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Fusion gene ID: 46 |
FusionGeneSummary for AARSD1_FBXL20 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AARSD1_FBXL20 | Fusion gene ID: 46 | Hgene | Tgene | Gene symbol | AARSD1 | FBXL20 | Gene ID | 80755 | 84961 |
| Gene name | alanyl-tRNA synthetase domain containing 1 | F-box and leucine rich repeat protein 20 | |
| Synonyms | - | Fbl2|Fbl20 | |
| Cytomap | 17q21.31 | 17q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | alanyl-tRNA editing protein Aarsd1alanyl-tRNA synthetase domain-containing protein 1 | F-box/LRR-repeat protein 20F-box protein FBL2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9BTE6 | Q96IG2 | |
| Ensembl transtripts involved in fusion gene | ENST00000427569, ENST00000416949, | ENST00000583610, ENST00000394294, ENST00000264658, ENST00000577399, | |
| Fusion gene scores | * DoF score | 5 X 5 X 5=125 | 11 X 7 X 6=462 |
| # samples | 5 | 14 | |
| ** MAII score | log2(5/125*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(14/462*10)=-1.72246602447109 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: AARSD1 [Title/Abstract] AND FBXL20 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-BT-A2LA-01A | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000427569 | ENST00000583610 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| In-frame | ENST00000427569 | ENST00000394294 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| In-frame | ENST00000427569 | ENST00000264658 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| In-frame | ENST00000427569 | ENST00000577399 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| intron-3CDS | ENST00000416949 | ENST00000583610 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| intron-3CDS | ENST00000416949 | ENST00000394294 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| intron-3CDS | ENST00000416949 | ENST00000264658 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
| intron-3CDS | ENST00000416949 | ENST00000577399 | AARSD1 | chr17 | 41108221 | - | FBXL20 | chr17 | 37499494 | - |
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FusionProtFeatures for AARSD1_FBXL20 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AARSD1 | FBXL20 |
| Functions in trans to edit the amino acid moiety fromincorrectly charged tRNA(Ala). {ECO:0000250}. | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neuraltransmission (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 22_68 | 14 | 437 | Domain | F-box |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 22_68 | 14 | 405 | Domain | F-box |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 22_68 | 14 | 411 | Domain | F-box |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 101_126 | 14 | 437 | Repeat | Note=LRR 2 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 127_152 | 14 | 437 | Repeat | Note=LRR 3 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 153_178 | 14 | 437 | Repeat | Note=LRR 4 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 179_204 | 14 | 437 | Repeat | Note=LRR 5 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 205_230 | 14 | 437 | Repeat | Note=LRR 6 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 231_256 | 14 | 437 | Repeat | Note=LRR 7 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 257_282 | 14 | 437 | Repeat | Note=LRR 8 