FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 4651

FusionGeneSummary for C11orf80_PPP6R3

check button Fusion gene summary
Fusion gene informationFusion gene name: C11orf80_PPP6R3
Fusion gene ID: 4651
HgeneTgene
Gene symbol

C11orf80

PPP6R3

Gene ID

79703

55291

Gene namechromosome 11 open reading frame 80protein phosphatase 6 regulatory subunit 3
SynonymsTOP6BL|TOPOVIBLC11orf23|PP6R3|SAP190|SAPL|SAPLa|SAPS3
Cytomap

11q13.2

11q13.2

Type of geneprotein-codingprotein-coding
Descriptiontype 2 DNA topoisomerase 6 subunit B-liketype 2 DNA topoisomerase VI subunit B-likeserine/threonine-protein phosphatase 6 regulatory subunit 3SAPS domain family, member 3sporulation-induced transcript 4-associated protein SAPL
Modification date2018052320180520
UniProtAcc

Q5H9R7

Ensembl transtripts involved in fusion geneENST00000346672, ENST00000360962, 
ENST00000527634, ENST00000540737, 
ENST00000532565, ENST00000525449, 
ENST00000527368, 
ENST00000393799, 
ENST00000530427, ENST00000393800, 
ENST00000534534, ENST00000524845, 
ENST00000265637, ENST00000524904, 
ENST00000393801, ENST00000265636, 
ENST00000529710, ENST00000527403, 
Fusion gene scores* DoF score10 X 5 X 6=30015 X 15 X 6=1350
# samples 1119
** MAII scorelog2(11/300*10)=-1.44745897697122
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(19/1350*10)=-2.82888808360725
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: C11orf80 [Title/Abstract] AND PPP6R3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePPP6R3

GO:0043666

regulation of phosphoprotein phosphatase activity

16716191


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-C8-A8HQ-01AC11orf80chr11

66526567

+PPP6R3chr11

68286969

+
TCGALDLUSCTCGA-85-8582-01AC11orf80chr11

66512390

+PPP6R3chr11

68286969

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000346672ENST00000393799C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-3UTRENST00000346672ENST00000530427C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000393800C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000534534C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000524845C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-intronENST00000346672ENST00000265637C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000524904C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000393801C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000265636C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000529710C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000346672ENST00000527403C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000393799C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-3UTRENST00000360962ENST00000530427C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000393800C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000534534C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000524845C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-intronENST00000360962ENST00000265637C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000524904C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000393801C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000265636C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000529710C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000527403C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000393799C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-3UTRENST00000527634ENST00000530427C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000393800C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000534534C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000524845C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-intronENST00000527634ENST00000265637C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000524904C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000393801C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000265636C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000529710C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000527403C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000393799C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-3UTRENST00000540737ENST00000530427C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000393800C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000534534C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000524845C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-intronENST00000540737ENST00000265637C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000524904C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000393801C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000265636C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000529710C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000540737ENST00000527403C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000393799C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-3UTRENST00000532565ENST00000530427C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000393800C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000534534C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000524845C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-intronENST00000532565ENST00000265637C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000524904C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000393801C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000265636C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000529710C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000527403C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000393799C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-3UTRENST00000525449ENST00000530427C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000393800C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000534534C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000524845C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-intronENST00000525449ENST00000265637C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000524904C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000393801C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000265636C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000529710C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000525449ENST00000527403C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000393799C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-3UTRENST00000527368ENST00000530427C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000393800C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000534534C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000524845C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-intronENST00000527368ENST00000265637C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000524904C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000393801C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000265636C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000529710C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000527403C11orf80chr11

66526567

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000393799C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-3UTRENST00000346672ENST00000530427C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000393800C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000534534C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000524845C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-intronENST00000346672ENST00000265637C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000524904C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000393801C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000265636C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000529710C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000346672ENST00000527403C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000393799C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-3UTRENST00000360962ENST00000530427C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000393800C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000534534C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000524845C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-intronENST00000360962ENST00000265637C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000524904C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000393801C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000265636C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000529710C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5CDS-5UTRENST00000360962ENST00000527403C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000393799C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-3UTRENST00000527634ENST00000530427C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000393800C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000534534C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000524845C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-intronENST00000527634ENST00000265637C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000524904C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000393801C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000265636C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000529710C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000527634ENST00000527403C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000393799C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-3UTRENST00000540737ENST00000530427C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000393800C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000534534C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000524845C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-intronENST00000540737ENST00000265637C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000524904C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000393801C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000265636C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000529710C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000540737ENST00000527403C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000393799C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-3UTRENST00000532565ENST00000530427C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000393800C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000534534C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000524845C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-intronENST00000532565ENST00000265637C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000524904C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000393801C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000265636C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000529710C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
5UTR-5UTRENST00000532565ENST00000527403C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000393799C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-3UTRENST00000525449ENST00000530427C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000393800C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000534534C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000524845C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-intronENST00000525449ENST00000265637C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000524904C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000393801C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000265636C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000529710C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
intron-5UTRENST00000525449ENST00000527403C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000393799C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-3UTRENST00000527368ENST00000530427C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000393800C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000534534C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000524845C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-intronENST00000527368ENST00000265637C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000524904C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000393801C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000265636C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000529710C11orf80chr11

66512390

+PPP6R3chr11

68286969

+
3UTR-5UTRENST00000527368ENST00000527403C11orf80chr11

66512390

+PPP6R3chr11

68286969

+

Top

FusionProtFeatures for C11orf80_PPP6R3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
C11orf80

PPP6R3

Q5H9R7

Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for C11orf80_PPP6R3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for C11orf80_PPP6R3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
C11orf80PPP6R3KDM6A, TNFAIP3, USP21, USP36, USP49, PPP6C, PRKDC, HDAC1, HDAC2, ELAVL1, SIRT7, TERF2IP, TINF2, TFAP4, GRK5, PFAS, BRCA1, ECT2, NOTCH1, LATS1, GPSM1, HDAC11, USP10, ANKRD28, MOB1A, MOB1B, ACAD11, ANKRD44, ANKRD52, AP1B1, AP2A1, AP2A2, AURKA, DNAJC11, ECH1, ERLIN2, PPP6R1, PPP6R2, CDC37, ENAH, ETFA, HSP90AA1, HSP90AB1, RUVBL2, SRRT, TPM1, USP7, CSNK1E, SNAI2, RNF2, GPHA2, RPS6KB2, UNK, DIEXF, NSUN5, EIF4A3, TIPRL, NTRK1, CEP44, CEP19, XPO1, ZNRF2, ZNF746, TRMT2A, TRIM25, TES


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for C11orf80_PPP6R3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for C11orf80_PPP6R3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource