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Fusion gene ID: 4869 |
FusionGeneSummary for C1orf213_PTCH2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: C1orf213_PTCH2 | Fusion gene ID: 4869 | Hgene | Tgene | Gene symbol | C1orf213 | PTCH2 | Gene ID | 8643 |
| Gene name | patched 2 | ||
| Synonyms | PTC2 | ||
| Cytomap | 1p34.1 | ||
| Type of gene | protein-coding | ||
| Description | protein patched homolog 2patched homolog 2 | ||
| Modification date | 20180523 | ||
| UniProtAcc | Q9Y6C5 | ||
| Ensembl transtripts involved in fusion gene | ENST00000458053, ENST00000454117, ENST00000335648, ENST00000518821, ENST00000437367, | ENST00000447098, ENST00000372192, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 2=8 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: C1orf213 [Title/Abstract] AND PTCH2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-EB-A82C-01A | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000458053 | ENST00000447098 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| intron-3CDS | ENST00000458053 | ENST00000372192 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| Frame-shift | ENST00000454117 | ENST00000447098 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| Frame-shift | ENST00000454117 | ENST00000372192 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| In-frame | ENST00000335648 | ENST00000447098 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| In-frame | ENST00000335648 | ENST00000372192 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| intron-3CDS | ENST00000518821 | ENST00000447098 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| intron-3CDS | ENST00000518821 | ENST00000372192 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| Frame-shift | ENST00000437367 | ENST00000447098 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
| Frame-shift | ENST00000437367 | ENST00000372192 | C1orf213 | chr1 | 23696006 | + | PTCH2 | chr1 | 45292440 | - |
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FusionProtFeatures for C1orf213_PTCH2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| C1orf213 | PTCH2 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | May have a role in epidermal development. May act as areceptor for Sonic hedgehog (SHH). |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for C1orf213_PTCH2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_C1orf213_ENST00000335648_chr1_23696006_+_PTCH2_ENST00000447098_chr1_45292440_-_1077aa