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 283_308 | 14 | 437 | Repeat | Note=LRR 9 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 309_334 | 14 | 437 | Repeat | Note=LRR 10 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 335_363 | 14 | 437 | Repeat | Note=LRR 11 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 364_388 | 14 | 437 | Repeat | Note=LRR 12 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 389_414 | 14 | 437 | Repeat | Note=LRR 13 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000264658 | - | 0 | 15 | 74_100 | 14 | 437 | Repeat | Note=LRR 1 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 101_126 | 14 | 405 | Repeat | Note=LRR 2 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 127_152 | 14 | 405 | Repeat | Note=LRR 3 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 153_178 | 14 | 405 | Repeat | Note=LRR 4 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 179_204 | 14 | 405 | Repeat | Note=LRR 5 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 205_230 | 14 | 405 | Repeat | Note=LRR 6 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 231_256 | 14 | 405 | Repeat | Note=LRR 7 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 257_282 | 14 | 405 | Repeat | Note=LRR 8 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 283_308 | 14 | 405 | Repeat | Note=LRR 9 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 309_334 | 14 | 405 | Repeat | Note=LRR 10 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 335_363 | 14 | 405 | Repeat | Note=LRR 11 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 364_388 | 14 | 405 | Repeat | Note=LRR 12 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 389_414 | 14 | 405 | Repeat | Note=LRR 13 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000394294 | - | 0 | 14 | 74_100 | 14 | 405 | Repeat | Note=LRR 1 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 101_126 | 14 | 411 | Repeat | Note=LRR 2 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 127_152 | 14 | 411 | Repeat | Note=LRR 3 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 153_178 | 14 | 411 | Repeat | Note=LRR 4 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 179_204 | 14 | 411 | Repeat | Note=LRR 5 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 205_230 | 14 | 411 | Repeat | Note=LRR 6 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 231_256 | 14 | 411 | Repeat | Note=LRR 7 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 257_282 | 14 | 411 | Repeat | Note=LRR 8 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 283_308 | 14 | 411 | Repeat | Note=LRR 9 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 309_334 | 14 | 411 | Repeat | Note=LRR 10 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 335_363 | 14 | 411 | Repeat | Note=LRR 11 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 364_388 | 14 | 411 | Repeat | Note=LRR 12 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 389_414 | 14 | 411 | Repeat | Note=LRR 13 |
