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Fusion gene ID: 42147 |
FusionGeneSummary for XBP1_TTC28 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: XBP1_TTC28 | Fusion gene ID: 42147 | Hgene | Tgene | Gene symbol | XBP1 | TTC28 | Gene ID | 7494 | 23331 |
| Gene name | X-box binding protein 1 | tetratricopeptide repeat domain 28 | |
| Synonyms | TREB-5|TREB5|XBP-1|XBP2 | TPRBK | |
| Cytomap | 22q12.1|22q12 | 22q12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | X-box-binding protein 1tax-responsive element-binding protein 5 | tetratricopeptide repeat protein 28TPR repeat protein 28TPR repeat-containing big gene cloned at KeioTPR-containing big gene cloned at Keio | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P17861 | Q96AY4 | |
| Ensembl transtripts involved in fusion gene | ENST00000216037, ENST00000403532, ENST00000405219, ENST00000344347, | ENST00000397906, ENST00000490475, | |
| Fusion gene scores | * DoF score | 7 X 7 X 4=196 | 5 X 4 X 4=80 |
| # samples | 9 | 6 | |
| ** MAII score | log2(9/196*10)=-1.12285674778553 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/80*10)=-0.415037499278844 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: XBP1 [Title/Abstract] AND TTC28 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | XBP1 | GO:0002639 | positive regulation of immunoglobulin production | 11460154 |
| Hgene | XBP1 | GO:0008284 | positive regulation of cell proliferation | 25656649 |
| Hgene | XBP1 | GO:0030335 | positive regulation of cell migration | 25656649 |
| Hgene | XBP1 | GO:0035470 | positive regulation of vascular wound healing | 25656649 |
| Hgene | XBP1 | GO:0045579 | positive regulation of B cell differentiation | 11460154 |
| Hgene | XBP1 | GO:0045582 | positive regulation of T cell differentiation | 11460154 |
| Hgene | XBP1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 8657566 |
| Hgene | XBP1 | GO:0071222 | cellular response to lipopolysaccharide | 11460154 |
| Hgene | XBP1 | GO:1900100 | positive regulation of plasma cell differentiation | 11460154 |
| Hgene | XBP1 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | 19135031 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | TGCT | TCGA-2X-A9D6-01A | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| TCGA | LD | TGCT | TCGA-4K-AAAL-01A | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000216037 | ENST00000397906 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| 5CDS-intron | ENST00000216037 | ENST00000490475 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| Frame-shift | ENST00000403532 | ENST00000397906 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| 5CDS-intron | ENST00000403532 | ENST00000490475 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| Frame-shift | ENST00000405219 | ENST00000397906 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| 5CDS-intron | ENST00000405219 | ENST00000490475 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| In-frame | ENST00000344347 | ENST00000397906 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| 5CDS-intron | ENST00000344347 | ENST00000490475 | XBP1 | chr22 | 29192035 | - | TTC28 | chr22 | 28559587 | - |
| In-frame | ENST00000216037 | ENST00000397906 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| 5CDS-intron | ENST00000216037 | ENST00000490475 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| intron-3CDS | ENST00000403532 | ENST00000397906 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| intron-intron | ENST00000403532 | ENST00000490475 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| In-frame | ENST00000405219 | ENST00000397906 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| 5CDS-intron | ENST00000405219 | ENST00000490475 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| In-frame | ENST00000344347 | ENST00000397906 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
| 5CDS-intron | ENST00000344347 | ENST00000490475 | XBP1 | chr22 | 29195045 | - | TTC28 | chr22 | 29025818 | - |
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FusionProtFeatures for XBP1_TTC28 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| XBP1 | TTC28 |
| Functions as a transcription factor during endoplasmicreticulum (ER) stress by regulating the unfolded protein response(UPR). Required for cardiac myogenesis and hepatogenesis duringembryonic development, and the development of secretory tissuessuch as exocrine pancreas and salivary gland (By similarity).Involved in terminal differentiation of B lymphocytes to plasmacells and production of immunoglobulins (PubMed:11460154).Modulates the cellular response to ER stress in a PIK3R-dependentmanner (PubMed:20348923). Binds to the cis-acting X box present inthe promoter regions of major histocompatibility complex class IIgenes (PubMed:8349596). Involved in VEGF-induced endothelial cell(EC) proliferation and retinal blood vessel formation duringembryonic development but also for angiogenesis in adult tissuesunder ischemic conditions. Functions also as a major regulator ofthe UPR in obesity-induced insulin resistance and type 2 diabetesfor the management of obesity and diabetes prevention (Bysimilarity). {ECO:0000250|UniProtKB:O35426,ECO:0000269|PubMed:11460154, ECO:0000269|PubMed:20348923,ECO:0000269|PubMed:8349596}. Isoform 1: Plays a role in the unconventionalcytoplasmic splicing processing of its own mRNA triggered by theendoplasmic reticulum (ER) transmembrane endoribonuclease ENR1:upon ER stress, the emerging XBP1 polypeptide chain, as part of amRNA-ribosome-nascent chain (R-RNC) complex, cotranslationallyrecruits its own unprocessed mRNA through transient docking to theER membrane and translational pausing, therefore facilitatingefficient IRE1-mediated XBP1 mRNA isoform 2 production(PubMed:19394296, PubMed:21233347). In endothelial cells (EC),associated with KDR, promotes IRE1-mediated XBP1 mRNA isoform 2productions in a vascular endothelial growth factor (VEGF)-dependent manner, leading to EC proliferation and angiogenesis(PubMed:23529610). Functions as a negative feed-back regulator ofthe potent transcription factor XBP1 isoform 2 protein levelsthrough proteasome-mediated degradation, thus preventing theconstitutive activation of the ER stress response signalingpathway (PubMed:16461360, PubMed:25239945). Inhibits thetransactivation activity of XBP1 isoform 2 in myeloma cells (Bysimilarity). Acts as a weak transcriptional factor(PubMed:8657566). Together with HDAC3, contributes to theactivation of NFE2L2-mediated HMOX1 transcription factor geneexpression in a PI(3)K/mTORC2/Akt-dependent signaling pathwayleading to EC survival under disturbed flow/oxidative stress(PubMed:25190803). Binds to the ER stress response element (ERSE)upon ER stress (PubMed:11779464). Binds to the consensus 5'-GATGACGTG[TG]N(3)[AT]T-3' sequence related to cAMP responsiveelement (CRE)-like sequences (PubMed:8657566). Binds the Tax-responsive element (TRE) present in the long terminal repeat (LTR)of T-cell leukemia virus type 1 (HTLV-I) and to the TPA responseelements (TRE) (PubMed:2321018, PubMed:2196176, PubMed:1903538,PubMed:8657566). Associates preferentially to the HDAC3 genepromoter region in a static flow-dependent manner(PubMed:25190803). Binds to the CDH5/VE-cadherin gene promoterregion (PubMed:19416856). {ECO:0000250|UniProtKB:O35426,ECO:0000269|PubMed:11779464, ECO:0000269|PubMed:16461360,ECO:0000269|PubMed:1903538, ECO:0000269|PubMed:19394296,ECO:0000269|PubMed:19416856, ECO:0000269|PubMed:21233347,ECO:0000269|PubMed:2196176, ECO:0000269|PubMed:2321018,ECO:0000269|PubMed:23529610, ECO:0000269|PubMed:25190803,ECO:0000269|PubMed:25239945, ECO:0000269|PubMed:8657566}. Isoform 2: Functions as a stress-inducible potenttranscriptional activator during endoplasmic reticulum (ER) stressby inducing unfolded protein response (UPR) target genes viabinding to the UPR element (UPRE). Up-regulates target genesencoding ER chaperones and ER-associated degradation (ERAD)components to enhance the capacity of productive folding anddegradation mechanism, respectively, in order to maintain thehomeostasis of the ER under ER stress (PubMed:11779464,PubMed:25239945). Plays a role in the production ofimmunoglobulins and interleukin-6 in the presence of stimulirequired for plasma cell differentiation (By similarity). Inducesphospholipid biosynthesis and ER expansion (PubMed:15466483).Contributes to the VEGF-induced endothelial cell (EC) growth andproliferation in a Akt/GSK-dependent and/or -independent signalingpathway, respectively, leading to beta-catenin nucleartranslocation and E2F2 gene expression (PubMed:23529610). Promotesumbilical vein EC apoptosis and atherosclerotisis development in acaspase-dependent signaling pathway, and contributes to VEGF-induced EC proliferation and angiogenesis in adult tissues underischemic conditions (PubMed:19416856, PubMed:23529610). Involvedin the regulation of endostatin-induced autophagy in EC throughBECN1 transcriptional activation (PubMed:23184933). Plays a roleas an oncogene by promoting tumor progression: stimulates zincfinger protein SNAI1 transcription to induce epithelial-to-mesenchymal (EMT) transition, cell migration and invasion ofbreast cancer cells (PubMed:25280941). Involved in adipocytedifferentiation by regulating lipogenic gene expression duringlactation. Plays a role in the survival of both dopaminergicneurons of the substantia nigra pars compacta (SNpc), bymaintaining protein homeostasis and of myeloma cells. Increasesinsulin sensitivity in the liver as a response to a highcarbohydrate diet, resulting in improved glucose tolerance.Improves also glucose homeostasis in an ER stress- and/or insulin-independent manner through both binding and proteasome-induceddegradation of the transcription factor FOXO1, hence resulting insuppression of gluconeogenic genes expression and in a reductionof blood glucose levels. Controls the induction of de novo fattyacid synthesis in hepatocytes by regulating the expression of asubset of lipogenic genes in an ER stress- and UPR-independentmanner (By similarity). Associates preferentially to the HDAC3gene promoter region in a disturbed flow-dependent manner(PubMed:25190803). Binds to the BECN1 gene promoter region(PubMed:23184933). Binds to the CDH5/VE-cadherin gene promoterregion (PubMed:19416856). Binds to the ER stress response element(ERSE) upon ER stress (PubMed:11779464). Binds to the 5'-CCACG-3'motif in the PPARG promoter (By similarity).{ECO:0000250|UniProtKB:O35426, ECO:0000269|PubMed:11779464,ECO:0000269|PubMed:15466483, ECO:0000269|PubMed:19416856,ECO:0000269|PubMed:23184933, ECO:0000269|PubMed:23529610,ECO:0000269|PubMed:25190803, ECO:0000269|PubMed:25239945,ECO:0000269|PubMed:25280941}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 72_94 | 108 | 262 | Region | Basic motif |
| Hgene | XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 75_92 | 108 | 262 | Region | Nuclear localization signal (NLS)%3B in isoforms 1 and isoform 2 |
| Hgene | XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 72_94 | 108 | 377 | Region | Basic motif |
| Hgene | XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 75_92 | 108 | 377 | Region | Nuclear localization signal (NLS)%3B in isoforms 1 and isoform 2 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 1948_2006 | 34 | 2482 | Compositional bias | Note=Ser-rich |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 2201_2335 | 34 | 2482 | Compositional bias | Note=Ser-rich |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 1037_1070 | 34 | 2482 | Repeat | Note=TPR 25 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 1077_1110 | 34 | 2482 | Repeat | Note=TPR 26 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 1117_1150 | 34 | 2482 | Repeat | Note=TPR 27 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 1169_1202 | 34 | 2482 | Repeat | Note=TPR 28 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 126_159 | 34 | 2482 | Repeat | Note=TPR 3 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 196_229 | 34 | 2482 | Repeat | Note=TPR 4 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 234_267 | 34 | 2482 | Repeat | Note=TPR 5 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 274_307 | 34 | 2482 | Repeat | Note=TPR 6 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 314_347 | 34 | 2482 | Repeat | Note=TPR 7 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 354_387 | 34 | 2482 | Repeat | Note=TPR 8 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 394_427 | 34 | 2482 | Repeat | Note=TPR 9 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 434_467 | 34 | 2482 | Repeat | Note=TPR 10 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 474_507 | 34 | 2482 | Repeat | Note=TPR 11 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 514_547 | 34 | 2482 | Repeat | Note=TPR 12 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 554_587 | 34 | 2482 | Repeat | Note=TPR 13 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 58_91 | 34 | 2482 | Repeat | Note=TPR 1 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 594_627 | 34 | 2482 | Repeat | Note=TPR 14 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 634_667 | 34 | 2482 | Repeat | Note=TPR 15 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 674_707 | 34 | 2482 | Repeat | Note=TPR 16 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 714_747 | 34 | 2482 | Repeat | Note=TPR 17 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 754_787 | 34 | 2482 | Repeat | Note=TPR 18 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 794_827 | 34 | 2482 | Repeat | Note=TPR 19 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 834_867 | 34 | 2482 | Repeat | Note=TPR 20 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 877_910 | 34 | 2482 | Repeat | Note=TPR 21 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 917_950 | 34 | 2482 | Repeat | Note=TPR 22 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 93_125 | 34 | 2482 | Repeat | Note=TPR 2 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 957_990 | 34 | 2482 | Repeat | Note=TPR 23 |
| Tgene | >TTC28 | chr22:29195045 | chr22:29025818 | ENST00000397906 | - | 0 | 23 | 997_1030 | 34 | 2482 | Repeat | Note=TPR 24 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 70_133 | 108 | 262 | Domain | bZIP |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 70_133 | 108 | 377 | Domain | bZIP |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 235_261 | 108 | 262 | Region | Necessary for the translational pausing of its own mRNA |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 98_133 | 108 | 262 | Region | Leucine-zipper |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 235_261 | 108 | 377 | Region | Necessary for the translational pausing of its own mRNA |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 98_133 | 108 | 377 | Region | Leucine-zipper |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 1_185 | 108 | 262 | Topological domain | Cytoplasmic |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 204_261 | 108 | 262 | Topological domain | Lumenal |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 1_185 | 108 | 377 | Topological domain | Cytoplasmic |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 204_261 | 108 | 377 | Topological domain | Lumenal |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000216037 | - | 2 | 5 | 186_203 | 108 | 262 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Hgene | >XBP1 | chr22:29195045 | chr22:29025818 | ENST00000344347 | - | 2 | 6 | 186_203 | 108 | 377 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
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FusionGeneSequence for XBP1_TTC28 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_XBP1_ENST00000344347_chr22_29192035_-_TTC28_ENST00000397906_chr22_28559587_-_2362aa MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDR KKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAAGAGPVVTPPEHLPM DSGGIDSSDSEAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNK REEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNL GIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAH DRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQD LALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDR RLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNM GITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAM GSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYH QLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQL GRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAF ADLLVERQTGQQDSDPYSPVTIDQILEMVNGQRGLVLYYSLAAGYLYSWLLAPGAGIVKFHEHYLGENTVENSSDFQASSSVTLPTATGS ALEQHIASVREALGVESHYSRACASSETESEAGDIMDQQFEEMNNKLNSVTDPTGFLRMVRRNNLFNRSCQSMTSLFSNTVSPTQDGTSS LPRRQSSFAKPPLRALYDLLIAPMEGGLMHSSGPVGRHRQLILVLEGELYLIPFALLKGSSSNEYLYERFGLLAVPSIRSLSVQSKSHLR KNPPTYSSSTSMAAVIGNPKLPSAVMDRWLWGPMPSAEEEAYMVSELLGCQPLVGSVATKERVMSALTQAECVHFATHISWKLSALVLTP SMDGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPPLQELLLTAADVLDLQLPVKLVVLGSSQESNSKVTADGVIALTRAFLAAGA QCVLVSLWPVPVAASKMFIHAFYSSLLNGLKASAALGEAMKVVQSSKAFSHPSNWAGFMLIGSDVKLNSPSSLIGQALTEILQHPERARD ALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPPTSGLPAAVFFPTSDPGDRLQQCSSTLQSLLGLPNP ALQALCKLITASETGEQLISRAVKNMVGMLHQVLVQLQAGEKEQDLASAPIQVSISVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGK QANRRTVHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQQPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPEG GSEGGGPGGRQDHDRSKNAYLQRSTLPRSQLPPQTRPAGNKDEEEYEGFSIISNEPLATYQENRNTCFSPDHKQPQPGTAGGMRVSVSSK GSISTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEESNPKLDPQELAQKILEETQSHLIAVERLQRSGGQVSKS NNPEDGVQAPSSTAVFRASETSAFSRPVLSHQKSQPSPVTVKPKPPARSSSLPKVSSGYSSPTTSEMSIKDSPSQHSGRPSPGCDSQTSQ LDQPLFKLKYPSSPYSAHISKSPRNMSPSSGHQSPAGSAPSPALSYSSAGSARSSPADAPDIDKLKMAAIDEKVQAVHNLKMFWQSTPQH STGPMKIFRGAPGTMTSKRDVLSLLNLSPRHNKKEEGVDKLELKELSLQQHDGAPPKAPPNGHWRTETTSLGSLPLPAGPPATAPARPLR >In-frame_XBP1_ENST00000216037_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_2556aa MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDR KKARMSELEQQVVDLEEEIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQ QYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDSLEPTYQQLQKMKLDKSPF VVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFS KGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQC HEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAED LKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQAST HGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYC LGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKF YEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQK LKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQ AKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGV YQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQA VMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHD EALAVAERGRTRAFADLLVERQTGQQDSDPYSPVTIDQILEMVNGQRGLVLYYSLAAGYLYSWLLAPGAGIVKFHEHYLGENTVENSSDF QASSSVTLPTATGSALEQHIASVREALGVESHYSRACASSETESEAGDIMDQQFEEMNNKLNSVTDPTGFLRMVRRNNLFNRSCQSMTSL FSNTVSPTQDGTSSLPRRQSSFAKPPLRALYDLLIAPMEGGLMHSSGPVGRHRQLILVLEGELYLIPFALLKGSSSNEYLYERFGLLAVP SIRSLSVQSKSHLRKNPPTYSSSTSMAAVIGNPKLPSAVMDRWLWGPMPSAEEEAYMVSELLGCQPLVGSVATKERVMSALTQAECVHFA THISWKLSALVLTPSMDGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPPLQELLLTAADVLDLQLPVKLVVLGSSQESNSKVTAD GVIALTRAFLAAGAQCVLVSLWPVPVAASKMFIHAFYSSLLNGLKASAALGEAMKVVQSSKAFSHPSNWAGFMLIGSDVKLNSPSSLIGQ ALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPPTSGLPAAVFFPTSDPGDRLQQ CSSTLQSLLGLPNPALQALCKLITASETGEQLISRAVKNMVGMLHQVLVQLQAGEKEQDLASAPIQVSISVQLWRLPGCHEFLAALGFDL CEVGQEEVILKTGKQANRRTVHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQQPPFSPTGADSIASDAISVYSLS SIASSMSFVSKPEGGSEGGGPGGRQDHDRSKNAYLQRSTLPRSQLPPQTRPAGNKDEEEYEGFSIISNEPLATYQENRNTCFSPDHKQPQ PGTAGGMRVSVSSKGSISTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEESNPKLDPQELAQKILEETQSHLIA VERLQRSGGQVSKSNNPEDGVQAPSSTAVFRASETSAFSRPVLSHQKSQPSPVTVKPKPPARSSSLPKVSSGYSSPTTSEMSIKDSPSQH SGRPSPGCDSQTSQLDQPLFKLKYPSSPYSAHISKSPRNMSPSSGHQSPAGSAPSPALSYSSAGSARSSPADAPDIDKLKMAAIDEKVQA VHNLKMFWQSTPQHSTGPMKIFRGAPGTMTSKRDVLSLLNLSPRHNKKEEGVDKLELKELSLQQHDGAPPKAPPNGHWRTETTSLGSLPL >In-frame_XBP1_ENST00000405219_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_2506aa MRAPVFQALLLCGRRLVVQPLNSDMRKLKNRVAAQTARDRKKARMSELEQQVVDLEEEIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSN QACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQD PKSLQLLVGMVEAAMKSPMRDSLEPTYQQLQKMKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAYWS LGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALAS HKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQE LMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRA YGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCS RGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEEC QKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQE LSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDR GRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSL HSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERA VVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASAL FETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAFADLLVERQTGQQDSDPYSPVTIDQILEMVNGQRGLV LYYSLAAGYLYSWLLAPGAGIVKFHEHYLGENTVENSSDFQASSSVTLPTATGSALEQHIASVREALGVESHYSRACASSETESEAGDIM DQQFEEMNNKLNSVTDPTGFLRMVRRNNLFNRSCQSMTSLFSNTVSPTQDGTSSLPRRQSSFAKPPLRALYDLLIAPMEGGLMHSSGPVG RHRQLILVLEGELYLIPFALLKGSSSNEYLYERFGLLAVPSIRSLSVQSKSHLRKNPPTYSSSTSMAAVIGNPKLPSAVMDRWLWGPMPS AEEEAYMVSELLGCQPLVGSVATKERVMSALTQAECVHFATHISWKLSALVLTPSMDGNPASSKSSFGHPYTIPESLRVQDDASDGESIS DCPPLQELLLTAADVLDLQLPVKLVVLGSSQESNSKVTADGVIALTRAFLAAGAQCVLVSLWPVPVAASKMFIHAFYSSLLNGLKASAAL GEAMKVVQSSKAFSHPSNWAGFMLIGSDVKLNSPSSLIGQALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVG GIPGWQALLTAVGFRLDPPTSGLPAAVFFPTSDPGDRLQQCSSTLQSLLGLPNPALQALCKLITASETGEQLISRAVKNMVGMLHQVLVQ LQAGEKEQDLASAPIQVSISVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGKQANRRTVHFALQSLLSLFDSTELPKRLSLDSSSSLE SLASAQSVSNALPLGYQQPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPEGGSEGGGPGGRQDHDRSKNAYLQRSTLPRSQLPPQTR PAGNKDEEEYEGFSIISNEPLATYQENRNTCFSPDHKQPQPGTAGGMRVSVSSKGSISTPNSPVKMTLIPSPNSPFQKVGKLASSDTGES DQSSTETDSTVKSQEESNPKLDPQELAQKILEETQSHLIAVERLQRSGGQVSKSNNPEDGVQAPSSTAVFRASETSAFSRPVLSHQKSQP SPVTVKPKPPARSSSLPKVSSGYSSPTTSEMSIKDSPSQHSGRPSPGCDSQTSQLDQPLFKLKYPSSPYSAHISKSPRNMSPSSGHQSPA GSAPSPALSYSSAGSARSSPADAPDIDKLKMAAIDEKVQAVHNLKMFWQSTPQHSTGPMKIFRGAPGTMTSKRDVLSLLNLSPRHNKKEE >In-frame_XBP1_ENST00000344347_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_2556aa MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDR KKARMSELEQQVVDLEEEIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQ QYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDSLEPTYQQLQKMKLDKSPF VVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFS KGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQC HEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAED LKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQAST HGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYC LGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKF YEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQK LKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQ AKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGV YQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQA VMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHD EALAVAERGRTRAFADLLVERQTGQQDSDPYSPVTIDQILEMVNGQRGLVLYYSLAAGYLYSWLLAPGAGIVKFHEHYLGENTVENSSDF QASSSVTLPTATGSALEQHIASVREALGVESHYSRACASSETESEAGDIMDQQFEEMNNKLNSVTDPTGFLRMVRRNNLFNRSCQSMTSL FSNTVSPTQDGTSSLPRRQSSFAKPPLRALYDLLIAPMEGGLMHSSGPVGRHRQLILVLEGELYLIPFALLKGSSSNEYLYERFGLLAVP SIRSLSVQSKSHLRKNPPTYSSSTSMAAVIGNPKLPSAVMDRWLWGPMPSAEEEAYMVSELLGCQPLVGSVATKERVMSALTQAECVHFA THISWKLSALVLTPSMDGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPPLQELLLTAADVLDLQLPVKLVVLGSSQESNSKVTAD GVIALTRAFLAAGAQCVLVSLWPVPVAASKMFIHAFYSSLLNGLKASAALGEAMKVVQSSKAFSHPSNWAGFMLIGSDVKLNSPSSLIGQ ALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPPTSGLPAAVFFPTSDPGDRLQQ CSSTLQSLLGLPNPALQALCKLITASETGEQLISRAVKNMVGMLHQVLVQLQAGEKEQDLASAPIQVSISVQLWRLPGCHEFLAALGFDL CEVGQEEVILKTGKQANRRTVHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQQPPFSPTGADSIASDAISVYSLS SIASSMSFVSKPEGGSEGGGPGGRQDHDRSKNAYLQRSTLPRSQLPPQTRPAGNKDEEEYEGFSIISNEPLATYQENRNTCFSPDHKQPQ PGTAGGMRVSVSSKGSISTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEESNPKLDPQELAQKILEETQSHLIA VERLQRSGGQVSKSNNPEDGVQAPSSTAVFRASETSAFSRPVLSHQKSQPSPVTVKPKPPARSSSLPKVSSGYSSPTTSEMSIKDSPSQH SGRPSPGCDSQTSQLDQPLFKLKYPSSPYSAHISKSPRNMSPSSGHQSPAGSAPSPALSYSSAGSARSSPADAPDIDKLKMAAIDEKVQA VHNLKMFWQSTPQHSTGPMKIFRGAPGTMTSKRDVLSLLNLSPRHNKKEEGVDKLELKELSLQQHDGAPPKAPPNGHWRTETTSLGSLPL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_XBP1_ENST00000344347_chr22_29192035_-_TTC28_ENST00000397906_chr22_28559587_-_7086nt ATGGTGGTGGTGGCAGCCGCGCCGAACCCGGCCGACGGGACCCCTAAAGTTCTGCTTCTGTCGGGGCAGCCCGCCTCCGCCGCCGGAGCC CCGGCCGGCCAGGCCCTGCCGCTCATGGTGCCAGCCCAGAGAGGGGCCAGCCCGGAGGCAGCGAGCGGGGGGCTGCCCCAGGCGCGCAAG CGACAGCGCCTCACGCACCTGAGCCCCGAGGAGAAGGCGCTGAGGAGGAAACTGAAAAACAGAGTAGCAGCTCAGACTGCCAGAGATCGA AAGAAGGCTCGAATGAGTGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGAGAACCAAAAACTTTTGCTAGAAAATCAGCTTTTACGA GAGAAAACTCATGGCCTTGTAGTTGAGAACCAGGAGTTAAGACAGCGCTTGGGGATGGATGCCCTGGTTGCTGAAGAGGAGGCGGAAGCC AAGGGGAATGAAGTGAGGCCAGTGGCCGGGTCTGCTGAGTCCGCAGCAGGTGCAGGCCCAGTTGTCACCCCTCCAGAACATCTCCCCATG GATTCTGGCGGTATTGACTCTTCAGATTCAGAGGCAGCTTCATCAGCCTTGAGCAGTCTGGGCCACGTGTACACAGCCATTGGAGACTAC CCCAATGCACTGGCCAGTCACAAACAGTGTGTTCTTCTTGCCAAGCAATCCAAAGATGAACTTTCTGAAGCCCGAGAACTTGGCAACATG GGAGCTGTGTATATTGCCATGGGTGACTTTGAGAATGCTGTGCAGTGCCATGAGCAGCATCTGAAGATAGCCAAGGACCTGGGGAACAAG CGAGAAGAGGCCCGGGCTTATAGCAACCTGGGCAGTGCCTATCACTACCGGAGGAACTTTGACAAGGCCATGTCTTACCATAACTATGTC CTGGAGCTGGCACAGGAGTTGATGGAGAAGGCTATTGAGATGCGGGCCTATGCTGGACTAGGCCATGCTGCCAGGTGCATGCAGGATTTG GAGAGAGCTAAACAATACCATGAGCAGCAGCTGGGCATTGCTGAGGATCTCAAGGACCGGGCTGCAGAGGGGCGAGCATCCTCCAATCTA GGAATCATACACCAGATGAAAGGTGATTATGACACTGCACTGAAACTCCACAAGACCCACCTGTGCATTGCCCAGGAGCTGAGTGATTAT GCTGCCCAGGGCCGTGCCTATGGGAATATGGGCAATGCCTACAATGCCCTGGGCATGTACGACCAGGCGGTCAAATACCATCGGCAGGAG