MLAVPVRLKVGSRKPEWGTNRLTSCPAKDPLDRRLQNLRDRERVPEPQRSLRPGVQEDSREHGQVPEVSDPQVDLEFVDLQAKPRYRRLI LKTQIPEASDSQAAQKPQAHRQIPETTEAGRETTSNXAAFSWSSSEREDSQLSLSPARMRELDNGSRALGKAGILRGEELPARCSLGEGS DGKRIXQLIRDSHPLQVINIPRTLATCPEACCLXLYRRLLCLGWERGLSFVLQIDPPTEELENFFQTXLQALLLLVSVLFPVPGYLXLNY XSVXKEQKDPPQPXCRLSHSFSFHPQLWGXEFLRCHRIIPSYLIXSRSEAGPMVVGYQNLITLITLKLVYNPPLLNLAIKIKLIXAPYKM ESWRVPXRQYPQWKERGPQGQTSLVWNPGCVSFGKSLNPGPFPFLXNEGHHTXGCCEAXVRXLKRSRECALGXXPLLFINPGFGGKGNFQ KCLWVYWIAQKIWEIKVAQXLXGTVGDFILTSCFFQKFRRNRGXASLVGSSERCVEPSRAXVLGVAKTPASXGFTLRETSGSEVNNHAPW SKEEGSLSDXLKXLQVSNWAXGELRAXAPQPSGGPFSSLLXQIALXTFLGLPPTPLPQCFKPFFVFLLFLLFLRPAGRGRGGAQDDSPGS AWLPASFCKCFFFLHLGPSRGWKEKRGWERMESMTASGAPGGSGEEGVEGQWLRGFLLQPSAGLRVGVTGGGGGFLPHCSGLQCFLGILT VCGFSVTNLESCICSHDSANNEYLLCVEAAGQPVITGKEARRAVWPGSPIXAFNIISKEGYTLCRLHWLMGSKTLLVYPXTCTLLPGHCA CGALXVPTFXXILXLSCELPPAQPLEFAQFPFLLRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCI LLVCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFA >In-frame_C1orf213_ENST00000335648_chr1_23696006_+_PTCH2_ENST00000372192_chr1_45292440_-_1134aa MLAVPVRLKVGSRKPEWGTNRLTSCPAKDPLDRRLQNLRDRERVPEPQRSLRPGVQEDSREHGQVPEVSDPQVDLEFVDLQAKPRYRRLI LKTQIPEASDSQAAQKPQAHRQIPETTEAGRETTSNXAAFSWSSSEREDSQLSLSPARMRELDNGSRALGKAGILRGEELPARCSLGEGS DGKRIXQLIRDSHPLQVINIPRTLATCPEACCLXLYRRLLCLGWERGLSFVLQIDPPTEELENFFQTXLQALLLLVSVLFPVPGYLXLNY XSVXKEQKDPPQPXCRLSHSFSFHPQLWGXEFLRCHRIIPSYLIXSRSEAGPMVVGYQNLITLITLKLVYNPPLLNLAIKIKLIXAPYKM ESWRVPXRQYPQWKERGPQGQTSLVWNPGCVSFGKSLNPGPFPFLXNEGHHTXGCCEAXVRXLKRSRECALGXXPLLFINPGFGGKGNFQ KCLWVYWIAQKIWEIKVAQXLXGTVGDFILTSCFFQKFRRNRGXASLVGSSERCVEPSRAXVLGVAKTPASXGFTLRETSGSEVNNHAPW SKEEGSLSDXLKXLQVSNWAXGELRAXAPQPSGGPFSSLLXQIALXTFLGLPPTPLPQCFKPFFVFLLFLLFLRPAGRGRGGAQDDSPGS AWLPASFCKCFFFLHLGPSRGWKEKRGWERMESMTASGAPGGSGEEGVEGQWLRGFLLQPSAGLRVGVTGGGGGFLPHCSGLQCFLGILT VCGFSVTNLESCICSHDSANNEYLLCVEAAGQPVITGKEARRAVWPGSPIXAFNIISKEGYTLCRLHWLMGSKTLLVYPXTCTLLPGHCA CGALXVPTFXXILXLSCELPPAQPLEFAQFPFLLRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCI LLVCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFA PVTDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPPPEVIQMYKESPEILSPPAPQGGGLRWGASSSLP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_C1orf213_ENST00000335648_chr1_23696006_+_PTCH2_ENST00000447098_chr1_45292440_-_3231nt ATGTTAGCAGTCCCTGTCCGGTTGAAGGTAGGAAGCCGAAAACCCGAGTGGGGGACGAACAGACTTACCTCCTGTCCCGCAAAAGATCCA