| Tgene | >FBXL20 | chr17:41108221 | chr17:37499494 | ENST00000583610 | - | 0 | 16 | 74_100 | 14 | 411 | Repeat | Note=LRR 1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for AARSD1_FBXL20 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000583610_chr17_37499494_-_221aa MAFWCQRDSYAREFTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDDRGTINDISVLRVTRRGEQADHFTQTPLDPG SQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIELDTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEV >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000394294_chr17_37499494_-_612aa MAFWCQRDSYAREFTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDDRGTINDISVLRVTRRGEQADHFTQTPLDPG SQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIELDTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEV EQVSGRGLPDDHAGPIRVVNIEGVDSNMCCGTHVSNLSDLQMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGS NWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDAEGCPLLEQLNISWCDQVTKD GIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRL RILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCP >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000264658_chr17_37499494_-_644aa MAFWCQRDSYAREFTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDDRGTINDISVLRVTRRGEQADHFTQTPLDPG SQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIELDTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEV EQVSGRGLPDDHAGPIRVVNIEGVDSNMCCGTHVSNLSDLQMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGS NWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASC TSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITIC RGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLS HCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVG >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000577399_chr17_37499494_-_644aa MAFWCQRDSYAREFTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDDRGTINDISVLRVTRRGEQADHFTQTPLDPG SQVLVRVDWERRFDHMQQHSGQHLITAVADHLFKLKTTSWELGRFRSAIELDTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLDDPEV EQVSGRGLPDDHAGPIRVVNIEGVDSNMCCGTHVSNLSDLQMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGS NWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASC TSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITIC RGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLS HCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000583610_chr17_37499494_-_663nt ATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTGGTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGG AGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACAGTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGAC CGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAGGCTGATCATTTCACCCAGACACCCCTGGATCCAGGA AGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAGCATTCAGGGCAGCATCTCATCACGGCAGTTGCTGAC CATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCGATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAA GTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTGAATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTG GAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTTGTTAACATCGAGGGCGTTGATTCCAACATGTGCTGT >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000394294_chr17_37499494_-_1836nt ATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTGGTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGG AGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACAGTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGAC CGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAGGCTGATCATTTCACCCAGACACCCCTGGATCCAGGA AGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAGCATTCAGGGCAGCATCTCATCACGGCAGTTGCTGAC CATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCGATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAA GTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTGAATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTG GAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTTGTTAACATCGAGGGCGTTGATTCCAACATGTGCTGT GGGACCCATGTGAGCAATCTCAGTGACCTTCAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTG TTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGT AACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGGCCGAGTAGTGGAGAATATTTCAAAACGATGTGGGGGCTTTTTA CGAAAGTTAAGTCTTCGTGGATGTCTTGGAGTGGGAGACAATGCATTAAGAACCTTTGCACAAAACTGCAGGAACATTGAAGTACTGAAT CTAAATGGGTGTACAAAGACAACAGACGCTGAGGGATGTCCACTGTTGGAGCAGTTGAACATTTCCTGGTGTGACCAAGTAACCAAGGAT GGCATTCAAGCACTAGTGAGGGGCTGTGGGGGTCTCAAGGCCTTATTCTTAAAAGGCTGCACGCAGCTAGAAGATGAAGCTCTCAAGTAC ATAGGTGCACACTGCCCTGAACTGGTGACTTTGAACTTGCAGACTTGCTTGCAAATCACAGATGAAGGTCTCATTACTATATGCAGAGGG TGCCATAAGTTACAATCCCTTTGTGCCTCTGGCTGCTCCAACATCACAGATGCCATCCTGAATGCTCTAGGTCAGAACTGCCCACGGCTT AGAATATTGGAAGTGGCAAGATGTTCTCAATTAACAGATGTGGGCTTTACCACTCTAGCCAGGAATTGCCATGAACTTGAAAAGATGGAC CTGGAAGAGTGTGTTCAGATAACAGATAGCACATTAATCCAACTTTCTATACACTGTCCTCGACTTCAAGTATTGAGTCTGTCTCACTGT GAGCTGATCACAGATGATGGAATTCGTCACCTGGGGAATGGGGCCTGCGCCCATGACCAGCTGGAGGTGATTGAGCTGGACAACTGCCCA CTAATCACAGATGCATCCCTGGAGCACTTGAAGAGCTGTCATAGCCTTGAGCGGATAGAACTCTATGACTGCCAGCAAATCACACGGGCT GGAATCAAGAGACTCAGGACCCATTTACCCAATATTAAAGTCCACGCCTACTTCGCACCTGTCACTCCACCCCCATCAGTAGGGGGCAGC >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000264658_chr17_37499494_-_1932nt ATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTGGTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGG AGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACAGTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGAC CGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAGGCTGATCATTTCACCCAGACACCCCTGGATCCAGGA AGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAGCATTCAGGGCAGCATCTCATCACGGCAGTTGCTGAC CATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCGATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAA GTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTGAATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTG GAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTTGTTAACATCGAGGGCGTTGATTCCAACATGTGCTGT GGGACCCATGTGAGCAATCTCAGTGACCTTCAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTG TTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGT AACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGGCCGAGTAGTGGAGAATATTTCAAAACGATGTGGGGGCTTTTTA CGAAAGTTAAGTCTTCGTGGATGTCTTGGAGTGGGAGACAATGCATTAAGAACCTTTGCACAAAACTGCAGGAACATTGAAGTACTGAAT CTAAATGGGTGTACAAAGACAACAGACGCTACATGTACTAGCCTTAGCAAGTTCTGTTCCAAACTCAGGCACCTTGACTTGGCTTCCTGT ACATCAATAACAAACATGTCTCTAAAAGCTCTGAGTGAGGGATGTCCACTGTTGGAGCAGTTGAACATTTCCTGGTGTGACCAAGTAACC AAGGATGGCATTCAAGCACTAGTGAGGGGCTGTGGGGGTCTCAAGGCCTTATTCTTAAAAGGCTGCACGCAGCTAGAAGATGAAGCTCTC AAGTACATAGGTGCACACTGCCCTGAACTGGTGACTTTGAACTTGCAGACTTGCTTGCAAATCACAGATGAAGGTCTCATTACTATATGC AGAGGGTGCCATAAGTTACAATCCCTTTGTGCCTCTGGCTGCTCCAACATCACAGATGCCATCCTGAATGCTCTAGGTCAGAACTGCCCA CGGCTTAGAATATTGGAAGTGGCAAGATGTTCTCAATTAACAGATGTGGGCTTTACCACTCTAGCCAGGAATTGCCATGAACTTGAAAAG ATGGACCTGGAAGAGTGTGTTCAGATAACAGATAGCACATTAATCCAACTTTCTATACACTGTCCTCGACTTCAAGTATTGAGTCTGTCT CACTGTGAGCTGATCACAGATGATGGAATTCGTCACCTGGGGAATGGGGCCTGCGCCCATGACCAGCTGGAGGTGATTGAGCTGGACAAC