTCAAATTTCGGTACCAGGACCACAC ATTTTTAAAGATGCTCCTCACCGCCGTACAGCTCCTGTACAGCCCAGAAAGCTCCGTGCGCACGAAGCTCATCCAGCTCCCGGTGGTCTA CGTGATGCTCATGCAGCACTCGCTGTTTCTGCCGACTCTACTGACGTCTGACGGAGAGGAGAGCCCGGACAGCCAAGTAAAAGAAGCGCT GGTGGACCTGATGCTGACGGTGGTGGAGATGTGCCCCTCTGTCTGTGAGAGCAGCCACTTTGCAGTGCTTCTCGGGGCCTATGGCGCCAC TCTCAGCGTCCTAGATCAGAAGATTTTACTTCTGCTTCGAGCGTATGAGCAGAACAAGCTCAGCCTCATCAACTTCAGGGTGCTGCTGTG GGGCCCAGCGGCCGTGGAGCATCACAAGACGTGCCGGAGCCTGGGCAGGTCACTGTGGCAGCAGCCGAGTGTCGGGGACATCCTTCGCCT GCTGGACCGGGACCGGATGATGCAGACCATCCTGCACTTCCCCCAGAACCGGAGGCTGCTGCCCCCCGAGGACACACAGGAGCTGATATT CAAAGACAAAAGCAGGGTGGATCTTGATGGCCTCTATGACCCCTGCTTTCTCCTTCAGCTCTTCAGTGAGCTGACCAGGCCAGAGTTTGT GGTGGATTGTCGAAAATTTTTGGATTCAAATGCTCTGGGCCTAACTGTCACAGCCCTCAGCAGCTATGACCCCCAGATGCGAGCCATAGC CTACCATGTCCTGGCGGCCTACTACTCGCACTTGGAGGGCGCACGGTTCCAAGAGCAGTCCCAGCTACTTTACCTGTTGGATGTAGTCCG GAATGGGATTCGAACTCAGGACATGAGACTTACTTTTACCTTGGCTCTCTTCATTGCCAAAGCAGCCCTGCAGATTTTGAAACCAGAGGA GCACATGTACCTGAAGGTCAGCAACTTCCTGCTGTCGCATGAGTACTTGAACATGGACAAAGTGCCAGGCTTCTACCAGTTCTTCTACAG CTCCGACTTTGAGCAAAAAACAGAGCAGAAGTGGGTGTTTGGCGTTCTGCGGCAGGGGATCCGTGACAAGCAGTGCTACGAACTGTGTGC CCGGCGTGGCATCTTCCACATCATCCTGTCCTTCTTCCACAGCCCGCTGTGTGACGAGGCAGCACAGAATTGGATTCTGGAAATTCTACA GAATGCTGCCCAGGTTGCCAGATCTGCGTATGAAATCATACGAGACTATAGCCTTTTAACATGGATTTTACACATCCTTGAAAGCAAGTT TCTGGAGACTCCGCTGCTGTCTAATGTGATCTCCTTGCTACACACACTGTGGGTGACCAACCTGGGGGACAAGGCAGTGGAGTGGGAGAG CCAGCGCCTTTGCCAGCCTAGCTCCCAGGAGCCTGCCAAGCGGCTTGCCCTGCACCTGGTCAATGAGTTCCTTTATGTTCTCATCGTGCT CATGAAGCACCTGAGGCCCACCTTGGCCCCCGTCCAGCTGACCAACTTCTTCGGGACACTTGACTCCGTGCTGAGGTACCGGGCCACTGT CATACAGGCCTTTAGGGACATGAACAGATTCACCGTAAATGAGACAGTGCTTTCCACCAAGGACGTCCTTGTCCTCTTGCACAAGTGGAG CCTCATTGAAAGAGACCTCAAGCTCCAGGAAGACCTGAGAGCAGCCATTGAGAAGGCCCAAGCCCGGGAGCTCATGAAAATGCTCAAGGA TAAGAACAAGCCTGTCATGCCAGCCCGAGCCAAAGGCCCACGGGGCCGAAAGAGGAGGCCTGGGGAGGCAGAGGAGATGGCTGACCCTGA GCTGATGGCATCTACCTTGGAGACATGCAAGGGCCTCCTGAGGTCCATCTTGACTTACTGGAGACCAGTGATCCCTGGTCCTGACCCCAC TCAGGAGCCTGTGGACTCAGCCAGCCCCGAGAGCGATGCGCCAGGCCCCGTATATGCTGCCGCTTCCCTGGCAGTCAGTTGGGTGCTGCG GTCGGTGGCCGAGCACCCGCTCAGCAGGGCAGAGGCTGCAGGACTCATTGGCTGGCTTAAGAGCCATATTTTGCCACACCCTGTGGTCGT GGCTGACCTCCTTAAGGACAGTGCCGTGAGGAGCAGCATATTCAGGCTGTATAGCCGGCTCTGTGGGGCTGAGGGGCTGGCAGGGCCTGT GCAGGAGGTGGCCTGCCTGTTCAATACGGTCATGCTGCAGCTGGTGGCTGCCCAGGGCCGGGCAGGGAGCCCCTTCCACCCGGCCATGGA AGCCCTCTCCCTGTCTTCTCTGAGTGAGAAGGATGAAGCCACACAAGCCTCCGCAGCATTCCTAGTGTCTCTCTACATAAAGGACATCTG