CTGCAGATCTCCATGGAAGTGAATGACCGCGCCTCACAGGCCTCCACACATGGGAACCTTGCCGTGGCCTACCAGGCCCTGGGTGCCCAT GACCGGGCCCTGCAACACTATCAGAACCACTTGAACATCGCCCGGGAGCTACGAGACATCCAGAGCGAGGCCCGGGCCCTCAGCAACCTG GGCAATTTCCACTGCTCTCGGGGAGAGTATGTCCAGGCTGCCCCCTATTATGAACAGTACCTCCGGCTTGCTCCCGACCTTCAAGACATG GAAGGAGAAGGGAAGGTCTGCCACAATCTTGGCTATGCCCATTACTGCCTTGGAAACTATCAGGAGGCAGTGAAGTACTACGAACAGGAT CTGGCACTGGCTAAAGACCTTCACGACAAGTTGAGCCAAGCAAAAGCCTACTGCAACTTGGGCCTAGCATTCAAGGCTCTGCTGAATTTC AGTAAAGCTGAAGAGTGTCAGAAGTACCTACTGTCCCTAGCCCAGTCTCTGAATAATTCCCAGGCTAAATTTCGAGCCCTAGGAAACCTG GGCGATATATTCATCTGTAAAAAAGATATAAATGGTGCAATAAAATTCTATGAGCAGCAACTGGGCTTAGCTCACCAGGTAAAGGACAGA AGATTAGAAGCCAGTGCATATGCAGCCCTGGGCACTGCATACCGAATGATCCAGAAGTATGACAAGGCCCTGGGTTATCACACACAGGAA CTGGAGGTATATCAGGAGCTGAGTGACTTGCCAGGGGAGTGCAGAGCTCATGGGCACCTGGCTGCTGTCTACATGGCCCTTGGGAAATAC ACAATGGCATTCAAGTGTTATGAAGAGCAACTGGATCTAGGGCAAAAGCTGAAGGATCCGAGTCTGGAAGCCCAGGTCTATGGCAACATG GGCATCACAAAGATGAACATGAATGTGATGGAAGAAGCCATTGGCTACTTTGAGCAGCAATTGGCCATGCTGCAGCAGCTAAGTGGAAAT GAGTCTGTGCTCGACAGGGGCCGGGCCTATGGCAACCTGGGGGATTGCTACGAAGCCCTGGGTGACTATGAGGAAGCTATCAAATACTAT GAACAATATTTATCTGTCGCGCAGAGTCTGAATCGCATGCAAGACCAAGCCAAGGCTTACCGGGGCCTGGGAAATGGACACAGGGCAATG GGGAGCTTGCAGCAAGCCCTTGTGTGCTTTGAAAAGAGGCTCGTGGTTGCTCATGAACTTGGAGAGGCCTTCAATAAAGCCCAGGCCTAT GGAGAGCTGGGAAGTCTGCACAGCCAATTAGGGAATTACGAACAAGCCATTTCCTGCCTTGAACGCCAGCTGAACATTGCTAGAGATATG AAAGACCGAGCCCTGGAGAGTGACGCAGCCTGTGGCCTGGGGGGCGTTTACCAGCAGATGGGGGAGTATGACACAGCCCTGCAGTACCAC CAGCTTGATCTACAGATAGCAGAGGAAACCAACAACCCCACGTGCCAGGGCCGAGCCTATGGGAACCTGGGCCTGACTTATGAATCCCTG GGCACCTTCGAGAGGGCTGTGGTCTATCAAGAACAGCACTTGAGCATTGCTGCACAGATGAATGACTTGGCGGCCAAGACGGTGTCATAT AGTAGCCTTGGAAGGACCCATCATGCCTTGCAGAACTATTCCCAAGCAGTCATGTACTTACAGGAAGGTTTAAGGTTAGCTGAGCAACTG GGCCGAAGAGAAGATGAGGCAAAAATTCGCCATGGCCTTGGCCTCTCCCTTTGGGCTAGTGGAAACTTGGAGGAGGCCCAACACCAGCTT TATAGGGCATCAGCCTTGTTTGAAACAATCCGACATGAGGCACAGCTGAGCACGGACTACAAACTCTCCCTCTTTGACCTGCAGACATCA TCCTACCAGGCCTTGCAGCGGGTGCTCGTCAGCCTAGGCCATCATGATGAAGCCCTGGCTGTGGCAGAAAGGGGACGGACAAGGGCATTT GCTGATCTTCTGGTGGAACGACAAACAGGACAACAAGACTCCGACCCCTACTCCCCAGTCACTATTGATCAGATCTTAGAGATGGTAAAT GGCCAGAGGGGACTAGTGCTTTACTATTCCCTGGCTGCAGGCTATCTGTATAGCTGGCTGCTGGCTCCTGGGGCAGGAATTGTGAAGTTT CATGAACACTACCTGGGTGAGAACACAGTGGAAAACTCAAGTGACTTCCAGGCCAGCAGCAGTGTAACCCTTCCAACAGCAACCGGCTCA GCCCTGGAGCAGCACATTGCCAGTGTCCGGGAGGCCCTGGGGGTGGAGTCTCACTACTCAAGGGCCTGTGCCAGCAGTGAGACAGAGAGT GAAGCGGGAGACATCATGGACCAGCAATTTGAAGAGATGAACAACAAACTCAACTCGGTCACTGACCCCACTGGCTTTCTGCGGATGGTT CGCCGCAATAACCTGTTTAACAGGAGCTGCCAGAGCATGACGAGCCTGTTCAGTAACACTGTGTCACCGACCCAGGACGGGACCTCCTCT CTTCCCAGGAGGCAGAGCTCGTTTGCCAAGCCCCCGCTCCGTGCCCTGTATGACCTGCTCATCGCGCCCATGGAAGGGGGCCTGATGCAC TCCAGCGGCCCCGTGGGCCGGCACCGGCAGCTCATCCTGGTTCTGGAGGGGGAGCTCTACCTCATTCCTTTCGCCCTCCTGAAGGGAAGC TCCTCCAATGAGTACCTCTACGAGCGCTTCGGCCTCCTTGCTGTCCCTTCCATCCGCTCCCTCAGCGTGCAGTCCAAGTCTCACTTACGG AAGAACCCGCCCACATACTCCAGCTCCACATCCATGGCGGCTGTCATCGGCAACCCCAAGCTACCATCGGCCGTGATGGACAGGTGGCTG TGGGGGCCCATGCCATCGGCCGAGGAAGAGGCCTACATGGTGTCCGAGCTGCTGGGCTGCCAGCCCCTAGTGGGCAGTGTGGCCACCAAG GAGAGGGTCATGAGTGCCCTGACCCAGGCTGAATGCGTCCACTTTGCCACCCACATCTCCTGGAAGCTGTCGGCCTTGGTCCTCACGCCC AGCATGGACGGCAACCCTGCCAGCAGCAAGAGCTCCTTCGGCCACCCCTACACGATCCCTGAGTCCTTGCGGGTGCAGGACGATGCCAGT GATGGGGAGAGCATCTCGGACTGCCCGCCCCTGCAGGAGCTGCTGCTTACTGCCGCCGACGTCCTGGACCTGCAGCTGCCTGTGAAGCTG GTGGTGCTTGGCTCCTCCCAGGAGTCCAACAGCAAAGTCACAGCCGACGGGGTCATCGCGCTGACAAGGGCCTTCCTGGCTGCCGGCGCT CAGTGTGTCCTCGTGTCTCTGTGGCCTGTGCCAGTGGCTGCTTCTAAGATGTTCATCCATGCCTTCTACTCATCCCTGCTGAACGGCCTG AAAGCCAGCGCCGCCCTGGGGGAGGCCATGAAGGTGGTGCAGAGCAGCAAGGCCTTCTCGCACCCCTCCAACTGGGCAGGGTTCATGCTC ATCGGGAGTGACGTTAAGCTGAACAGCCCCTCATCACTCATCGGCCAGGCCCTCACAGAGATCCTGCAGCACCCGGAGCGTGCGCGGGAC GCCCTGCGAGTGCTGCTGCACCTGGTGGAGAAATCCCTGCAGCGCATCCAGAATGGGCAGCGCAATGCCATGTACACATCCCAGCAGAGT GTGGAGAACAAAGTGGGCGGCATCCCTGGCTGGCAGGCCCTCCTCACCGCTGTGGGCTTCCGGCTGGACCCCCCAACCAGTGGCCTGCCA GCGGCTGTCTTCTTCCCAACCTCCGACCCGGGCGACCGGCTCCAGCAGTGCAGCAGCACACTCCAGTCCCTGCTGGGTCTGCCCAATCCT GCCCTCCAAGCCCTTTGCAAACTCATCACTGCCTCCGAGACGGGCGAGCAGCTCATCAGCCGGGCTGTTAAAAATATGGTTGGAATGCTC CACCAGGTGCTGGTTCAGCTCCAGGCTGGCGAGAAGGAGCAGGACTTGGCATCAGCTCCCATTCAGGTCTCCATCAGCGTCCAGCTGTGG CGGCTCCCGGGATGCCACGAGTTCCTGGCAGCTCTAGGTTTTGATCTCTGTGAAGTTGGTCAGGAGGAAGTAATCCTGAAAACCGGGAAG CAAGCTAATCGACGGACTGTGCACTTCGCGCTCCAGTCCCTGCTGTCTCTGTTTGATTCTACTGAGCTACCCAAGCGCCTCAGCCTTGAC AGCTCCTCCTCCCTCGAGTCTCTTGCTTCTGCTCAGTCTGTTTCCAACGCCCTGCCCTTGGGTTACCAGCAACCCCCCTTCTCTCCCACC GGTGCGGACAGCATCGCCTCAGATGCCATCTCTGTGTACAGTCTGAGCTCCATTGCCTCCTCAATGAGCTTTGTCTCCAAACCCGAGGGT GGATCAGAGGGTGGAGGCCCCGGAGGACGGCAGGACCATGACCGGTCCAAGAACGCTTACCTGCAGAGATCCACCCTGCCTAGGAGCCAG CTGCCTCCCCAGACCCGCCCTGCAGGCAACAAAGATGAAGAAGAATATGAAGGGTTTTCTATCATCAGTAACGAGCCCTTGGCGACCTAC CAAGAAAACCGAAACACATGCTTCTCACCAGACCACAAACAACCCCAACCTGGGACAGCCGGAGGCATGAGAGTCTCGGTGAGCTCCAAA GGGAGCATCAGCACTCCAAATTCTCCAGTGAAAATGACTCTGATTCCCAGCCCCAACTCACCCTTCCAAAAGGTGGGAAAACTAGCAAGC TCAGATACAGGAGAATCAGACCAGTCTAGCACAGAAACGGACAGTACCGTGAAATCCCAAGAAGAAAGCAACCCAAAACTGGATCCACAA GAGTTAGCCCAGAAAATTCTGGAGGAGACACAGAGTCATCTCATTGCGGTGGAGCGTCTTCAGAGGAGCGGCGGCCAGGTGAGCAAGAGT AATAACCCTGAAGACGGCGTTCAGGCGCCCAGCAGCACTGCTGTCTTCAGAGCGTCAGAAACCAGTGCGTTCAGCAGGCCTGTTCTCTCC CATCAGAAGAGTCAGCCATCACCAGTCACTGTTAAACCAAAGCCCCCAGCCAGGAGCTCCTCCCTGCCCAAGGTGAGTTCCGGATATAGC AGCCCCACCACCTCAGAGATGTCCATCAAAGACAGCCCGAGCCAGCACAGTGGCCGGCCATCGCCCGGCTGCGACTCACAGACTTCCCAG CTGGACCAGCCTCTCTTTAAACTGAAGTACCCCAGCTCTCCTTACAGCGCTCACATTTCCAAATCACCAAGGAACATGTCCCCAAGCTCC GGCCACCAGTCTCCTGCTGGCAGTGCACCCTCCCCAGCTCTCTCCTACTCCTCAGCTGGATCTGCTCGCTCAAGTCCAGCAGACGCTCCC GACATAGACAAACTGAAAATGGCAGCCATTGATGAAAAGGTGCAGGCTGTCCATAACCTGAAGATGTTCTGGCAGAGCACACCCCAGCAT TCCACAGGGCCAATGAAGATCTTCCGGGGGGCTCCTGGCACGATGACTTCCAAAAGGGATGTCCTCAGTCTGTTGAATTTGTCACCACGG CACAATAAGAAGGAGGAGGGAGTGGATAAGCTTGAACTGAAGGAGCTGTCCCTGCAGCAGCATGACGGAGCTCCACCGAAAGCCCCTCCC AACGGACACTGGCGCACCGAGACCACCTCGCTGGGCTCACTGCCGCTGCCCGCCGGCCCTCCCGCCACAGCCCCCGCGCGCCCTTTGAGG >In-frame_XBP1_ENST00000216037_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_7668nt ATGGTGGTGGTGGCAGCCGCGCCGAACCCGGCCGACGGGACCCCTAAAGTTCTGCTTCTGTCGGGGCAGCCCGCCTCCGCCGCCGGAGCC CCGGCCGGCCAGGCCCTGCCGCTCATGGTGCCAGCCCAGAGAGGGGCCAGCCCGGAGGCAGCGAGCGGGGGGCTGCCCCAGGCGCGCAAG CGACAGCGCCTCACGCACCTGAGCCCCGAGGAGAAGGCGCTGAGGAGGAAACTGAAAAACAGAGTAGCAGCTCAGACTGCCAGAGATCGA AAGAAGGCTCGAATGAGTGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGAGATTCCTCTCTTTGGTGCTGACACTATTGGCCAGAGA AGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGATTTCCACACA GCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACATGAAAATCCAG CAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGCATACTTCCGACAGGGTGTTGCCCTC CAGTACCTTGGACGTCATGCCGATGCCCTGGCAGCCTTTGCATCTGGACTGGCTCAAGACCCCAAGAGTCTCCAGCTTCTGGTGGGGATG GTGGAAGCCGCCATGAAATCTCCCATGAGAGACTCCCTCGAGCCCACTTATCAGCAGCTTCAGAAAATGAAACTGGACAAGAGTCCCTTT GTGGTCGTGTCTGTGGTTGGGCAGGAACTCCTGACAGCTGGCCATCATGGGGCCTCTGTGGTTGTCTTAGAAGCCGCACTGAAGATTGGC ACCTGCAGCCTCAAACTGAGAGGTTCTGTTTTCTCTGCCCTGAGCAGTGCTTACTGGTCTCTTGGAAATACAGAGAAGAGCACCGGATAT ATGCAGCAGGACTTGGATGTAGCCAAGACCTTAGGTGACCAGACAGGAGAATGCCGAGCTCATGGGAATCTGGGCTCTGCATTCTTCTCC AAAGGAAATTACCGGGAGGCTCTCACTAACCACAGGCATCAGTTGGTACTCGCCATGAAACTCAAAGATCGAGAGGCAGCTTCATCAGCC TTGAGCAGTCTGGGCCACGTGTACACAGCCATTGGAGACTACCCCAATGCACTGGCCAGTCACAAACAGTGTGTTCTTCTTGCCAAGCAA TCCAAAGATGAACTTTCTGAAGCCCGAGAACTTGGCAACATGGGAGCTGTGTATATTGCCATGGGTGACTTTGAGAATGCTGTGCAGTGC CATGAGCAGCATCTGAAGATAGCCAAGGACCTGGGGAACAAGCGAGAAGAGGCCCGGGCTTATAGCAACCTGGGCAGTGCCTATCACTAC CGGAGGAACTTTGACAAGGCCATGTCTTACCATAACTATGTCCTGGAGCTGGCACAGGAGTTGATGGAGAAGGCTATTGAGATGCGGGCC TATGCTGGACTAGGCCATGCTGCCAGGTGCATGCAGGATTTGGAGAGAGCTAAACAATACCATGAGCAGCAGCTGGGCATTGCTGAGGAT CTCAAGGACCGGGCTGCAGAGGGGCGAGCATCCTCCAATCTAGGAATCATACACCAGATGAAAGGTGATTATGACACTGCACTGAAACTC CACAAGACCCACCTGTGCATTGCCCAGGAGCTGAGTGATTATGCTGCCCAGGGCCGTGCCTATGGGAATATGGGCAATGCCTACAATGCC CTGGGCATGTACGACCAGGCGGTCAAATACCATCGGCAGGAGCTGCAGATCTCCATGGAAGTGAATGACCGCGCCTCACAGGCCTCCACA CATGGGAACCTTGCCGTGGCCTACCAGGCCCTGGGTGCCCATGACCGGGCCCTGCAACACTATCAGAACCACTTGAACATCGCCCGGGAG CTACGAGACATCCAGAGCGAGGCCCGGGCCCTCAGCAACCTGGGCAATTTCCACTGCTCTCGGGGAGAGTATGTCCAGGCTGCCCCCTAT TATGAACAGTACCTCCGGCTTGCTCCCGACCTTCAAGACATGGAAGGAGAAGGGAAGGTCTGCCACAATCTTGGCTATGCCCATTACTGC CTTGGAAACTATCAGGAGGCAGTGAAGTACTACGAACAGGATCTGGCACTGGCTAAAGACCTTCACGACAAGTTGAGCCAAGCAAAAGCC TACTGCAACTTGGGCCTAGCATTCAAGGCTCTGCTGAATTTCAGTAAAGCTGAAGAGTGTCAGAAGTACCTACTGTCCCTAGCCCAGTCT CTGAATAATTCCCAGGCTAAATTTCGAGCCCTAGGAAACCTGGGCGATATATTCATCTGTAAAAAAGATATAAATGGTGCAATAAAATTC TATGAGCAGCAACTGGGCTTAGCTCACCAGGTAAAGGACAGAAGATTAGAAGCCAGTGCATATGCAGCCCTGGGCACTGCATACCGAATG ATCCAGAAGTATGACAAGGCCCTGGGTTATCACACACAGGAACTGGAGGTATATCAGGAGCTGAGTGACTTGCCAGGGGAGTGCAGAGCT CATGGGCACCTGGCTGCTGTCTACATGGCCCTTGGGAAATACACAATGGCATTCAAGTGTTATGAAGAGCAACTGGATCTAGGGCAAAAG CTGAAGGATCCGAGTCTGGAAGCCCAGGTCTATGGCAACATGGGCATCACAAAGATGAACATGAATGTGATGGAAGAAGCCATTGGCTAC TTTGAGCAGCAATTGGCCATGCTGCAGCAGCTAAGTGGAAATGAGTCTGTGCTCGACAGGGGCCGGGCCTATGGCAACCTGGGGGATTGC TACGAAGCCCTGGGTGACTATGAGGAAGCTATCAAATACTATGAACAATATTTATCTGTCGCGCAGAGTCTGAATCGCATGCAAGACCAA GCCAAGGCTTACCGGGGCCTGGGAAATGGACACAGGGCAATGGGGAGCTTGCAGCAAGCCCTTGTGTGCTTTGAAAAGAGGCTCGTGGTT GCTCATGAACTTGGAGAGGCCTTCAATAAAGCCCAGGCCTATGGAGAGCTGGGAAGTCTGCACAGCCAATTAGGGAATTACGAACAAGCC ATTTCCTGCCTTGAACGCCAGCTGAACATTGCTAGAGATATGAAAGACCGAGCCCTGGAGAGTGACGCAGCCTGTGGCCTGGGGGGCGTT TACCAGCAGATGGGGGAGTATGACACAGCCCTGCAGTACCACCAGCTTGATCTACAGATAGCAGAGGAAACCAACAACCCCACGTGCCAG GGCCGAGCCTATGGGAACCTGGGCCTGACTTATGAATCCCTGGGCACCTTCGAGAGGGCTGTGGTCTATCAAGAACAGCACTTGAGCATT GCTGCACAGATGAATGACTTGGCGGCCAAGACGGTGTCATATAGTAGCCTTGGAAGGACCCATCATGCCTTGCAGAACTATTCCCAAGCA GTCATGTACTTACAGGAAGGTTTAAGGTTAGCTGAGCAACTGGGCCGAAGAGAAGATGAGGCAAAAATTCGCCATGGCCTTGGCCTCTCC CTTTGGGCTAGTGGAAACTTGGAGGAGGCCCAACACCAGCTTTATAGGGCATCAGCCTTGTTTGAAACAATCCGACATGAGGCACAGCTG AGCACGGACTACAAACTCTCCCTCTTTGACCTGCAGACATCATCCTACCAGGCCTTGCAGCGGGTGCTCGTCAGCCTAGGCCATCATGAT GAAGCCCTGGCTGTGGCAGAAAGGGGACGGACAAGGGCATTTGCTGATCTTCTGGTGGAACGACAAACAGGACAACAAGACTCCGACCCC TACTCCCCAGTCACTATTGATCAGATCTTAGAGATGGTAAATGGCCAGAGGGGACTAGTGCTTTACTATTCCCTGGCTGCAGGCTATCTG TATAGCTGGCTGCTGGCTCCTGGGGCAGGAATTGTGAAGTTTCATGAACACTACCTGGGTGAGAACACAGTGGAAAACTCAAGTGACTTC CAGGCCAGCAGCAGTGTAACCCTTCCAACAGCAACCGGCTCAGCCCTGGAGCAGCACATTGCCAGTGTCCGGGAGGCCCTGGGGGTGGAG TCTCACTACTCAAGGGCCTGTGCCAGCAGTGAGACAGAGAGTGAAGCGGGAGACATCATGGACCAGCAATTTGAAGAGATGAACAACAAA CTCAACTCGGTCACTGACCCCACTGGCTTTCTGCGGATGGTTCGCCGCAATAACCTGTTTAACAGGAGCTGCCAGAGCATGACGAGCCTG TTCAGTAACACTGTGTCACCGACCCAGGACGGGACCTCCTCTCTTCCCAGGAGGCAGAGCTCGTTTGCCAAGCCCCCGCTCCGTGCCCTG TATGACCTGCTCATCGCGCCCATGGAAGGGGGCCTGATGCACTCCAGCGGCCCCGTGGGCCGGCACCGGCAGCTCATCCTGGTTCTGGAG GGGGAGCTCTACCTCATTCCTTTCGCCCTCCTGAAGGGAAGCTCCTCCAATGAGTACCTCTACGAGCGCTTCGGCCTCCTTGCTGTCCCT TCCATCCGCTCCCTCAGCGTGCAGTCCAAGTCTCACTTACGGAAGAACCCGCCCACATACTCCAGCTCCACATCCATGGCGGCTGTCATC GGCAACCCCAAGCTACCATCGGCCGTGATGGACAGGTGGCTGTGGGGGCCCATGCCATCGGCCGAGGAAGAGGCCTACATGGTGTCCGAG CTGCTGGGCTGCCAGCCCCTAGTGGGCAGTGTGGCCACCAAGGAGAGGGTCATGAGTGCCCTGACCCAGGCTGAATGCGTCCACTTTGCC ACCCACATCTCCTGGAAGCTGTCGGCCTTGGTCCTCACGCCCAGCATGGACGGCAACCCTGCCAGCAGCAAGAGCTCCTTCGGCCACCCC TACACGATCCCTGAGTCCTTGCGGGTGCAGGACGATGCCAGTGATGGGGAGAGCATCTCGGACTGCCCGCCCCTGCAGGAGCTGCTGCTT ACTGCCGCCGACGTCCTGGACCTGCAGCTGCCTGTGAAGCTGGTGGTGCTTGGCTCCTCCCAGGAGTCCAACAGCAAAGTCACAGCCGAC GGGGTCATCGCGCTGACAAGGGCCTTCCTGGCTGCCGGCGCTCAGTGTGTCCTCGTGTCTCTGTGGCCTGTGCCAGTGGCTGCTTCTAAG ATGTTCATCCATGCCTTCTACTCATCCCTGCTGAACGGCCTGAAAGCCAGCGCCGCCCTGGGGGAGGCCATGAAGGTGGTGCAGAGCAGC AAGGCCTTCTCGCACCCCTCCAACTGGGCAGGGTTCATGCTCATCGGGAGTGACGTTAAGCTGAACAGCCCCTCATCACTCATCGGCCAG GCCCTCACAGAGATCCTGCAGCACCCGGAGCGTGCGCGGGACGCCCTGCGAGTGCTGCTGCACCTGGTGGAGAAATCCCTGCAGCGCATC CAGAATGGGCAGCGCAATGCCATGTACACATCCCAGCAGAGTGTGGAGAACAAAGTGGGCGGCATCCCTGGCTGGCAGGCCCTCCTCACC GCTGTGGGCTTCCGGCTGGACCCCCCAACCAGTGGCCTGCCAGCGGCTGTCTTCTTCCCAACCTCCGACCCGGGCGACCGGCTCCAGCAG TGCAGCAGCACACTCCAGTCCCTGCTGGGTCTGCCCAATCCTGCCCTCCAAGCCCTTTGCAAACTCATCACTGCCTCCGAGACGGGCGAG CAGCTCATCAGCCGGGCTGTTAAAAATATGGTTGGAATGCTCCACCAGGTGCTGGTTCAGCTCCAGGCTGGCGAGAAGGAGCAGGACTTG GCATCAGCTCCCATTCAGGTCTCCATCAGCGTCCAGCTGTGGCGGCTCCCGGGATGCCACGAGTTCCTGGCAGCTCTAGGTTTTGATCTC TGTGAAGTTGGTCAGGAGGAAGTAATCCTGAAAACCGGGAAGCAAGCTAATCGACGGACTGTGCACTTCGCGCTCCAGTCCCTGCTGTCT CTGTTTGATTCTACTGAGCTACCCAAGCGCCTCAGCCTTGACAGCTCCTCCTCCCTCGAGTCTCTTGCTTCTGCTCAGTCTGTTTCCAAC GCCCTGCCCTTGGGTTACCAGCAACCCCCCTTCTCTCCCACCGGTGCGGACAGCATCGCCTCAGATGCCATCTCTGTGTACAGTCTGAGC TCCATTGCCTCCTCAATGAGCTTTGTCTCCAAACCCGAGGGTGGATCAGAGGGTGGAGGCCCCGGAGGACGGCAGGACCATGACCGGTCC AAGAACGCTTACCTGCAGAGATCCACCCTGCCTAGGAGCCAGCTGCCTCCCCAGACCCGCCCTGCAGGCAACAAAGATGAAGAAGAATAT GAAGGGTTTTCTATCATCAGTAACGAGCCCTTGGCGACCTACCAAGAAAACCGAAACACATGCTTCTCACCAGACCACAAACAACCCCAA CCTGGGACAGCCGGAGGCATGAGAGTCTCGGTGAGCTCCAAAGGGAGCATCAGCACTCCAAATTCTCCAGTGAAAATGACTCTGATTCCC AGCCCCAACTCACCCTTCCAAAAGGTGGGAAAACTAGCAAGCTCAGATACAGGAGAATCAGACCAGTCTAGCACAGAAACGGACAGTACC GTGAAATCCCAAGAAGAAAGCAACCCAAAACTGGATCCACAAGAGTTAGCCCAGAAAATTCTGGAGGAGACACAGAGTCATCTCATTGCG GTGGAGCGTCTTCAGAGGAGCGGCGGCCAGGTGAGCAAGAGTAATAACCCTGAAGACGGCGTTCAGGCGCCCAGCAGCACTGCTGTCTTC AGAGCGTCAGAAACCAGTGCGTTCAGCAGGCCTGTTCTCTCCCATCAGAAGAGTCAGCCATCACCAGTCACTGTTAAACCAAAGCCCCCA GCCAGGAGCTCCTCCCTGCCCAAGGTGAGTTCCGGATATAGCAGCCCCACCACCTCAGAGATGTCCATCAAAGACAGCCCGAGCCAGCAC