TGCCCACTAATCACAGATGCATCCCTGGAGCACTTGAAGAGCTGTCATAGCCTTGAGCGGATAGAACTCTATGACTGCCAGCAAATCACA CGGGCTGGAATCAAGAGACTCAGGACCCATTTACCCAATATTAAAGTCCACGCCTACTTCGCACCTGTCACTCCACCCCCATCAGTAGGG >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000577399_chr17_37499494_-_1932nt ATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTGGTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGG AGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACAGTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGAC CGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAGGCTGATCATTTCACCCAGACACCCCTGGATCCAGGA AGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAGCATTCAGGGCAGCATCTCATCACGGCAGTTGCTGAC CATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCGATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAA GTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTGAATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTG GAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTTGTTAACATCGAGGGCGTTGATTCCAACATGTGCTGT GGGACCCATGTGAGCAATCTCAGTGACCTTCAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTG TTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGT AACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGGCCGAGTAGTGGAGAATATTTCAAAACGATGTGGGGGCTTTTTA CGAAAGTTAAGTCTTCGTGGATGTCTTGGAGTGGGAGACAATGCATTAAGAACCTTTGCACAAAACTGCAGGAACATTGAAGTACTGAAT CTAAATGGGTGTACAAAGACAACAGACGCTACATGTACTAGCCTTAGCAAGTTCTGTTCCAAACTCAGGCACCTTGACTTGGCTTCCTGT ACATCAATAACAAACATGTCTCTAAAAGCTCTGAGTGAGGGATGTCCACTGTTGGAGCAGTTGAACATTTCCTGGTGTGACCAAGTAACC AAGGATGGCATTCAAGCACTAGTGAGGGGCTGTGGGGGTCTCAAGGCCTTATTCTTAAAAGGCTGCACGCAGCTAGAAGATGAAGCTCTC AAGTACATAGGTGCACACTGCCCTGAACTGGTGACTTTGAACTTGCAGACTTGCTTGCAAATCACAGATGAAGGTCTCATTACTATATGC AGAGGGTGCCATAAGTTACAATCCCTTTGTGCCTCTGGCTGCTCCAACATCACAGATGCCATCCTGAATGCTCTAGGTCAGAACTGCCCA CGGCTTAGAATATTGGAAGTGGCAAGATGTTCTCAATTAACAGATGTGGGCTTTACCACTCTAGCCAGGAATTGCCATGAACTTGAAAAG ATGGACCTGGAAGAGTGTGTTCAGATAACAGATAGCACATTAATCCAACTTTCTATACACTGTCCTCGACTTCAAGTATTGAGTCTGTCT CACTGTGAGCTGATCACAGATGATGGAATTCGTCACCTGGGGAATGGGGCCTGCGCCCATGACCAGCTGGAGGTGATTGAGCTGGACAAC TGCCCACTAATCACAGATGCATCCCTGGAGCACTTGAAGAGCTGTCATAGCCTTGAGCGGATAGAACTCTATGACTGCCAGCAAATCACA CGGGCTGGAATCAAGAGACTCAGGACCCATTTACCCAATATTAAAGTCCACGCCTACTTCGCACCTGTCACTCCACCCCCATCAGTAGGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000583610_chr17_37499494_-_2142nt TTCTCTGCGCGTGCGCCTCCTCACACGCCTGCAGGTATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTG GTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGGAGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACA GTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGACCGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAG GCTGATCATTTCACCCAGACACCCCTGGATCCAGGAAGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAG CATTCAGGGCAGCATCTCATCACGGCAGTTGCTGACCATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCG ATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAAGTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTG AATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTGGAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTT GTTAACATCGAGGGCGTTGATTCCAACATGTGCTGTGGGACCCATGTGAGCAATCTCAGTGACCTTCAGATGTTCTCAAATAGTGATGAA GCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTC TCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGGCCGAGTA GTGGAGAATATTTCAAAACGATGTGGGGGCTTTTTACGAAAGTTAAGTCTTCGTGGATGTCTTGGAGTGGGAGACAATGCATTAAGAACC