GCTGGGGGCTCAGCGGCCGGACACCCTCTTAACCCACGTCCGGATGGTGTGTGAGGCCGCAGATGATGCCCCGAGCAGTGAAGAGGAGGC CATCGTGGTGCTCTGCAAGGACGCCGCCAGCGCAGCCTCAGATGCTTGACTCCTGCCGGCCAGCACCTTGCACCCTGATGACCAGAGCCT CGAGCACAGCACCAGCTTCTAGAAGTTTGGTTGAGTCAAGGGTTTCCAGAGAAGGCATGGGAAACAACAGGTTCAGTACATTGGCTCAGT TCTTTGACAAGAAAAGTTGAGAGGACTTTATTGAACTGCCCAGTAAATGATAAACTCGGGCCTGTAGGTGCCCAGCATCAGAGTTGCAAG GAATGTGGGGACTTCTAGGCCATGAGGCCCATCCAGTGCCTCGTCAGGCCGCCCCTTCCTCTCTAGGGGCTTGGAGCTCATCACAGGAAA TAGCTCGAGTTTGAGGCAGCACTTCTGAATGCAGAAGAGATTCATCTGTGTTAAAGCTGAAATGTCAAAAGGTATCAGATTTTTTTTATG AAAACGAAGAGAGATGTTTAAAGTTTATTTTTCAGCAGGTGAGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCAAGGCGGGTG AATCACCTGAGGTCAGGAGTTCGAAACCAGCCTTCCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCATGGT AGCGCACACCTGTAATTCCAGCTACTCGGGAGGCTAAGGCAGGGGAATCGCTTGAACCTGGGAGGTGGAGGCTACAGTGAGCTGAGATCG TGCCATTGCGCTCCAGCCTAGGTGACAGAGCAAGACTCCATCTCAAAAAAATAAAAAAATAAAGTTTGTTTTTCTATAAAAAGTCATAAC AAAGTATTAGTATGACTTTTTGAATAAGTTAATTTCTGCCAGTGTTTAATTATTTTATTAAAGAAAAGGATGTTACACTGAATCCTTAAA GAATAAAAGTGATTTGACCTCTGCTTTGAGAAGACAGCCTGTAATTTTTAAAGCTATACTTCAAAGAGGGGATTTTGAATTTTATAAATG CTTGTTAATGTCTATTTTTGTAAGGTTTTTGTGTTTTCCTTTCATTGTTGTCAAGAGGCTATTTTTGCTCCACATAGGCCTGCATTTATT TTAAAGGTCAGAATTTTACTCTTAATGGTCATATATTAGTTGGGGTTGTAGCTGACAAAAGTCATGAAATTTCGTGGTTTTCACAGTTAA AATTTCCGTCTGTTCCTTTAAAACTCTCCTGCATGCCTGGGGCTCTTGGGATCTGCTCTGTGGCCTAGGATGTGGCTGTTTTATCTGCCG TATAATGTACATCGTGCTGACAATGCCTTGGTTTTGTCTGAAACATTTACACTTCTATTTTCCACCAGTGTTCTTTAGAATTGTTTCTGT TTTAGGTGACTTAAAGTTTTAACTAAAGCATGAGTAACGTTTGTTGGCATACAGTCCCTTCACCACAAATAATTGTCTTGCACTGTCTAC AAAGCAAGGATCAGTTACCTCACTTGTCCCCTTCCCTACCCAAATAAACCTTACAACGCTATTCTTTGAGACTATCCTGAACTTGAAATC CCACGTTTAGATCCAAGCTGGACTCAGGCAAGCGCTGCTCCAACAAAGCGTTCTCTTCCTGGTTCCCCTTAATCTTTATCCACCTCTCCA AGGCCTATCTTTGGGGATTCCTTTGGTTATAGGCACCTCTGCTTGTTTATGCAGGGGGCATTGGCCGGAAGGACATTGGTCTGGGGAATA TCCCTGAACCCCATGCCTCTGGGGGCACAGGGAGGGGCAGCGAGCAGGTGGGGTGGATTTCCACGGCTTCATCCCTGGCTCCAGGCCTAA GCTGCCTCCCAGGTTCTTAGGGCCCAGCAAGTCAATACATACTACGTCAGGTGGCGACAAATGCTCCAAAGCCGAGTTCCAGCTCAGTCA AGTGAGGACACATTTTCAGCACCTCACCTTCTTTTCTGCATCTCTGGAGCTCATCAGTCTTGCTTTTCTTTGTTCTCCCTTTTAAATCCA CTGCCCTGACCTTGTTCGTGTATTTTCCAGTCACTTAGTGTGGAGGAAGGGAATCTCATCCCATGGAGAATAGATCGAACATGGTCTTCA CCTGACTTAAAATATAAAATGCTAAATTAGAAATATCTTAAGTGGGGCGGGGGGCACAGTTATTTTAAAAATAAAACCTATCAACTCCCT CCTTGCCTGAAAGCTGTAGGGGACATATGGGTCTTCTGAGATTTGCTGTGTGATGCTGTCTCCTCTCCAGGGACAAGGCTGCTGGGCACT AGAGGACTAGATCTTTCAAGGGTCCCAGATCCACTGTCACATAAAGTCACATCCAGAAGACCTTTCCTGCCAGCTTCCAGGGCTCTTTGT