AGTGGCCGGCCATCGCCCGGCTGCGACTCACAGACTTCCCAGCTGGACCAGCCTCTCTTTAAACTGAAGTACCCCAGCTCTCCTTACAGC GCTCACATTTCCAAATCACCAAGGAACATGTCCCCAAGCTCCGGCCACCAGTCTCCTGCTGGCAGTGCACCCTCCCCAGCTCTCTCCTAC TCCTCAGCTGGATCTGCTCGCTCAAGTCCAGCAGACGCTCCCGACATAGACAAACTGAAAATGGCAGCCATTGATGAAAAGGTGCAGGCT GTCCATAACCTGAAGATGTTCTGGCAGAGCACACCCCAGCATTCCACAGGGCCAATGAAGATCTTCCGGGGGGCTCCTGGCACGATGACT TCCAAAAGGGATGTCCTCAGTCTGTTGAATTTGTCACCACGGCACAATAAGAAGGAGGAGGGAGTGGATAAGCTTGAACTGAAGGAGCTG TCCCTGCAGCAGCATGACGGAGCTCCACCGAAAGCCCCTCCCAACGGACACTGGCGCACCGAGACCACCTCGCTGGGCTCACTGCCGCTG CCCGCCGGCCCTCCCGCCACAGCCCCCGCGCGCCCTTTGAGGCTTCCTTCTGGAAATGGCTACAAGTTCCTGTCTCCAGGAAGATTTTTC >In-frame_XBP1_ENST00000405219_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_7518nt ATGCGGGCACCTGTCTTCCAGGCCCTCTTGCTGTGTGGCCGCAGACTGGTGGTTCAGCCTCTTAACTCGGACATGAGGAAACTGAAAAAC AGAGTAGCAGCTCAGACTGCCAGAGATCGAAAGAAGGCTCGAATGAGTGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGAGATTCCT CTCTTTGGTGCTGACACTATTGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAAT CAGGCCTGTCATGATGGAGATTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGC AATAGATCTGCAGCCTACATGAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCA AAGGCATACTTCCGACAGGGTGTTGCCCTCCAGTACCTTGGACGTCATGCCGATGCCCTGGCAGCCTTTGCATCTGGACTGGCTCAAGAC CCCAAGAGTCTCCAGCTTCTGGTGGGGATGGTGGAAGCCGCCATGAAATCTCCCATGAGAGACTCCCTCGAGCCCACTTATCAGCAGCTT CAGAAAATGAAACTGGACAAGAGTCCCTTTGTGGTCGTGTCTGTGGTTGGGCAGGAACTCCTGACAGCTGGCCATCATGGGGCCTCTGTG GTTGTCTTAGAAGCCGCACTGAAGATTGGCACCTGCAGCCTCAAACTGAGAGGTTCTGTTTTCTCTGCCCTGAGCAGTGCTTACTGGTCT CTTGGAAATACAGAGAAGAGCACCGGATATATGCAGCAGGACTTGGATGTAGCCAAGACCTTAGGTGACCAGACAGGAGAATGCCGAGCT CATGGGAATCTGGGCTCTGCATTCTTCTCCAAAGGAAATTACCGGGAGGCTCTCACTAACCACAGGCATCAGTTGGTACTCGCCATGAAA CTCAAAGATCGAGAGGCAGCTTCATCAGCCTTGAGCAGTCTGGGCCACGTGTACACAGCCATTGGAGACTACCCCAATGCACTGGCCAGT CACAAACAGTGTGTTCTTCTTGCCAAGCAATCCAAAGATGAACTTTCTGAAGCCCGAGAACTTGGCAACATGGGAGCTGTGTATATTGCC ATGGGTGACTTTGAGAATGCTGTGCAGTGCCATGAGCAGCATCTGAAGATAGCCAAGGACCTGGGGAACAAGCGAGAAGAGGCCCGGGCT TATAGCAACCTGGGCAGTGCCTATCACTACCGGAGGAACTTTGACAAGGCCATGTCTTACCATAACTATGTCCTGGAGCTGGCACAGGAG TTGATGGAGAAGGCTATTGAGATGCGGGCCTATGCTGGACTAGGCCATGCTGCCAGGTGCATGCAGGATTTGGAGAGAGCTAAACAATAC CATGAGCAGCAGCTGGGCATTGCTGAGGATCTCAAGGACCGGGCTGCAGAGGGGCGAGCATCCTCCAATCTAGGAATCATACACCAGATG AAAGGTGATTATGACACTGCACTGAAACTCCACAAGACCCACCTGTGCATTGCCCAGGAGCTGAGTGATTATGCTGCCCAGGGCCGTGCC TATGGGAATATGGGCAATGCCTACAATGCCCTGGGCATGTACGACCAGGCGGTCAAATACCATCGGCAGGAGCTGCAGATCTCCATGGAA GTGAATGACCGCGCCTCACAGGCCTCCACACATGGGAACCTTGCCGTGGCCTACCAGGCCCTGGGTGCCCATGACCGGGCCCTGCAACAC TATCAGAACCACTTGAACATCGCCCGGGAGCTACGAGACATCCAGAGCGAGGCCCGGGCCCTCAGCAACCTGGGCAATTTCCACTGCTCT CGGGGAGAGTATGTCCAGGCTGCCCCCTATTATGAACAGTACCTCCGGCTTGCTCCCGACCTTCAAGACATGGAAGGAGAAGGGAAGGTC TGCCACAATCTTGGCTATGCCCATTACTGCCTTGGAAACTATCAGGAGGCAGTGAAGTACTACGAACAGGATCTGGCACTGGCTAAAGAC CTTCACGACAAGTTGAGCCAAGCAAAAGCCTACTGCAACTTGGGCCTAGCATTCAAGGCTCTGCTGAATTTCAGTAAAGCTGAAGAGTGT CAGAAGTACCTACTGTCCCTAGCCCAGTCTCTGAATAATTCCCAGGCTAAATTTCGAGCCCTAGGAAACCTGGGCGATATATTCATCTGT AAAAAAGATATAAATGGTGCAATAAAATTCTATGAGCAGCAACTGGGCTTAGCTCACCAGGTAAAGGACAGAAGATTAGAAGCCAGTGCA TATGCAGCCCTGGGCACTGCATACCGAATGATCCAGAAGTATGACAAGGCCCTGGGTTATCACACACAGGAACTGGAGGTATATCAGGAG CTGAGTGACTTGCCAGGGGAGTGCAGAGCTCATGGGCACCTGGCTGCTGTCTACATGGCCCTTGGGAAATACACAATGGCATTCAAGTGT TATGAAGAGCAACTGGATCTAGGGCAAAAGCTGAAGGATCCGAGTCTGGAAGCCCAGGTCTATGGCAACATGGGCATCACAAAGATGAAC ATGAATGTGATGGAAGAAGCCATTGGCTACTTTGAGCAGCAATTGGCCATGCTGCAGCAGCTAAGTGGAAATGAGTCTGTGCTCGACAGG GGCCGGGCCTATGGCAACCTGGGGGATTGCTACGAAGCCCTGGGTGACTATGAGGAAGCTATCAAATACTATGAACAATATTTATCTGTC GCGCAGAGTCTGAATCGCATGCAAGACCAAGCCAAGGCTTACCGGGGCCTGGGAAATGGACACAGGGCAATGGGGAGCTTGCAGCAAGCC CTTGTGTGCTTTGAAAAGAGGCTCGTGGTTGCTCATGAACTTGGAGAGGCCTTCAATAAAGCCCAGGCCTATGGAGAGCTGGGAAGTCTG CACAGCCAATTAGGGAATTACGAACAAGCCATTTCCTGCCTTGAACGCCAGCTGAACATTGCTAGAGATATGAAAGACCGAGCCCTGGAG AGTGACGCAGCCTGTGGCCTGGGGGGCGTTTACCAGCAGATGGGGGAGTATGACACAGCCCTGCAGTACCACCAGCTTGATCTACAGATA GCAGAGGAAACCAACAACCCCACGTGCCAGGGCCGAGCCTATGGGAACCTGGGCCTGACTTATGAATCCCTGGGCACCTTCGAGAGGGCT GTGGTCTATCAAGAACAGCACTTGAGCATTGCTGCACAGATGAATGACTTGGCGGCCAAGACGGTGTCATATAGTAGCCTTGGAAGGACC CATCATGCCTTGCAGAACTATTCCCAAGCAGTCATGTACTTACAGGAAGGTTTAAGGTTAGCTGAGCAACTGGGCCGAAGAGAAGATGAG GCAAAAATTCGCCATGGCCTTGGCCTCTCCCTTTGGGCTAGTGGAAACTTGGAGGAGGCCCAACACCAGCTTTATAGGGCATCAGCCTTG TTTGAAACAATCCGACATGAGGCACAGCTGAGCACGGACTACAAACTCTCCCTCTTTGACCTGCAGACATCATCCTACCAGGCCTTGCAG CGGGTGCTCGTCAGCCTAGGCCATCATGATGAAGCCCTGGCTGTGGCAGAAAGGGGACGGACAAGGGCATTTGCTGATCTTCTGGTGGAA CGACAAACAGGACAACAAGACTCCGACCCCTACTCCCCAGTCACTATTGATCAGATCTTAGAGATGGTAAATGGCCAGAGGGGACTAGTG CTTTACTATTCCCTGGCTGCAGGCTATCTGTATAGCTGGCTGCTGGCTCCTGGGGCAGGAATTGTGAAGTTTCATGAACACTACCTGGGT GAGAACACAGTGGAAAACTCAAGTGACTTCCAGGCCAGCAGCAGTGTAACCCTTCCAACAGCAACCGGCTCAGCCCTGGAGCAGCACATT GCCAGTGTCCGGGAGGCCCTGGGGGTGGAGTCTCACTACTCAAGGGCCTGTGCCAGCAGTGAGACAGAGAGTGAAGCGGGAGACATCATG GACCAGCAATTTGAAGAGATGAACAACAAACTCAACTCGGTCACTGACCCCACTGGCTTTCTGCGGATGGTTCGCCGCAATAACCTGTTT AACAGGAGCTGCCAGAGCATGACGAGCCTGTTCAGTAACACTGTGTCACCGACCCAGGACGGGACCTCCTCTCTTCCCAGGAGGCAGAGC TCGTTTGCCAAGCCCCCGCTCCGTGCCCTGTATGACCTGCTCATCGCGCCCATGGAAGGGGGCCTGATGCACTCCAGCGGCCCCGTGGGC CGGCACCGGCAGCTCATCCTGGTTCTGGAGGGGGAGCTCTACCTCATTCCTTTCGCCCTCCTGAAGGGAAGCTCCTCCAATGAGTACCTC TACGAGCGCTTCGGCCTCCTTGCTGTCCCTTCCATCCGCTCCCTCAGCGTGCAGTCCAAGTCTCACTTACGGAAGAACCCGCCCACATAC TCCAGCTCCACATCCATGGCGGCTGTCATCGGCAACCCCAAGCTACCATCGGCCGTGATGGACAGGTGGCTGTGGGGGCCCATGCCATCG GCCGAGGAAGAGGCCTACATGGTGTCCGAGCTGCTGGGCTGCCAGCCCCTAGTGGGCAGTGTGGCCACCAAGGAGAGGGTCATGAGTGCC CTGACCCAGGCTGAATGCGTCCACTTTGCCACCCACATCTCCTGGAAGCTGTCGGCCTTGGTCCTCACGCCCAGCATGGACGGCAACCCT GCCAGCAGCAAGAGCTCCTTCGGCCACCCCTACACGATCCCTGAGTCCTTGCGGGTGCAGGACGATGCCAGTGATGGGGAGAGCATCTCG GACTGCCCGCCCCTGCAGGAGCTGCTGCTTACTGCCGCCGACGTCCTGGACCTGCAGCTGCCTGTGAAGCTGGTGGTGCTTGGCTCCTCC CAGGAGTCCAACAGCAAAGTCACAGCCGACGGGGTCATCGCGCTGACAAGGGCCTTCCTGGCTGCCGGCGCTCAGTGTGTCCTCGTGTCT CTGTGGCCTGTGCCAGTGGCTGCTTCTAAGATGTTCATCCATGCCTTCTACTCATCCCTGCTGAACGGCCTGAAAGCCAGCGCCGCCCTG GGGGAGGCCATGAAGGTGGTGCAGAGCAGCAAGGCCTTCTCGCACCCCTCCAACTGGGCAGGGTTCATGCTCATCGGGAGTGACGTTAAG CTGAACAGCCCCTCATCACTCATCGGCCAGGCCCTCACAGAGATCCTGCAGCACCCGGAGCGTGCGCGGGACGCCCTGCGAGTGCTGCTG CACCTGGTGGAGAAATCCCTGCAGCGCATCCAGAATGGGCAGCGCAATGCCATGTACACATCCCAGCAGAGTGTGGAGAACAAAGTGGGC GGCATCCCTGGCTGGCAGGCCCTCCTCACCGCTGTGGGCTTCCGGCTGGACCCCCCAACCAGTGGCCTGCCAGCGGCTGTCTTCTTCCCA ACCTCCGACCCGGGCGACCGGCTCCAGCAGTGCAGCAGCACACTCCAGTCCCTGCTGGGTCTGCCCAATCCTGCCCTCCAAGCCCTTTGC AAACTCATCACTGCCTCCGAGACGGGCGAGCAGCTCATCAGCCGGGCTGTTAAAAATATGGTTGGAATGCTCCACCAGGTGCTGGTTCAG CTCCAGGCTGGCGAGAAGGAGCAGGACTTGGCATCAGCTCCCATTCAGGTCTCCATCAGCGTCCAGCTGTGGCGGCTCCCGGGATGCCAC GAGTTCCTGGCAGCTCTAGGTTTTGATCTCTGTGAAGTTGGTCAGGAGGAAGTAATCCTGAAAACCGGGAAGCAAGCTAATCGACGGACT GTGCACTTCGCGCTCCAGTCCCTGCTGTCTCTGTTTGATTCTACTGAGCTACCCAAGCGCCTCAGCCTTGACAGCTCCTCCTCCCTCGAG TCTCTTGCTTCTGCTCAGTCTGTTTCCAACGCCCTGCCCTTGGGTTACCAGCAACCCCCCTTCTCTCCCACCGGTGCGGACAGCATCGCC TCAGATGCCATCTCTGTGTACAGTCTGAGCTCCATTGCCTCCTCAATGAGCTTTGTCTCCAAACCCGAGGGTGGATCAGAGGGTGGAGGC CCCGGAGGACGGCAGGACCATGACCGGTCCAAGAACGCTTACCTGCAGAGATCCACCCTGCCTAGGAGCCAGCTGCCTCCCCAGACCCGC CCTGCAGGCAACAAAGATGAAGAAGAATATGAAGGGTTTTCTATCATCAGTAACGAGCCCTTGGCGACCTACCAAGAAAACCGAAACACA TGCTTCTCACCAGACCACAAACAACCCCAACCTGGGACAGCCGGAGGCATGAGAGTCTCGGTGAGCTCCAAAGGGAGCATCAGCACTCCA AATTCTCCAGTGAAAATGACTCTGATTCCCAGCCCCAACTCACCCTTCCAAAAGGTGGGAAAACTAGCAAGCTCAGATACAGGAGAATCA GACCAGTCTAGCACAGAAACGGACAGTACCGTGAAATCCCAAGAAGAAAGCAACCCAAAACTGGATCCACAAGAGTTAGCCCAGAAAATT CTGGAGGAGACACAGAGTCATCTCATTGCGGTGGAGCGTCTTCAGAGGAGCGGCGGCCAGGTGAGCAAGAGTAATAACCCTGAAGACGGC GTTCAGGCGCCCAGCAGCACTGCTGTCTTCAGAGCGTCAGAAACCAGTGCGTTCAGCAGGCCTGTTCTCTCCCATCAGAAGAGTCAGCCA TCACCAGTCACTGTTAAACCAAAGCCCCCAGCCAGGAGCTCCTCCCTGCCCAAGGTGAGTTCCGGATATAGCAGCCCCACCACCTCAGAG ATGTCCATCAAAGACAGCCCGAGCCAGCACAGTGGCCGGCCATCGCCCGGCTGCGACTCACAGACTTCCCAGCTGGACCAGCCTCTCTTT AAACTGAAGTACCCCAGCTCTCCTTACAGCGCTCACATTTCCAAATCACCAAGGAACATGTCCCCAAGCTCCGGCCACCAGTCTCCTGCT GGCAGTGCACCCTCCCCAGCTCTCTCCTACTCCTCAGCTGGATCTGCTCGCTCAAGTCCAGCAGACGCTCCCGACATAGACAAACTGAAA ATGGCAGCCATTGATGAAAAGGTGCAGGCTGTCCATAACCTGAAGATGTTCTGGCAGAGCACACCCCAGCATTCCACAGGGCCAATGAAG ATCTTCCGGGGGGCTCCTGGCACGATGACTTCCAAAAGGGATGTCCTCAGTCTGTTGAATTTGTCACCACGGCACAATAAGAAGGAGGAG GGAGTGGATAAGCTTGAACTGAAGGAGCTGTCCCTGCAGCAGCATGACGGAGCTCCACCGAAAGCCCCTCCCAACGGACACTGGCGCACC GAGACCACCTCGCTGGGCTCACTGCCGCTGCCCGCCGGCCCTCCCGCCACAGCCCCCGCGCGCCCTTTGAGGCTTCCTTCTGGAAATGGC >In-frame_XBP1_ENST00000344347_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_7668nt ATGGTGGTGGTGGCAGCCGCGCCGAACCCGGCCGACGGGACCCCTAAAGTTCTGCTTCTGTCGGGGCAGCCCGCCTCCGCCGCCGGAGCC CCGGCCGGCCAGGCCCTGCCGCTCATGGTGCCAGCCCAGAGAGGGGCCAGCCCGGAGGCAGCGAGCGGGGGGCTGCCCCAGGCGCGCAAG CGACAGCGCCTCACGCACCTGAGCCCCGAGGAGAAGGCGCTGAGGAGGAAACTGAAAAACAGAGTAGCAGCTCAGACTGCCAGAGATCGA AAGAAGGCTCGAATGAGTGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGAGATTCCTCTCTTTGGTGCTGACACTATTGGCCAGAGA AGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGATTTCCACACA GCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACATGAAAATCCAG CAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGCATACTTCCGACAGGGTGTTGCCCTC CAGTACCTTGGACGTCATGCCGATGCCCTGGCAGCCTTTGCATCTGGACTGGCTCAAGACCCCAAGAGTCTCCAGCTTCTGGTGGGGATG GTGGAAGCCGCCATGAAATCTCCCATGAGAGACTCCCTCGAGCCCACTTATCAGCAGCTTCAGAAAATGAAACTGGACAAGAGTCCCTTT GTGGTCGTGTCTGTGGTTGGGCAGGAACTCCTGACAGCTGGCCATCATGGGGCCTCTGTGGTTGTCTTAGAAGCCGCACTGAAGATTGGC ACCTGCAGCCTCAAACTGAGAGGTTCTGTTTTCTCTGCCCTGAGCAGTGCTTACTGGTCTCTTGGAAATACAGAGAAGAGCACCGGATAT ATGCAGCAGGACTTGGATGTAGCCAAGACCTTAGGTGACCAGACAGGAGAATGCCGAGCTCATGGGAATCTGGGCTCTGCATTCTTCTCC AAAGGAAATTACCGGGAGGCTCTCACTAACCACAGGCATCAGTTGGTACTCGCCATGAAACTCAAAGATCGAGAGGCAGCTTCATCAGCC TTGAGCAGTCTGGGCCACGTGTACACAGCCATTGGAGACTACCCCAATGCACTGGCCAGTCACAAACAGTGTGTTCTTCTTGCCAAGCAA TCCAAAGATGAACTTTCTGAAGCCCGAGAACTTGGCAACATGGGAGCTGTGTATATTGCCATGGGTGACTTTGAGAATGCTGTGCAGTGC CATGAGCAGCATCTGAAGATAGCCAAGGACCTGGGGAACAAGCGAGAAGAGGCCCGGGCTTATAGCAACCTGGGCAGTGCCTATCACTAC CGGAGGAACTTTGACAAGGCCATGTCTTACCATAACTATGTCCTGGAGCTGGCACAGGAGTTGATGGAGAAGGCTATTGAGATGCGGGCC TATGCTGGACTAGGCCATGCTGCCAGGTGCATGCAGGATTTGGAGAGAGCTAAACAATACCATGAGCAGCAGCTGGGCATTGCTGAGGAT CTCAAGGACCGGGCTGCAGAGGGGCGAGCATCCTCCAATCTAGGAATCATACACCAGATGAAAGGTGATTATGACACTGCACTGAAACTC CACAAGACCCACCTGTGCATTGCCCAGGAGCTGAGTGATTATGCTGCCCAGGGCCGTGCCTATGGGAATATGGGCAATGCCTACAATGCC CTGGGCATGTACGACCAGGCGGTCAAATACCATCGGCAGGAGCTGCAGATCTCCATGGAAGTGAATGACCGCGCCTCACAGGCCTCCACA CATGGGAACCTTGCCGTGGCCTACCAGGCCCTGGGTGCCCATGACCGGGCCCTGCAACACTATCAGAACCACTTGAACATCGCCCGGGAG CTACGAGACATCCAGAGCGAGGCCCGGGCCCTCAGCAACCTGGGCAATTTCCACTGCTCTCGGGGAGAGTATGTCCAGGCTGCCCCCTAT TATGAACAGTACCTCCGGCTTGCTCCCGACCTTCAAGACATGGAAGGAGAAGGGAAGGTCTGCCACAATCTTGGCTATGCCCATTACTGC CTTGGAAACTATCAGGAGGCAGTGAAGTACTACGAACAGGATCTGGCACTGGCTAAAGACCTTCACGACAAGTTGAGCCAAGCAAAAGCC TACTGCAACTTGGGCCTAGCATTCAAGGCTCTGCTGAATTTCAGTAAAGCTGAAGAGTGTCAGAAGTACCTACTGTCCCTAGCCCAGTCT CTGAATAATTCCCAGGCTAAATTTCGAGCCCTAGGAAACCTGGGCGATATATTCATCTGTAAAAAAGATATAAATGGTGCAATAAAATTC TATGAGCAGCAACTGGGCTTAGCTCACCAGGTAAAGGACAGAAGATTAGAAGCCAGTGCATATGCAGCCCTGGGCACTGCATACCGAATG ATCCAGAAGTATGACAAGGCCCTGGGTTATCACACACAGGAACTGGAGGTATATCAGGAGCTGAGTGACTTGCCAGGGGAGTGCAGAGCT CATGGGCACCTGGCTGCTGTCTACATGGCCCTTGGGAAATACACAATGGCATTCAAGTGTTATGAAGAGCAACTGGATCTAGGGCAAAAG CTGAAGGATCCGAGTCTGGAAGCCCAGGTCTATGGCAACATGGGCATCACAAAGATGAACATGAATGTGATGGAAGAAGCCATTGGCTAC TTTGAGCAGCAATTGGCCATGCTGCAGCAGCTAAGTGGAAATGAGTCTGTGCTCGACAGGGGCCGGGCCTATGGCAACCTGGGGGATTGC TACGAAGCCCTGGGTGACTATGAGGAAGCTATCAAATACTATGAACAATATTTATCTGTCGCGCAGAGTCTGAATCGCATGCAAGACCAA GCCAAGGCTTACCGGGGCCTGGGAAATGGACACAGGGCAATGGGGAGCTTGCAGCAAGCCCTTGTGTGCTTTGAAAAGAGGCTCGTGGTT GCTCATGAACTTGGAGAGGCCTTCAATAAAGCCCAGGCCTATGGAGAGCTGGGAAGTCTGCACAGCCAATTAGGGAATTACGAACAAGCC ATTTCCTGCCTTGAACGCCAGCTGAACATTGCTAGAGATATGAAAGACCGAGCCCTGGAGAGTGACGCAGCCTGTGGCCTGGGGGGCGTT TACCAGCAGATGGGGGAGTATGACACAGCCCTGCAGTACCACCAGCTTGATCTACAGATAGCAGAGGAAACCAACAACCCCACGTGCCAG GGCCGAGCCTATGGGAACCTGGGCCTGACTTATGAATCCCTGGGCACCTTCGAGAGGGCTGTGGTCTATCAAGAACAGCACTTGAGCATT GCTGCACAGATGAATGACTTGGCGGCCAAGACGGTGTCATATAGTAGCCTTGGAAGGACCCATCATGCCTTGCAGAACTATTCCCAAGCA GTCATGTACTTACAGGAAGGTTTAAGGTTAGCTGAGCAACTGGGCCGAAGAGAAGATGAGGCAAAAATTCGCCATGGCCTTGGCCTCTCC CTTTGGGCTAGTGGAAACTTGGAGGAGGCCCAACACCAGCTTTATAGGGCATCAGCCTTGTTTGAAACAATCCGACATGAGGCACAGCTG AGCACGGACTACAAACTCTCCCTCTTTGACCTGCAGACATCATCCTACCAGGCCTTGCAGCGGGTGCTCGTCAGCCTAGGCCATCATGAT GAAGCCCTGGCTGTGGCAGAAAGGGGACGGACAAGGGCATTTGCTGATCTTCTGGTGGAACGACAAACAGGACAACAAGACTCCGACCCC TACTCCCCAGTCACTATTGATCAGATCTTAGAGATGGTAAATGGCCAGAGGGGACTAGTGCTTTACTATTCCCTGGCTGCAGGCTATCTG TATAGCTGGCTGCTGGCTCCTGGGGCAGGAATTGTGAAGTTTCATGAACACTACCTGGGTGAGAACACAGTGGAAAACTCAAGTGACTTC CAGGCCAGCAGCAGTGTAACCCTTCCAACAGCAACCGGCTCAGCCCTGGAGCAGCACATTGCCAGTGTCCGGGAGGCCCTGGGGGTGGAG TCTCACTACTCAAGGGCCTGTGCCAGCAGTGAGACAGAGAGTGAAGCGGGAGACATCATGGACCAGCAATTTGAAGAGATGAACAACAAA CTCAACTCGGTCACTGACCCCACTGGCTTTCTGCGGATGGTTCGCCGCAATAACCTGTTTAACAGGAGCTGCCAGAGCATGACGAGCCTG TTCAGTAACACTGTGTCACCGACCCAGGACGGGACCTCCTCTCTTCCCAGGAGGCAGAGCTCGTTTGCCAAGCCCCCGCTCCGTGCCCTG TATGACCTGCTCATCGCGCCCATGGAAGGGGGCCTGATGCACTCCAGCGGCCCCGTGGGCCGGCACCGGCAGCTCATCCTGGTTCTGGAG GGGGAGCTCTACCTCATTCCTTTCGCCCTCCTGAAGGGAAGCTCCTCCAATGAGTACCTCTACGAGCGCTTCGGCCTCCTTGCTGTCCCT TCCATCCGCTCCCTCAGCGTGCAGTCCAAGTCTCACTTACGGAAGAACCCGCCCACATACTCCAGCTCCACATCCATGGCGGCTGTCATC