TTTGCACAAAACTGCAGGAACATTGAAGTACTGAATCTAAATGGGTGTACAAAGACAACAGACGCTACATGTACTAGCCTTAGCAAGTTC TGTTCCAAACTCAGGCACCTTGACTTGGCTTCCTGTACATCAATAACAAACATGTCTCTAAAAGCTCTGAGTGAGGGATGTCCACTGTTG GAGCAGTTGAACATTTCCTGGTGTGACCAAGTAACCAAGGATGGCATTCAAGCACTAGTGAGGGGCTGTGGGGGTCTCAAGGCCTTATTC TTAAAAGGCTGCACGCAGCTAGAAGATGAAGCTCTCAAGTACATAGGTGCACACTGCCCTGAACTGGTGACTTTGAACTTGCAGACTTGC TTGCAAATCACAGATGAAGGTCTCATTACTATATGCAGAGGGTGCCATAAGTTACAATCCCTTTGTGCCTCTGGCTGCTCCAACATCACA GATGCCATCCTGAATGCTCTAGGTCAGAACTGCCCACGGCTTAGAATATTGGAAGTGGCAAGATGTTCTCAATTAACAGATGTGGGCTTT ACCACTCTAGCCAGGAATTGCCATGAACTTGAAAAGATGGACCTGGAAGAGTGTGTTCAGATAACAGATAGCACATTAATCCAACTTTCT ATACACTGTCCTCGACTTCAAGTATTGAGTCTGTCTCACTGTGAGCTGATCACAGATGATGGAATTCGTCACCTGGGGAATGGGGCCTGC GCCCATGACCAGCTGGAGGTGATTGAGCTGGACAACTGCCCACTAATCACAGATGCATCCCTGGAGCACTTGAAGAGCTGTCATAGCCTT GAGCGGATAGAACTCTATGACTGCCAGCAAATCACACGGGCTGGAATCAAGAGACTCAGGACCCATTTACCCAATATTAAAGTCCACGCC TACTTCGCACCTGTCACTCCACCCCCATCAGTAGGGGGCAGCAGACAGCGCTTCTGCAGATGCTGCATCATCCTATGACAATGGAGAGAT GGGGTCTCGCTATCTTGCCCAGCCTGGACTCAAACTCCTGGGCTCAAGCCTTCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGG >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000394294_chr17_37499494_-_2745nt TTCTCTGCGCGTGCGCCTCCTCACACGCCTGCAGGTATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTG GTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGGAGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACA GTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGACCGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAG GCTGATCATTTCACCCAGACACCCCTGGATCCAGGAAGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAG CATTCAGGGCAGCATCTCATCACGGCAGTTGCTGACCATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCG ATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAAGTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTG AATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTGGAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTT GTTAACATCGAGGGCGTTGATTCCAACATGTGCTGTGGGACCCATGTGAGCAATCTCAGTGACCTTCAGATGTTCTCAAATAGTGATGAA GCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTC TCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGGCCGAGTA GTGGAGAATATTTCAAAACGATGTGGGGGCTTTTTACGAAAGTTAAGTCTTCGTGGATGTCTTGGAGTGGGAGACAATGCATTAAGAACC TTTGCACAAAACTGCAGGAACATTGAAGTACTGAATCTAAATGGGTGTACAAAGACAACAGACGCTGAGGGATGTCCACTGTTGGAGCAG TTGAACATTTCCTGGTGTGACCAAGTAACCAAGGATGGCATTCAAGCACTAGTGAGGGGCTGTGGGGGTCTCAAGGCCTTATTCTTAAAA GGCTGCACGCAGCTAGAAGATGAAGCTCTCAAGTACATAGGTGCACACTGCCCTGAACTGGTGACTTTGAACTTGCAGACTTGCTTGCAA ATCACAGATGAAGGTCTCATTACTATATGCAGAGGGTGCCATAAGTTACAATCCCTTTGTGCCTCTGGCTGCTCCAACATCACAGATGCC ATCCTGAATGCTCTAGGTCAGAACTGCCCACGGCTTAGAATATTGGAAGTGGCAAGATGTTCTCAATTAACAGATGTGGGCTTTACCACT CTAGCCAGGAATTGCCATGAACTTGAAAAGATGGACCTGGAAGAGTGTGTTCAGATAACAGATAGCACATTAATCCAACTTTCTATACAC TGTCCTCGACTTCAAGTATTGAGTCTGTCTCACTGTGAGCTGATCACAGATGATGGAATTCGTCACCTGGGGAATGGGGCCTGCGCCCAT GACCAGCTGGAGGTGATTGAGCTGGACAACTGCCCACTAATCACAGATGCATCCCTGGAGCACTTGAAGAGCTGTCATAGCCTTGAGCGG ATAGAACTCTATGACTGCCAGCAAATCACACGGGCTGGAATCAAGAGACTCAGGACCCATTTACCCAATATTAAAGTCCACGCCTACTTC GCACCTGTCACTCCACCCCCATCAGTAGGGGGCAGCAGACAGCGCTTCTGCAGATGCTGCATCATCCTATGACAATGGAGGTGGTCAACC TTGGCGAACTGAGTATTTAATGACACTTCTAGAGCTACCGTGGAGTCTCTCCAGTGGAAGCAACCCCAGTGTTCTGAGCAAGGGTTACAA AGTGAGGGAGGGCAGTGTCCAGATCCCCAGAGCCACACATACATACACATACACACCCTTACCCCCATCCACTCTAGCTTTGTGACCATG