CTAGATCGTCGTCTCCAAAACCTGAGAGACCGCGAACGGGTTCCAGAGCCGCAGCGTTCTCTCAGACCTGGCGTTCAGGAAGATTCTAGA GAGCACGGGCAGGTCCCGGAGGTCTCAGACCCGCAGGTAGATCTCGAATTCGTAGACTTGCAGGCGAAGCCCAGATATCGTAGGCTGATC CTAAAGACTCAGATTCCCGAGGCCTCAGACTCGCAGGCAGCTCAGAAACCACAGGCTCATAGGCAGATCCCTGAGACCACAGAGGCTGGC CGAGAAACCACCAGCAACTAAGCTGCATTCAGCTGGAGTTCCTCGGAACGGGAGGACTCGCAGCTCTCCCTTTCCCCAGCCAGGATGAGG GAATTAGACAATGGAAGTCGAGCACTGGGGAAAGCAGGCATTCTGCGTGGGGAAGAGCTCCCAGCTCGCTGTAGCCTTGGAGAGGGAAGT GATGGAAAAAGAATATAGCAGCTTATTAGGGACTCCCACCCTCTTCAAGTTATAAATATCCCCAGAACCTTGGCTACGTGCCCGGAAGCC TGTTGTCTCTAACTGTACAGGAGACTTCTCTGCCTGGGCTGGGAAAGGGGCCTTTCTTTTGTTTTGCAGATAGATCCACCCACTGAGGAA CTTGAAAATTTTTTTCAAACATAACTCCAGGCCTTGCTTTTATTAGTGAGTGTCCTGTTCCCAGTGCCCGGTTATTTATGATTAAATTAC TGAAGTGTCTAAAAAGAACAGAAGGACCCACCCCAGCCATAATGCAGACTTTCCCATTCCTTCTCTTTCCACCCGCAACTGTGGGGCTAA GAATTCTTAAGATGTCACAGAATTATACCATCCTACCTCATCTAAAGTCGATCCGAGGCTGGTCCGATGGTAGTGGGTTACCAGAACTTA ATAACATTAATAACTCTAAAGTTAGTATACAACCCCCCACTGCTAAATTTGGCTATAAAAATAAAATTGATCTGAGCACCATATAAAATG GAATCCTGGAGGGTCCCCTAGAGGCAGTATCCCCAGTGGAAAGAGCGTGGGCCTCAAGGTCAGACAAGCCTGGTTTGGAATCCAGGCTGT GTATCCTTTGGAAAGTCATTGAATCCAGGCCCATTTCCTTTTCTCTAAAATGAGGGTCATCATACCTAAGGATGTTGTGAGGCGTGAGTG AGATGATTAAAGCGTTCCAGAGAGTGCGCTCTTGGATGATAGCCGTTACTTTTTATTAACCCTGGCTTTGGTGGTAAGGGAAACTTCCAG AAATGCTTGTGGGTATATTGGATAGCTCAGAAAATCTGGGAAATCAAAGTGGCTCAATAGCTGTGAGGAACTGTGGGTGACTTTATCCTC ACATCGTGTTTCTTCCAGAAATTCAGACGCAACAGAGGTTAGGCCAGTTTGGTGGGTTCCAGTGAGCGGTGTGTTGAGCCTAGTAGAGCA TAGGTACTTGGGGTTGCCAAAACCCCAGCAAGTTGAGGCTTCACGCTCAGGGAAACTTCTGGGTCAGAGGTTAATAACCACGCTCCTTGG AGCAAGGAGGAGGGGAGCCTTTCTGACTAGCTGAAGTAATTGCAGGTTTCTAACTGGGCCTAAGGTGAGCTGAGGGCTTGAGCCCCTCAG CCCAGCGGGGGTCCCTTTTCATCCCTTCTCTGACAGATTGCTTTGTAAACTTTCTTAGGCCTTCCCCCCACCCCTTTGCCCCAGTGCTTT AAGCCCTTCTTTGTCTTCTTGCTGTTTCTTTTATTCCTCAGGCCTGCGGGGCGGGGGCGGGGTGGCGCCCAGGACGACTCCCCGGGCTCA GCTTGGCTGCCTGCCTCCTTCTGTAAGTGCTTTTTTTTTCTTCACCTGGGACCCTCTAGAGGTTGGAAAGAGAAGAGAGGCTGGGAGCGG ATGGAAAGCATGACTGCATCTGGAGCCCCTGGGGGGAGTGGGGAAGAGGGAGTGGAAGGACAGTGGCTGAGGGGCTTCCTGTTGCAGCCT TCAGCTGGACTCAGGGTTGGGGTCACTGGAGGAGGAGGTGGCTTCCTGCCCCATTGTTCTGGACTGCAGTGTTTCTTGGGAATACTTACT GTATGTGGATTTTCAGTAACCAACTTGGAAAGCTGTATTTGTTCCCATGATTCAGCAAACAATGAGTACCTACTGTGTGTAGAAGCAGCA GGACAGCCTGTCATCACTGGGAAAGAGGCCAGAAGAGCCGTTTGGCCAGGGTCTCCAATTTAGGCTTTCAACATTATCTCTAAAGAAGGT TATACATTATGTCGGCTCCACTGGCTGATGGGATCAAAGACCCTCCTTGTATATCCTTAAACCTGTACTCTATTACCAGGCCACTGTGCC TGTGGAGCACTGTAAGTTCCTACCTTTTAATAAATTTTATAATTATCTTGTGAGCTCCCGCCAGCTCAGCCCTTGGAGTTTGCCCAGTTC