GGCAACCCCAAGCTACCATCGGCCGTGATGGACAGGTGGCTGTGGGGGCCCATGCCATCGGCCGAGGAAGAGGCCTACATGGTGTCCGAG CTGCTGGGCTGCCAGCCCCTAGTGGGCAGTGTGGCCACCAAGGAGAGGGTCATGAGTGCCCTGACCCAGGCTGAATGCGTCCACTTTGCC ACCCACATCTCCTGGAAGCTGTCGGCCTTGGTCCTCACGCCCAGCATGGACGGCAACCCTGCCAGCAGCAAGAGCTCCTTCGGCCACCCC TACACGATCCCTGAGTCCTTGCGGGTGCAGGACGATGCCAGTGATGGGGAGAGCATCTCGGACTGCCCGCCCCTGCAGGAGCTGCTGCTT ACTGCCGCCGACGTCCTGGACCTGCAGCTGCCTGTGAAGCTGGTGGTGCTTGGCTCCTCCCAGGAGTCCAACAGCAAAGTCACAGCCGAC GGGGTCATCGCGCTGACAAGGGCCTTCCTGGCTGCCGGCGCTCAGTGTGTCCTCGTGTCTCTGTGGCCTGTGCCAGTGGCTGCTTCTAAG ATGTTCATCCATGCCTTCTACTCATCCCTGCTGAACGGCCTGAAAGCCAGCGCCGCCCTGGGGGAGGCCATGAAGGTGGTGCAGAGCAGC AAGGCCTTCTCGCACCCCTCCAACTGGGCAGGGTTCATGCTCATCGGGAGTGACGTTAAGCTGAACAGCCCCTCATCACTCATCGGCCAG GCCCTCACAGAGATCCTGCAGCACCCGGAGCGTGCGCGGGACGCCCTGCGAGTGCTGCTGCACCTGGTGGAGAAATCCCTGCAGCGCATC CAGAATGGGCAGCGCAATGCCATGTACACATCCCAGCAGAGTGTGGAGAACAAAGTGGGCGGCATCCCTGGCTGGCAGGCCCTCCTCACC GCTGTGGGCTTCCGGCTGGACCCCCCAACCAGTGGCCTGCCAGCGGCTGTCTTCTTCCCAACCTCCGACCCGGGCGACCGGCTCCAGCAG TGCAGCAGCACACTCCAGTCCCTGCTGGGTCTGCCCAATCCTGCCCTCCAAGCCCTTTGCAAACTCATCACTGCCTCCGAGACGGGCGAG CAGCTCATCAGCCGGGCTGTTAAAAATATGGTTGGAATGCTCCACCAGGTGCTGGTTCAGCTCCAGGCTGGCGAGAAGGAGCAGGACTTG GCATCAGCTCCCATTCAGGTCTCCATCAGCGTCCAGCTGTGGCGGCTCCCGGGATGCCACGAGTTCCTGGCAGCTCTAGGTTTTGATCTC TGTGAAGTTGGTCAGGAGGAAGTAATCCTGAAAACCGGGAAGCAAGCTAATCGACGGACTGTGCACTTCGCGCTCCAGTCCCTGCTGTCT CTGTTTGATTCTACTGAGCTACCCAAGCGCCTCAGCCTTGACAGCTCCTCCTCCCTCGAGTCTCTTGCTTCTGCTCAGTCTGTTTCCAAC GCCCTGCCCTTGGGTTACCAGCAACCCCCCTTCTCTCCCACCGGTGCGGACAGCATCGCCTCAGATGCCATCTCTGTGTACAGTCTGAGC TCCATTGCCTCCTCAATGAGCTTTGTCTCCAAACCCGAGGGTGGATCAGAGGGTGGAGGCCCCGGAGGACGGCAGGACCATGACCGGTCC AAGAACGCTTACCTGCAGAGATCCACCCTGCCTAGGAGCCAGCTGCCTCCCCAGACCCGCCCTGCAGGCAACAAAGATGAAGAAGAATAT GAAGGGTTTTCTATCATCAGTAACGAGCCCTTGGCGACCTACCAAGAAAACCGAAACACATGCTTCTCACCAGACCACAAACAACCCCAA CCTGGGACAGCCGGAGGCATGAGAGTCTCGGTGAGCTCCAAAGGGAGCATCAGCACTCCAAATTCTCCAGTGAAAATGACTCTGATTCCC AGCCCCAACTCACCCTTCCAAAAGGTGGGAAAACTAGCAAGCTCAGATACAGGAGAATCAGACCAGTCTAGCACAGAAACGGACAGTACC GTGAAATCCCAAGAAGAAAGCAACCCAAAACTGGATCCACAAGAGTTAGCCCAGAAAATTCTGGAGGAGACACAGAGTCATCTCATTGCG GTGGAGCGTCTTCAGAGGAGCGGCGGCCAGGTGAGCAAGAGTAATAACCCTGAAGACGGCGTTCAGGCGCCCAGCAGCACTGCTGTCTTC AGAGCGTCAGAAACCAGTGCGTTCAGCAGGCCTGTTCTCTCCCATCAGAAGAGTCAGCCATCACCAGTCACTGTTAAACCAAAGCCCCCA GCCAGGAGCTCCTCCCTGCCCAAGGTGAGTTCCGGATATAGCAGCCCCACCACCTCAGAGATGTCCATCAAAGACAGCCCGAGCCAGCAC AGTGGCCGGCCATCGCCCGGCTGCGACTCACAGACTTCCCAGCTGGACCAGCCTCTCTTTAAACTGAAGTACCCCAGCTCTCCTTACAGC GCTCACATTTCCAAATCACCAAGGAACATGTCCCCAAGCTCCGGCCACCAGTCTCCTGCTGGCAGTGCACCCTCCCCAGCTCTCTCCTAC TCCTCAGCTGGATCTGCTCGCTCAAGTCCAGCAGACGCTCCCGACATAGACAAACTGAAAATGGCAGCCATTGATGAAAAGGTGCAGGCT GTCCATAACCTGAAGATGTTCTGGCAGAGCACACCCCAGCATTCCACAGGGCCAATGAAGATCTTCCGGGGGGCTCCTGGCACGATGACT TCCAAAAGGGATGTCCTCAGTCTGTTGAATTTGTCACCACGGCACAATAAGAAGGAGGAGGGAGTGGATAAGCTTGAACTGAAGGAGCTG TCCCTGCAGCAGCATGACGGAGCTCCACCGAAAGCCCCTCCCAACGGACACTGGCGCACCGAGACCACCTCGCTGGGCTCACTGCCGCTG CCCGCCGGCCCTCCCGCCACAGCCCCCGCGCGCCCTTTGAGGCTTCCTTCTGGAAATGGCTACAAGTTCCTGTCTCCAGGAAGATTTTTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_XBP1_ENST00000344347_chr22_29192035_-_TTC28_ENST00000397906_chr22_28559587_-_11291nt ATGGTGGTGGTGGCAGCCGCGCCGAACCCGGCCGACGGGACCCCTAAAGTTCTGCTTCTGTCGGGGCAGCCCGCCTCCGCCGCCGGAGCC CCGGCCGGCCAGGCCCTGCCGCTCATGGTGCCAGCCCAGAGAGGGGCCAGCCCGGAGGCAGCGAGCGGGGGGCTGCCCCAGGCGCGCAAG CGACAGCGCCTCACGCACCTGAGCCCCGAGGAGAAGGCGCTGAGGAGGAAACTGAAAAACAGAGTAGCAGCTCAGACTGCCAGAGATCGA AAGAAGGCTCGAATGAGTGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGAGAACCAAAAACTTTTGCTAGAAAATCAGCTTTTACGA GAGAAAACTCATGGCCTTGTAGTTGAGAACCAGGAGTTAAGACAGCGCTTGGGGATGGATGCCCTGGTTGCTGAAGAGGAGGCGGAAGCC AAGGGGAATGAAGTGAGGCCAGTGGCCGGGTCTGCTGAGTCCGCAGCAGGTGCAGGCCCAGTTGTCACCCCTCCAGAACATCTCCCCATG GATTCTGGCGGTATTGACTCTTCAGATTCAGAGGCAGCTTCATCAGCCTTGAGCAGTCTGGGCCACGTGTACACAGCCATTGGAGACTAC CCCAATGCACTGGCCAGTCACAAACAGTGTGTTCTTCTTGCCAAGCAATCCAAAGATGAACTTTCTGAAGCCCGAGAACTTGGCAACATG GGAGCTGTGTATATTGCCATGGGTGACTTTGAGAATGCTGTGCAGTGCCATGAGCAGCATCTGAAGATAGCCAAGGACCTGGGGAACAAG CGAGAAGAGGCCCGGGCTTATAGCAACCTGGGCAGTGCCTATCACTACCGGAGGAACTTTGACAAGGCCATGTCTTACCATAACTATGTC CTGGAGCTGGCACAGGAGTTGATGGAGAAGGCTATTGAGATGCGGGCCTATGCTGGACTAGGCCATGCTGCCAGGTGCATGCAGGATTTG GAGAGAGCTAAACAATACCATGAGCAGCAGCTGGGCATTGCTGAGGATCTCAAGGACCGGGCTGCAGAGGGGCGAGCATCCTCCAATCTA GGAATCATACACCAGATGAAAGGTGATTATGACACTGCACTGAAACTCCACAAGACCCACCTGTGCATTGCCCAGGAGCTGAGTGATTAT GCTGCCCAGGGCCGTGCCTATGGGAATATGGGCAATGCCTACAATGCCCTGGGCATGTACGACCAGGCGGTCAAATACCATCGGCAGGAG CTGCAGATCTCCATGGAAGTGAATGACCGCGCCTCACAGGCCTCCACACATGGGAACCTTGCCGTGGCCTACCAGGCCCTGGGTGCCCAT GACCGGGCCCTGCAACACTATCAGAACCACTTGAACATCGCCCGGGAGCTACGAGACATCCAGAGCGAGGCCCGGGCCCTCAGCAACCTG GGCAATTTCCACTGCTCTCGGGGAGAGTATGTCCAGGCTGCCCCCTATTATGAACAGTACCTCCGGCTTGCTCCCGACCTTCAAGACATG GAAGGAGAAGGGAAGGTCTGCCACAATCTTGGCTATGCCCATTACTGCCTTGGAAACTATCAGGAGGCAGTGAAGTACTACGAACAGGAT CTGGCACTGGCTAAAGACCTTCACGACAAGTTGAGCCAAGCAAAAGCCTACTGCAACTTGGGCCTAGCATTCAAGGCTCTGCTGAATTTC AGTAAAGCTGAAGAGTGTCAGAAGTACCTACTGTCCCTAGCCCAGTCTCTGAATAATTCCCAGGCTAAATTTCGAGCCCTAGGAAACCTG GGCGATATATTCATCTGTAAAAAAGATATAAATGGTGCAATAAAATTCTATGAGCAGCAACTGGGCTTAGCTCACCAGGTAAAGGACAGA AGATTAGAAGCCAGTGCATATGCAGCCCTGGGCACTGCATACCGAATGATCCAGAAGTATGACAAGGCCCTGGGTTATCACACACAGGAA CTGGAGGTATATCAGGAGCTGAGTGACTTGCCAGGGGAGTGCAGAGCTCATGGGCACCTGGCTGCTGTCTACATGGCCCTTGGGAAATAC ACAATGGCATTCAAGTGTTATGAAGAGCAACTGGATCTAGGGCAAAAGCTGAAGGATCCGAGTCTGGAAGCCCAGGTCTATGGCAACATG GGCATCACAAAGATGAACATGAATGTGATGGAAGAAGCCATTGGCTACTTTGAGCAGCAATTGGCCATGCTGCAGCAGCTAAGTGGAAAT GAGTCTGTGCTCGACAGGGGCCGGGCCTATGGCAACCTGGGGGATTGCTACGAAGCCCTGGGTGACTATGAGGAAGCTATCAAATACTAT GAACAATATTTATCTGTCGCGCAGAGTCTGAATCGCATGCAAGACCAAGCCAAGGCTTACCGGGGCCTGGGAAATGGACACAGGGCAATG GGGAGCTTGCAGCAAGCCCTTGTGTGCTTTGAAAAGAGGCTCGTGGTTGCTCATGAACTTGGAGAGGCCTTCAATAAAGCCCAGGCCTAT GGAGAGCTGGGAAGTCTGCACAGCCAATTAGGGAATTACGAACAAGCCATTTCCTGCCTTGAACGCCAGCTGAACATTGCTAGAGATATG AAAGACCGAGCCCTGGAGAGTGACGCAGCCTGTGGCCTGGGGGGCGTTTACCAGCAGATGGGGGAGTATGACACAGCCCTGCAGTACCAC CAGCTTGATCTACAGATAGCAGAGGAAACCAACAACCCCACGTGCCAGGGCCGAGCCTATGGGAACCTGGGCCTGACTTATGAATCCCTG GGCACCTTCGAGAGGGCTGTGGTCTATCAAGAACAGCACTTGAGCATTGCTGCACAGATGAATGACTTGGCGGCCAAGACGGTGTCATAT AGTAGCCTTGGAAGGACCCATCATGCCTTGCAGAACTATTCCCAAGCAGTCATGTACTTACAGGAAGGTTTAAGGTTAGCTGAGCAACTG GGCCGAAGAGAAGATGAGGCAAAAATTCGCCATGGCCTTGGCCTCTCCCTTTGGGCTAGTGGAAACTTGGAGGAGGCCCAACACCAGCTT TATAGGGCATCAGCCTTGTTTGAAACAATCCGACATGAGGCACAGCTGAGCACGGACTACAAACTCTCCCTCTTTGACCTGCAGACATCA TCCTACCAGGCCTTGCAGCGGGTGCTCGTCAGCCTAGGCCATCATGATGAAGCCCTGGCTGTGGCAGAAAGGGGACGGACAAGGGCATTT GCTGATCTTCTGGTGGAACGACAAACAGGACAACAAGACTCCGACCCCTACTCCCCAGTCACTATTGATCAGATCTTAGAGATGGTAAAT GGCCAGAGGGGACTAGTGCTTTACTATTCCCTGGCTGCAGGCTATCTGTATAGCTGGCTGCTGGCTCCTGGGGCAGGAATTGTGAAGTTT CATGAACACTACCTGGGTGAGAACACAGTGGAAAACTCAAGTGACTTCCAGGCCAGCAGCAGTGTAACCCTTCCAACAGCAACCGGCTCA GCCCTGGAGCAGCACATTGCCAGTGTCCGGGAGGCCCTGGGGGTGGAGTCTCACTACTCAAGGGCCTGTGCCAGCAGTGAGACAGAGAGT GAAGCGGGAGACATCATGGACCAGCAATTTGAAGAGATGAACAACAAACTCAACTCGGTCACTGACCCCACTGGCTTTCTGCGGATGGTT CGCCGCAATAACCTGTTTAACAGGAGCTGCCAGAGCATGACGAGCCTGTTCAGTAACACTGTGTCACCGACCCAGGACGGGACCTCCTCT CTTCCCAGGAGGCAGAGCTCGTTTGCCAAGCCCCCGCTCCGTGCCCTGTATGACCTGCTCATCGCGCCCATGGAAGGGGGCCTGATGCAC TCCAGCGGCCCCGTGGGCCGGCACCGGCAGCTCATCCTGGTTCTGGAGGGGGAGCTCTACCTCATTCCTTTCGCCCTCCTGAAGGGAAGC TCCTCCAATGAGTACCTCTACGAGCGCTTCGGCCTCCTTGCTGTCCCTTCCATCCGCTCCCTCAGCGTGCAGTCCAAGTCTCACTTACGG AAGAACCCGCCCACATACTCCAGCTCCACATCCATGGCGGCTGTCATCGGCAACCCCAAGCTACCATCGGCCGTGATGGACAGGTGGCTG TGGGGGCCCATGCCATCGGCCGAGGAAGAGGCCTACATGGTGTCCGAGCTGCTGGGCTGCCAGCCCCTAGTGGGCAGTGTGGCCACCAAG GAGAGGGTCATGAGTGCCCTGACCCAGGCTGAATGCGTCCACTTTGCCACCCACATCTCCTGGAAGCTGTCGGCCTTGGTCCTCACGCCC AGCATGGACGGCAACCCTGCCAGCAGCAAGAGCTCCTTCGGCCACCCCTACACGATCCCTGAGTCCTTGCGGGTGCAGGACGATGCCAGT GATGGGGAGAGCATCTCGGACTGCCCGCCCCTGCAGGAGCTGCTGCTTACTGCCGCCGACGTCCTGGACCTGCAGCTGCCTGTGAAGCTG GTGGTGCTTGGCTCCTCCCAGGAGTCCAACAGCAAAGTCACAGCCGACGGGGTCATCGCGCTGACAAGGGCCTTCCTGGCTGCCGGCGCT CAGTGTGTCCTCGTGTCTCTGTGGCCTGTGCCAGTGGCTGCTTCTAAGATGTTCATCCATGCCTTCTACTCATCCCTGCTGAACGGCCTG AAAGCCAGCGCCGCCCTGGGGGAGGCCATGAAGGTGGTGCAGAGCAGCAAGGCCTTCTCGCACCCCTCCAACTGGGCAGGGTTCATGCTC ATCGGGAGTGACGTTAAGCTGAACAGCCCCTCATCACTCATCGGCCAGGCCCTCACAGAGATCCTGCAGCACCCGGAGCGTGCGCGGGAC GCCCTGCGAGTGCTGCTGCACCTGGTGGAGAAATCCCTGCAGCGCATCCAGAATGGGCAGCGCAATGCCATGTACACATCCCAGCAGAGT GTGGAGAACAAAGTGGGCGGCATCCCTGGCTGGCAGGCCCTCCTCACCGCTGTGGGCTTCCGGCTGGACCCCCCAACCAGTGGCCTGCCA GCGGCTGTCTTCTTCCCAACCTCCGACCCGGGCGACCGGCTCCAGCAGTGCAGCAGCACACTCCAGTCCCTGCTGGGTCTGCCCAATCCT GCCCTCCAAGCCCTTTGCAAACTCATCACTGCCTCCGAGACGGGCGAGCAGCTCATCAGCCGGGCTGTTAAAAATATGGTTGGAATGCTC CACCAGGTGCTGGTTCAGCTCCAGGCTGGCGAGAAGGAGCAGGACTTGGCATCAGCTCCCATTCAGGTCTCCATCAGCGTCCAGCTGTGG CGGCTCCCGGGATGCCACGAGTTCCTGGCAGCTCTAGGTTTTGATCTCTGTGAAGTTGGTCAGGAGGAAGTAATCCTGAAAACCGGGAAG CAAGCTAATCGACGGACTGTGCACTTCGCGCTCCAGTCCCTGCTGTCTCTGTTTGATTCTACTGAGCTACCCAAGCGCCTCAGCCTTGAC AGCTCCTCCTCCCTCGAGTCTCTTGCTTCTGCTCAGTCTGTTTCCAACGCCCTGCCCTTGGGTTACCAGCAACCCCCCTTCTCTCCCACC GGTGCGGACAGCATCGCCTCAGATGCCATCTCTGTGTACAGTCTGAGCTCCATTGCCTCCTCAATGAGCTTTGTCTCCAAACCCGAGGGT GGATCAGAGGGTGGAGGCCCCGGAGGACGGCAGGACCATGACCGGTCCAAGAACGCTTACCTGCAGAGATCCACCCTGCCTAGGAGCCAG CTGCCTCCCCAGACCCGCCCTGCAGGCAACAAAGATGAAGAAGAATATGAAGGGTTTTCTATCATCAGTAACGAGCCCTTGGCGACCTAC CAAGAAAACCGAAACACATGCTTCTCACCAGACCACAAACAACCCCAACCTGGGACAGCCGGAGGCATGAGAGTCTCGGTGAGCTCCAAA GGGAGCATCAGCACTCCAAATTCTCCAGTGAAAATGACTCTGATTCCCAGCCCCAACTCACCCTTCCAAAAGGTGGGAAAACTAGCAAGC TCAGATACAGGAGAATCAGACCAGTCTAGCACAGAAACGGACAGTACCGTGAAATCCCAAGAAGAAAGCAACCCAAAACTGGATCCACAA GAGTTAGCCCAGAAAATTCTGGAGGAGACACAGAGTCATCTCATTGCGGTGGAGCGTCTTCAGAGGAGCGGCGGCCAGGTGAGCAAGAGT AATAACCCTGAAGACGGCGTTCAGGCGCCCAGCAGCACTGCTGTCTTCAGAGCGTCAGAAACCAGTGCGTTCAGCAGGCCTGTTCTCTCC CATCAGAAGAGTCAGCCATCACCAGTCACTGTTAAACCAAAGCCCCCAGCCAGGAGCTCCTCCCTGCCCAAGGTGAGTTCCGGATATAGC AGCCCCACCACCTCAGAGATGTCCATCAAAGACAGCCCGAGCCAGCACAGTGGCCGGCCATCGCCCGGCTGCGACTCACAGACTTCCCAG CTGGACCAGCCTCTCTTTAAACTGAAGTACCCCAGCTCTCCTTACAGCGCTCACATTTCCAAATCACCAAGGAACATGTCCCCAAGCTCC GGCCACCAGTCTCCTGCTGGCAGTGCACCCTCCCCAGCTCTCTCCTACTCCTCAGCTGGATCTGCTCGCTCAAGTCCAGCAGACGCTCCC GACATAGACAAACTGAAAATGGCAGCCATTGATGAAAAGGTGCAGGCTGTCCATAACCTGAAGATGTTCTGGCAGAGCACACCCCAGCAT TCCACAGGGCCAATGAAGATCTTCCGGGGGGCTCCTGGCACGATGACTTCCAAAAGGGATGTCCTCAGTCTGTTGAATTTGTCACCACGG CACAATAAGAAGGAGGAGGGAGTGGATAAGCTTGAACTGAAGGAGCTGTCCCTGCAGCAGCATGACGGAGCTCCACCGAAAGCCCCTCCC AACGGACACTGGCGCACCGAGACCACCTCGCTGGGCTCACTGCCGCTGCCCGCCGGCCCTCCCGCCACAGCCCCCGCGCGCCCTTTGAGG CTTCCTTCTGGAAATGGCTACAAGTTCCTGTCTCCAGGAAGATTTTTCCCTTCTTCCAAATGCTAAAGCATCTTTTATACCCACTGACTC TGAGCAGCCTGCAGATGGGGGCCTGGCGTTTGCTTCAGCCCTTCCCTGAGTGCAGTCCCCCCACAGCCACCAGCACCCTCATGATGCTGT GCTCTGCAGGCGAGGGGCACCACCACGTCCAAAGGCTGCCACACACACTGGTGGCTTTTCTGGGCCACATTCACCAAAAGCCAGGACTTC TGTGGGGCTGGTACAGGAGGCTCATGGAATTTCCTACACACTTCACCAAATGTTTGTTTACCTTTGAACTCCCTGCTTCTCATCTTTGAT ATGATTCTTCACCAGGATTTTGTACAAAAATGATCATGGTTCTGGGGTGGGGAGAGGAAAGGGAGCACATATTTTGCTAAGAGGTATATA TGCAGTACCTTTTATACACAGAAATACAAATAGAGCTTTTTCTAAGGCTTTCGGTTGCTGGTTGGGGGTGGGATATATGAAATTTCAGTT GAATTCTACAGGAAAGTGTTATATTAGCCAAAAACAGAAAAATGGTTTTTAAAATGCCAATGATTTGTAATTAAATTGTAGCAATTTTGG TCTCATGATAGTGTAATATCTCAGCAACAATGCAATAATTCACATTGAAACAGCGCTTCCATTCTGAACTCTGCTCTGCAAATGTCTTTT GGGTCCCGCTGTCAACCAAACTTGAATTTTCTTAAAAAAAAAATTATGTAACTCTTATCCAGGCATTTTAGAACTATGCAATTGTGATTT AAAATGCAACTTTGTGCTTTTAAAACATTATTGACCTTTTTTGTATATGGATAAACAACTTGGTTTTATTATCAATAGTACTTTGCATTT ATAGCTATTATTTTTAAAAGCTCAAAAAGTTTTTTAAAATGTCAAATTTTGAATAGTCATCAATAAGTAATTATCAAGTTTGGAAGGAAA GGTTGAAATGACTCCGTTTCCTTATAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTTCCATGGCTAACTAGATTTAAC CAGAATCCCGCCTTCCAGGCTCCTGTTCCCTTTTATTAGCTGCTGAATTTTATTCCCTTTTCCCAACTCCAGGTCCCTCAGTTGTCTTAT ATCTAAATCCTTTGCCAGGTCCCCACAATCCCAGCACCTGCCTCTGTGAGCTGCCCCCAGGCCCTCACCTTGGCCCTGGCCAGCCTCCTG TGCTCCTGCTGTCTGAAGGACTGGCCCCTCCCCCACTGCTGAAGCCACACGTACAGATCCTAAGCAACAGGGCCTTTTGCTGGGACGTAT GCCTGGATTATGGCCAACCGGGAAGAGAGAGATGTATCTTAAAAAGTGGAGGTGGACTTCTCCTACAGCTCTGACGGTAACTTAAATTGT TGCCAGCTTGAGGCAAGACAAGGGAATCATCTAGTTAGGGGTAACCATTAATTTATTTTATAAAGAAAGGAAATGCTGAAAGTCGTATTA GTACTGAGTTTAGTTGGAGAATTTAGATAAGTAAGTATCTTTTAGGTAATTCTAAAATTAAAATCCTACCCACCTCACTACAGGGTTCCT CATGAAGGTGGGCGGCCACCTGGCCTGGGCCACCAGCAGCACATGGAGCAGACCTGAGGGGCCTGGCAGGGGGCACTGACCTCAGGATCC CCAGGTGGGGGTTTTAACCATGGGTGGGATCTCAGCTTCTGCGCATACACTGACAATCTCACCTGTTCCTCAGTGTACTCCTCTGAAAAG AAGAAAGGATAATATTTATCCAATCTGTGTTCTCCTGAGCTCCATCCTAGGGGTTTTTAATTTAACCAACAGCCATGTTGACAAAAGCCA ACAATAAGCATGTCTTATTCTAGCCCTGATCCCAACACTGAAAGCGAAGTACTTTATAAAGAAGCCAGCAATTATGAGGGTTTCTTTATG TTAGTAGGGGAAAAAATGGTAATAAAAGTACCAGTGTAGCAAGTGAAGACCAAATTTATAGCACTGTGCATTAGATAGCAAAATCAGGTT CTTAACAATGAAAAGTAAACCTCAAGTTTCTAAATCCATATGCAGATGGTTAGGCTGTCCCTCTCTTAGCAAATCTCTCAGCCTCCTTCT TTCCCAAGTGCCAAGGATCCCTGGAGTAAAGCTCTGGGGTCTGTGCTCTCTTTCTGTGAGGGGAAGGCTGCGGCCCTATTTGCCCCTCTC TAGCAAACACCCCCACCACCCTGCCGCTTCCTGTGGTTATTGAGCCAGCTAGGAGTTACTCATGGACTCTAACCTGGTTTTAGTCCCATG TACATCGTTGTTTTAGGTTTCATACTGAAGAGCCAATGGTTTATGTGGTTTTATTCTGTCTTAAATATAAGTTTCAAGGAAGGGAAAACA AAAGTGATAAAATGATAGAACAGTCTAGAGGCCACTGTAAAGTCACCGCCACTTTACGTGTATGTCAGTCTTGGTGTTCTTGTATGAGTA AAATGGATGTAAAATCATAAAATCACAGTGAATGTTTCAGGCTACACTGGAAAAAGTATGCACTTAGAATTAAAGGAAATTGTATAATTC ACCAAGATTTCTTTGTGTAGATCAGGGGTTGGCAACTATGACCCACAGGCTAAGACTGGTCAGCGGTCTGGTTTTTCACAGCCATGAGCT