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Fusion gene ID: 4273 |
FusionGeneSummary for BNC2_UHRF2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BNC2_UHRF2 | Fusion gene ID: 4273 | Hgene | Tgene | Gene symbol | BNC2 | UHRF2 | Gene ID | 54796 | 115426 |
| Gene name | basonuclin 2 | ubiquitin like with PHD and ring finger domains 2 | |
| Synonyms | BSN2 | NIRF|RNF107|TDRD23|URF2 | |
| Cytomap | 9p22.3-p22.2 | 9p24.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein basonuclin-2 | E3 ubiquitin-protein ligase UHRF2Np95-like ring finger proteinRING finger protein 107RING-type E3 ubiquitin transferase UHRF2np95/ICBP90-like RING finger proteinnuclear protein 97nuclear zinc finger protein NP97ubiquitin-like PHD and RING finger do | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q6ZN30 | Q96PU4 | |
| Ensembl transtripts involved in fusion gene | ENST00000380672, ENST00000380667, ENST00000545497, ENST00000380666, ENST00000471301, | ENST00000276893, ENST00000381373, ENST00000485617, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 5 X 4 X 5=100 |
| # samples | 5 | 5 | |
| ** MAII score | log2(5/32*10)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BNC2 [Title/Abstract] AND UHRF2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | UHRF2 | GO:0016567 | protein ubiquitination | 14741369 |
| Tgene | UHRF2 | GO:0051865 | protein autoubiquitination | 14741369 |
| Tgene | UHRF2 | GO:0071158 | positive regulation of cell cycle arrest | 15178429 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-AB2E-01A | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000380672 | ENST00000276893 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| In-frame | ENST00000380672 | ENST00000381373 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| 5CDS-intron | ENST00000380672 | ENST00000485617 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| In-frame | ENST00000380667 | ENST00000276893 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| In-frame | ENST00000380667 | ENST00000381373 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| 5CDS-intron | ENST00000380667 | ENST00000485617 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| intron-3CDS | ENST00000545497 | ENST00000276893 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| intron-3CDS | ENST00000545497 | ENST00000381373 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| intron-intron | ENST00000545497 | ENST00000485617 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| In-frame | ENST00000380666 | ENST00000276893 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| In-frame | ENST00000380666 | ENST00000381373 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| 5CDS-intron | ENST00000380666 | ENST00000485617 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| intron-3CDS | ENST00000471301 | ENST00000276893 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| intron-3CDS | ENST00000471301 | ENST00000381373 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
| intron-intron | ENST00000471301 | ENST00000485617 | BNC2 | chr9 | 16870644 | - | UHRF2 | chr9 | 6420912 | + |
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FusionProtFeatures for BNC2_UHRF2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BNC2 | UHRF2 |
| Probable transcription factor specific for skinkeratinocytes. May play a role in the differentiation ofspermatozoa and oocytes. | E3 ubiquitin-protein ligase that is an intermolecularhub protein in the cell cycle network. Through cooperative DNA andhistone binding, may contribute to a tighter epigenetic control ofgene expression in differentiated cells. Ubiquitinates cyclins,CCND1 and CCNE1, in an apparently phosphorylation-independentmanner and induces G1 arrest. Also ubiquitinates PCNP leading toits degradation by the proteasome. E3 SUMO-, but not ubiquitin-,protein ligase for ZNF131. {ECO:0000269|PubMed:12176013,ECO:0000269|PubMed:14741369, ECO:0000269|PubMed:15178429,ECO:0000269|PubMed:15361834, ECO:0000269|PubMed:21952639,ECO:0000269|PubMed:23404503}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >UHRF2 | chr9:16870644 | chr9:6420912 | ENST00000276893 | + | 0 | 16 | 448_612 | 51 | 803 | Domain | YDG |