CCCTTCCTGCTGCGTGGCCTCCAGAAGACTGCAGACTTTGTGGAGGCCATCGAGGGGGCCCGGGCAGCATGCGCAGAGGCCGGCCAGGCT GGGGTGCACGCCTACCCCAGCGGCTCCCCCTTCCTCTTCTGGGAACAGTATCTGGGCCTGCGGCGCTGCTTCCTGCTGGCCGTCTGCATC CTGCTGGTGTGCACTTTCCTCGTCTGTGCTCTGCTGCTCCTCAACCCCTGGACGGCTGGCCTCATAGTGCTGGTCCTGGCGATGATGACA GTGGAACTCTTTGGTATCATGGGTTTCCTGGGCATCAAGCTGAGTGCCATCCCCGTGGTGATCCTTGTGGCCTCTGTAGGCATTGGCGTT GAGTTCACAGTCCACGTGGCTCTGGGCTTCCTGACCACCCAGGGCAGCCGGAACCTGCGGGCCGCCCATGCCCTTGAGCACACATTTGCC CCCGTGACCGATGGGGCCATCTCCACATTGCTGGGTCTGCTCATGCTTGCTGGTTCCCACTTTGACTTCATTGTAAGGTACTTCTTTGCG GCGCTGACAGTGCTCACGCTCCTGGGCCTCCTCCATGGACTCGTGCTGCTGCCTGTGCTGCTGTCCATCCTGGGCCCGCCGCCAGAGGTG >In-frame_C1orf213_ENST00000335648_chr1_23696006_+_PTCH2_ENST00000372192_chr1_45292440_-_3402nt ATGTTAGCAGTCCCTGTCCGGTTGAAGGTAGGAAGCCGAAAACCCGAGTGGGGGACGAACAGACTTACCTCCTGTCCCGCAAAAGATCCA CTAGATCGTCGTCTCCAAAACCTGAGAGACCGCGAACGGGTTCCAGAGCCGCAGCGTTCTCTCAGACCTGGCGTTCAGGAAGATTCTAGA GAGCACGGGCAGGTCCCGGAGGTCTCAGACCCGCAGGTAGATCTCGAATTCGTAGACTTGCAGGCGAAGCCCAGATATCGTAGGCTGATC CTAAAGACTCAGATTCCCGAGGCCTCAGACTCGCAGGCAGCTCAGAAACCACAGGCTCATAGGCAGATCCCTGAGACCACAGAGGCTGGC CGAGAAACCACCAGCAACTAAGCTGCATTCAGCTGGAGTTCCTCGGAACGGGAGGACTCGCAGCTCTCCCTTTCCCCAGCCAGGATGAGG GAATTAGACAATGGAAGTCGAGCACTGGGGAAAGCAGGCATTCTGCGTGGGGAAGAGCTCCCAGCTCGCTGTAGCCTTGGAGAGGGAAGT GATGGAAAAAGAATATAGCAGCTTATTAGGGACTCCCACCCTCTTCAAGTTATAAATATCCCCAGAACCTTGGCTACGTGCCCGGAAGCC TGTTGTCTCTAACTGTACAGGAGACTTCTCTGCCTGGGCTGGGAAAGGGGCCTTTCTTTTGTTTTGCAGATAGATCCACCCACTGAGGAA CTTGAAAATTTTTTTCAAACATAACTCCAGGCCTTGCTTTTATTAGTGAGTGTCCTGTTCCCAGTGCCCGGTTATTTATGATTAAATTAC TGAAGTGTCTAAAAAGAACAGAAGGACCCACCCCAGCCATAATGCAGACTTTCCCATTCCTTCTCTTTCCACCCGCAACTGTGGGGCTAA GAATTCTTAAGATGTCACAGAATTATACCATCCTACCTCATCTAAAGTCGATCCGAGGCTGGTCCGATGGTAGTGGGTTACCAGAACTTA ATAACATTAATAACTCTAAAGTTAGTATACAACCCCCCACTGCTAAATTTGGCTATAAAAATAAAATTGATCTGAGCACCATATAAAATG GAATCCTGGAGGGTCCCCTAGAGGCAGTATCCCCAGTGGAAAGAGCGTGGGCCTCAAGGTCAGACAAGCCTGGTTTGGAATCCAGGCTGT GTATCCTTTGGAAAGTCATTGAATCCAGGCCCATTTCCTTTTCTCTAAAATGAGGGTCATCATACCTAAGGATGTTGTGAGGCGTGAGTG AGATGATTAAAGCGTTCCAGAGAGTGCGCTCTTGGATGATAGCCGTTACTTTTTATTAACCCTGGCTTTGGTGGTAAGGGAAACTTCCAG AAATGCTTGTGGGTATATTGGATAGCTCAGAAAATCTGGGAAATCAAAGTGGCTCAATAGCTGTGAGGAACTGTGGGTGACTTTATCCTC ACATCGTGTTTCTTCCAGAAATTCAGACGCAACAGAGGTTAGGCCAGTTTGGTGGGTTCCAGTGAGCGGTGTGTTGAGCCTAGTAGAGCA TAGGTACTTGGGGTTGCCAAAACCCCAGCAAGTTGAGGCTTCACGCTCAGGGAAACTTCTGGGTCAGAGGTTAATAACCACGCTCCTTGG AGCAAGGAGGAGGGGAGCCTTTCTGACTAGCTGAAGTAATTGCAGGTTTCTAACTGGGCCTAAGGTGAGCTGAGGGCTTGAGCCCCTCAG