GGACTGAAGTTTGTGATGGCTTTTTTATCAAGTAGATTGGTAAAATTTAACCATTCCTGTTGAGGTGCCCATAAGAAAATCATAGGCCAA GATAGGGAGGGGCATTCCAGCAAACCCCGTGTTAATGCTACTGTGGTTTTTAAATTTTTGTCTAGGGGTTTCTTTGGGGATTTTAGAACA GCATCTGCTGTCCTCCGGGGTCAAGAAAAGCATGGAAAGACAATATATGATGTACCCAGGGACCAGAAAGAAAATTTCTTTGCATCTTAG AAATGGTAGACATTCATTGTGACTAAAGAGCTTCTATGCTTCCTTGTTTCCATGCCAACATGCTGAGCATGCTCACAAAGAAGGCTCGTC CATTCCTCCTGTGTTTTAGTATTTGGCCCAGAGGTTTCCTAAATGGTTGCCTTGAAATCACTGTGGTCCAAATGTAATTCTTACACACTC AAATTATCACTGTCTGTAGCACACTTGTGCACCTGTCTTACATTCTCTGTTGCTCCCCCCCACACTCTTGCTCAGTCTGTCACCTGTTCA GTCTGCTTACTCACTCAATTGTTACCCTTTTGCTGTTGTCGTGTTTACAGTTTGCATTTTGAATGATTAGTTGGGATTACCAAACATTTT >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000264658_chr17_37499494_-_2841nt TTCTCTGCGCGTGCGCCTCCTCACACGCCTGCAGGTATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTG GTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGGAGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACA GTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGACCGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAG GCTGATCATTTCACCCAGACACCCCTGGATCCAGGAAGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAG CATTCAGGGCAGCATCTCATCACGGCAGTTGCTGACCATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCG ATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAAGTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTG AATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTGGAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTT GTTAACATCGAGGGCGTTGATTCCAACATGTGCTGTGGGACCCATGTGAGCAATCTCAGTGACCTTCAGATGTTCTCAAATAGTGATGAA GCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTC TCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGGCCGAGTA GTGGAGAATATTTCAAAACGATGTGGGGGCTTTTTACGAAAGTTAAGTCTTCGTGGATGTCTTGGAGTGGGAGACAATGCATTAAGAACC TTTGCACAAAACTGCAGGAACATTGAAGTACTGAATCTAAATGGGTGTACAAAGACAACAGACGCTACATGTACTAGCCTTAGCAAGTTC TGTTCCAAACTCAGGCACCTTGACTTGGCTTCCTGTACATCAATAACAAACATGTCTCTAAAAGCTCTGAGTGAGGGATGTCCACTGTTG GAGCAGTTGAACATTTCCTGGTGTGACCAAGTAACCAAGGATGGCATTCAAGCACTAGTGAGGGGCTGTGGGGGTCTCAAGGCCTTATTC TTAAAAGGCTGCACGCAGCTAGAAGATGAAGCTCTCAAGTACATAGGTGCACACTGCCCTGAACTGGTGACTTTGAACTTGCAGACTTGC TTGCAAATCACAGATGAAGGTCTCATTACTATATGCAGAGGGTGCCATAAGTTACAATCCCTTTGTGCCTCTGGCTGCTCCAACATCACA GATGCCATCCTGAATGCTCTAGGTCAGAACTGCCCACGGCTTAGAATATTGGAAGTGGCAAGATGTTCTCAATTAACAGATGTGGGCTTT ACCACTCTAGCCAGGAATTGCCATGAACTTGAAAAGATGGACCTGGAAGAGTGTGTTCAGATAACAGATAGCACATTAATCCAACTTTCT ATACACTGTCCTCGACTTCAAGTATTGAGTCTGTCTCACTGTGAGCTGATCACAGATGATGGAATTCGTCACCTGGGGAATGGGGCCTGC GCCCATGACCAGCTGGAGGTGATTGAGCTGGACAACTGCCCACTAATCACAGATGCATCCCTGGAGCACTTGAAGAGCTGTCATAGCCTT GAGCGGATAGAACTCTATGACTGCCAGCAAATCACACGGGCTGGAATCAAGAGACTCAGGACCCATTTACCCAATATTAAAGTCCACGCC TACTTCGCACCTGTCACTCCACCCCCATCAGTAGGGGGCAGCAGACAGCGCTTCTGCAGATGCTGCATCATCCTATGACAATGGAGGTGG TCAACCTTGGCGAACTGAGTATTTAATGACACTTCTAGAGCTACCGTGGAGTCTCTCCAGTGGAAGCAACCCCAGTGTTCTGAGCAAGGG TTACAAAGTGAGGGAGGGCAGTGTCCAGATCCCCAGAGCCACACATACATACACATACACACCCTTACCCCCATCCACTCTAGCTTTGTG ACCATGGGACTGAAGTTTGTGATGGCTTTTTTATCAAGTAGATTGGTAAAATTTAACCATTCCTGTTGAGGTGCCCATAAGAAAATCATA GGCCAAGATAGGGAGGGGCATTCCAGCAAACCCCGTGTTAATGCTACTGTGGTTTTTAAATTTTTGTCTAGGGGTTTCTTTGGGGATTTT AGAACAGCATCTGCTGTCCTCCGGGGTCAAGAAAAGCATGGAAAGACAATATATGATGTACCCAGGGACCAGAAAGAAAATTTCTTTGCA TCTTAGAAATGGTAGACATTCATTGTGACTAAAGAGCTTCTATGCTTCCTTGTTTCCATGCCAACATGCTGAGCATGCTCACAAAGAAGG CTCGTCCATTCCTCCTGTGTTTTAGTATTTGGCCCAGAGGTTTCCTAAATGGTTGCCTTGAAATCACTGTGGTCCAAATGTAATTCTTAC