| Tgene | >UHRF2 | chr9:16870644 | chr9:6420912 | ENST00000276893 | + | 0 | 16 | 344_395 | 51 | 803 | Zinc finger | PHD-type |
| Tgene | >UHRF2 | chr9:16870644 | chr9:6420912 | ENST00000276893 | + | 0 | 16 | 733_772 | 51 | 803 | Zinc finger | RING-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380666 | - | 1 | 7 | 534_614 | 1 | 904 | Compositional bias | Pro-rich |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380672 | - | 1 | 7 | 534_614 | 1 | 1100 | Compositional bias | Pro-rich |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380666 | - | 1 | 7 | 1035_1058 | 1 | 904 | Zinc finger | C2H2-type 3 |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380666 | - | 1 | 7 | 1063_1090 | 1 | 904 | Zinc finger | C2H2-type 4 |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380666 | - | 1 | 7 | 441_464 | 1 | 904 | Zinc finger | C2H2-type 1 |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380666 | - | 1 | 7 | 833_856 | 1 | 904 | Zinc finger | C2H2-type 2 |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380672 | - | 1 | 7 | 1035_1058 | 1 | 1100 | Zinc finger | C2H2-type 3 |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380672 | - | 1 | 7 | 1063_1090 | 1 | 1100 | Zinc finger | C2H2-type 4 |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380672 | - | 1 | 7 | 441_464 | 1 | 1100 | Zinc finger | C2H2-type 1 |
| Hgene | >BNC2 | chr9:16870644 | chr9:6420912 | ENST00000380672 | - | 1 | 7 | 833_856 | 1 | 1100 | Zinc finger | C2H2-type 2 |
| Tgene | UHRF2 | chr9:16870644 | chr9:6420912 | ENST00000276893 | + | 0 | 16 | 1_78 | 51 | 803 | Domain | Ubiquitin-like |
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FusionGeneSequence for BNC2_UHRF2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_BNC2_ENST00000380672_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_753aa MLENGYTLFDYDVGLNDIIQLLVRPDPDHLPGTSTQIEAKPCSNSPPKVKKAPRVGPSNQPSTSARARLIDPGFGIYKVNELVDARDVGL GAWFEAHIHSVTRASDGQSRGKTPLKNGSSCKRTNGNIKHKSKENTNKLDSVPSTSNSDCVAADEDVIYHIQYDEYPESGTLEMNVKDLR PRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGGSEGTLNDCKIISVDEIFKIERPGAHPLSFAD GKFLRRNDPECDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVPEEEYWYCPSCKTDSSEVVKAGERLKMSK KKAKMPSASTESRRDWGRGMACVGRTRECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVD RGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKV VKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYPSDKEGKKPKGQSKKQPSGTTKRPISDDDCPSASKVYKA SDSAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLVEGPNFLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPA >In-frame_BNC2_ENST00000380672_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_87aa >In-frame_BNC2_ENST00000380667_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_753aa MLENGYTLFDYDVGLNDIIQLLVRPDPDHLPGTSTQIEAKPCSNSPPKVKKAPRVGPSNQPSTSARARLIDPGFGIYKVNELVDARDVGL GAWFEAHIHSVTRASDGQSRGKTPLKNGSSCKRTNGNIKHKSKENTNKLDSVPSTSNSDCVAADEDVIYHIQYDEYPESGTLEMNVKDLR PRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGGSEGTLNDCKIISVDEIFKIERPGAHPLSFAD GKFLRRNDPECDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVPEEEYWYCPSCKTDSSEVVKAGERLKMSK KKAKMPSASTESRRDWGRGMACVGRTRECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVD RGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKV VKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYPSDKEGKKPKGQSKKQPSGTTKRPISDDDCPSASKVYKA SDSAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLVEGPNFLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPA >In-frame_BNC2_ENST00000380667_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_87aa >In-frame_BNC2_ENST00000380666_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_753aa MLENGYTLFDYDVGLNDIIQLLVRPDPDHLPGTSTQIEAKPCSNSPPKVKKAPRVGPSNQPSTSARARLIDPGFGIYKVNELVDARDVGL GAWFEAHIHSVTRASDGQSRGKTPLKNGSSCKRTNGNIKHKSKENTNKLDSVPSTSNSDCVAADEDVIYHIQYDEYPESGTLEMNVKDLR PRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISRTKKELRVKIFLGGSEGTLNDCKIISVDEIFKIERPGAHPLSFAD GKFLRRNDPECDLCGGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVPEEEYWYCPSCKTDSSEVVKAGERLKMSK KKAKMPSASTESRRDWGRGMACVGRTRECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVD RGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKV VKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYPSDKEGKKPKGQSKKQPSGTTKRPISDDDCPSASKVYKA SDSAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLVEGPNFLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPA >In-frame_BNC2_ENST00000380666_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_87aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_BNC2_ENST00000380672_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_2259nt ATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTT CCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAG CCATCTACATCAGCTCGTGCCCGTCTTATTGATCCTGGCTTTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTT GGTGCTTGGTTTGAAGCACACATACATAGTGTTACTAGAGCTTCTGATGGACAGTCACGTGGCAAAACTCCACTGAAGAATGGCAGTTCT TGTAAAAGGACTAATGGAAATATAAAGCATAAATCCAAAGAGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGT GTTGCTGCTGATGAAGACGTTATTTACCATATCCAGTATGATGAATACCCAGAAAGCGGTACTCTAGAAATGAATGTCAAGGATCTTAGA CCACGAGCTAGAACCATTTTGAAATGGAATGAACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGA GGATTCTGGTTTGATGCAGAAATTACCACATTGAAGACAATCTCAAGGACCAAAAAAGAACTTCGTGTGAAAATTTTCCTGGGGGGTTCT GAAGGAACATTAAATGACTGCAAGATAATATCTGTAGATGAAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGAT GGAAAGTTTTTAAGGCGAAATGACCCTGAATGTGACCTGTGTGGTGGAGACCCAGAAAAGAAATGTCATTCTTGCTCCTGTCGTGTATGT GGTGGGAAACATGAACCCAACATGCAGCTTCTGTGTGATGAATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAA GTCCCAGAAGAGGAATACTGGTATTGTCCTTCTTGTAAAACTGATTCCAGTGAAGTTGTAAAGGCTGGTGAAAGACTCAAGATGAGTAAA AAGAAAGCAAAGATGCCGTCAGCTAGTACTGAAAGCCGAAGAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACT ATTGTCCCTTCTAATCATTATGGACCCATTCCTGGTATTCCTGTTGGATCAACTTGGAGATTTAGAGTTCAGGTGAGCGAAGCAGGTGTT CACAGACCCCATGTTGGTGGAATTCATGGTCGAAGTAATGATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGAC CGAGGTGATGAGTTCACATACACTGGAAGCGGTGGTAAAAATCTTGCTGGTAACAAAAGAATTGGTGCACCTTCAGCTGATCAAACATTA ACAAACATGAACAGGGCATTGGCCCTAAACTGTGATGCTCCATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAG CCAGTCAGAGTGATACGCAGTTTTAAAGGGAGGAAGATCAGCAAATATGCTCCTGAAGAAGGCAACAGATATGATGGCATTTATAAGGTG GTGAAATACTGGCCAGAGATTTCATCAAGCCATGGATTCTTGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGG ACCTCTGAAGGAATAGAACGGTCAAGGAGATTATGTCTACGTTTACAGTATCCAGCAGGTTACCCTTCAGATAAAGAAGGGAAGAAGCCT AAAGGACAGTCAAAGAAGCAGCCCAGTGGAACCACAAAAAGGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCA TCAGATTCAGCAGAAGCAATTGAGGCTTTTCAACTAACTCCTCAACAGCAACATCTCATCAGAGAAGATTGTCAAAACCAGAAGCTGTGG GATGAAGTGCTTTCACATCTTGTGGAAGGACCAAATTTTCTGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTT TACCAGCCTGTGACAACTGAGTGCTTCCACAATGTCTGTAAAGATTGCCTACAGCGCTCCTTTAAGGCACAGGTTTTCTCCTGCCCTGCT TGCCGGCATGATCTTGGCCAGAATTACATCATGATTCCCAATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAA >In-frame_BNC2_ENST00000380672_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_261nt ATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTT CCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAG >In-frame_BNC2_ENST00000380667_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_2259nt ATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTT CCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAG CCATCTACATCAGCTCGTGCCCGTCTTATTGATCCTGGCTTTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTT GGTGCTTGGTTTGAAGCACACATACATAGTGTTACTAGAGCTTCTGATGGACAGTCACGTGGCAAAACTCCACTGAAGAATGGCAGTTCT TGTAAAAGGACTAATGGAAATATAAAGCATAAATCCAAAGAGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGT GTTGCTGCTGATGAAGACGTTATTTACCATATCCAGTATGATGAATACCCAGAAAGCGGTACTCTAGAAATGAATGTCAAGGATCTTAGA CCACGAGCTAGAACCATTTTGAAATGGAATGAACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGA GGATTCTGGTTTGATGCAGAAATTACCACATTGAAGACAATCTCAAGGACCAAAAAAGAACTTCGTGTGAAAATTTTCCTGGGGGGTTCT GAAGGAACATTAAATGACTGCAAGATAATATCTGTAGATGAAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGAT GGAAAGTTTTTAAGGCGAAATGACCCTGAATGTGACCTGTGTGGTGGAGACCCAGAAAAGAAATGTCATTCTTGCTCCTGTCGTGTATGT GGTGGGAAACATGAACCCAACATGCAGCTTCTGTGTGATGAATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAA GTCCCAGAAGAGGAATACTGGTATTGTCCTTCTTGTAAAACTGATTCCAGTGAAGTTGTAAAGGCTGGTGAAAGACTCAAGATGAGTAAA AAGAAAGCAAAGATGCCGTCAGCTAGTACTGAAAGCCGAAGAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACT ATTGTCCCTTCTAATCATTATGGACCCATTCCTGGTATTCCTGTTGGATCAACTTGGAGATTTAGAGTTCAGGTGAGCGAAGCAGGTGTT CACAGACCCCATGTTGGTGGAATTCATGGTCGAAGTAATGATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGAC CGAGGTGATGAGTTCACATACACTGGAAGCGGTGGTAAAAATCTTGCTGGTAACAAAAGAATTGGTGCACCTTCAGCTGATCAAACATTA ACAAACATGAACAGGGCATTGGCCCTAAACTGTGATGCTCCATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAG CCAGTCAGAGTGATACGCAGTTTTAAAGGGAGGAAGATCAGCAAATATGCTCCTGAAGAAGGCAACAGATATGATGGCATTTATAAGGTG GTGAAATACTGGCCAGAGATTTCATCAAGCCATGGATTCTTGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGG ACCTCTGAAGGAATAGAACGGTCAAGGAGATTATGTCTACGTTTACAGTATCCAGCAGGTTACCCTTCAGATAAAGAAGGGAAGAAGCCT AAAGGACAGTCAAAGAAGCAGCCCAGTGGAACCACAAAAAGGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCA TCAGATTCAGCAGAAGCAATTGAGGCTTTTCAACTAACTCCTCAACAGCAACATCTCATCAGAGAAGATTGTCAAAACCAGAAGCTGTGG GATGAAGTGCTTTCACATCTTGTGGAAGGACCAAATTTTCTGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTT TACCAGCCTGTGACAACTGAGTGCTTCCACAATGTCTGTAAAGATTGCCTACAGCGCTCCTTTAAGGCACAGGTTTTCTCCTGCCCTGCT TGCCGGCATGATCTTGGCCAGAATTACATCATGATTCCCAATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAA >In-frame_BNC2_ENST00000380667_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_261nt ATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTT CCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAG >In-frame_BNC2_ENST00000380666_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_2259nt ATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTT CCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAG CCATCTACATCAGCTCGTGCCCGTCTTATTGATCCTGGCTTTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTT GGTGCTTGGTTTGAAGCACACATACATAGTGTTACTAGAGCTTCTGATGGACAGTCACGTGGCAAAACTCCACTGAAGAATGGCAGTTCT TGTAAAAGGACTAATGGAAATATAAAGCATAAATCCAAAGAGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGT GTTGCTGCTGATGAAGACGTTATTTACCATATCCAGTATGATGAATACCCAGAAAGCGGTACTCTAGAAATGAATGTCAAGGATCTTAGA CCACGAGCTAGAACCATTTTGAAATGGAATGAACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGA GGATTCTGGTTTGATGCAGAAATTACCACATTGAAGACAATCTCAAGGACCAAAAAAGAACTTCGTGTGAAAATTTTCCTGGGGGGTTCT GAAGGAACATTAAATGACTGCAAGATAATATCTGTAGATGAAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGAT GGAAAGTTTTTAAGGCGAAATGACCCTGAATGTGACCTGTGTGGTGGAGACCCAGAAAAGAAATGTCATTCTTGCTCCTGTCGTGTATGT GGTGGGAAACATGAACCCAACATGCAGCTTCTGTGTGATGAATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAA GTCCCAGAAGAGGAATACTGGTATTGTCCTTCTTGTAAAACTGATTCCAGTGAAGTTGTAAAGGCTGGTGAAAGACTCAAGATGAGTAAA