CCCAGCGGGGGTCCCTTTTCATCCCTTCTCTGACAGATTGCTTTGTAAACTTTCTTAGGCCTTCCCCCCACCCCTTTGCCCCAGTGCTTT AAGCCCTTCTTTGTCTTCTTGCTGTTTCTTTTATTCCTCAGGCCTGCGGGGCGGGGGCGGGGTGGCGCCCAGGACGACTCCCCGGGCTCA GCTTGGCTGCCTGCCTCCTTCTGTAAGTGCTTTTTTTTTCTTCACCTGGGACCCTCTAGAGGTTGGAAAGAGAAGAGAGGCTGGGAGCGG ATGGAAAGCATGACTGCATCTGGAGCCCCTGGGGGGAGTGGGGAAGAGGGAGTGGAAGGACAGTGGCTGAGGGGCTTCCTGTTGCAGCCT TCAGCTGGACTCAGGGTTGGGGTCACTGGAGGAGGAGGTGGCTTCCTGCCCCATTGTTCTGGACTGCAGTGTTTCTTGGGAATACTTACT GTATGTGGATTTTCAGTAACCAACTTGGAAAGCTGTATTTGTTCCCATGATTCAGCAAACAATGAGTACCTACTGTGTGTAGAAGCAGCA GGACAGCCTGTCATCACTGGGAAAGAGGCCAGAAGAGCCGTTTGGCCAGGGTCTCCAATTTAGGCTTTCAACATTATCTCTAAAGAAGGT TATACATTATGTCGGCTCCACTGGCTGATGGGATCAAAGACCCTCCTTGTATATCCTTAAACCTGTACTCTATTACCAGGCCACTGTGCC TGTGGAGCACTGTAAGTTCCTACCTTTTAATAAATTTTATAATTATCTTGTGAGCTCCCGCCAGCTCAGCCCTTGGAGTTTGCCCAGTTC CCCTTCCTGCTGCGTGGCCTCCAGAAGACTGCAGACTTTGTGGAGGCCATCGAGGGGGCCCGGGCAGCATGCGCAGAGGCCGGCCAGGCT GGGGTGCACGCCTACCCCAGCGGCTCCCCCTTCCTCTTCTGGGAACAGTATCTGGGCCTGCGGCGCTGCTTCCTGCTGGCCGTCTGCATC CTGCTGGTGTGCACTTTCCTCGTCTGTGCTCTGCTGCTCCTCAACCCCTGGACGGCTGGCCTCATAGTGCTGGTCCTGGCGATGATGACA GTGGAACTCTTTGGTATCATGGGTTTCCTGGGCATCAAGCTGAGTGCCATCCCCGTGGTGATCCTTGTGGCCTCTGTAGGCATTGGCGTT GAGTTCACAGTCCACGTGGCTCTGGGCTTCCTGACCACCCAGGGCAGCCGGAACCTGCGGGCCGCCCATGCCCTTGAGCACACATTTGCC CCCGTGACCGATGGGGCCATCTCCACATTGCTGGGTCTGCTCATGCTTGCTGGTTCCCACTTTGACTTCATTGTAAGGTACTTCTTTGCG GCGCTGACAGTGCTCACGCTCCTGGGCCTCCTCCATGGACTCGTGCTGCTGCCTGTGCTGCTGTCCATCCTGGGCCCGCCGCCAGAGGTG ATACAGATGTACAAGGAAAGCCCAGAGATCCTGAGTCCACCAGCTCCACAGGGAGGCGGGCTTAGGTGGGGGGCATCCTCCTCCCTGCCC CAGAGCTTTGCCAGAGTGACTACCTCCATGACCGTGGCCATCCACCCACCCCCCCTGCCTGGTGCCTACATCCATCCAGCCCCTGATGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_C1orf213_ENST00000335648_chr1_23696006_+_PTCH2_ENST00000447098_chr1_45292440_-_3860nt GTAGATCTCGAATTCGTAGACTTGCAGGCGAAGCCCAGATATCGTAGGCTGATCCTAAAGACTCAGATTCCCGAGGCCTCAGACTCGCAG GCAGCTCAGAAACCACAGGCTCATAGGCAGATCCCTGAGACCACAGAGGCTGGCCGAGAAACCACCAGCAACTAAGCTGCATTCAGCTGG AGTTCCTCGGAACGGGAGGACTCGCAGCTCTCCCTTTCCCCAGCCAGGATGAGGGAATTAGACAATGGAAGTCGAGCACTGGGGAAAGCA GGCATTCTGCGTGGGGAAGAGCTCCCAGCTCGCTGTAGCCTTGGAGAGGGAAGTGATGGAAAAAGAATATAGCAGCTTATTAGGGACTCC CACCCTCTTCAAGTTATAAATATCCCCAGAACCTTGGCTACGTGCCCGGAAGCCTGTTGTCTCTAACTGTACAGGAGACTTCTCTGCCTG GGCTGGGAAAGGGGCCTTTCTTTTGTTTTGCAGATAGATCCACCCACTGAGGAACTTGAAAATTTTTTTCAAACATAACTCCAGGCCTTG CTTTTATTAGTGAGTGTCCTGTTCCCAGTGCCCGGTTATTTATGATTAAATTACTGAAGTGTCTAAAAAGAACAGAAGGACCCACCCCAG