AAGTTACCTTTTTAAAGGGTTATATAAGTAATTACATCATATTTTTGATTTTGCCTTTGGCCCACACCACATAAAATATTCAATACCTGG CCTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGATAGAGTGCACTGGTGCGATTTTGGCTCACTGCAACCTCTTCCTC CTGGGTTCAAGCAATTCTCCCTGCCTCAGCCTCTAAGTAGCTGGGACTACAGGCACCCACTACCATGCCTTGCTAATTTTTGTATTTTTA ATAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGGGATCCGCCCGCCTTGGCCTCCCAAACTGCTGGG ATTACAGGTGAGCCACTGCGCCCAGCCAATACCTGGCCTTTTAAGAAGTTTGCTGACTCCTGGTATGGATGACAGAAAATGGAATAACGT TTTGTTTCTCCAGTCTAGGAAAAGCAAGTCAGGTAGTGGATAGACTGACTGGCGTCCGGGGAGCCCAGGGTATGTGAGGGCCACGTGGAT GGAAGCAAATGCCTCCTGCATAGCCCTTGGCTCTTTGTCCCACTTGGGAGGAGTCCATGGATGTAATATTTACAAAACAATTTTTTCCTT ACCATTTGCAGAAAGCATTGCATATATTTCCTTTTAGCTCAGGAAACTGGCATGCCCCACCCTCTGCTACTCCATCAGATGTAAATACAA TGACTATAAGCCGTACAACTCCCCTCTCTTAGAAACCTCAGCAGGACCACAGAGCAAGGGAGTCAAAGCTTTCTTAATTCTCTCCAGTAA ATGACTCAACTAATTTGATTTTTTTAATTAAGTCAAAATATCAAGAGAAAAATTGCTACTAAAACTTACATTTTGATCCACACTGATGTG CAACACAAAATGAAAGTTTTCACCTCCATTCCATTTTTTAAAAATTCACGGTCCACACTGAAACTTGCTGGGTTTTAGCAGGAGACAAAG GTGTCACCCACGCTGTCCTCATCCTGCTCTCTCTGTCCCAGTGACGCTCCAGCATATGATCACTGCAGCCGGTCCCTGGCCCGTGCCGAT TCTGCCACCTCCCAGCCACACACATTTGCAGACCCACAAGAAGAACTGTAGCCTTGATAATTTCAGTTCAGGCTGGAAAAATGCCATGCA ATAATCTGGTTTGCTTTCAGTAAGTAGGCAACAAGTGAAAACTGTATAATTTTCATCACCTATTCTGCTGTTCTATCTAAAATGAGTGTA CCTGTGGTTTGTGAACTGGGCCCTTGTTTGTGCCAGATCCTTCAAAGATGTTCCCTGTCAGGACACCTGTGGCCCTGCCCCTCCTCAGAC ACCTTCCCACTGGCATTCACGTTCCTTATATGCAGTGTTAGCCATCTTTGGCCTACGTGGACTTTTTTTGTAAATTACACCATTTCCAGA CATTAAACTTTTTATATTATGAAATTTACCATGTAAAAAGAACTTCATATTTTTATTGAGATTGCTAAGGCACTTGGCCTTCCTCCTTTG >In-frame_XBP1_ENST00000216037_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_11946nt AGAAAGGCCGGGCGCGGCGAGGCTGGGCGCTGGGCGGCTGCGGCGCGCGGTGCGCGGTGCGTAGTCTGGAGCTATGGTGGTGGTGGCAGC CGCGCCGAACCCGGCCGACGGGACCCCTAAAGTTCTGCTTCTGTCGGGGCAGCCCGCCTCCGCCGCCGGAGCCCCGGCCGGCCAGGCCCT GCCGCTCATGGTGCCAGCCCAGAGAGGGGCCAGCCCGGAGGCAGCGAGCGGGGGGCTGCCCCAGGCGCGCAAGCGACAGCGCCTCACGCA CCTGAGCCCCGAGGAGAAGGCGCTGAGGAGGAAACTGAAAAACAGAGTAGCAGCTCAGACTGCCAGAGATCGAAAGAAGGCTCGAATGAG TGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGAGATTCCTCTCTTTGGTGCTGACACTATTGGCCAGAGAAGTCCTGATGGACCGGT ACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGATTTCCACACAGCTATTGTTCTGTATAA TGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACATGAAAATCCAGCAGTATGACAAGGCACT GGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGCATACTTCCGACAGGGTGTTGCCCTCCAGTACCTTGGACGTCA TGCCGATGCCCTGGCAGCCTTTGCATCTGGACTGGCTCAAGACCCCAAGAGTCTCCAGCTTCTGGTGGGGATGGTGGAAGCCGCCATGAA ATCTCCCATGAGAGACTCCCTCGAGCCCACTTATCAGCAGCTTCAGAAAATGAAACTGGACAAGAGTCCCTTTGTGGTCGTGTCTGTGGT TGGGCAGGAACTCCTGACAGCTGGCCATCATGGGGCCTCTGTGGTTGTCTTAGAAGCCGCACTGAAGATTGGCACCTGCAGCCTCAAACT GAGAGGTTCTGTTTTCTCTGCCCTGAGCAGTGCTTACTGGTCTCTTGGAAATACAGAGAAGAGCACCGGATATATGCAGCAGGACTTGGA TGTAGCCAAGACCTTAGGTGACCAGACAGGAGAATGCCGAGCTCATGGGAATCTGGGCTCTGCATTCTTCTCCAAAGGAAATTACCGGGA GGCTCTCACTAACCACAGGCATCAGTTGGTACTCGCCATGAAACTCAAAGATCGAGAGGCAGCTTCATCAGCCTTGAGCAGTCTGGGCCA CGTGTACACAGCCATTGGAGACTACCCCAATGCACTGGCCAGTCACAAACAGTGTGTTCTTCTTGCCAAGCAATCCAAAGATGAACTTTC TGAAGCCCGAGAACTTGGCAACATGGGAGCTGTGTATATTGCCATGGGTGACTTTGAGAATGCTGTGCAGTGCCATGAGCAGCATCTGAA GATAGCCAAGGACCTGGGGAACAAGCGAGAAGAGGCCCGGGCTTATAGCAACCTGGGCAGTGCCTATCACTACCGGAGGAACTTTGACAA GGCCATGTCTTACCATAACTATGTCCTGGAGCTGGCACAGGAGTTGATGGAGAAGGCTATTGAGATGCGGGCCTATGCTGGACTAGGCCA TGCTGCCAGGTGCATGCAGGATTTGGAGAGAGCTAAACAATACCATGAGCAGCAGCTGGGCATTGCTGAGGATCTCAAGGACCGGGCTGC AGAGGGGCGAGCATCCTCCAATCTAGGAATCATACACCAGATGAAAGGTGATTATGACACTGCACTGAAACTCCACAAGACCCACCTGTG CATTGCCCAGGAGCTGAGTGATTATGCTGCCCAGGGCCGTGCCTATGGGAATATGGGCAATGCCTACAATGCCCTGGGCATGTACGACCA GGCGGTCAAATACCATCGGCAGGAGCTGCAGATCTCCATGGAAGTGAATGACCGCGCCTCACAGGCCTCCACACATGGGAACCTTGCCGT GGCCTACCAGGCCCTGGGTGCCCATGACCGGGCCCTGCAACACTATCAGAACCACTTGAACATCGCCCGGGAGCTACGAGACATCCAGAG CGAGGCCCGGGCCCTCAGCAACCTGGGCAATTTCCACTGCTCTCGGGGAGAGTATGTCCAGGCTGCCCCCTATTATGAACAGTACCTCCG GCTTGCTCCCGACCTTCAAGACATGGAAGGAGAAGGGAAGGTCTGCCACAATCTTGGCTATGCCCATTACTGCCTTGGAAACTATCAGGA GGCAGTGAAGTACTACGAACAGGATCTGGCACTGGCTAAAGACCTTCACGACAAGTTGAGCCAAGCAAAAGCCTACTGCAACTTGGGCCT AGCATTCAAGGCTCTGCTGAATTTCAGTAAAGCTGAAGAGTGTCAGAAGTACCTACTGTCCCTAGCCCAGTCTCTGAATAATTCCCAGGC TAAATTTCGAGCCCTAGGAAACCTGGGCGATATATTCATCTGTAAAAAAGATATAAATGGTGCAATAAAATTCTATGAGCAGCAACTGGG CTTAGCTCACCAGGTAAAGGACAGAAGATTAGAAGCCAGTGCATATGCAGCCCTGGGCACTGCATACCGAATGATCCAGAAGTATGACAA GGCCCTGGGTTATCACACACAGGAACTGGAGGTATATCAGGAGCTGAGTGACTTGCCAGGGGAGTGCAGAGCTCATGGGCACCTGGCTGC TGTCTACATGGCCCTTGGGAAATACACAATGGCATTCAAGTGTTATGAAGAGCAACTGGATCTAGGGCAAAAGCTGAAGGATCCGAGTCT GGAAGCCCAGGTCTATGGCAACATGGGCATCACAAAGATGAACATGAATGTGATGGAAGAAGCCATTGGCTACTTTGAGCAGCAATTGGC CATGCTGCAGCAGCTAAGTGGAAATGAGTCTGTGCTCGACAGGGGCCGGGCCTATGGCAACCTGGGGGATTGCTACGAAGCCCTGGGTGA CTATGAGGAAGCTATCAAATACTATGAACAATATTTATCTGTCGCGCAGAGTCTGAATCGCATGCAAGACCAAGCCAAGGCTTACCGGGG CCTGGGAAATGGACACAGGGCAATGGGGAGCTTGCAGCAAGCCCTTGTGTGCTTTGAAAAGAGGCTCGTGGTTGCTCATGAACTTGGAGA GGCCTTCAATAAAGCCCAGGCCTATGGAGAGCTGGGAAGTCTGCACAGCCAATTAGGGAATTACGAACAAGCCATTTCCTGCCTTGAACG CCAGCTGAACATTGCTAGAGATATGAAAGACCGAGCCCTGGAGAGTGACGCAGCCTGTGGCCTGGGGGGCGTTTACCAGCAGATGGGGGA GTATGACACAGCCCTGCAGTACCACCAGCTTGATCTACAGATAGCAGAGGAAACCAACAACCCCACGTGCCAGGGCCGAGCCTATGGGAA CCTGGGCCTGACTTATGAATCCCTGGGCACCTTCGAGAGGGCTGTGGTCTATCAAGAACAGCACTTGAGCATTGCTGCACAGATGAATGA CTTGGCGGCCAAGACGGTGTCATATAGTAGCCTTGGAAGGACCCATCATGCCTTGCAGAACTATTCCCAAGCAGTCATGTACTTACAGGA AGGTTTAAGGTTAGCTGAGCAACTGGGCCGAAGAGAAGATGAGGCAAAAATTCGCCATGGCCTTGGCCTCTCCCTTTGGGCTAGTGGAAA CTTGGAGGAGGCCCAACACCAGCTTTATAGGGCATCAGCCTTGTTTGAAACAATCCGACATGAGGCACAGCTGAGCACGGACTACAAACT CTCCCTCTTTGACCTGCAGACATCATCCTACCAGGCCTTGCAGCGGGTGCTCGTCAGCCTAGGCCATCATGATGAAGCCCTGGCTGTGGC AGAAAGGGGACGGACAAGGGCATTTGCTGATCTTCTGGTGGAACGACAAACAGGACAACAAGACTCCGACCCCTACTCCCCAGTCACTAT TGATCAGATCTTAGAGATGGTAAATGGCCAGAGGGGACTAGTGCTTTACTATTCCCTGGCTGCAGGCTATCTGTATAGCTGGCTGCTGGC TCCTGGGGCAGGAATTGTGAAGTTTCATGAACACTACCTGGGTGAGAACACAGTGGAAAACTCAAGTGACTTCCAGGCCAGCAGCAGTGT AACCCTTCCAACAGCAACCGGCTCAGCCCTGGAGCAGCACATTGCCAGTGTCCGGGAGGCCCTGGGGGTGGAGTCTCACTACTCAAGGGC CTGTGCCAGCAGTGAGACAGAGAGTGAAGCGGGAGACATCATGGACCAGCAATTTGAAGAGATGAACAACAAACTCAACTCGGTCACTGA CCCCACTGGCTTTCTGCGGATGGTTCGCCGCAATAACCTGTTTAACAGGAGCTGCCAGAGCATGACGAGCCTGTTCAGTAACACTGTGTC ACCGACCCAGGACGGGACCTCCTCTCTTCCCAGGAGGCAGAGCTCGTTTGCCAAGCCCCCGCTCCGTGCCCTGTATGACCTGCTCATCGC GCCCATGGAAGGGGGCCTGATGCACTCCAGCGGCCCCGTGGGCCGGCACCGGCAGCTCATCCTGGTTCTGGAGGGGGAGCTCTACCTCAT TCCTTTCGCCCTCCTGAAGGGAAGCTCCTCCAATGAGTACCTCTACGAGCGCTTCGGCCTCCTTGCTGTCCCTTCCATCCGCTCCCTCAG CGTGCAGTCCAAGTCTCACTTACGGAAGAACCCGCCCACATACTCCAGCTCCACATCCATGGCGGCTGTCATCGGCAACCCCAAGCTACC ATCGGCCGTGATGGACAGGTGGCTGTGGGGGCCCATGCCATCGGCCGAGGAAGAGGCCTACATGGTGTCCGAGCTGCTGGGCTGCCAGCC CCTAGTGGGCAGTGTGGCCACCAAGGAGAGGGTCATGAGTGCCCTGACCCAGGCTGAATGCGTCCACTTTGCCACCCACATCTCCTGGAA GCTGTCGGCCTTGGTCCTCACGCCCAGCATGGACGGCAACCCTGCCAGCAGCAAGAGCTCCTTCGGCCACCCCTACACGATCCCTGAGTC CTTGCGGGTGCAGGACGATGCCAGTGATGGGGAGAGCATCTCGGACTGCCCGCCCCTGCAGGAGCTGCTGCTTACTGCCGCCGACGTCCT GGACCTGCAGCTGCCTGTGAAGCTGGTGGTGCTTGGCTCCTCCCAGGAGTCCAACAGCAAAGTCACAGCCGACGGGGTCATCGCGCTGAC AAGGGCCTTCCTGGCTGCCGGCGCTCAGTGTGTCCTCGTGTCTCTGTGGCCTGTGCCAGTGGCTGCTTCTAAGATGTTCATCCATGCCTT CTACTCATCCCTGCTGAACGGCCTGAAAGCCAGCGCCGCCCTGGGGGAGGCCATGAAGGTGGTGCAGAGCAGCAAGGCCTTCTCGCACCC CTCCAACTGGGCAGGGTTCATGCTCATCGGGAGTGACGTTAAGCTGAACAGCCCCTCATCACTCATCGGCCAGGCCCTCACAGAGATCCT GCAGCACCCGGAGCGTGCGCGGGACGCCCTGCGAGTGCTGCTGCACCTGGTGGAGAAATCCCTGCAGCGCATCCAGAATGGGCAGCGCAA TGCCATGTACACATCCCAGCAGAGTGTGGAGAACAAAGTGGGCGGCATCCCTGGCTGGCAGGCCCTCCTCACCGCTGTGGGCTTCCGGCT GGACCCCCCAACCAGTGGCCTGCCAGCGGCTGTCTTCTTCCCAACCTCCGACCCGGGCGACCGGCTCCAGCAGTGCAGCAGCACACTCCA GTCCCTGCTGGGTCTGCCCAATCCTGCCCTCCAAGCCCTTTGCAAACTCATCACTGCCTCCGAGACGGGCGAGCAGCTCATCAGCCGGGC TGTTAAAAATATGGTTGGAATGCTCCACCAGGTGCTGGTTCAGCTCCAGGCTGGCGAGAAGGAGCAGGACTTGGCATCAGCTCCCATTCA GGTCTCCATCAGCGTCCAGCTGTGGCGGCTCCCGGGATGCCACGAGTTCCTGGCAGCTCTAGGTTTTGATCTCTGTGAAGTTGGTCAGGA GGAAGTAATCCTGAAAACCGGGAAGCAAGCTAATCGACGGACTGTGCACTTCGCGCTCCAGTCCCTGCTGTCTCTGTTTGATTCTACTGA GCTACCCAAGCGCCTCAGCCTTGACAGCTCCTCCTCCCTCGAGTCTCTTGCTTCTGCTCAGTCTGTTTCCAACGCCCTGCCCTTGGGTTA CCAGCAACCCCCCTTCTCTCCCACCGGTGCGGACAGCATCGCCTCAGATGCCATCTCTGTGTACAGTCTGAGCTCCATTGCCTCCTCAAT GAGCTTTGTCTCCAAACCCGAGGGTGGATCAGAGGGTGGAGGCCCCGGAGGACGGCAGGACCATGACCGGTCCAAGAACGCTTACCTGCA GAGATCCACCCTGCCTAGGAGCCAGCTGCCTCCCCAGACCCGCCCTGCAGGCAACAAAGATGAAGAAGAATATGAAGGGTTTTCTATCAT CAGTAACGAGCCCTTGGCGACCTACCAAGAAAACCGAAACACATGCTTCTCACCAGACCACAAACAACCCCAACCTGGGACAGCCGGAGG CATGAGAGTCTCGGTGAGCTCCAAAGGGAGCATCAGCACTCCAAATTCTCCAGTGAAAATGACTCTGATTCCCAGCCCCAACTCACCCTT CCAAAAGGTGGGAAAACTAGCAAGCTCAGATACAGGAGAATCAGACCAGTCTAGCACAGAAACGGACAGTACCGTGAAATCCCAAGAAGA AAGCAACCCAAAACTGGATCCACAAGAGTTAGCCCAGAAAATTCTGGAGGAGACACAGAGTCATCTCATTGCGGTGGAGCGTCTTCAGAG GAGCGGCGGCCAGGTGAGCAAGAGTAATAACCCTGAAGACGGCGTTCAGGCGCCCAGCAGCACTGCTGTCTTCAGAGCGTCAGAAACCAG TGCGTTCAGCAGGCCTGTTCTCTCCCATCAGAAGAGTCAGCCATCACCAGTCACTGTTAAACCAAAGCCCCCAGCCAGGAGCTCCTCCCT GCCCAAGGTGAGTTCCGGATATAGCAGCCCCACCACCTCAGAGATGTCCATCAAAGACAGCCCGAGCCAGCACAGTGGCCGGCCATCGCC CGGCTGCGACTCACAGACTTCCCAGCTGGACCAGCCTCTCTTTAAACTGAAGTACCCCAGCTCTCCTTACAGCGCTCACATTTCCAAATC ACCAAGGAACATGTCCCCAAGCTCCGGCCACCAGTCTCCTGCTGGCAGTGCACCCTCCCCAGCTCTCTCCTACTCCTCAGCTGGATCTGC TCGCTCAAGTCCAGCAGACGCTCCCGACATAGACAAACTGAAAATGGCAGCCATTGATGAAAAGGTGCAGGCTGTCCATAACCTGAAGAT GTTCTGGCAGAGCACACCCCAGCATTCCACAGGGCCAATGAAGATCTTCCGGGGGGCTCCTGGCACGATGACTTCCAAAAGGGATGTCCT CAGTCTGTTGAATTTGTCACCACGGCACAATAAGAAGGAGGAGGGAGTGGATAAGCTTGAACTGAAGGAGCTGTCCCTGCAGCAGCATGA CGGAGCTCCACCGAAAGCCCCTCCCAACGGACACTGGCGCACCGAGACCACCTCGCTGGGCTCACTGCCGCTGCCCGCCGGCCCTCCCGC CACAGCCCCCGCGCGCCCTTTGAGGCTTCCTTCTGGAAATGGCTACAAGTTCCTGTCTCCAGGAAGATTTTTCCCTTCTTCCAAATGCTA AAGCATCTTTTATACCCACTGACTCTGAGCAGCCTGCAGATGGGGGCCTGGCGTTTGCTTCAGCCCTTCCCTGAGTGCAGTCCCCCCACA GCCACCAGCACCCTCATGATGCTGTGCTCTGCAGGCGAGGGGCACCACCACGTCCAAAGGCTGCCACACACACTGGTGGCTTTTCTGGGC CACATTCACCAAAAGCCAGGACTTCTGTGGGGCTGGTACAGGAGGCTCATGGAATTTCCTACACACTTCACCAAATGTTTGTTTACCTTT GAACTCCCTGCTTCTCATCTTTGATATGATTCTTCACCAGGATTTTGTACAAAAATGATCATGGTTCTGGGGTGGGGAGAGGAAAGGGAG CACATATTTTGCTAAGAGGTATATATGCAGTACCTTTTATACACAGAAATACAAATAGAGCTTTTTCTAAGGCTTTCGGTTGCTGGTTGG GGGTGGGATATATGAAATTTCAGTTGAATTCTACAGGAAAGTGTTATATTAGCCAAAAACAGAAAAATGGTTTTTAAAATGCCAATGATT TGTAATTAAATTGTAGCAATTTTGGTCTCATGATAGTGTAATATCTCAGCAACAATGCAATAATTCACATTGAAACAGCGCTTCCATTCT GAACTCTGCTCTGCAAATGTCTTTTGGGTCCCGCTGTCAACCAAACTTGAATTTTCTTAAAAAAAAAATTATGTAACTCTTATCCAGGCA TTTTAGAACTATGCAATTGTGATTTAAAATGCAACTTTGTGCTTTTAAAACATTATTGACCTTTTTTGTATATGGATAAACAACTTGGTT TTATTATCAATAGTACTTTGCATTTATAGCTATTATTTTTAAAAGCTCAAAAAGTTTTTTAAAATGTCAAATTTTGAATAGTCATCAATA AGTAATTATCAAGTTTGGAAGGAAAGGTTGAAATGACTCCGTTTCCTTATAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA ATTTCCATGGCTAACTAGATTTAACCAGAATCCCGCCTTCCAGGCTCCTGTTCCCTTTTATTAGCTGCTGAATTTTATTCCCTTTTCCCA ACTCCAGGTCCCTCAGTTGTCTTATATCTAAATCCTTTGCCAGGTCCCCACAATCCCAGCACCTGCCTCTGTGAGCTGCCCCCAGGCCCT CACCTTGGCCCTGGCCAGCCTCCTGTGCTCCTGCTGTCTGAAGGACTGGCCCCTCCCCCACTGCTGAAGCCACACGTACAGATCCTAAGC AACAGGGCCTTTTGCTGGGACGTATGCCTGGATTATGGCCAACCGGGAAGAGAGAGATGTATCTTAAAAAGTGGAGGTGGACTTCTCCTA CAGCTCTGACGGTAACTTAAATTGTTGCCAGCTTGAGGCAAGACAAGGGAATCATCTAGTTAGGGGTAACCATTAATTTATTTTATAAAG AAAGGAAATGCTGAAAGTCGTATTAGTACTGAGTTTAGTTGGAGAATTTAGATAAGTAAGTATCTTTTAGGTAATTCTAAAATTAAAATC CTACCCACCTCACTACAGGGTTCCTCATGAAGGTGGGCGGCCACCTGGCCTGGGCCACCAGCAGCACATGGAGCAGACCTGAGGGGCCTG GCAGGGGGCACTGACCTCAGGATCCCCAGGTGGGGGTTTTAACCATGGGTGGGATCTCAGCTTCTGCGCATACACTGACAATCTCACCTG TTCCTCAGTGTACTCCTCTGAAAAGAAGAAAGGATAATATTTATCCAATCTGTGTTCTCCTGAGCTCCATCCTAGGGGTTTTTAATTTAA CCAACAGCCATGTTGACAAAAGCCAACAATAAGCATGTCTTATTCTAGCCCTGATCCCAACACTGAAAGCGAAGTACTTTATAAAGAAGC CAGCAATTATGAGGGTTTCTTTATGTTAGTAGGGGAAAAAATGGTAATAAAAGTACCAGTGTAGCAAGTGAAGACCAAATTTATAGCACT GTGCATTAGATAGCAAAATCAGGTTCTTAACAATGAAAAGTAAACCTCAAGTTTCTAAATCCATATGCAGATGGTTAGGCTGTCCCTCTC TTAGCAAATCTCTCAGCCTCCTTCTTTCCCAAGTGCCAAGGATCCCTGGAGTAAAGCTCTGGGGTCTGTGCTCTCTTTCTGTGAGGGGAA GGCTGCGGCCCTATTTGCCCCTCTCTAGCAAACACCCCCACCACCCTGCCGCTTCCTGTGGTTATTGAGCCAGCTAGGAGTTACTCATGG ACTCTAACCTGGTTTTAGTCCCATGTACATCGTTGTTTTAGGTTTCATACTGAAGAGCCAATGGTTTATGTGGTTTTATTCTGTCTTAAA TATAAGTTTCAAGGAAGGGAAAACAAAAGTGATAAAATGATAGAACAGTCTAGAGGCCACTGTAAAGTCACCGCCACTTTACGTGTATGT CAGTCTTGGTGTTCTTGTATGAGTAAAATGGATGTAAAATCATAAAATCACAGTGAATGTTTCAGGCTACACTGGAAAAAGTATGCACTT AGAATTAAAGGAAATTGTATAATTCACCAAGATTTCTTTGTGTAGATCAGGGGTTGGCAACTATGACCCACAGGCTAAGACTGGTCAGCG GTCTGGTTTTTCACAGCCATGAGCTAAGTTACCTTTTTAAAGGGTTATATAAGTAATTACATCATATTTTTGATTTTGCCTTTGGCCCAC ACCACATAAAATATTCAATACCTGGCCTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGATAGAGTGCACTGGTGCGAT TTTGGCTCACTGCAACCTCTTCCTCCTGGGTTCAAGCAATTCTCCCTGCCTCAGCCTCTAAGTAGCTGGGACTACAGGCACCCACTACCA TGCCTTGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGGGATCCGCC CGCCTTGGCCTCCCAAACTGCTGGGATTACAGGTGAGCCACTGCGCCCAGCCAATACCTGGCCTTTTAAGAAGTTTGCTGACTCCTGGTA TGGATGACAGAAAATGGAATAACGTTTTGTTTCTCCAGTCTAGGAAAAGCAAGTCAGGTAGTGGATAGACTGACTGGCGTCCGGGGAGCC CAGGGTATGTGAGGGCCACGTGGATGGAAGCAAATGCCTCCTGCATAGCCCTTGGCTCTTTGTCCCACTTGGGAGGAGTCCATGGATGTA ATATTTACAAAACAATTTTTTCCTTACCATTTGCAGAAAGCATTGCATATATTTCCTTTTAGCTCAGGAAACTGGCATGCCCCACCCTCT GCTACTCCATCAGATGTAAATACAATGACTATAAGCCGTACAACTCCCCTCTCTTAGAAACCTCAGCAGGACCACAGAGCAAGGGAGTCA AAGCTTTCTTAATTCTCTCCAGTAAATGACTCAACTAATTTGATTTTTTTAATTAAGTCAAAATATCAAGAGAAAAATTGCTACTAAAAC