ACACTCAAATTATCACTGTCTGTAGCACACTTGTGCACCTGTCTTACATTCTCTGTTGCTCCCCCCCACACTCTTGCTCAGTCTGTCACC TGTTCAGTCTGCTTACTCACTCAATTGTTACCCTTTTGCTGTTGTCGTGTTTACAGTTTGCATTTTGAATGATTAGTTGGGATTACCAAA >In-frame_AARSD1_ENST00000427569_chr17_41108221_-_FBXL20_ENST00000577399_chr17_37499494_-_1968nt TTCTCTGCGCGTGCGCCTCCTCACACGCCTGCAGGTATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTG GTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGGAGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACA GTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGACCGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAG GCTGATCATTTCACCCAGACACCCCTGGATCCAGGAAGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAG CATTCAGGGCAGCATCTCATCACGGCAGTTGCTGACCATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCG ATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAAGTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTG AATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTGGAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTT GTTAACATCGAGGGCGTTGATTCCAACATGTGCTGTGGGACCCATGTGAGCAATCTCAGTGACCTTCAGATGTTCTCAAATAGTGATGAA GCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTC TCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGGCCGAGTA GTGGAGAATATTTCAAAACGATGTGGGGGCTTTTTACGAAAGTTAAGTCTTCGTGGATGTCTTGGAGTGGGAGACAATGCATTAAGAACC TTTGCACAAAACTGCAGGAACATTGAAGTACTGAATCTAAATGGGTGTACAAAGACAACAGACGCTACATGTACTAGCCTTAGCAAGTTC TGTTCCAAACTCAGGCACCTTGACTTGGCTTCCTGTACATCAATAACAAACATGTCTCTAAAAGCTCTGAGTGAGGGATGTCCACTGTTG GAGCAGTTGAACATTTCCTGGTGTGACCAAGTAACCAAGGATGGCATTCAAGCACTAGTGAGGGGCTGTGGGGGTCTCAAGGCCTTATTC TTAAAAGGCTGCACGCAGCTAGAAGATGAAGCTCTCAAGTACATAGGTGCACACTGCCCTGAACTGGTGACTTTGAACTTGCAGACTTGC TTGCAAATCACAGATGAAGGTCTCATTACTATATGCAGAGGGTGCCATAAGTTACAATCCCTTTGTGCCTCTGGCTGCTCCAACATCACA GATGCCATCCTGAATGCTCTAGGTCAGAACTGCCCACGGCTTAGAATATTGGAAGTGGCAAGATGTTCTCAATTAACAGATGTGGGCTTT ACCACTCTAGCCAGGAATTGCCATGAACTTGAAAAGATGGACCTGGAAGAGTGTGTTCAGATAACAGATAGCACATTAATCCAACTTTCT ATACACTGTCCTCGACTTCAAGTATTGAGTCTGTCTCACTGTGAGCTGATCACAGATGATGGAATTCGTCACCTGGGGAATGGGGCCTGC GCCCATGACCAGCTGGAGGTGATTGAGCTGGACAACTGCCCACTAATCACAGATGCATCCCTGGAGCACTTGAAGAGCTGTCATAGCCTT GAGCGGATAGAACTCTATGACTGCCAGCAAATCACACGGGCTGGAATCAAGAGACTCAGGACCCATTTACCCAATATTAAAGTCCACGCC |
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FusionGenePPI for AARSD1_FBXL20 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| AARSD1 | ARPC1A, ARPC2, ARPC5, CALR, CALU, EFTUD2, GTF2E1, HARS, LAP3, PFDN1, PFDN5, PPP1R12A, PPP2CB, PRKACA, TRMT10A, RPA1, RPA3, RPRD1B, RPUSD2, SH3GL1, SH3GLB1, SH3GLB2, THG1L, TP53RK, TTC1, UBQLN2, XPO5, FUBP1, NIF3L1, TPD52L2, IRS4, DYNLT1, HECTD1, TUBA1A, HSPB1, SERPINH1, RHOJ, JADE2, TAT, PARVG, TARS, PPP1R14B, SBDS, SEPT2, SEPT8, SRM, TBCB, RGS20, TRIM45, YKT6, MAP3K7, DDHD2, NPHP3, C12orf74, ALKBH2, TAB1, USP10, ALMS1, LUZP1, SASS6, FIGNL1, ERCC6L, SSFA2, FBXO7, RBM14-RBM4, HPS5, POC5, WNK1, HOOK1, RPL23, UBXN1, APAF1, STIL, MLF1, BORA, FAM83H, KIF1A, RAD21, ARRB2, RICTOR, RIC8B, TRAPPC4, BRCA2, PEAK1, NCAPG, TRIP13 | FBXL20 | CUL1, KRAS, YPEL3, PVR, YPEL1, RABGGTB |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for AARSD1_FBXL20 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for AARSD1_FBXL20 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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