CCATAATGCAGACTTTCCCATTCCTTCTCTTTCCACCCGCAACTGTGGGGCTAAGAATTCTTAAGATGTCACAGAATTATACCATCCTAC CTCATCTAAAGTCGATCCGAGGCTGGTCCGATGGTAGTGGGTTACCAGAACTTAATAACATTAATAACTCTAAAGTTAGTATACAACCCC CCACTGCTAAATTTGGCTATAAAAATAAAATTGATCTGAGCACCATATAAAATGGAATCCTGGAGGGTCCCCTAGAGGCAGTATCCCCAG TGGAAAGAGCGTGGGCCTCAAGGTCAGACAAGCCTGGTTTGGAATCCAGGCTGTGTATCCTTTGGAAAGTCATTGAATCCAGGCCCATTT CCTTTTCTCTAAAATGAGGGTCATCATACCTAAGGATGTTGTGAGGCGTGAGTGAGATGATTAAAGCGTTCCAGAGAGTGCGCTCTTGGA TGATAGCCGTTACTTTTTATTAACCCTGGCTTTGGTGGTAAGGGAAACTTCCAGAAATGCTTGTGGGTATATTGGATAGCTCAGAAAATC TGGGAAATCAAAGTGGCTCAATAGCTGTGAGGAACTGTGGGTGACTTTATCCTCACATCGTGTTTCTTCCAGAAATTCAGACGCAACAGA GGTTAGGCCAGTTTGGTGGGTTCCAGTGAGCGGTGTGTTGAGCCTAGTAGAGCATAGGTACTTGGGGTTGCCAAAACCCCAGCAAGTTGA GGCTTCACGCTCAGGGAAACTTCTGGGTCAGAGGTTAATAACCACGCTCCTTGGAGCAAGGAGGAGGGGAGCCTTTCTGACTAGCTGAAG TAATTGCAGGTTTCTAACTGGGCCTAAGGTGAGCTGAGGGCTTGAGCCCCTCAGCCCAGCGGGGGTCCCTTTTCATCCCTTCTCTGACAG ATTGCTTTGTAAACTTTCTTAGGCCTTCCCCCCACCCCTTTGCCCCAGTGCTTTAAGCCCTTCTTTGTCTTCTTGCTGTTTCTTTTATTC CTCAGGCCTGCGGGGCGGGGGCGGGGTGGCGCCCAGGACGACTCCCCGGGCTCAGCTTGGCTGCCTGCCTCCTTCTGTAAGTGCTTTTTT TTTCTTCACCTGGGACCCTCTAGAGGTTGGAAAGAGAAGAGAGGCTGGGAGCGGATGGAAAGCATGACTGCATCTGGAGCCCCTGGGGGG AGTGGGGAAGAGGGAGTGGAAGGACAGTGGCTGAGGGGCTTCCTGTTGCAGCCTTCAGCTGGACTCAGGGTTGGGGTCACTGGAGGAGGA GGTGGCTTCCTGCCCCATTGTTCTGGACTGCAGTGTTTCTTGGGAATACTTACTGTATGTGGATTTTCAGTAACCAACTTGGAAAGCTGT ATTTGTTCCCATGATTCAGCAAACAATGAGTACCTACTGTGTGTAGAAGCAGCAGGACAGCCTGTCATCACTGGGAAAGAGGCCAGAAGA GCCGTTTGGCCAGGGTCTCCAATTTAGGCTTTCAACATTATCTCTAAAGAAGGTTATACATTATGTCGGCTCCACTGGCTGATGGGATCA AAGACCCTCCTTGTATATCCTTAAACCTGTACTCTATTACCAGGCCACTGTGCCTGTGGAGCACTGTAAGTTCCTACCTTTTAATAAATT TTATAATTATCTTGTGAGCTCCCGCCAGCTCAGCCCTTGGAGTTTGCCCAGTTCCCCTTCCTGCTGCGTGGCCTCCAGAAGACTGCAGAC TTTGTGGAGGCCATCGAGGGGGCCCGGGCAGCATGCGCAGAGGCCGGCCAGGCTGGGGTGCACGCCTACCCCAGCGGCTCCCCCTTCCTC TTCTGGGAACAGTATCTGGGCCTGCGGCGCTGCTTCCTGCTGGCCGTCTGCATCCTGCTGGTGTGCACTTTCCTCGTCTGTGCTCTGCTG CTCCTCAACCCCTGGACGGCTGGCCTCATAGTGCTGGTCCTGGCGATGATGACAGTGGAACTCTTTGGTATCATGGGTTTCCTGGGCATC AAGCTGAGTGCCATCCCCGTGGTGATCCTTGTGGCCTCTGTAGGCATTGGCGTTGAGTTCACAGTCCACGTGGCTCTGGGCTTCCTGACC ACCCAGGGCAGCCGGAACCTGCGGGCCGCCCATGCCCTTGAGCACACATTTGCCCCCGTGACCGATGGGGCCATCTCCACATTGCTGGGT CTGCTCATGCTTGCTGGTTCCCACTTTGACTTCATTGTAAGGTACTTCTTTGCGGCGCTGACAGTGCTCACGCTCCTGGGCCTCCTCCAT GGACTCGTGCTGCTGCCTGTGCTGCTGTCCATCCTGGGCCCGCCGCCAGAGGTGATACAGATGTACAAGGAAAGCCCAGAGATCCTGAGT CCACCAGCTCCACAGGGAGGCGGGCTTAGGCCCGAGGAGATCTAGCCTCTGCCTCCCACCCCAGCACCCCCTCATCAGACACACGGAGCG