GTTCTGTGACAGCATTTGGGCATAGATCCTGCTTACCCGGCCTGGCTGCTGACAGGCGTTGGCTGCCTGCCCTCCAGGGGAGACACTTTC TTGGGCTCTGTCTTTGAAAGGCTGTGGGGAGGTTGAAGGTGCAACTCAGGTCCCCAGACTGCAGTGAGCTGACCTGGCAGGGCAGATGCC ATCACATCTGGGGGAGCCGGCGGGTGTTAGTGGAGCTTGGATGGGAACTTACCCAGCATCCTAACAAAGGTACAGAAGGACCAGGTGAAC TCAGGGCTGATAACGCATTACACAGTAATGGTAAAGTGGCATAGTAAAGATTAGTAAGCAAACAGCTTTTCCTCTTGATTTGCATATATT TTATTTTCCTACTCTTCCCTGAGCAAATATAAGCAGTAAGCAAGCAGGCTAGGTGTGCTCAATAAACTCAGCAACACCTGGGATGACCTC TGCACTCGAGGGGCCACTGCAATCTTTGTCAAAGGCATAGGATGCTCCTGCTCTAGTTGCACTTGACCTAGGTGCCCTTTCTGCTACATG CAAATGGCCTCTAAGAAGAACGAGGAACGTATGTGTCCAGGTTGGCTTGATTTCACCAGTTCACTCAGCTATGGCCACGATTTACTGACA TCAGCTCTGCAATTGAGAGGTCCTGTCTCCAGGGGGAGGCTCGCTGGGCTTGCTCCTGACGAGGGGACCCCCATTGAGGGTCAGTTCCCA GAGGAGAGTGGGGTGGGTCTGGAAACCCCCGAGGGGCAAGGTGGAGGAGCTCTCCTGTCGTAGCGGCTGGTCAGGGCCAGTTCTGCTCCC TGGCTCCACTGAGCTCGCCTGAGCCTGTGAGGTTGCCAGGGGTTCCCTGTGGCACGGCAGGCACTTCTGGATGCAGAGGTGGAGGTTGAG GCCGTGACTCCAGGGGCATGTTTGGTGGTGCTTGGGGCTGTTCCTGTGAACAGAGCAGAGTGGGAGGCAGGCATCATAGTTGCTGCAGAA CAGTCCATACTGTGGGGCTGGGGGGTTTCCTGCCACACCTGCCATCTGCCCGGACCCCATAGGGAAGGCCACACAGGCAAATTCCTGAGA AGGGTCAGCCAGCTCACAAAGGTGGCCATTCTAGAGAAATCTCAGAGGAGAGGAAGTGCTTTGTCAGGAACTAGGCCTCAGGTCTTTCCC TGGAGGCCACTTCTTCCTACATTGATTTAGGATGGGGGGGGTGGGGGGTGGAGGGGAGCAGGTTGACCTCCCATCCAGCGCTGTATCTGA GTGTAGTTCATTTTATATCCATAGCCCAAGCCAACTTGTATCTTGGTGATATGGTTTGGCTGCGTCACGACACAAATCTCACCTTGAATT GTAATAATCCCCACGTGTCGTGGGAAGGACCCAGTGGGAGGTAATTGAATCATGGGGGCGGGTCTTCCCATGCTGTTCTCGTGATAGTAA GTCTCATGAGATCTGATGGTTTTATAAAGGGGAGTTTCCCTGCACATGCCCTTTTGCCTGTGTCATGTAAGATGTGGCTTTGCTCTTCCT |
Top |
FusionGenePPI for C21orf59_URB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| C21orf59 | MAPK6, APP, LYN, BAG3, PEX7, JUP, HAL, CALML5, TGM1, ASPRV1, TGM3, RNASE7, FLG, GM2A, POF1B, CDSN, SERPINA12, SERPINB8, CPA4, SERPINB2, NCCRP1, ECM1, GLRX, SERPINB7, KLK5, DUSP12, HNRNPH1, PLXNB1, STK3, AKR7A2, MAU2, PGAP2, ILKAP, C21orf59, CTNNA1, CTNNB1, HSPBP1, HSPA8, ARG1, DSG1, RNF111 | URB1 | MAPK6, TAB1, SIRT7, LGR4, NXF1, OBSL1, RPL10A, RPL14, NPM1, IFI16, SORT1, CDC23, KIF14, TFG, NOP56, NLRP3, BAG6, NOL8, MECP2, RPL18A, CCDC59, RRP8, FGF3, H2AFY2, FGF8, ZNF512, PLEKHO1, RBM34, RPL18, RBM4 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for C21orf59_URB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for C21orf59_URB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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