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Fusion gene ID: 42829 |
FusionGeneSummary for ZFP90_CBFB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZFP90_CBFB | Fusion gene ID: 42829 | Hgene | Tgene | Gene symbol | ZFP90 | CBFB | Gene ID | 146198 | 865 |
| Gene name | ZFP90 zinc finger protein | core-binding factor subunit beta | |
| Synonyms | FIK|NK10|ZNF756|zfp-90 | PEBP2B | |
| Cytomap | 16q22.1 | 16q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 90 homologFOXP3-interacting KRAB domain-containing proteinzinc finger protein 476zinc finger protein 756 | core-binding factor subunit betaCBF-betaPEA2-betaPEBP2-betaSL3-3 enhancer factor 1 beta subunitSL3-3 enhancer factor 1 subunit betaSL3/AKV core-binding factor beta subunitcore-binding factor beta subunitpolyomavirus enhancer binding protein 2, bet | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8TF47 | Q13951 | |
| Ensembl transtripts involved in fusion gene | ENST00000570884, ENST00000570495, ENST00000563169, ENST00000564323, ENST00000398253, | ENST00000561924, ENST00000290858, ENST00000412916, ENST00000568858, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 3 X 3 X 3=27 |
| # samples | 3 | 3 | |
| ** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ZFP90 [Title/Abstract] AND CBFB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-WE-A8ZQ-06A | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000570884 | ENST00000561924 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| intron-3CDS | ENST00000570884 | ENST00000290858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| intron-3CDS | ENST00000570884 | ENST00000412916 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| intron-intron | ENST00000570884 | ENST00000568858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000570495 | ENST00000561924 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000570495 | ENST00000290858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000570495 | ENST00000412916 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| 5CDS-intron | ENST00000570495 | ENST00000568858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000563169 | ENST00000561924 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000563169 | ENST00000290858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000563169 | ENST00000412916 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| 5CDS-intron | ENST00000563169 | ENST00000568858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000564323 | ENST00000561924 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000564323 | ENST00000290858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000564323 | ENST00000412916 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| 5CDS-intron | ENST00000564323 | ENST00000568858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000398253 | ENST00000561924 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000398253 | ENST00000290858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| In-frame | ENST00000398253 | ENST00000412916 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
| 5CDS-intron | ENST00000398253 | ENST00000568858 | ZFP90 | chr16 | 68573728 | + | CBFB | chr16 | 67116116 | + |
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FusionProtFeatures for ZFP90_CBFB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZFP90 | CBFB |
| Inhibits the transcriptional repressor activity of RESTby inhibiting its binding to DNA, thereby derepressingtranscription of REST target genes. {ECO:0000269|PubMed:21284946}. Isoform 2: Acts as a bridge between FOXP3 and thecorepressor TRIM28, and is required for the transcriptionalrepressor activity of FOXP3 in regulatory T-cells (Treg).{ECO:0000269|PubMed:23543754}. | Forms the heterodimeric complex core-binding factor(CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNXmembers modulate the transcription of their target genes throughrecognizing the core consensus binding sequence 5'-TGTGGT-3', orvery rarely, 5'-TGCGGT-3', within their regulatory regions viatheir runt domain, while CBFB is a non-DNA-binding regulatorysubunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core siteof a number of enhancers and promoters, including murine leukemiavirus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3and GM-CSF promoters. CBF complexes repress ZBTB7B transcriptionfactor during cytotoxic (CD8+) T cell development. They bind toRUNX-binding sequence within the ZBTB7B locus acting astranscriptional silencer and allowing for cytotoxic T celldifferentiation. {ECO:0000250|UniProtKB:Q08024}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ZFP90_CBFB |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_66aa >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_66aa >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_66aa >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_61aa >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_66aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_198nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGAT >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_198nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGAT >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_198nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGAT >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_183nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCC >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_198nt ATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAA TTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_554nt CGGGCCTCTGGGAAGTGTAGTTCGCGCGCCCGGCGTGGACCCGGGGTTGCAGGAGCGAGGCTCCGAGTGCGCAGGCGCACTTCCAGTTCT GCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGGAGATAACCGAGG CTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGCTCCTGCCCCGGA GCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGA GGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAAC TGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGT >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_2801nt