CCACTGTCTGGACAGGCTGAATTGGTCTTCGGGTCCCTAATTTCTCATACGCCATTCCCTCTGCCTAGAACACTTTCTCACCTCCCCTTG ATGTGACCCCATATCACCCTTCGAGGTGAATTGGATCGGATGCCATCTCCTCCAGGAGGGGTGGGGTCGTGCCTCCTGTGAGGTCCCAGT GCCCCTGAGTGTCTGTGCCCGTCTGTTTCCCCGTCCCTCTCTCTAAGCCCGGAGGCTTACTGCGGGTAAGGACGGCGGGACAGGACCTTA ACCCCTGGGACGAACACCAGCTCCGCAAAGGACTCCGCACCCGGCGCCGCCCACGGGGTGCGGGTCCCAGGAGGACCAGCAGAGAGGAGC ATAGGAGAGCAAAGGAGATCAGTGACCCATGGCTTCCCCGGTGGCGCGGAACAGCCCGGAGCCGCCTGTGATTTGCATACCCATGGTGCA CCACGAAAAGATACCCTCAAGATGCTTGCACTCCCTCTGTGCGCGCATTTCTGCACTGTTTTAGAGCATGATGCCTCTTACACGCATCTG TGTGCATAAACTACATATAGGGAGTGCGTACCACGCAGGCATCCAACAACCATAAGTGTGTTAAGTGTTAGTTCTCCCTGCGAGGTTCGA AGCGGAAGTCACGAATATACTCGGGTTTCTCTTCAAAGCGCATAAATCTTTCGCCTTTTACTAAAGATTTCCGTGGAGAGAAAGTTGTGA >In-frame_C1orf213_ENST00000335648_chr1_23696006_+_PTCH2_ENST00000372192_chr1_45292440_-_3668nt GTAGATCTCGAATTCGTAGACTTGCAGGCGAAGCCCAGATATCGTAGGCTGATCCTAAAGACTCAGATTCCCGAGGCCTCAGACTCGCAG GCAGCTCAGAAACCACAGGCTCATAGGCAGATCCCTGAGACCACAGAGGCTGGCCGAGAAACCACCAGCAACTAAGCTGCATTCAGCTGG AGTTCCTCGGAACGGGAGGACTCGCAGCTCTCCCTTTCCCCAGCCAGGATGAGGGAATTAGACAATGGAAGTCGAGCACTGGGGAAAGCA GGCATTCTGCGTGGGGAAGAGCTCCCAGCTCGCTGTAGCCTTGGAGAGGGAAGTGATGGAAAAAGAATATAGCAGCTTATTAGGGACTCC CACCCTCTTCAAGTTATAAATATCCCCAGAACCTTGGCTACGTGCCCGGAAGCCTGTTGTCTCTAACTGTACAGGAGACTTCTCTGCCTG GGCTGGGAAAGGGGCCTTTCTTTTGTTTTGCAGATAGATCCACCCACTGAGGAACTTGAAAATTTTTTTCAAACATAACTCCAGGCCTTG CTTTTATTAGTGAGTGTCCTGTTCCCAGTGCCCGGTTATTTATGATTAAATTACTGAAGTGTCTAAAAAGAACAGAAGGACCCACCCCAG CCATAATGCAGACTTTCCCATTCCTTCTCTTTCCACCCGCAACTGTGGGGCTAAGAATTCTTAAGATGTCACAGAATTATACCATCCTAC CTCATCTAAAGTCGATCCGAGGCTGGTCCGATGGTAGTGGGTTACCAGAACTTAATAACATTAATAACTCTAAAGTTAGTATACAACCCC CCACTGCTAAATTTGGCTATAAAAATAAAATTGATCTGAGCACCATATAAAATGGAATCCTGGAGGGTCCCCTAGAGGCAGTATCCCCAG TGGAAAGAGCGTGGGCCTCAAGGTCAGACAAGCCTGGTTTGGAATCCAGGCTGTGTATCCTTTGGAAAGTCATTGAATCCAGGCCCATTT CCTTTTCTCTAAAATGAGGGTCATCATACCTAAGGATGTTGTGAGGCGTGAGTGAGATGATTAAAGCGTTCCAGAGAGTGCGCTCTTGGA TGATAGCCGTTACTTTTTATTAACCCTGGCTTTGGTGGTAAGGGAAACTTCCAGAAATGCTTGTGGGTATATTGGATAGCTCAGAAAATC TGGGAAATCAAAGTGGCTCAATAGCTGTGAGGAACTGTGGGTGACTTTATCCTCACATCGTGTTTCTTCCAGAAATTCAGACGCAACAGA GGTTAGGCCAGTTTGGTGGGTTCCAGTGAGCGGTGTGTTGAGCCTAGTAGAGCATAGGTACTTGGGGTTGCCAAAACCCCAGCAAGTTGA GGCTTCACGCTCAGGGAAACTTCTGGGTCAGAGGTTAATAACCACGCTCCTTGGAGCAAGGAGGAGGGGAGCCTTTCTGACTAGCTGAAG TAATTGCAGGTTTCTAACTGGGCCTAAGGTGAGCTGAGGGCTTGAGCCCCTCAGCCCAGCGGGGGTCCCTTTTCATCCCTTCTCTGACAG ATTGCTTTGTAAACTTTCTTAGGCCTTCCCCCCACCCCTTTGCCCCAGTGCTTTAAGCCCTTCTTTGTCTTCTTGCTGTTTCTTTTATTC