AAGAAAGCAAAGATGCCGTCAGCTAGTACTGAAAGCCGAAGAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACT ATTGTCCCTTCTAATCATTATGGACCCATTCCTGGTATTCCTGTTGGATCAACTTGGAGATTTAGAGTTCAGGTGAGCGAAGCAGGTGTT CACAGACCCCATGTTGGTGGAATTCATGGTCGAAGTAATGATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGAC CGAGGTGATGAGTTCACATACACTGGAAGCGGTGGTAAAAATCTTGCTGGTAACAAAAGAATTGGTGCACCTTCAGCTGATCAAACATTA ACAAACATGAACAGGGCATTGGCCCTAAACTGTGATGCTCCATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAG CCAGTCAGAGTGATACGCAGTTTTAAAGGGAGGAAGATCAGCAAATATGCTCCTGAAGAAGGCAACAGATATGATGGCATTTATAAGGTG GTGAAATACTGGCCAGAGATTTCATCAAGCCATGGATTCTTGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGG ACCTCTGAAGGAATAGAACGGTCAAGGAGATTATGTCTACGTTTACAGTATCCAGCAGGTTACCCTTCAGATAAAGAAGGGAAGAAGCCT AAAGGACAGTCAAAGAAGCAGCCCAGTGGAACCACAAAAAGGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCA TCAGATTCAGCAGAAGCAATTGAGGCTTTTCAACTAACTCCTCAACAGCAACATCTCATCAGAGAAGATTGTCAAAACCAGAAGCTGTGG GATGAAGTGCTTTCACATCTTGTGGAAGGACCAAATTTTCTGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTT TACCAGCCTGTGACAACTGAGTGCTTCCACAATGTCTGTAAAGATTGCCTACAGCGCTCCTTTAAGGCACAGGTTTTCTCCTGCCCTGCT TGCCGGCATGATCTTGGCCAGAATTACATCATGATTCCCAATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAA >In-frame_BNC2_ENST00000380666_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_261nt ATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTT CCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_BNC2_ENST00000380672_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_3192nt GCGGCCGCTAAGAGGAGACCAAGAGGCGGGGGCTGCACTTGACAACCAGCATGCCGAGATGTTGGAAAATGGATATACCTTATTTGATTA TGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTTCCTGGCACATCTACACAGATTGAGGCTAAACC CTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTACATCAGCTCGTGCCCGTCTTATTGA TCCTGGCTTTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTTGGTGCTTGGTTTGAAGCACACATACATAGTGT TACTAGAGCTTCTGATGGACAGTCACGTGGCAAAACTCCACTGAAGAATGGCAGTTCTTGTAAAAGGACTAATGGAAATATAAAGCATAA ATCCAAAGAGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGTGTTGCTGCTGATGAAGACGTTATTTACCATAT CCAGTATGATGAATACCCAGAAAGCGGTACTCTAGAAATGAATGTCAAGGATCTTAGACCACGAGCTAGAACCATTTTGAAATGGAATGA ACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGAGGATTCTGGTTTGATGCAGAAATTACCACATT GAAGACAATCTCAAGGACCAAAAAAGAACTTCGTGTGAAAATTTTCCTGGGGGGTTCTGAAGGAACATTAAATGACTGCAAGATAATATC TGTAGATGAAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGATGGAAAGTTTTTAAGGCGAAATGACCCTGAATG TGACCTGTGTGGTGGAGACCCAGAAAAGAAATGTCATTCTTGCTCCTGTCGTGTATGTGGTGGGAAACATGAACCCAACATGCAGCTTCT GTGTGATGAATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAAGTCCCAGAAGAGGAATACTGGTATTGTCCTTC TTGTAAAACTGATTCCAGTGAAGTTGTAAAGGCTGGTGAAAGACTCAAGATGAGTAAAAAGAAAGCAAAGATGCCGTCAGCTAGTACTGA AAGCCGAAGAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACTATTGTCCCTTCTAATCATTATGGACCCATTCC TGGTATTCCTGTTGGATCAACTTGGAGATTTAGAGTTCAGGTGAGCGAAGCAGGTGTTCACAGACCCCATGTTGGTGGAATTCATGGTCG AAGTAATGATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGACCGAGGTGATGAGTTCACATACACTGGAAGCGG TGGTAAAAATCTTGCTGGTAACAAAAGAATTGGTGCACCTTCAGCTGATCAAACATTAACAAACATGAACAGGGCATTGGCCCTAAACTG TGATGCTCCATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAGCCAGTCAGAGTGATACGCAGTTTTAAAGGGAG GAAGATCAGCAAATATGCTCCTGAAGAAGGCAACAGATATGATGGCATTTATAAGGTGGTGAAATACTGGCCAGAGATTTCATCAAGCCA TGGATTCTTGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGGACCTCTGAAGGAATAGAACGGTCAAGGAGATT ATGTCTACGTTTACAGTATCCAGCAGGTTACCCTTCAGATAAAGAAGGGAAGAAGCCTAAAGGACAGTCAAAGAAGCAGCCCAGTGGAAC CACAAAAAGGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCATCAGATTCAGCAGAAGCAATTGAGGCTTTTCA ACTAACTCCTCAACAGCAACATCTCATCAGAGAAGATTGTCAAAACCAGAAGCTGTGGGATGAAGTGCTTTCACATCTTGTGGAAGGACC AAATTTTCTGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTTTACCAGCCTGTGACAACTGAGTGCTTCCACAA