CGGGCCTCTGGGAAGTGTAGTTCGCGCGCCCGGCGTGGACCCGGGGTTGCAGGAGCGAGGCTCCGAGTGCGCAGGCGCACTTCCAGTTCT GCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGGAGATAACCGAGG CTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGCTCCTGCCCCGGA GCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGA GGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCTGCTGGCAGTAAC TGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGT GTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGG TCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAG CATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAG CTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCAT TTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCC ATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAG CTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTT TTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAG TACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGT TCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTAT TCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAA TCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGC TGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAG TTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCA AATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATT AAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTC AGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTA TATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAA ATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTG TACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACT TTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAA GGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTA GCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTAT TAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATT AAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTTGTTTAATTTACTTTCACAATAAACTTCTG >In-frame_ZFP90_ENST00000570495_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_2734nt CGGGCCTCTGGGAAGTGTAGTTCGCGCGCCCGGCGTGGACCCGGGGTTGCAGGAGCGAGGCTCCGAGTGCGCAGGCGCACTTCCAGTTCT GCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGGAGATAACCGAGG CTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGCTCCTGCCCCGGA GCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACAGGCCTTTGAAGA GGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGACCCTAGTCCTGG TTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTC TAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACA TCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTT TCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTC ATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGAT GTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCA TTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTAC AGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTT GCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAAC ATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTC TCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAA AGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATC ATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAA ATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTAT TAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGG AAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAA ATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCAT TGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTG TATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGG CCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCC TAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCT GCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAA ATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCT GGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCA TAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTT >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_493nt CAGGCGCACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCA GAATTGGAGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCA GAGGCGGTGATTCTGACTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAG GATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAG GTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAA >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_2740nt CAGGCGCACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCA GAATTGGAGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCA GAGGCGGTGATTCTGACTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAG GATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAG GTGAGAGTTTCACAGCTGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAA ACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACC AGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGAT TATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATT TTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAA AATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGA GCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTAT TTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAAT GCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCA AGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGT ACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTA AAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAA CAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATT TTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCT TCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTA AGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCT TACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTT AAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGA CTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTG AAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACT ATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAG TGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGA TGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTA ATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCA GTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATT GCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTT >In-frame_ZFP90_ENST00000563169_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_2673nt CAGGCGCACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCA GAATTGGAGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCA GAGGCGGTGATTCTGACTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAG GATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAG GCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGT GCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTC TATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCA TGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCT CCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTT TTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCAT TTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCT GTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTT TTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTA CTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTC TGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTC AGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATC AGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTG GGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTT ATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAA TTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAA ATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAG AAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATA TAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAAT TGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTA CAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTT ATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGG GCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGC ACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTA AGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAA >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_476nt ACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGG AGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGC TCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACA GGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCT GCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAG >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_2723nt ACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGG AGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGC TCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACA GGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGCT GCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAG CACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTG GAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTC TAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTA TCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTT TTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGT TTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTT AGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTC TTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTT AGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGT TTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGG CTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGA GACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTT GTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAA AAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATA GGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATG GTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGA CACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTT ACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAG GAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTG GTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTG TTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTA TTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTT TTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAA AACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAA TTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTTGTTTAATTTACTTTCAC >In-frame_ZFP90_ENST00000564323_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_2656nt ACTTCCAGTTCTGCCCCACCGCTGCGGCCATTGTCCGACCCCGGTGCGGCTGAGGCCCCTTTGGGCAGCCCCTCCGCAGATCAGAATTGG AGATAACCGAGGCTTCGGCGGGGGCGGGAGGAGCTGCCCGAGGCTCTGGGTGGGCCGGAGGTCGCGAAATCCGGAGCCCCCCAGAGGCGC TCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAACA GGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAGA CCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACAT ACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAGG CAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAATT TGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTTA ATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTTT GTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTTA TAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTCT GACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGGG TCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTCT TTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTGG TTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAAA GTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATAT TGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAGT TTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTTG CAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTTA GATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCTG AATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTCT GAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATAA ACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAATG CGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTACA CACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTGG TTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAGT AAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGTC TGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATTT GATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTAC >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000561924_chr16_67116116_+_297nt CTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAAC AGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGC TGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATA >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000290858_chr16_67116116_+_2544nt CTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAAC AGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGTGAGAGTTTCACAGC TGCTGGCAGTAACTGGCAAGAAGACAACAAGACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATA GCACAGCAGATGTGTGCTGCCCATCTTTACATACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACT GGAGGTACTACGGTCTATTTCTCAACCTTAGGCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTT CTAATTTTTTAAGCATGTAGCCAGTAATAATTTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACT ATCAACTGTAAAGCTCCTTTTCTTCCACTTTAATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGT TTTCTCTAATCATTTTTTCTATTTTTTTTTTTGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTG TTTTGTTTGCCCCATTTCCTTTTGTGTTTTTATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACT TAGTAGCATAGAGCTGTCTGCCACAGCCTTCTGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACT CTTTCTTTTTTTTTTTTTTAATAGAGACAGGGTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCT TAGCCTCCCAGAGTACTGGGATTACAGGCTCTTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTG TTTTAGCTTCTGTTCTGTAATCATGAGTTTGGTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTG GCTTCTGTTTTATTCAGGGATTTTTTTAAAAAGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGG AGACAGTGATGAATCAGCTACAAAGGTAATATTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTT TGTAAAAACATGCTGGGTGATGAAAGATTAGTTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAA AAAACGTTCACAGTTATATATATGGTATTTTGCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAAT AGGCTTACTGTCAAATTGCAACTTTTTTTTTAGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCAT GGTCACATTTATTAAATGTTACTACATTTCTGAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTG ACACAGTCAATTCAGAAAATGGACTGAAGTCTGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGT TACTTTCATTGTATATAGGTCTTATTTCATAAACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAA GGAGTGTGTTTAAATTGTTACAAACAATAATGCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTT GGTTTTGGTGTTGTACAGCTCACATGTTTACACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGT GTTTTATGTTACTTTATTACAGAGCTCCTTGGTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCT ATTGTCTAGCTAAGGGCTTTCGGTCCACCAGTAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATT TTTCTGTCATTTAGCACCATGCTGCTTCTGTCTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGA AAACTACTTCTATTAAGTTATTGATGCAATTTGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAA ATTCATCTCCATTAAAACTTGCCTTAAGCTACCAGATTGCTTTTGCCACCATTGGCCATACTGTGTGTTTGTTTGTTTAATTTACTTTCA >In-frame_ZFP90_ENST00000398253_chr16_68573728_+_CBFB_ENST00000412916_chr16_67116116_+_2477nt CTCCTGCCCCGGAGCCGGGCCCTGGCGAGGCAGGAATGGCCCCGAGGCCTCCGACCGCCGCGCCCCAGCAGGAGGATGCATTAGCACAAC AGGCCTTTGAAGAGGCTCGGAGAAGGACACGCGAATTTGAAGATAGAGACAGGTCTCATCGGGAGGAAATGGAGGCAAGAAGACAACAAG ACCCTAGTCCTGGTTCCAATTTAGGTGGTGGTGATGACCTCAAACTTCGTTAATTAATAGCACAGCAGATGTGTGCTGCCCATCTTTACA TACACATTGCTTCTAGTTGGCAGAAATAATTGATTAAAAGACCAGAAACTGTGATAACTGGAGGTACTACGGTCTATTTCTCAACCTTAG GCAGTAATAGACATCACAAACTGCCATGGTTTTGCACTATGATTATAATACCTGCATTTCTAATTTTTTAAGCATGTAGCCAGTAATAAT TTGAAGTTTTTTTTCTATGCAAGCTTACCTTGTTGGCATTATTTTAGGGAGTTGAAACTATCAACTGTAAAGCTCCTTTTCTTCCACTTT AATTTAAAAGTTCATGTCATTTAAAAACAAGTCAAGAAATTAAAATTGTATCAGAGGGTTTTCTCTAATCATTTTTTCTATTTTTTTTTT TGTACTTCTAGATGTTTTGGTTATACAGCTTCATTTTAGATGAGCATTCTTATTTTTTGTTTTGTTTGCCCCATTTCCTTTTGTGTTTTT ATAGTCTATAGCATTTTAAAACTGCTGATGTTGTTTGCATTATTTACAGGCTAAAAACTTAGTAGCATAGAGCTGTCTGCCACAGCCTTC TGACAAAGTTTACAGTTATTAAAGTTGCAGTATCCTTTTAAATGCTAGTAATCAGCACTCTTTCTTTTTTTTTTTTTTAATAGAGACAGG GTCTCGCAGTGTTGCCCAGGCTGGTCTCGAACTCCTGGCATCAAGCGATCCTCCTGCCTTAGCCTCCCAGAGTACTGGGATTACAGGCTC TTTCTTTTTAAACATAAAAGTTTTAAATTGGTATTAACTCTGTACTCTGCCCTAGATTGTTTTAGCTTCTGTTCTGTAATCATGAGTTTG GTTGGAGATATTCTCCATAGATGATCTTCTACTGAAATGCCTAAAGAAGTCACAGGCTGGCTTCTGTTTTATTCAGGGATTTTTTTAAAA AGTCAATCAGAAAAGGGATACTGGAGCTTCTTCATGTATGTAACAGCATATTAAACTGGAGACAGTGATGAATCAGCTACAAAGGTAATA TTGTATTAAAATCATGTTTAAGATAGCTGCTTTTATGTGTATTTTATATTGCATGCTTTTGTAAAAACATGCTGGGTGATGAAAGATTAG TTTTAGAGAGAAAATGTTCATCTGTGCAGAGGATGCATTTTCTTCCATTAATTCTGGAAAAAACGTTCACAGTTATATATATGGTATTTT GCAAAAGGACTATTAATAGAACCTTTTGAGATGAATTAATGTAAGAATATTTTTTAAATAGGCTTACTGTCAAATTGCAACTTTTTTTTT AGATACAGAGTGGAAAACAGTGCTAAGTCATTTGGCACCTCCTTACAAATATTTTTCATGGTCACATTTATTAAATGTTACTACATTTCT GAATTTTTGAAAAATGTATTTTATCATTAAATGGCATTATTTTAAAGGGTGAAAAACTGACACAGTCAATTCAGAAAATGGACTGAAGTC TGAATAAGGTCATTGCATTTAAAAAGCATATAACTGTACTTGACTGATGAGGGAGGTGTTACTTTCATTGTATATAGGTCTTATTTCATA AACAGATATCCTGTATCAAATAAAAGTATTTGTTATATATTTGAAGTTATGCATGGAAAGGAGTGTGTTTAAATTGTTACAAACAATAAT GCGTCATTAAAGGCCATGCTGATCTTGCATAACTATAAGTACTATGAATGAATTTGGTTGGTTTTGGTGTTGTACAGCTCACATGTTTAC ACACTCAGTGCCCTAATTTCCCCTGAGGGAATCGCTTTTTAAGTGATCCTTACAGTGGTGTTTTATGTTACTTTATTACAGAGCTCCTTG GTTTTTTACTTCTGCACTTAAATTTTTTTAAATAACATGATGATGGTACATTTTCCTCTATTGTCTAGCTAAGGGCTTTCGGTCCACCAG TAAATAAGATCAAATGCTCTTAAATGTTCCTGTTACCATCCTAATGTAAATACTGGATTTTTCTGTCATTTAGCACCATGCTGCTTCTGT CTGTCTTAATGCTGGCATTAAGATCATGAGCCCTTTTTCTCCAGTAGTACAGGCTTTGAAAACTACTTCTATTAAGTTATTGATGCAATT TGATATTTTTTCATAATCTATATTTAAACAAAATTACATCATTGCATCATCTTTTCTAAATTCATCTCCATTAAAACTTGCCTTAAGCTA 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FusionGenePPI for ZFP90_CBFB |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ZFP90 | CBFB | CHGB, RUNX1, MYOD1, RUNX3, COPRS, KMT2A, ELAVL1, CUL5, APOBEC3G, MYC, RAB2A, TCEB1, RNF7, TCEB2, RUNX2, ARL6IP6, SERPINB5, SLC25A32, TAS2R41, CRIP1, GALK1, PPIA, SOD1, NFATC1, GCHFR, G3BP1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ZFP90_CBFB |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZFP90_CBFB |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CBFB | C0023467 | Leukemia, Myelocytic, Acute | 2 | CTD_human |
| Tgene | CBFB | C0005941 | Bone Diseases, Developmental | 1 | CTD_human |
| Tgene | CBFB | C0008925 | Cleft Palate | 1 | CTD_human |
| Tgene | CBFB | C0018798 | Congenital Heart Defects | 1 | CTD_human |
| Tgene | CBFB | C0023479 | Acute myelomonocytic leukemia | 1 | CTD_human;ORPHANET |
| Tgene | CBFB | C0029396 | Heterotopic Ossification | 1 | CTD_human |
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