CTCAGGCCTGCGGGGCGGGGGCGGGGTGGCGCCCAGGACGACTCCCCGGGCTCAGCTTGGCTGCCTGCCTCCTTCTGTAAGTGCTTTTTT TTTCTTCACCTGGGACCCTCTAGAGGTTGGAAAGAGAAGAGAGGCTGGGAGCGGATGGAAAGCATGACTGCATCTGGAGCCCCTGGGGGG AGTGGGGAAGAGGGAGTGGAAGGACAGTGGCTGAGGGGCTTCCTGTTGCAGCCTTCAGCTGGACTCAGGGTTGGGGTCACTGGAGGAGGA GGTGGCTTCCTGCCCCATTGTTCTGGACTGCAGTGTTTCTTGGGAATACTTACTGTATGTGGATTTTCAGTAACCAACTTGGAAAGCTGT ATTTGTTCCCATGATTCAGCAAACAATGAGTACCTACTGTGTGTAGAAGCAGCAGGACAGCCTGTCATCACTGGGAAAGAGGCCAGAAGA GCCGTTTGGCCAGGGTCTCCAATTTAGGCTTTCAACATTATCTCTAAAGAAGGTTATACATTATGTCGGCTCCACTGGCTGATGGGATCA AAGACCCTCCTTGTATATCCTTAAACCTGTACTCTATTACCAGGCCACTGTGCCTGTGGAGCACTGTAAGTTCCTACCTTTTAATAAATT TTATAATTATCTTGTGAGCTCCCGCCAGCTCAGCCCTTGGAGTTTGCCCAGTTCCCCTTCCTGCTGCGTGGCCTCCAGAAGACTGCAGAC TTTGTGGAGGCCATCGAGGGGGCCCGGGCAGCATGCGCAGAGGCCGGCCAGGCTGGGGTGCACGCCTACCCCAGCGGCTCCCCCTTCCTC TTCTGGGAACAGTATCTGGGCCTGCGGCGCTGCTTCCTGCTGGCCGTCTGCATCCTGCTGGTGTGCACTTTCCTCGTCTGTGCTCTGCTG CTCCTCAACCCCTGGACGGCTGGCCTCATAGTGCTGGTCCTGGCGATGATGACAGTGGAACTCTTTGGTATCATGGGTTTCCTGGGCATC AAGCTGAGTGCCATCCCCGTGGTGATCCTTGTGGCCTCTGTAGGCATTGGCGTTGAGTTCACAGTCCACGTGGCTCTGGGCTTCCTGACC ACCCAGGGCAGCCGGAACCTGCGGGCCGCCCATGCCCTTGAGCACACATTTGCCCCCGTGACCGATGGGGCCATCTCCACATTGCTGGGT CTGCTCATGCTTGCTGGTTCCCACTTTGACTTCATTGTAAGGTACTTCTTTGCGGCGCTGACAGTGCTCACGCTCCTGGGCCTCCTCCAT GGACTCGTGCTGCTGCCTGTGCTGCTGTCCATCCTGGGCCCGCCGCCAGAGGTGATACAGATGTACAAGGAAAGCCCAGAGATCCTGAGT CCACCAGCTCCACAGGGAGGCGGGCTTAGGTGGGGGGCATCCTCCTCCCTGCCCCAGAGCTTTGCCAGAGTGACTACCTCCATGACCGTG GCCATCCACCCACCCCCCCTGCCTGGTGCCTACATCCATCCAGCCCCTGATGAGCCCCCTTGGTCCCCTGCTGCCACTAGCTCTGGCAAC CTCAGTTCCAGGGGACCAGGTCCAGCCACTGGGTGAAAGAGCAGCTGAAGCACAGAGACCATGTGTGGGGCGTGTGGGGTCACTGGGAAG CACTGGGTCTGGTGTTAGACGCAGGATGGACCCCTGGAGGGCCCTGCTGCTGCTGCATCCCCTCTCCCGACCCAGCTGTCATGGGCCTCC CTGATATCCATACAGAACAGCCACCGATTTGCACATCCAGGCCTGTGTGAGCCTGTATCTGTGTCACTTGAGAGTGAAAGCTGGCACTTG GGGCTGCAGTGCAGCCCTGTCCCCCTTCCCACCCCACACCACTGCCTGCCCAGCTGACCAAGCCTGAGGGACCCTCCAGCACCCTTCCGT CTGGTGACTCCTGGGCAGGCTCTCCATATCCCTGCCCACCTCCTACCACATCCATTATTTATATGAAAATGTCTATTTTTGTAGTATACA |
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FusionGenePPI for C1orf213_PTCH2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| C1orf213 | PTCH2 | SMO, ARRB1, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for C1orf213_PTCH2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for C1orf213_PTCH2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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