TGTCTGTAAAGATTGCCTACAGCGCTCCTTTAAGGCACAGGTTTTCTCCTGCCCTGCTTGCCGGCATGATCTTGGCCAGAATTACATCAT GATTCCCAATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAAGGACGATGATCTGCCTGCTTTCACTGTGTTGT TCATGGTGGCTTTTTGGACAATAAAGAATCTAAAATGGGTGGGGAGGGTGGAAGAAATGGTGGACTGTATCTCTCACGTTCTGAAGCAGC TAATCCTCTTTCCCACATAGCCATCATCTTGTGTGTGTAGTAAGAGGCCCATTTCTCAACTGTCTTTTAAATATCTAAAGGTAGTTCCTG TAACAACTAGTTTTAATGAGTAAAAAGTCAAAGCCTCAGCTCTAGTTGATATCCAAGTTATGATTTATTTTGCAACTACCTCAGGACAGA AAAGATTTATGGGGATTTTAAAAATCATTGAATAACTAGTTAAATGAAATTTTAGCTACACACTGCCTCCCAAATATTAGTTGTGCCTGG TTCTTGTAATTTGATTTTACAGAAAAGGAAATGACACTTGAGATCCTTGGAATGAACACAGCTTCTAAAGTGTGCATATACTTTTTTAAC GTCTCTTCTTCCATTACAATGTGTGTTTTGCAAGGACAGGTTCATTTTTTTTAGCCCACTTTGTGAACTCCATTGTGCTTTTTTCTGGTG TTTTATGCAAGTTGACTACTAATGACTAATGAGAACAATAATGAATGCATTGTTGCTGCATTAGTGTAATGTGGTGTGGTTTTGCACTTA AAAGAGGTATTCATATGCTCTAGTTGTAAATGTTCATGAAAATCCACTTCTCTACTAGTCGAACTGCTTTTAGTGTCTCACCAGTGGTTT TACATCTGCAGAGTTTTGAGGGCTGTGCTGACCTTTGAGAGGATTTGAAATTGCTTCATATTGTGATCCTAAATTTTATATTCACTATAT >In-frame_BNC2_ENST00000380672_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_637nt GCGGCCGCTAAGAGGAGACCAAGAGGCGGGGGCTGCACTTGACAACCAGCATGCCGAGATGTTGGAAAATGGATATACCTTATTTGATTA TGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTTCCTGGCACATCTACACAGATTGAGGCTAAACC CTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTACATCAGCTCGTGCCCGTCTTATTGA TCCTGGCTTTGGAATATATAAGGGTCTGGCTCTGTCACCCAGGCTGTAGTGCAGTGACGTGAACACGGCTCGCTGTAGCCTTGACCTGCT GGGGTCAAGTGATCTTCCTGCTCGGCCTCCCAAAGTGCTGGGATACAGGCGTGAGCCACCATGCCCGGCTAACTTAGATCTTTGATATCT TGATTAGTTCTTTCTTTACATATTTAATATTTTGCTTTATTTCTGGTAGCTTTGTTTTTGATGCAATTATTATATATGGTTATCTTCTAA AATAGTAATCTGTTTGCTGATATAGAGAAATGAAATTGATTTATTTGGCTTTTGTAACCAGCAACCTTTTCAAATCTAATAAATTGTGTA >In-frame_BNC2_ENST00000380667_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_3217nt CGGCGGCCGAGGGGCTGGTCCAGGCGCGGCCGCTAAGAGGAGACCAAGAGGCGGGGGCTGCACTTGACAACCAGCATGCCGAGATGTTGG AAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTTCCTGGCA CATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTA CATCAGCTCGTGCCCGTCTTATTGATCCTGGCTTTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTTGGTGCTT GGTTTGAAGCACACATACATAGTGTTACTAGAGCTTCTGATGGACAGTCACGTGGCAAAACTCCACTGAAGAATGGCAGTTCTTGTAAAA GGACTAATGGAAATATAAAGCATAAATCCAAAGAGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGTGTTGCTG CTGATGAAGACGTTATTTACCATATCCAGTATGATGAATACCCAGAAAGCGGTACTCTAGAAATGAATGTCAAGGATCTTAGACCACGAG CTAGAACCATTTTGAAATGGAATGAACTAAATGTTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGAGGATTCT GGTTTGATGCAGAAATTACCACATTGAAGACAATCTCAAGGACCAAAAAAGAACTTCGTGTGAAAATTTTCCTGGGGGGTTCTGAAGGAA CATTAAATGACTGCAAGATAATATCTGTAGATGAAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGATGGAAAGT TTTTAAGGCGAAATGACCCTGAATGTGACCTGTGTGGTGGAGACCCAGAAAAGAAATGTCATTCTTGCTCCTGTCGTGTATGTGGTGGGA AACATGAACCCAACATGCAGCTTCTGTGTGATGAATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAAGTCCCAG AAGAGGAATACTGGTATTGTCCTTCTTGTAAAACTGATTCCAGTGAAGTTGTAAAGGCTGGTGAAAGACTCAAGATGAGTAAAAAGAAAG CAAAGATGCCGTCAGCTAGTACTGAAAGCCGAAGAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACTATTGTCC CTTCTAATCATTATGGACCCATTCCTGGTATTCCTGTTGGATCAACTTGGAGATTTAGAGTTCAGGTGAGCGAAGCAGGTGTTCACAGAC CCCATGTTGGTGGAATTCATGGTCGAAGTAATGATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGACCGAGGTG ATGAGTTCACATACACTGGAAGCGGTGGTAAAAATCTTGCTGGTAACAAAAGAATTGGTGCACCTTCAGCTGATCAAACATTAACAAACA TGAACAGGGCATTGGCCCTAAACTGTGATGCTCCATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAGCCAGTCA GAGTGATACGCAGTTTTAAAGGGAGGAAGATCAGCAAATATGCTCCTGAAGAAGGCAACAGATATGATGGCATTTATAAGGTGGTGAAAT ACTGGCCAGAGATTTCATCAAGCCATGGATTCTTGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGGACCTCTG AAGGAATAGAACGGTCAAGGAGATTATGTCTACGTTTACAGTATCCAGCAGGTTACCCTTCAGATAAAGAAGGGAAGAAGCCTAAAGGAC AGTCAAAGAAGCAGCCCAGTGGAACCACAAAAAGGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCATCAGATT CAGCAGAAGCAATTGAGGCTTTTCAACTAACTCCTCAACAGCAACATCTCATCAGAGAAGATTGTCAAAACCAGAAGCTGTGGGATGAAG TGCTTTCACATCTTGTGGAAGGACCAAATTTTCTGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTTTACCAGC CTGTGACAACTGAGTGCTTCCACAATGTCTGTAAAGATTGCCTACAGCGCTCCTTTAAGGCACAGGTTTTCTCCTGCCCTGCTTGCCGGC ATGATCTTGGCCAGAATTACATCATGATTCCCAATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAAGGACGAT GATCTGCCTGCTTTCACTGTGTTGTTCATGGTGGCTTTTTGGACAATAAAGAATCTAAAATGGGTGGGGAGGGTGGAAGAAATGGTGGAC TGTATCTCTCACGTTCTGAAGCAGCTAATCCTCTTTCCCACATAGCCATCATCTTGTGTGTGTAGTAAGAGGCCCATTTCTCAACTGTCT TTTAAATATCTAAAGGTAGTTCCTGTAACAACTAGTTTTAATGAGTAAAAAGTCAAAGCCTCAGCTCTAGTTGATATCCAAGTTATGATT TATTTTGCAACTACCTCAGGACAGAAAAGATTTATGGGGATTTTAAAAATCATTGAATAACTAGTTAAATGAAATTTTAGCTACACACTG CCTCCCAAATATTAGTTGTGCCTGGTTCTTGTAATTTGATTTTACAGAAAAGGAAATGACACTTGAGATCCTTGGAATGAACACAGCTTC TAAAGTGTGCATATACTTTTTTAACGTCTCTTCTTCCATTACAATGTGTGTTTTGCAAGGACAGGTTCATTTTTTTTAGCCCACTTTGTG AACTCCATTGTGCTTTTTTCTGGTGTTTTATGCAAGTTGACTACTAATGACTAATGAGAACAATAATGAATGCATTGTTGCTGCATTAGT GTAATGTGGTGTGGTTTTGCACTTAAAAGAGGTATTCATATGCTCTAGTTGTAAATGTTCATGAAAATCCACTTCTCTACTAGTCGAACT GCTTTTAGTGTCTCACCAGTGGTTTTACATCTGCAGAGTTTTGAGGGCTGTGCTGACCTTTGAGAGGATTTGAAATTGCTTCATATTGTG >In-frame_BNC2_ENST00000380667_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_662nt CGGCGGCCGAGGGGCTGGTCCAGGCGCGGCCGCTAAGAGGAGACCAAGAGGCGGGGGCTGCACTTGACAACCAGCATGCCGAGATGTTGG AAAATGGATATACCTTATTTGATTATGATGTTGGACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTTCCTGGCA CATCTACACAGATTGAGGCTAAACCCTGTTCTAATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTA CATCAGCTCGTGCCCGTCTTATTGATCCTGGCTTTGGAATATATAAGGGTCTGGCTCTGTCACCCAGGCTGTAGTGCAGTGACGTGAACA CGGCTCGCTGTAGCCTTGACCTGCTGGGGTCAAGTGATCTTCCTGCTCGGCCTCCCAAAGTGCTGGGATACAGGCGTGAGCCACCATGCC CGGCTAACTTAGATCTTTGATATCTTGATTAGTTCTTTCTTTACATATTTAATATTTTGCTTTATTTCTGGTAGCTTTGTTTTTGATGCA ATTATTATATATGGTTATCTTCTAAAATAGTAATCTGTTTGCTGATATAGAGAAATGAAATTGATTTATTTGGCTTTTGTAACCAGCAAC >In-frame_BNC2_ENST00000380666_chr9_16870644_-_UHRF2_ENST00000276893_chr9_6420912_+_3274nt GAGGCCCGGAGGAACTCGGAGGGGGAGGGAGAGAAAGGCCGAGACGGAGGGAGCCAGCGGCGGCCGAGGGGCTGGTCCAGGCGCGGCCGC TAAGAGGAGACCAAGAGGCGGGGGCTGCACTTGACAACCAGCATGCCGAGATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTG GACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTTCCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTA ATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTACATCAGCTCGTGCCCGTCTTATTGATCCTGGCT TTGGAATATATAAGGTAAATGAATTGGTGGATGCCAGAGATGTCGGCCTTGGTGCTTGGTTTGAAGCACACATACATAGTGTTACTAGAG CTTCTGATGGACAGTCACGTGGCAAAACTCCACTGAAGAATGGCAGTTCTTGTAAAAGGACTAATGGAAATATAAAGCATAAATCCAAAG AGAACACAAATAAATTGGACAGTGTACCCTCTACGTCTAATTCAGACTGTGTTGCTGCTGATGAAGACGTTATTTACCATATCCAGTATG ATGAATACCCAGAAAGCGGTACTCTAGAAATGAATGTCAAGGATCTTAGACCACGAGCTAGAACCATTTTGAAATGGAATGAACTAAATG TTGGTGATGTGGTAATGGTTAATTATAATGTAGAAAGTCCTGGACAAAGAGGATTCTGGTTTGATGCAGAAATTACCACATTGAAGACAA TCTCAAGGACCAAAAAAGAACTTCGTGTGAAAATTTTCCTGGGGGGTTCTGAAGGAACATTAAATGACTGCAAGATAATATCTGTAGATG AAATCTTCAAGATTGAGAGACCTGGAGCCCATCCCCTTTCATTTGCAGATGGAAAGTTTTTAAGGCGAAATGACCCTGAATGTGACCTGT GTGGTGGAGACCCAGAAAAGAAATGTCATTCTTGCTCCTGTCGTGTATGTGGTGGGAAACATGAACCCAACATGCAGCTTCTGTGTGATG AATGTAATGTGGCTTATCATATTTACTGTCTGAATCCACCTTTGGATAAAGTCCCAGAAGAGGAATACTGGTATTGTCCTTCTTGTAAAA CTGATTCCAGTGAAGTTGTAAAGGCTGGTGAAAGACTCAAGATGAGTAAAAAGAAAGCAAAGATGCCGTCAGCTAGTACTGAAAGCCGAA GAGACTGGGGCAGGGGAATGGCTTGTGTTGGTCGTACGAGAGAATGTACTATTGTCCCTTCTAATCATTATGGACCCATTCCTGGTATTC CTGTTGGATCAACTTGGAGATTTAGAGTTCAGGTGAGCGAAGCAGGTGTTCACAGACCCCATGTTGGTGGAATTCATGGTCGAAGTAATG ATGGGGCTTATTCTCTTGTACTGGCTGGTGGATTTGCGGATGAAGTCGACCGAGGTGATGAGTTCACATACACTGGAAGCGGTGGTAAAA ATCTTGCTGGTAACAAAAGAATTGGTGCACCTTCAGCTGATCAAACATTAACAAACATGAACAGGGCATTGGCCCTAAACTGTGATGCTC