TTACATTTTGATCCACACTGATGTGCAACACAAAATGAAAGTTTTCACCTCCATTCCATTTTTTAAAAATTCACGGTCCACACTGAAACT TGCTGGGTTTTAGCAGGAGACAAAGGTGTCACCCACGCTGTCCTCATCCTGCTCTCTCTGTCCCAGTGACGCTCCAGCATATGATCACTG CAGCCGGTCCCTGGCCCGTGCCGATTCTGCCACCTCCCAGCCACACACATTTGCAGACCCACAAGAAGAACTGTAGCCTTGATAATTTCA GTTCAGGCTGGAAAAATGCCATGCAATAATCTGGTTTGCTTTCAGTAAGTAGGCAACAAGTGAAAACTGTATAATTTTCATCACCTATTC TGCTGTTCTATCTAAAATGAGTGTACCTGTGGTTTGTGAACTGGGCCCTTGTTTGTGCCAGATCCTTCAAAGATGTTCCCTGTCAGGACA CCTGTGGCCCTGCCCCTCCTCAGACACCTTCCCACTGGCATTCACGTTCCTTATATGCAGTGTTAGCCATCTTTGGCCTACGTGGACTTT TTTTGTAAATTACACCATTTCCAGACATTAAACTTTTTATATTATGAAATTTACCATGTAAAAAGAACTTCATATTTTTATTGAGATTGC >In-frame_XBP1_ENST00000405219_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_11820nt CCGGACTGACCGGATCCGCCACGCTGGGAACCTAGGGCGGCCCAGGGCTCTTTTCTGTACTTTTTAACTCTCTCGTTAGAGATGACCAGA GCTGGGGATGCGGGCACCTGTCTTCCAGGCCCTCTTGCTGTGTGGCCGCAGACTGGTGGTTCAGCCTCTTAACTCGGACATGAGGAAACT GAAAAACAGAGTAGCAGCTCAGACTGCCAGAGATCGAAAGAAGGCTCGAATGAGTGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGA GATTCCTCTCTTTGGTGCTGACACTATTGGCCAGAGAAGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCA GAGTAATCAGGCCTGTCATGATGGAGATTTCCACACAGCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTT ATACAGCAATAGATCTGCAGCCTACATGAAAATCCAGCAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAA GTGGCCAAAGGCATACTTCCGACAGGGTGTTGCCCTCCAGTACCTTGGACGTCATGCCGATGCCCTGGCAGCCTTTGCATCTGGACTGGC TCAAGACCCCAAGAGTCTCCAGCTTCTGGTGGGGATGGTGGAAGCCGCCATGAAATCTCCCATGAGAGACTCCCTCGAGCCCACTTATCA GCAGCTTCAGAAAATGAAACTGGACAAGAGTCCCTTTGTGGTCGTGTCTGTGGTTGGGCAGGAACTCCTGACAGCTGGCCATCATGGGGC CTCTGTGGTTGTCTTAGAAGCCGCACTGAAGATTGGCACCTGCAGCCTCAAACTGAGAGGTTCTGTTTTCTCTGCCCTGAGCAGTGCTTA CTGGTCTCTTGGAAATACAGAGAAGAGCACCGGATATATGCAGCAGGACTTGGATGTAGCCAAGACCTTAGGTGACCAGACAGGAGAATG CCGAGCTCATGGGAATCTGGGCTCTGCATTCTTCTCCAAAGGAAATTACCGGGAGGCTCTCACTAACCACAGGCATCAGTTGGTACTCGC CATGAAACTCAAAGATCGAGAGGCAGCTTCATCAGCCTTGAGCAGTCTGGGCCACGTGTACACAGCCATTGGAGACTACCCCAATGCACT GGCCAGTCACAAACAGTGTGTTCTTCTTGCCAAGCAATCCAAAGATGAACTTTCTGAAGCCCGAGAACTTGGCAACATGGGAGCTGTGTA TATTGCCATGGGTGACTTTGAGAATGCTGTGCAGTGCCATGAGCAGCATCTGAAGATAGCCAAGGACCTGGGGAACAAGCGAGAAGAGGC CCGGGCTTATAGCAACCTGGGCAGTGCCTATCACTACCGGAGGAACTTTGACAAGGCCATGTCTTACCATAACTATGTCCTGGAGCTGGC ACAGGAGTTGATGGAGAAGGCTATTGAGATGCGGGCCTATGCTGGACTAGGCCATGCTGCCAGGTGCATGCAGGATTTGGAGAGAGCTAA ACAATACCATGAGCAGCAGCTGGGCATTGCTGAGGATCTCAAGGACCGGGCTGCAGAGGGGCGAGCATCCTCCAATCTAGGAATCATACA CCAGATGAAAGGTGATTATGACACTGCACTGAAACTCCACAAGACCCACCTGTGCATTGCCCAGGAGCTGAGTGATTATGCTGCCCAGGG CCGTGCCTATGGGAATATGGGCAATGCCTACAATGCCCTGGGCATGTACGACCAGGCGGTCAAATACCATCGGCAGGAGCTGCAGATCTC CATGGAAGTGAATGACCGCGCCTCACAGGCCTCCACACATGGGAACCTTGCCGTGGCCTACCAGGCCCTGGGTGCCCATGACCGGGCCCT GCAACACTATCAGAACCACTTGAACATCGCCCGGGAGCTACGAGACATCCAGAGCGAGGCCCGGGCCCTCAGCAACCTGGGCAATTTCCA CTGCTCTCGGGGAGAGTATGTCCAGGCTGCCCCCTATTATGAACAGTACCTCCGGCTTGCTCCCGACCTTCAAGACATGGAAGGAGAAGG GAAGGTCTGCCACAATCTTGGCTATGCCCATTACTGCCTTGGAAACTATCAGGAGGCAGTGAAGTACTACGAACAGGATCTGGCACTGGC TAAAGACCTTCACGACAAGTTGAGCCAAGCAAAAGCCTACTGCAACTTGGGCCTAGCATTCAAGGCTCTGCTGAATTTCAGTAAAGCTGA AGAGTGTCAGAAGTACCTACTGTCCCTAGCCCAGTCTCTGAATAATTCCCAGGCTAAATTTCGAGCCCTAGGAAACCTGGGCGATATATT CATCTGTAAAAAAGATATAAATGGTGCAATAAAATTCTATGAGCAGCAACTGGGCTTAGCTCACCAGGTAAAGGACAGAAGATTAGAAGC CAGTGCATATGCAGCCCTGGGCACTGCATACCGAATGATCCAGAAGTATGACAAGGCCCTGGGTTATCACACACAGGAACTGGAGGTATA TCAGGAGCTGAGTGACTTGCCAGGGGAGTGCAGAGCTCATGGGCACCTGGCTGCTGTCTACATGGCCCTTGGGAAATACACAATGGCATT CAAGTGTTATGAAGAGCAACTGGATCTAGGGCAAAAGCTGAAGGATCCGAGTCTGGAAGCCCAGGTCTATGGCAACATGGGCATCACAAA GATGAACATGAATGTGATGGAAGAAGCCATTGGCTACTTTGAGCAGCAATTGGCCATGCTGCAGCAGCTAAGTGGAAATGAGTCTGTGCT CGACAGGGGCCGGGCCTATGGCAACCTGGGGGATTGCTACGAAGCCCTGGGTGACTATGAGGAAGCTATCAAATACTATGAACAATATTT ATCTGTCGCGCAGAGTCTGAATCGCATGCAAGACCAAGCCAAGGCTTACCGGGGCCTGGGAAATGGACACAGGGCAATGGGGAGCTTGCA GCAAGCCCTTGTGTGCTTTGAAAAGAGGCTCGTGGTTGCTCATGAACTTGGAGAGGCCTTCAATAAAGCCCAGGCCTATGGAGAGCTGGG AAGTCTGCACAGCCAATTAGGGAATTACGAACAAGCCATTTCCTGCCTTGAACGCCAGCTGAACATTGCTAGAGATATGAAAGACCGAGC CCTGGAGAGTGACGCAGCCTGTGGCCTGGGGGGCGTTTACCAGCAGATGGGGGAGTATGACACAGCCCTGCAGTACCACCAGCTTGATCT ACAGATAGCAGAGGAAACCAACAACCCCACGTGCCAGGGCCGAGCCTATGGGAACCTGGGCCTGACTTATGAATCCCTGGGCACCTTCGA GAGGGCTGTGGTCTATCAAGAACAGCACTTGAGCATTGCTGCACAGATGAATGACTTGGCGGCCAAGACGGTGTCATATAGTAGCCTTGG AAGGACCCATCATGCCTTGCAGAACTATTCCCAAGCAGTCATGTACTTACAGGAAGGTTTAAGGTTAGCTGAGCAACTGGGCCGAAGAGA AGATGAGGCAAAAATTCGCCATGGCCTTGGCCTCTCCCTTTGGGCTAGTGGAAACTTGGAGGAGGCCCAACACCAGCTTTATAGGGCATC AGCCTTGTTTGAAACAATCCGACATGAGGCACAGCTGAGCACGGACTACAAACTCTCCCTCTTTGACCTGCAGACATCATCCTACCAGGC CTTGCAGCGGGTGCTCGTCAGCCTAGGCCATCATGATGAAGCCCTGGCTGTGGCAGAAAGGGGACGGACAAGGGCATTTGCTGATCTTCT GGTGGAACGACAAACAGGACAACAAGACTCCGACCCCTACTCCCCAGTCACTATTGATCAGATCTTAGAGATGGTAAATGGCCAGAGGGG ACTAGTGCTTTACTATTCCCTGGCTGCAGGCTATCTGTATAGCTGGCTGCTGGCTCCTGGGGCAGGAATTGTGAAGTTTCATGAACACTA CCTGGGTGAGAACACAGTGGAAAACTCAAGTGACTTCCAGGCCAGCAGCAGTGTAACCCTTCCAACAGCAACCGGCTCAGCCCTGGAGCA GCACATTGCCAGTGTCCGGGAGGCCCTGGGGGTGGAGTCTCACTACTCAAGGGCCTGTGCCAGCAGTGAGACAGAGAGTGAAGCGGGAGA CATCATGGACCAGCAATTTGAAGAGATGAACAACAAACTCAACTCGGTCACTGACCCCACTGGCTTTCTGCGGATGGTTCGCCGCAATAA CCTGTTTAACAGGAGCTGCCAGAGCATGACGAGCCTGTTCAGTAACACTGTGTCACCGACCCAGGACGGGACCTCCTCTCTTCCCAGGAG GCAGAGCTCGTTTGCCAAGCCCCCGCTCCGTGCCCTGTATGACCTGCTCATCGCGCCCATGGAAGGGGGCCTGATGCACTCCAGCGGCCC CGTGGGCCGGCACCGGCAGCTCATCCTGGTTCTGGAGGGGGAGCTCTACCTCATTCCTTTCGCCCTCCTGAAGGGAAGCTCCTCCAATGA GTACCTCTACGAGCGCTTCGGCCTCCTTGCTGTCCCTTCCATCCGCTCCCTCAGCGTGCAGTCCAAGTCTCACTTACGGAAGAACCCGCC CACATACTCCAGCTCCACATCCATGGCGGCTGTCATCGGCAACCCCAAGCTACCATCGGCCGTGATGGACAGGTGGCTGTGGGGGCCCAT GCCATCGGCCGAGGAAGAGGCCTACATGGTGTCCGAGCTGCTGGGCTGCCAGCCCCTAGTGGGCAGTGTGGCCACCAAGGAGAGGGTCAT GAGTGCCCTGACCCAGGCTGAATGCGTCCACTTTGCCACCCACATCTCCTGGAAGCTGTCGGCCTTGGTCCTCACGCCCAGCATGGACGG CAACCCTGCCAGCAGCAAGAGCTCCTTCGGCCACCCCTACACGATCCCTGAGTCCTTGCGGGTGCAGGACGATGCCAGTGATGGGGAGAG CATCTCGGACTGCCCGCCCCTGCAGGAGCTGCTGCTTACTGCCGCCGACGTCCTGGACCTGCAGCTGCCTGTGAAGCTGGTGGTGCTTGG CTCCTCCCAGGAGTCCAACAGCAAAGTCACAGCCGACGGGGTCATCGCGCTGACAAGGGCCTTCCTGGCTGCCGGCGCTCAGTGTGTCCT CGTGTCTCTGTGGCCTGTGCCAGTGGCTGCTTCTAAGATGTTCATCCATGCCTTCTACTCATCCCTGCTGAACGGCCTGAAAGCCAGCGC CGCCCTGGGGGAGGCCATGAAGGTGGTGCAGAGCAGCAAGGCCTTCTCGCACCCCTCCAACTGGGCAGGGTTCATGCTCATCGGGAGTGA CGTTAAGCTGAACAGCCCCTCATCACTCATCGGCCAGGCCCTCACAGAGATCCTGCAGCACCCGGAGCGTGCGCGGGACGCCCTGCGAGT GCTGCTGCACCTGGTGGAGAAATCCCTGCAGCGCATCCAGAATGGGCAGCGCAATGCCATGTACACATCCCAGCAGAGTGTGGAGAACAA AGTGGGCGGCATCCCTGGCTGGCAGGCCCTCCTCACCGCTGTGGGCTTCCGGCTGGACCCCCCAACCAGTGGCCTGCCAGCGGCTGTCTT CTTCCCAACCTCCGACCCGGGCGACCGGCTCCAGCAGTGCAGCAGCACACTCCAGTCCCTGCTGGGTCTGCCCAATCCTGCCCTCCAAGC CCTTTGCAAACTCATCACTGCCTCCGAGACGGGCGAGCAGCTCATCAGCCGGGCTGTTAAAAATATGGTTGGAATGCTCCACCAGGTGCT GGTTCAGCTCCAGGCTGGCGAGAAGGAGCAGGACTTGGCATCAGCTCCCATTCAGGTCTCCATCAGCGTCCAGCTGTGGCGGCTCCCGGG ATGCCACGAGTTCCTGGCAGCTCTAGGTTTTGATCTCTGTGAAGTTGGTCAGGAGGAAGTAATCCTGAAAACCGGGAAGCAAGCTAATCG ACGGACTGTGCACTTCGCGCTCCAGTCCCTGCTGTCTCTGTTTGATTCTACTGAGCTACCCAAGCGCCTCAGCCTTGACAGCTCCTCCTC CCTCGAGTCTCTTGCTTCTGCTCAGTCTGTTTCCAACGCCCTGCCCTTGGGTTACCAGCAACCCCCCTTCTCTCCCACCGGTGCGGACAG CATCGCCTCAGATGCCATCTCTGTGTACAGTCTGAGCTCCATTGCCTCCTCAATGAGCTTTGTCTCCAAACCCGAGGGTGGATCAGAGGG TGGAGGCCCCGGAGGACGGCAGGACCATGACCGGTCCAAGAACGCTTACCTGCAGAGATCCACCCTGCCTAGGAGCCAGCTGCCTCCCCA GACCCGCCCTGCAGGCAACAAAGATGAAGAAGAATATGAAGGGTTTTCTATCATCAGTAACGAGCCCTTGGCGACCTACCAAGAAAACCG AAACACATGCTTCTCACCAGACCACAAACAACCCCAACCTGGGACAGCCGGAGGCATGAGAGTCTCGGTGAGCTCCAAAGGGAGCATCAG CACTCCAAATTCTCCAGTGAAAATGACTCTGATTCCCAGCCCCAACTCACCCTTCCAAAAGGTGGGAAAACTAGCAAGCTCAGATACAGG AGAATCAGACCAGTCTAGCACAGAAACGGACAGTACCGTGAAATCCCAAGAAGAAAGCAACCCAAAACTGGATCCACAAGAGTTAGCCCA GAAAATTCTGGAGGAGACACAGAGTCATCTCATTGCGGTGGAGCGTCTTCAGAGGAGCGGCGGCCAGGTGAGCAAGAGTAATAACCCTGA AGACGGCGTTCAGGCGCCCAGCAGCACTGCTGTCTTCAGAGCGTCAGAAACCAGTGCGTTCAGCAGGCCTGTTCTCTCCCATCAGAAGAG TCAGCCATCACCAGTCACTGTTAAACCAAAGCCCCCAGCCAGGAGCTCCTCCCTGCCCAAGGTGAGTTCCGGATATAGCAGCCCCACCAC CTCAGAGATGTCCATCAAAGACAGCCCGAGCCAGCACAGTGGCCGGCCATCGCCCGGCTGCGACTCACAGACTTCCCAGCTGGACCAGCC TCTCTTTAAACTGAAGTACCCCAGCTCTCCTTACAGCGCTCACATTTCCAAATCACCAAGGAACATGTCCCCAAGCTCCGGCCACCAGTC TCCTGCTGGCAGTGCACCCTCCCCAGCTCTCTCCTACTCCTCAGCTGGATCTGCTCGCTCAAGTCCAGCAGACGCTCCCGACATAGACAA ACTGAAAATGGCAGCCATTGATGAAAAGGTGCAGGCTGTCCATAACCTGAAGATGTTCTGGCAGAGCACACCCCAGCATTCCACAGGGCC AATGAAGATCTTCCGGGGGGCTCCTGGCACGATGACTTCCAAAAGGGATGTCCTCAGTCTGTTGAATTTGTCACCACGGCACAATAAGAA GGAGGAGGGAGTGGATAAGCTTGAACTGAAGGAGCTGTCCCTGCAGCAGCATGACGGAGCTCCACCGAAAGCCCCTCCCAACGGACACTG GCGCACCGAGACCACCTCGCTGGGCTCACTGCCGCTGCCCGCCGGCCCTCCCGCCACAGCCCCCGCGCGCCCTTTGAGGCTTCCTTCTGG AAATGGCTACAAGTTCCTGTCTCCAGGAAGATTTTTCCCTTCTTCCAAATGCTAAAGCATCTTTTATACCCACTGACTCTGAGCAGCCTG CAGATGGGGGCCTGGCGTTTGCTTCAGCCCTTCCCTGAGTGCAGTCCCCCCACAGCCACCAGCACCCTCATGATGCTGTGCTCTGCAGGC GAGGGGCACCACCACGTCCAAAGGCTGCCACACACACTGGTGGCTTTTCTGGGCCACATTCACCAAAAGCCAGGACTTCTGTGGGGCTGG TACAGGAGGCTCATGGAATTTCCTACACACTTCACCAAATGTTTGTTTACCTTTGAACTCCCTGCTTCTCATCTTTGATATGATTCTTCA CCAGGATTTTGTACAAAAATGATCATGGTTCTGGGGTGGGGAGAGGAAAGGGAGCACATATTTTGCTAAGAGGTATATATGCAGTACCTT TTATACACAGAAATACAAATAGAGCTTTTTCTAAGGCTTTCGGTTGCTGGTTGGGGGTGGGATATATGAAATTTCAGTTGAATTCTACAG GAAAGTGTTATATTAGCCAAAAACAGAAAAATGGTTTTTAAAATGCCAATGATTTGTAATTAAATTGTAGCAATTTTGGTCTCATGATAG TGTAATATCTCAGCAACAATGCAATAATTCACATTGAAACAGCGCTTCCATTCTGAACTCTGCTCTGCAAATGTCTTTTGGGTCCCGCTG TCAACCAAACTTGAATTTTCTTAAAAAAAAAATTATGTAACTCTTATCCAGGCATTTTAGAACTATGCAATTGTGATTTAAAATGCAACT TTGTGCTTTTAAAACATTATTGACCTTTTTTGTATATGGATAAACAACTTGGTTTTATTATCAATAGTACTTTGCATTTATAGCTATTAT TTTTAAAAGCTCAAAAAGTTTTTTAAAATGTCAAATTTTGAATAGTCATCAATAAGTAATTATCAAGTTTGGAAGGAAAGGTTGAAATGA CTCCGTTTCCTTATAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTTCCATGGCTAACTAGATTTAACCAGAATCCCGC CTTCCAGGCTCCTGTTCCCTTTTATTAGCTGCTGAATTTTATTCCCTTTTCCCAACTCCAGGTCCCTCAGTTGTCTTATATCTAAATCCT TTGCCAGGTCCCCACAATCCCAGCACCTGCCTCTGTGAGCTGCCCCCAGGCCCTCACCTTGGCCCTGGCCAGCCTCCTGTGCTCCTGCTG TCTGAAGGACTGGCCCCTCCCCCACTGCTGAAGCCACACGTACAGATCCTAAGCAACAGGGCCTTTTGCTGGGACGTATGCCTGGATTAT GGCCAACCGGGAAGAGAGAGATGTATCTTAAAAAGTGGAGGTGGACTTCTCCTACAGCTCTGACGGTAACTTAAATTGTTGCCAGCTTGA GGCAAGACAAGGGAATCATCTAGTTAGGGGTAACCATTAATTTATTTTATAAAGAAAGGAAATGCTGAAAGTCGTATTAGTACTGAGTTT AGTTGGAGAATTTAGATAAGTAAGTATCTTTTAGGTAATTCTAAAATTAAAATCCTACCCACCTCACTACAGGGTTCCTCATGAAGGTGG GCGGCCACCTGGCCTGGGCCACCAGCAGCACATGGAGCAGACCTGAGGGGCCTGGCAGGGGGCACTGACCTCAGGATCCCCAGGTGGGGG TTTTAACCATGGGTGGGATCTCAGCTTCTGCGCATACACTGACAATCTCACCTGTTCCTCAGTGTACTCCTCTGAAAAGAAGAAAGGATA ATATTTATCCAATCTGTGTTCTCCTGAGCTCCATCCTAGGGGTTTTTAATTTAACCAACAGCCATGTTGACAAAAGCCAACAATAAGCAT GTCTTATTCTAGCCCTGATCCCAACACTGAAAGCGAAGTACTTTATAAAGAAGCCAGCAATTATGAGGGTTTCTTTATGTTAGTAGGGGA AAAAATGGTAATAAAAGTACCAGTGTAGCAAGTGAAGACCAAATTTATAGCACTGTGCATTAGATAGCAAAATCAGGTTCTTAACAATGA AAAGTAAACCTCAAGTTTCTAAATCCATATGCAGATGGTTAGGCTGTCCCTCTCTTAGCAAATCTCTCAGCCTCCTTCTTTCCCAAGTGC CAAGGATCCCTGGAGTAAAGCTCTGGGGTCTGTGCTCTCTTTCTGTGAGGGGAAGGCTGCGGCCCTATTTGCCCCTCTCTAGCAAACACC CCCACCACCCTGCCGCTTCCTGTGGTTATTGAGCCAGCTAGGAGTTACTCATGGACTCTAACCTGGTTTTAGTCCCATGTACATCGTTGT TTTAGGTTTCATACTGAAGAGCCAATGGTTTATGTGGTTTTATTCTGTCTTAAATATAAGTTTCAAGGAAGGGAAAACAAAAGTGATAAA ATGATAGAACAGTCTAGAGGCCACTGTAAAGTCACCGCCACTTTACGTGTATGTCAGTCTTGGTGTTCTTGTATGAGTAAAATGGATGTA AAATCATAAAATCACAGTGAATGTTTCAGGCTACACTGGAAAAAGTATGCACTTAGAATTAAAGGAAATTGTATAATTCACCAAGATTTC TTTGTGTAGATCAGGGGTTGGCAACTATGACCCACAGGCTAAGACTGGTCAGCGGTCTGGTTTTTCACAGCCATGAGCTAAGTTACCTTT TTAAAGGGTTATATAAGTAATTACATCATATTTTTGATTTTGCCTTTGGCCCACACCACATAAAATATTCAATACCTGGCCTTTTTTTTT TTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGATAGAGTGCACTGGTGCGATTTTGGCTCACTGCAACCTCTTCCTCCTGGGTTCAAG CAATTCTCCCTGCCTCAGCCTCTAAGTAGCTGGGACTACAGGCACCCACTACCATGCCTTGCTAATTTTTGTATTTTTAATAGAGATGGG GTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGGGATCCGCCCGCCTTGGCCTCCCAAACTGCTGGGATTACAGGTGA GCCACTGCGCCCAGCCAATACCTGGCCTTTTAAGAAGTTTGCTGACTCCTGGTATGGATGACAGAAAATGGAATAACGTTTTGTTTCTCC AGTCTAGGAAAAGCAAGTCAGGTAGTGGATAGACTGACTGGCGTCCGGGGAGCCCAGGGTATGTGAGGGCCACGTGGATGGAAGCAAATG CCTCCTGCATAGCCCTTGGCTCTTTGTCCCACTTGGGAGGAGTCCATGGATGTAATATTTACAAAACAATTTTTTCCTTACCATTTGCAG AAAGCATTGCATATATTTCCTTTTAGCTCAGGAAACTGGCATGCCCCACCCTCTGCTACTCCATCAGATGTAAATACAATGACTATAAGC CGTACAACTCCCCTCTCTTAGAAACCTCAGCAGGACCACAGAGCAAGGGAGTCAAAGCTTTCTTAATTCTCTCCAGTAAATGACTCAACT AATTTGATTTTTTTAATTAAGTCAAAATATCAAGAGAAAAATTGCTACTAAAACTTACATTTTGATCCACACTGATGTGCAACACAAAAT GAAAGTTTTCACCTCCATTCCATTTTTTAAAAATTCACGGTCCACACTGAAACTTGCTGGGTTTTAGCAGGAGACAAAGGTGTCACCCAC GCTGTCCTCATCCTGCTCTCTCTGTCCCAGTGACGCTCCAGCATATGATCACTGCAGCCGGTCCCTGGCCCGTGCCGATTCTGCCACCTC CCAGCCACACACATTTGCAGACCCACAAGAAGAACTGTAGCCTTGATAATTTCAGTTCAGGCTGGAAAAATGCCATGCAATAATCTGGTT TGCTTTCAGTAAGTAGGCAACAAGTGAAAACTGTATAATTTTCATCACCTATTCTGCTGTTCTATCTAAAATGAGTGTACCTGTGGTTTG TGAACTGGGCCCTTGTTTGTGCCAGATCCTTCAAAGATGTTCCCTGTCAGGACACCTGTGGCCCTGCCCCTCCTCAGACACCTTCCCACT GGCATTCACGTTCCTTATATGCAGTGTTAGCCATCTTTGGCCTACGTGGACTTTTTTTGTAAATTACACCATTTCCAGACATTAAACTTT TTATATTATGAAATTTACCATGTAAAAAGAACTTCATATTTTTATTGAGATTGCTAAGGCACTTGGCCTTCCTCCTTTGTGATTTTCAGT >In-frame_XBP1_ENST00000344347_chr22_29195045_-_TTC28_ENST00000397906_chr22_29025818_-_11873nt ATGGTGGTGGTGGCAGCCGCGCCGAACCCGGCCGACGGGACCCCTAAAGTTCTGCTTCTGTCGGGGCAGCCCGCCTCCGCCGCCGGAGCC CCGGCCGGCCAGGCCCTGCCGCTCATGGTGCCAGCCCAGAGAGGGGCCAGCCCGGAGGCAGCGAGCGGGGGGCTGCCCCAGGCGCGCAAG