CATTGGATGATAAAATTGGAGCAGAGTCTCGGAATTGGAGAGCTGGTAAGCCAGTCAGAGTGATACGCAGTTTTAAAGGGAGGAAGATCA GCAAATATGCTCCTGAAGAAGGCAACAGATATGATGGCATTTATAAGGTGGTGAAATACTGGCCAGAGATTTCATCAAGCCATGGATTCT TGGTTTGGCGCTATCTTTTAAGAAGAGATGATGTTGAACCTGCTCCTTGGACCTCTGAAGGAATAGAACGGTCAAGGAGATTATGTCTAC GTTTACAGTATCCAGCAGGTTACCCTTCAGATAAAGAAGGGAAGAAGCCTAAAGGACAGTCAAAGAAGCAGCCCAGTGGAACCACAAAAA GGCCAATTTCAGATGATGACTGTCCAAGTGCCTCCAAAGTGTACAAAGCATCAGATTCAGCAGAAGCAATTGAGGCTTTTCAACTAACTC CTCAACAGCAACATCTCATCAGAGAAGATTGTCAAAACCAGAAGCTGTGGGATGAAGTGCTTTCACATCTTGTGGAAGGACCAAATTTTC TGAAAAAATTGGAACAATCTTTTATGTGCGTTTGCTGTCAGGAGCTAGTTTACCAGCCTGTGACAACTGAGTGCTTCCACAATGTCTGTA AAGATTGCCTACAGCGCTCCTTTAAGGCACAGGTTTTCTCCTGCCCTGCTTGCCGGCATGATCTTGGCCAGAATTACATCATGATTCCCA ATGAGATTCTGCAGACTCTACTTGACCTTTTCTTCCCTGGCTACAGCAAAGGACGATGATCTGCCTGCTTTCACTGTGTTGTTCATGGTG GCTTTTTGGACAATAAAGAATCTAAAATGGGTGGGGAGGGTGGAAGAAATGGTGGACTGTATCTCTCACGTTCTGAAGCAGCTAATCCTC TTTCCCACATAGCCATCATCTTGTGTGTGTAGTAAGAGGCCCATTTCTCAACTGTCTTTTAAATATCTAAAGGTAGTTCCTGTAACAACT AGTTTTAATGAGTAAAAAGTCAAAGCCTCAGCTCTAGTTGATATCCAAGTTATGATTTATTTTGCAACTACCTCAGGACAGAAAAGATTT ATGGGGATTTTAAAAATCATTGAATAACTAGTTAAATGAAATTTTAGCTACACACTGCCTCCCAAATATTAGTTGTGCCTGGTTCTTGTA ATTTGATTTTACAGAAAAGGAAATGACACTTGAGATCCTTGGAATGAACACAGCTTCTAAAGTGTGCATATACTTTTTTAACGTCTCTTC TTCCATTACAATGTGTGTTTTGCAAGGACAGGTTCATTTTTTTTAGCCCACTTTGTGAACTCCATTGTGCTTTTTTCTGGTGTTTTATGC AAGTTGACTACTAATGACTAATGAGAACAATAATGAATGCATTGTTGCTGCATTAGTGTAATGTGGTGTGGTTTTGCACTTAAAAGAGGT ATTCATATGCTCTAGTTGTAAATGTTCATGAAAATCCACTTCTCTACTAGTCGAACTGCTTTTAGTGTCTCACCAGTGGTTTTACATCTG CAGAGTTTTGAGGGCTGTGCTGACCTTTGAGAGGATTTGAAATTGCTTCATATTGTGATCCTAAATTTTATATTCACTATATTCCCTAAA >In-frame_BNC2_ENST00000380666_chr9_16870644_-_UHRF2_ENST00000381373_chr9_6420912_+_719nt GAGGCCCGGAGGAACTCGGAGGGGGAGGGAGAGAAAGGCCGAGACGGAGGGAGCCAGCGGCGGCCGAGGGGCTGGTCCAGGCGCGGCCGC TAAGAGGAGACCAAGAGGCGGGGGCTGCACTTGACAACCAGCATGCCGAGATGTTGGAAAATGGATATACCTTATTTGATTATGATGTTG GACTGAATGATATAATTCAGCTGCTAGTTCGCCCAGACCCTGATCATCTTCCTGGCACATCTACACAGATTGAGGCTAAACCCTGTTCTA ATAGTCCACCTAAAGTAAAGAAAGCTCCGAGGGTAGGACCTTCCAATCAGCCATCTACATCAGCTCGTGCCCGTCTTATTGATCCTGGCT TTGGAATATATAAGGGTCTGGCTCTGTCACCCAGGCTGTAGTGCAGTGACGTGAACACGGCTCGCTGTAGCCTTGACCTGCTGGGGTCAA GTGATCTTCCTGCTCGGCCTCCCAAAGTGCTGGGATACAGGCGTGAGCCACCATGCCCGGCTAACTTAGATCTTTGATATCTTGATTAGT TCTTTCTTTACATATTTAATATTTTGCTTTATTTCTGGTAGCTTTGTTTTTGATGCAATTATTATATATGGTTATCTTCTAAAATAGTAA |
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FusionGenePPI for BNC2_UHRF2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| BNC2 | IRF6, CHCHD10 | UHRF2 | UBE2D2, UBE2D3, UBE2D4, UBE2W, UBE2K, PCNP, HDAC1, CDK1, CDK2, CDK4, CDK6, PCNA, RB1, TP53, MCL1, BCL2L1, BAX, CTNNB1, FYN, LCK, LYN, BCAR1, RAD51, YY1, JAK3, CD27, PTPRC, SKP1, CCNA2, CCND1, CCNB1, CCNE1, HIST1H3A, DNMT1, DNMT3A, DNMT3B, EHMT2, UHRF1, TFAP4, UBE2D1, TWF2, USP7, ZNF131, UBE2I, ATXN1, SMAD4, MPG, E2F1, RBCK1, TRIM8, TRIM27, UHRF2, KRAS, ZNF618, PARP1, HSPA1L, XRCC5, XRCC6, KAT5, GMPS, RPA1, CDK11B, BCLAF1, CDK11A, KIF4A, CHD3, CUL4B, CTBP2, CDC73, CHERP, PSMD5, PUF60, GATAD2B, LUC7L2, FANCI, MSH3, ERCC2, NCAPG2, DIDO1, MRE11A, NCAPD3, SUZ12, CHAF1B, LUC7L3, RCOR1, KDM2A, ATR, FANCD2, MBD3, NR2F2, CDC16, CHD8, PBRM1, EED, FBXL18, KDM4B, BRD3, CHD2, TLK1, ZNF574, BTAF1, TCF7L2, BMI1, PIN1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | UHRF2 | chr9:16870644 | chr9:6420912 | ENST00000276893 | + | 0 | 16 | 194_288 | 51 | 803 | PCNP |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for BNC2_UHRF2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BNC2_UHRF2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | BNC2 | C0008925 | Cleft Palate | 1 | CTD_human |
| Hgene | BNC2 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Hgene | BNC2 | C0919267 | ovarian neoplasm | 1 | CTD_human |
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