CGACAGCGCCTCACGCACCTGAGCCCCGAGGAGAAGGCGCTGAGGAGGAAACTGAAAAACAGAGTAGCAGCTCAGACTGCCAGAGATCGA AAGAAGGCTCGAATGAGTGAGCTGGAACAGCAAGTGGTAGATTTAGAAGAAGAGATTCCTCTCTTTGGTGCTGACACTATTGGCCAGAGA AGTCCTGATGGACCGGTACTGAGCAAAGCTGAATTTGTTGAGAAAGTTCGTCAGAGTAATCAGGCCTGTCATGATGGAGATTTCCACACA GCTATTGTTCTGTATAATGAAGCCCTGGCTGTTGACCCTCAGAACTGCATCTTATACAGCAATAGATCTGCAGCCTACATGAAAATCCAG CAGTATGACAAGGCACTGGATGATGCAATCAAAGCTCGACTTCTCAATCCCAAGTGGCCAAAGGCATACTTCCGACAGGGTGTTGCCCTC CAGTACCTTGGACGTCATGCCGATGCCCTGGCAGCCTTTGCATCTGGACTGGCTCAAGACCCCAAGAGTCTCCAGCTTCTGGTGGGGATG GTGGAAGCCGCCATGAAATCTCCCATGAGAGACTCCCTCGAGCCCACTTATCAGCAGCTTCAGAAAATGAAACTGGACAAGAGTCCCTTT GTGGTCGTGTCTGTGGTTGGGCAGGAACTCCTGACAGCTGGCCATCATGGGGCCTCTGTGGTTGTCTTAGAAGCCGCACTGAAGATTGGC ACCTGCAGCCTCAAACTGAGAGGTTCTGTTTTCTCTGCCCTGAGCAGTGCTTACTGGTCTCTTGGAAATACAGAGAAGAGCACCGGATAT ATGCAGCAGGACTTGGATGTAGCCAAGACCTTAGGTGACCAGACAGGAGAATGCCGAGCTCATGGGAATCTGGGCTCTGCATTCTTCTCC AAAGGAAATTACCGGGAGGCTCTCACTAACCACAGGCATCAGTTGGTACTCGCCATGAAACTCAAAGATCGAGAGGCAGCTTCATCAGCC TTGAGCAGTCTGGGCCACGTGTACACAGCCATTGGAGACTACCCCAATGCACTGGCCAGTCACAAACAGTGTGTTCTTCTTGCCAAGCAA TCCAAAGATGAACTTTCTGAAGCCCGAGAACTTGGCAACATGGGAGCTGTGTATATTGCCATGGGTGACTTTGAGAATGCTGTGCAGTGC CATGAGCAGCATCTGAAGATAGCCAAGGACCTGGGGAACAAGCGAGAAGAGGCCCGGGCTTATAGCAACCTGGGCAGTGCCTATCACTAC CGGAGGAACTTTGACAAGGCCATGTCTTACCATAACTATGTCCTGGAGCTGGCACAGGAGTTGATGGAGAAGGCTATTGAGATGCGGGCC TATGCTGGACTAGGCCATGCTGCCAGGTGCATGCAGGATTTGGAGAGAGCTAAACAATACCATGAGCAGCAGCTGGGCATTGCTGAGGAT CTCAAGGACCGGGCTGCAGAGGGGCGAGCATCCTCCAATCTAGGAATCATACACCAGATGAAAGGTGATTATGACACTGCACTGAAACTC CACAAGACCCACCTGTGCATTGCCCAGGAGCTGAGTGATTATGCTGCCCAGGGCCGTGCCTATGGGAATATGGGCAATGCCTACAATGCC CTGGGCATGTACGACCAGGCGGTCAAATACCATCGGCAGGAGCTGCAGATCTCCATGGAAGTGAATGACCGCGCCTCACAGGCCTCCACA CATGGGAACCTTGCCGTGGCCTACCAGGCCCTGGGTGCCCATGACCGGGCCCTGCAACACTATCAGAACCACTTGAACATCGCCCGGGAG CTACGAGACATCCAGAGCGAGGCCCGGGCCCTCAGCAACCTGGGCAATTTCCACTGCTCTCGGGGAGAGTATGTCCAGGCTGCCCCCTAT TATGAACAGTACCTCCGGCTTGCTCCCGACCTTCAAGACATGGAAGGAGAAGGGAAGGTCTGCCACAATCTTGGCTATGCCCATTACTGC CTTGGAAACTATCAGGAGGCAGTGAAGTACTACGAACAGGATCTGGCACTGGCTAAAGACCTTCACGACAAGTTGAGCCAAGCAAAAGCC TACTGCAACTTGGGCCTAGCATTCAAGGCTCTGCTGAATTTCAGTAAAGCTGAAGAGTGTCAGAAGTACCTACTGTCCCTAGCCCAGTCT CTGAATAATTCCCAGGCTAAATTTCGAGCCCTAGGAAACCTGGGCGATATATTCATCTGTAAAAAAGATATAAATGGTGCAATAAAATTC TATGAGCAGCAACTGGGCTTAGCTCACCAGGTAAAGGACAGAAGATTAGAAGCCAGTGCATATGCAGCCCTGGGCACTGCATACCGAATG ATCCAGAAGTATGACAAGGCCCTGGGTTATCACACACAGGAACTGGAGGTATATCAGGAGCTGAGTGACTTGCCAGGGGAGTGCAGAGCT CATGGGCACCTGGCTGCTGTCTACATGGCCCTTGGGAAATACACAATGGCATTCAAGTGTTATGAAGAGCAACTGGATCTAGGGCAAAAG CTGAAGGATCCGAGTCTGGAAGCCCAGGTCTATGGCAACATGGGCATCACAAAGATGAACATGAATGTGATGGAAGAAGCCATTGGCTAC TTTGAGCAGCAATTGGCCATGCTGCAGCAGCTAAGTGGAAATGAGTCTGTGCTCGACAGGGGCCGGGCCTATGGCAACCTGGGGGATTGC TACGAAGCCCTGGGTGACTATGAGGAAGCTATCAAATACTATGAACAATATTTATCTGTCGCGCAGAGTCTGAATCGCATGCAAGACCAA GCCAAGGCTTACCGGGGCCTGGGAAATGGACACAGGGCAATGGGGAGCTTGCAGCAAGCCCTTGTGTGCTTTGAAAAGAGGCTCGTGGTT GCTCATGAACTTGGAGAGGCCTTCAATAAAGCCCAGGCCTATGGAGAGCTGGGAAGTCTGCACAGCCAATTAGGGAATTACGAACAAGCC ATTTCCTGCCTTGAACGCCAGCTGAACATTGCTAGAGATATGAAAGACCGAGCCCTGGAGAGTGACGCAGCCTGTGGCCTGGGGGGCGTT TACCAGCAGATGGGGGAGTATGACACAGCCCTGCAGTACCACCAGCTTGATCTACAGATAGCAGAGGAAACCAACAACCCCACGTGCCAG GGCCGAGCCTATGGGAACCTGGGCCTGACTTATGAATCCCTGGGCACCTTCGAGAGGGCTGTGGTCTATCAAGAACAGCACTTGAGCATT GCTGCACAGATGAATGACTTGGCGGCCAAGACGGTGTCATATAGTAGCCTTGGAAGGACCCATCATGCCTTGCAGAACTATTCCCAAGCA GTCATGTACTTACAGGAAGGTTTAAGGTTAGCTGAGCAACTGGGCCGAAGAGAAGATGAGGCAAAAATTCGCCATGGCCTTGGCCTCTCC CTTTGGGCTAGTGGAAACTTGGAGGAGGCCCAACACCAGCTTTATAGGGCATCAGCCTTGTTTGAAACAATCCGACATGAGGCACAGCTG AGCACGGACTACAAACTCTCCCTCTTTGACCTGCAGACATCATCCTACCAGGCCTTGCAGCGGGTGCTCGTCAGCCTAGGCCATCATGAT GAAGCCCTGGCTGTGGCAGAAAGGGGACGGACAAGGGCATTTGCTGATCTTCTGGTGGAACGACAAACAGGACAACAAGACTCCGACCCC TACTCCCCAGTCACTATTGATCAGATCTTAGAGATGGTAAATGGCCAGAGGGGACTAGTGCTTTACTATTCCCTGGCTGCAGGCTATCTG TATAGCTGGCTGCTGGCTCCTGGGGCAGGAATTGTGAAGTTTCATGAACACTACCTGGGTGAGAACACAGTGGAAAACTCAAGTGACTTC CAGGCCAGCAGCAGTGTAACCCTTCCAACAGCAACCGGCTCAGCCCTGGAGCAGCACATTGCCAGTGTCCGGGAGGCCCTGGGGGTGGAG TCTCACTACTCAAGGGCCTGTGCCAGCAGTGAGACAGAGAGTGAAGCGGGAGACATCATGGACCAGCAATTTGAAGAGATGAACAACAAA CTCAACTCGGTCACTGACCCCACTGGCTTTCTGCGGATGGTTCGCCGCAATAACCTGTTTAACAGGAGCTGCCAGAGCATGACGAGCCTG TTCAGTAACACTGTGTCACCGACCCAGGACGGGACCTCCTCTCTTCCCAGGAGGCAGAGCTCGTTTGCCAAGCCCCCGCTCCGTGCCCTG TATGACCTGCTCATCGCGCCCATGGAAGGGGGCCTGATGCACTCCAGCGGCCCCGTGGGCCGGCACCGGCAGCTCATCCTGGTTCTGGAG GGGGAGCTCTACCTCATTCCTTTCGCCCTCCTGAAGGGAAGCTCCTCCAATGAGTACCTCTACGAGCGCTTCGGCCTCCTTGCTGTCCCT TCCATCCGCTCCCTCAGCGTGCAGTCCAAGTCTCACTTACGGAAGAACCCGCCCACATACTCCAGCTCCACATCCATGGCGGCTGTCATC GGCAACCCCAAGCTACCATCGGCCGTGATGGACAGGTGGCTGTGGGGGCCCATGCCATCGGCCGAGGAAGAGGCCTACATGGTGTCCGAG CTGCTGGGCTGCCAGCCCCTAGTGGGCAGTGTGGCCACCAAGGAGAGGGTCATGAGTGCCCTGACCCAGGCTGAATGCGTCCACTTTGCC ACCCACATCTCCTGGAAGCTGTCGGCCTTGGTCCTCACGCCCAGCATGGACGGCAACCCTGCCAGCAGCAAGAGCTCCTTCGGCCACCCC TACACGATCCCTGAGTCCTTGCGGGTGCAGGACGATGCCAGTGATGGGGAGAGCATCTCGGACTGCCCGCCCCTGCAGGAGCTGCTGCTT ACTGCCGCCGACGTCCTGGACCTGCAGCTGCCTGTGAAGCTGGTGGTGCTTGGCTCCTCCCAGGAGTCCAACAGCAAAGTCACAGCCGAC GGGGTCATCGCGCTGACAAGGGCCTTCCTGGCTGCCGGCGCTCAGTGTGTCCTCGTGTCTCTGTGGCCTGTGCCAGTGGCTGCTTCTAAG ATGTTCATCCATGCCTTCTACTCATCCCTGCTGAACGGCCTGAAAGCCAGCGCCGCCCTGGGGGAGGCCATGAAGGTGGTGCAGAGCAGC AAGGCCTTCTCGCACCCCTCCAACTGGGCAGGGTTCATGCTCATCGGGAGTGACGTTAAGCTGAACAGCCCCTCATCACTCATCGGCCAG GCCCTCACAGAGATCCTGCAGCACCCGGAGCGTGCGCGGGACGCCCTGCGAGTGCTGCTGCACCTGGTGGAGAAATCCCTGCAGCGCATC CAGAATGGGCAGCGCAATGCCATGTACACATCCCAGCAGAGTGTGGAGAACAAAGTGGGCGGCATCCCTGGCTGGCAGGCCCTCCTCACC GCTGTGGGCTTCCGGCTGGACCCCCCAACCAGTGGCCTGCCAGCGGCTGTCTTCTTCCCAACCTCCGACCCGGGCGACCGGCTCCAGCAG TGCAGCAGCACACTCCAGTCCCTGCTGGGTCTGCCCAATCCTGCCCTCCAAGCCCTTTGCAAACTCATCACTGCCTCCGAGACGGGCGAG CAGCTCATCAGCCGGGCTGTTAAAAATATGGTTGGAATGCTCCACCAGGTGCTGGTTCAGCTCCAGGCTGGCGAGAAGGAGCAGGACTTG GCATCAGCTCCCATTCAGGTCTCCATCAGCGTCCAGCTGTGGCGGCTCCCGGGATGCCACGAGTTCCTGGCAGCTCTAGGTTTTGATCTC TGTGAAGTTGGTCAGGAGGAAGTAATCCTGAAAACCGGGAAGCAAGCTAATCGACGGACTGTGCACTTCGCGCTCCAGTCCCTGCTGTCT CTGTTTGATTCTACTGAGCTACCCAAGCGCCTCAGCCTTGACAGCTCCTCCTCCCTCGAGTCTCTTGCTTCTGCTCAGTCTGTTTCCAAC GCCCTGCCCTTGGGTTACCAGCAACCCCCCTTCTCTCCCACCGGTGCGGACAGCATCGCCTCAGATGCCATCTCTGTGTACAGTCTGAGC TCCATTGCCTCCTCAATGAGCTTTGTCTCCAAACCCGAGGGTGGATCAGAGGGTGGAGGCCCCGGAGGACGGCAGGACCATGACCGGTCC AAGAACGCTTACCTGCAGAGATCCACCCTGCCTAGGAGCCAGCTGCCTCCCCAGACCCGCCCTGCAGGCAACAAAGATGAAGAAGAATAT GAAGGGTTTTCTATCATCAGTAACGAGCCCTTGGCGACCTACCAAGAAAACCGAAACACATGCTTCTCACCAGACCACAAACAACCCCAA CCTGGGACAGCCGGAGGCATGAGAGTCTCGGTGAGCTCCAAAGGGAGCATCAGCACTCCAAATTCTCCAGTGAAAATGACTCTGATTCCC AGCCCCAACTCACCCTTCCAAAAGGTGGGAAAACTAGCAAGCTCAGATACAGGAGAATCAGACCAGTCTAGCACAGAAACGGACAGTACC GTGAAATCCCAAGAAGAAAGCAACCCAAAACTGGATCCACAAGAGTTAGCCCAGAAAATTCTGGAGGAGACACAGAGTCATCTCATTGCG GTGGAGCGTCTTCAGAGGAGCGGCGGCCAGGTGAGCAAGAGTAATAACCCTGAAGACGGCGTTCAGGCGCCCAGCAGCACTGCTGTCTTC AGAGCGTCAGAAACCAGTGCGTTCAGCAGGCCTGTTCTCTCCCATCAGAAGAGTCAGCCATCACCAGTCACTGTTAAACCAAAGCCCCCA GCCAGGAGCTCCTCCCTGCCCAAGGTGAGTTCCGGATATAGCAGCCCCACCACCTCAGAGATGTCCATCAAAGACAGCCCGAGCCAGCAC AGTGGCCGGCCATCGCCCGGCTGCGACTCACAGACTTCCCAGCTGGACCAGCCTCTCTTTAAACTGAAGTACCCCAGCTCTCCTTACAGC GCTCACATTTCCAAATCACCAAGGAACATGTCCCCAAGCTCCGGCCACCAGTCTCCTGCTGGCAGTGCACCCTCCCCAGCTCTCTCCTAC TCCTCAGCTGGATCTGCTCGCTCAAGTCCAGCAGACGCTCCCGACATAGACAAACTGAAAATGGCAGCCATTGATGAAAAGGTGCAGGCT GTCCATAACCTGAAGATGTTCTGGCAGAGCACACCCCAGCATTCCACAGGGCCAATGAAGATCTTCCGGGGGGCTCCTGGCACGATGACT TCCAAAAGGGATGTCCTCAGTCTGTTGAATTTGTCACCACGGCACAATAAGAAGGAGGAGGGAGTGGATAAGCTTGAACTGAAGGAGCTG TCCCTGCAGCAGCATGACGGAGCTCCACCGAAAGCCCCTCCCAACGGACACTGGCGCACCGAGACCACCTCGCTGGGCTCACTGCCGCTG CCCGCCGGCCCTCCCGCCACAGCCCCCGCGCGCCCTTTGAGGCTTCCTTCTGGAAATGGCTACAAGTTCCTGTCTCCAGGAAGATTTTTC CCTTCTTCCAAATGCTAAAGCATCTTTTATACCCACTGACTCTGAGCAGCCTGCAGATGGGGGCCTGGCGTTTGCTTCAGCCCTTCCCTG AGTGCAGTCCCCCCACAGCCACCAGCACCCTCATGATGCTGTGCTCTGCAGGCGAGGGGCACCACCACGTCCAAAGGCTGCCACACACAC TGGTGGCTTTTCTGGGCCACATTCACCAAAAGCCAGGACTTCTGTGGGGCTGGTACAGGAGGCTCATGGAATTTCCTACACACTTCACCA AATGTTTGTTTACCTTTGAACTCCCTGCTTCTCATCTTTGATATGATTCTTCACCAGGATTTTGTACAAAAATGATCATGGTTCTGGGGT GGGGAGAGGAAAGGGAGCACATATTTTGCTAAGAGGTATATATGCAGTACCTTTTATACACAGAAATACAAATAGAGCTTTTTCTAAGGC TTTCGGTTGCTGGTTGGGGGTGGGATATATGAAATTTCAGTTGAATTCTACAGGAAAGTGTTATATTAGCCAAAAACAGAAAAATGGTTT TTAAAATGCCAATGATTTGTAATTAAATTGTAGCAATTTTGGTCTCATGATAGTGTAATATCTCAGCAACAATGCAATAATTCACATTGA AACAGCGCTTCCATTCTGAACTCTGCTCTGCAAATGTCTTTTGGGTCCCGCTGTCAACCAAACTTGAATTTTCTTAAAAAAAAAATTATG TAACTCTTATCCAGGCATTTTAGAACTATGCAATTGTGATTTAAAATGCAACTTTGTGCTTTTAAAACATTATTGACCTTTTTTGTATAT GGATAAACAACTTGGTTTTATTATCAATAGTACTTTGCATTTATAGCTATTATTTTTAAAAGCTCAAAAAGTTTTTTAAAATGTCAAATT TTGAATAGTCATCAATAAGTAATTATCAAGTTTGGAAGGAAAGGTTGAAATGACTCCGTTTCCTTATAAGCAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAATTTCCATGGCTAACTAGATTTAACCAGAATCCCGCCTTCCAGGCTCCTGTTCCCTTTTATTAGCTGCTGAAT TTTATTCCCTTTTCCCAACTCCAGGTCCCTCAGTTGTCTTATATCTAAATCCTTTGCCAGGTCCCCACAATCCCAGCACCTGCCTCTGTG AGCTGCCCCCAGGCCCTCACCTTGGCCCTGGCCAGCCTCCTGTGCTCCTGCTGTCTGAAGGACTGGCCCCTCCCCCACTGCTGAAGCCAC ACGTACAGATCCTAAGCAACAGGGCCTTTTGCTGGGACGTATGCCTGGATTATGGCCAACCGGGAAGAGAGAGATGTATCTTAAAAAGTG GAGGTGGACTTCTCCTACAGCTCTGACGGTAACTTAAATTGTTGCCAGCTTGAGGCAAGACAAGGGAATCATCTAGTTAGGGGTAACCAT TAATTTATTTTATAAAGAAAGGAAATGCTGAAAGTCGTATTAGTACTGAGTTTAGTTGGAGAATTTAGATAAGTAAGTATCTTTTAGGTA ATTCTAAAATTAAAATCCTACCCACCTCACTACAGGGTTCCTCATGAAGGTGGGCGGCCACCTGGCCTGGGCCACCAGCAGCACATGGAG CAGACCTGAGGGGCCTGGCAGGGGGCACTGACCTCAGGATCCCCAGGTGGGGGTTTTAACCATGGGTGGGATCTCAGCTTCTGCGCATAC ACTGACAATCTCACCTGTTCCTCAGTGTACTCCTCTGAAAAGAAGAAAGGATAATATTTATCCAATCTGTGTTCTCCTGAGCTCCATCCT AGGGGTTTTTAATTTAACCAACAGCCATGTTGACAAAAGCCAACAATAAGCATGTCTTATTCTAGCCCTGATCCCAACACTGAAAGCGAA GTACTTTATAAAGAAGCCAGCAATTATGAGGGTTTCTTTATGTTAGTAGGGGAAAAAATGGTAATAAAAGTACCAGTGTAGCAAGTGAAG ACCAAATTTATAGCACTGTGCATTAGATAGCAAAATCAGGTTCTTAACAATGAAAAGTAAACCTCAAGTTTCTAAATCCATATGCAGATG GTTAGGCTGTCCCTCTCTTAGCAAATCTCTCAGCCTCCTTCTTTCCCAAGTGCCAAGGATCCCTGGAGTAAAGCTCTGGGGTCTGTGCTC TCTTTCTGTGAGGGGAAGGCTGCGGCCCTATTTGCCCCTCTCTAGCAAACACCCCCACCACCCTGCCGCTTCCTGTGGTTATTGAGCCAG CTAGGAGTTACTCATGGACTCTAACCTGGTTTTAGTCCCATGTACATCGTTGTTTTAGGTTTCATACTGAAGAGCCAATGGTTTATGTGG TTTTATTCTGTCTTAAATATAAGTTTCAAGGAAGGGAAAACAAAAGTGATAAAATGATAGAACAGTCTAGAGGCCACTGTAAAGTCACCG CCACTTTACGTGTATGTCAGTCTTGGTGTTCTTGTATGAGTAAAATGGATGTAAAATCATAAAATCACAGTGAATGTTTCAGGCTACACT GGAAAAAGTATGCACTTAGAATTAAAGGAAATTGTATAATTCACCAAGATTTCTTTGTGTAGATCAGGGGTTGGCAACTATGACCCACAG GCTAAGACTGGTCAGCGGTCTGGTTTTTCACAGCCATGAGCTAAGTTACCTTTTTAAAGGGTTATATAAGTAATTACATCATATTTTTGA TTTTGCCTTTGGCCCACACCACATAAAATATTCAATACCTGGCCTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGATA GAGTGCACTGGTGCGATTTTGGCTCACTGCAACCTCTTCCTCCTGGGTTCAAGCAATTCTCCCTGCCTCAGCCTCTAAGTAGCTGGGACT ACAGGCACCCACTACCATGCCTTGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTG ACCTCAGGGGATCCGCCCGCCTTGGCCTCCCAAACTGCTGGGATTACAGGTGAGCCACTGCGCCCAGCCAATACCTGGCCTTTTAAGAAG TTTGCTGACTCCTGGTATGGATGACAGAAAATGGAATAACGTTTTGTTTCTCCAGTCTAGGAAAAGCAAGTCAGGTAGTGGATAGACTGA CTGGCGTCCGGGGAGCCCAGGGTATGTGAGGGCCACGTGGATGGAAGCAAATGCCTCCTGCATAGCCCTTGGCTCTTTGTCCCACTTGGG AGGAGTCCATGGATGTAATATTTACAAAACAATTTTTTCCTTACCATTTGCAGAAAGCATTGCATATATTTCCTTTTAGCTCAGGAAACT GGCATGCCCCACCCTCTGCTACTCCATCAGATGTAAATACAATGACTATAAGCCGTACAACTCCCCTCTCTTAGAAACCTCAGCAGGACC ACAGAGCAAGGGAGTCAAAGCTTTCTTAATTCTCTCCAGTAAATGACTCAACTAATTTGATTTTTTTAATTAAGTCAAAATATCAAGAGA AAAATTGCTACTAAAACTTACATTTTGATCCACACTGATGTGCAACACAAAATGAAAGTTTTCACCTCCATTCCATTTTTTAAAAATTCA CGGTCCACACTGAAACTTGCTGGGTTTTAGCAGGAGACAAAGGTGTCACCCACGCTGTCCTCATCCTGCTCTCTCTGTCCCAGTGACGCT CCAGCATATGATCACTGCAGCCGGTCCCTGGCCCGTGCCGATTCTGCCACCTCCCAGCCACACACATTTGCAGACCCACAAGAAGAACTG TAGCCTTGATAATTTCAGTTCAGGCTGGAAAAATGCCATGCAATAATCTGGTTTGCTTTCAGTAAGTAGGCAACAAGTGAAAACTGTATA ATTTTCATCACCTATTCTGCTGTTCTATCTAAAATGAGTGTACCTGTGGTTTGTGAACTGGGCCCTTGTTTGTGCCAGATCCTTCAAAGA TGTTCCCTGTCAGGACACCTGTGGCCCTGCCCCTCCTCAGACACCTTCCCACTGGCATTCACGTTCCTTATATGCAGTGTTAGCCATCTT TGGCCTACGTGGACTTTTTTTGTAAATTACACCATTTCCAGACATTAAACTTTTTATATTATGAAATTTACCATGTAAAAAGAACTTCAT |
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FusionGenePPI for XBP1_TTC28 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| XBP1 | ESR1, FOS, GLI1, H1F0, HDGF, RBL2, SRSF1, SSX4, NR0B2, FUBP3, H1FX, TRIP4, ZNF580, PCBD2, ZNF440, PSMA5, PSMA6, PSMA8, ATF6B, ATF6, XBP1, CREBZF, HM13, DERL1, UBE2I, KAT2B, KAT2A, MCM2, CROCC, CCDC102B, MTNR1B | TTC28 | BRE, SSPO, UBC, YWHAB, BSG, HLA-B, SDF4, NCK2, PRMT2, NTRK1, TP53, MED4, MED23, CEP120, CEP152, NINL, NIN, SASS6, P4HA2, HTRA4, TSPYL6, CD79A, PCDHGB1, DOCK5, ICAM1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for XBP1_TTC28 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for XBP1_TTC28 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | XBP1 | C0036341 | Schizophrenia | 3 | PSYGENET |
| Hgene | XBP1 | C0005586 | Bipolar Disorder | 2 | PSYGENET |
| Hgene | XBP1 | C0015695 | Fatty Liver | 1 | CTD_human |
| Hgene | XBP1 | C0017638 | Glioma | 1 | CTD_human |
| Hgene | XBP1 | C0021655 | Insulin Resistance | 1 | CTD_human |
| Hgene | XBP1 | C0271650 | Impaired glucose tolerance | 1 | CTD_human |
| Hgene | XBP1 | C0400966 | Non-alcoholic Fatty Liver Disease | 1 | CTD_human |
| Hgene | XBP1 | C0853193 | Bipolar I disorder | 1 | PSYGENET |
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